Angiotensin-converting enzyme 2
UniProt Q9BYF1 · gene ACE2 · Homo sapiens · 805 residues
497evidence items
0mapped to a state
0states
8techniques
7sources
0conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | nmr_structure | nmr_shifts | saxs_sans | force_spectroscopy | af_prediction | md | Total |
|---|---|---|---|---|---|---|---|---|---|---|
| No states defined yet. | ||||||||||
Unmapped evidence: 497 of 497 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 1 | 0 |
| DisProt | 1 | 0 |
| MDDB | 100 | 0 |
| RCSB PDB | 359 | 0 |
| SASBDB | 3 | 0 |
| SMASH-BIO | 32 | 0 |
Structure
No state models are exported for this protein yet. Observed states export the representative PDB entry; inferred states need fitted models, not yet built.
States and transitions
No states defined.
| State | Basis | Parent | Description |
|---|
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-1R4L-1 RCSB PDB | xray | resolution: 3 Å | in vitro · pH 7.5 · ligands CL, NAG, XX5, ZN Inhibitor Bound Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2) · angiotensin I converting enzyme 2 (chains A) | unmapped |
| EV-PDB-22HG-2 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro · ligands NAG, ZN, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 BA.3.2.2(RE.2.2) RBD in complex with human ACE2 and monoclonal antibody S2H97 · Processed angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-2AJF-1 RCSB PDB | xray | resolution: 2.9 Å | in vitro · -173.15 °C · pH 7.5 · ligands CL, NAG, ZN, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS coronavirus spike receptor-binding domain complexed with its receptor · Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2) (chains A,B) | unmapped |
| EV-PDB-3D0G-1 RCSB PDB | xray | resolution: 2.8 Å | in vitro · pH 8.5 · ligands CL, NAG, NDG, ZN Crystal structure of spike protein receptor-binding domain from the 2002-2003 SARS coronavirus human strain complexed with human-civet chimeric receptor ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-3D0H-1 RCSB PDB | xray | resolution: 3.1 Å | in vitro · pH 8.5 · ligands CL, NAG, NDG, ZN Crystal structure of spike protein receptor-binding domain from the 2002-2003 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-3D0I-1 RCSB PDB | xray | resolution: 2.9 Å | in vitro · pH 8.5 · ligands CL, NAG, NDG, ZN Crystal structure of spike protein receptor-binding domain from the 2005-2006 SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-3KBH-1 RCSB PDB | xray | resolution: 3.31 Å | in vitro · -173.15 °C · pH 5.5 · ligands NAG Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor · Angiotensin-converting enzyme 2 (chains A,B,C,D) | unmapped |
| EV-PDB-3SCI-1 RCSB PDB | xray | resolution: 2.9 Å | in vitro · -173.15 °C · pH 8.5 · ligands CL, ZN Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus human strain complexed with human receptor ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-3SCJ-1 RCSB PDB | xray | resolution: 3 Å | in vitro · -173.15 °C · pH 8.5 · ligands CL, ZN Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus civet strain complexed with human receptor ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-3SCK-1 RCSB PDB | xray | resolution: 3 Å | in vitro · -173.15 °C · pH 8.5 · ligands CL, ZN Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2 · Angiotensin-converting enzyme 2 chimera (chains A,B) | unmapped |
| EV-PDB-3SCL-1 RCSB PDB | xray | resolution: 3 Å | in vitro · -173.15 °C · pH 8.5 · ligands CL, ZN Crystal structure of spike protein receptor-binding domain from SARS coronavirus epidemic strain complexed with human-civet chimeric receptor ACE2 · Angiotensin-converting enzyme 2 chimera (chains A,B) | unmapped |
| EV-PDB-6ACG-2 RCSB PDB | cryoem | resolution: 5.4 Å | in vitro Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 1 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-6ACJ-2 RCSB PDB | cryoem | resolution: 4.2 Å | in vitro Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 2 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-6CS2-2 RCSB PDB | cryoem | resolution: 4.4 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS Spike Glycoprotein - human ACE2 complex, Stabilized variant, all ACE2-bound particles · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-6LZG-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN Structure of novel coronavirus spike receptor-binding domain complexed with its receptor ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-6M0J-1 RCSB PDB | xray | resolution: 2.45 Å | in vitro · -173.15 °C · ligands CL, NAG, ZN Crystal structure of SARS-CoV-2 spike receptor-binding domain bound with ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-6M17-2 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands LEU, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose The 2019-nCoV RBD/ACE2-B0AT1 complex · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-6M18-2 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands 3PH, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-B0AT1 complex · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-7A91-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Dissociated S1 domain of SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7A92-1 RCSB PDB | cryoem | resolution: 4.2 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Dissociated S1 domain of SARS-CoV-2 Spike bound to ACE2 (Unmasked Refinement) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7A94-2 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7A95-2 RCSB PDB | cryoem | resolution: 4.3 Å | in vitro SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound and 1 RBD Erect in Clockwise Direction · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7A96-2 RCSB PDB | cryoem | resolution: 4.8 Å | in vitro SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound and 1 RBD Erect in Anticlockwise Direction · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7A97-2 RCSB PDB | cryoem | resolution: 4.4 Å | in vitro SARS-CoV-2 Spike Glycoprotein with 2 ACE2 Bound · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7A98-2 RCSB PDB | cryoem | resolution: 5.4 Å | in vitro SARS-CoV-2 Spike Glycoprotein with 3 ACE2 Bound · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7BH9-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands NAG, ZN SARS-CoV-2 RBD-62 in complex with ACE2 peptidase domain · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7CT5-2 RCSB PDB | cryoem | resolution: 4 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S protein of SARS-CoV-2 in complex bound with T-ACE2 · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7DDO-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, ZN Cryo-EM structure of human ACE2 and GD/1/2019 RBD · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7DDP-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, ZN Cryo-EM structure of human ACE2 and GX/P2V/2017 RBD · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7DF4-1 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 S-ACE2 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7DMU-1 RCSB PDB | xray | resolution: 3.2 Å | in vitro · -173.15 °C · ligands NAG, SO4, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 spike receptor-binding domain complexed with high affinity ACE2 mutant 3N39 · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7DQA-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands CL, NAG, ZN Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7DRV-1 RCSB PDB | xray | resolution: 3.09 Å | in vitro · -173.15 °C · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structural basis of SARS-CoV-2-closely-related bat coronavirus RaTG13 to hACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-7DWX-2 RCSB PDB | cryoem | resolution: 8.3 Å | in vitro · ligands LEU, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Conformation 1 of S-ACE2-B0AT1 ternary complex · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-7DX4-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro · ligands NAG The structure of FC08 Fab-hA.CE2-RBD complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7DX5-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 2 (1 up RBD and 1 PD bound) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7DX6-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 3 (2 up RBD and 1 PD bound) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7DX7-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 1 (1 up RBD and 1 PD bound) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7DX8-2 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 2 (2 up RBD and 2 PD bound) · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7DX9-2 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 3 (3 up RBD and 2 PD bound) · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7E7E-1 RCSB PDB | xray | resolution: 3.8 Å | in vitro · 19.85 °C · ligands ZN The co-crystal structure of ACE2 with Fab · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-7EDJ-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain · Angiotensin-converting enzyme 2 (ACE2) ectodomain (chains I,J,K) | unmapped |
| EV-PDB-7EFP-1 RCSB PDB | xray | resolution: 2.698 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (S19W,N330Y) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7EFR-1 RCSB PDB | xray | resolution: 2.494 Å | in vitro · -173.15 °C · pH 7.5 · ligands NAG Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (T27W,N330Y) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7EKC-1 RCSB PDB | xray | resolution: 2.8 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 Gamma variant spike receptor-binding domain complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-6VW1-1 RCSB PDB | xray | resolution: 2.68 Å | in vitro · -173.15 °C · ligands CL, EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 chimeric receptor-binding domain complexed with its receptor human ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-6M1D-2 RCSB PDB | cryoem | resolution: 4.5 Å | in vitro ACE2-B0AT1 complex, open conformation · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-6ACK-2 RCSB PDB | cryoem | resolution: 4.5 Å | in vitro Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 3 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-28KD-1 RCSB PDB | xray | resolution: 2.02 Å | in vitro · -173.15 °C · pH 7 · ligands ZN ACE2 extracellular domain in complex with the macrocyclic peptide GR3.1.2 · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-1R42-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -133.15 °C · pH 8.5 · ligands CL, NAG, ZN Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2) · angiotensin I converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7EKE-1 RCSB PDB | xray | resolution: 2.7 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN Structure of SARS-CoV-2 spike receptor-binding domain F486L mutation complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7EKF-1 RCSB PDB | xray | resolution: 2.85 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 Alpha variant spike receptor-binding domain complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7EKG-1 RCSB PDB | xray | resolution: 2.63 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 Beta variant spike receptor-binding domain complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7FDH-1 RCSB PDB | cryoem | resolution: 3.72 Å | in vitro · ligands NAG SARS-COV-2 Spike RBDMACSp25 binding to hACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7FDI-1 RCSB PDB | cryoem | resolution: 3.12 Å | in vitro · ligands NAG SARS-COV-2 Spike RBDMACSp36 binding to hACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7FEM-2 RCSB PDB | cryoem | resolution: 4.1 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 B.1.1.7 S-ACE2 complex · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7JVO-2 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -193.15 °C Importin alpha bound to the C-terminus of ACE2 · ARG-LYS-LYS-LYS-ASN-LYS-ALA (chains B) | unmapped |
