Alpha-synuclein
UniProt P37840 · gene SNCA · Homo sapiens · 140 residues
346evidence items
262mapped to a state
3states
14techniques
6sources
33conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | microed | nmr_structure | nmr_dynamics | nmr_shifts | saxs_sans | epr_deer | cd | ftir_raman | force_spectroscopy | gel_electrophoresis | integrative | af_prediction | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| disordered monomer aS-disordered | inferred | · | · | · | · | proc 2 | proc 27 | proc 11 | rep 1 | rep 4 | rep 1 | · | rep 1 | proc 1 | · | 48 |
| helical, micelle-bound aS-micelle-helix | observed | · | · | · | proc 2 | · | proc 1 | · | · | · | · | · | · | · | · | 3 |
| fibril aS-fibril | observed | proc 3 | proc 204 | proc 1 | proc 3 | · | · | · | · | · | · | · | · | · | · | 211 |
Unmapped evidence: 84 of 346 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 47 | 25 |
| DisProt | 15 | 12 |
| RCSB PDB | 253 | 214 |
| SASBDB | 11 | 11 |
| SMASH-BIO | 19 | 0 |
Curated rules applied
as-disprot-disorder: 11 itemsas-fibril-title: 210 itemsas-integrative-monomer: 1 itemsas-micelle-title: 2 itemsas-nmr-monomer: 25 itemsas-saxs-monomer: 11 items
Structure
Choose a state. Each model is badged observed or inferred; assumptions are one click away.
States and transitions
| State | Basis | Parent | Description |
|---|---|---|---|
| disordered monomer aS-disordered | inferred | — | Intrinsically disordered monomer. No observed structure; ensemble descriptions are not yet ingested.Assumptions (3)
|
| helical, micelle-bound aS-micelle-helix | observed | — | Helical conformation on a membrane-mimetic micelle, as in 1XQ8 (human). |
| fibril aS-fibril | observed | — | Cross-beta fibril, as in 6A6B. Polymorph differences are not separated in the pilot. |
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-2KKW-1 RCSB PDB | nmr_structure | structure | in vitro · 25.05 °C · pH 7.4 SLAS-micelle bound alpha-synuclein · Alpha-synuclein (chains A) | helical, micelle-bound · rule:as-micelle-title · medium Structure titled as micelle-bound. |
| EV-PDB-3Q26-1 RCSB PDB | xray | resolution: 1.54 Å | in vitro · -173.15 °C · pH 8 · ligands GOL, SO4, branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Cyrstal structure of human alpha-synuclein (10-42) fused to maltose binding protein (MBP) · Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A) | unmapped |
| EV-PDB-6CT7-3 RCSB PDB | xray | resolution: 1.903 Å | in vitro · -173.15 °C · pH 8.9 · ligands IPA Fab of anti-a-synuclein antibody BIIB054 in complex with acetylated a-synuclein peptide (1-10) · ACE-MET-ASP-VAL-PHE-MET-LYS-GLY-LEU-SER-LYS (chains S,T) | unmapped |
| EV-PDB-6OSM-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Cryo-EM structure of the N-terminally acetylated C-terminal Alpha-synuclein truncation Ac1-103 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-6XYQ-1 RCSB PDB | cryoem | resolution: 3.09 Å | in vitro Multiple system atrophy Type II-2 alpha-synuclein filament · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6XYP-1 RCSB PDB | cryoem | resolution: 3.29 Å | in vitro Multiple system atrophy Type II-1 alpha-synuclein filament · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6XYO-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro Multiple system atrophy Type I alpha-synuclein filament · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6UFR-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro Structure of recombinantly assembled E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6SSX-1 RCSB PDB | cryoem | resolution: 2.98 Å | in vitro cryo-em structure of alpha-synuclein fibril polymorph 2A · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6SST-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro cryo-em structure of alpha-synuclein fibril polymorph 2B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6RTB-1 RCSB PDB | cryoem | resolution: 3.46 Å | in vitro cryo-em structure of alpha-synuclein fibril polymorph 2B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6RT0-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro cryo-em structure of alpha-synuclein fibril polymorph 2A · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6PES-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro Cryo-EM structure of alpha-synuclein H50Q Wide Fibril · Alpha-synuclein (chains A,B,C,D,E,V,W,X,Y,Z) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6PEO-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Cryo-EM structure of alpha-synuclein H50Q Narrow Fibril · Alpha-synuclein (chains A,B,C,D,E) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6OSL-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Cryo-EM structure of the N-terminally acetylated C-terminal Alpha-synuclein truncation Ac1-122 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-6OSJ-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Cryo-EM structure of the N-terminally acetylated full length alpha-synuclein fibrils (Ac1-140) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6LRQ-1 RCSB PDB | cryoem | resolution: 3.49 Å | in vitro Cryo-EM structure of A53T alpha-synuclein amyloid fibril · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6L4S-1 RCSB PDB | cryoem | resolution: 3.37 Å | in vitro cryo-em structure of alpha-synuclein fiber mutation type E46K · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6L1U-1 RCSB PDB | cryoem | resolution: 3.37 Å | in vitro Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6L1T-1 RCSB PDB | cryoem | resolution: 3.22 Å | in vitro Cryo-EM structure of phosphorylated Tyr39 a-synuclein amyloid fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6I42-2 RCSB PDB | xray | resolution: 1.38 Å | in vitro · -173.15 °C · pH 7 Structure of the alpha-Synuclein PreNAC/Cyclophilin A-complex · Alpha-synuclein (chains B) | unmapped |
| EV-PDB-6H6B-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Structure of alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6CU8-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro Alpha Synuclein fibril formed by full length protein - Twister Polymorph · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6CU7-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro Alpha Synuclein fibril formed by full length protein - Rod Polymorph · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-6A6B-1 RCSB PDB | cryoem | resolution: 3.07 Å | in vitro cryo-em structure of alpha-synuclein fiber · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · curator:draft (unreviewed) · high Cryo-EM fibril; representative for the fibril state. Polymorph not separated. |
| EV-PDB-5CRW-2 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 7.5 Crystal structure of the b'-a' domain of oxidized protein disulfide isomerase complexed with alpha-synuclein peptide (31-41) · Peptide from Alpha-synuclein (chains B) | unmapped |
| EV-PDB-4ZNN-1 RCSB PDB | microed | resolution: 1.41 Å | in vitro · -173.15 °C · pH 7 MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson's disease protein, alpha-synuclein residues 47-56 · Alpha-synuclein (chains A) | unmapped |
| EV-PDB-4RIL-1 RCSB PDB | microed | resolution: 1.43 Å | in vitro · -173.15 °C · pH 4 Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-4RIK-1 RCSB PDB | xray | resolution: 1.854 Å | in vitro · -173.15 °C · pH 4.6 Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-4R0W-1 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 6.5 Vvtgvta, an amyloid forming segment from alpha synuclein, residues 70-76 · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-4R0U-1 RCSB PDB | xray | resolution: 1.38 Å | in vitro · -173.15 °C Tgvtava, an amyloid forming segment from alpha synuclein, residues 72-78 · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-4BXL-2 RCSB PDB | nmr_structure | structure | in vitro · 29.85 °C · pH 7.4 Structure of alpha-synuclein in complex with an engineered binding protein · ALPHA SYNUCLEIN (chains C) | unmapped |
| EV-PDB-3Q29-1 RCSB PDB | xray | resolution: 2.3 Å | in vitro · -173.15 °C · pH 8 · ligands GOL, SO4, branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Cyrstal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) · Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A,C) | unmapped |
| EV-PDB-3Q28-1 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 9 · ligands SO4, branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Cyrstal structure of human alpha-synuclein (58-79) fused to maltose binding protein (MBP) · Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A) | unmapped |
| EV-PDB-3Q27-1 RCSB PDB | xray | resolution: 1.302 Å | in vitro · -173.15 °C · pH 9 · ligands GOL, SO4, branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP) · Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A) | unmapped |
