DNA-directed RNA polymerase II subunit RPB1

UniProt P04050 · gene RPO21 · Saccharomyces cerevisiae (strain ATCC 204508 / S288c) · 1733 residues

316evidence items
0mapped to a state
0states
8techniques
6sources
0conflicts

Coverage grid

Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).

StateBasisxraycryoemnmr_structurenmr_shiftssaxs_sansforce_spectroscopygel_electrophoresisaf_predictionTotal
No states defined yet.

Unmapped evidence: 316 of 316 items. Mappings come from curator assignments and curated rules; see About for how rules work.

Sources

SourceEvidenceMapped
AlphaFold DB10
BMRB30
DisProt50
RCSB PDB2880
SASBDB10
SMASH-BIO180

Structure

No state models are exported for this protein yet. Observed states export the representative PDB entry; inferred states need fitted models, not yet built.

States and transitions

No states defined.

StateBasisParentDescription

No transitions recorded in this version (no rate or free-energy evidence has been curated yet).

Evidence

One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.

EvidenceTechniqueObservableConditionsMapped to state
EV-PDB-1I3Q-1
RCSB PDB
xrayresolution: 3.1 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-1I6H-3
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA POLYMERASE II ELONGATION COMPLEX · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-1K83-1
RCSB PDB
xrayresolution: 2.8 Åin vitro · -173.15 °C · pH 6 · ligands MN, ZN
Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-1PQV-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · pH 7.5 · ligands MG, ZN
RNA polymerase II-TFIIS complex · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1R5U-1
RCSB PDB
xrayresolution: 4.5 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA POLYMERASE II TFIIB COMPLEX · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1R9S-3
RCSB PDB
xrayresolution: 4.25 Åin vitro · -173.15 °C · pH 6 · ligands MG, UTP, ZN
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1R9T-4
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 6 · ligands ATP, MG, ZN
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1SFO-3
RCSB PDB
xrayresolution: 3.61 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1TWA-1
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 6 · ligands ATP, MN, ZN
RNA polymerase II complexed with ATP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1TWC-1
RCSB PDB
xrayresolution: 3 Åin vitro · -173.15 °C · pH 6 · ligands GTP, MN, ZN
RNA polymerase II complexed with GTP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1TWF-1
RCSB PDB
xrayresolution: 2.3 Åin vitro · -173.15 °C · pH 6 · ligands MN, UTP, ZN
RNA polymerase II complexed with UTP at 2.3 A resolution · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1TWG-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 6 · ligands CTP, MN, ZN
RNA polymerase II complexed with CTP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1TWH-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 6 · ligands ATP, MN, ZN
RNA polymerase II complexed with 2'dATP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1WCM-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · ligands MG, ZN
Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-1Y1V-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · ligands MG, ZN
Refined RNA Polymerase II-TFIIS complex · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1Y1W-4
RCSB PDB
xrayresolution: 4 Åin vitro · ligands MG, ZN
Complete RNA Polymerase II elongation complex · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1Y77-4
RCSB PDB
xrayresolution: 4.5 Åin vitro · ligands G2P, MG, ZN
Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-24QP-1
RCSB PDB
cryoemresolution: 2.73 Åin vitro · ligands DNH, MG, PT, ZN
Structure of yeast Pol II in complex with an oxaliplatin-ICL lesion at +7 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-24QR-12
RCSB PDB
cryoemresolution: 2.67 Åin vitro · ligands DNH, MG, PT, ZN
Structure of yeast Pol II in complex with an oxaliplatin-ICL lesion at +2 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-24QS-1
RCSB PDB
cryoemresolution: 2.74 Åin vitro · ligands CPT, MG, ZN
Structure of yeast post-translocation state Pol II in complex with a cisplatin-ICL lesion at +2 position in the second ICL DNA sequence. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-24QT-1
RCSB PDB
cryoemresolution: 2.96 Åin vitro · ligands CPT, MG, ZN
Structure of yeast pre-translocation state Pol II in complex with a cisplatin-ICL lesion at +2 position in the second ICL DNA sequence. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-29RF-1
RCSB PDB
cryoemresolution: 3.02 Åin vitro · ligands GTP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with NTP-state-III · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-2B63-2
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · ligands MG, ZN
Complete RNA Polymerase II-RNA inhibitor complex · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2B8K-1
RCSB PDB
xrayresolution: 4.15 Åin vitro · -173.15 °C · ligands ZN
12-subunit RNA Polymerase II · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2E2H-4
RCSB PDB
xrayresolution: 3.95 Åin vitro · -173.15 °C · pH 6.5 · ligands GTP, MG, ZN
RNA polymerase II elongation complex at 5 mM Mg2+ with GTP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2E2I-4
RCSB PDB
xrayresolution: 3.41 Åin vitro · -173.15 °C · pH 6.5 · ligands DGT, MG, ZN
RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2JA7-4
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
CPD lesion containing RNA Polymerase II elongation complex C · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A,M)
unmapped
EV-PDB-2JA8-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
CPD lesion containing RNA Polymerase II elongation complex D · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-2L0I-2
RCSB PDB
nmr_structurestructurein vitro · 24.85 °C · pH 7.4
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide · DNA-directed RNA polymerase (chains B)
unmapped
EV-PDB-2LO6-2
RCSB PDB
nmr_structurestructurein vitro · 19.85 °C · pH 8
Structure of Nrd1 CID bound to phosphorylated RNAP II CTD · DNA-directed RNA polymerase II subunit RPB1 (chains B)
unmapped
EV-PDB-2NVQ-4
RCSB PDB
xrayresolution: 2.9 Åin vitro · pH 7 · ligands DUT, MG, ZN
RNA Polymerase II Elongation Complex in 150 mM Mg+2 with 2'dUTP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2NVT-4
RCSB PDB
xrayresolution: 3.36 Åin vitro · -173.15 °C · pH 7 · ligands G2P, MG, ZN
RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2NVX-4
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · pH 6.5 · ligands DUT, MG, ZN
RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2NVY-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 6.5 · ligands MN, ZN
RNA Polymerase II form II in 150 mM Mn+2 · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2R7Z-4
