DNA repair protein RAD51 homolog 1
UniProt Q06609 · gene RAD51 · Homo sapiens · 339 residues
127evidence items
0mapped to a state
0states
7techniques
6sources
0conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | nmr_structure | nmr_shifts | saxs_sans | force_spectroscopy | af_prediction | Total |
|---|---|---|---|---|---|---|---|---|---|
| No states defined yet. | |||||||||
Unmapped evidence: 127 of 127 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 2 | 0 |
| DisProt | 6 | 0 |
| RCSB PDB | 55 | 0 |
| SASBDB | 38 | 0 |
| SMASH-BIO | 25 | 0 |
Structure
No state models are exported for this protein yet. Observed states export the representative PDB entry; inferred states need fitted models, not yet built.
States and transitions
No states defined.
| State | Basis | Parent | Description |
|---|
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-1B22-1 RCSB PDB | nmr_structure | structure | in vitro · 29.85 °C · pH 6.5 RAD51 (N-TERMINAL DOMAIN) · DNA REPAIR PROTEIN RAD51 (chains A) | unmapped |
| EV-PDB-1N0W-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 7.2 · ligands CL, EDO, MG Crystal structure of a RAD51-BRCA2 BRC repeat complex · DNA repair protein RAD51 homolog 1 (chains A) | unmapped |
| EV-PDB-5H1B-1 RCSB PDB | cryoem | resolution: 4.4 Å | in vitro · ligands ANP, MG Human RAD51 presynaptic complex · DNA repair protein RAD51 homolog 1 (chains A,B,C) | unmapped |
| EV-PDB-5H1C-1 RCSB PDB | cryoem | resolution: 4.5 Å | in vitro · ligands ANP, MG Human RAD51 post-synaptic complexes · DNA repair protein RAD51 homolog 1 (chains A,B,C) | unmapped |
| EV-PDB-5JZC-1 RCSB PDB | cryoem | resolution: 4.2 Å | in vitro helical filament · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G) | unmapped |
| EV-PDB-5NP7-1 RCSB PDB | cryoem | resolution: 4.2 Å | in vitro · ligands ANP CryoEM structure of Human Rad51 on single-stranded DNA to 4.2A resolution. · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G) | unmapped |
| EV-PDB-5NWL-1 RCSB PDB | xray | resolution: 3.93 Å | in vitro · -173.15 °C · ligands ATP, MG Crystal structure of a human RAD51-ATP filament. · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N) | unmapped |
| EV-PDB-7C9A-1 RCSB PDB | cryoem | resolution: 3.43 Å | in vitro · ligands ANP, CA Human RAD51 post-synaptic complexes mutant (V273P, D274G) · DNA repair protein RAD51 homolog 1 (chains A,B,C) | unmapped |
| EV-PDB-7EJC-2 RCSB PDB | cryoem | resolution: 2.97 Å | in vitro · ligands ANP, J46, MG human RAD51 presynaptic complex · DNA repair protein RAD51 homolog 1 (chains A,B,C) | unmapped |
| EV-PDB-7EJE-1 RCSB PDB | cryoem | resolution: 3.98 Å | in vitro · ligands ANP, MG human RAD51 post-synaptic complex · DNA repair protein RAD51 homolog 1 (chains A,B,C) | unmapped |
| EV-PDB-8BQ2-1 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro · ligands ATP, CA CryoEM structure of the pre-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+ · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I) | unmapped |
| EV-PDB-8BR2-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands ATP, CA CryoEM structure of the post-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+ · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-8BSC-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro · ligands ADP, CA CryoEM structure of the RAD51 nucleoprotein filament in the presence of ADP and Ca2+ · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G) | unmapped |
| EV-PDB-8C3J-1 RCSB PDB | xray | resolution: 3.02 Å | in vitro · -173.15 °C · ligands TKI Stapled peptide SP2 in complex with humanised RadA mutant HumRadA22 · DNA repair and recombination protein RadA (chains A,B) | unmapped |
| EV-PDB-8GYK-1 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro · ligands ADP, MG CryoEM structure of the RAD51_ADP filament · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H) | unmapped |
| EV-PDB-8JND-7 RCSB PDB | cryoem | resolution: 3.66 Å | in vitro The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding · DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P,Q,R,S) | unmapped |
| EV-PDB-8JNE-7 RCSB PDB | cryoem | resolution: 4.68 Å | in vitro The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome without the linker DNA binding · DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P,Q,R,S,T) | unmapped |
| EV-PDB-8JNF-7 RCSB PDB | cryoem | resolution: 6.91 Å | in vitro The cryo-EM structure of the RAD51 filament bound to the nucleosome · DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P) | unmapped |