| EV-PDB-3Q25-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 8 · ligands GOL, SO4, branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) · Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A) | unmapped |
| EV-PDB-36QD-1 RCSB PDB | cryoem | resolution: 3.05 Å | in vitro Cryo-EM of rPFFs (recombinant preformed fibrils) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-34AH-1 RCSB PDB | nmr_structure | structure | in vitro · 7.85 °C · pH 7.4 · ligands CU Cu(II) - alpha-synuclein monomer complex - local structure of binding site His50 with Glu46 as ligand · Alpha-synuclein (chains A) | unmapped |
| EV-PDB-34AG-1 RCSB PDB | nmr_structure | structure | in vitro · 7.85 °C · pH 7.4 · ligands CU Cu(II) - alpha-synuclein monomer complex - local structure of binding site His50 with Gly47 as ligand · Alpha-synuclein (chains A) | unmapped |
| EV-PDB-34AF-1 RCSB PDB | nmr_structure | structure | in vitro · 7.85 °C · pH 7.4 · ligands CU Cu(II)-bound alpha-synuclein monomer complex - local structure of N-terminal binding site · Alpha-synuclein (chains A) | unmapped |
| EV-PDB-2X6M-2 RCSB PDB | xray | resolution: 1.62 Å | in vitro · -100.15 °C · pH 7.5 Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein · ALPHA-SYNUCLEIN PEPTIDE (chains B) | unmapped |
| EV-PDB-2N0A-1 RCSB PDB | nmr_structure | structure | in vitro · pH 7 Atomic-resolution structure of alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-2M55-2 RCSB PDB | nmr_structure | structure | in vitro · 36.85 °C · pH 6.36 · ligands CA NMR structure of the complex of an N-terminally acetylated alpha-synuclein peptide with calmodulin · Alpha-synuclein (chains B) | unmapped |
| EV-PDB-2JN5-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6.5 Solution Structure of a Dodecapeptide from Alpha-Synuclein Bound with Synphilin-1 · Alpha-synuclein (chains A) | unmapped |
| EV-PDB-1XQ8-1 RCSB PDB | nmr_structure | structure | in vitro · 25.05 °C · pH 7.4 Human micelle-bound alpha-synuclein · Alpha-synuclein (chains A) | helical, micelle-bound · curator:draft (unreviewed) · medium NMR structure of the micelle-bound helical form; membrane-mimetic conditions, so confidence is medium. |
| EV-PDB-12AT-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Cryo-EM structure of alpha-synuclein filaments (doublet) from M83(+/+) mouse brains with A53T mutation · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-12AR-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Cryo-EM structure of alpha-synuclein filaments (singlet) from M83(+/+) mouse brains with A53T mutation · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-12AQ-1 RCSB PDB | cryoem | resolution: 2.1 Å | in vitro Cryo-EM structure of alpha-synuclein filaments (doublet) from Parkinson's disease with A53T mutation in SNCA · Alpha-synuclein (chains J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-12AP-1 RCSB PDB | cryoem | resolution: 2.1 Å | in vitro Cryo-EM structure of alpha-synuclein filaments (singlet) from Parkinson's disease with A53T mutation in SNCA · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-10XU-1 RCSB PDB | cryoem | resolution: 3.18 Å | in vitro Structure of amplified aSyn filament by using seed amplification assay (SAA) from MSA patient CSF. · Alpha-synuclein (chains A,B,C,D,E,U,W,X,Y,Z) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7C1D-1 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro Cryo-EM structure of the hE46K cross-seeded hWT alpha-synuclein fibril · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7L7H-1 RCSB PDB | cryoem | resolution: 4 Å | in vitro Alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7NCG-1 RCSB PDB | cryoem | resolution: 3.43 Å | in vitro Type 2A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7NCH-1 RCSB PDB | cryoem | resolution: 3.84 Å | in vitro Type 1B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7NCJ-1 RCSB PDB | cryoem | resolution: 4.23 Å | in vitro Type 2AB alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7NCK-1 RCSB PDB | cryoem | resolution: 3.18 Å | in vitro Type 3 alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 5 · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7OZG-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro PMCA-amplified alpha-synuclein fibril polymorph, Parkinson's Disease patient-derived seeds · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7OZH-1 RCSB PDB | cryoem | resolution: 3.02 Å | in vitro PMCA-amplified alpha-synuclein fibril polymorph, Multiple System Atrophy patient-derived seeds · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7UAK-1 RCSB PDB | cryoem | resolution: 3.38 Å | in vitro Structure of recombinantly assembled A53E alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7V49-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient · Alpha-synuclein (chains A,B,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7V4A-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Heparin-induced alpha-synuclein fibrils polymorph 1 · Alpha-synuclein (chains A,B,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7V4B-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Heparin-induced alpha-synuclein fibrils polymorph 3 · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7V4C-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Heparin-induced alpha-synuclein fibrils polymorph 4 · Alpha-synuclein (chains A,B,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7V4D-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro Heparin-remodelled alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7WNZ-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro CryoEM structure of human alpha-synuclein A53T fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7WO0-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions · Alpha-synuclein (chains A,B,C,D,E,F,G,O,P,Q,R,S,T,U) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7XJX-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro The cryo-EM structure of Fe3+ induced alpha-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7XO0-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7XO1-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7XO2-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,I) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7XO3-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YK8-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Cryo-EM structure of dLAG3-alpha-syn fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNF-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro · ligands V79 CCA-bound alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNG-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro CR-bound alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNL-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands IZ8 EB-bound alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNM-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands TFX ThT-bound alpha-synuclein fibrils conformation 1 · Alpha-synuclein (chains A,B,C,D,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNN-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands TFX ThT-bound alpha-synuclein fibrils conformation 2 · Alpha-synuclein (chains A,B,C,D,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNO-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands IZV PiB-bound alpha-synuclein fibrils conformation 1 · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNP-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands IZM BF227-bound alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNR-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro C05-03-bound alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNS-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro SIL5-bound alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNT-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro pFTAA-bound alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8A4L-1 RCSB PDB | cryoem | resolution: 2.68 Å | in vitro Lipidic alpha-synuclein fibril - polymorph L2A · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,O,P) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8A9L-1 RCSB PDB | cryoem | resolution: 2.2 Å | in vitro Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ADS-1 RCSB PDB | cryoem | resolution: 3.05 Å | in vitro Lipidic alpha-synuclein fibril - polymorph L2B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ADU-1 RCSB PDB | cryoem | resolution: 3.24 Å | in vitro Lipidic alpha-synuclein fibril - polymorph L1A · Alpha-synuclein (chains A,B,C,D,E) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ADV-1 RCSB PDB | cryoem | resolution: 2.98 Å | in vitro Lipidic alpha-synuclein fibril - polymorph L1B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8B9V-3 RCSB PDB | xray | resolution: 2.16 Å | in vitro · -173.15 °C · pH 8 · ligands ZN Crystal structure of Lu AF82422 in complex with alpha-synuclein 110-120 · Alpha-synuclein 110-120 (chains A) | unmapped |
