Microtubule-associated protein tau
UniProt P10636 · gene MAPT · Homo sapiens · 758 residues
374evidence items
299mapped to a state
3states
11techniques
6sources
1conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | microed | nmr_structure | nmr_shifts | saxs_sans | cd | ftir_raman | force_spectroscopy | integrative | af_prediction | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| disordered monomer tau-disordered | inferred | · | · | · | · | · | rep 3 | rep 1 | rep 1 | · | · | · | 5 |
| amyloid filament tau-filament | observed | proc 1 | proc 2 | · | · | · | · | · | · | · | · | · | 3 |
| microtubule-bound tau-microtubule | observed | proc 36 | proc 232 | proc 3 | proc 8 | proc 1 | proc 8 | · | · | rep 3 | · | · | 291 |
Unmapped evidence: 75 of 374 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 10 | 1 |
| DisProt | 5 | 5 |
| RCSB PDB | 315 | 282 |
| SASBDB | 8 | 8 |
| SMASH-BIO | 35 | 3 |
Curated rules applied
tau-disprot-disorder: 5 itemstau-filament-title: 2 itemstau-microtubule-title: 290 items
Structure
Choose a state. Each model is badged observed or inferred; assumptions are one click away.
States and transitions
| State | Basis | Parent | Description |
|---|---|---|---|
| disordered monomer tau-disordered | inferred | — | Intrinsically disordered monomer in solution. No observed structure.Assumptions (2)
|
| amyloid filament tau-filament | observed | — | Cross-beta filament core, as in 5O3L (paired helical filament from Alzheimer's disease brain). Filament folds are not separated. |
| microtubule-bound tau-microtubule | observed | — | Repeat region bound along the microtubule surface, as in 6CVN. |
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-10IK-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro S305I Frontotemporal Lobar Degeneration (FTLD) type II tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10NQ-1 RCSB PDB | cryoem | resolution: 3.61 Å | in vitro u-VT Ic tau filament from VT Case 1 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-1I8H-1 RCSB PDB | nmr_structure | structure | in vitro · 11.85 °C · pH 6.4 SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH HUMAN TAU PHOSPHOTHREONINE PEPTIDE · MICROTUBULE-ASSOCIATED PROTEIN TAU (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-28LO-1 RCSB PDB | cryoem | resolution: 2.1 Å | in vitro Tau filament with G272V mutation · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-2ON9-1 RCSB PDB | xray | resolution: 1.51 Å | in vitro · -173.15 °C · pH 7.5 Structure of an amyloid forming peptide VQIVYK from the repeat region of Tau · VQIVYK peptide corresponding to residues 306-311 in the tau protein (chains A,B) | amyloid filament · rule:tau-filament-title · high Structure titled as a filament or fibril. |
| EV-PDB-37VX-1 RCSB PDB | cryoem | resolution: 2.78 Å | in vitro CTE Type I structure · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-37VY-1 RCSB PDB | cryoem | resolution: 2.96 Å | in vitro CTE Type I-like structure · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-4TQE-3 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · ligands NA, PGE, SO4 Structure of tau peptide in complex with Tau5 antibody Fab fragment · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5DMG-3 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · pH 4.5 X-RAY STRUCTURE OF THE FAB FRAGMENT OF THE ANTI TAU ANTIBODY RB86 IN COMPLEX WITH THE PHOSPHORYLATED TAU PEPTIDE (416-430) · Microtubule-associated protein (chains P,X,Z) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5MP1-3 RCSB PDB | xray | resolution: 3.1 Å | in vitro · -173.15 °C · pH 7.5 Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 7.5 · Microtubule-associated protein tau (chains A,B,E,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5O3L-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Paired helical filament in Alzheimer's disease brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | amyloid filament · curator:draft (unreviewed) · high Paired helical filament, cryo-EM. |
| EV-PDB-5O3T-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Straight filament in Alzheimer's disease brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5ZIA-3 RCSB PDB | xray | resolution: 2.603 Å | in vitro · -173.15 °C · pH 8.5 Crystal structure of human anti-tau antibody CBTAU-24.1 in complex with its phosphorylated tau peptide · phosphorylated tau peptide (chains C,F,J,N,Q,R) | unmapped |
| EV-PDB-5ZV3-1 RCSB PDB | xray | resolution: 2.093 Å | in vitro · -173.15 °C · pH 8.5 Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide · Peptide from Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5V5C-1 RCSB PDB | microed | resolution: 1.25 Å | in vitro · -173.15 °C · pH 7 VQIINK, Structure of the amyloid-spine from microtubule associated protein tau Repeat 2 · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5V5B-1 RCSB PDB | microed | resolution: 1.5 Å | in vitro · -173.15 °C · pH 4.2 KVQIINKKLD, Structure of the amyloid spine from microtubule associated protein tau Repeat 2 · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5O3O-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro Pronase-treated paired helical filament in Alzheimer's disease brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5NVB-1 RCSB PDB | nmr_structure | structure | in vitro · 4.85 °C · pH 6.8 Structure of Tau(254-268) bound to F-actin · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5N5B-1 RCSB PDB | nmr_structure | structure | in vitro · 4.85 °C · pH 6.8 Structure of Tau(292-319) bound to F-actin · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5N5A-1 RCSB PDB | nmr_structure | structure | in vitro · 4.85 °C · pH 6.8 Structure of Tau(254-290) bound to F-actin · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5MP5-3 RCSB PDB | xray | resolution: 2.31 Å | in vitro · -173.15 °C · pH 6.5 Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 6.5 · Microtubule-associated protein tau (chains I,J,K) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5MP3-3 RCSB PDB | xray | resolution: 2.75 Å | in vitro · -173.15 °C · pH 6.5 Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5 · Microtubule-associated protein (chains C,D) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5MO3-1 RCSB PDB | xray | resolution: 1.69 Å | in vitro · -173.15 °C · pH 8.5 · ligands PGE, branched: alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 8.5 · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-5K7N-1 RCSB PDB | microed | resolution: 1.1 Å | in vitro MicroED structure of tau VQIVYK peptide at 1.1 A resolution · VQIVYK (chains Z) | unmapped |
| EV-PDB-5HF3-2 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173.15 °C · pH 7.1 Crystal structure of C-terminal modified Tau peptide-hybrid 201D with 14-3-3sigma · modified Tau peptide (chains B) | unmapped |
| EV-PDB-5E2W-3 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 7.5 Anti-TAU AT8 FAB with triply phosphorylated TAU peptide · TAU-PHOSPHOPEPTIDE (chains P) | unmapped |
| EV-PDB-5E2V-3 RCSB PDB | xray | resolution: 1.64 Å | in vitro · -173.15 °C · pH 6.5 · ligands GOL Anti-TAU AT8 FAB with doubly phosphorylated TAU peptide · TAU PHOSPHOPEPTIDE (chains P) | unmapped |
| EV-PDB-5BTV-2 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · ligands CA, CL, MG Crystal structure of human 14-3-3 sigma in complex with a Tau-protein peptide surrounding pS324 · Microtubule-associated protein tau - peptide pS324 (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-4Y5I-2 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 7.1 · ligands CL Crystal structure of C-terminal modified Tau peptide-hybrid 126B with 14-3-3sigma · Microtubule-associated protein tau (chains F,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-4Y32-2 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 7.1 · ligands 49F Crystal structure of C-terminal modified Tau peptide-hybrid 109B with 14-3-3sigma · ARG-THR-PRO-SEP-LEU-PRO-CNC(C(C)O)C(=O)N1CCCC1CCOC (chains C,D) | unmapped |
| EV-PDB-4NP8-1 RCSB PDB | xray | resolution: 1.51 Å | in vitro · -173.15 °C · pH 7.5 Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph) · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-4GLR-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -73.15 °C · pH 7 · ligands PO4 Structure of the anti-ptau Fab (pT231/pS235_1) in complex with phosphoepitope pT231/pS235 · phospho-peptide (chains A,B) | unmapped |
| EV-PDB-4FL5-2 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 7.5 · ligands CA, CL, GOL, MG Crystal structure of human 14-3-3 sigma in complex with a Tau-protein peptide surrounding pS214 · Microtubule-associated protein tau (chains P,Q) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-4E0O-1 RCSB PDB | xray | resolution: 1.82 Å | in vitro · -173.15 °C · pH 6.2 · ligands MPD, PO4 SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form III) · Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN) (chains A,B,C,D) | unmapped |
| EV-PDB-4E0N-1 RCSB PDB | xray | resolution: 1.65 Å | in vitro · -173.15 °C · pH 6.2 · ligands MPD, PO4 SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form II) · Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN) (chains A,B,C,D) | unmapped |
| EV-PDB-4E0M-1 RCSB PDB | xray | resolution: 1.75 Å | in vitro · -173.15 °C · pH 6.2 · ligands MPD, PO4 SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form I) · Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN) (chains A,B,C,D) | unmapped |