| EV-PDB-8PBC-1 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro · ligands ATP, CA RAD51 filament on ssDNA bound by the BRCA2 c-terminus · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I,J,K) | unmapped |
| EV-PDB-8PBD-1 RCSB PDB | cryoem | resolution: 2.83 Å | in vitro · ligands ATP, CA RAD51 filament on dsDNA bound by the BRCA2 c-terminus · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-8R64-2 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands ADP, ATP, MG Cryo-EM structure of the FIGNL1 AAA hexamer bound to RAD51 · DNA repair protein RAD51 homolog 1 (chains G) | unmapped |
| EV-PDB-8RCD-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands ATP, CA RAD51 nucleoprotein filament on abasic single-stranded DNA · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H) | unmapped |
| EV-PDB-8RCF-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands ATP, CA RAD51 nucleoprotein filament on double-stranded abasic DNA · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H) | unmapped |
| EV-PDB-8UVW-1 RCSB PDB | xray | resolution: 2.73 Å | in vitro · -173.15 °C · ligands ADP, BEF, EDO Crystal structure of RAD51-BRCA2 Cter complex · Breast cancer type 2 susceptibility protein, DNA repair protein RAD51 homolog 1 fusion (chains B) | unmapped |
| EV-PDB-8UVW-2 RCSB PDB | xray | resolution: 2.73 Å | in vitro · -173.15 °C · ligands ADP, BEF, EDO Crystal structure of RAD51-BRCA2 Cter complex · DNA repair protein RAD51 homolog 1,Breast cancer type 2 susceptibility protein (chains D) | unmapped |
| EV-PDB-8XBT-7 RCSB PDB | cryoem | resolution: 4.12 Å | in vitro The cryo-EM structure of the octameric RAD51 ring bound to the nucleosome with the linker DNA binding · DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P,Q,R) | unmapped |
| EV-PDB-8XBU-7 RCSB PDB | cryoem | resolution: 4.24 Å | in vitro The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding · DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P,Q,R,S,T) | unmapped |
| EV-PDB-8XBV-3 RCSB PDB | cryoem | resolution: 7.61 Å | in vitro The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the sticky end of the nucleosome · DNA repair protein RAD51 homolog 1 (chains K,L) | unmapped |
| EV-PDB-8XBW-5 RCSB PDB | cryoem | resolution: 2.89 Å | in vitro The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome · DNA repair protein RAD51 homolog 1 (chains L) | unmapped |
| EV-PDB-8XBX-3 RCSB PDB | cryoem | resolution: 4.36 Å | in vitro The cryo-EM structure of the RAD51 L2 loop bound to the linker DNA with the blunt end of the nucleosome · DNA repair protein RAD51 homolog 1 (chains K,L,M) | unmapped |
| EV-PDB-8XBY-3 RCSB PDB | cryoem | resolution: 7.8 Å | in vitro The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the blunt end of the nucleosome · DNA repair protein RAD51 homolog 1 (chains K,L,M) | unmapped |
| EV-PDB-9I62-1 RCSB PDB | cryoem | resolution: 2.64 Å | in vitro · ligands ATP, CA CryoEM structure of a RAD51 D-loop · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I) | unmapped |
| EV-PDB-9OMY-1 RCSB PDB | cryoem | resolution: 3.25 Å | in vitro · ligands ANP Cryo-EM structure of an octameric RAD51-XRCC3-RAD51C (RAD51-X3C) complex · DNA repair protein RAD51 homolog 1 (chains A,B,D,E) | unmapped |
| EV-PDB-9OMZ-4 RCSB PDB | cryoem | resolution: 3.51 Å | in vitro · ligands ANP Cryo-EM structure of a pentameric RAD51-XRCC3-RAD51C-RAD51D-XRCC2 (51-X3CDX2) complex. · DNA repair protein RAD51 homolog 1 (chains B) | unmapped |
| EV-PDB-9Q23-3 RCSB PDB | cryoem | resolution: 2.84 Å | in vitro · ligands ADP, ATP, MG DX2-CX3-RAD51 structure in the intermediate state · DNA repair protein RAD51 homolog 1 (chains G,I) | unmapped |
| EV-PDB-9Q25-3 RCSB PDB | cryoem | resolution: 3.24 Å | in vitro · ligands ADP, ATP, MG DX2-CX3-RAD51 in the closed state · DNA repair protein RAD51 homolog 1 (chains G) | unmapped |
| EV-PDB-9Q28-3 RCSB PDB | cryoem | resolution: 2.84 Å | in vitro · ligands ADP, ATP, MG DX2-CX3-RAD51 in the active state · DNA repair protein RAD51 homolog 1 (chains G,I) | unmapped |
| EV-PDB-9Q29-3 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro · ligands ADP, ATP, CA DX2-CX3 structure capping RAD51 filament · DNA repair protein RAD51 homolog 1 (chains G,I,J,K,L) | unmapped |
| EV-PDB-9Q2A-4 RCSB PDB | cryoem | resolution: 2.67 Å | in vitro · ligands ADP, ATP, MG BCDX2-CX3-RAD51-RAD51-ssDNA supercomplex · DNA repair protein RAD51 homolog 1 (chains G,I) | unmapped |