| EV-PDB-8AEX-1 RCSB PDB | cryoem | resolution: 2.76 Å | in vitro Lipidic alpha-synuclein fibril - polymorph L3A · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ADW-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro Lipidic alpha-synuclein fibril - polymorph L1C · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YNQ-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands IZV PiB-bound alpha-synuclein fibrils conformation 2 · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7YK2-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Cryo-EM structure of Apo-alpha-syn fibril · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7WMM-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands 1KI alpha-synuclein fibril-F0502B complex · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7V48-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7V47-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7STX-3 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro · ligands COA Cryo-EM structure of human NatB in complex with CoA-Alpha-Synuclein · Alpha-synuclein (chains C) | unmapped |
| EV-PDB-7NCI-1 RCSB PDB | cryoem | resolution: 3.55 Å | in vitro Type 2B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7NCA-1 RCSB PDB | cryoem | resolution: 3.47 Å | in vitro Type 1A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-7LC9-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Cryo-EM structure of the N-terminal alpha-synuclein truncation 41-140 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-7E0F-1 RCSB PDB | cryoem | resolution: 3.02 Å | in vitro CryoEM structure of G51D alpha-synuclein amyloid fibril · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CE7-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein · Alpha-synuclein (chains A,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8Y2P-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro The cryo-EM structure of a-synuclein fibril in Tris buffer. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8XWD-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands KDH Croy-EM structure of alpha synuclein fibril with EGCG · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8X7R-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands Y9W C05-03-bound E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8X7Q-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro · ligands 3LS pFTAA-bound E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8X7P-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro · ligands V79 CCA-bound E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8X7O-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro · ligands IZV PiB-bound E46K mutanted alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8X7M-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands 59P CR-bound E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8X7L-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands IZ8 EB-bound E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8X7B-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands TFX ThT-bound E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8RRR-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Alpha-synuclein amyloid fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8RQM-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Alpha-synuclein amyloid fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8RI9-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Late alpha-Synuclein fibril structure from liquid-liquid phase separations. · Alpha-synuclein (chains A,B,C,D,E) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8QPZ-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro CryoEM structure of recombinant DeltaN7 alpha-synuclein in PBS · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-8PK4-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Cryo EM structure of the type 5A polymorph of alpha-synuclein. · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8PK2-1 RCSB PDB | cryoem | resolution: 3.26 Å | in vitro Cryo EM structure of the type 1m polymorph of alpha-synuclein · Alpha-synuclein (chains A,B,C,D,E) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8PJO-1 RCSB PDB | cryoem | resolution: 2.31 Å | in vitro · ligands CL Cryo EM structure of the type 3D polymorph of alpha-synuclein E46K mutant at low pH. · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8PIX-1 RCSB PDB | cryoem | resolution: 3.41 Å | in vitro Cryo EM structure of the type 3C polymorph of alpha-synuclein at low pH. · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8OQI-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Cryo-EM structure of the wild-type alpha-synuclein fibril. · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8OL8-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6.5 Solution NMR Structure of Lactamised Alpha-Synuclein 2-12 Peptide in 50% TFE. · ACE-ASP-VAL-PHE-MET-LYS-LYS-LEU-SER-LYS-ASP-LYS-NH2 (chains A) | unmapped |
| EV-PDB-8OJR-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6.5 Solution NMR Structure of Alpha-Synuclein 1-25 Peptide in 50% TFE. · Alpha-synuclein (chains A) | unmapped |
| EV-PDB-8OG0-3 RCSB PDB | xray | resolution: 1.712 Å | in vitro · -173.15 °C · pH 5 Crystal structure of MJF14-6-4-2 Fab fragment in complex with epitope peptide · Alpha-synuclein (chains P) | unmapped |
| EV-PDB-8JLY-2 RCSB PDB | xray | resolution: 1.29 Å | in vitro · -173.15 °C · ligands GOL Structure of nanobody in complex with alpha-synuclein peptide · alpha-synuclein peptide (chains B) | unmapped |
| EV-PDB-8JJV-2 RCSB PDB | xray | resolution: 1.23 Å | in vitro · -173.15 °C · ligands GOL Structure of truncated form of nanobody in complex with alpha-synuclein peptide · Alpha-synuclein peptide (chains B) | unmapped |
| EV-PDB-8JEY-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro Cryo-EM structure of alpha-synuclein pS87 fibril · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8JEX-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands NAG Cryo-EM structure of alpha-synuclein gS87 fibril · Alpha-synuclein (chains A,B,G,H,K,P) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8HZS-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Formed alpha-synuclein fibrils after incubation with heparin for 3 days (Hep-remod-3) · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8HZC-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-2) · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8HZB-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1) · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8H05-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient · Alpha-synuclein (chains A,B,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8H04-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8H03-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8GF7-1 RCSB PDB | cryoem | resolution: 4.8 Å | in vitro · ligands NAG Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8G0L-3 RCSB PDB | cryoem | resolution: 3.39 Å | in vitro · ligands CMC Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies · Alpha-synuclein (chains C) | unmapped |