| EV-PDB-7KJ2-2 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Spike Glycoprotein with one ACE2 Bound · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7KJ3-2 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Spike Glycoprotein with two ACE2 Bound · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7KJ4-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Spike Glycoprotein with three ACE2 Bound · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7KMS-1 RCSB PDB | cryoem | resolution: 3.64 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of triple ACE2-bound SARS-CoV-2 trimer spike at pH 7.4 · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7KMZ-2 RCSB PDB | cryoem | resolution: 3.62 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of double ACE2-bound SARS-CoV-2 trimer Spike at pH 7.4 · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7KNB-2 RCSB PDB | cryoem | resolution: 3.93 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 7.4 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7KNE-2 RCSB PDB | cryoem | resolution: 3.85 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7KNH-2 RCSB PDB | cryoem | resolution: 3.74 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM Structure of Double ACE2-Bound SARS-CoV-2 Trimer Spike at pH 5.5 · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7KNI-2 RCSB PDB | cryoem | resolution: 3.91 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 5.5 · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7L0N-5 RCSB PDB | xray | resolution: 2.78 Å | in vitro · -173.15 °C · pH 8.5 · ligands CL, NA, NAG, PG4, PG5, PGE, SO4, ZN, branched: alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity · Angiotensin-converting enzyme 2 (chains E,F) | unmapped |
| EV-PDB-7LO4-1 RCSB PDB | xray | resolution: 2.465 Å | in vitro · -173.15 °C · pH 7 · ligands EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 spike receptor-binding domain with a G485R mutation in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7MJN-2 RCSB PDB | cryoem | resolution: 3.29 Å | in vitro · ligands NAG Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7NXC-1 RCSB PDB | xray | resolution: 3.14 Å | in vitro · -173.15 °C · pH 7 · ligands NAG Crystal structure of the receptor binding domain of SARS-CoV-2 P.1 variant Spike glycoprotein in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7P19-1 RCSB PDB | xray | resolution: 3.24 Å | in vitro · -173.15 °C · ligands CL, EDO, NAG, ZN Crystal structure of SARS-CoV-2 RBD Q498Y complexed with human ACE2 · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-7P55-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 2.5 NMR structure of human ACE2 21-42 fragment in HFIP/water 50/50 v/v · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7P8I-1 RCSB PDB | xray | resolution: 4.5 Å | in vitro · -173.15 °C · pH 8.5 · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 1 · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7P8J-1 RCSB PDB | xray | resolution: 6.585 Å | in vitro · -173.15 °C · pH 6.9 · ligands branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 2 · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7R10-1 RCSB PDB | cryoem | resolution: 4 Å | in vitro · ligands NAG, ZN Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7R11-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro · ligands NAG, ZN Dissociated S1 domain of Beta Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7R12-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, ZN Dissociated S1 domain of Mink Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7R1A-2 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Furin Cleaved Alpha Variant SARS-CoV-2 Spike in complex with 3 ACE2 · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7RPV-1 RCSB PDB | xray | resolution: 3.54 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN Crystal structure of affinity-enhancing and catalytically inactive ACE2 in complex with SARS-CoV-2 RBD · Processed angiotensin-converting enzyme 2 (chains A,B,C,D) | unmapped |
| EV-PDB-7SN0-1 RCSB PDB | xray | resolution: 3.08 Å | in vitro · -193.15 °C · pH 8.5 · ligands CL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of spike protein receptor binding domain of escape mutant SARS-CoV-2 from immunocompromised patient (d146*) in complex with human receptor ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-7SXX-2 RCSB PDB | cryoem | resolution: 2.66 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SXY-2 RCSB PDB | cryoem | resolution: 2.79 Å | in vitro · ligands NAG Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SXZ-2 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the SARS-CoV-2 D614G,L452R mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY0-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands NAG Cryo-EM structure of the SARS-CoV-2 D614G,L452R mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY1-2 RCSB PDB | cryoem | resolution: 2.83 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the SARS-CoV-2 D614G,N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY2-2 RCSB PDB | cryoem | resolution: 3.11 Å | in vitro · ligands NAG Cryo-EM structure of the SARS-CoV-2 D614G,N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY3-2 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY4-2 RCSB PDB | cryoem | resolution: 3.35 Å | in vitro · ligands NAG Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY5-2 RCSB PDB | cryoem | resolution: 2.59 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement) · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7SY6-2 RCSB PDB | cryoem | resolution: 2.81 Å | in vitro · ligands NAG Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY7-2 RCSB PDB | cryoem | resolution: 2.81 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7SY8-2 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro · ligands NAG Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7T9K-2 RCSB PDB | cryoem | resolution: 2.45 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7R0Z-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro · ligands NAG, ZN Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7PKI-1 RCSB PDB | xray | resolution: 2.94234 Å | in vitro · -193.15 °C · pH 8.5 · ligands CL, GOL, NAG, PEG, SO4, TRS, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of human ACE2 bound to the spike receptor-binding domain from a cave bat sarbecovirus closely related to SARS-CoV-2. · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7MJM-2 RCSB PDB | cryoem | resolution: 2.83 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7L7F-1 RCSB PDB | cryoem | resolution: 3.24 Å | in vitro Cryo-EM structure of human ACE2 receptor bound to protein encoded by vaccine candidate BNT162b1 · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-7KMB-1 RCSB PDB | cryoem | resolution: 3.39 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-RBD Focused Refinement Using Symmetry Expansion of Applied C3 for Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 7.4 · Angiotensin-converting enzyme 2 (chains F) | unmapped |
| EV-PDB-7FDG-1 RCSB PDB | cryoem | resolution: 3.69 Å | in vitro · ligands NAG SARS-COV-2 Spike RBDMACSp6 binding to hACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7EKH-1 RCSB PDB | xray | resolution: 2.4 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7T9L-2 RCSB PDB | cryoem | resolution: 2.66 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7TEW-2 RCSB PDB | cryoem | resolution: 3.52 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Delta (B.1.617.2) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7TEX-2 RCSB PDB | cryoem | resolution: 3.27 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Delta (B.1.617.2) spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7TEZ-2 RCSB PDB | cryoem | resolution: 3.27 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7TF0-2 RCSB PDB | cryoem | resolution: 3.02 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-7TN0-3 RCSB PDB | xray | resolution: 2.85 Å | in vitro · -173.15 °C · ligands CL, EDO, NAG, ZN SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab · Angiotensin-converting enzyme 2 (chains E,F) | unmapped |
| EV-PDB-7U0N-1 RCSB PDB | xray | resolution: 2.61 Å | in vitro · -173.15 °C · ligands CL, EDO, MG, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric omicron RBD (strain BA.1) complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-7UFK-1 RCSB PDB | xray | resolution: 2.38 Å | in vitro · -173.15 °C · ligands CL, EDO, NA, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric omicron RBD (strain BA.2) complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-7V61-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-7V80-2 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Local refinement of SARS-CoV-2 S-Beta variant (B.1.351) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain · Angiotensin-converting enzyme 2,Green fluorescent protein (chains F) | unmapped |
| EV-PDB-7V82-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 1 · Angiotensin-converting enzyme 2,Green fluorescent protein (chains D,E,F) | unmapped |
| EV-PDB-7V83-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 2 · Angiotensin-converting enzyme 2,Green fluorescent protein (chains D,E,F) | unmapped |
| EV-PDB-7V84-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Local refinement of SARS-CoV-2 S-Gamma variant (P.1) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain · Angiotensin-converting enzyme 2,Green fluorescent protein (chains F) | unmapped |
| EV-PDB-7V86-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form · Angiotensin-converting enzyme 2,Green fluorescent protein (chains F,G,H) | unmapped |
| EV-PDB-7V87-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Local refinement of SARS-CoV-2 S-Kappa variant (B.1.617.1) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain · Angiotensin-converting enzyme 2,Angiotensin-converting enzyme 2 (ACE2) ectodomain (chains F) | unmapped |
| EV-PDB-7V88-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form · Angiotensin-converting enzyme 2,Angiotensin-converting enzyme 2 (ACE2) ectodomain (chains F,G) | unmapped |
| EV-PDB-7V89-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 1 · Angiotensin-converting enzyme 2,Angiotensin-converting enzyme 2 (ACE2) ectodomain (chains F,G,H) | unmapped |
| EV-PDB-7V8A-2 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 2 · Angiotensin-converting enzyme 2,Angiotensin-converting enzyme 2 (ACE2) ectodomain (chains F,G,H) | unmapped |
| EV-PDB-7V8B-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Local refinement of SARS-CoV-2 S-Delta variant (B.1.617.2) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain · Angiotensin-converting enzyme 2,Angiotensin-converting enzyme 2 (ACE2) ectodomain (chains F) | unmapped |
