Myosin-9
UniProt P35579 · gene MYH9 · Homo sapiens · 1960 residues
365evidence items
0mapped to a state
0states
6techniques
4sources
0conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | nmr_structure | nmr_shifts | force_spectroscopy | af_prediction | Total |
|---|---|---|---|---|---|---|---|---|
| No states defined yet. | ||||||||
Unmapped evidence: 365 of 365 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 3 | 0 |
| RCSB PDB | 8 | 0 |
| SMASH-BIO | 353 | 0 |
Structure
No state models are exported for this protein yet. Observed states export the representative PDB entry; inferred states need fitted models, not yet built.
States and transitions
No states defined.
| State | Basis | Parent | Description |
|---|
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-9SZR-1 RCSB PDB | cryoem | resolution: 6.3 Å | in vitro · ligands ADP, MG, PO4 shutdown state non-muscle myosin 2A heads region · Isoform 1 of Myosin-9 (chains A,B) | unmapped |
| EV-PDB-9SYU-1 RCSB PDB | cryoem | resolution: 2.98 Å | in vitro · ligands ADP, MG, PO4 shutdown state non-muscle myosin 2A heads region · Isoform 1 of Myosin-9 (chains A,B,G,H) | unmapped |
| EV-PDB-9IHL-1 RCSB PDB | xray | resolution: 2.02 Å | in vitro · -173.15 °C Crystal Structure of the Human Nonmuscle Myosin 2A Motor Domain · Myosin-9,Alpha-actinin A (chains A) | unmapped |
| EV-PDB-4ETO-2 RCSB PDB | xray | resolution: 1.54 Å | in vitro · -173.15 °C · pH 7.5 · ligands CA Structure of S100A4 in complex with non-muscle myosin-IIA peptide · Myosin-9 (chains P) | unmapped |
| EV-PDB-4CFR-2 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 4.6 · ligands CA Ca-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with non- muscle myosin IIA · MYOSIN-9 (chains Q) | unmapped |
| EV-PDB-4CFQ-2 RCSB PDB | xray | resolution: 1.37 Å | in vitro · -173.15 °C · pH 4.6 · ligands CA Ca-bound truncated (delta13C) and C3S, C81S and C86S mutated S100A4 complexed with non-muscle myosin IIA · MYOSIN-9 (chains Q,R) | unmapped |
| EV-PDB-3ZWH-2 RCSB PDB | xray | resolution: 1.94 Å | in vitro · -173.15 °C · pH 5.6 · ligands ACT, AZI, CA Ca2+-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with myosin IIA · MYOSIN-9 (chains Q) | unmapped |
| EV-PDB-2LNK-1 RCSB PDB | nmr_structure | structure | in vitro · 39.85 °C · pH 6.1 Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA · Myosin heavy chain, non-muscle IIa (chains C) | unmapped |
| EV-BMRB-18169 BMRB | nmr_shifts | chemical_shift | in vitro · 39.85 °C · pH 6.1 Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-25208 BMRB | nmr_shifts | chemical_shift | in vitro · 26.85 °C · pH 6 Backbone and Side Chain Chemical Shift Assignments for S100A4dC in complex with MPT · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-25992 BMRB | nmr_shifts | chemical_shift | in vitro · 9.85 °C · pH 6.2 Backbone and Side Chain Chemical Shift Assignments for the myosin IIA fragment 1893-1937 (MPT) · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-AFDB-AF-P35579-F1 AlphaFold DB | af_prediction | plddt: 76.19 pLDDT | in silico AlphaFold DB prediction AF-P35579-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-1960 | unmapped |
| EV-SMASH-SMFS-000078 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.2 Differential activity of nonmuscle myosin IIA and IIB isoforms generates a dynamic actomyosin network in a concentration-dependent manner. · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000108 SMASH-BIO | force_spectroscopy | study_record | in vitro Force transmission in an actomyosin cytoskeletal network revealed by particle fluctuation analysis. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000113 SMASH-BIO | force_spectroscopy | study_record | in vitro Force-modulated structural landscape of the catch bonding F-actin crosslinker α-actinin-4 · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000161 SMASH-BIO | force_spectroscopy | study_record | in cell · pH 8 Leader cell myosin 10 controls adhesion dynamics, invasion, and EMT pathway activation. · Myosin; tension sensors; experiment class: force_generation_motor, nucleic_acid_protein_interaction, receptor_ligand_adhesion, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-000184 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Mechanics of blunting of actin-myosin interaction dynamics by the actinopathy-causing mutation E334Q in cytoskeletal γ-actin. · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization | unmapped |
| EV-SMASH-SMFS-000198 SMASH-BIO | force_spectroscopy | study_record | in vitro Molecular mechanics of smooth muscle contraction and relaxation modulated by caldesmon · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000199 SMASH-BIO | force_spectroscopy | study_record | in cell Molecular tension tether based on electrochemiluminescence sensor for cellular mechanics measurement. · Myosin; tension sensors; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000201 SMASH-BIO | force_spectroscopy | study_record | in vitro Motor Occupancy Defines Emergent Mechanical States in Cardiac Myosin Ensembles · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000210 SMASH-BIO | force_spectroscopy | study_record | in vitro Myotropes unveil two myosin cycles with distinct kinetics and stroke size · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000288 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule analysis sheds light on cardiac myosin dysfunction due to hypertrophic cardiomyopathy mutation A57D in ventricular myosin light chain-1 (MLC1v) · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-000305 SMASH-BIO | force_spectroscopy | study_record | in vitro State-dependent energy conversion produces degenerate dissipation in active actomyosin networks · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000327 SMASH-BIO | force_spectroscopy | study_record | in vitro The hypertrophic cardiomyopathy mutation G768R makes cardiac myosin a high duty ratio motor · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000333 SMASH-BIO | force_spectroscopy | study_record | in vitro The role of organelles as mechanotransducers. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000337 SMASH-BIO | force_spectroscopy | study_record | in vitro Traction force generation in Plasmodium sporozoites is modulated by a surface adhesin. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000349 SMASH-BIO | force_spectroscopy | study_record | in vitro α5β1 and αvβ3 integrins employ two distinct adhesion strengthening modes to respond to fibronectin stiffness within seconds of initiating adhesion · Myosin II; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000372 SMASH-BIO | force_spectroscopy | study_record | in vitro Actin contractility and endocytosis create apico-basal tension gradient in HeLa cells · Myosin; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, nucleic_acid_protein_interaction, rheology_cell | unmapped |
| EV-SMASH-SMFS-000393 SMASH-BIO | force_spectroscopy | study_record | in vitro Biophysical and Structural Features of αβT-Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T-Cell Activation. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-000489 SMASH-BIO | force_spectroscopy | study_record | in vitro Load-dependent RGD-context sensing via αV-class integrin reprograms cellular adhesion and mechanics within seconds · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000500 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 5 Measuring emergent mechanical changes in cytoskeletal ensembles in vitro using QCM-D. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-000509 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanically-induced remodeling of the cell surface generates actin-rich protrusions resembling tunneling nanotubes · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000519 SMASH-BIO | force_spectroscopy | study_record | in vitro Modulation of striated-muscle contractility by a high-affinity myosin-targeting peptide. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-000524 SMASH-BIO | force_spectroscopy | study_record | in vitro Motor-driven modulation of actin network mechanics across linear and nonlinear regimes · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000564 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing protein-protein interactions with drag flow: A case study of F-actin and tropomyosin · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-000565 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing protein-protein interactions with drag flow: a case study of F-actin and tropomyosin. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-000594 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000595 SMASH-BIO | force_spectroscopy | study_record | in vitro S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: application to the study of human β-cardiac myosin · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000623 SMASH-BIO | force_spectroscopy | study_record | in vitro Stall force measurement of the kinesin-3 motor KIF1A using a programmable DNA origami nanospring · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000640 SMASH-BIO | force_spectroscopy | study_record | in vitro The Z-disc protein α-actinin-2 forms a force-activated, directional bond with F-actin · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-000668 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 ATP-induced reconfiguration of the micro-viscoelasticity of cardiac and skeletal myosin solutions. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-000731 SMASH-BIO | force_spectroscopy | study_record | in cell · pH 7.4 Develop Tandem Tension Sensor to Gauge Integrin-Transmitted Molecular Forces. · Myosin; tension sensors; experiment class: force_generation_motor, nucleic_acid_mechanics, receptor_ligand_adhesion, rheology_cell, unfolding_nucleic_acid | unmapped |