| EV-PDB-8FPT-1 RCSB PDB | nmr_structure | structure | in vitro · -0.15 °C · pH 7.6 STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CZ6-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X · Alpha-synuclein (chains A,B,C,D,E,F,G,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CZ3-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case X · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CZ2-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CZ1-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CZ0-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CYY-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CYX-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III · Alpha-synuclein (chains A,B,C,D,E,I,J,K,L,M) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CYW-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CYV-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CYT-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I · Alpha-synuclein (chains A,B,C,D,E,F,G,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CYS-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I · Alpha-synuclein (chains A,B,C,D,E,F,G,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CYR-1 RCSB PDB | cryoem | resolution: 4.2 Å | in vitro Alpha-synuclein fibril from spontaneous control · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8CEB-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Type2 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein · Alpha-synuclein (chains A,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8BQW-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy · Alpha-synuclein (chains A,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8BQV-1 RCSB PDB | cryoem | resolution: 2 Å | in vitro Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8Y2Q-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro The cryo-EM structure of spermine induced a-synuclein fibril in Tris buffer. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ZLI-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro · ligands A1L13 BTA-2-bound E46K alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ZLO-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands 1KI F0502B-bound E46K alpha-synuclein fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,O,T) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ZLP-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro apo WT polymorph 5a alpha-synuclein fibril · Alpha-synuclein (chains A,B,C,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ZVY-2 RCSB PDB | xray | resolution: 1.72 Å | in vitro · -173.15 °C · pH 8 · ligands CL Alpha-Synuclein with H2a-H2b dimer complex structure. · Isoform 1 of Alpha-synuclein (chains C,D) | unmapped |
| EV-PDB-8ZWH-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro Heparin bound E46K alpha-synuclein fibril · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9A1A-1 RCSB PDB | integrative | structure | in vitro The ensemble structure of alpha-synuclein monomer · alpha-synuclein (chains A) | disordered monomer · rule:as-integrative-monomer · medium Integrative ensemble of the monomer. |
| EV-PDB-9C5R-1 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro Structure of recombinantly assembled alpha-synuclein variant fibrils · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9CD9-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Structure of type II-2 alpha-synuclein filament from multiple system atrophy · Alpha-synuclein (chains E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9CDA-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Structure of type I-2 alpha-synuclein filament from multiple system atrophy · Alpha-synuclein (chains K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,a,b) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9CK3-1 RCSB PDB | cryoem | resolution: 2.04 Å | in vitro Cryo-EM structure of in-vitro alpha-synuclein fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9CX6-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Cryo-EM filament structure in FTLD-synuclein · Alpha-synuclein (chains G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9D5C-1 RCSB PDB | cryoem | resolution: 4.8 Å | in vitro · ligands NAG Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9E8U-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro (Apo)Alpha-synuclein fibril structures from MSA patient brain · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9E8W-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands A1BGB Complex fibril structure of MSA alpha-synuclein with CNS-11g at 6 hours · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9E9X-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Cryo-EM structure of alpha-synuclein filaments derived from the temporal cortex of the case of atypical multiple system atrophy · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9EUU-1 RCSB PDB | cryoem | resolution: 1.93 Å | in vitro Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HC8-1 RCSB PDB | cryoem | resolution: 2.82 Å | in vitro The L2C alpha-synuclein fibril in the presence of MODAG-005 (short incubation) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HCA-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro The L2A-II alpha-synuclein fibril in the presence of MODAG-005 (long incubation) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HCB-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro The L2C alpha-synuclein fibril in the presence of MODAG-005 (long incubation) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HGR-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro In vitro grown WT Alpha-Synuclein Fibrils · Alpha-synuclein (chains A,B) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HGS-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro In vitro grown G14R Alpha-Synuclein Fibrils · Alpha-synuclein (chains C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HXA-1 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro In vitro grown K58N Alpha-Synuclein Fibrils · Alpha-synuclein (chains A,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9IJP-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands 7TT Polyphosphate bound alpha-synuclein fibril · Alpha-synuclein (chains B,C,E,G,I,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JC3-1 RCSB PDB | cryoem | resolution: 2.39 Å | in vitro The cryo-EM structure of Ac-G51DA53T P1 a-syn fibril. · Alpha-synuclein (chains D,E,F,G,H,I) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JC5-1 RCSB PDB | cryoem | resolution: 3.23 Å | in vitro The cryo-EM structure of Ac-G51DA53T P3 a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JD7-1 RCSB PDB | cryoem | resolution: 3.57 Å | in vitro The cryo-EM structure of Ac-G51DA53T a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JDK-1 RCSB PDB | cryoem | resolution: 3.32 Å | in vitro The cryo-EM structure of Ac-G51DA53T P6 a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JE2-1 RCSB PDB | cryoem | resolution: 3.06 Å | in vitro The cryo-EM structure of Ac-K58N_G51DA53T a-syn fibril. · Alpha-synuclein (chains C,D,E,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JE4-1 RCSB PDB | cryoem | resolution: 3.37 Å | in vitro The cryo-EM structure of Ac-E57A_G51DA53T a-syn fibril. · Alpha-synuclein (chains A,B,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JE6-1 RCSB PDB | cryoem | resolution: 3.43 Å | in vitro The cryo-EM structure of Ac-G51DA53T low salt a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JD8-1 RCSB PDB | cryoem | resolution: 3.86 Å | in vitro The cryo-EM structure of Ac-G51DA53T P5 a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JC4-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro The cryo-EM structure of Ac-G51DA53T P2 a-syn fibril. · Alpha-synuclein (chains B,C,D,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JBY-1 RCSB PDB | cryoem | resolution: 3.49 Å | in vitro The cryo-EM structure of Ac-K58W_G51DA53T a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9IC7-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Cryo-EM structure of alpha-synuclein fibrils formed in artificial cerebrospinal fluid (aCSF) · Alpha-synuclein (chains a,b,c,d,e,f,g,h,i,j,k,l,m,n) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HC9-1 RCSB PDB | cryoem | resolution: 2.76 Å | in vitro The L2A-I alpha-synuclein fibril in the presence of MODAG-005 (long incubation) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HC7-1 RCSB PDB | cryoem | resolution: 2.85 Å | in vitro The L2A-II alpha-synuclein fibril in the presence of MODAG-005 (short incubation) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9HC6-1 RCSB PDB | cryoem | resolution: 2.79 Å | in vitro The L2A-I alpha-synuclein fibril in the presence of MODAG-005 (short incubation) · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9FYP-1 RCSB PDB | cryoem | resolution: 2.23 Å | in vitro · ligands CL Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH. · Alpha-synuclein (chains I,J,K,L,M,N,O,P,Q,R) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9E8Y-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands A1BGB Complex fibril structure of MSA alpha-synuclein with CNS-11g at 15 hours · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9E8X-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands A1BGB Complex fibril structure of MSA alpha-synuclein with CNS-11g at 10 hours · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9E8V-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro · ligands A1BGB Complex fibril structure of MSA alpha-synuclein with CNS-11g at 4 hours · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9CKL-1 RCSB PDB | cryoem | resolution: 2.68 Å | in vitro Cryo-EM structure of acetylated alpha-synuclein A53T fibril - polymorph B · Alpha-synuclein (chains A,B,C,D,E,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9CKK-1 RCSB PDB | cryoem | resolution: 2.21 Å | in vitro Cryo-EM structure of acetylated alpha-synuclein A53T fibril - polymorph A · Alpha-synuclein (chains A,B,C,D,E,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9A1Q-1 RCSB PDB | integrative | structure | in vitro The structural models of alpha-synuclein dimer · alpha-synuclein (chains A,B) | unmapped |