| EV-PDB-7VIB-1 RCSB PDB | xray | resolution: 3.2 Å | in vitro · -173.15 °C · ligands ZN Crystal structure of human ACE2 and GX/P2V RBD · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7VX4-1 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro · ligands NAG, ZN ACE2-RBD in SARS-CoV-2 Beta variant S-ACE2 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7VX5-1 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro · ligands NAG, ZN ACE2-RBD in SARS-CoV-2 Kappa variant S-ACE2 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7VX9-2 RCSB PDB | cryoem | resolution: 4 Å | in vitro SARS-CoV-2 Kappa variant spike protein in complex wth ACE2, state C1 · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7VXA-2 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro SARS-CoV-2 Kappa variant spike protein in complex with ACE2, state C2a · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7VXB-2 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro SARS-CoV-2 Kappa variant spike protein in C2b state · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7VXC-2 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro SARS-CoV-2 Kappa variant spike protein in C3 state · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7VXD-2 RCSB PDB | cryoem | resolution: 4 Å | in vitro SARS-CoV-2 spike protein in complex with ACE2, Beta variant, C1 state · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7VXF-2 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro SARS-CoV-2 spike protein in complex with ACE2, Beta variant, C2B state · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7VXK-2 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro SARS-CoV-2 spike protein in complex with ACE2, Beta variant, C2A state · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7VXM-2 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro SARS-CoV-2 spike protein in complex with ACE2, Beta variant, C3 state · Angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-7W98-2 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro SARS-CoV-2 Delta S-ACE2-C1 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7W99-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro SARS-CoV-2 Delta S-ACE2-C2a · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-7W9B-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro SARS-CoV-2 Delta S-ACE2-C2b · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7W9C-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro SARS-CoV-2 Delta S-ACE2-C3 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7W9I-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro SARS-CoV-2 Delta S-RBD-ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WBL-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, ZN Cryo-EM structure of human ACE2 complexed with SARS-CoV-2 Omicron RBD · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WBP-1 RCSB PDB | xray | resolution: 3 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron variant spike glycoprotein in complex with its receptor human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WBQ-1 RCSB PDB | xray | resolution: 3.34 Å | in vitro · -173.15 °C · pH 6.5 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant spike glycoprotein in complex with its receptor human ACE2 · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7WGB-2 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Neutral Omicron Spike Trimer in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains D,F) | unmapped |
| EV-PDB-7WGC-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro · ligands NAG Neutral Omicron Spike Trimer in complex with ACE2. · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WHH-1 RCSB PDB | xray | resolution: 2.6 Å | in vitro · -173.15 °C · ligands CL, NAG, ZN, branched: alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of SARS-CoV-2 omicron RBD and human ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WK4-1 RCSB PDB | cryoem | resolution: 3.69 Å | in vitro Cryo-EM structure of SARS-CoV-2 Omicron spike protein with ACE2, C1 state · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WK5-1 RCSB PDB | cryoem | resolution: 3.66 Å | in vitro Cryo-EM structure of Omicron S-ACE2, C2 state · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WK6-2 RCSB PDB | cryoem | resolution: 3.67 Å | in vitro Cryo-EM structure of SARS-CoV-2 Omicron spike protein with human ACE2 (focus refinement on RBD-1/ACE2) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WNM-1 RCSB PDB | xray | resolution: 2.7 Å | in vitro · -173.15 °C · pH 6 · ligands NAG, ZN Structure of SARS-CoV-2 Gamma variant receptor-binding domain complexed with high affinity human ACE2 mutant (T27F,R273Q) · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-7WPA-2 RCSB PDB | cryoem | resolution: 2.77 Å | in vitro · ligands CL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron Variant SPIKE trimer complexed with ACE2 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7V85-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form · Angiotensin-converting enzyme 2,Green fluorescent protein (chains F,H) | unmapped |
| EV-PDB-7V81-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form · Angiotensin-converting enzyme 2,Green fluorescent protein (chains D,E) | unmapped |
| EV-PDB-7V7Z-2 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form · Angiotensin-converting enzyme 2,Green fluorescent protein (chains D,E,F) | unmapped |
| EV-PDB-7UFL-1 RCSB PDB | xray | resolution: 2.84 Å | in vitro · -173.15 °C · ligands CL, EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric omicron RBD (strain BA.2) complexed with chimeric mouse ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-7WPB-2 RCSB PDB | cryoem | resolution: 2.79 Å | in vitro · ligands CL, NAG, ZN SARS-CoV-2 Omicron Variant RBD complexed with ACE2 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7WPC-2 RCSB PDB | cryoem | resolution: 2.57 Å | in vitro · ligands CL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose The second RBD of SARS-CoV-2 Omicron Variant in complexed with RBD-ACE2 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7WS8-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7WS9-2 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7WSA-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands NAG Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7WVP-1 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C2 state · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7WVQ-2 RCSB PDB | cryoem | resolution: 4.04 Å | in vitro Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C3 state · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7XAZ-1 RCSB PDB | xray | resolution: 3 Å | in vitro · -173.15 °C · pH 7 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of Omicron BA.1.1 RBD complexed with hACE2 · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7XB0-1 RCSB PDB | xray | resolution: 2.9 Å | in vitro · -173.15 °C · pH 5.5 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of Omicron BA.2 RBD complexed with hACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7XB1-1 RCSB PDB | xray | resolution: 2.7 Å | in vitro · -173.15 °C · pH 7 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of Omicron BA.3 RBD complexed with hACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7XBF-1 RCSB PDB | xray | resolution: 3.51 Å | in vitro · -173.15 °C · ligands NAG, ZN The complex structure of RshSTT182/200 RBD-insert2 bound to human ACE2 · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7XBG-1 RCSB PDB | xray | resolution: 3.37 Å | in vitro · -173.15 °C · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose The crystal structure of RshSTT182/200 RBD-insert2-T346R-Y496G mutant in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7XBH-2 RCSB PDB | xray | resolution: 3.02 Å | in vitro · -173.15 °C · ligands NAG, ZN The complex structure of RshSTT182/200 RBD bound to human ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7XCH-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (two-RBD-up state) · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7XCI-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with human ACE2 ectodomain (local refinement) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7XCP-1 RCSB PDB | cryoem | resolution: 3.05 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7XID-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron) in complex with PD of ACE2 · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-7XO7-2 RCSB PDB | cryoem | resolution: 3.38 Å | in vitro · ligands CL, NAG, ZN SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two human ACE2 Bound · Angiotensin-converting enzyme 2 (chains E,F) | unmapped |
| EV-PDB-7XO8-2 RCSB PDB | cryoem | resolution: 3.48 Å | in vitro · ligands CL, NAG, ZN SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three human ACE2 Bound · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7XO9-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands CL, NAG, ZN SARS-CoV-2 Omicron BA.2 Variant RBD complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7XWA-1 RCSB PDB | xray | resolution: 3.36 Å | in vitro · -173.15 °C · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BA.4/5 variant spike protein in complex with its receptor ACE2 · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7Y1Y-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron BA.2) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D,F,H) | unmapped |
| EV-PDB-7Y1Z-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron BA.3) in complex with three PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D,F,H) | unmapped |
| EV-PDB-7Y20-2 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron BA.3) in complex with two PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D,F) | unmapped |
| EV-PDB-7Y21-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron BA.5) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D,F,H) | unmapped |
| EV-PDB-7Y75-2 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands 3PH, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SIT1-ACE2-BA.2 RBD · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7Y76-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands 3PH, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SIT1-ACE2-BA.5 RBD · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-7Y9Z-2 RCSB PDB | cryoem | resolution: 2.85 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (one-RBD-up state) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-7YA0-2 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (S-6P-RRAR) · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-7YA1-1 RCSB PDB | cryoem | resolution: 3.11 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7YDI-1 RCSB PDB | cryoem | resolution: 3.98 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7YEG-2 RCSB PDB | cryoem | resolution: 3.73 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2 · Angiotensin-converting enzyme 2 (chains E,J,M) | unmapped |
| EV-PDB-7YHW-1 RCSB PDB | cryoem | resolution: 3.09 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7YJ3-1 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro · ligands NAG, ZN Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7YR2-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands CL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state1) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7YR3-2 RCSB PDB | cryoem | resolution: 3.52 Å | in vitro · ligands CL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state2) · Angiotensin-converting enzyme 2 (chains D,G) | unmapped |