| EV-PDB-9Q2B-3 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands ADP, ATP, MG DX2-CX3-RAD51 bound to DNA bubble · DNA repair protein RAD51 homolog 1 (chains G,I) | unmapped |
| EV-PDB-9QN8-1 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro · ligands ATP, CA, K RAD51 filament in complex with calcium and ATP bound by the RAD51AP1 C-terminus · DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K) | unmapped |
| EV-PDB-9QNA-1 RCSB PDB | cryoem | resolution: 3.26 Å | in vitro · ligands ATP, K, MG RAD51 filament in complex with magnesium and ATP · DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K) | unmapped |
| EV-PDB-9QNB-1 RCSB PDB | cryoem | resolution: 3.63 Å | in vitro · ligands ADP, K, MG RAD51 filament in complex with magnesium and ADP · DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K) | unmapped |
| EV-PDB-9QNC-1 RCSB PDB | cryoem | resolution: 2.98 Å | in vitro · ligands ATP, K, MG RAD51 filament in complex with magnesium and ATP bound by the RAD51AP1 C-terminus · DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K) | unmapped |
| EV-PDB-9SRZ-2 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro · ligands ATP, CA RAD51-ssDNA filament in complex with calcium and ATP bound by the RAD54B N-terminus · DNA repair protein RAD51 homolog 1 (chains I,J,K,L,M,N) | unmapped |
| EV-PDB-9SSL-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands ATP, K, MG RAD51-ssDNA filament in complex with magnesium and ATP bound by the RAD54B N-terminus (peptide) · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-9SVX-6 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro · ligands ADP, ATP, CA, MG XRCC3-RAD51C-RAD51D-XRCC2 (XRCC3 complex) capping a RAD51 filament on single stranded DNA · DNA repair protein RAD51 homolog 1 (chains E,F,G,H,I) | unmapped |
| EV-PDB-9SVY-7 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands ADP, ATP, CA, MG XRCC3-RAD51C-RAD51D-XRCC2 (XRCC3 complex) capping a RAD51 filament on partially duplex DNA · DNA repair protein RAD51 homolog 1 (chains E,F,G,H,I,J,K) | unmapped |
| EV-PDB-9SW0-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands ADP, ATP, CA, MG XRCC3-RAD51C-RAD51D-XRCC2 (XRCC3 complex) capping a RAD51 filament on a D-loop intermediate · DNA repair protein RAD51 homolog 1 (chains E,F,G,H,I,J,K) | unmapped |
| EV-PDB-9TRL-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands ATP, K, MG RAD51-ssDNA filament in complex with magnesium and ATP bound by the RAD54B N-terminus (beta-barrel) · DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-9TRM-5 RCSB PDB | cryoem | resolution: 2.4 Å | in vitro · ligands ATP, CA RAD51-dsDNA filament in complex with calcium and ATP bound by the RAD54B N-terminus · DNA repair protein RAD51 homolog 1 (chains I,J,K,L,M,N) | unmapped |
| EV-PDB-9ZZR-8 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro · ligands ANP Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex · DNA repair protein RAD51 homolog 1 (chains F) | unmapped |
| EV-PDB-9ZZR-2 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro · ligands ANP Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex · DNA repair protein RAD51 homolog 1 (chains E,K,O,W) | unmapped |
| EV-PDB-9ZZR-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro · ligands ANP Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex · DNA repair protein RAD51 homolog 1 (chains R,V) | unmapped |
| EV-PDB-9TYY-3 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands ATP, CA RAD51-ssDNA filament in complex with calcium and ATP bound by the RAD54 N-terminus · DNA repair protein RAD51 homolog 1 (chains I,J,K,L,M,N) | unmapped |
| EV-BMRB-11046 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 7.1 hsRad51-bound ssDNA · BMRB data: 1H chemical shifts | unmapped |
| EV-BMRB-4328 BMRB | nmr_shifts | chemical_shift | in vitro · 29.85 °C · pH 6.5 1H, 13C, and 15N Chemical Shift Assignments for Human Rad51(1-114) · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-SASBDB-SASDQ97 SASBDB | saxs_sans | radius_of_gyration: 2.992 nm ± 0.007 | in vitro · 15 °C · pH 8 Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer · DNA repair protein RAD51 homolog 1 (F86E A89E) | unmapped |
| EV-SASBDB-SASDQT9 SASBDB | saxs_sans | radius_of_gyration: 2.857 nm ± 0.048 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein | unmapped |
