Spectrin alpha chain, non-erythrocytic 1
UniProt P07751 · gene SPTAN1 · Gallus gallus · 2477 residues
77evidence items
49mapped to a state
2states
9techniques
5sources
0conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | nmr_structure | nmr_dynamics | nmr_shifts | saxs_sans | integrative | af_prediction | md | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| native fold SH3-native | observed | proc 38 | · | proc 11 | · | · | · | · | · | · | 49 |
| unfolded SH3-unfolded | inferred | · | · | · | · | · | · | · | · | · | 0 |
Unmapped evidence: 28 of 77 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 7 | 0 |
| MDDB | 4 | 0 |
| RCSB PDB | 64 | 49 |
| SASBDB | 1 | 0 |
Curated rules applied
sh3-structures-native: 48 items
Structure
Choose a state. Each model is badged observed or inferred; assumptions are one click away.
States and transitions
| State | Basis | Parent | Description |
|---|---|---|---|
| native fold SH3-native | observed | — | Native fold of the alpha-spectrin SH3 domain, as in 1SHG. |
| unfolded SH3-unfolded | inferred | — | Unfolded ensemble reached by denaturant, temperature or force. No observed structure.Assumptions (2)
|
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-3M0S-1 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 7 · ligands SO4 Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 7 · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-5IHN-1 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 6 · ligands FMT, NA Crystal Structure of the alpha spectrin SH3 domain mutant N47G · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-5IHK-1 RCSB PDB | xray | resolution: 1.35 Å | in vitro · -173.15 °C · pH 5 · ligands ACT, PRO, SO4 Crystal Structure of the alpha spectrin SH3 domain mutant N47A · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-5IHI-1 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · pH 5 · ligands PEG, SO4 Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-4F17-1 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · pH 9 Crystal Structure of the alpha spectrin SH3 domain at pH 9 · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-4F16-1 RCSB PDB | xray | resolution: 1.93 Å | in vitro · -173.15 °C · pH 5 Crystal Structure of the alpha spectrin SH3 domain at pH 5 · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-3NGP-1 RCSB PDB | xray | resolution: 1.084 Å | in vitro · -173.15 °C · pH 6.5 High resolution structure of alpha-spectrin SH3 domain mutant with a redesigned core · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-3M0U-1 RCSB PDB | xray | resolution: 1.1 Å | in vitro · -173.15 °C · pH 6.5 · ligands FMT Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Hexagonal crystal obtained in sodium formate at pH 6.5. · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-3M0T-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 9 · ligands SO4 Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 9. · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-3M0R-1 RCSB PDB | xray | resolution: 1.1 Å | in vitro · -173.15 °C · pH 6 · ligands SO4 Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 6. · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-3M0Q-1 RCSB PDB | xray | resolution: 1.75 Å | in vitro · -173.15 °C · pH 5 · ligands SO4 Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 5. · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-3M0P-1 RCSB PDB | xray | resolution: 2.6 Å | in vitro · -173.15 °C · pH 4 · ligands SO4 Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 4. · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-3I9Q-1 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · pH 6.5 · ligands SO4 Crystal Structure of the triple mutant S19G-P20D-R21S of alpha spectrin SH3 domain · Spectrin alpha chain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2ROT-1 RCSB PDB | nmr_structure | structure | in vitro · 25.85 °C · pH 3.5 Structure of chimeric variant of SH3 domain- SHH · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2RMO-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 4 Solution structure of alpha-spectrin_SH3-bergerac from Chicken · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2OAW-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 4.6 · ligands CL Structure of SHH variant of "Bergerac" chimera of spectrin SH3 · Spectrin alpha chain, brain (chains A,B,C,D) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2NUZ-1 RCSB PDB | xray | resolution: 1.85 Å | in vitro · 19.85 °C · pH 7.2 crystal structure of alpha spectrin SH3 domain measured at room temperature · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2LJ3-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6.5 PFBD: High-throughput Strategy of Backbone fold Determination for small well-folded proteins in less than a day · Spectrin alpha chain, brain (chains A) | unmapped |