| EV-PDB-7YR4-1 RCSB PDB | cryoem | resolution: 4.12 Å | in vitro SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(interface) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7ZDQ-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-7ZF7-1 RCSB PDB | xray | resolution: 3.46 Å | in vitro · -173.15 °C · ligands NAG, ZN SARS-CoV-2 Omicron BA.2 RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8AQS-2 RCSB PDB | cryoem | resolution: 2.92 Å | in vitro · ligands NAG, ZN BA.4/5 SARS-CoV-2 Spike bound to human ACE2 (local) · Processed angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-8ASY-1 RCSB PDB | xray | resolution: 2.85 Å | in vitro · -173.15 °C · ligands CL, GOL, NAG, PGE SARS-CoV-2 Omicron BA.2.75 RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8B9P-1 RCSB PDB | xray | resolution: 2.11 Å | in vitro · -173.15 °C · pH 4.6 · ligands LFI ACE2 in complex with bicyclic peptide inhibitor · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8BFW-1 RCSB PDB | xray | resolution: 2.33 Å | in vitro · -173.15 °C · pH 4.6 · ligands LFI The structures of Ace2 in complex with bicyclic peptide inhibitor · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8BN1-1 RCSB PDB | xray | resolution: 2.61 Å | in vitro · -173.15 °C · pH 8 · ligands LFI, ZN The structures of Ace2 in complex with bicyclic peptide inhibitor · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8BYJ-1 RCSB PDB | xray | resolution: 2.07 Å | in vitro · -173.15 °C · ligands LFI, NA, ZN The structures of Ace2 in complex with bicyclic peptide inhibitor · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8DF5-3 RCSB PDB | xray | resolution: 2.7 Å | in vitro · -173.15 °C · ligands CL, EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Beta RBD in complex with human ACE2 and S304 Fab and S309 Fab · Angiotensin-converting enzyme 2 (chains E,F) | unmapped |
| EV-PDB-8DLJ-2 RCSB PDB | cryoem | resolution: 2.91 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Alpha (B.1.1.7) spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-8DLK-2 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Alpha (B.1.1.7) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-8DLM-2 RCSB PDB | cryoem | resolution: 2.89 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-8DLN-2 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-8DLP-2 RCSB PDB | cryoem | resolution: 2.64 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-8DLQ-2 RCSB PDB | cryoem | resolution: 2.77 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-8DLU-2 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-8DLV-2 RCSB PDB | cryoem | resolution: 3.11 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-8DM6-2 RCSB PDB | cryoem | resolution: 2.77 Å | in vitro · ligands NAG Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8DV2-2 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro · ligands NAG SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to computationally engineered ACE2 mimetic CVD293 · Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion (chains D) | unmapped |
| EV-PDB-8FXB-3 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands NAG, branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 XBB.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8FXC-3 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, ZN, branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8H5C-1 RCSB PDB | xray | resolution: 2.9 Å | in vitro · -173.15 °C · pH 7 · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 Omicron BA.2.75 RBD in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8HRK-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro SARS-CoV-2 Delta S-RBD-ACE2 complex · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8HRL-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro SARS-CoV-2 Delta S-RBD-ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8HRN-1 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro Cryo-EM structure of ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8I91-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands CL, NAG, PRO, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-SIT1 complex bound with proline · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8I92-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands GLN, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-B0AT1 complex bound with glutamine · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8I93-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands MET, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-B0AT1 complex bound with methionine · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8I9B-2 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron BA.2.75) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-8I9C-2 RCSB PDB | cryoem | resolution: 3.85 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron BF.7) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-8I9D-2 RCSB PDB | cryoem | resolution: 3.95 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-ECD (Omicron XBB.1) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-8I9E-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-RBD(Omicron BA.3) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8I9F-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-RBD (Omicron BA.2.75) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8I9G-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-RBD (Omicron BF.7) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8I9H-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose S-RBD (Omicron XBB.1) in complex with PD of ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8IOU-2 RCSB PDB | cryoem | resolution: 3.18 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 XBB.1 spike glycoprotein in complex with ACE2 (1-up state) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8IOV-1 RCSB PDB | cryoem | resolution: 3.29 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 XBB.1 spike RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8JWH-1 RCSB PDB | cryoem | resolution: 3.34 Å | in vitro Cryo-EM structure of apo-state huamn angiotensin-converting enzyme 2 (ACE2) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8JYO-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (2-up state) · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-8JYP-2 RCSB PDB | cryoem | resolution: 3.38 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 XBB.1.5 spike RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8P2Y-1 RCSB PDB | cryoem | resolution: 3.46 Å | in vitro · ligands NAG, NDG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human SIT1:ACE2 complex (closed PD conformation) · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8P2Z-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro · ligands CL, NAG, YCP Structure of human SIT1 bound to L-pipecolate (focussed map / refinement) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8QSQ-2 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro · ligands NAG Locally refined SARS-CoV-2 BA-2.86 Spike receptor binding domain (RBD) complexed with angiotensin converting enzyme 2 (ACE2) · Processed angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-8S9G-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands NAG, branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8SPH-1 RCSB PDB | xray | resolution: 2.71 Å | in vitro · -173.15 °C · pH 8.2 · ligands CL, EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric omicron RBD (strain XBB.1) complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8SPI-1 RCSB PDB | xray | resolution: 3.06 Å | in vitro · -173.15 °C · pH 8.2 · ligands CL, EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric omicron RBD (strain XBB.1.5) complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8TOQ-1 RCSB PDB | xray | resolution: 2.3 Å | in vitro · -173.15 °C · ligands CL, NAG, ZN ACE2-peptide 1 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8TOR-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -173.15 °C · pH 4 · ligands CL, GOL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-peptide 2 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8TOS-1 RCSB PDB | xray | resolution: 2.35 Å | in vitro · -173.15 °C · pH 4 · ligands CL, GOL, NAG, ZN, branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-peptide 6 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8TOT-1 RCSB PDB | xray | resolution: 2.8 Å | in vitro · -173.15 °C · pH 5.5 · ligands CL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-peptide2 complex crystal form 2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8TOU-1 RCSB PDB | xray | resolution: 3.1 Å | in vitro · -173.15 °C · pH 7.5 · ligands CL, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ACE2-peptide 2 complex crystal form 3 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8P31-1 RCSB PDB | cryoem | resolution: 3.24 Å | in vitro · ligands NAG, NDG, YCP, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8P30-1 RCSB PDB | cryoem | resolution: 3.29 Å | in vitro · ligands CL, NAG, NDG, YCP, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8P2X-1 RCSB PDB | cryoem | resolution: 3.59 Å | in vitro · ligands NAG, NDG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human SIT1:ACE2 complex (open PD conformation) · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8P2W-1 RCSB PDB | cryoem | resolution: 3.76 Å | in vitro · ligands NAG Structure of human SIT1 (focussed map / refinement) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8JYN-2 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (1-up state) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8JJE-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, SO4, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose RBD of SARS-CoV2 spike protein with ACE2 decoy · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8IF2-1 RCSB PDB | xray | resolution: 2.78 Å | in vitro · -173.15 °C · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BQ.1.1 variant spike protein in complex with its receptor ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8HRU-1 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro Cryo-EM structure of ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8H06-1 RCSB PDB | cryoem | resolution: 2.66 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with human ACE2 (local refinement) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8E7M-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Structure of the human ACE2 receptor in complex with antibody Fab fragment, 05B04 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8DV1-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to linker variant of affinity matured ACE2 mimetic CVD432 · Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion,Immunoglobulin gamma-1 heavy chain (chains D) | unmapped |
| EV-PDB-8DM5-2 RCSB PDB | cryoem | resolution: 2.51 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-8UZE-1 RCSB PDB | xray | resolution: 3.03 Å | in vitro · -173.15 °C · ligands CL, EDO, NA, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric bat coronavirus BANAL-20-236 RBD complexed with chimeric mouse ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8WLZ-2 RCSB PDB | cryoem | resolution: 4.45 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of the WIV1 S-hACE2 complex · Processed angiotensin-converting enzyme 2 (chains D,G) | unmapped |