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 7 · ligands CPT, MG, ZN
Cisplatin lesion containing RNA polymerase II elongation complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-2R92-3
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Elongation complex of RNA polymerase II with artificial RdRP scaffold · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-2R93-2
RCSB PDB
xrayresolution: 4 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-2VUM-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Alpha-amanitin inhibited complete RNA polymerase II elongation complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-2YU9-4
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 7 · ligands MG, UTP, ZN
RNA polymerase II elongation complex in 150 mm MG+2 with UTP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-30ES-1
RCSB PDB
cryoemresolution: 2.54 Åin vitro · ligands ATP, MG, ZN
Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State V (TL-closed), in the presence of substrate ATP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-36RS-1
RCSB PDB
cryoemresolution: 6.75 Åin vitro · ligands ZN
Cryo-EM structure of Saccharomyces cerevisiae RNA polymerase II without stalk (no Rpb4/Rpb7) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-30EP-1
RCSB PDB
cryoemresolution: 2.55 Åin vitro · ligands ATP, MG, ZN
Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State III (TL-open), in the presence of substrate ATP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-2NVZ-4
RCSB PDB
xrayresolution: 4.3 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, UTP, ZN
RNA Polymerase II elongation complex with UTP, updated 11/2006 · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-2JA6-1
RCSB PDB
xrayresolution: 4 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
CPD lesion containing RNA Polymerase II elongation complex B · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-2JA5-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
CPD lesion containing RNA Polymerase II elongation complex A · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-2E2J-4
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 6.5 · ligands G2P, MG, ZN
RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1Y1Y-3
RCSB PDB
xrayresolution: 4 Åin vitro
RNA Polymerase II-TFIIS-DNA/RNA complex · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-1NT9-1
RCSB PDB
xrayresolution: 4.2 Åin vitro · -173.15 °C · pH 6
Complete 12-subunit RNA polymerase II · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-1NIK-1
RCSB PDB
xrayresolution: 4.1 Åin vitro · -173.15 °C · pH 6.3 · ligands ZN
Wild Type RNA Polymerase II · RPB1 (chains A)
unmapped
EV-PDB-1I50-1
RCSB PDB
xrayresolution: 2.8 Åin vitro · -173.15 °C · pH 6 · ligands MN, ZN
RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION · DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
unmapped
EV-PDB-3FKI-1
RCSB PDB
xrayresolution: 3.88 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
12-Subunit RNA Polymerase II Refined with Zn-SAD data · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3GTK-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 6 · ligands ZN
Backtracked RNA polymerase II complex with 18mer RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3K7A-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -180.15 °C · pH 6.9 · ligands ZN
Crystal Structure of an RNA polymerase II-TFIIB complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3PO3-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 7 · ligands ACT, EPE, MG, PGE, ZN
Arrested RNA Polymerase II reactivation intermediate · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-4A3J-1
RCSB PDB
xrayresolution: 3.7 Åin vitro · -173.15 °C · pH 7 · ligands G2P, MG, ZN
RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3L-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 7 · ligands APC, MG, ZN
RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3K-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · ligands MG, ZN
RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3I-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
RNA Polymerase II binary complex with DNA · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3G-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3F-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 7 · ligands APC, MG, ZN
RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3E-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 7 · ligands APC, MG, ZN
RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3D-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3C-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3B-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-3S2H-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 6-nt RNA containing a 2[prime]-iodo ATP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S2D-1
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 5-nt RNA containing a 5Br-U · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S1R-1
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 6 · ligands GTP, MG, ZN
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with GTP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S1Q-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 6 · ligands ATP, MG, ZN
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S1N-1
RCSB PDB
xrayresolution: 3.1 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 2) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S1M-1
RCSB PDB
xrayresolution: 3.13 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S17-1
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 9-nt RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S16-1
RCSB PDB
xrayresolution: 3.241 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with an 8-nt RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S15-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 7-nt RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3S14-1
RCSB PDB
xrayresolution: 2.85 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 6-nt RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3RZO-1
RCSB PDB
xrayresolution: 3 Åin vitro · -173.15 °C · pH 6 · ligands ZN
RNA Polymerase II Initiation Complex with a 4-nt RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3RZD-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
RNA Polymerase II Initiation Complex with a 5-nt RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3QT1-1
RCSB PDB
xrayresolution: 4.3 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
RNA polymerase II variant containing A Chimeric RPB9-C11 subunit · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3PO2-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 7 · ligands ACT, EPE, MG, PEG, ZN
Arrested RNA Polymerase II elongation complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3M4O-1
RCSB PDB