| EV-PDB-2KXD-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 4 The structure of SH3-F2 · 11-mer peptide,Spectrin alpha chain, non-erythrocytic 1,Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2KR3-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 3.5 Solution structure of SHA-D · Spectrin alpha chain, brain (chains A) | unmapped |
| EV-PDB-2JMC-1 RCSB PDB | nmr_structure | structure | in vitro · 30 °C · pH 3.5 Chimer between Spc-SH3 and P41 · Spectrin alpha chain, brain and P41 peptide chimera (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2JMA-1 RCSB PDB | nmr_structure | structure | in vitro · 26.85 °C · pH 3.5 R21A Spc-SH3:P41 complex · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2JM9-1 RCSB PDB | nmr_structure | structure | in vitro · 26.85 °C · pH 3.5 R21A Spc-SH3 bound · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2JM8-1 RCSB PDB | nmr_structure | structure | in vitro · 26.85 °C · pH 3.5 R21A Spc-SH3 free · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2F2X-1 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 3 · ligands SO4 alpha-spectrin SH3 domain R21G mutant · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2F2W-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 3 · ligands SO4 alpha-spectrin SH3 domain R21A mutant · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2F2V-1 RCSB PDB | xray | resolution: 1.85 Å | in vitro · -173.15 °C · pH 6.5 · ligands FMT alpha-spectrin SH3 domain A56G mutant · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-2CDT-1 RCSB PDB | xray | resolution: 2.54 Å | in vitro · -173.15 °C · pH 6 alpha-SPECTRIN SH3 DOMAIN A56S MUTANT · SPECTRIN ALPHA CHAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1UUE-1 RCSB PDB | xray | resolution: 2.6 Å | in vitro · -173.15 °C · pH 7 a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT) · SPECTRIN ALPHA CHAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1U5P-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 8.5 · ligands K, PO4 Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin · Spectrin alpha chain, brain (chains A) | unmapped |
| EV-PDB-1U4Q-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · pH 8.5 Crystal Structure of Repeats 15, 16 and 17 of Chicken Brain Alpha Spectrin · Spectrin alpha chain, brain (chains A,B) | unmapped |
| EV-PDB-1U06-1 RCSB PDB | xray | resolution: 1.49 Å | in vitro · -173.15 °C · pH 7.2 · ligands AZI crystal structure of chicken alpha-spectrin SH3 domain · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1TUD-1 RCSB PDB | xray | resolution: 1.77 Å | in vitro ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48 · ALPHA-SPECTRIN (chains A) | unmapped |
| EV-PDB-1TUC-1 RCSB PDB | xray | resolution: 2.02 Å | in vitro ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20 · ALPHA-SPECTRIN (chains A) | unmapped |
| EV-PDB-1SHG-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro CRYSTAL STRUCTURE OF A SRC-HOMOLOGY 3 (SH3) DOMAIN · ALPHA-SPECTRIN SH3 DOMAIN (chains A) | native fold · curator:draft (unreviewed) · high Representative native structure; title and UniProt mapping checked against RCSB. |
| EV-PDB-1QKX-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173.15 °C · pH 6 Alpha-spectrin Src Homology 3 domain, N47A mutant in the distal loop. · SPECTRIN ALPHA CHAIN (chains A) | unmapped |
| EV-PDB-1QKW-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 6 · ligands GOL, SO4 Alpha-spectrin Src Homology 3 domain, N47G mutant in the distal loop. · ALPHA II SPECTRIN (chains A) | unmapped |