| EV-PDB-8WRO-2 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro XBB.1.5.10 spike protein in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8WTJ-2 RCSB PDB | cryoem | resolution: 4.64 Å | in vitro XBB.1.5.70 spike protein in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains E) | unmapped |
| EV-PDB-8XLM-2 RCSB PDB | cryoem | resolution: 3.22 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein in complex with ACE2 (1-up state) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8XLN-1 RCSB PDB | cryoem | resolution: 3.78 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of the SARS-CoV-2 EG.5.1 spike RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8XUY-2 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up state) · Processed angiotensin-converting enzyme 2 (chains D,O) | unmapped |
| EV-PDB-8XUZ-2 RCSB PDB | cryoem | resolution: 3.05 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up and 1-down state) · Processed angiotensin-converting enzyme 2 (chains L) | unmapped |
| EV-PDB-8XV0-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (up state) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XV1-2 RCSB PDB | cryoem | resolution: 3.05 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (down state) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8XVM-2 RCSB PDB | cryoem | resolution: 2.77 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (3-up state) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8XYO-1 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro · ligands NAG, ZN Cryo-EM structure of CX1 receptor binding domain in complex with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XYG-1 RCSB PDB | xray | resolution: 3.64 Å | in vitro · -173.15 °C Crystal structure of SARS-CoV-2 BQ.1.1 RBD and human ACE2 · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8XYE-1 RCSB PDB | xray | resolution: 3.32 Å | in vitro · -173.15 °C · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of SARS-CoV-2 BA.4 RBD and human ACE2 · Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8XY9-1 RCSB PDB | xray | resolution: 3.64 Å | in vitro · -173.15 °C · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of SARS-CoV-2 BF.7 RBD and human ACE2 complex · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8XXW-1 RCSB PDB | cryoem | resolution: 3.03 Å | in vitro · ligands NAG, ZN Fab M2-7 complexed with SARS-Cov2 RBD and human ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XSJ-1 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XSF-1 RCSB PDB | cryoem | resolution: 2.16 Å | in vitro · ligands NAG, ZN SARS-CoV-2 RBD + IMCAS-364 + hACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XNK-1 RCSB PDB | cryoem | resolution: 2.78 Å | in vitro · ligands NAG, ZN Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XNF-1 RCSB PDB | cryoem | resolution: 3.26 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XN5-1 RCSB PDB | cryoem | resolution: 2.87 Å | in vitro · ligands NAG, ZN Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XN3-1 RCSB PDB | cryoem | resolution: 2.64 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XN2-1 RCSB PDB | cryoem | resolution: 2.79 Å | in vitro · ligands NAG, ZN, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8XAL-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with ACE2 · Angiotensin-converting enzyme 2,Green fluorescent protein (Fragment) (chains I,J) | unmapped |
| EV-PDB-8WYH-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro The global map of Omicron Subvariants Spike with ACE2 · Angiotensin-converting enzyme 2 (chains T,X,Z) | unmapped |
| EV-PDB-8WTD-1 RCSB PDB | cryoem | resolution: 3.06 Å | in vitro · ligands NAG XBB.1.5.10 RBD in complex with ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WSR-2 RCSB PDB | cryoem | resolution: 2.99 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose The structure of LS1_RBD/hACE2 protein · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WRM-2 RCSB PDB | cryoem | resolution: 4.34 Å | in vitro XBB.1.5 spike protein in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8WRL-1 RCSB PDB | cryoem | resolution: 3.36 Å | in vitro · ligands NAG XBB.1.5 RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WRH-1 RCSB PDB | cryoem | resolution: 3.08 Å | in vitro · ligands NAG SARS-CoV-2 XBB.1.5.70 in complex with ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WP8-1 RCSB PDB | cryoem | resolution: 2.89 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WM3-2 RCSB PDB | cryoem | resolution: 3.34 Å | in vitro · ligands NAG, TGI, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of ACE2-SIT1 complex with tiagabine · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-8WHZ-1 RCSB PDB | cryoem | resolution: 3.93 Å | in vitro · ligands CL, NAG, ZN BA.2.86 RBD in complex with hACE2 (local refinement) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WHU-2 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands CL, NAG, ZN, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Spike Trimer of BA.2.86 in complex with two hACE2s · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-8WHS-2 RCSB PDB | cryoem | resolution: 3.33 Å | in vitro · ligands CL, NAG, ZN, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Spike Trimer of BA.2.86 in complex with one hACE2 · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8WGW-2 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Local refinement of RBD-ACE2 · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-8WGV-2 RCSB PDB | cryoem | resolution: 2.92 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose BA.2(S375) Spike (S6P)/hACE2 complex · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-8WE4-1 RCSB PDB | cryoem | resolution: 2.91 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WE1-1 RCSB PDB | cryoem | resolution: 2.47 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BF.7 RBD complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WE0-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron XBB RBD complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WDZ-1 RCSB PDB | cryoem | resolution: 2.71 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BQ.1 RBD complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WDY-1 RCSB PDB | cryoem | resolution: 2.69 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BQ.1.1 RBD complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8WDS-1 RCSB PDB | xray | resolution: 3.4 Å | in vitro · 17.85 °C · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of BF.7 RBD complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8WDR-1 RCSB PDB | xray | resolution: 3.47 Å | in vitro · -173.15 °C · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of BQ.1.1 RBD complexed with human ACE2 · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-8WBZ-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands NAG, XF0, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of ACE2-B0AT1 complex with JX225 · Angiotensin-converting enzyme 2 (chains B,C) | unmapped |
| EV-PDB-8WBY-2 RCSB PDB | cryoem | resolution: 3.18 Å | in vitro · ligands NAG, WM8, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of ACE2-B0AT1 complex with JX98 · Angiotensin-converting enzyme 2 (chains B,C) | unmapped |
| EV-PDB-8VQR-1 RCSB PDB | xray | resolution: 2.565 Å | in vitro · -173.15 °C · ligands CL, EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric SARS-CoV-2 RBD complexed with chimeric raccoon dog ACE2 · Angiotensin-converting enzyme,Processed angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8VKP-2 RCSB PDB | cryoem | resolution: 2.77 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) · Processed angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8VKO-2 RCSB PDB | cryoem | resolution: 2.68 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-8UZF-1 RCSB PDB | xray | resolution: 3.283 Å | in vitro · -173.15 °C · ligands CL, EDO, NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of chimeric RaTG13 RBD complexed with chimeric mouse ACE2 · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-8Y16-1 RCSB PDB | cryoem | resolution: 2.98 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2 · Angiotensin-converting enzyme 2 (chains A,E,F) | unmapped |
| EV-PDB-8Y18-1 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron JN.1 RBD in complex with human ACE2 (local refinement from the spike protein) · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8Z4X-2 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 D614G S with two ACE2 receptors binding (RB2) in prefusion conformation · Angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-8Z64-2 RCSB PDB | cryoem | resolution: 3.53 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 D614G S with three ACE2 receptors binding (RB3) in prefusion conformation (focused refinement of NTD-SD1-RBD-ACE2) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8Z6A-2 RCSB PDB | cryoem | resolution: 2.99 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 D614G S with three ACE2 receptors binding (RB3) in prefusion conformation · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-8Z7B-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of NTD-SD1-RBD-ACE2) · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8Z7P-1 RCSB PDB | cryoem | resolution: 3.45 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9BNG-1 RCSB PDB | cryoem | resolution: 3.73 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 spike HexaPro protein in complex with T18A trimeric antagonist · Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2 (chains A,C,E) | unmapped |
| EV-PDB-9IU1-1 RCSB PDB | cryoem | resolution: 4.3 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of SARS-CoV-2 JN.1 spike RBD in complex with ACE2 (up state) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9IUP-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG KP.3 RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9IUU-1 RCSB PDB | cryoem | resolution: 3.29 Å | in vitro · ligands CL, NAG, ZN JN.1 RBD with Q493E in complex with ACE2 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9JJ6-2 RCSB PDB | cryoem | resolution: 2.94 Å | in vitro · ligands NAG BtHKU5-CoV-2-441 Spike RBD domain binding to hACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9KXW-2 RCSB PDB | cryoem | resolution: 2.66 Å | in vitro · ligands NA, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human B0AT1-ACE2 · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-9KXY-2 RCSB PDB | cryoem | resolution: 2.82 Å | in vitro · ligands A1L6U, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human B0AT1-ACE2 complex with compound1 · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-9LDJ-4 RCSB PDB | cryoem | resolution: 6.21 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 wide-type S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9UE7-1 RCSB PDB | cryoem | resolution: 2.27 Å | in vitro Cryo-EM structure of SARS-CoV-2 KP.2 spike in complex with ACE2 · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9XHZ-2 RCSB PDB | cryoem | resolution: 5.28 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C092 Fab and ACE2 (2 RBD up) · Processed angiotensin-converting enzyme 2 (chains D,E) | unmapped |