| EV-SMASH-SMFS-000792 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000853 SMASH-BIO | force_spectroscopy | study_record | in vitro Modeling thick filament activation suggests a molecular basis for force depression. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-000860 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000864 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Myosin-induced F-actin fragmentation facilitates contraction of actin networks. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000876 SMASH-BIO | force_spectroscopy | study_record | in vitro One must reconstitute the functions of interest from purified proteins. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000938 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Single-Molecule Investigation of Load-Dependent Actomyosin Dissociation Kinetics for Cardiac and Slow Skeletal Myosin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-000944 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule force spectroscopy reveals intra- and intermolecular interactions of Caenorhabditis elegans HMP-1 during mechanotransduction. · Myosin; magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-000974 SMASH-BIO | force_spectroscopy | study_record | in vitro Tension-induced adhesion mode switching: the interplay between focal adhesions and clathrin-containing adhesion complexes · Myosin; afm smfs; experiment class: force_generation_motor, membrane_mechanics, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000999 SMASH-BIO | force_spectroscopy | study_record | in vitro Traction force generation in motile malaria parasites is modulated by the Plasmodium adhesin TLP · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001025 SMASH-BIO | force_spectroscopy | study_record | in vitro α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, force_generation_polymerization, nucleic_acid_protein_interaction, receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001075 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Cell protrusions and contractions generate long-range membrane tension propagation. · Myosin; optical tweezers; experiment class: force_generation_motor, membrane_mechanics | unmapped |
| EV-SMASH-SMFS-001153 SMASH-BIO | force_spectroscopy | study_record | in cell Exploring Mechanical Responses of Cells to Geometric Information Using Micropatterned DNA-Based Molecular Tension Probes. · Myosin; tension sensors; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001173 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. · Myosin; afm smfs; experiment class: force_generation_motor, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-001179 SMASH-BIO | force_spectroscopy | study_record | in vitro Homologous mutations in β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001184 SMASH-BIO | force_spectroscopy | study_record | in vitro Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes. · Myosin; optical tweezers; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001200 SMASH-BIO | force_spectroscopy | study_record | in cell · pH 7 Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton. · Myosin; tension sensors; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001209 SMASH-BIO | force_spectroscopy | study_record | in vitro Kindlin stabilizes the talin·integrin bond under mechanical load by generating an ideal bond. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001241 SMASH-BIO | force_spectroscopy | study_record | in vitro Modeling Thick Filament Activation Suggests a Molecular Basis for Force Depression · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001245 SMASH-BIO | force_spectroscopy | study_record | in vitro Motor-free contractility of active biopolymer networks. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001266 SMASH-BIO | force_spectroscopy | study_record | in cell Optimal cell traction forces in a generalized motor-clutch model. · Myosin; tension sensors; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001310 SMASH-BIO | force_spectroscopy | study_record | in vitro Single Molecule Mechanics and Kinetics of Cardiac Myosin Interacting with Regulated Thin Filaments · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001323 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule mechanics and kinetics of cardiac myosin interacting with regulated thin filaments. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001357 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 6 The weakness of senescent dermal fibroblasts. · Myosin II; afm smfs; experiment class: force_generation_motor, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-001358 SMASH-BIO | force_spectroscopy | study_record | in vitro Theory of sarcomere assembly inferred from sequential ordering of myofibril components · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001362-r0 SMASH-BIO | force_spectroscopy | persistence_length: 10 µm | in vitro · pH 7 Twist response of actin filaments. · Myosin; magnetic tweezers; experiment class: force_generation_motor, nucleic_acid_mechanics | unmapped |
| EV-SMASH-SMFS-001380 SMASH-BIO | force_spectroscopy | study_record | in cell “Optimality of motor and clutch mechanical properties in a generalized model for cell traction forces” · Myosin; tension sensors; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001407 SMASH-BIO | force_spectroscopy | study_record | in vitro Analysis of the polar residues located at the head domain of focal adhesion protein vinculin under the presence of the Shigella effector IpaA and its possible implications during in vivo mechanotransduction · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001433 SMASH-BIO | force_spectroscopy | study_record | in vitro Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemo-mechanical properties despite the same myosin heavy chain isoform · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001434 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemomechanical properties despite bearing the same myosin heavy chain isoform. · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001437 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 6.8 Catching the Conformational Wave: Measuring the Working Strokes of Protofilaments as They Curl Outward from Disassembling Microtubule Tips. · Myosin; optical tweezers; experiment class: chromatin_mechanics, force_generation_motor | unmapped |
| EV-SMASH-SMFS-001490-r0 SMASH-BIO | force_spectroscopy | step_size: 8 nm | in vitro Effect of varying load in moving period of a step on dynamics of molecular motors. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001490-r1 SMASH-BIO | force_spectroscopy | step_size: 36 nm | in vitro Effect of varying load in moving period of a step on dynamics of molecular motors. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001519 SMASH-BIO | force_spectroscopy | study_record | in vitro Force measurements of Myosin II waves at the yolk surface during Drosophila dorsal closure. · Myosin; magnetic tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001537 SMASH-BIO | force_spectroscopy | study_record | in vitro High Sensitivity Top-down Proteomics Captures Single Muscle Cell Heterogeneity in Large Proteoforms · Myosin; afm smfs; experiment class: force_generation_motor, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-001550 SMASH-BIO | force_spectroscopy | study_record | in vitro Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes · Myosin; optical tweezers; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001607 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Microtubule Dumbbells to Assess the Effect of Force Geometry on Single Kinesin Motors. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001620 SMASH-BIO | force_spectroscopy | study_record | in vitro Molecular-level evidence of force maintenance by smooth muscle myosin during LC20 dephosphorylation. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001632 SMASH-BIO | force_spectroscopy | study_record | in vitro Myosin II Adjusts Motility Properties and Regulates Force Production Based on Motor Environment. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001670 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing Myosin Ensemble Mechanics in Actin Filament Bundles using Optical Tweezers. · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001712 SMASH-BIO | force_spectroscopy | study_record | in cell Single-Molecule Force Imaging Reveals That Podosome Formation Requires No Extracellular Integrin-Ligand Tensions or Interactions. · Myosin; tension sensors; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001775 SMASH-BIO | force_spectroscopy | study_record | in vitro Two-point optical manipulation reveals mechanosensitive remodeling of cell-cell contacts in vivo · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001805 SMASH-BIO | force_spectroscopy | study_record | in vitro A reverse stroke characterizes the force generation of cardiac myofilaments, leading to an understanding of heart function. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001843 SMASH-BIO | force_spectroscopy | study_record | in vitro Cell mechanical properties of human breast carcinoma cells depend on temperature. · Myosin; magnetic tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001853 SMASH-BIO | force_spectroscopy | study_record | in vitro Computational Tool for Ensemble Averaging of Single-Molecule Data. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001858 SMASH-BIO | force_spectroscopy | study_record | in vitro Contribution of cytoplasm viscoelastic properties to mitotic spindle positioning · Myosin; magnetic tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-001901 SMASH-BIO | force_spectroscopy | study_record | in vitro Effective cell membrane tension is independent of polyacrylamide substrate stiffness · Myosin II; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001951 SMASH-BIO | force_spectroscopy | study_record | in vitro Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM-based single-cell force spectroscopy. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001957 SMASH-BIO | force_spectroscopy | study_record | in vitro Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001962 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Immobilization of Jagged1 Enhances Vascular Smooth Muscle Cells Maturation by Activating the Notch Pathway. · Myosin; magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-002024 SMASH-BIO | force_spectroscopy | study_record | in vitro Motor-Driven Restructuring of Cytoskeleton Composites Leads to Tunable Time-Varying Elasticity. · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-002033 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.2 Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002039 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.2 Nanomechanical Phenotypes in Cardiac Myosin-Binding Protein C Mutants That Cause Hypertrophic Cardiomyopathy. · Myosin; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002106 SMASH-BIO | force_spectroscopy | study_record | in vitro Recent insights into the relative timing of myosin's powerstroke and release of phosphate. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002213 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 A Myosin II-Based Nanomachine Devised for the Study of Ca2+-Dependent Mechanisms of Muscle Regulation. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002221 SMASH-BIO | force_spectroscopy | study_record | in vitro A function of profilin in force generation during malaria parasite motility that is independent of actin binding. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002223 SMASH-BIO | force_spectroscopy | study_record | in vitro A myosin II-based nanomachine devised for the study of Ca 2+ -dependent mechanisms of muscle regulation · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002228 SMASH-BIO | force_spectroscopy | study_record | in vitro Acto-Myosin Cross-Bridge Stiffness Depends on the Nucleotide State of Myosin II. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002229 SMASH-BIO | force_spectroscopy | study_record | in vitro Acto-myosin cross-bridge stiffness depends on the nucleotide state of the myosin II · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002273 SMASH-BIO | force_spectroscopy | study_record | in vitro Collective Force Generation by Molecular Motors Is Determined by Strain-Induced Unbinding. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-002274 SMASH-BIO | force_spectroscopy | study_record | in vitro Collective intracellular cargo transport by multiple kinesins on multiple microtubules. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-002275 SMASH-BIO | force_spectroscopy | study_record | in vitro Computational Tool for Ensemble Averaging of Single-Molecule Data · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002280 SMASH-BIO | force_spectroscopy | study_record | in vitro Contracting striated muscle has a dynamic I-band spring with an undamped stiffness 100 times larger than the passive stiffness. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-002301 SMASH-BIO | force_spectroscopy | study_record | in vitro Different Vinculin Binding Sites Use the Same Mechanism to Regulate Directional Force Transduction. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002311 SMASH-BIO | force_spectroscopy | study_record | in vitro Dynamic actin cross-linking governs the cytoplasm's transition to fluid-like behavior. · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-002314 SMASH-BIO | force_spectroscopy | study_record | in vitro Dynamics of ATP-dependent and ATP-independent steppings of myosin-V on actin: catch-bond characteristics. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002378 SMASH-BIO | force_spectroscopy | study_record | in vitro Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM based SCFS · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002381 SMASH-BIO | force_spectroscopy | study_record | in vitro Human hypertrophic cardiomyopathy mutation R712L suppresses the working stroke of cardiac myosin and can be rescued by omecamtiv mecarbil · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002383 SMASH-BIO | force_spectroscopy | study_record | in vitro Hypertrophic cardiomyopathy ß-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super-relaxed state · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-002446 SMASH-BIO | force_spectroscopy | study_record | in vitro Molecular mechanism for direct actin force-sensing by α-catenin · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002447 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 Molecular mechanism for direct actin force-sensing by α-catenin. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002448 SMASH-BIO | force_spectroscopy | study_record | in vitro Motor-Free Contractility in Active Gels. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002456 SMASH-BIO | force_spectroscopy | study_record | in vitro Myosin from the ventricle is more sensitive to omecamtiv mecarbil than myosin from the atrium. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002459 SMASH-BIO | force_spectroscopy | study_record | in vitro Nanomechanical phenotypes in cMyBP-C mutants that cause hypertrophic cardiomyopathy · Myosin; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002485 SMASH-BIO | force_spectroscopy | study_record | in vitro Patient-derived glioblastoma cells (GBM) exhibit distinct biomechanical profiles associated with altered activity in the cytoskeleton regulatory pathway · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-002519 SMASH-BIO | force_spectroscopy | study_record | in vitro Single molecule analysis reveals the role of regulatory light chains in fine-tuning skeletal myosin-II function · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002534 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule analysis reveals that regulatory light chains fine-tune skeletal myosin II function. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002606 SMASH-BIO | force_spectroscopy | study_record | in cell A Molecular Tension Sensor for N-Cadherin Reveals Distinct Forms of Mechanosensitive Adhesion Assembly in Adherens and Synaptic Junctions · Myosin II; tension sensors; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-002613 SMASH-BIO | force_spectroscopy | study_record | in vitro A model for the chemomechanical coupling of myosin-V molecular motors. · Myosin; afm smfs; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002655 SMASH-BIO | force_spectroscopy | study_record | in vitro Cardiomyopathy-associated mutations in tropomyosin differently affect actin-myosin interaction at single-molecule and ensemble levels. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002696 SMASH-BIO | force_spectroscopy | study_record | in vitro Dynamic actin crosslinking governs the cytoplasm’s transition to fluid-like behavior · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-002737 SMASH-BIO | force_spectroscopy | study_record | in vitro Functional significance of HCM mutants of tropomyosin, V95A and D175N, studied with in vitro motility assays. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002880 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Role of a Kinesin Motor in Cancer Cell Mechanics. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-002881 SMASH-BIO | force_spectroscopy | study_record | in vitro Role of a kinesin motor in cancer cell mechanics · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-002892 SMASH-BIO | force_spectroscopy | study_record | in vitro Single molecule mechanics resolves the earliest events in force generation by cardiac myosin · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002893 SMASH-BIO | force_spectroscopy | study_record | in vitro Single molecule mechanics resolves the earliest events in force generation by cardiac myosin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002916 SMASH-BIO | force_spectroscopy | study_record | in vitro Structural and mechanistic insights into mechanoactivation of focal adhesion kinase. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002955 SMASH-BIO | force_spectroscopy | study_record | in vitro Transformation of the Nonprocessive Fast Skeletal Myosin II into a Processive Motor. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002961 SMASH-BIO | force_spectroscopy | study_record | in vitro Ultra-fast force-clamp spectroscopy data on the interaction between skeletal muscle myosin and actin. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002991 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Acidosis affects muscle contraction by slowing the rates myosin attaches to and detaches from actin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-002992 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Acidosis and Phosphate Directly Reduce Myosin's Force-Generating Capacity Through Distinct Molecular Mechanisms. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003015 SMASH-BIO | force_spectroscopy | study_record | in vitro Cadherin-11 promotes neural crest cell spreading by reducing intracellular tension-Mapping adhesion and mechanics in neural crest explants by atomic force microscopy. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-003020 SMASH-BIO | force_spectroscopy | study_record | in vitro Carbonylation of atrial myosin prolongs its interaction with actin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003055 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003063 SMASH-BIO | force_spectroscopy | study_record | in vitro Determining Stable Single Alpha Helical (SAH) Domain Properties by Circular Dichroism and Atomic Force Microscopy. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003075-r0 SMASH-BIO | force_spectroscopy | molecular_stiffness: 2 pN/nm | in vitro Do Actomyosin Single-Molecule Mechanics Data Predict Mechanics of Contracting Muscle? · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-003091 SMASH-BIO | force_spectroscopy | study_record | in vitro Electro-optic deflectors deliver advantages over acousto-optical deflectors in a high resolution, ultra-fast force-clamp optical trap. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003095 SMASH-BIO | force_spectroscopy | study_record | in vitro Estimation of actomyosin active force maintained by tropomyosin and troponin complex under vertical forces in the in vitro motility assay system. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-003126 SMASH-BIO | force_spectroscopy | study_record | in vitro High-Speed Optical Tweezers for the Study of Single Molecular Motors. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003223 SMASH-BIO | force_spectroscopy | study_record | in vitro PLANT: A Method for Detecting Changes of Slope in Noisy Trajectories. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003332 SMASH-BIO | force_spectroscopy | study_record | in vitro The Mechanical Power of Protein Folding · Myosin; magnetic tweezers; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-003337 SMASH-BIO | force_spectroscopy | study_record | in vitro The Work of Titin Protein Folding as a Major Driver in Muscle Contraction. · Myosin; magnetic tweezers; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-003351 SMASH-BIO | force_spectroscopy | study_record | in vitro Thick-Filament Extensibility in Intact Skeletal Muscle. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-003377 SMASH-BIO | force_spectroscopy | study_record | in vitro Whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, force_generation_polymerization, unfolding_protein | unmapped |
| EV-SMASH-SMFS-003409 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 6.8 Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy. · Myosin II; acoustic force spectroscopy; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-003447 SMASH-BIO | force_spectroscopy | study_record | in vitro Cooperativity of myosin interaction with thin filaments is enhanced by stabilizing substitutions in tropomyosin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003483 SMASH-BIO | force_spectroscopy | study_record | in vitro Effects of cytoskeletal drugs on actin cortex elasticity. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, membrane_mechanics, rheology_cell | unmapped |
| EV-SMASH-SMFS-003508 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices. · Myosin; magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-003513 SMASH-BIO | force_spectroscopy | study_record | in vitro Force Spectroscopy with 9-μs Resolution and Sub-pN Stability by Tailoring AFM Cantilever Geometry. · Myosin; afm smfs; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003514 SMASH-BIO | force_spectroscopy | study_record | in vitro Force dependence of filopodia adhesion: involvement of myosin II and formins · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003539 SMASH-BIO | force_spectroscopy | study_record | in vitro How to Measure Load-Dependent Kinetics of Individual Motor Molecules Without a Force-Clamp. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003549 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 Increasing evidence of mechanical force as a functional regulator in smooth muscle myosin light chain kinase. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003574 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003606 SMASH-BIO | force_spectroscopy | study_record | in cell Multiplexing molecular tension sensors reveals piconewton force gradient across talin-1. · Myosin; tension sensors; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003639 SMASH-BIO | force_spectroscopy | study_record | in vitro Phenomenological and microscopic theories for catch bonds. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003652 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing cytoskeletal pre-stress and nuclear mechanics in endothelial cells with spatiotemporally controlled (de-)adhesion kinetics on micropatterned substrates. · Myosin; magnetic tweezers; experiment class: chromatin_mechanics, force_generation_motor, receptor_ligand_adhesion, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-003686 SMASH-BIO | force_spectroscopy | study_record | in vitro Simulating the dynamics of the mechanochemical cycle of myosin-V. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003739 SMASH-BIO | force_spectroscopy | study_record | in vitro Structural Modeling of Mechanosensitivity in Non-Muscle Cells: Multiscale Approach to Understand Cell Sensing. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003751 SMASH-BIO | force_spectroscopy | study_record | in vitro Tension-Dependent Stretching Activates ZO-1 to Control the Junctional Localization of Its Interactors. · Myosin; magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-003752 SMASH-BIO | force_spectroscopy | study_record | in vitro Tension-dependent stretching and folding of ZO-1 controls the localization of its interactors · Myosin; magnetic tweezers; experiment class: force_generation_motor, translation_transcription_replication, unfolding_protein | unmapped |
| EV-SMASH-SMFS-003789 SMASH-BIO | force_spectroscopy | study_record | in vitro Viscoelastic Dissipation Stabilizes Cell Shape Changes during Tissue Morphogenesis. · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-003790 SMASH-BIO | force_spectroscopy | study_record | in vitro Viscoelastic dissipation stabilizes cell shape changes during tissue morphogenesis · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-003796 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003812 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Actomyosin Cortical Mechanical Properties in Nonadherent Cells Determined by Atomic Force Microscopy. · Myosin II; afm smfs; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-003835 SMASH-BIO | force_spectroscopy | study_record | in vitro Cells Sensing Mechanical Cues: Stiffness Influences the Lifetime of Cell-Extracellular Matrix Interactions by Affecting the Loading Rate. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-003849 SMASH-BIO | force_spectroscopy | study_record | in vitro Coupling of Retrograde Flow to Force Production During Malaria Parasite Migration. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003868 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Direct observation of the actin filament by tip-scan atomic force microscopy. · Myosin; afm smfs; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-003933 SMASH-BIO | force_spectroscopy | study_record | in cell · pH 7.6 Integrins outside focal adhesions transmit tensions during stable cell adhesion. · Myosin II; tension sensors; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003979 SMASH-BIO | force_spectroscopy | study_record | in vitro Muscle Fatigue from the Perspective of a Single Crossbridge. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004000 SMASH-BIO | force_spectroscopy | study_record | in vitro Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004034 SMASH-BIO | force_spectroscopy | study_record | in vitro Role of catch bonds in actomyosin mechanics and cell mechanosensitivity. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004215 SMASH-BIO | force_spectroscopy | study_record | in cell FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis. · Myosin; tension sensors; experiment class: force_generation_motor, nucleic_acid_protein_interaction, rheology_cell | unmapped |