| EV-PDB-3OVL-1 RCSB PDB | xray | resolution: 1.81 Å | in vitro · -173.15 °C · ligands ACY, ORA, ZN Structure of an amyloid forming peptide VQIVYK from the TAU protein in complex with orange G · Microtubule-associated protein (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-2MZ7-1 RCSB PDB | nmr_structure | structure | in vitro · 4.85 °C · pH 6.8 Structure of Tau(267-312) bound to Microtubules · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-28LQ-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Tau filament with S320F mutation · Isoform Tau-C of Microtubule-associated protein tau (chains A,B,C,D) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-28LP-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro Tau filament with delG389_I392 mutation · Isoform Tau-C of Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-28LJ-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Tau filament with D252V mutation · Isoform Tau-C of Microtubule-associated protein tau (chains A,B,C,D) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-22JY-1 RCSB PDB | cryoem | resolution: 2.2 Å | in vitro P301L/S320F human tau filaments from mouse brain · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10NT-1 RCSB PDB | cryoem | resolution: 3.05 Å | in vitro u-VT IV tau filament from VT Case 1 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10NR-1 RCSB PDB | cryoem | resolution: 3.37 Å | in vitro u-VT II tau filament from VT Case 1 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10NP-1 RCSB PDB | cryoem | resolution: 3.51 Å | in vitro u-VT Ib tau filament from VT Case 1 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10NO-1 RCSB PDB | cryoem | resolution: 2.96 Å | in vitro u-VT Ia tau filament from VT Case 2 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10MS-1 RCSB PDB | cryoem | resolution: 3.24 Å | in vitro VT IV tau filament from VT Case 2 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10MR-1 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro VT II tau filament from VT Case 1 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10LN-1 RCSB PDB | cryoem | resolution: 2.92 Å | in vitro VT Ia tau filament from VT Case 1 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-10IJ-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro S305I Frontotemporal Lobar Degeneration (FTLD) type I tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6BB4-3 RCSB PDB | xray | resolution: 2.099 Å | in vitro · -173.15 °C · ligands PO4 Fab/epitope complex of mouse monoclonal antibody C5.2 targeting a phospho-tau epitope. · Microtubule-associated protein tau (chains P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6CVN-3 RCSB PDB | cryoem | resolution: 3.9 Å | in vitro · ligands GDP, GTP, MG Model of synthetic tau (R2x4) bound to the microtubule · Microtubule-associated protein tau (chains D) | microtubule-bound · curator:draft (unreviewed) · high Synthetic tau (R2x4) bound to the microtubule, cryo-EM. |
| EV-PDB-6DC8-3 RCSB PDB | xray | resolution: 1.799 Å | in vitro · -173.15 °C · ligands GOL, PO4 Fab/epitope complex of mouse monoclonal antibody 8B2 targeting a non-phosphorylated tau epitope. · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6DC9-3 RCSB PDB | xray | resolution: 2.999 Å | in vitro · -173.15 °C · ligands GOL, PO4 Fab/epitope complex of human chimeric monoclonal antibody h4E6 targeting a phosphorylated tau epitope. · Microtubule-associated protein tau (chains P,Q) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6DCA-3 RCSB PDB | xray | resolution: 2.599 Å | in vitro · -173.15 °C · ligands PO4 Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope. · Microtubule-associated protein tau (chains P,Q,R,S) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6FAW-3 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 7.5 · ligands CL, D3K, MG, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2c-I with 14-3-3sigma · THR-PRO-SEP-LEU-PRO-GLY (chains D) | unmapped |
| EV-PDB-6FAW-2 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 7.5 · ligands CL, D3K, MG, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2c-I with 14-3-3sigma · ACE-ARG-THR-PRO-SEP-LEU-PRO-GLY (chains B) | unmapped |
| EV-PDB-6FBW-2 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · pH 7.3 · ligands CL, D4K, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2f-II with 14-3-3sigma · ARG-THR-PRO-SEP-LEU-PRO-GLY (chains B,D) | unmapped |
| EV-PDB-6FI5-2 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · ligands 60H, CL, MG, NA Crystal structure of C-terminal modified Tau peptide-hybrid 3.2d with 14-3-3sigma · THR-PRO-SEP-LEU-PRO-DAL (chains B) | unmapped |
| EV-PDB-6GK7-3 RCSB PDB | xray | resolution: 2.95 Å | in vitro · -173.15 °C · ligands CL Crystal structure of anti-tau antibody dmCBTAU-27.1, double mutant (S31Y, T100I) of CBTAU-27.1, in complex with Tau peptide A8119B (residues 299-318) · HUMAN TAU PEPTIDE A8119 RESIDUES 299-318 (chains A) | unmapped |
| EV-PDB-6HRE-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Paired helical filament from sporadic Alzheimer's disease brain · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6HRF-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Straight filament from sporadic Alzheimer's disease brain · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6N4P-1 RCSB PDB | xray | resolution: 1.851 Å | in vitro · -173.15 °C RQEFEV, crystal structure of the N-terminal segment RQEFEV from protein tau · Microtubule-associated protein tau (chains A,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6NK4-1 RCSB PDB | microed | resolution: 1.994 Å | in vitro · -185.15 °C KVQIINKKL, crystal structure of a tau protein fragment · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6NWP-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro Chronic traumatic encephalopathy Type I Tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6ODG-1 RCSB PDB | xray | resolution: 1 Å | in vitro · -180.15 °C SVQIVY, Crystal Structure of a tau protein fragment · Microtubule-associated protein tau (chains A,B) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6QJH-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Cryo-EM structure of heparin-induced 2N4R tau snake filaments · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6QJQ-1 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro Cryo-EM structure of heparin-induced 2N3R tau filaments · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6TJO-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6VH7-1 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro Doublet Tau Fibril from Corticobasal Degeneration Human Brain Tissue · Microtubule-associated protein tau (chains A,B,C,E,F,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6XLI-3 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · ligands GOL CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE · Tau Phosphopeptide (Ac-SR(pT)PSLP(pT)PPTRE-OH) (chains E,F,P) | unmapped |
| EV-PDB-7EYC-3 RCSB PDB | xray | resolution: 2.49 Å | in vitro · -173.15 °C Crystal structure of Tau and acetylated tau peptide antigen · ACETYLATED TAU PEPTIDE (chains P,Q) | unmapped |
| EV-PDB-7KQK-3 RCSB PDB | xray | resolution: 2.6 Å | in vitro · -193.15 °C anti-pTau C21-ABS Fab in complex with pTau peptide · pTau peptide (chains C,P) | unmapped |
| EV-PDB-7MKF-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Paired helical tau filament extracted from PrP-CAA Patient brain tissue | tau filament | PHF Tau · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7MKG-1 RCSB PDB | cryoem | resolution: 3.07 Å | in vitro Straight tau filament extracted from PrP-CAA Patient brain tissue | tau filament | SF Tau · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7MKH-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Paired helical tau filament extracted from GSS Patient brain tissue | tau filament from Gerstmann Straussler Scheinker disease | PHF Tau · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7NRQ-1 RCSB PDB | cryoem | resolution: 2.76 Å | in vitro Paired helical filament from primary age-related tauopathy brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7NRS-1 RCSB PDB | cryoem | resolution: 2.68 Å | in vitro Conformation 1 of straight filament from primary age-related tauopathy brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7NRT-1 RCSB PDB | cryoem | resolution: 2.68 Å | in vitro Conformation 2 of straight filament from primary age-related tauopathy brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7NRV-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Paired helical filament from Alzheimer's disease with PET ligand APN-1607 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7NRX-1 RCSB PDB | cryoem | resolution: 3.55 Å | in vitro Straight filament from Alzheimer's disease with PET ligand APN-1607 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P65-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Progressive supranuclear palsy tau filament · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P66-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Globular glial tauopathy type 1 tau filament · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P67-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Globular glial tauopathy type 2 tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6VI3-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands GLY Straight Filament from Alzheimer's Disease Human Brain Tissue · Microtubule-associated protein tau (chains E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6VHL-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands GLY Paired Helical Filament from Alzheimer's Disease Human Brain Tissue · Microtubule-associated protein tau (chains E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6VHA-1 RCSB PDB | cryoem | resolution: 4.3 Å | in vitro Singlet Tau Fibril from Corticobasal Degeneration Human Brain Tissue · Microtubule-associated protein tau (chains E,F,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6TJX-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6QJP-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro Cryo-EM structure of heparin-induced 2N4R tau jagged filaments · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6QJM-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Cryo-EM structure of heparin-induced 2N4R tau twister filaments · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6PXR-3 RCSB PDB | xray | resolution: 1.556 Å | in vitro · -173.15 °C Anti-TAU BIIB092 FAB with TAU peptide · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6NWQ-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Chronic traumatic encephalopathy Type II Tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6LRA-3 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C The complex structure of PHF core domain peptide of tau and antibody's Fab domain. · VQIINK (chains C) | unmapped |
| EV-PDB-6H06-3 RCSB PDB | xray | resolution: 2.63 Å | in vitro · -173.15 °C · pH 7 · ligands GOL FAB CBTAU-22.1 IN COMPLEX WITH TAU PEPTIDE V1088-5 · Microtubule-associated protein tau (chains G,I,J,K) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6GX5-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Narrow Pick Filament from Pick's disease brain · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-6GK8-3 RCSB PDB | xray | resolution: 2.85 Å | in vitro · -173.15 °C · pH 6.75 · ligands CL Crystal structure of anti-tau antibody dmCBTAU-28.1, double mutant (S32R, E35K) of CBTAU-28.1, in complex with Tau peptide A7731 (residues 52-71) · TAU PEPTIDE A7731 (RESIDUES 52-71) (chains I) | unmapped |
| EV-PDB-6FI4-2 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 7.1 · ligands 60H, CA, CL, NA Crystal structure of C-terminal modified Tau peptide-hybrid 3.2e with 14-3-3sigma · PRO-SEP-LEU-PRO-DVA (chains B) | unmapped |
| EV-PDB-6FBY-3 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 7.1 · ligands CL, D4H, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2b with 14-3-3sigma · THR-PRO-SEP-LEU-PRO-GLY (chains D) | unmapped |
| EV-PDB-6FBY-2 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 7.1 · ligands CL, D4H, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2b with 14-3-3sigma · ACE-ARG-THR-PRO-SEP-LEU-PRO-GLY (chains B) | unmapped |
| EV-PDB-6FAV-3 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 7.1 · ligands CL, D3Q, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2f-I with 14-3-3sigma · THR-PRO-SEP-LEU-PRO-GLY (chains D) | unmapped |
| EV-PDB-6FAV-2 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 7.1 · ligands CL, D3Q, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2f-I with 14-3-3sigma · ACE-ARG-THR-PRO-SEP-LEU-PRO-GLY (chains B) | unmapped |
| EV-PDB-6FAU-3 RCSB PDB | xray | resolution: 1.25 Å | in vitro · -173.15 °C · ligands CL, D3W, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2e-I with 14-3-3sigma · THR-PRO-SEP-LEU-PRO-GLY (chains D) | unmapped |
| EV-PDB-6FAU-2 RCSB PDB | xray | resolution: 1.25 Å | in vitro · -173.15 °C · ligands CL, D3W, NA Crystal structure of C-terminal modified Tau peptide-hybrid 4.2e-I with 14-3-3sigma · ACE-ARG-THR-PRO-SEP-LEU-PRO-GLY (chains B) | unmapped |
| EV-PDB-6CVJ-3 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands GDP, GTP, MG Model of synthetic tau (four tandem repeats of first repeat sequence) bound to the microtubule · Microtubule-associated protein tau (chains D) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P68-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Globular glial tauopathy type 3 tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P6A-1 RCSB PDB | cryoem | resolution: 1.9 Å | in vitro Limbic-predominant neuronal inclusion body 4R tauopathy type 1a tau filament · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P6C-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro Limbic-predominant neuronal inclusion body 4R tauopathy type 2 tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P6D-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Argyrophilic grain disease type 1 tau filament · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7PQC-3 RCSB PDB | cryoem | resolution: 4.1 Å | in vitro · ligands GDP, GTP, MG tau-microtubule structural ensemble based on CryoEM data · Isoform Tau-F of Microtubule-associated protein tau (chains O) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7PQP-3 RCSB PDB | cryoem | resolution: 4.1 Å | in vitro · ligands GDP, GTP, MG tau-microtubule structural ensemble based on CryoEM data · Isoform Tau-F of Microtubule-associated protein tau (chains O) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QJV-1 RCSB PDB | cryoem | resolution: 3.29 Å | in vitro In vitro assembled tau filaments into Quadruple Helical Filaments type 1 (2c) · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QJW-1 RCSB PDB | cryoem | resolution: 2.81 Å | in vitro In vitro assembled tau filaments with structures like chronic traumatic encephalopathy type II (8a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QK2-1 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro In vitro assembled 300-391 tau filaments in PBS (36a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKI-1 RCSB PDB | cryoem | resolution: 3.13 Å | in vitro In vitro assembled 297-408 S396D S400D T403D S404D tau filaments (42a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKJ-1 RCSB PDB | cryoem | resolution: 3.26 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with MgCl2 and NaCl (14b) · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKU-1 RCSB PDB | cryoem | resolution: 2.57 Å | in vitro in vitro assembled 266/297 - 391 tau filaments with MgCl2 and NaCl (14a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKV-1 RCSB PDB | cryoem | resolution: 3.23 Å | in vitro In vitro assembled tau filaments with MgSO4 and NaCl (15a) · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKY-1 RCSB PDB | cryoem | resolution: 1.86 Å | in vitro In vitro assembled 0N4R tau filaments with phosphoserine (47a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKZ-1 RCSB PDB | cryoem | resolution: 2.65 Å | in vitro In vitro assembled 305-379 tau filaments (27a) · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QL0-1 RCSB PDB | cryoem | resolution: 3.13 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15c) · Microtubule-associated protein tau (chains A,B,C,D,E,c) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QL1-1 RCSB PDB | cryoem | resolution: 3.34 Å | in vitro In vitro assembled 266-391 tau filaments in PBS (23a) · Microtubule-associated protein tau (chains A,C,D) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7R4T-1 RCSB PDB | cryoem | resolution: 2.75 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with NaHCO3 and NaCl (16a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7U0Z-1 RCSB PDB | cryoem | resolution: 4.2 Å | in vitro High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1 · Isoform Tau-E of Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7UPF-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Tau Paired Helical Filament from Alzheimer's Disease incubated 1 hr. with EGCG · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7UPG-1 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro · ligands KDH Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7YMN-1 RCSB PDB | cryoem | resolution: 3.46 Å | in vitro Cryo-EM structure of in vitro PHF fibril · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7YPG-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro Cryo-EM structure of amyloid fibril formed by tau (297-391) · Isoform Tau-E of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8AZU-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Paired helical tau filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | PHF Tau · Microtubule-associated protein tau (chains C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8BGS-1 RCSB PDB | cryoem | resolution: 3.16 Å | in vitro Tau Paired Helical Filament from Extracellular Vesicles from Alzheimer's disease brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,r) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8BYN-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro · ligands S9C Chronic traumatic encephalopathy tau filaments with PET ligand flortaucipir · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8BGV-1 RCSB PDB | cryoem | resolution: 3.27 Å | in vitro Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain · Microtubule-associated protein tau (chains A,B,C,D,E,F,n) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7UPE-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7SP1-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro RNA-induced tau amyloid fibril · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7R5H-1 