| EV-SASBDB-SASDQU9 SASBDB | saxs_sans | radius_of_gyration: 3.026 nm ± 0.044 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer · DNA repair protein RAD51 homolog 1 (F86E, A89E, His-Tagged) with Breast cancer type 2 susceptibility protein | unmapped |
| EV-SASBDB-SASDW26 SASBDB | saxs_sans | radius_of_gyration: 2.738 nm ± 0.793 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDW36 SASBDB | saxs_sans | radius_of_gyration: 2.748 nm ± 0.395 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDW46 SASBDB | saxs_sans | radius_of_gyration: 2.764 nm ± 0.219 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDW56 SASBDB | saxs_sans | radius_of_gyration: 2.731 nm ± 0.067 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2) | unmapped |
| EV-SASBDB-SASDW66 SASBDB | saxs_sans | radius_of_gyration: 2.611 nm ± 1.488 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2) | unmapped |
| EV-SASBDB-SASDW76 SASBDB | saxs_sans | radius_of_gyration: 2.663 nm ± 0.727 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2) | unmapped |
| EV-SASBDB-SASDW86 SASBDB | saxs_sans | radius_of_gyration: 2.705 nm ± 0.366 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2) | unmapped |
| EV-SASBDB-SASDW96 SASBDB | saxs_sans | radius_of_gyration: 5.455 nm ± 0.19 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3) | unmapped |
| EV-SASBDB-SASDWA6 SASBDB | saxs_sans | radius_of_gyration: 6.045 nm ± 5.57 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3) | unmapped |
| EV-SASBDB-SASDWB6 SASBDB | saxs_sans | radius_of_gyration: 5.743 nm ± 2.717 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3) | unmapped |
| EV-SASBDB-SASDWC6 SASBDB | saxs_sans | radius_of_gyration: 5.686 nm ± 1.355 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3) | unmapped |
| EV-SASBDB-SASDWD6 SASBDB | saxs_sans | radius_of_gyration: 6.658 nm ± 0.309 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4) | unmapped |
| EV-SASBDB-SASDWE6 SASBDB | saxs_sans | radius_of_gyration: 4.563 nm ± 0.101 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4) | unmapped |
| EV-SASBDB-SASDWF6 SASBDB | saxs_sans | radius_of_gyration: 4.626 nm ± 2.689 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4) | unmapped |
| EV-SASBDB-SASDWG6 SASBDB | saxs_sans | radius_of_gyration: 4.544 nm ± 1.744 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4) | unmapped |
| EV-SASBDB-SASDWH6 SASBDB | saxs_sans | radius_of_gyration: 4.628 nm ± 0.904 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4) | unmapped |
| EV-SASBDB-SASDWJ6 SASBDB | saxs_sans | radius_of_gyration: 5.259 nm ± 0.198 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2) | unmapped |
| EV-SASBDB-SASDWK6 SASBDB | saxs_sans | radius_of_gyration: 5.744 nm ± 5.647 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2) | unmapped |
| EV-SASBDB-SASDWL6 SASBDB | saxs_sans | radius_of_gyration: 5.513 nm ± 2.425 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2) | unmapped |
| EV-SASBDB-SASDWM6 SASBDB | saxs_sans | radius_of_gyration: 5.482 nm ± 1.188 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2) | unmapped |
| EV-SASBDB-SASDWN6 SASBDB | saxs_sans | radius_of_gyration: 7.706 nm ± 0.475 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4) | unmapped |
| EV-SASBDB-SASDWP6 SASBDB | saxs_sans | radius_of_gyration: 8.132 nm ± 5.29 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4) | unmapped |
| EV-SASBDB-SASDWQ6 SASBDB | saxs_sans | radius_of_gyration: 7.622 nm ± 2.151 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4) | unmapped |
| EV-SASBDB-SASDWR6 SASBDB | saxs_sans | radius_of_gyration: 7.72 nm ± 1.158 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4) | unmapped |
| EV-SASBDB-SASDWT5 SASBDB | saxs_sans | radius_of_gyration: 2.03 nm ± 0.026 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDWU5 SASBDB | saxs_sans | radius_of_gyration: 2.011 nm ± 0.564 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDWV5 SASBDB | saxs_sans | radius_of_gyration: 2.062 nm ± 0.299 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDWW5 SASBDB | saxs_sans | radius_of_gyration: 2.079 nm ± 0.164 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDWX5 SASBDB | saxs_sans | radius_of_gyration: 2.124 nm ± 0.117 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDWY5 SASBDB | saxs_sans | radius_of_gyration: 2.783 nm ± 0.035 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDWZ5 SASBDB | saxs_sans | radius_of_gyration: 2.838 nm ± 1.597 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeat 4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4) | unmapped |