| EV-PDB-1PWT-1 RCSB PDB | xray | resolution: 1.77 Å | in vitro · 13.85 °C · pH 4 THERMODYNAMIC ANALYSIS OF ALPHA-SPECTRIN SH3 AND TWO OF ITS CIRCULAR PERMUTANTS WITH DIFFERENT LOOP LENGTHS: DISCERNING THE REASONS FOR RAPID FOLDING IN PROTEINS · ALPHA SPECTRIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1NEG-1 RCSB PDB | xray | resolution: 2.3 Å | in vitro · -163.15 °C · pH 6.5 · ligands AZI Crystal Structure Analysis of N-and C-terminal labeled SH3-domain of alpha-Chicken Spectrin · Spectrin alpha chain, brain (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1M8M-1 RCSB PDB | nmr_structure | structure | in vitro · 6.85 °C · pH 7.5 SOLID-STATE MAS NMR STRUCTURE OF THE A-SPECTRIN SH3 DOMAIN · SPECTRIN ALPHA CHAIN, BRAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1HD3-1 RCSB PDB | xray | resolution: 1.98 Å | in vitro · -173.15 °C · pH 6 · ligands GOL, SO4 A-SPECTRIN SH3 DOMAIN F52Y MUTANT · SPECTRIN ALPHA CHAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1H8K-1 RCSB PDB | xray | resolution: 2.7 Å | in vitro · -173.15 °C · pH 4.5 A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT · SPECTRIN ALPHA CHAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1G2B-1 RCSB PDB | xray | resolution: 1.12 Å | in vitro · -173.15 °C · ligands SO4 ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48 · SPECTRIN ALPHA CHAIN (chains A) | unmapped |
| EV-PDB-1E7O-1 RCSB PDB | xray | resolution: 3.2 Å | in vitro · -173.15 °C · pH 6 · ligands GOL A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V44I, V58L MUTATIONS · SPECTRIN ALPHA CHAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1E6H-1 RCSB PDB | xray | resolution: 2.01 Å | in vitro · -173.15 °C · pH 6 A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS · SPECTRIN ALPHA CHAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1E6G-1 RCSB PDB | xray | resolution: 2.3 Å | in vitro · -173.15 °C · pH 6 · ligands SO4 A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT · SPECTRIN ALPHA CHAIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1CUN-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -165.15 °C · pH 5.6 CRYSTAL STRUCTURE OF REPEATS 16 AND 17 OF CHICKEN BRAIN ALPHA SPECTRIN · PROTEIN (ALPHA SPECTRIN) (chains A,B,C) | unmapped |
| EV-PDB-1BK2-1 RCSB PDB | xray | resolution: 2.01 Å | in vitro · -173.15 °C · pH 6 A-SPECTRIN SH3 DOMAIN D48G MUTANT · A-SPECTRIN (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-1AJ3-1 RCSB PDB | nmr_structure | structure | in vitro · 34.85 °C · pH 6 SOLUTION STRUCTURE OF THE SPECTRIN REPEAT, NMR, 20 STRUCTURES · ALPHA SPECTRIN (chains A) | unmapped |
| EV-PDB-1AEY-1 RCSB PDB | nmr_structure | structure | in vitro · 23.85 °C · pH 3.5 ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES · ALPHA-SPECTRIN (chains A) | unmapped |
| EV-PDB-5M6S-1 RCSB PDB | cryoem | resolution: 4.8 Å | in vitro folding intermediate of spectrin R16 · spectrin (chains A) | unmapped |
| EV-PDB-8CF4-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7 SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the combined correction method with PDB 2NUZ · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-8CHG-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7 SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction for dipolar truncation with PDB 2NUZ · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-8CHH-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7 SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction method for spin-diffusion with PDB 2NUZ as reference · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9EYB-1 RCSB PDB | xray | resolution: 1.337 Å | in vitro · -193.15 °C · pH 7 · ligands GOL, PO4 A-SPECTRIN SH3 DOMAIN V9L, A11V, V23L, M25C, V46W, V53L and V58L MUTANT · Spectrin alpha chain, non-erythrocytic 1 (chains AAA) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9EYC-1 RCSB PDB | xray | resolution: 1.06 Å | in vitro · -193.15 °C · pH 6.5 · ligands GOL, PO4 A-SPECTRIN SH3 DOMAIN V9L, A11V, V23L, M25C, V46W, V53L and V58L MUTANT · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9EYE-1 RCSB PDB | xray | resolution: 1.13 Å | in vitro · -193.15 °C · pH 6.5 · ligands GOL, PO4 A-SPECTRIN SH3 DOMAIN V9L, A11V, L31V, V44I, V53I MUTANT · Spectrin alpha chain, non-erythrocytic 1 (chains