RCSB PDB | cryoem | resolution: 2.59 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with KCl (10b) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QL4-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro in vitro assembled tau filaments with structures like Paired Helical Filaments from Alzheimer's Disease · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QL3-1 RCSB PDB | cryoem | resolution: 3.32 Å | in vitro in vitro assembled 266/297 - 391 tau filaments with NaCl (8b) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QL2-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro In vitro assembled 244-391 tau filaments with Na2P2O7 (20a) · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKX-1 RCSB PDB | cryoem | resolution: 3.16 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15b) · Microtubule-associated protein tau (chains A,B,C,D,E,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKW-1 RCSB PDB | cryoem | resolution: 2.32 Å | in vitro In vitro assembled 266-391 S356D tau filaments with KCl (44a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKM-1 RCSB PDB | cryoem | resolution: 2.66 Å | in vitro In vitro assembled 266-391 S356D tau filaments with NaCl (45a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKL-1 RCSB PDB | cryoem | resolution: 2.07 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with ZnCl2 (11a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKK-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro In vitro assembled 258-391 tau filaments with phosphoglycerate, 700 rpm (39a) · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKH-1 RCSB PDB | cryoem | resolution: 3.17 Å | in vitro In vitro assembled 258-391 tau filaments with sodium azide, (41a) · Microtubule-associated protein tau (chains A,B,C,D,E,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKG-1 RCSB PDB | cryoem | resolution: 3.36 Å | in vitro In vitro assembled 258-391 tau filaments with phosphoglycerate, 700 rpm (39a) · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QKF-1 RCSB PDB | cryoem | resolution: 2.83 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with CuCl2 (12a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QK6-1 RCSB PDB | cryoem | resolution: 2.27 Å | in vitro In vitro assembled 258-391 tau filaments with heparan sulfate, 700 rpm (40a) · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QK5-1 RCSB PDB | cryoem | resolution: 1.92 Å | in vitro · ligands CL, K In vitro assembled 266/297 - 391 tau filaments with KCl (10a) · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,K) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QK3-1 RCSB PDB | cryoem | resolution: 2.44 Å | in vitro In vitro assembled 258-391 tau filaments, 700 rpm (38a) · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QK1-1 RCSB PDB | cryoem | resolution: 3.03 Å | in vitro In vitro assembled 297-394 tau filaments in PBS (35d) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QJZ-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with LiCl (9b) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QJY-1 RCSB PDB | cryoem | resolution: 3.14 Å | in vitro In vitro assembled 266/297 - 391 tau filaments with LiCl (9a) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7QJX-1 RCSB PDB | cryoem | resolution: 2.99 Å | in vitro In vitro assembled 297-394 tau filaments, 700 rpm (34b) · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P6E-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Argyrophilic grain disease type 2 tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F,I,J,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-7P6B-1 RCSB PDB | cryoem | resolution: 2.2 Å | in vitro Limbic-predominant neuronal inclusion body 4R tauopathy type 1b tau filament · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OTG-1 RCSB PDB | cryoem | resolution: 2.1 Å | in vitro CTE typeI tau filament from Kii ALS/PDC · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OTJ-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro PHF tau filament from Kii ALS/PDC · Microtubule-associated protein tau (chains A,B,C,D,E,F,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8W-1 RCSB PDB | cryoem | resolution: 2.85 Å | in vitro Tau - CTE-MIA4 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8V-1 RCSB PDB | cryoem | resolution: 3.8 Å | in vitro Tau - CTE-MIA3 · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8U-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Tau - CTE-MIA1 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8S-1 RCSB PDB | cryoem | resolution: 2.68 Å | in vitro Tau - AD-THF · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8R-1 RCSB PDB | cryoem | resolution: 2.1 Å | in vitro Tau - AD-PHF · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8M-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro Tau - AD-PHF long crossover · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8L-1 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro Tau - AD-LIA7 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8F-1 RCSB PDB | cryoem | resolution: 2.93 Å | in vitro Tau - AD-LIA5 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8E-1 RCSB PDB | cryoem | resolution: 3.81 Å | in vitro Tau - AD-LIA4 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8D-1 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro Tau - AD-LIA6 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8C-1 RCSB PDB | cryoem | resolution: 1.92 Å | in vitro Tau - AD-MIA10 (intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q88-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro Tau - AD-LIA2 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q7T-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Tau - AD-MIA11 · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q7P-1 RCSB PDB | cryoem | resolution: 3.28 Å | in vitro Tau - AD-MIA8 (intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q7M-1 RCSB PDB | cryoem | resolution: 3.26 Å | in vitro Tau - AD-MIA7 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q7L-1 RCSB PDB | cryoem | resolution: 2.82 Å | in vitro Tau - AD-MIA6 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q7F-1 RCSB PDB | cryoem | resolution: 3.72 Å | in vitro Tau - AD-MIA5 · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q2L-1 RCSB PDB | cryoem | resolution: 2.2 Å | in vitro Tau - AD-MIA4 · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q2K-1 RCSB PDB | cryoem | resolution: 2.88 Å | in vitro Tau - AD-MIA3 · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q2J-1 RCSB PDB | cryoem | resolution: 2.23 Å | in vitro Tau - AD-MIA2 · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q27-1 RCSB PDB | cryoem | resolution: 2.02 Å | in vitro Tau: AD-MIA1 · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8PPO-1 RCSB PDB | cryoem | resolution: 2 Å | in vitro First Intermediate Amyloid (FIA) - Tau · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8PII-2 RCSB PDB | xray | resolution: 2.35 Å | in vitro · -173.15 °C · pH 7.5 VHH Z70 mutant 3 in interaction with PHF6 Tau peptide · Microtubule-associated protein tau (chains B) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8P34-1 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT · Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OTI-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro CTE typeIII tau filament · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OTH-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro TypeII tau filament from Kii ALS/PDC · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OTC-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro CTE typeII tau filament from Guam ALS/PDC · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OT9-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro CTE typeIII tau filament from Guam ALS/PDC · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OT6-1 RCSB PDB | cryoem | resolution: 2 Å | in vitro CTE typeI tau filament from Guam ALS/PDC · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8ORG-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts (Type II) · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8ORF-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8ORE-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro Cryo-EM structure of SH-SY5Y seeded with filaments from Alzheimer's Disease · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OPI-2 RCSB PDB | xray | resolution: 1.83 Å | in vitro · -173.15 °C · pH 7.4 VHH Z70 mutant 1 in interaction with PHF6 Tau peptide · PHF6 Tau peptide (chains B) | unmapped |
| EV-PDB-8OP0-2 RCSB PDB | xray | resolution: 1.54 Å | in vitro · -173.15 °C · pH 5.6 VHH Z70 mutant 20 in interaction with PHF6 Tau peptide · Tau PHF6 peptide (chains B) | unmapped |
| EV-PDB-8OI0-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Structure of the Fmoc-Tau-PAM4 Type 4 amyloid fibril · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OHP-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Structure of the Fmoc-Tau-PAM4 Type 3 amyloid fibril · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OHI-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Structure of the Fmoc-Tau-PAM4 Type 2 amyloid fibril · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8OH2-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro Structure of the Tau-PAM4 Type 1 amyloid fibril · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,a,b,c,d,e,f,g,h,i,j) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8KDX-2 RCSB PDB | xray | resolution: 1.01 Å | in vitro · -173.15 °C · pH 8.5 Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current · Microtubule-associated protein tau (chains B) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8GCK-2 RCSB PDB | xray | resolution: 1.36824 Å | in vitro · -173.15 °C Crystal structure of the human CHIP-TPR domain in complex with a 6mer acetylated tau peptide · ACE-SER-ILE-ASP-MET-VAL-ASP (chains C,E) | unmapped |