xrayresolution: 3.57 Åin vitro · -196.15 °C · pH 6 · ligands C7P, MG, ZN
RNA polymerase II elongation complex B · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3M3Y-1
RCSB PDB
xrayresolution: 3.18 Åin vitro · -196.15 °C · pH 6 · ligands C7P, MG, ZN
RNA polymerase II elongation complex C · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3K1F-1
RCSB PDB
xrayresolution: 4.3 Åin vitro · -173.15 °C · pH 7.5 · ligands ZN
Crystal structure of RNA Polymerase II in complex with TFIIB · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3J1N-1
RCSB PDB
cryoemresolution: 16 Åin vitro
Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3J0K-1
RCSB PDB
cryoemresolution: 36 Åin vitro · ligands MG, ZN
Orientation of RNA polymerase II within the human VP16-Mediator-pol II-TFIIF assembly · DNA-directed RNA polymerase II largest subunit (chains A)
unmapped
EV-PDB-3I4N-1
RCSB PDB
xrayresolution: 3.9 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
8-oxoguanine containing RNA polymerase II elongation complex E · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3I4M-1
RCSB PDB
xrayresolution: 3.7 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
8-oxoguanine containing RNA polymerase II elongation complex D · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3HOZ-1
RCSB PDB
xrayresolution: 3.65 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3HOY-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · ligands MG, ZN
Complete RNA polymerase II elongation complex VI · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3HOX-1
RCSB PDB
xrayresolution: 3.65 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Complete RNA polymerase II elongation complex V · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3HOW-1
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3HOV-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Complete RNA polymerase II elongation complex II · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3HOU-1
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 7 · ligands ZN
Complete RNA polymerase II elongation complex I with a T-U mismatch · DNA-directed RNA polymerase II subunit RPB1 (chains A,M)
unmapped
EV-PDB-3H3V-1
RCSB PDB
xrayresolution: 4 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Yeast RNAP II containing poly(A)-signal sequence in the active site · DNA-directed RNA polymerase II subunit RPB1 (chains B)
unmapped
EV-PDB-3GTQ-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 6 · ligands ZN
Backtracked RNA polymerase II complex induced by damage · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3GTP-1
RCSB PDB
xrayresolution: 3.9 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
Backtracked RNA polymerase II complex with 24mer RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3GTO-1
RCSB PDB
xrayresolution: 4 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
Backtracked RNA polymerase II complex with 15mer RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3GTM-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
Co-complex of Backtracked RNA polymerase II with TFIIS · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3GTL-1
RCSB PDB
xrayresolution: 3.38 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
Backtracked RNA polymerase II complex with 13mer with G<>U mismatch · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3GTJ-1
RCSB PDB
xrayresolution: 3.42 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
Backtracked RNA polymerase II complex with 13mer RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3GTG-1
RCSB PDB
xrayresolution: 3.78 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
Backtracked RNA polymerase II complex with 12mer RNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-3CQZ-1
RCSB PDB
xrayresolution: 2.8 Åin vitro · ligands ZN
Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4V1N-1
RCSB PDB
cryoemresolution: 7.8 Åin vitro · ligands MG, ZN
Architecture of the RNA polymerase II-Mediator core transcription initiation complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4V1O-1
RCSB PDB
cryoemresolution: 9.7 Åin vitro · ligands MG, ZN
Architecture of the RNA polymerase II-Mediator core transcription initiation complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-5SVA-37
RCSB PDB
cryoemresolution: 15.3 Åin vitro · ligands MG, ZN
Mediator-RNA Polymerase II Pre-Initiation Complex · DNA-directed RNA polymerase II subunit RPB1 (chains k)
unmapped
EV-PDB-5SVA-1
RCSB PDB
cryoemresolution: 15.3 Åin vitro · ligands MG, ZN
Mediator-RNA Polymerase II Pre-Initiation Complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6BQF-1
RCSB PDB
xrayresolution: 3.35 Åin vitro · -173.15 °C · ligands MG, ZN
Pol II elongation complex with 'dT-AP' at i+1, i-1 position · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6O6C-1
RCSB PDB
cryoemresolution: 3.1 Åin vitro · ligands MG, ZN
RNA polymerase II elongation complex arrested at a CPD lesion · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6NPW-3
RCSB PDB
xrayresolution: 2.486 Åin vitro · -173.15 °C · ligands PO4
SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide · Ser2/Ser5 phosphorylated peptide (chains E)
unmapped
EV-PDB-6I84-7
RCSB PDB
cryoemresolution: 4.4 Åin vitro · ligands MG, ZN
Structure of transcribing RNA polymerase II-nucleosome complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6GYM-9
RCSB PDB
cryoemresolution: 6.7 Åin vitro · ligands MG, SF4, ZN
Structure of a yeast closed complex with distorted DNA (CCdist) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6GYL-1
RCSB PDB
cryoemresolution: 4.8 Åin vitro · ligands MG, ZN
Structure of a yeast closed complex with distorted DNA (core CCdist) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6GYK-1
RCSB PDB
cryoemresolution: 5.1 Åin vitro · ligands MG, ZN
Structure of a yeast closed complex (core CC1) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6BM4-1
RCSB PDB
xrayresolution: 2.951 Åin vitro · -173.15 °C · ligands 2KH, MG, ZN
Pol II elongation complex with an abasic lesion at i-1 position,soaking UMPNPP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6BM2-1
RCSB PDB
xrayresolution: 3.403 Åin vitro · -173.15 °C · ligands MG, ZN
Pol II elongation complex with an abasic lesion at i-1 position · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6BLP-1
RCSB PDB
xrayresolution: 3.203 Åin vitro · -173.15 °C · ligands APC, MG, ZN
Pol II elongation complex with an abasic lesion at i+1 position, soaking AMPCPP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6BLO-1
RCSB PDB
xrayresolution: 3.401 Åin vitro · -173.15 °C · ligands MG, ZN
Pol II elongation complex with an abasic lesion at i+1 position · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5W51-1
RCSB PDB
xrayresolution: 3.404 Åin vitro · -173.15 °C · pH 6.5 · ligands 2KH, MG, ZN
Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5W4U-1