| EV-PDB-9XI0-4 RCSB PDB | cryoem | resolution: 3.98 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C092 Fab and ACE2 (3 RBD up) · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9XHY-1 RCSB PDB | cryoem | resolution: 3.84 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with C092 Fab and ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9VLT-2 RCSB PDB | cryoem | resolution: 5.65 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab · Angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9VA2-1 RCSB PDB | cryoem | resolution: 2.87 Å | in vitro · ligands NAG, PHE, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of the ACE2-B0AT1 bound with Phenylalanine · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-9VA1-1 RCSB PDB | cryoem | resolution: 3.24 Å | in vitro · ligands TRP Structure of the ACE2-B0AT1 bound with tryptophan · Angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-9UE6-2 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Cryo-EM structure of SARS-CoV-2 KP.2 spike RBD in complex with ACE2 · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-9U4O-1 RCSB PDB | cryoem | resolution: 2.77 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM Structure of Human ACE2 Complexed with RacCS20637 RBD · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9SPA-1 RCSB PDB | xray | resolution: 1.79 Å | in vitro · -173.15 °C · pH 7 · ligands MLA, ZN Apo ACE2 extracellular domain · Processed angiotensin-converting enzyme 2 (chains C) | unmapped |
| EV-PDB-9RVT-1 RCSB PDB | xray | resolution: 2.39 Å | in vitro · -173.15 °C · pH 7 ACE2 extracellular domain in complex with the macrocyclic peptide GR1.4 · Processed angiotensin-converting enzyme 2 (chains A,B,D,G) | unmapped |
| EV-PDB-9RVA-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -173.15 °C · pH 7.5 · ligands 2PE, CL, EDO, IPA, NA, NAG, SO4, ZN Crystal structure of the extracellular part of human ACE2 in complex with the macrocyclic peptide WJL-63 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9R19-1 RCSB PDB | xray | resolution: 2.69 Å | in vitro · -173.15 °C · pH 7.5 · ligands CL, NAG Crystal structure of human ACE2 in complex with VHH B07 and VHH B10 · Processed angiotensin-converting enzyme 2 (chains A,B,C) | unmapped |
| EV-PDB-9KY1-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human B0AT1-ACE2 complex with compound1 · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-9KY0-2 RCSB PDB | cryoem | resolution: 2.68 Å | in vitro · ligands A1L6W, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human B0AT1-ACE2 complex with compound3 · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-9KXZ-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands A1L6V, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human B0AT1-ACE2 complex with compound1 · Angiotensin-converting enzyme 2 (chains B,D) | unmapped |
| EV-PDB-9KXV-2 RCSB PDB | cryoem | resolution: 2.71 Å | in vitro · ligands A1L6W, NAG Structure of human B0AT1-ACE2 complex with compound3 · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-9KXU-2 RCSB PDB | cryoem | resolution: 2.87 Å | in vitro · ligands A1L6V, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human B0AT1-ACE2 complex with compound 2 · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-9KXT-2 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro · ligands A1L6U, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Structure of human B0AT1-ACE2 complex with compound1 · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-9J62-1 RCSB PDB | cryoem | resolution: 2.76 Å | in vitro · ligands NAG, ZN Cryo-EM structure of Bat SARS-like coronavirus Khosta-2 spike protein in complex with human ACE2 (local refined) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9IUQ-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands NAG KP.2 RBD in complex with ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9FMM-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · pH 5.5 · ligands A1IDX, CL, EDO, NA, NAG, ZN Structure of human ACE2 in complex with a fluorinated small molecule inhibitor · Angiotensin-converting enzyme 2 (chains A,B) | unmapped |
| EV-PDB-9ELF-1 RCSB PDB | cryoem | resolution: 2.88 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 spike protein in complex with human ACE2 · Processed angiotensin-converting enzyme 2 (chains A,C) | unmapped |
| EV-PDB-9ELE-1 RCSB PDB | cryoem | resolution: 3.16 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 RBD in complex with human ACE2 (local refinement of RBD and hACE2) · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9BNF-1 RCSB PDB | cryoem | resolution: 3.33 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 spike HexaPro protein in complex with T5A trimeric antagonist · Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2 (chains A,C,E) | unmapped |
| EV-PDB-9BNE-1 RCSB PDB | cryoem | resolution: 3.43 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 spike HexaPro protein in complex with T3A trimeric antagonist · Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2 (chains A,C,E) | unmapped |
| EV-PDB-9BND-1 RCSB PDB | cryoem | resolution: 3.19 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 spike HexaPro protein in complex with T0A trimeric antagonist · Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2 (chains A,C,E) | unmapped |
| EV-PDB-8ZBQ-1 RCSB PDB | cryoem | resolution: 3.03 Å | in vitro Local map of Omicron Subvariant JN.1 RBD with ACE2 · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8Z3W-2 RCSB PDB | cryoem | resolution: 3.45 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 D614G S with one ACE2 receptor binding (RB1) in prefusion conformation · Angiotensin-converting enzyme 2 (chains D) | unmapped |
| EV-PDB-8YZJ-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro The structure of Banal-52 RBD and hACE2 complex · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-8YZE-2 RCSB PDB | cryoem | resolution: 3.06 Å | in vitro The JN.1 spike protein (S) in complex with ACE2. · Angiotensin-converting enzyme 2 (chains G,H,I) | unmapped |
| EV-PDB-8YZD-2 RCSB PDB | cryoem | resolution: 3.07 Å | in vitro Structure of JN.1 RBD protein in complex with ACE2. · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-8YZC-2 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Structure of BA.2.86 spike protein in complex with ACE2. · Angiotensin-converting enzyme 2 (chains G,H,I) | unmapped |
| EV-PDB-8YZB-2 RCSB PDB | cryoem | resolution: 3.29 Å | in vitro BA.2.86 RBD protein in complex with ACE2. · Angiotensin-converting enzyme 2 (chains B) | unmapped |
| EV-PDB-8Y6A-1 RCSB PDB | cryoem | resolution: 2.72 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 and S309 Fab · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9XI1-1 RCSB PDB | cryoem | resolution: 2.58 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with C092 Fab and ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9XI2-1 RCSB PDB | cryoem | resolution: 2.83 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with C807 Fab and ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9XI3-1 RCSB PDB | cryoem | resolution: 4.74 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C807 Fab and ACE2 (3 RBD up) · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9XI4-1 RCSB PDB | cryoem | resolution: 2.83 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with BD56-104 Fab and ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9XI5-1 RCSB PDB | cryoem | resolution: 3.06 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with BD56-104 Fab and ACE2 (3 RBD up) · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9XI6-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands NAG, ZN SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with BD56-597 Fab and ACE2 · Processed angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9XI7-2 RCSB PDB | cryoem | resolution: 3.22 Å | in vitro · ligands NAG, ZN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with BD56-597 Fab and ACE2 (3 RBD up) · Processed angiotensin-converting enzyme 2 (chains D,E,F) | unmapped |
| EV-PDB-9YSR-1 RCSB PDB | cryoem | resolution: 3.63 Å | in vitro · ligands NAG Local refinement of hACE2/SARS-CoV-2 BA.3.2.1 spike, conformation 1 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-PDB-9YSS-1 RCSB PDB | cryoem | resolution: 3.67 Å | in vitro · ligands NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Local refinement of hACE2/SARS-CoV-2 LP.8.1 spike, conformation 1 · Angiotensin-converting enzyme 2 (chains A) | unmapped |
| EV-BMRB-34650 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 2.5 NMR structure of human ACE2 21-42 fragment in HFIP/water 50/50 v/v · BMRB data: 13C chemical shifts, 1H chemical shifts | unmapped |
| EV-SASBDB-SASDXW6 SASBDB | saxs_sans | radius_of_gyration: 5.446 nm ± 1.752 | in vitro · 10 °C · pH 8 ACE 2 protein · Angiotensin Converting Enzyme2 | unmapped |
| EV-SASBDB-SASDXX6 SASBDB | saxs_sans | radius_of_gyration: 6.709 nm ± 0.562 | in vitro · 10 °C · pH 8 · ligands partner: Receptor Binding Domain ACE2 RBD Complex · Angiotensin converting Enzyme 2 with Receptor Binding Domain | unmapped |
| EV-SASBDB-SASDYG7 SASBDB | saxs_sans | radius_of_gyration: 4.393 nm ± 0.896 | in vitro · 10 °C · pH 8 · ligands partner: Spike glycoprotein ACE 2 RBD with Umifenovir · Angiotensin-converting enzyme 2 with Spike glycoprotein | unmapped |
| EV-DISPROT-DP02854r001 DisProt | cryoem | disorder_region: 37 residues | in vitro DisProt DP02854: disorder, residues 769-805 · residues 769-805; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion | unmapped |
| EV-AFDB-AF-Q9BYF1-F1 AlphaFold DB | af_prediction | plddt: 90.69 pLDDT | in silico AlphaFold DB prediction AF-Q9BYF1-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-805 | unmapped |