| EV-PDB-8G58-1 RCSB PDB | nmr_structure | structure | in vitro · 13.85 °C · pH 5 Tau (297-391) in vitro untwisted fibril · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8G55-1 RCSB PDB | nmr_structure | structure | in vitro · 11.85 °C · pH 7.4 Temperature-dependent structures of tau aggregates · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8G54-1 RCSB PDB | nmr_structure | structure | in vitro · 21.85 °C · pH 7.4 Temperature-dependent structures of tau aggregates · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8FYU-2 RCSB PDB | xray | resolution: 1.84839 Å | in vitro · -173.15 °C Crystal structure of the human CHIP-TPR domain in complex with a 10mer acetylated tau peptide · ACE-SER-SER-THR-GLY-SER-ILE-ASP-MET-VAL-ASP (chains C,E) | unmapped |
| EV-PDB-8FUG-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro · ligands Y9H Alzheimer's disease paired-helical filament in complex with PET tracer GTP-1 · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8FNZ-1 RCSB PDB | cryoem | resolution: 3.88 Å | in vitro Acetylated tau repeat 1 and 2 fragment (AcR1R2) · Microtubule-associated protein tau, acetylated repeat 1 and 2 fragment (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,a,b,c,d,e,f,g,h,i,j,k,l,m,n,o,p,q,r,s,t,u,v,w,x) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8CAX-1 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro Structure of Tau filaments Type II from Subacute Sclerosing Panencephalitis · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8CAQ-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro Structure of Tau filaments Type I from Subacute Sclerosing Panencephalitis · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8Y-1 RCSB PDB | cryoem | resolution: 2.88 Å | in vitro Tau - CTE-MIA6 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9A-1 RCSB PDB | cryoem | resolution: 3.04 Å | in vitro Tau - CTE-MIA11 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8SEI-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro SF Tau from Down Syndrome · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9B4L-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands EDT Filament of Tau in complex with D-TLKIVWI, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM · Microtubule-associated protein tau (chains 0,1,A,B,C,D,M,N,O,P,Y,Z) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9BXR-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Straight Filaments purified from Down Syndrome individual brain tissue applied to graphene oxide antibody affinity grids · Microtubule-associated protein tau (chains C,D,E,F,G,H) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9BXQ-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Paired Helical Filaments purified from Down Syndrome individual brain tissue applied to graphene oxide antibody affinity grids · Microtubule-associated protein tau (chains C,D,E,F,G,H) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9BXO-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Straight Filament of tau amyloids found in Down Syndrome individuals · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9BXI-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Paired Helical Filament of tau amyloids found in Down Syndrome individuals · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9BBM-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro PHF filament generated from 4E-Tau(297-407) under neutral Mg2+ condition · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9BBL-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro THF filament generated from 4E-Tau(297-407) under neutral Mg2+ condition · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9B4O-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro Alzheimer's Tau Paired Helical Filaments, determined by CryoEM, before addition of D-peptide disaggregants · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9B4N-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro Filament of Tau in complex with D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9B4M-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Filament of Tau in complex with D-TLKIVWS, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9B3C-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro · ligands 8VH, NH2 type 2 KD-mxyl filament of miniature tau macrocycle derived from 4R tauopathic fold · Microtubule-associated protein tau (chains A,C,E,G,I,K,M,O,Q,S,U,W,Y,a,c) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9B3A-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands 8VH, NH2 filament of type 1 KD-mxyl miniature tau macrocycle derived from 4R tauopathic fold · Microtubule-associated protein tau (chains A,C,E,G,I,K,M,O,Q,S,U,W,Y,a,c) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9AXZ-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands A1AHG geranine G-induced 2N4R tau filaments · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8ZZX-1 RCSB PDB | integrative | structure | in vitro Insight into the structure of the unstructured tau protein · tau protein (chains A) | unmapped |
| EV-PDB-8ZX6-1 RCSB PDB | cryoem | resolution: 3.5 Å | in vitro Heparin bound Tau fibril PHF · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8ZWM-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Heparin bound Tau fibril polymorph 4 · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8ZWL-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Heparin bound Tau fibril polymorph 3 · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8WCP-1 RCSB PDB | cryoem | resolution: 3.28 Å | in vitro Cryo-EM structure of human disease-associated P301L Tau amyloid fibril from mouse brain · P301L Tau amyloid fibril from rTg4510 mice (chains A,B,C) | amyloid filament · rule:tau-filament-title · high Structure titled as a filament or fibril. |
| EV-PDB-8V1N-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Cryo-EM structure of tau filaments made from jR2R3-P301L peptides induced with heparin · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8UQ7-1 RCSB PDB | cryoem | resolution: 2.31 Å | in vitro · ligands X6R Alzheimer's disease PHF complexed with PET ligand MK-6240 · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8TTN-1 RCSB PDB | cryoem | resolution: 2.4 Å | in vitro PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E) · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8TTL-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro AT8-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S202E, T205E, S208E) · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8SEH-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro PHF Tau from Down Syndrome · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8R3T-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Cofactor-free Tau 4R2N isoform · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8QJJ-1 RCSB PDB | cryoem | resolution: 3.35 Å | in vitro CTE type II (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8QDV-2 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C Structure of 14-3-3 zeta delta C with the bivalent tau-pS214-pS324 peptide · Microtubule-associated protein tau (chains C,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8QCR-1 RCSB PDB | cryoem | resolution: 2.75 Å | in vitro Tau - CTE-MIA12 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,C,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8QCP-1 RCSB PDB | cryoem | resolution: 3.21 Å | in vitro Tau - AD-LIA8 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9O-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro CTE tau intermediate amyloid (LIA-17) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9M-1 RCSB PDB | cryoem | resolution: 2.65 Å | in vitro Tau - CTE-type I (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9L-1 RCSB PDB | cryoem | resolution: 2.76 Å | in vitro Tau - CTE-LIA14 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9K-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro Tau - CTE-LIA13 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9J-1 RCSB PDB | cryoem | resolution: 2.96 Å | in vitro Tau - CTE-LIA7 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9I-1 RCSB PDB | cryoem | resolution: 2.56 Å | in vitro Tau - CTE-LIA6 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,C,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9H-1 RCSB PDB | cryoem | resolution: 2.18 Å | in vitro Tau - CTE-LIA4 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9G-1 RCSB PDB | cryoem | resolution: 2.65 Å | in vitro Tau - CTE-LIA5 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9F-1 RCSB PDB | cryoem | resolution: 1.91 Å | in vitro Tau - CTE-LIA3 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,c) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9E-1 RCSB PDB | cryoem | resolution: 2.97 Å | in vitro Tau - CTE-MIA18 