| EV-PDB-9A1H-1 RCSB PDB | integrative | structure | in vitro Integrative structural model of alpha-synuclein compact states bound to membrane mimics · alpha-synuclein (chains A,B) | unmapped |
| EV-PDB-8ZWK-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Polyadenylic acid bound alpha-synuclein fibril Polymorph 2 · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ZWJ-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Polyadenylic acid bound alpha-synuclein fibril Polymorph 1 · Alpha-synuclein (chains A,B,C,D,E,G) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ZWI-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Chondroitin sulfate bound alpha-synuclein fibril · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-8ZMY-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands 1KI F0502B-bound WT polymorph 5a alpha-synuclein fibril · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JI8-2 RCSB PDB | cryoem | resolution: 2.85 Å | in vitro Cryo-EM structure of alpha-synuclein-H21 fibril · Alpha-synuclein (chains F,G,K,L,M,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9K7Q-2 RCSB PDB | xray | resolution: 4.58 Å | in vitro · -173.15 °C Parkinson disease protein 7 (DJ-1) and Alpha-synuclein (Alpha-syn) complex · Alpha-synuclein (chains M) | unmapped |
| EV-PDB-9KA4-1 RCSB PDB | cryoem | resolution: 3.42 Å | in vitro The cryo-EM structure of MSA-like fold (P1) formed under the palette stratagy. · Alpha-synuclein (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-9KCN-2 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands A1EFL Cryo-EM structure of FD4-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains L,M,N,P,Q,R,d,e,f,h,i,j) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9O4B-1 RCSB PDB | cryoem | resolution: 2.59 Å | in vitro · ligands A1B9H Cryo-EM structure of in-vitro alpha-synuclein fibril bound with Exemplar-6 PET-radioligand · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9OBP-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro Cryo-EM structure of alpha-synuclein filaments derived from the frontal cortex of the case of atypical multiple system atrophy · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9QYN-1 RCSB PDB | cryoem | resolution: 3.13 Å | in vitro Alpha-synuclein K21A fibril type 1A polymorph in the presence of ATP · Alpha-synuclein (chains G,H,I,J,K,L,M,N,O,P) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9RBB-1 RCSB PDB | cryoem | resolution: 3.15 Å | in vitro Wild-type alpha-synuclein fibril - Type 5 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9TPT-1 RCSB PDB | cryoem | resolution: 3.43 Å | in vitro Structure of recombinantly assembled E83Q alpha-synuclein fibrils · Alpha-synuclein (chains A,B,C,D,E,F,H,I,J,L,M,N) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UFF-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands A1EO6 Cryo-EM structure of BA21-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9W09-2 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro The cryo-EM structure of 30-140 P2 a-syn fibril. · Alpha-synuclein (chains O,P,Q,U,V,W) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9W08-1 RCSB PDB | cryoem | resolution: 2.87 Å | in vitro The cryo-EM structure of 30-140 P1 a-syn fibril. · Alpha-synuclein (chains D,E,F,G,H,I) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9W07-1 RCSB PDB | cryoem | resolution: 3.03 Å | in vitro The cryo-EM structure of Ac-Y39EK45GK58G 30-140 a-syn fibril. · Alpha-synuclein (chains C,D,E,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9W06-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro The cryo-EM structure of Y39EE83G a-syn fibril. · Alpha-synuclein (chains B,C,D) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9V7C-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands A1EFL The cryo-EM structure of FD4_orientation2 bound Lewy fold fibril. · Alpha-synuclein (chains c,d,e,f,g,h,i,j,k,o,p,q,r,s,t) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9V6U-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands A1EFL The cryo-EM structure of FD4 bound Lewy fold fibril. · Alpha-synuclein (chains c,d,e,f,g,h,i,j,k,o,p,q,r,s,t) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UJQ-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Cryo-EM structure of HQY1027-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UG1-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands A1EPB Cryo-EM structure of HA32-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UG0-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands A1EPK Cryo-EM structure of HA31-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UFY-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands GO3 Cryo-EM structure of HA21-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UFX-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands A1EPA Cryo-EM structure of HA11-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UFS-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Cryo-EM structure of BA23-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UFL-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro Cryo-EM structure of BA22-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UFD-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro · ligands A1EO8 Cryo-EM structure of BA12-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains E,F,G,H,I,J,K,L,M,N,O,P) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9UF6-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands A1EO7 Cryo-EM structure of BA1-1-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains E,F,G,H,I,J,K,L,M,N,O,P) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9RBA-1 RCSB PDB | cryoem | resolution: 3.54 Å | in vitro Wild-type alpha-synuclein fibril - Type 4 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9RB9-1 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro Wild-type alpha-synuclein fibril - Type 3-2 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9RB8-1 RCSB PDB | cryoem | resolution: 3.64 Å | in vitro Wild-type alpha-synuclein fibril - Type 3-1 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9RB7-1 RCSB PDB | cryoem | resolution: 3.45 Å | in vitro Wild-type alpha-synuclein fibril - Type 1 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9RB6-1 RCSB PDB | cryoem | resolution: 3.02 Å | in vitro A53T alpha-synuclein fibril - Type 2 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9RB3-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro A53T alpha-synuclein fibril - Type 1 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9QYL-1 RCSB PDB | cryoem | resolution: 3.08 Å | in vitro Alpha-synuclein fibril type 1A polymorph in the presence of ATP · Alpha-synuclein (chains E,F,G,H,J,K,L,M,N,O,P,Q,e,f,g,h,j,k,l,m,n,o,p,q) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9PTC-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Alpha-synuclein acetylated lysine 80 A · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-9PTB-1 RCSB PDB | cryoem | resolution: 2.94 Å | in vitro Alpha-synuclein acetylated lysine 80 B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-9PTA-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Alpha-synuclein A · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-9PT9-1 RCSB PDB | cryoem | resolution: 3.06 Å | in vitro Alpha-synuclein B · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-9PT8-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Alpha-synuclein acetylated lysine 80 · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-9O9K-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with H50Q variant in SNCA · Alpha-synuclein (chains A) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9O9J-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with G51D mutaion in SNCA · Alpha-synuclein (chains A,D) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9M5L-1 RCSB PDB | cryoem | resolution: 3.27 Å | in vitro The cryo-EM structure of in situ amplified (ISA) alpha-synuclein fibrils from DLB homogenate · Alpha-synuclein (chains A,B,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9M5K-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro The cryo-EM structure of in situ amplified (ISA) alpha-synuclein fibrils from PD homogenate · Alpha-synuclein (chains A,B,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9KCP-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Cryo-EM structure of ACI-12589-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains D,E,F,G,H,I) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9KCO-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands A1EFL Cryo-EM structure of FD4-bound alpha-synuclein MSA-like fibril · Alpha-synuclein (chains F,G,H,I,J,K,L,M,N,O,P,Q) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9KC2-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro · ligands A1EFK Cryo-EM structure of ZSQ07-bound alpha-synuclein fibril polymorph 6A6B · Alpha-synuclein (chains C,D,E,F,G,H) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9KAL-1 RCSB PDB | cryoem | resolution: 3.36 Å | in vitro The cryo-EM structure of Ac-E57A_G51DA53T a-syn fibril. · Alpha-synuclein (chains A,B,C) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9KA3-1 RCSB PDB | cryoem | resolution: 2.72 Å | in vitro The cryo-EM structure of Ac-K58D_G51DA53T a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JO6-1 RCSB PDB | nmr_structure | structure | in vitro · 10 °C · pH 7.5 The complex of alpha-synuclein in the presence of PD6 · Alpha-synuclein (chains A) | unmapped |