| EV-MDDB-MCV1900002 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with FERR ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900004 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Human Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900013 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with Rhinolophus Affinis ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900014 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with FERR ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900015 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with MACR ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900016 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with Pangolin ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900017 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with PUS ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900018 MDDB | md | trajectory: 196.94 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with SIN1 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900019 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with SIN2 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900020 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with SIN3 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900021 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Bat-SARSr-CoV RATG13 spike receptor binding domain bound with ZIBB ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900022 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with human ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900023 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with MACR ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900024 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with Pangolin ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900025 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with PUS ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900026 MDDB | md | trajectory: 199.56 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with SIN1 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900027 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with SIN2 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900028 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with SIN3 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900029 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS spike receptor binding domain bound with ZIBB ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900030 MDDB | md | trajectory: 192.05 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with human ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900031 MDDB | md | trajectory: 189.97 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with FERR ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900032 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with MACR ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900033 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with Pangolin ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900034 MDDB | md | trajectory: 190.9 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with PUS ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900035 MDDB | md | trajectory: 195.72 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with SIN1 ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900036 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with SIN2 ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900037 MDDB | md | trajectory: 195.56 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with SIN3 ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900038 MDDB | md | trajectory: 196.16 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with ZIBB ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900039 MDDB | md | trajectory: 178.97 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with AFFINIS ACE2 (REAL) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900040 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with human ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900041 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with FERR ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900042 MDDB | md | trajectory: 198.55 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with MACR ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900043 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with Pangolin ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900044 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with PUS ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900045 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with SIN1 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900046 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with SIN2 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900047 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with SIN3 ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900048 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SARS-CoV-2 spike receptor binding domain bound with ZIBB ACE2 · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900054 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C Human Angiotensin-converting enzyme 2 (ACE2), USA · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900055 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C FERR Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900056 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C MACR Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900057 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C PUS Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900058 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SIN1 Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900059 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SIN1 Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900060 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SIN2 Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900061 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C SIN3 Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900062 MDDB | md | trajectory: 200 ns | in silico · 36.85 °C ZIBB Angiotensin-converting enzyme 2 (ACE2) · start 6VW1; force field not stated | unmapped |
| EV-MDDB-MCV1900065 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940402 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (aclidinium) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900066 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986449 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (afeletecan) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900067 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918588 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (amentoflavone) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900068 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10930330 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (azathioprine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900069 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986305 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (barusiban) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900070 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985913 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (bekanamycin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900071 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940311 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (bendamustine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900072 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986801 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (berzosertib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900073 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918574 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (birinapant) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900074 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10921548 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (brequinar) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900075 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986755 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (brigatinib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900076 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10930513 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (bromocriptine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900077 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10930315 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (brompheniramine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900078 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940945 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (bunazosin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900079 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986295 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (capreomycin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900080 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986707 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (ceritinib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900081 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-11040472 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (chloroquine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900082 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10941001 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (cimicoxib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900083 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918446 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (conivaptan) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900084 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985309 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (copanlisib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900085 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985767 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (dabigatran) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900086 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985081 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (dacomitinib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900087 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985418 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (dasatinib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900088 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940955 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (delavirdine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900089 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940322 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (desvenlafaxine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900090 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940392 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (deutivacaftor) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900091 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918477 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (dimenhydrinate) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900092 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10930274 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (disopyramide) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900093 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985120 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (doxazosin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900094 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10941126 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (doxazosin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900095 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986556 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (e7107) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900096 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986407 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (elamipretide) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900097 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986393 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (elbasvir) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900098 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918481 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (eletriptan) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900099 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940915 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (elvitegravir) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900100 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940388 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (fluoxetine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900101 