| EV-SASBDB-SASDX95 SASBDB | saxs_sans | radius_of_gyration: 6.495 nm ± 2.654 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4) | unmapped |
| EV-SASBDB-SASDXA5 SASBDB | saxs_sans | radius_of_gyration: 6.529 nm ± 1.424 | in vitro · 15 °C · pH 8 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4) | unmapped |
| EV-SASBDB-SASDXB5 SASBDB | saxs_sans | radius_of_gyration: 6.854 nm ± 1.789 | in vitro · 15 °C · pH 7.5 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4) | unmapped |
| EV-SASBDB-SASDXC5 SASBDB | saxs_sans | radius_of_gyration: 6.771 nm ± 0.742 | in vitro · 15 °C · pH 7.5 · ligands partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination · DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4) | unmapped |
| EV-DISPROT-DP01622r001 DisProt | nmr_shifts | disorder_region: 15 residues | in vitro DisProt DP01622: disorder, residues 1-15 · residues 1-15; evidence: proton-based nuclear magnetic resonance evidence used in manual assertion | unmapped |
| EV-DISPROT-DP01622r002 DisProt | nmr_shifts | disorder_region: 29 residues | in vitro DisProt DP01622: disorder, residues 86-114 · residues 86-114; evidence: proton-based nuclear magnetic resonance evidence used in manual assertion | unmapped |
| EV-DISPROT-DP01622r005 DisProt | cryoem | disorder_region: 21 residues | in vitro DisProt DP01622: disorder, residues 1-21 · residues 1-21; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion | unmapped |
| EV-DISPROT-DP01622r006 DisProt | cryoem | disorder_region: 10 residues | in vitro DisProt DP01622: disorder, residues 273-282 · residues 273-282; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion | unmapped |
| EV-DISPROT-DP01622r007 DisProt | cryoem | disorder_region: 10 residues | in vitro DisProt DP01622: disorder to order, residues 273-282 · residues 273-282; evidence: cryogenic electron microscopy evidence used in manual assertion | unmapped |
| EV-DISPROT-DP01622r008 DisProt | cryoem | disorder_region: 10 residues | in vitro DisProt DP01622: order, residues 273-282 · residues 273-282; evidence: cryogenic electron microscopy evidence used in manual assertion | unmapped |
| EV-AFDB-AF-Q06609-F1 AlphaFold DB | af_prediction | plddt: 91.44 pLDDT | in silico AlphaFold DB prediction AF-Q06609-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-339 | unmapped |
| EV-SMASH-SMFS-000637 SMASH-BIO | force_spectroscopy | study_record | in vitro The Eukaryotic homology search complex distorts donor DNA structure to probe for homology · RAD51 recombinase; optical tweezers; experiment class: force_generation_motor, nucleic_acid_mechanics, nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-000984 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA · RAD51 recombinase; optical tweezers; experiment class: nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-000985 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. · RAD51 recombinase; optical tweezers; experiment class: nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-001336 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Structural insights into BCDX2 complex function in homologous recombination. · RAD51 recombinase; hydrodynamic stretching; experiment class: nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-001689 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments. · RAD51 recombinase; hydrodynamic stretching; experiment class: force_generation_motor, nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-002134 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-Stranded DNA Curtains for Single-Molecule Visualization of Rad51-ssDNA Filament Dynamics. · RAD51 recombinase; hydrodynamic stretching; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-002552 SMASH-BIO | force_spectroscopy | study_record | in vitro Structural transitions and mechanochemical coupling in the nucleoprotein filament explain homology selectivity and Rad51 protein cooperativity in cellular DNA repair. · RAD51 recombinase; magnetic tweezers; experiment class: nucleic_acid_protein_interaction, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002750 SMASH-BIO | force_spectroscopy | study_record | in vitro Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects. · RAD51 recombinase; optical tweezers; experiment class: translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-002903 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Single-molecule visualization of human BLM helicase as it acts upon double- and single-stranded DNA substrates. · RAD51 recombinase; hydrodynamic stretching; experiment class: force_generation_motor, nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-003165-r0 SMASH-BIO | force_spectroscopy | step_size: 28 nm | in vitro Long repeating (TTAGGG) n single-stranded DNA self-condenses into compact beaded filaments stabilized by G-quadruplex formation. · RAD51 recombinase; magnetic tweezers; experiment class: nucleic_acid_protein_interaction, translation_transcription_replication, unfolding_nucleic_acid | unmapped |