| EV-PDB-9JKE-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro The cryo-EM structure of Ac-K58W_G51DA53T P2 a-syn fibril. · Alpha-synuclein (chains A,B,C,D,E,F) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JE8-1 RCSB PDB | cryoem | resolution: 3.6 Å | in vitro The cryo-EM structure of Ac-G51DA53T 30days a-syn fibril. · Alpha-synuclein (chains B,C,D,E,F,G) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9JE7-1 RCSB PDB | cryoem | resolution: 3.36 Å | in vitro The cryo-EM structure of Ac-E57Q_G51DA53T a-syn fibril. · Alpha-synuclein (chains A,C,E) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9W1T-2 RCSB PDB | cryoem | resolution: 3 Å | in vitro The cryo-EM structure of 30-140 P3 a-syn fibril. · Alpha-synuclein (chains M,N,O) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9YFC-1 RCSB PDB | nmr_structure | structure | in vitro · -0.15 °C · pH 7.5 Structure of A30P Alpha-synuclein Fibrils · Alpha-synuclein (chains A,B,C,D,E) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-PDB-9Y0S-1 RCSB PDB | cryoem | resolution: 2.72 Å | in vitro CryoEM structure of alpha-synuclein fibril induced by psychosine · Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J) | fibril · rule:as-fibril-title · high Structure titled as a fibril, filament or amyloid polymorph. |
| EV-BMRB-15095 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.5 Solution Structure of a Dodecapeptide from Alpha-Synuclein Bound with Synphilin-1 · BMRB data: 1H chemical shifts | unmapped |
| EV-BMRB-16300 BMRB | nmr_shifts | chemical_shift | in vitro · 15.05 °C · pH 7.4 intrinsically unfolded alpha-synuclein · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-16302 BMRB | nmr_shifts | chemical_shift | in vitro · 25.05 °C · pH 7.4 SLAS-bound alpha-synuclein · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-16342 BMRB | nmr_dynamics | relaxation_rate | in vitro · 14.85 °C · pH 3 Backbone 1H, 13C, 15N and 13C-beta Chemical Shift Assignments for alpha-synuclein at pH 3 · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts, heteronuclear NOE values, residual dipolar couplings | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-16543 BMRB | nmr_shifts | chemical_shift | in vitro · 19.85 °C · pH 6 Backbone 1H and 15N Chemical Shifts for Disordered alpha-Synuclein · BMRB data: 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-16546 BMRB | nmr_shifts | chemical_shift | in vitro · 19.85 °C · pH 6 Backbone 1H and 15N Chemical Shifts for Disordered A30P alpha-Synuclein · BMRB data: 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-16547 BMRB | nmr_shifts | chemical_shift | in vitro · 19.85 °C · pH 6 Backbone 1H and 15N Chemical Shifts for Disordered E46K alpha-Synuclein · BMRB data: 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-16548 BMRB | nmr_shifts | chemical_shift | in vitro · 19.85 °C · pH 6 Backbone 1H and 15N Chemical Shifts for Disordered A53T alpha-Synuclein · BMRB data: 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-16904 BMRB | nmr_dynamics | relaxation_rate | in vitro · 14.85 °C · pH 7.4 Backbone assignment of human alpha-synuclein in viscous 2 M glucose solution · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts, T2 relaxation values | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-16939 BMRB | nmr_shifts | chemical_shift | in vitro · 9.85 °C · pH 7.5 WT alpha-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-17214 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.5 A30P alpha-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-17498 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.5 Solid-state NMR assignment of alpha-synuclein amyloid fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-17648 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.5 Partial 13C,15N chemical shift assignments of A30P alpha-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-17654 BMRB | nmr_shifts | chemical_shift | in vitro · 9.85 °C · pH 7.5 Partial 13C, 15N chemical shift assignments of E46K alpha-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-17910 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 WT alpha-synuclein fibrils in the presence of phospholipid vesicles · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-18207 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 A53T alpha-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-18208 BMRB | nmr_shifts | chemical_shift | in vitro · 9.85 °C · pH 7.4 Chemical shift assignments of the E46K alpha-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-18243 BMRB | nmr_shifts | chemical_shift | in vitro · pH 7.4 WT AS fibrils (1H detection experiments) · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-18857 BMRB | nmr_shifts | chemical_shift | in vitro · 9.85 °C · pH 2.16 Backbone 1H, 13C,and 15N chemical shift assignments for alpha-synuclein at different pH and temperature · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-18860 BMRB | nmr_shifts | chemical_shift | in vitro · 4.85 °C · pH 7.5 solid-state NMR assignment of a-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-19036 BMRB | nmr_shifts | chemical_shift | in vitro · 36.85 °C · pH 6.36 NMR structure of the complex of an N-terminally acetylated alpha-synuclein peptide with calmodulin · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-19257 BMRB | nmr_shifts | chemical_shift | in vitro · 3.85 °C · pH 6.2 1H, 13C, and 15N chemical shift assignments for alpha-synuclein in living E. coli cells · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-19337 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 alpha synuclein in PBS · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-19338 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 alpha synuclein mutant A53T in PBS · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-19344 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 alpha synuclein mutant S87N in PBS - human/mouse chimera · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-19345 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 alpha synuclein mutant A53T & S87N in PBS - human/mouse chimera · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-19350 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 Acetylated alpha synuclein in PBS · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-19351 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 Acetylated alpha synuclein A53T familiar mutant in PBS · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-19353 BMRB | nmr_shifts | chemical_shift | in vitro · 29.85 °C · pH 7.4 Structure of alpha-synuclein in complex with an engineered binding protein · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-25227 BMRB | nmr_shifts | chemical_shift | in vitro · 9.85 °C · pH 7.5 1H, 13C, and 15N chemical shift assignments for alpha-synuclein monomer (WT) · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-25228 BMRB | nmr_shifts | chemical_shift | in vitro · 9.85 °C · pH 7.5 1H, 13C, and 15N chemical shift assignments for alpha-synuclein (H50Q) · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-25518 BMRB | nmr_shifts | chemical_shift | in vitro · pH 7 Atomic-resolution structure of alpha-synuclein fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-31068 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.6 STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-31269 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.5 Structure of A30P