| EV-SMASH-SMFS-004221 SMASH-BIO | force_spectroscopy | study_record | in vitro Force fluctuations in three-dimensional suspended fibroblasts. · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-004232 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 Harmonic force spectroscopy measures load-dependent kinetics of individual human β-cardiac myosin molecules. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004252 SMASH-BIO | force_spectroscopy | study_record | in cell Integrin Molecular Tension within Motile Focal Adhesions. · Myosin; tension sensors; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004256 SMASH-BIO | force_spectroscopy | study_record | in vitro Intracellular and extracellular forces drive primary cilia movement. · Myosin; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-004263 SMASH-BIO | force_spectroscopy | study_record | in vitro Isoforms Confer Characteristic Force Generation and Mechanosensation by Myosin II Filaments. · Myosin II; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004288 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanics of Vascular Smooth Muscle. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-004344 SMASH-BIO | force_spectroscopy | study_record | in vitro Quantitating membrane bleb stiffness using AFM force spectroscopy and an optical sideview setup. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-004382 SMASH-BIO | force_spectroscopy | study_record | in vitro Stabilizing the central part of tropomyosin increases the bending stiffness of the thin filament. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004408 SMASH-BIO | force_spectroscopy | study_record | in vitro The lifetime of the actomyosin complex in vitro under load corresponding to stretch of contracting muscle. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004413 SMASH-BIO | force_spectroscopy | study_record | in vitro The role of myosin-II in force generation of DRG filopodia and lamellipodia. · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-004481 SMASH-BIO | force_spectroscopy | study_record | in vitro Catch-bond behaviour facilitates membrane tubulation by non-processive myosin 1b. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, membrane_mechanics, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004504 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Cytoplasmic dynein transports cargos via load-sharing between the heads. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-004552 SMASH-BIO | force_spectroscopy | study_record | in vitro Force-dependent conformational switch of α-catenin controls vinculin binding. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-004574 SMASH-BIO | force_spectroscopy | study_record | in vitro Inherent force-dependent properties of β-cardiac myosin contribute to the force-velocity relationship of cardiac muscle. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004593 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Loop 2 of myosin is a force-dependent inhibitor of the rigor bond. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004611 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical role of actin dynamics in the rheology of the Golgi complex and in Golgi-associated trafficking events. · Myosin II; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, rheology_cell | unmapped |
| EV-SMASH-SMFS-004628 SMASH-BIO | force_spectroscopy | study_record | in vitro Molecular mechanism regulating myosin and cardiac functions by ELC. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-004635-r0 SMASH-BIO | force_spectroscopy | velocity: 310 nm/s | in vitro Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004662 SMASH-BIO | force_spectroscopy | study_record | in vitro Plasticity of hydrogen bond networks regulates mechanochemistry of cell adhesion complexes. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004679 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Reconstituting the motility of isolated intracellular cargoes. · Myosin; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, nucleic_acid_protein_interaction, rheology_cell | unmapped |
| EV-SMASH-SMFS-004714 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Stable single α-helices are constant force springs in proteins. · Myosin; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-004733 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004735 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 The role of caldesmon and its phosphorylation by ERK on the binding force of unphosphorylated myosin to actin. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004751 SMASH-BIO | force_spectroscopy | study_record | in vitro UNC-45B chaperone: the role of its domains in the interaction with the myosin motor domain. · Myosin II; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-004761 SMASH-BIO | force_spectroscopy | study_record | in vitro [Analysis of mechanochemical dynamics of actomyosin interactions revealed by single molecule optical trap microscope]. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004827 SMASH-BIO | force_spectroscopy | study_record | in vitro Cross-species mechanical fingerprinting of cardiac myosin binding protein-C. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-004844 SMASH-BIO | force_spectroscopy | study_record | in vitro Direct observation of phosphate inhibiting the force-generating capacity of a miniensemble of Myosin molecules. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-004856 SMASH-BIO | force_spectroscopy | study_record | in vitro Elastic coupling of nascent apCAM adhesions to flowing actin networks. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004870 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Force spectroscopy measurements show that cortical neurons exposed to excitotoxic agonists stiffen before showing evidence of bleb damage. · Myosin; afm smfs; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-004898 SMASH-BIO | force_spectroscopy | study_record | in vitro Kinetic characterization of nonmuscle myosin IIb at the single molecule level. · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-004920 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.2 Measuring forces at the leading edge: a force assay for cell motility. · Myosin; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, rheology_cell | unmapped |
| EV-SMASH-SMFS-004948 SMASH-BIO | force_spectroscopy | study_record | in vitro Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005006 SMASH-BIO | force_spectroscopy | study_record | in vitro Regulatory light chain mutants linked to heart disease modify the cardiac myosin lever arm. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-005046 SMASH-BIO | force_spectroscopy | study_record | in vitro Stochastic dynamics of small ensembles of non-processive molecular motors: the parallel cluster model. · Myosin II; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005081 SMASH-BIO | force_spectroscopy | study_record | in vitro Unphosphorylated calponin enhances the binding force of unphosphorylated myosin to actin. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005083 SMASH-BIO | force_spectroscopy | study_record | in vitro Unraveling the nanoscale surface properties of chitin synthase mutants of Aspergillus fumigatus and their biological implications. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005168 SMASH-BIO | force_spectroscopy | study_record | in cell E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch. · Myosin; tension sensors; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005200 SMASH-BIO | force_spectroscopy | study_record | in vitro Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005243 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical and kinetic properties of β-cardiac/slow skeletal muscle myosin. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-005309 SMASH-BIO | force_spectroscopy | study_record | in vitro Recent insights into muscle fatigue at the cross-bridge level. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005310 SMASH-BIO | force_spectroscopy | study_record | in vitro Recent insights into the molecular basis of muscular fatigue. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005358 SMASH-BIO | force_spectroscopy | study_record | in vitro Switching of myosin-V motion between the lever-arm swing and brownian search-and-catch. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005379 SMASH-BIO | force_spectroscopy | study_record | in vitro Tracking UNC-45 chaperone-myosin interaction with a titin mechanical reporter. · Myosin; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005383 SMASH-BIO | force_spectroscopy | study_record | in vitro Two independent switches regulate cytoplasmic dynein's processivity and directionality. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-005384 SMASH-BIO | force_spectroscopy | study_record | in vitro Ultrafast force-clamp spectroscopy of single molecules reveals load dependence of myosin working stroke. · Myosin; optical tweezers; experiment class: force_generation_motor, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-005435 SMASH-BIO | force_spectroscopy | study_record | in vitro Attachment of anti-GFP antibodies to microspheres for optical trapping experiments. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005450 SMASH-BIO | force_spectroscopy | study_record | in vitro Cancer cells regulate biomechanical properties of human microvascular endothelial cells. · Myosin; magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005466 SMASH-BIO | force_spectroscopy | study_record | in vitro Cytoskeletal protein kinases: titin and its relations in mechanosensing. · Myosin; afm smfs; experiment class: force_generation_motor, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005481 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.2 Drosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering properties. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005509 SMASH-BIO | force_spectroscopy | study_record | in vitro Force spectroscopy reveals multiple "closed states" of the muscle thin filament. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005520 SMASH-BIO | force_spectroscopy | study_record | in vitro Glomerular podocytes: a study of mechanical properties and mechano-chemical signaling. · Myosin; magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005550 SMASH-BIO | force_spectroscopy | study_record | in vitro Mapping the classical cross-bridge theory and backward steps in a three bead laser trap setup. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005561 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. · Myosin II; magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005563 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical unfolding of cardiac myosin binding protein-C by atomic force microscopy. · Myosin; afm smfs; experiment class: force_generation_motor, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005594 SMASH-BIO | force_spectroscopy | study_record | in vitro On the mechanical stabilization of filopodia. · Myosin; magnetic tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-005599 SMASH-BIO | force_spectroscopy | study_record | in vitro Optical traps to study properties of molecular motors. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005625 SMASH-BIO | force_spectroscopy | study_record | in vitro Quasiperiodic distribution of rigor cross-bridges along a reconstituted thin filament in a skeletal myofibril. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005678 SMASH-BIO | force_spectroscopy | study_record | in vitro The elementary events underlying force generation in neuronal lamellipodia. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005681 SMASH-BIO | force_spectroscopy | study_record | in vitro The optical trapping dumbbell assay for nonprocessive motors or motors that turn around filaments. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005690 SMASH-BIO | force_spectroscopy | study_record | in vitro Using optical tweezers to study the fine details of myosin ATPase mechanochemical cycle. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005702 SMASH-BIO | force_spectroscopy | study_record | in vitro A model for processive movement of single-headed myosin-IX. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005710 SMASH-BIO | force_spectroscopy | study_record | in vitro Actin and myosin regulate cytoplasm stiffness in plant cells: a study using optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-005747 SMASH-BIO | force_spectroscopy | study_record | in vitro Complex fluids: probing mechanical properties of biological systems with optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, membrane_mechanics, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005767 SMASH-BIO | force_spectroscopy | study_record | in vitro Direct observation of the myosin-Va power stroke and its reversal. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-005812 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitro. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005818 SMASH-BIO | force_spectroscopy | study_record | in vitro Insights into the mechanisms of myosin and kinesin molecular motors from the single-molecule unbinding force measurements. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005839 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.8 Mechanical characterization of one-headed myosin-V using optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005840 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical induction in embryonic development and tumor growth integrative cues through molecular to multicellular interplay and evolutionary perspectives. · Myosin; magnetic tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-005873 SMASH-BIO | force_spectroscopy | study_record | in vitro Nonlinear elasticity and an 8-nm working stroke of single myosin molecules in myofilaments. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005905 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.9 Self-assembly of three-dimensional prestressed tensegrity structures from DNA. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005912-r0 SMASH-BIO | force_spectroscopy | loading_rate: 1800 pN/s | in vitro Single-molecule adhesion forces and attachment lifetimes of myosin-I phosphoinositide interactions. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005916 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule dual-beam optical trap analysis of protein structure and function. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-005964-r0 SMASH-BIO | force_spectroscopy | step_size: 5.9 nm | in vitro Unconventional processive mechanics of non-muscle myosin IIB. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006014 SMASH-BIO | force_spectroscopy | study_record | in vitro Control of cell membrane tension by myosin-I. · Myosin; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006036 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Drug effect unveils inter-head cooperativity and strain-dependent ADP release in fast skeletal actomyosin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006106 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical stability and differentially conserved physical-chemical properties of titin Ig-domains. · Myosin; afm smfs; experiment class: force_generation_motor, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-006143 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Phosphorylation of tropomyosin extends cooperative binding of myosin beyond a single regulatory unit. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006169 SMASH-BIO | force_spectroscopy | study_record | in vitro Removal of the cardiac myosin regulatory light chain increases isometric force production. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006170 SMASH-BIO | force_spectroscopy | study_record | in vitro Reversal of the myosin power stroke induced by fast stretching of intact skeletal muscle fibers. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006177 SMASH-BIO | force_spectroscopy | study_record | in vitro Simultaneous measurement of nucleotide occupancy and mechanical displacement in myosin-V, a processive molecular motor. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006194 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule force spectroscopy distinguishes target binding modes of calmodulin. · Myosin; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-006203 SMASH-BIO | force_spectroscopy | study_record | in vitro Spatiotemporal analysis of cell response to a rigidity gradient: a quantitative study using multiple optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006205 SMASH-BIO | force_spectroscopy | study_record | in vitro Spontaneous oscillations of a minimal actomyosin system under elastic loading. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006265-r0 SMASH-BIO | force_spectroscopy | unbinding_force: 0.092 pN ± 0.022 | in vitro Affinity for MgADP and force of unbinding from actin of myosin purified from tonic and phasic smooth muscle. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006272 SMASH-BIO | force_spectroscopy | study_record | in vitro Biophysics of catch bonds. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006293 SMASH-BIO | force_spectroscopy | study_record | in vitro Cross-bridge induced force enhancement? · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006436 SMASH-BIO | force_spectroscopy | study_record | in vitro Response to Bianco et al.: Interaction forces between F-actin and titin PEVK domain measured with optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006460-r0 SMASH-BIO | force_spectroscopy | molecular_stiffness: 1.79 pN/nm | in vitro Single-molecule measurement of the stiffness of the rigor myosin head. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-006536 SMASH-BIO | force_spectroscopy | study_record | in vitro Characterization of actomyosin bond properties in intact skeletal muscle by force spectroscopy. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006600 SMASH-BIO | force_spectroscopy | study_record | in vitro Forced unfolding of coiled-coils in fibrinogen by single-molecule AFM. · Myosin; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-006649 SMASH-BIO | force_spectroscopy | study_record | in vitro Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006687 SMASH-BIO | force_spectroscopy | study_record | in vitro Revealing early steps of alpha2beta1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy. · Myosin; afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006740 SMASH-BIO | force_spectroscopy | study_record | in vitro A point mutation in the SH1 helix alters elasticity and thermal stability of myosin II. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006743 SMASH-BIO | force_spectroscopy | study_record | in vitro A unique mechanism for the processive movement of single-headed myosin-IX. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006756 SMASH-BIO | force_spectroscopy | study_record | in vitro Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006757-r0 SMASH-BIO | force_spectroscopy | stall_force: 1 pN | in vitro Cargo-binding makes a wild-type single-headed myosin-VI move processively. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, membrane_mechanics | unmapped |