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
Pol II elongation complex with an N6-methyladenine-containing template · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5VVS-1
RCSB PDB
cryoemresolution: 6.4 Åin vitro · ligands MG, ZN
RNA pol II elongation complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5VVR-1
RCSB PDB
cryoemresolution: 5.8 Åin vitro · ligands MG, ZN
Ternary complex of RNA Pol II, transcription scaffold and Rad26 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5VKO-2
RCSB PDB
xrayresolution: 1.8 Åin vitro · -173.15 °C · pH 7.5 · ligands IPA
SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493 · DNA-directed RNA polymerase II subunit RPB1 (chains B)
unmapped
EV-PDB-5VKL-2
RCSB PDB
xrayresolution: 2.198 Åin vitro · -173.15 °C · pH 7
SPT6 tSH2-RPB1 1476-1500 pS1493 · DNA-directed RNA polymerase II subunit RPB1 (chains B)
unmapped
EV-PDB-5U5Q-1
RCSB PDB
xrayresolution: 3.8 Åin vitro · 20 °C · pH 6.3 · ligands MG, ZN
12 Subunit RNA Polymerase II at Room Temperature collected using SFX · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5OT2-1
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 7 · ligands AHW, MG, ZN
RNA polymerase II elongation complex in the presence of 3d-Napht-A · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5OQM-1
RCSB PDB
cryoemresolution: 5.8 Åin vitro · ligands MG, SF4, ZN
STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5OQJ-1
RCSB PDB
cryoemresolution: 4.7 Åin vitro · ligands MG, SF4, ZN
STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5M9D-2
RCSB PDB
nmr_structurestructurein vitro · 24.85 °C · pH 6.8
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide · THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER (chains B)
unmapped
EV-PDB-5LVF-2
RCSB PDB
nmr_structurestructurein vitro · 19.85 °C · pH 6.8
Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide · PRO-SER-TYR-SER-PRO-PTH-SER-PRO-SER-TYR-SER-PRO-THR-SER-PRO-SER (chains B)
unmapped
EV-PDB-5IP9-1
RCSB PDB
xrayresolution: 3.9 Åin vitro · -173.15 °C · ligands MG, ZN
Structure of RNA Polymerase II-TFIIF complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5IP7-1
RCSB PDB
xrayresolution: 3.52 Åin vitro · -173.15 °C · ligands MG, ZN
Structure of RNA Polymerase II-Tfg1 peptide complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5FZ5-1
RCSB PDB
cryoemresolution: 8.8 Åin vitro · ligands MG, ZN
Transcription initiation complex structures elucidate DNA opening (CC) · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-5FYW-1
RCSB PDB
cryoemresolution: 4.35 Åin vitro · ligands MG, ZN
Transcription initiation complex structures elucidate DNA opening (OC) · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-5FMF-3
RCSB PDB
cryoemresolution: 6 Åin vitro · ligands MG, ZN
the P-lobe of RNA polymerase II pre-initiation complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-5C4X-1
RCSB PDB
xrayresolution: 4 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5C4J-1
RCSB PDB
xrayresolution: 4 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5C4A-1
RCSB PDB
xrayresolution: 4.2 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5C44-1
RCSB PDB
xrayresolution: 3.95 Åin vitro · -173.15 °C · pH 7
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-5C3E-1
RCSB PDB
xrayresolution: 3.7 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-4Y7N-1
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · pH 6 · ligands G2P, MG, ZN
The Structure Insight into 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-4Y52-1
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · pH 6 · ligands MG, ZN
Crystal structure of 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-4X6A-1
RCSB PDB
xrayresolution: 3.96 Åin vitro · -173.15 °C · ligands ZN
Crystal structure of yeast RNA polymerase II encountering oxidative Cyclopurine DNA lesions · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-4X67-1
RCSB PDB
xrayresolution: 4.1 Åin vitro · -173.15 °C · ligands ZN
Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-4V1M-1
RCSB PDB
cryoemresolution: 6.6 Åin vitro · ligands MG, ZN
Architecture of the RNA polymerase II-Mediator core transcription initiation complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4GWQ-8
RCSB PDB
xrayresolution: 4.5 Åin vitro · -173.15 °C · pH 7
Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit · DNA-directed RNA polymerase II subunit RPB1 (chains H)
unmapped
EV-PDB-4BY7-1
RCSB PDB
xrayresolution: 3.15 Åin vitro · -173.15 °C · pH 7 · ligands EPE, MG, ZN
elongating RNA Polymerase II-Bye1 TLD complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4BY1-1
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · pH 7 · ligands APC, MG, ZN
elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4BXZ-1
RCSB PDB
xrayresolution: 4.8 Åin vitro · -173.15 °C · pH 7.5 · ligands MG, ZN
RNA Polymerase II-Bye1 complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4BXX-1
RCSB PDB
xrayresolution: 3.28 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
Arrested RNA polymerase II-Bye1 complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4BBS-1
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · ligands MG, ZN
Structure of an initially transcribing RNA polymerase II-TFIIB complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4BBR-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · ligands MG, ZN
Structure of RNA polymerase II-TFIIB complex · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A93-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 7 · ligands MG, ZN
RNA Polymerase II elongation complex containing a CPD Lesion · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-4A3M-1
RCSB PDB
xrayresolution: 3.9 Åin vitro · -173.15 °C · pH 7 · ligands APC, MG, ZN
RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP · DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)
unmapped
EV-PDB-6UPZ-4
RCSB PDB
xrayresolution: 3.1 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, PPV, ZN
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6UQ0-4
RCSB PDB
xrayresolution: 3.56 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 4 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6UQ1-4
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6UQ3-4
RCSB PDB
xrayresolution: 3.47 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, PPV, ZN
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7KED-1
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
RNA polymerase II elongation complex with unnatural base dTPT3 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7KEE-1
RCSB PDB
xrayresolution: 3.45 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, WCG, ZN
RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7KEF-1
RCSB PDB
xrayresolution: 3.89 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, WC4, ZN
RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7MEI-3
RCSB PDB
cryoemresolution: 3.54 Åin vitro · ligands MG, ZN