Alpha-synuclein Fibrils · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-34800 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.5 Solution NMR Structure of Alpha-Synuclein 1-25 Peptide in 50% TFE. · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-34801 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.5 Solution NMR Structure of Lactamised Alpha-Synuclein 2-12 Peptide in 50% TFE. · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-35086 BMRB | nmr_shifts | chemical_shift | in vitro · 7.85 °C · pH 7.4 Cu(II)-bound alpha-synuclein monomer complex - local structure of N-terminal binding site · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-35087 BMRB | nmr_shifts | chemical_shift | in vitro · 7.85 °C · pH 7.4 Cu(II) - alpha-synuclein monomer complex - local structure of binding site His50 with Gly47 as ligand · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-35088 BMRB | nmr_shifts | chemical_shift | in vitro · 7.85 °C · pH 7.4 Cu(II) - alpha-synuclein monomer complex - local structure of binding site His50 with Glu46 as ligand · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-36696 BMRB | nmr_shifts | chemical_shift | in vitro · 10 °C · pH 7.5 The complex of alpha-synuclein in the presence of PD6 · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-50996 BMRB | nmr_shifts | chemical_shift | in vitro · 49.85 °C · pH 5.5 SDS-Micelle bound alpha-Synuclein · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | helical, micelle-bound · rule:as-micelle-title · medium Structure titled as micelle-bound. |
| EV-BMRB-51120 BMRB | nmr_shifts | chemical_shift | in vitro · 15 °C · pH 7.5 Single residue switches of aggregation in the N-terminal 'master controller' region of alpha-synuclein · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-51121 BMRB | nmr_shifts | chemical_shift | in vitro · 15 °C · pH 7.5 Single residue switches of aggregation in the N-terminal 'master controller' region of alpha-synuclein · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-51148 BMRB | nmr_shifts | chemical_shift | in vitro · 49.85 °C · pH 5.5 Bicelle-bound alpha-Synuclein · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-51152 BMRB | nmr_shifts | chemical_shift | in vitro · 49.85 °C · pH 5.5 alpha-Synuclein at low pH and high Temperature · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-5744 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 7.4 Backbone Assignments of folded alpha-synuclein · BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-BMRB-6968 BMRB | nmr_shifts | chemical_shift | in vitro · 12.35 °C · pH 6.5 1H, 13C and 15N assignment of C', CA, CB, N, HN, HA and HB of intrinsically disordered alpha-synuclein · BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-SASBDB-SASD2J3 SASBDB | saxs_sans | radius_of_gyration: 2.912 nm ± 0.028 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2K3 SASBDB | saxs_sans | radius_of_gyration: 2.938 nm ± 0.02 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2L3 SASBDB | saxs_sans | radius_of_gyration: 2.926 nm ± 0.016 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2M3 SASBDB | saxs_sans | radius_of_gyration: 3.416 nm ± 0.026 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2N3 SASBDB | saxs_sans | radius_of_gyration: 3.37 nm ± 0.018 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2P3 SASBDB | saxs_sans | radius_of_gyration: 3.423 nm ± 0.026 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2Q3 SASBDB | saxs_sans | radius_of_gyration: 3.421 nm ± 0.017 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2R3 SASBDB | saxs_sans | radius_of_gyration: 3.418 nm ± 0.014 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2S3 SASBDB | saxs_sans | radius_of_gyration: 3.438 nm ± 0.025 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2T3 SASBDB | saxs_sans | radius_of_gyration: 3.407 nm ± 0.017 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-SASBDB-SASD2U3 SASBDB | saxs_sans | radius_of_gyration: 3.434 nm ± 0.013 | in vitro · 20 °C · pH 7.2 α-Synuclein with K to R mutations and different NaCl concentration · Alpha-synuclein | disordered monomer · rule:as-saxs-monomer · low SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex. |
| EV-DISPROT-DP00070r001 DisProt | gel_electrophoresis | disorder_region: 140 residues | in vitro DisProt DP00070: disorder, residues 1-140 · residues 1-140; evidence: sodium dodecyl sulfate polyacrylamide gel electrophoresis evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r007 DisProt | nmr_shifts | disorder_region: 41 residues | in vitro DisProt DP00070: disorder, residues 100-140 · residues 100-140; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r011 DisProt | cd | disorder_region: 140 residues | in vitro DisProt DP00070: disorder, residues 1-140 · residues 1-140; evidence: far-UV circular dichroism evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r013 DisProt | epr_deer | disorder_region: 51 residues | in vitro DisProt DP00070: disorder, residues 42-92 · residues 42-92; evidence: site-directed spin-labelling electron paramagnetic resonance evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r014 DisProt | epr_deer | disorder_region: 51 residues | in vitro DisProt DP00070: disorder to order, residues 42-92 · residues 42-92; evidence: site-directed spin-labelling electron paramagnetic resonance evidence used in manual assertion | unmapped |
| EV-DISPROT-DP00070r016 DisProt | cd | disorder_region: 140 residues | in vitro DisProt DP00070: disorder, residues 1-140 · residues 1-140; evidence: far-UV circular dichroism evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r018 DisProt | cd | disorder_region: 140 residues | in vitro DisProt DP00070: disorder to order, residues 1-140 · residues 1-140; evidence: far-UV circular dichroism evidence used in manual assertion | unmapped |
| EV-DISPROT-DP00070r020 DisProt | cd | disorder_region: 140 residues | in vitro DisProt DP00070: disorder, residues 1-140 · residues 1-140; evidence: far-UV circular dichroism evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r026 DisProt | nmr_shifts | disorder_region: 102 residues | in vitro DisProt DP00070: disorder to order, residues 1-102 · residues 1-102; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion | disordered monomer · rule:as-nmr-monomer · low NMR entry not titled as fibril, micelle, membrane or complex: most describe the free monomer. |
| EV-DISPROT-DP00070r028 DisProt | nmr_shifts | disorder_region: 140 residues | in vitro DisProt DP00070: disorder, residues 1-140 · residues 1-140; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r030 DisProt | cd | disorder_region: 140 residues | in vitro DisProt DP00070: disorder, residues 1-140 · residues 1-140; evidence: circular dichroism evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r032 DisProt | ftir_raman | disorder_region: 140 residues | in vitro DisProt DP00070: disorder, residues 1-140 · residues 1-140; evidence: Fourier-transform infrared spectroscopy evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r035 DisProt | cd | disorder_region: 102 residues | in vitro DisProt DP00070: disorder to order, residues 1-102 · residues 1-102; evidence: far-UV circular dichroism evidence used in manual assertion | unmapped |
| EV-DISPROT-DP00070r037 DisProt | nmr_shifts | disorder_region: 103 residues | in vitro DisProt DP00070: disorder, residues 1-103 · residues 1-103; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP00070r039 DisProt | nmr_shifts | disorder_region: 40 residues | in vitro DisProt DP00070: disorder, residues 101-140 · residues 101-140; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion | disordered monomer · rule:as-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-AFDB-AF-P37840-F1 AlphaFold DB | af_prediction | plddt: 75.19 pLDDT | in silico AlphaFold DB prediction AF-P37840-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-140 | unmapped |