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9D-1 RCSB PDB | cryoem | resolution: 3.16 Å | in vitro Tau - CTE-MIA15 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9C-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Tau - CTE-MIA14 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q9B-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro Tau - CTE-MIA13 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q99-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro Tau - CTE-MIA10 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q98-1 RCSB PDB | cryoem | resolution: 1.75 Å | in vitro Tau - CTE-MIA8 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q97-1 RCSB PDB | cryoem | resolution: 2.99 Å | in vitro Tau - CTE-MIA9 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q92-1 RCSB PDB | cryoem | resolution: 3.05 Å | in vitro P301S Tau Filaments from the Brains of PS19 Transgenic Mouse Line · Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8Z-1 RCSB PDB | cryoem | resolution: 3.16 Å | in vitro Tau - CTE-MIA7 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-8Q8X-1 RCSB PDB | cryoem | resolution: 2.54 Å | in vitro Tau - CTE-MIA5 (tau intermediate amyloid) · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9QNK-2 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · ligands CA, CL, MG Tau pT245 phosphopeptide binding to 14-3-3sigma · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9PVA-1 RCSB PDB | cryoem | resolution: 3.7 Å | in vitro 295-330 S320F tau · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9PGO-1 RCSB PDB | cryoem | resolution: 2.29 Å | in vitro Cryo-EM structure of brain-derived Tau fibril from Alzheimers disease patient tissue · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9OFW-1 RCSB PDB | cryoem | resolution: 2.7 Å | in vitro 328-363 tau mutant S341L_S352I · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O8H-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro · ligands CL amyloid fibril of recombinant full-length 2N4R tau complexed with mouse liver 18S ribosomal RNA · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O8E-1 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro amyloid fibril of recombinant full-length 2N4R tau complexed with unfractionated mouse liver RNA and seeded by Alzheimer's disease tau fibrils · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O7C-1 RCSB PDB | cryoem | resolution: 2.31 Å | in vitro Recombinant AD THF incubated with DMSO (Flat Backbone E342) · Microtubule-associated protein tau (chains S,T,U,V,W,i,j,k,l,m,n,o,p,q,r) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O7B-1 RCSB PDB | cryoem | resolution: 2.31 Å | in vitro Recombinant AD THF incubated with DMSO (Kinked Backbone E342) · Microtubule-associated protein tau (chains O,P,Q,R,S,W,X,Y,Z,a,d,e,f,g,h) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O79-1 RCSB PDB | cryoem | resolution: 2.55 Å | in vitro Recombinant AD PHF incubated with DMSO (Kinked Backbone E342) · Microtubule-associated protein tau (chains F,G,H,I,J,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O76-1 RCSB PDB | cryoem | resolution: 2.58 Å | in vitro · ligands A1B91 Recombinant AD THF complexed with SW-MK-NBD (Secondary Binding Site) · Microtubule-associated protein tau (chains O,P,Q,R,S,V,W,X,Y,Z,b,c,d,e,f) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O6Z-1 RCSB PDB | cryoem | resolution: 2.31 Å | in vitro · ligands A1B91 Recombinant AD THF with SW-MK-NBD complexed in AD-related Binding Site · Microtubule-associated protein tau (chains N,O,P,Q,R,V,W,X,Y,Z,b,c,d,e,f) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O6Y-1 RCSB PDB | cryoem | resolution: 2.72 Å | in vitro · ligands A1B91 Recombinant AD PHF complexed with SW-MK-NBD · Microtubule-associated protein tau (chains K,L,M,N,O,R,S,Z,a,b) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O6X-1 RCSB PDB | cryoem | resolution: 2.58 Å | in vitro Recombinant AD THF incubated with SW-MK-NBD (Non-Symmetric Binding) · Microtubule-associated protein tau (chains R,S,T,U,V,W,X,Y,Z,a,e,f,g,h,i) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O6W-1 RCSB PDB | cryoem | resolution: 2.67 Å | in vitro Recombinant AD PHF complexed with SW-MK-NBD (Non Symmetric Binding Site) · Microtubule-associated protein tau (chains F,G,H,I,J,N,O,P,Q,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9O6V-1 RCSB PDB | cryoem | resolution: 2.72 Å | in vitro · ligands A1B91 Recombinant AD PHF complexed with SW-MK-NBD (PHF2) · Microtubule-associated protein tau (chains F,G,H,I,J,N,O,P,Y,Z) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9MR8-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Structure of D421-Truncated Tau Fibril · Microtubule-associated protein tau (chains C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9MC2-1 RCSB PDB | cryoem | resolution: 3.55 Å | in vitro Cryo-EM structure of dopaminated Tau fibril · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9HBB-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Recombinant tau PHF filaments (peptide synthesis 291-391) · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9H5J-1 RCSB PDB | cryoem | resolution: 2.72 Å | in vitro PAD12 0N3R tau PHF seeded by AD · Isoform Fetal-tau of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9H5G-1 RCSB PDB | cryoem | resolution: 2.48 Å | in vitro PAD12 0N3R:0N4R tau PHF · Isoform Fetal-tau of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9GHK-2 RCSB PDB | xray | resolution: 1.42 Å | in vitro · -173.15 °C · ligands NA Crystal structure of Fyn SH3 domain/tau 214-220 peptide complex · Tau peptide ARG-THR-PRO-SER-LEU-PRO-THR-PRO-PRO-THR (chains Q) | unmapped |
| EV-PDB-9GGA-2 RCSB PDB | xray | resolution: 2.24 Å | in vitro · -173.15 °C · ligands A1IKS Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer FM089 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9GG8-2 RCSB PDB | xray | resolution: 1.1 Å | in vitro · -173.15 °C · ligands TW8 Crystal structure of 14-3-3 sigma dC - C38N in complex with Tau pS214 peptide and covalent stabilizer 187 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9GG7-2 RCSB PDB | xray | resolution: 1.24 Å | in vitro · -173.15 °C · ligands TW8 Crystal structure of 14-3-3 sigma dC - C38N in complex with Tau pS324 peptide and covalent stabilizer 187 · Isoform Tau-G of Microtubule-associated protein tau (chains C,P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9GG6-1 RCSB PDB | cryoem | resolution: 3.36 Å | in vitro P301T type II tau filaments from human brain · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9GG1-1 RCSB PDB | cryoem | resolution: 2.26 Å | in vitro P301T type I tau filaments from human brain · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9GG0-1 RCSB PDB | cryoem | resolution: 2.81 Å | in vitro P301L tau filaments from human brain · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9GFA-2 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · ligands A1IKN Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer LD33 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9G13-2 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173.15 °C · pH 7 VHH H3-2 in complex with Tau C-terminal peptide · Isoform Tau-F of Microtubule-associated protein tau (chains B,D,F,H) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9FVP-2 RCSB PDB | xray | resolution: 1.58 Å | in vitro · -173.15 °C · ligands A1IGF Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer JS24 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9FVN-2 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · ligands A1IGH Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer NZ4 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9FVI-2 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · ligands A1IF4 Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer JS18 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9FVH-2 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · ligands A1IF5 Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer JS17 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9FVG-2 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · ligands A1IF3 Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer AO184 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9FS4-2 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · ligands TJ8 Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer LD12 · Microtubule-associated protein tau (chains P) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9FH6-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro Cryo-EM Structure of Tau Filaments from Individuals Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9ERO-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro CTE type III tau filament from vacuolar tauopathy · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9ERN-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro CTE type II tau filament from vacuolar tauopathy · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9ERM-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro CTE type I tau filament from vacuolar tauopathy · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9EOH-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro PHF type tau filament from in vitro V337M mutant · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9EOG-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro PHF type tau filament from R406W