Composite structure of EC+EC · DNA-directed RNA polymerase subunit (chains A,a)
unmapped
EV-PDB-7MK9-3
RCSB PDB
cryoemresolution: 3.54 Åin vitro · ligands MG, ZN
Complex structure of trailing EC of EC+EC (trailing EC-focused) · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-7MKA-3
RCSB PDB
cryoemresolution: 3.54 Åin vitro · ligands MG, ZN
Structure of EC+EC (leading EC-focused) · DNA-directed RNA polymerase subunit (chains a)
unmapped
EV-PDB-7ML0-1
RCSB PDB
cryoemresolution: 3 Åin vitro · ligands MG, SF4, ZN
RNA polymerase II pre-initiation complex (PIC1) · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-7ML1-12
RCSB PDB
cryoemresolution: 4 Åin vitro · ligands MG, SF4, ZN
RNA polymerase II pre-initiation complex (PIC2) · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-7ML2-1
RCSB PDB
cryoemresolution: 3.4 Åin vitro · ligands MG, SF4, ZN
RNA polymerase II pre-initiation complex (PIC3) · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-7ML4-6
RCSB PDB
cryoemresolution: 3.1 Åin vitro · ligands MG, SF4, ZN
RNA polymerase II initially transcribing complex (ITC) · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-7NKX-1
RCSB PDB
cryoemresolution: 2.9 Åin vitro · ligands ADP, BEF, MG, ZN
RNA polymerase II-Spt4/5-nucleosome-Chd1 structure · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7NKY-4
RCSB PDB
cryoemresolution: 3.2 Åin vitro · ligands MG, ZN
RNA Polymerase II-Spt4/5-nucleosome-FACT structure · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7O4I-9
RCSB PDB
cryoemresolution: 3.2 Åin vitro · ligands ADP, BEF, MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7O4K-9
RCSB PDB
cryoemresolution: 3.6 Åin vitro · ligands ADP, BEF, MG, SF4, ZN
Yeast TFIIH in the contracted state within the pre-initiation complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7O4L-9
RCSB PDB
cryoemresolution: 3.4 Åin vitro · ligands ADP, BEF, MG, SF4, ZN
Yeast TFIIH in the expanded state within the pre-initiation complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7O72-9
RCSB PDB
cryoemresolution: 3.4 Åin vitro · ligands ADP, BEF, MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7O73-9
RCSB PDB
cryoemresolution: 3.4 Åin vitro · ligands ADP, BEF, MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7O75-9
RCSB PDB
cryoemresolution: 3.2 Åin vitro · ligands ADP, BEF, MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7RIM-4
RCSB PDB
xrayresolution: 2.9 Åin vitro · -173.15 °C · pH 6.5 · ligands 5N0, MG, ZN
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7RIP-4
RCSB PDB
xrayresolution: 3.3 Åin vitro · -173.15 °C · ligands 5N0, MG, PPV, ZN
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 soaked with CTP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7RIQ-3
RCSB PDB
xrayresolution: 3 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
RNA polymerase II elongation complex scaffold 1 without polyamide · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7RIW-3
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
RNA polymerase II elongation complex scaffold 2, without polyamide · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7RIX-4
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 6.5 · ligands 5N0, MG, ZN
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7RIY-4
RCSB PDB
xrayresolution: 3.7 Åin vitro · -173.15 °C · pH 6.5 · ligands 5N0, MG, ZN
RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2 soaked with UTP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7UI9-22
RCSB PDB
cryoemresolution: 3.3 Åin vitro
Core Mediator-PICearly (Copy A) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7UI9-21
RCSB PDB
cryoemresolution: 3.3 Åin vitro
Core Mediator-PICearly (Copy A) · DNA-directed RNA polymerase II subunit RPB1 (chains z)
unmapped
EV-PDB-7UIF-1
RCSB PDB
cryoemresolution: 4.6 Åin vitro
Mediator-PIC Early (Core B) · DNA-directed RNA polymerase II subunit RPB1 (chains A,z)
unmapped
EV-PDB-7UIG-17
RCSB PDB
cryoemresolution: 4.3 Åin vitro
Mediator-PIC Early (Mediator A) · DNA-directed RNA polymerase II subunit RPB1 (chains z)
unmapped
EV-PDB-7UIO-23
RCSB PDB
cryoemresolution: 3.3 Åin vitro · ligands ALA, ASP, THR, ZN
Mediator-PIC Early (Composite Model) · DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA)
unmapped
EV-PDB-7UIO-22
RCSB PDB
cryoemresolution: 3.3 Åin vitro · ligands ALA, ASP, THR, ZN
Mediator-PIC Early (Composite Model) · DNA-directed RNA polymerase II subunit RPB1 (chains Az,Bz)
unmapped
EV-PDB-7ZSB-1
RCSB PDB
cryoemresolution: 6.6 Åin vitro · ligands MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8CEN-9
RCSB PDB
cryoemresolution: 3 Åin vitro · ligands MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8CEO-9
RCSB PDB
cryoemresolution: 3.6 Åin vitro · ligands MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8JCH-1
RCSB PDB
cryoemresolution: 2.7 Åin vitro · ligands MG, ZN
Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 1 (Pol II Rat1-PTTC1) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8TVP-1
RCSB PDB
cryoemresolution: 3.7 Åin vitro · ligands MG, ZN
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8TVS-1
RCSB PDB
cryoemresolution: 4.4 Åin vitro · ligands MG, ZN
Cryo-EM structure of backtracked Pol II in complex with Rad26 · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-8TVV-1
RCSB PDB
cryoemresolution: 3.7 Åin vitro · ligands MG, ZN
Cryo-EM structure of backtracked Pol II · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8TVQ-1
RCSB PDB
cryoemresolution: 4.6 Åin vitro · ligands MG, ZN
Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8TUG-1
RCSB PDB
cryoemresolution: 3.5 Åin vitro · ligands MG, ZN
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8RAP-1
RCSB PDB
cryoemresolution: 4.3 Åin vitro · ligands ADP, BEF, MG, ZN
Structure of Sen1-ADP.BeF3 bound RNA Polymerase II pre-termination complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8RAM-1
RCSB PDB
cryoemresolution: 2.8 Åin vitro · ligands MG, ZN
Structure of Sen1 bound RNA Polymerase II pre-termination complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8K5P-1
RCSB PDB
cryoemresolution: 2.8 Åin vitro · ligands MG, ZN
Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 2 (Pol II Rat1-PTTC2) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7ZSA-1
RCSB PDB
cryoemresolution: 4 Åin vitro · ligands MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7ZS9-1
RCSB PDB
cryoemresolution: 3.1 Åin vitro · ligands MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-7O4J-9
RCSB PDB
cryoemresolution: 2.9 Åin vitro · ligands ADP, BEF, MG, SF4, ZN
Yeast RNA polymerase II transcription pre-initiation complex (consensus) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6UQ2-4
RCSB PDB
xrayresolution: 3.2 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
RNA polymerase II elongation complex with dG in state 1 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6UPY-4