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10930296 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (fluvastatin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900102 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918487 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (gemifloxacin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900103 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985758 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (gentamicin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900104 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985447 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (imatinib) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900105 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986447 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (ipamorelin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900106 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985229 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (kanamycin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900107 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985989 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (KPT-9274) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900108 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10940981 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (lixivaptan) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900109 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10930235 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (mefloquine) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900110 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918449 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (methylnaltrexone) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900111 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10930143 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (methylprednisolone) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900112 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918451 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (metronidazole) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900113 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918469 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (midazolam) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900114 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986091 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (modithromycin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900115 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10986538 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (nafithromycin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900116 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10985237 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (netilmicin) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-MDDB-MCV1900117 MDDB | md | trajectory: 2000 ns | in silico · 36.85 °C DESRES-ANTON-10918458 2 µs simulation of an investigational or FDA approved drug molecule binding to the ectodomain of human ACE2, no water or ions (netupitant) · start 6VW1; Amber ff99SB-ILDN | unmapped |
| EV-SMASH-SMFS-000033 SMASH-BIO | force_spectroscopy | study_record | in vitro Beyond ACE2: unveiling the receptor-mediated endocytic dynamic mechanism of SARS-CoV-2 at the single-particle level. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000109 SMASH-BIO | force_spectroscopy | study_record | in vitro Force-Activated Slip-Catch-Slip Bonds Stabilize Virus Interactions · ACE2; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000114 SMASH-BIO | force_spectroscopy | study_record | in vitro Force-regulated catch bonds and fusion peptide exposure drive coronavirus entry · ACE2; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000124 SMASH-BIO | force_spectroscopy | study_record | in vitro Heparin Modulates SARS-CoV-2 Spike-Platelet Factor 4 Interactions through Concentration-Dependent Interface Remodeling. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-000275 SMASH-BIO | force_spectroscopy | study_record | in vitro Single molecule force spectroscopy for evaluating inhibitors of SARS-CoV-2 variants of concern. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000315 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Switching Spike Plasticity Shapes ACE2 Engagement Across SARS-CoV-2 Variants. · ACE2; afm smfs; experiment class: nucleic_acid_protein_interaction, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000424 SMASH-BIO | force_spectroscopy | study_record | in vitro Direct measurement of SARS-CoV-2 spike RBD binding to integrin αvβ6 by single-molecule force spectroscopy. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000452 SMASH-BIO | force_spectroscopy | study_record | in vitro From Attraction to Repulsion: Omicron-Driven Rewiring of Nanobody Interfaces on the SARS-CoV-2 RBD · ACE2; afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-000517 SMASH-BIO | force_spectroscopy | study_record | in vitro Modulation of SARS-CoV-2 spike binding to ACE2 through conformational selection. · ACE2; magnetic tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000520 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.2 Molecular Insights into the Interaction between CD147 and the SARS-CoV‑2 Spike Protein. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000939 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-Molecule Investigation of the Binding Interface Stability of SARS-CoV-2 Variants with ACE2. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000945 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule force stability of the SARS-CoV-2-ACE2 interface in variants-of-concern. · ACE2; magnetic tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001017 SMASH-BIO | force_spectroscopy | study_record | in vitro Unveiling the Dynamic Mechanism of SARS-CoV-2 Entry Host Cells at the Single-Particle Level. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001020 SMASH-BIO | force_spectroscopy | study_record | in vitro Variant-specific interactions at the plasma membrane: Heparan sulfate’s impact on SARS-CoV-2 binding kinetics · ACE2; afm smfs; experiment class: membrane_mechanics, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001302 SMASH-BIO | force_spectroscopy | study_record | in vitro S373P Mutation Stabilizes the Receptor-Binding Domain of the Spike Protein in Omicron and Promotes Binding. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001395-r0 SMASH-BIO | force_spectroscopy | unbinding_force: 26 pN | in vitro · pH 7.2 A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions. · Human ACE2 (GLN18-SER740, C-terminal His-tag), soluble blocking agent (GLN18-SER740); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein; result applies to SARS-CoV-1 RBD:ACE2 fusion construct | unmapped |
| EV-SMASH-SMFS-001395-r1 SMASH-BIO | force_spectroscopy | unbinding_force: 57 pN | in vitro · pH 7.2 A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions. · Human ACE2 (GLN18-SER740, C-terminal His-tag), soluble blocking agent (GLN18-SER740); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein; result applies to SARS-CoV-2 RBD:ACE2 fusion construct | unmapped |
| EV-SMASH-SMFS-001395-r2 SMASH-BIO | force_spectroscopy | unfolding_force: 40 pN | in vitro · pH 7.2 A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions. · Human ACE2 (GLN18-SER740, C-terminal His-tag), soluble blocking agent (GLN18-SER740); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein; result applies to ACE2 domain | unmapped |
| EV-SMASH-SMFS-001395-r3 SMASH-BIO | force_spectroscopy | contour_length_increment: 53 nm | in vitro · pH 7.2 A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions. · Human ACE2 (GLN18-SER740, C-terminal His-tag), soluble blocking agent (GLN18-SER740); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein; result applies to SARS-CoV RBD:ACE2 construct with 31 nm (85 aa) linker | unmapped |
| EV-SMASH-SMFS-001395-r4 SMASH-BIO | force_spectroscopy | contour_length_increment: 66 nm | in vitro · pH 7.2 A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions. · Human ACE2 (GLN18-SER740, C-terminal His-tag), soluble blocking agent (GLN18-SER740); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein; result applies to SARS-CoV RBD:ACE2 construct with 42 nm (115 aa) linker | unmapped |
| EV-SMASH-SMFS-001395-r5 SMASH-BIO | force_spectroscopy | rupture_force: 1500 pN | in vitro · pH 7.2 A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions. · Human ACE2 (GLN18-SER740, C-terminal His-tag), soluble blocking agent (GLN18-SER740); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein; result applies to ClfA:Fg-gamma anchoring handle | unmapped |
| EV-SMASH-SMFS-001661 SMASH-BIO | force_spectroscopy | study_record | in vitro Pathogen-Host Adhesion between SARS-CoV-2 Spike Proteins from Different Variants and Human ACE2 Probed at Single-Molecule and Single-Cell Levels · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001662 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Pathogen-host adhesion between SARS-CoV-2 spike proteins from different variants and human ACE2 studied at single-molecule and single-cell levels. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001699 SMASH-BIO | force_spectroscopy | study_record | in vitro S373P Mutation Stabilizes the Receptor-binding Domain of Spike Protein in Omicron and Promotes Binding · ACE2; afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001742 SMASH-BIO | force_spectroscopy | study_record | in vitro Supported Natural Membranes on Microspheres for Protein-Protein Interaction Studies. · ACE2; optical tweezers; experiment class: membrane_mechanics, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001799 SMASH-BIO | force_spectroscopy | study_record | in vitro A Tethered Ligand Assay to Probe SARS-CoV-2:ACE2 Interactions · ACE2; magnetic tweezers; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001803 SMASH-BIO | force_spectroscopy | study_record | in vitro A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo · ACE2; afm smfs; experiment class: receptor_ligand_adhesion, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-001832 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Biomechanical characterization of SARS-CoV-2 spike RBD and human ACE2 protein-protein interaction. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001909 SMASH-BIO | force_spectroscopy | study_record | in vitro Endothelial glycocalyx shields the interaction of SARS-CoV-2 spike protein with ACE2 receptors. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-002035 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2. · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002217 SMASH-BIO | force_spectroscopy | study_record | in vitro A Tethered Ligand Assay to Probe the SARS-CoV-2 ACE2 Interaction under Constant Force · ACE2; magnetic tweezers; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002258 SMASH-BIO | force_spectroscopy | study_record | in vitro Biomechanical Characterization of SARS-CoV-2 Spike RBD and Human ACE2 Protein-Protein Interaction · ACE2; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
Conflicts
No conflicts found among comparable evidence.
494 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.