mutant · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9EOE-1 RCSB PDB | cryoem | resolution: 2.3 Å | in vitro TF type tau filament from V337M mutant · Isoform Tau-F of Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9EO9-1 RCSB PDB | cryoem | resolution: 3.3 Å | in vitro SF type tau filament from V337M mutant · Isoform Tau-F of Microtubule-associated protein tau (chains A,B) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9EO7-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro PHF type tau filament from V337M mutant · Isoform Tau-F of Microtubule-associated protein tau (chains A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9DME-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro · ligands 8VH Type 3 KD-mxyl filament of miniature tau macrocycle derived from 4R tauopathic fold · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9DA8-3 RCSB PDB | cryoem | resolution: 2.94 Å | in vitro · ligands GDP, GTP, MG, TA1 Tau-Microtubule structure in the presence of ATP · Microtubule-associated protein tau (chains D,N) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9CZL-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro Straight tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques · Isoform Tau-C of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9CZI-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro Paired helical tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9CGZ-1 RCSB PDB | cryoem | resolution: 2.69 Å | in vitro Alzheimer's Disease Seeded Mixed 0N4R and 0N3R Tau Fibrils · Isoform Fetal-tau of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9CGX-1 RCSB PDB | cryoem | resolution: 2.97 Å | in vitro Alzheimer's Disease Seeded 0N3R Tau Fibrils · Isoform Fetal-tau of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9R8D-1 RCSB PDB | cryoem | resolution: 3 Å | in vitro SF tau filament from the brain of a football player · Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9SHS-1 RCSB PDB | cryoem | resolution: 3.4 Å | in vitro Head to Head tau filament with the Alzheimer's fold · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,G) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9Z0S-3 RCSB PDB | xray | resolution: 2.55 Å | in vitro · -173.15 °C Fab/epitope complex structure of anti-Tau monoclonal antibody PHF-1 · Microtubule-associated protein tau (chains C,F,J,N,P,R) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9WIT-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Cryo-EM structure of recombinant mutant tau filaments · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9TZX-1 RCSB PDB | cryoem | resolution: 2.75 Å | in vitro Cryo-EM structure of a tau filament · Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9S2B-1 RCSB PDB | cryoem | resolution: 2.9 Å | in vitro 297-441 delta392-395 tau filaments · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9R8A-1 RCSB PDB | cryoem | resolution: 2.5 Å | in vitro PHF tau filament from the brain of a football player · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9R89-1 RCSB PDB | cryoem | resolution: 3.2 Å | in vitro CTE Type II tau filament from the brain of a football player · Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9R88-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro CTE Type I tau filament from the brain of a football player · Microtubule-associated protein tau (chains A,B,C,D,E) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9R2H-1 RCSB PDB | cryoem | resolution: 2.6 Å | in vitro Tau filaments seeded by AD homogenate using 0N3R C322S · Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-PDB-9R2F-1 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro Tau filaments seeded by AD homogenate using 0N3R C322A · Isoform Fetal-tau of Microtubule-associated protein tau (chains A,B,C,D,E,F) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-BMRB-17945 BMRB | nmr_shifts | chemical_shift | in vitro · 19.85 °C · pH 6.6 NMR backbone assignment of a Tau protein fragment · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-19253 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7.4 Backbone and Cbeta assignments for tau K18 in free and SDS micelle-bound states · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-25475 BMRB | nmr_shifts | chemical_shift | in vitro · 4.85 °C · pH 6.8 Structure of Tau(267-312) bound to Microtubules · BMRB data: 1H chemical shifts | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-BMRB-31059 BMRB | nmr_shifts | chemical_shift | in vitro · 13.85 °C · pH 5.5 Tau (297-391) in vitro untwisted fibril · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-31074 BMRB | nmr_shifts | chemical_shift | in vitro · 21.85 °C · pH 7.4 Temperature-dependent structures of tau aggregates · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-31075 BMRB | nmr_shifts | chemical_shift | in vitro · 11.85 °C · pH 7.4 Temperature-dependent structures of tau aggregates · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-BMRB-34098 BMRB | nmr_shifts | chemical_shift | in vitro · 4.85 °C · pH 6.8 Structure of Tau(254-290) bound to F-actin · BMRB data: 1H chemical shifts | unmapped |
| EV-BMRB-34099 BMRB | nmr_shifts | chemical_shift | in vitro · 4.85 °C · pH 6.8 Structure of Tau(292-319) bound to F-actin · BMRB data: 1H chemical shifts | unmapped |
| EV-BMRB-34129 BMRB | nmr_shifts | chemical_shift | in vitro · 4.85 °C · pH 6.8 Structure of Tau(254-268) bound to F-actin · BMRB data: 1H chemical shifts | unmapped |
| EV-BMRB-51483 BMRB | nmr_shifts | chemical_shift | in vitro · -0.15 °C · pH 7 Solid-state NMR assignment of fibrils formed by tau(297-391) · BMRB data: 13C chemical shifts, 15N chemical shifts | unmapped |
| EV-SASBDB-SASD2E7 SASBDB | saxs_sans | radius_of_gyration: 2.662 nm ± 0.071 | in vitro · 20 °C · pH 7.4 Tau preaggregation conformation of trunctated tau proteins · Microtubule-associated protein tau | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SASBDB-SASDLS4 SASBDB | saxs_sans | radius_of_gyration: 4.64 nm ± 0.04 | in vitro · 20 °C · pH 7.4 The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau · Microtubule-associated protein tau, Tau35 fragment | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SASBDB-SASDLT4 SASBDB | saxs_sans | radius_of_gyration: 6.33 nm ± 0.28 | in vitro · 20 °C · pH 7.4 The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau · Microtubule-associated protein tau, 2N3R isoform | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SASBDB-SASDLU4 SASBDB | saxs_sans | radius_of_gyration: 6.72 nm ± 0.28 | in vitro · 20 °C · pH 7.4 The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau · Microtubule-associated protein tau, 2N4R isoform | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SASBDB-SASDV46 SASBDB | saxs_sans | radius_of_gyration: 3.53 nm ± 0.035 | in vitro · 20 °C · pH 6.8 Conformational signatures induced by ubiquitin modification in the amyloid-forming tau repeat domain. · Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SASBDB-SASDV56 SASBDB | saxs_sans | radius_of_gyration: 3.34 nm ± 0.046 | in vitro · 20 °C · pH 6.8 · ligands partner: Polyubiquitin-B Conformational signatures induced by ubiquitin modification in the amyloid-forming tau repeat domain. · Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) with Polyubiquitin-B | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SASBDB-SASDV66 SASBDB | saxs_sans | radius_of_gyration: 3.1 nm ± 0.039 | in vitro · 20 °C · pH 6.8 · ligands partner: Polyubiquitin-B Conformational signatures induced by ubiquitin modification in the amyloid-forming tau repeat domain. · Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) with Polyubiquitin-B | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SASBDB-SASDV76 SASBDB | saxs_sans | radius_of_gyration: 3.28 nm ± 0.016 | in vitro · 20 °C · pH 6.8 · ligands partner: Polyubiquitin-B, partner: Polyubiquitin-B Conformational signatures induced by ubiquitin modification in the amyloid-forming tau repeat domain. · Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) with Polyubiquitin-B, Polyubiquitin-B | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-DISPROT-DP01100r001 DisProt | saxs_sans | disorder_region: 441 residues | in vitro DisProt DP01100: disorder, residues 1-441 · residues 1-441 of isoform P10636-8; evidence: small-angle X-ray scattering evidence used in manual assertion | disordered monomer · rule:tau-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP01100r027 DisProt | ftir_raman | disorder_region: 441 residues | in vitro DisProt DP01100: disorder, residues 1-441 · residues 1-441 of isoform P10636-8; evidence: Fourier-transform infrared spectroscopy evidence used in manual assertion | disordered monomer · rule:tau-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP01100r041 DisProt | cd | disorder_region: 441 residues | in vitro DisProt DP01100: disorder, residues 1-441 · residues 1-441 of isoform P10636-8; evidence: far-UV circular dichroism evidence used in manual assertion | disordered monomer · rule:tau-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP01100r042 DisProt | saxs_sans | disorder_region: 441 residues | in vitro DisProt DP01100: disorder, residues 1-441 · residues 1-441 of isoform P10636-8; evidence: small-angle X-ray scattering evidence used in manual assertion | disordered monomer · rule:tau-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-DISPROT-DP03552r001 DisProt | saxs_sans | disorder_region: 352 residues | in vitro DisProt DP03552: disorder, residues 1-352 · residues 1-352 of isoform P10636-2; evidence: small-angle X-ray scattering evidence used in manual assertion | disordered monomer · rule:tau-disprot-disorder · medium DisProt region annotated as disorder. |