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 6.5 · ligands APC, MG, ZN
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-6UPX-4
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · pH 6.5 · ligands MG, ZN
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9N5D-4
RCSB PDB
xrayresolution: 3.35 Åin vitro · -173.15 °C · ligands MG, PPV, ZN
RNA polymerase II elongation complex with 8-oxoG at +1 site, CMP added · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PDR-11
RCSB PDB
cryoemresolution: 2.84 Åin vitro · ligands MG, SF4, ZN
Composite map of PIC-Med-SWI/SNF-Nucleosome · DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)
unmapped
EV-PDB-9SB4-1
RCSB PDB
cryoemresolution: 3.12 Åin vitro · ligands MG, PPV, ZN
Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-D · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SB3-1
RCSB PDB
cryoemresolution: 3.05 Åin vitro · ligands MG, PPV, ZN
Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-C · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SB2-1
RCSB PDB
cryoemresolution: 3.09 Åin vitro · ligands MG, PPV, ZN
Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-B · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SB1-1
RCSB PDB
cryoemresolution: 2.98 Åin vitro · ligands MG, PPV, ZN
Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-A · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SB0-1
RCSB PDB
cryoemresolution: 3.04 Åin vitro · ligands MG, PPV, ZN
Structure of Yeast RNA polymerase II elongation complex with NTP-state-VI · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SAZ-1
RCSB PDB
cryoemresolution: 3.31 Åin vitro · ligands MG, ZN
Structure of Yeast RNA polymerase II elongation complex apo-state-II · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SAY-1
RCSB PDB
cryoemresolution: 3.44 Åin vitro · ligands MG, ZN
Structure of Yeast RNA polymerase II elongation complex apo-state-I · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9RYB-1
RCSB PDB
cryoemresolution: 2.33 Åin vitro · ligands DPO, K, MG, ZN
CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis state · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9QEB-1
RCSB PDB
cryoemresolution: 2.26 Åin vitro · ligands ATP, K, MG, ZN
CryoEM structure of transcribing RNA polymerase II elongation complex · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PVX-4
RCSB PDB
xrayresolution: 3.39 Åin vitro · -173.15 °C · ligands 8GT, MG, ZN
RNA polymerase II elongation complex with dA at +1 site, 8-oxo-GTP bound in E-site. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PVW-4
RCSB PDB
xrayresolution: 3.56 Åin vitro · -173.15 °C · ligands MG, POP, ZN
RNA polymerase II elongation complex with dA at +1 site, 8-oxo-GMP added in Syn-conformation · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PVV-4
RCSB PDB
xrayresolution: 3.48 Åin vitro · -173.15 °C · ligands 8GT, MG, ZN
RNA polymerase II elongation complex with dC at +1 site, 8-oxo-GTP bound in A-site. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PVU-4
RCSB PDB
xrayresolution: 3.31 Åin vitro · -173.15 °C · ligands MG, ZN
RNA polymerase II elongation complex with dC at +1 site, 8-oxo-GMP added. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PDK-11
RCSB PDB
cryoemresolution: 2.8 Åin vitro · ligands MG, SF4, ZN
Composite map of closed form of PIC-Med-SWI/SNF · DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)
unmapped
EV-PDB-9PDJ-11
RCSB PDB
cryoemresolution: 2.8 Åin vitro · ligands MG, SF4, ZN
Composite map of open form of PIC-Med-SWI/SNF · DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)
unmapped
EV-PDB-9PC8-7
RCSB PDB
cryoemresolution: 3.4 Åin vitro
Core Mediator of PIC-Med-SWI/SNF · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PC7-15
RCSB PDB
cryoemresolution: 3.4 Åin vitro
Core Mediator of PIC-Med-SWI/SNF-Nucleosome · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PBZ-12
RCSB PDB
cryoemresolution: 3.6 Åin vitro · ligands MG, ZN
PolII/TFIIF of PIC-Med-SWI/SNF-Nucleosome · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9PBD-11
RCSB PDB
cryoemresolution: 2.9 Åin vitro · ligands MG, ZN
PolII/TFIIF of PIC-Med-SWI/SNF · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9N5G-4
RCSB PDB
xrayresolution: 3.15 Åin vitro · -173.15 °C · ligands ATP, MG, ZN
RNA polymerase II elongation complex with 8-oxoG at +1 site, ATP in both A- and E-site · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9N5F-4
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · ligands MG, ZN
RNA polymerase II elongation complex with 8-oxoG in syn-conformation with added AMP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9N5E-4
RCSB PDB
xrayresolution: 3.75 Åin vitro · -173.15 °C · ligands APC, MG, ZN
RNA polymerase II elongation complex with 8-oxoG at +1 site, AMPCPP in E-site · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9N5C-4
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · ligands 2TM, MG, ZN
RNA polymerase II elongation complex with 8-oxoG at +1 site, CMPCPP-bound · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9N5B-4
RCSB PDB
xrayresolution: 3.1 Åin vitro · -173.15 °C · ligands MG, ZN
RNA polymerase II elongation complex containing 8-oxoG at +1 site, apo form · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9KDQ-1
RCSB PDB
cryoemresolution: 2.63 Åin vitro · ligands MG, ZN
The structure of 3 ACTD bound to RNA polymerase II elongation complex with 4 CTG repeats. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9KDO-1
RCSB PDB
cryoemresolution: 2.92 Åin vitro · ligands MG, ZN
The structure of 2 ACTD bound to RNA polymerase II elongation complex with 3 CTG repeats · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9KDN-1
RCSB PDB
cryoemresolution: 2.96 Åin vitro · ligands MG, ZN
The structure of 1 ACTD bound to RNA polymerase II elongation complex with 2 CTG repeats. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9KD9-1
RCSB PDB
cryoemresolution: 2.88 Åin vitro · ligands MG, ZN
The structure of RNA polymerase II elongation complex paused at N-5 state by actinomycin D. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9KD8-1
RCSB PDB
cryoemresolution: 2.46 Åin vitro · ligands MG, ZN
The structure of RNA polymerase II elongation complex paused at N-2 state by actinomycin D. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9KD7-1
RCSB PDB
cryoemresolution: 3.09 Åin vitro · ligands MG, ZN
The structure of RNA polymerase II elongation complex paused at N-1 state by actinomycin D. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9K7F-1
RCSB PDB
cryoemresolution: 2.5 Åin vitro · ligands MG, ZN
RNA polymerase II elongation complex apo structure. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9JA1-1
RCSB PDB
cryoemresolution: 2.98 Åin vitro · ligands ATP, MG, ZN
The RNA polymerase II elongation complex from Saccharomyces cerevisiae · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9BW0-1
