L-selectin
UniProt P14151 · gene SELL · Homo sapiens · 372 residues
14evidence items
0mapped to a state
0states
5techniques
4sources
0conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | nmr_structure | nmr_shifts | force_spectroscopy | af_prediction | Total |
|---|---|---|---|---|---|---|---|
| No states defined yet. | |||||||
Unmapped evidence: 14 of 14 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 1 | 0 |
| RCSB PDB | 3 | 0 |
| SMASH-BIO | 9 | 0 |
Structure
No state models are exported for this protein yet. Observed states export the representative PDB entry; inferred states need fitted models, not yet built.
States and transitions
No states defined.
| State | Basis | Parent | Description |
|---|
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-2LGF-2 RCSB PDB | nmr_structure | structure | in vitro · 29.85 °C · pH 6.8 · ligands CA Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of L-selectin · L-selectin (chains B) | unmapped |
| EV-PDB-3CFW-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -173.15 °C · pH 8.5 · ligands CA, NAG, branched: alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose L-selectin lectin and EGF domains · L-selectin (chains A) | unmapped |
| EV-PDB-5VC1-1 RCSB PDB | xray | resolution: 1.94 Å | in vitro · -173.15 °C · pH 7.5 · ligands CA, GOL, PEG, PG4, branched: beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Crystal structure of L-selectin lectin/EGF domains · L-selectin (chains A) | unmapped |
| EV-BMRB-17807 BMRB | nmr_shifts | chemical_shift | in vitro · 29.85 °C · pH 6.8 Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of L-selectin · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-AFDB-AF-P14151-F1 AlphaFold DB | af_prediction | plddt: 85.31 pLDDT | in silico AlphaFold DB prediction AF-P14151-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-372 | unmapped |
| EV-SMASH-SMFS-001948-r0 SMASH-BIO | force_spectroscopy | adhesion_force: 148 pN | in vitro · pH 7 Highly glycosylated MUC1 mediates high affinity L-selectin binding at the human endometrial surface. · L-selectin; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003682 SMASH-BIO | force_spectroscopy | study_record | in vitro Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow. · L-selectin; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-004184 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.8 Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow. · L-selectin; afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005961 SMASH-BIO | force_spectroscopy | study_record | in vitro Triphasic force dependence of E-selectin/ligand dissociation governs cell rolling under flow. · L-selectin; biomembrane force probe; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006320-r0 SMASH-BIO | force_spectroscopy | equilibrium_force: 44 pN | in vitro Enhancement of L-selectin, but not P-selectin, bond formation frequency by convective flow. · L-selectin; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006445 SMASH-BIO | force_spectroscopy | study_record | in vitro Selectin catch-slip kinetics encode shear threshold adhesive behavior of rolling leukocytes. · L-selectin; biomembrane force probe; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006516 SMASH-BIO | force_spectroscopy | study_record | in vitro Adhesive dynamics simulations of the shear threshold effect for leukocytes. · L-selectin; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007126 SMASH-BIO | force_spectroscopy | study_record | in vitro Distinct kinetic and mechanical properties govern selectin-leukocyte interactions. · L-selectin; afm smfs; experiment class: receptor_ligand_adhesion, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-007214 SMASH-BIO | force_spectroscopy | study_record | in vitro The molecular mechanics of P- and L-selectin lectin domains binding to PSGL-1. · L-selectin; optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
Conflicts
No conflicts found among comparable evidence.
14 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.