| EV-AFDB-AF-P10636-F1 AlphaFold DB | af_prediction | plddt: 49.22 pLDDT | in silico AlphaFold DB prediction AF-P10636-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-758 | unmapped |
| EV-SMASH-SMFS-000159 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.2 Label-free optical observation of disordered-to-ordered transitions in single intrinsically disordered proteins. · Tau; optical tweezers; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-000402 SMASH-BIO | force_spectroscopy | study_record | in vitro Cation-Driven Modulation of Tau Condensates: Insights into Liquid-Liquid Phase Separation and Rheological Properties. · Tau; optical tweezers; experiment class: rheology_cell | unmapped |
| EV-SMASH-SMFS-000425 SMASH-BIO | force_spectroscopy | study_record | in vitro Direct observation of conformational dynamics in intrinsically disordered proteins at the single-molecule level · Tau; optical tweezers; experiment class: nucleic_acid_protein_interaction, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-000485 SMASH-BIO | force_spectroscopy | study_record | in vitro Label-free optical observation of disordered-to-ordered transitions in single intrinsically disordered proteins · Tau; optical tweezers; experiment class: nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-001029 SMASH-BIO | force_spectroscopy | study_record | in vitro A Missing Origin of the Tau Protein Aggregation Pathway Triggered by Thermal and Biological Forces. · Tau; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-001082 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 6.9 Cholesterol in the cargo membrane amplifies tau inhibition of kinesin-1-based transport. · Tau; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-001150 SMASH-BIO | force_spectroscopy | study_record | in vitro Expanded Conformations of Monomeric Tau Initiate Its Amyloidogenesis. · Tau; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-001448 SMASH-BIO | force_spectroscopy | study_record | in vitro Cholesterol in the cargo membrane reduces kinesin-1 binding to microtubules in the presence of tau · Tau; optical tweezers; experiment class: force_generation_motor | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SMASH-SMFS-002561 SMASH-BIO | force_spectroscopy | study_record | in vitro Tau amyloidogenesis begins with a loss of its conformational polymorphism · Tau; afm smfs; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002603 SMASH-BIO | force_spectroscopy | study_record | in vitro A Disease-Causing Intronic Point Mutation C19G Alters Tau Exon 10 Splicing via RNA Secondary Structure Rearrangement. · Tau; optical tweezers; experiment class: chromatin_mechanics, rheology_cell, translation_transcription_replication, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002699 SMASH-BIO | force_spectroscopy | study_record | in vitro Dynamic structural determinants underlie the neurotoxicity of the N-terminal tau 26-44 peptide in Alzheimer's disease and other human tauopathies. · Tau; force spectroscopy unspecified; experiment class: translation_transcription_replication, unfolding_protein | unmapped |
| EV-SMASH-SMFS-002904 SMASH-BIO | force_spectroscopy | study_record | in vitro Spontaneous Rupture and Entanglement of Human Neuronal Tau Protein Induced by Piconewton Compressive Force. · Tau; afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-003324 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams. · Tau; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-003750 SMASH-BIO | force_spectroscopy | study_record | in vitro Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams · Tau; optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, nucleic_acid_protein_interaction | unmapped |
| EV-SMASH-SMFS-004207 SMASH-BIO | force_spectroscopy | study_record | in vitro Epitope mapping of monoclonal antibody HPT-101: a study combining dynamic force spectroscopy, ELISA and molecular dynamics simulations. · Tau; optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004755 SMASH-BIO | force_spectroscopy | study_record | in vitro Viscoelasticity of tau proteins leads to strain rate-dependent breaking of microtubules during axonal stretch injury: predictions from a mathematical model. · Tau; afm smfs; experiment class: rheology_cell | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SMASH-SMFS-004839 SMASH-BIO | force_spectroscopy | study_record | in vitro Determining the specificity of monoclonal antibody HPT-101 to tau-peptides with optical tweezers. · Tau; optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004863 SMASH-BIO | force_spectroscopy | study_record | in vitro FACS-sorted particles reduce the data variance in optical tweezers-assisted dynamic force spectroscopy measurements. · Tau; optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005459 SMASH-BIO | force_spectroscopy | study_record | in vitro Competing interactions stabilize pro- and anti-aggregant conformations of human Tau. · Tau; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-005618 SMASH-BIO | force_spectroscopy | study_record | in vitro Proposal for Alzheimer's diagnosis using molecular buffer and bus network. · Tau; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-006168 SMASH-BIO | force_spectroscopy | study_record | in vitro Refolding dynamics of stretched biopolymers upon force quench. · Tau; afm smfs; experiment class: unfolding_nucleic_acid, unfolding_protein | unmapped |
| EV-SMASH-SMFS-006181-r0 SMASH-BIO | force_spectroscopy | rupture_force: 27 pN | in vitro Single molecular pair interactions between hydrophobically modified hydroxyethyl cellulose and amylose determined by dynamic force spectroscopy. · Tau; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006222 SMASH-BIO | force_spectroscopy | study_record | in vitro Tau aggregation followed by atomic force microscopy and surface plasmon resonance, and single molecule tau-tau interaction probed by atomic force spectroscopy. · Tau; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006502 SMASH-BIO | force_spectroscopy | study_record | in vitro Tuning microtubule-based transport through filamentous MAPs: the problem of dynein. · Tau; optical tweezers; experiment class: force_generation_motor | microtubule-bound · rule:tau-microtubule-title · medium Structure titled as bound to microtubules. |
| EV-SMASH-SMFS-006543 SMASH-BIO | force_spectroscopy | study_record | in vitro Contour length and refolding rate of a small protein controlled by engineered disulfide bonds. · Tau; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006684 SMASH-BIO | force_spectroscopy | study_record | in vitro Refolding upon force quench and pathways of mechanical and thermal unfolding of ubiquitin. · Tau; force spectroscopy unspecified; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006870 SMASH-BIO | force_spectroscopy | study_record | in vitro Power laws in microrheology experiments on living cells: Comparative analysis and modeling. · Tau; optical tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006978 SMASH-BIO | force_spectroscopy | study_record | in vitro Effects of salicylate on plasma membrane mechanics. · Tau; optical tweezers; experiment class: membrane_mechanics | unmapped |
| EV-SMASH-SMFS-007045 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing protein-protein interactions by dynamic force correlation spectroscopy. · Tau; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-007102 SMASH-BIO | force_spectroscopy | study_record | in vitro A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin. · Tau; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007114 SMASH-BIO | force_spectroscopy | study_record | in vitro Chemistry on a single protein, vascular cell adhesion molecule-1, during forced unfolding. · Tau; force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-007255 SMASH-BIO | force_spectroscopy | study_record | in vitro Equilibrium and transition between single- and double-headed binding of kinesin as revealed by single-molecule mechanics. · Tau; force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-007398 SMASH-BIO | force_spectroscopy | study_record | in vitro The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin molecules. · Tau; optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007472 SMASH-BIO | force_spectroscopy | study_record | in vitro Characterization of single actomyosin rigor bonds: load dependence of lifetime and mechanical properties. · Tau; optical tweezers; experiment class: force_generation_motor | unmapped |
| EV-SMASH-SMFS-007683 SMASH-BIO | force_spectroscopy | study_record | in vitro Relaxation of a single DNA molecule observed by optical microscopy. · Tau; optical tweezers; experiment class: unfolding_protein | unmapped |
Conflicts
- tau-microtubule · radius_of_gyration: 3.34, 3.1 nm · EV-SASBDB-SASDV56, EV-SASBDB-SASDV66
differ by 0.24 nm, beyond combined uncertainty 0.0603
Downloads
- Protein bundle (JSON)
- tau-filament-cif (mmCIF, observed)
- tau-filament-pdb (PDB, observed)
- tau-microtubule-cif (mmCIF, observed)
- tau-microtubule-pdb (PDB, observed)
- Curation file (YAML)