RCSB PDB
xrayresolution: 3.51 Åin vitro · -173.15 °C · pH 7 · ligands ZN
RNA Polymerase II - No ATP · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9BVT-1
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · ligands GOL, MN, ZN
RNA Pol II - High Mn(+2) concentration · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8UOT-8
RCSB PDB
cryoemresolution: 3.7 Åin vitro · ligands MG, SF4, ZN
Composite map of PICdeltaTFIIK form1 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8UOQ-2
RCSB PDB
cryoemresolution: 3.8 Åin vitro · ligands MG, SF4, ZN
Composite map of PIC_delta_TFIIK form2 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8UMI-8
RCSB PDB
cryoemresolution: 3.7 Åin vitro · ligands MG, SF4, ZN
consensus map of PICdeltaTFIIK form1 · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-8UMH-2
RCSB PDB
cryoemresolution: 4.1 Åin vitro · ligands MG, SF4, ZN
Consensus map of PICdeltaTFIIK form2 · DNA-directed RNA polymerase subunit (chains A)
unmapped
EV-PDB-8UKU-4
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · ligands MG, POP, ZN
RNA polymerase II elongation complex with Fapy-dG lesion with CMP added · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8UKT-4
RCSB PDB
xrayresolution: 3.6 Åin vitro · -173.15 °C · ligands MG, POP, ZN
RNA polymerase II elongation complex with Fapy-dG lesion with AMP added · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8UKS-4
RCSB PDB
xrayresolution: 3.4 Åin vitro · -173.15 °C · ligands CTP, MG, ZN
RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8UKR-4
RCSB PDB
xrayresolution: 3.78 Åin vitro · -173.15 °C · ligands ATP, MG, ZN
RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8UKQ-4
RCSB PDB
xrayresolution: 3.5 Åin vitro · -173.15 °C · ligands MG, ZN
RNA polymerase II elongation complex with Fapy-dG lesion in apo state · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8U9X-1
RCSB PDB
xrayresolution: 3.05 Åin vitro · -173.15 °C · pH 7.5 · ligands ATP, GOL, MN, ZN
STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8U9R-1
RCSB PDB
xrayresolution: 3.34 Åin vitro · -173.15 °C · ligands ATP, GOL, MG, ZN
STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8TVY-1
RCSB PDB
cryoemresolution: 3.1 Åin vitro · ligands MG, ZN
Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8TVX-1
RCSB PDB
cryoemresolution: 3.7 Åin vitro · ligands MG, ZN
Cryo-EM structure of CPD-stalled Pol II (Conformation 2) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-8TVW-1
RCSB PDB
cryoemresolution: 3.6 Åin vitro · ligands MG, ZN
Cryo-EM structure of CPD-stalled Pol II (conformation 1) · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SB5-1
RCSB PDB
cryoemresolution: 3.56 Åin vitro · ligands MG, ZN
Structure of Yeast RNA polymerase II elongation complex with NTP-state-II · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBL-1
RCSB PDB
cryoemresolution: 4.28 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-1 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBM-1
RCSB PDB
cryoemresolution: 4.17 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-2 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBP-1
RCSB PDB
cryoemresolution: 3.95 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-5 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBQ-1
RCSB PDB
cryoemresolution: 3.88 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-6 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBR-1
RCSB PDB
cryoemresolution: 3.96 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-7 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBS-1
RCSB PDB
cryoemresolution: 3.85 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-8 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBT-1
RCSB PDB
cryoemresolution: 3.85 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-9 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBU-1
RCSB PDB
cryoemresolution: 3.83 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-10 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBW-1
RCSB PDB
cryoemresolution: 3.63 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-12 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBX-1
RCSB PDB
cryoemresolution: 3.53 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-13 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBY-1
RCSB PDB
cryoemresolution: 3.41 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-14 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBZ-1
RCSB PDB
cryoemresolution: 3.35 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-15 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SC1-1
RCSB PDB
cryoemresolution: 3.48 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-17 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SC4-1
RCSB PDB
cryoemresolution: 3.76 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-20 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8R-12
RCSB PDB
cryoemresolution: 2.68 Åin vitro · ligands MG, ZN
Structure of yeast Pol II in complex with a short control scaffold lacking cisplatin-ICL lesion. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8T-1
RCSB PDB
cryoemresolution: 2.56 Åin vitro · ligands CPT, MG, ZN
Structure of yeast Pol II in complex with a cisplatin-induced inter-strand crosslink lesion at the +7 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8U-1
RCSB PDB
cryoemresolution: 2.61 Åin vitro · ligands CPT, MG, ZN
Structure of pre-translocation state of yeast Pol II complexed with a cisplatin-induced inter-strand crosslink at the +2 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8V-1
RCSB PDB
cryoemresolution: 2.23 Åin vitro · ligands CPT, MG, ZN
Structure of post-translocation state of yeast Pol II complexed with a cisplatin-induced inter-strand crosslink at the +2 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8Y-1
RCSB PDB
cryoemresolution: 3.08 Åin vitro · ligands CPT, MG, ZN
Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink at the + 3 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8Z-1
RCSB PDB
cryoemresolution: 3.03 Åin vitro · ligands CPT, MG, ZN
Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink at the + 2 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9WQ7-1
RCSB PDB
cryoemresolution: 2.72 Åin vitro · ligands CPT, MG, ZN
Structure of yeast Pol II-Elf1 complex containing a cisplatin-ICL lesion at +7 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9WQ8-1
RCSB PDB
cryoemresolution: 2.98 Åin vitro · ligands CPT, MG, ZN
Structure of yeast Pol II in complex with a longer scaffold containing a cisplatin-ICL lesion at +7 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9WQ9-1
RCSB PDB
cryoemresolution: 2.95 Åin vitro · ligands MG, ZN
Structure of yeast Pol II in complex with a longer control scaffold lacking cisplatin-ICL lesion. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9ZPL-9
RCSB PDB
cryoemresolution: 3.75 Åin vitro · ligands ZN