| EV-SMASH-SMFS-000607 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Single-Molecule Insight Into α-Synuclein Fibril Structure and Mechanics Modulated by Chemical Compounds. · α-Synuclein; optical tweezers; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001791 SMASH-BIO | force_spectroscopy | study_record | in vitro Wild-Type α-Synuclein and Variants Occur in Different Disordered Dimers and Pre-Fibrillar Conformations in Early Stage of Aggregation. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-002539 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule studies of amyloid proteins: from biophysical properties to diagnostic perspectives. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-002679 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Depicting Conformational Ensembles of α-Synuclein by Single Molecule Force Spectroscopy and Native Mass Spectroscopy. · α-Synuclein; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002852 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing the Basis of α-Synuclein Aggregation by Comparing Simulations to Single-Molecule Experiments. · α-Synuclein; optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-002985 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 A peptide-display protein scaffold to facilitate single molecule force studies of aggregation-prone peptides. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-003130 SMASH-BIO | force_spectroscopy | study_record | in vitro Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-004529 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Diverse metastable structures formed by small oligomers of α-synuclein probed by force spectroscopy. · α-Synuclein; optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-004706 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule force spectroscopy of rapidly fluctuating, marginally stable structures in the intrinsically disordered protein α-synuclein. · α-Synuclein; optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-005089 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 3.7 α-Synuclein misfolding assessed with single molecule AFM force spectroscopy: effect of pathogenic mutations. · α-Synuclein; afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005172 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Effect of spermidine on misfolding and interactions of alpha-synuclein. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-005582 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Nanomechanical properties of α-synuclein amyloid fibrils: a comparative study by nanoindentation, harmonic force microscopy, and Peakforce QNM. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-005647 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Single-molecule atomic force microscopy force spectroscopy study of Aβ-40 interactions. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006039 SMASH-BIO | force_spectroscopy | study_record | in vitro Early stages for Parkinson's development: alpha-synuclein misfolding and aggregation. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006142 SMASH-BIO | force_spectroscopy | study_record | in vitro Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006287 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Conformational equilibria in monomeric alpha-synuclein at the single-molecule level. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006507 SMASH-BIO | force_spectroscopy | study_record | in vitro alpha-Synuclein misfolding: single molecule AFM force spectroscopy study. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007047 SMASH-BIO | force_spectroscopy | study_record | in vitro Protein interactions and misfolding analyzed by AFM force spectroscopy. · α-Synuclein; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007104 SMASH-BIO | force_spectroscopy | study_record | in vitro ABri peptide associated with familial British dementia forms annular and ring-like protofibrillar structures. · α-Synuclein; force spectroscopy unspecified; experiment class: membrane_mechanics | unmapped |
Conflicts
- aS-disordered · radius_of_gyration: 2.912, 3.416 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2M3
differ by 0.504 nm, beyond combined uncertainty 0.0382 - aS-disordered · radius_of_gyration: 2.912, 3.37 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2N3
differ by 0.458 nm, beyond combined uncertainty 0.0333 - aS-disordered · radius_of_gyration: 2.912, 3.423 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2P3
differ by 0.511 nm, beyond combined uncertainty 0.0382 - aS-disordered · radius_of_gyration: 2.912, 3.421 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2Q3
differ by 0.509 nm, beyond combined uncertainty 0.0328 - aS-disordered · radius_of_gyration: 2.912, 3.418 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2R3
differ by 0.506 nm, beyond combined uncertainty 0.0313 - aS-disordered · radius_of_gyration: 2.912, 3.438 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2S3
differ by 0.526 nm, beyond combined uncertainty 0.0375 - aS-disordered · radius_of_gyration: 2.912, 3.407 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2T3
differ by 0.495 nm, beyond combined uncertainty 0.0328 - aS-disordered · radius_of_gyration: 2.912, 3.434 nm · EV-SASBDB-SASD2J3, EV-SASBDB-SASD2U3
differ by 0.522 nm, beyond combined uncertainty 0.0309 - aS-disordered · radius_of_gyration: 2.938, 3.416 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2M3
differ by 0.478 nm, beyond combined uncertainty 0.0328 - aS-disordered · radius_of_gyration: 2.938, 3.37 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2N3
differ by 0.432 nm, beyond combined uncertainty 0.0269 - aS-disordered · radius_of_gyration: 2.938, 3.423 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2P3
differ by 0.485 nm, beyond combined uncertainty 0.0328 - aS-disordered · radius_of_gyration: 2.938, 3.421 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2Q3
differ by 0.483 nm, beyond combined uncertainty 0.0262 - aS-disordered · radius_of_gyration: 2.938, 3.418 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2R3
differ by 0.48 nm, beyond combined uncertainty 0.0244 - aS-disordered · radius_of_gyration: 2.938, 3.438 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2S3
differ by 0.5 nm, beyond combined uncertainty 0.032 - aS-disordered · radius_of_gyration: 2.938, 3.407 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2T3
differ by 0.469 nm, beyond combined uncertainty 0.0262 - aS-disordered · radius_of_gyration: 2.938, 3.434 nm · EV-SASBDB-SASD2K3, EV-SASBDB-SASD2U3
differ by 0.496 nm, beyond combined uncertainty 0.0239 - aS-disordered · radius_of_gyration: 2.926, 3.416 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2M3
differ by 0.49 nm, beyond combined uncertainty 0.0305 - aS-disordered · radius_of_gyration: 2.926, 3.37 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2N3
differ by 0.444 nm, beyond combined uncertainty 0.0241 - aS-disordered · radius_of_gyration: 2.926, 3.423 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2P3
differ by 0.497 nm, beyond combined uncertainty 0.0305 - aS-disordered · radius_of_gyration: 2.926, 3.421 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2Q3
differ by 0.495 nm, beyond combined uncertainty 0.0233 - aS-disordered · radius_of_gyration: 2.926, 3.418 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2R3
differ by 0.492 nm, beyond combined uncertainty 0.0213 - aS-disordered · radius_of_gyration: 2.926, 3.438 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2S3
differ by 0.512 nm, beyond combined uncertainty 0.0297 - aS-disordered · radius_of_gyration: 2.926, 3.407 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2T3
differ by 0.481 nm, beyond combined uncertainty 0.0233 - aS-disordered · radius_of_gyration: 2.926, 3.434 nm · EV-SASBDB-SASD2L3, EV-SASBDB-SASD2U3
differ by 0.508 nm, beyond combined uncertainty 0.0206 - aS-disordered · radius_of_gyration: 3.416, 3.37 nm · EV-SASBDB-SASD2M3, EV-SASBDB-SASD2N3
differ by 0.046 nm, beyond combined uncertainty 0.0316 - aS-disordered · radius_of_gyration: 3.37, 3.423 nm · EV-SASBDB-SASD2N3, EV-SASBDB-SASD2P3
differ by 0.053 nm, beyond combined uncertainty 0.0316 - aS-disordered · radius_of_gyration: 3.37, 3.421 nm · EV-SASBDB-SASD2N3, EV-SASBDB-SASD2Q3
differ by 0.051 nm, beyond combined uncertainty 0.0248 - aS-disordered · radius_of_gyration: 3.37, 3.418 nm · EV-SASBDB-SASD2N3, EV-SASBDB-SASD2R3
differ by 0.048 nm, beyond combined uncertainty 0.0228 - aS-disordered · radius_of_gyration: 3.37, 3.438 nm · EV-SASBDB-SASD2N3, EV-SASBDB-SASD2S3
differ by 0.068 nm, beyond combined uncertainty 0.0308 - aS-disordered · radius_of_gyration: 3.37, 3.407 nm · EV-SASBDB-SASD2N3, EV-SASBDB-SASD2T3
differ by 0.037 nm, beyond combined uncertainty 0.0248 - aS-disordered · radius_of_gyration: 3.37, 3.434 nm · EV-SASBDB-SASD2N3, EV-SASBDB-SASD2U3
differ by 0.064 nm, beyond combined uncertainty 0.0222 - aS-disordered · radius_of_gyration: 3.438, 3.407 nm · EV-SASBDB-SASD2S3, EV-SASBDB-SASD2T3
differ by 0.031 nm, beyond combined uncertainty 0.0302 - aS-disordered · radius_of_gyration: 3.407, 3.434 nm · EV-SASBDB-SASD2T3, EV-SASBDB-SASD2U3
differ by 0.027 nm, beyond combined uncertainty 0.0214
Downloads
- Protein bundle (JSON)
- aS-micelle-helix-cif (mmCIF, observed)
- aS-micelle-helix-pdb (PDB, observed)
- aS-fibril-cif (mmCIF, observed)
- aS-fibril-pdb (PDB, observed)
- Curation file (YAML)