AAA) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9EYF-1 RCSB PDB | xray | resolution: 1.34 Å | in vitro · -193.15 °C · pH 6.8 A-SPECTRIN SH3 DOMAIN V9L, A11V, V23L, M25L, V46Y, V53I MUTANT · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9IH6-1 RCSB PDB | xray | resolution: 1.31 Å | in vitro · -193.15 °C · pH 6.5 · ligands GOL A-SPECTRIN SH3 DOMAIN V9Y, A11V, V23L, M25V, V53L, V58L MUTANT · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9IH7-1 RCSB PDB | xray | resolution: 1.12 Å | in vitro · -193.15 °C · pH 6.5 · ligands SO4 A-SPECTRIN SH3 DOMAIN V9L, A11V, V23I, M25V, V46F, V53L, V58L MUTANT · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9IHA-1 RCSB PDB | xray | resolution: 1.013 Å | in vitro · -193.15 °C · pH 6.5 · ligands SO4 A-SPECTRIN SH3 DOMAIN V9L, A11V, M25V, V46F, V58L MUTANT · Spectrin alpha chain, non-erythrocytic 1 (chains AAA) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-PDB-9A3E-1 RCSB PDB | integrative | structure | in vitro Structure of SH3 domain from chicken alpha spectrin determined using restraints from solid-state NMR · spectrin alpha chain (chains A) | unmapped |
| EV-PDB-9A0A-1 RCSB PDB | integrative | structure | in vitro Protein motional details and dynamics of spectrin alpha chain · spectrin alpha chain (chains A) | unmapped |
| EV-PDB-7S4R-1 RCSB PDB | xray | resolution: 2.1 Å | in vitro · 24.85 °C Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - alpha Spectrin-SH3 domain · Spectrin alpha chain, non-erythrocytic 1 (chains A) | native fold · rule:sh3-structures-native · medium Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title. |
| EV-BMRB-15013 BMRB | nmr_shifts | chemical_shift | in vitro · 29.85 °C · pH 3.5 Chimer between Spc-SH3 and P41 · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-15144 BMRB | nmr_dynamics | relaxation_rate | in vitro · 9.85 °C · pH 3.5 Side-chain relaxation in SH3 domain from alpha-spectrin measured at multiple temperatures · BMRB data: order parameters, T1 relaxation values, T2 relaxation values | unmapped |
| EV-BMRB-17915 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.5 PFBD: High-throughput Strategy of Backbone fold Determination for small well-folded proteins in less than a day · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-18260 BMRB | nmr_dynamics | relaxation_rate | in vitro · 24.85 °C · pH 6.8 1H, 13C and 15N resonance assignment of chicken brain alpha spectrin repeat 17 · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts, T1 relaxation values, T2 relaxation values, coupling constants | unmapped |
| EV-BMRB-34785 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 7 SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the combined correction method with PDB 2NUZ · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-7305 BMRB | nmr_shifts | chemical_shift | in vitro · 26.85 °C · pH 3.5 R21A Spc-SH3 free · BMRB data: 1H chemical shifts | unmapped |
| EV-BMRB-7306 BMRB | nmr_shifts | chemical_shift | in vitro · 26.85 °C · pH 3.5 R21A Spc-SH3 bound · BMRB data: 1H chemical shifts | unmapped |
| EV-SASBDB-SASDJJ3 SASBDB | saxs_sans | radius_of_gyration: 1.315 nm ± 0.003 | in vitro · 25 °C · pH 3 Improving data quality and expanding BioSAXS experiments to low-molecular-weight and low-concentration protein samples. · Spectrin alpha chain, non-erythrocytic 1 | unmapped |
| EV-AFDB-AF-P07751-F1 AlphaFold DB | af_prediction | plddt: 75.62 pLDDT | in silico AlphaFold DB prediction AF-P07751-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-2477 | unmapped |
| EV-MDDB-A00HC MDDB | md | trajectory: 10 ns | in silico · 26.85 °C MoDEL 1G2B · start 1G2B; Amber Parm99 | unmapped |
| EV-MDDB-A00W4 MDDB | md | trajectory: 10 ns | in silico · 26.85 °C MoDEL 1PWT · start 1PWT; Amber Parm99 | unmapped |
| EV-MDDB-A010H MDDB | md | trajectory: 10 ns | in silico · 26.85 °C MoDEL 1SHG · start 1SHG; Amber Parm99 | unmapped |
| EV-MDDB-A012Z MDDB | md | trajectory: 10 ns | in silico · 26.85 °C MoDEL 1TUC · start 1TUC; Amber Parm99 | unmapped |
Conflicts
No conflicts found among comparable evidence.
76 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.
Downloads
- Protein bundle (JSON)
- SH3-native-cif (mmCIF, observed)
- SH3-native-pdb (PDB, observed)
- Curation file (YAML)