| EV-SMASH-SMFS-006809 SMASH-BIO | force_spectroscopy | study_record | in vitro Force generation in single conventional actomyosin complexes under high dynamic load. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006821 SMASH-BIO | force_spectroscopy | study_record | in vitro Functional studies of individual myosin molecules. · Myosin II; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-006827 SMASH-BIO | force_spectroscopy | study_record | in vitro Interaction of non-adherent suspended neutrophils to complement opsonized pathogens: a new assay using optical traps. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006843 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical strength of sarcomere structures of skeletal myofibrils studied by submicromanipulation. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006848 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contraction. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006862 SMASH-BIO | force_spectroscopy | study_record | in vitro New techniques in linear and non-linear laser optics in muscle research. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006883 SMASH-BIO | force_spectroscopy | study_record | in vitro Reconciling the working strokes of a single head of skeletal muscle myosin estimated from laser-trap experiments and crystal structures. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006910 SMASH-BIO | force_spectroscopy | study_record | in vitro Strain-dependent kinetics of the myosin working stroke, and how they could be probed with optical-trap experiments. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006915 SMASH-BIO | force_spectroscopy | study_record | in vitro Temperature change does not affect force between regulated actin filaments and heavy meromyosin in single-molecule experiments. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006937 SMASH-BIO | force_spectroscopy | study_record | in vitro A new muscle contractile system composed of a thick filament lattice and a single actin filament. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006940 SMASH-BIO | force_spectroscopy | study_record | in vitro Acto-myosin cytoskeleton dependent viscosity and shear-thinning behavior of the amoeba cytoplasm. · Myosin II; magnetic tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-006987-r0 SMASH-BIO | force_spectroscopy | step_size: 36 nm | in vitro Force-dependent stepping kinetics of myosin-V. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006987-r1 SMASH-BIO | force_spectroscopy | stall_force: 5 pN | in vitro Force-dependent stepping kinetics of myosin-V. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007010-r0 SMASH-BIO | force_spectroscopy | molecular_stiffness: 0.04 pN/nm | in vitro Mechanical properties of single myosin molecules probed with the photonic force microscope. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007066-r0 SMASH-BIO | force_spectroscopy | step_size: 5 nm | in vitro Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007067 SMASH-BIO | force_spectroscopy | study_record | in vitro Slip sliding away: load-dependence of velocity generated by skeletal muscle myosin molecules in the laser trap. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007076 SMASH-BIO | force_spectroscopy | study_record | in vitro The dissipative contribution of myosin II in the cytoskeleton dynamics of myoblasts. · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007080 SMASH-BIO | force_spectroscopy | study_record | in vitro The neck domain of myosin II primarily regulates the actomyosin kinetics, not the stepsize. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007083 SMASH-BIO | force_spectroscopy | study_record | in vitro Three-dimensional bead position histograms reveal single-molecule nanomechanics. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007084-r0 SMASH-BIO | force_spectroscopy | persistence_length: 0.3 nm ± 0.04 | in vitro Titin PEVK segment: charge-driven elasticity of the open and flexible polyampholyte. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007084-r1 SMASH-BIO | force_spectroscopy | persistence_length: 0.18 nm ± 0.03 | in vitro Titin PEVK segment: charge-driven elasticity of the open and flexible polyampholyte. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007099 SMASH-BIO | force_spectroscopy | study_record | in vitro A model of stereocilia adaptation based on single molecule mechanical studies of myosin I. · Myosin II; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007101 SMASH-BIO | force_spectroscopy | study_record | in vitro A one-headed class V myosin molecule develops multiple large (approximately 32-nm) steps successively. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007102 SMASH-BIO | force_spectroscopy | study_record | in vitro A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007135 SMASH-BIO | force_spectroscopy | study_record | in vitro Exploring molecular motors and switches at the single-molecule level. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007184 SMASH-BIO | force_spectroscopy | study_record | in vitro Repriming the actomyosin crossbridge cycle. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-007218 SMASH-BIO | force_spectroscopy | study_record | in vitro Towards bridging the gap from molecular forces to the movement of organisms. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-007223 SMASH-BIO | force_spectroscopy | study_record | in vitro Using optical tweezers to relate the chemical and mechanical cross-bridge cycles. · Myosin; optical tweezers; experiment class: force_generation_motor, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-007226-r0 SMASH-BIO | force_spectroscopy | step_size: 19 nm | in vitro A kinetic mechanism for the fast movement of Chara myosin. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007228 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 A mutant heterodimeric myosin with one inactive head generates maximal displacement. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007237 SMASH-BIO | force_spectroscopy | study_record | in vitro Bio-nanomuscle project: contractile properties of single actin filaments in an A-band motility assay system. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007263 SMASH-BIO | force_spectroscopy | study_record | in vitro Higher plant myosin XI moves processively on actin with 35 nm steps at high velocity. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007271 SMASH-BIO | force_spectroscopy | study_record | in vitro Load-dependent kinetics of force production by smooth muscle myosin measured with optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007285 SMASH-BIO | force_spectroscopy | study_record | in vitro Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin-myosin interaction. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007294-r0 SMASH-BIO | force_spectroscopy | velocity: 23 nm/s | in vitro Probing the cell peripheral movements by optical trapping technique. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-007294-r1 SMASH-BIO | force_spectroscopy | molecular_stiffness: 0.024 pN/nm | in vitro Probing the cell peripheral movements by optical trapping technique. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-007294-r2 SMASH-BIO | force_spectroscopy | molecular_stiffness: 0.09 pN/nm | in vitro Probing the cell peripheral movements by optical trapping technique. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-007307-r0 SMASH-BIO | force_spectroscopy | bond_lifetime: 1 s | in vitro Slow filament dynamics and viscoelasticity in entangled and active actin networks. · Myosin; magnetic tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-007312-r0 SMASH-BIO | force_spectroscopy | step_size: 7.3 nm ± 1 | in vitro The converter domain modulates kinetic properties of Drosophila myosin. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007317 SMASH-BIO | force_spectroscopy | study_record | in vitro The unique properties of tonic smooth muscle emerge from intrinsic as well as intermolecular behaviors of Myosin molecules. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007318 SMASH-BIO | force_spectroscopy | study_record | in vitro The working stroke upon myosin-nucleotide complexes binding to actin. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007326 SMASH-BIO | force_spectroscopy | study_record | in vitro [Optical tweezers in biology and medicine]. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007367 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical Properties of a Single-Headed Processive Motor, Inner-Arm Dynein Subspecies-c of ChlamydomonasStudied at the Single Molecule Level. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007377 SMASH-BIO | force_spectroscopy | study_record | in vitro Molecular motors: force and movement generated by single myosin II molecules. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007381 SMASH-BIO | force_spectroscopy | study_record | in vitro PEVK domain of titin: an entropic spring with actin-binding properties. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007394 SMASH-BIO | force_spectroscopy | study_record | in vitro Stochasticity of the step size in the force generating process due to a single myosin molecule. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007398 SMASH-BIO | force_spectroscopy | study_record | in vitro The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin molecules. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007402 SMASH-BIO | force_spectroscopy | study_record | in vitro The myosin power stroke. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007404 SMASH-BIO | force_spectroscopy | study_record | in vitro The size and the speed of the working stroke of muscle myosin and its dependence on the force. · Myosin II; force spectroscopy unspecified; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007406-r0 SMASH-BIO | force_spectroscopy | step_size: 5.3 nm | in vitro Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007414 SMASH-BIO | force_spectroscopy | study_record | in vitro A new dimension in retrograde flow: centripetal movement of engulfed particles. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-007415 SMASH-BIO | force_spectroscopy | study_record | in vitro Alternative exon-encoded regions of Drosophila myosin heavy chain modulate ATPase rates and actin sliding velocity. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007416 SMASH-BIO | force_spectroscopy | study_record | in vitro Analysis of single-molecule mechanical recordings: application to acto-myosin interactions. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007425 SMASH-BIO | force_spectroscopy | study_record | in vitro Dictyostelium cells' cytoplasm as an active viscoplastic body. · Myosin II; magnetic tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007469 SMASH-BIO | force_spectroscopy | study_record | in vitro An unexpectedly large working stroke from chymotryptic fragments of myosin II. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007472 SMASH-BIO | force_spectroscopy | study_record | in vitro Characterization of single actomyosin rigor bonds: load dependence of lifetime and mechanical properties. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007484 SMASH-BIO | force_spectroscopy | study_record | in vitro Force production by single kinesin motors. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-007486 SMASH-BIO | force_spectroscopy | study_record | in vitro Functional consequences of mutations in the smooth muscle myosin heavy chain at sites implicated in familial hypertrophic cardiomyopathy. · Myosin II; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007487 SMASH-BIO | force_spectroscopy | study_record | in vitro In vitro assays of processive myosin motors. · Myosin II; optical tweezers; experiment class: force_generation_motor, membrane_mechanics | unmapped |
| EV-SMASH-SMFS-007498 SMASH-BIO | force_spectroscopy | study_record | in vitro Muscle, myosin and single molecules. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007499 SMASH-BIO | force_spectroscopy | study_record | in vitro Myosin-V stepping kinetics: a molecular model for processivity. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007510 SMASH-BIO | force_spectroscopy | study_record | in vitro R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007528 SMASH-BIO | force_spectroscopy | study_record | in vitro The light chain binding domain of expressed smooth muscle heavy meromyosin acts as a mechanical lever. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007539 SMASH-BIO | force_spectroscopy | study_record | in vitro Actin residue glu(93) is identified as an amino acid affecting myosin binding. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007552 SMASH-BIO | force_spectroscopy | study_record | in vitro Inner-arm dynein c of Chlamydomonas flagella is a single-headed processive motor. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007554 SMASH-BIO | force_spectroscopy | study_record | in vitro Kinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoforms. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007579 SMASH-BIO | force_spectroscopy | study_record | in vitro Two heads of myosin are better than one for generating force and motion. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007584 SMASH-BIO | force_spectroscopy | study_record | in vitro A 7-amino-acid insert in the heavy chain nucleotide binding loop alters the kinetics of smooth muscle myosin in the laser trap. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007597-r0 SMASH-BIO | force_spectroscopy | step_size: 8 nm ± 6 | in vitro Distribution of attachment events relative to actin binding sites as evidenced in a bidirectional actomyosin interaction model. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007601 SMASH-BIO | force_spectroscopy | study_record | in vitro Force and velocity measured for single molecules of RNA polymerase. · Myosin; optical tweezers; experiment class: force_generation_motor, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-007609-r0 SMASH-BIO | force_spectroscopy | step_size: 8 nm ± 6 | in vitro Modelling and simulation of motility in actomyosin systems. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007610 SMASH-BIO | force_spectroscopy | study_record | in vitro Molecular mechanics of two smooth muscle heavy meromyosin constructs that differ by an insert in the motor domain. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007613 SMASH-BIO | force_spectroscopy | study_record | in vitro Orientation dependence of displacements by a single one-headed myosin relative to the actin filament. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007620 SMASH-BIO | force_spectroscopy | study_record | in vitro The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007630 SMASH-BIO | force_spectroscopy | study_record | in vitro Actin filament mechanics in the laser trap. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007635 SMASH-BIO | force_spectroscopy | study_record | in vitro Force effects on biochemical kinetics. · Myosin; optical tweezers; experiment class: chromatin_mechanics, force_generation_motor | unmapped |
| EV-SMASH-SMFS-007636 SMASH-BIO | force_spectroscopy | study_record | in vitro Imaging and nano-manipulation of single biomolecules. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007640 SMASH-BIO | force_spectroscopy | study_record | in vitro Movements of truncated kinesin fragments with a short or an artificial flexible neck. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007643 SMASH-BIO | force_spectroscopy | study_record | in vitro Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007650-r0 SMASH-BIO | force_spectroscopy | rupture_force: 1.5 pN | in vitro Direct inhibition of the actomyosin motility by local anesthetics in vitro. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007656 SMASH-BIO | force_spectroscopy | study_record | in vitro Multiple- and single-molecule analysis of the actomyosin motor by nanometer-piconewton manipulation with a microneedle: unitary steps and forces. · Myosin; microneedle; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007660 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule mechanics. · Myosin; force spectroscopy unspecified; experiment class: force_generation_motor, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-007666 SMASH-BIO | force_spectroscopy | study_record | in vitro Characterization of single actin-myosin interactions. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007667 SMASH-BIO | force_spectroscopy | study_record | in vitro Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007668 SMASH-BIO | force_spectroscopy | study_record | in vitro In vitro motility of immunoadsorbed brain myosin-V using a Limulus acrosomal process and optical tweezer-based assay. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007669-r0 SMASH-BIO | force_spectroscopy | step_size: 11 nm | in vitro Mechanical measurements of single actomyosin motor force. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007670 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical properties of neuronal growth cone membranes studied by tether formation with laser optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007672 SMASH-BIO | force_spectroscopy | study_record | in vitro Micromanipulation of statoliths in gravity-sensing Chara rhizoids by optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor, membrane_mechanics, rheology_cell | unmapped |
| EV-SMASH-SMFS-007673 SMASH-BIO | force_spectroscopy | study_record | in vitro Movement and force produced by a single myosin head. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007676 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule mechanics of heavy meromyosin and S1 interacting with rabbit or Drosophila actins using optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell | unmapped |
| EV-SMASH-SMFS-007679 SMASH-BIO | force_spectroscopy | study_record | in vitro Transcription against an applied force. · Myosin; optical tweezers; experiment class: force_generation_motor, rheology_cell, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-007680-r0 SMASH-BIO | force_spectroscopy | unbinding_force: 9.2 pN ± 4.4 | in vitro Unbinding force of a single motor molecule of muscle measured using optical tweezers. · Myosin; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007682-r0 SMASH-BIO | force_spectroscopy | step_size: 71 nm ± 22 | in vitro Movement of single myosin filaments and myosin step size on an actin filament suspended in solution by a laser trap. · Myosin; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization | unmapped |
| EV-SMASH-SMFS-007684-r0 SMASH-BIO | force_spectroscopy | step_size: 11 nm | in vitro Single myosin molecule mechanics: piconewton forces and nanometre steps. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007685 SMASH-BIO | force_spectroscopy | study_record | in vitro Stepwise motion of an actin filament over a small number of heavy meromyosin molecules is revealed in an in vitro motility assay. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007690 SMASH-BIO | force_spectroscopy | study_record | in vitro Orientation of actin monomers in moving actin filaments. · Myosin; optical tweezers; experiment class: force_generation_motor | unmapped |
Conflicts
No conflicts found among comparable evidence.
365 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.