| EV-SMASH-SMFS-003393 SMASH-BIO | force_spectroscopy | study_record | in vitro A time for promiscuity in a eukaryotic recombinase. · RAD51 recombinase; hydrodynamic stretching; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-003541 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.6 Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination. · RAD51 recombinase; optical tweezers; experiment class: nucleic_acid_mechanics, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-003684 SMASH-BIO | force_spectroscopy | study_record | in vitro Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases. · RAD51 recombinase; hydrodynamic stretching; experiment class: force_generation_motor, nucleic_acid_protein_interaction, receptor_ligand_adhesion, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-003708 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 Single-Stranded DNA Curtains for Studying Homologous Recombination. · RAD51 recombinase; hydrodynamic stretching; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-004106 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 Visualizing recombination intermediates with single-stranded DNA curtains. · RAD51 recombinase; hydrodynamic stretching; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-004756 SMASH-BIO | force_spectroscopy | study_record | in vitro Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution. · RAD51 recombinase; optical tweezers; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-005049 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Structural and torsional properties of the RAD51-dsDNA nucleoprotein filament. · RAD51 recombinase; magnetic tweezers; experiment class: nucleic_acid_mechanics, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-005349 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule views of protein movement on single-stranded DNA. · RAD51 recombinase; magnetic tweezers; experiment class: force_generation_motor, nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-005361 SMASH-BIO | force_spectroscopy | study_record | in vitro Tension induces a base-paired overstretched DNA conformation. · RAD51 recombinase; optical tweezers; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-005810 SMASH-BIO | force_spectroscopy | study_record | in vitro Hop2-Mnd1 condenses DNA to stimulate the synapsis phase of DNA strand exchange. · RAD51 recombinase; optical tweezers; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-006016 SMASH-BIO | force_spectroscopy | study_record | in vitro Counting RAD51 proteins disassembling from nucleoprotein filaments under tension. · RAD51 recombinase; optical tweezers; experiment class: force_generation_polymerization, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-006680 SMASH-BIO | force_spectroscopy | study_record | in vitro Rad54 oligomers translocate and cross-bridge double-stranded DNA to stimulate synapsis. · RAD51 recombinase; optical tweezers; experiment class: force_generation_motor, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-006782 SMASH-BIO | force_spectroscopy | study_record | in vitro Dissecting elastic heterogeneity along DNA molecules coated partly with Rad51 using concurrent fluorescence microscopy and optical tweezers. · RAD51 recombinase; optical tweezers; experiment class: nucleic_acid_mechanics, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-006932 SMASH-BIO | force_spectroscopy | study_record | in vitro Visualizing the assembly of human Rad51 filaments on double-stranded DNA. · RAD51 recombinase; hydrodynamic stretching; experiment class: membrane_mechanics, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-006997 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function. · RAD51 recombinase; magnetic tweezers; experiment class: nucleic_acid_protein_interaction | unmapped |
Conflicts
No conflicts found among comparable evidence.
89 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.