Cryo-EM structure of the complete Saccharomyces cerevisiae RNA polymerase II in open clamp conformation · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9ZPK-1
RCSB PDB
cryoemresolution: 3.31 Åin vitro · ligands ZN
Cryo-EM structure of the complete Saccharomyces cerevisiae RNA polymerase II in closed clamp conformation · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8X-1
RCSB PDB
cryoemresolution: 2.86 Åin vitro · ligands CPT, MG, ZN
Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink lesion at the +5 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9W8W-12
RCSB PDB
cryoemresolution: 2.91 Åin vitro · ligands CPT, MG, ZN
Structure of backtracked yeast Pol II in complex with a cisplatin-induced inter-strand crosslink lesion at the +2 position. · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SV6-1
RCSB PDB
cryoemresolution: 1.96 Åin vitro · ligands ATP, K, MG, ZN
CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SC3-1
RCSB PDB
cryoemresolution: 3.68 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-19 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SC2-1
RCSB PDB
cryoemresolution: 3.53 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-18 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SC0-1
RCSB PDB
cryoemresolution: 3.31 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-16 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBV-1
RCSB PDB
cryoemresolution: 3.73 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-11 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBO-1
RCSB PDB
cryoemresolution: 3.97 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-4 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-PDB-9SBN-1
RCSB PDB
cryoemresolution: 3.95 Åin vitro · ligands ATP, MG, ZN
Structure of Yeast RNA polymerase II elongation complex with ATP frame-3 · DNA-directed RNA polymerase II subunit RPB1 (chains A)
unmapped
EV-BMRB-17044
BMRB
nmr_shiftschemical_shiftin vitro · 24.85 °C · pH 7.4
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts
unmapped
EV-BMRB-34041
BMRB
nmr_shiftschemical_shiftin vitro · 19.85 °C · pH 6.8
Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts
unmapped
EV-BMRB-34058
BMRB
nmr_shiftschemical_shiftin vitro · 24.85 °C · pH 6.8
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts
unmapped
EV-SASBDB-SASDCZ2
SASBDB
saxs_sansradius_of_gyration: 5.294 nm ± 0.02in vitro · 4 °C · pH 6.5 · ligands partner: Regulator of Ty1 transposition protein 103
Structure and dynamics of the RNAPII CTDsome with Rtt103. · DNA-directed RNA polymerase II subunit RPB1 with Regulator of Ty1 transposition protein 103
unmapped
EV-DISPROT-DP02527r003
DisProt
gel_electrophoresisdisorder_region: 168 residuesin vitro
DisProt DP02527: disorder, residues 1549-1716 · residues 1549-1716; evidence: sodium dodecyl sulfate polyacrylamide gel electrophoresis evidence used in manual assertion
unmapped
EV-DISPROT-DP02527r004
DisProt
xraydisorder_region: 278 residuesin vitro
DisProt DP02527: disorder, residues 1456-1733 · residues 1456-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion
unmapped
EV-DISPROT-DP02527r005
DisProt
xraydisorder_region: 288 residuesin vitro
DisProt DP02527: disorder, residues 1446-1733 · residues 1446-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion
unmapped
EV-DISPROT-DP02527r006
DisProt
xraydisorder_region: 288 residuesin vitro
DisProt DP02527: disorder, residues 1446-1733 · residues 1446-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion
unmapped
EV-DISPROT-DP02527r007
DisProt
xraydisorder_region: 279 residuesin vitro
DisProt DP02527: disorder, residues 1455-1733 · residues 1455-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion
unmapped
EV-AFDB-AF-P04050-F1
AlphaFold DB
af_predictionplddt: 81.38 pLDDTin silico
AlphaFold DB prediction AF-P04050-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-1733
unmapped
EV-SMASH-SMFS-000154
SMASH-BIO
force_spectroscopystudy_recordin vitro · pH 7.5
Kinetic control of mammalian transcription elongation. · RNA polymerase II; optical tweezers; experiment class: translation_transcription_replication
unmapped
EV-SMASH-SMFS-000445
SMASH-BIO
force_spectroscopystudy_recordin vitro
FACT weakens the nucleosomal barrier to transcription and preserves its integrity by forming a hexasome-like intermediate. · RNA polymerase II; optical tweezers; experiment class: chromatin_mechanics, nucleic_acid_protein_interaction, translation_transcription_replication
unmapped
EV-SMASH-SMFS-001789
SMASH-BIO
force_spectroscopystudy_recordin vitro · pH 7.5
Visualizing carboxyl-terminal domain of RNA polymerase II recruitment by FET fusion protein condensates with DNA curtains. · RNA polymerase II; hydrodynamic stretching; experiment class: translation_transcription_replication
unmapped
EV-SMASH-SMFS-002138
SMASH-BIO
force_spectroscopystudy_recordin vitro
Single-molecule Imaging of EWS-FLI1 Condensates Assembling on DNA. · RNA polymerase II; hydrodynamic stretching; experiment class: force_generation_motor, nucleic_acid_protein_interaction, translation_transcription_replication
unmapped
EV-SMASH-SMFS-002673
SMASH-BIO
force_spectroscopystudy_recordin vitro
DNA origami-based single-molecule force spectroscopy unravels the molecular basis of RNA Polymerase III pre-initiation complex stability · RNA polymerase II; afm smfs; experiment class: nucleic_acid_protein_interaction, translation_transcription_replication
unmapped
EV-SMASH-SMFS-003625
SMASH-BIO
force_spectroscopystudy_recordin vitro · pH 8
Observing Single RNA Polymerase Molecules Down to Base-Pair Resolution. · RNA polymerase II; optical tweezers; experiment class: force_generation_motor, translation_transcription_replication
unmapped
EV-SMASH-SMFS-003748
SMASH-BIO
force_spectroscopystudy_recordin vitro · pH 7.6
TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning. · RNA polymerase II; magnetic tweezers; experiment class: force_generation_motor, nucleic_acid_protein_interaction, translation_transcription_replication
unmapped
EV-SMASH-SMFS-003802
SMASH-BIO
force_spectroscopystudy_recordin vitro
A Novel Initiation Pathway in Escherichia Coli Transcription · RNA polymerase II; magnetic tweezers; experiment class: translation_transcription_replication
unmapped
EV-SMASH-SMFS-003828
SMASH-BIO
force_spectroscopystudy_recordin vitro
Backtracked and paused transcription initiation intermediate of Escherichia coli RNA polymerase. · RNA polymerase II; magnetic tweezers; experiment class: translation_transcription_replication
unmapped
EV-SMASH-SMFS-003889
SMASH-BIO
force_spectroscopystudy_recordin vitro
Elucidation of the Dynamics of Transcription Elongation by RNA Polymerase II using Kinetic Network Models. · RNA polymerase II; optical tweezers; experiment class: force_generation_motor, nucleic_acid_protein_interaction, translation_transcription_replication
unmapped
EV-SMASH-SMFS-003957
SMASH-BIO
force_spectroscopystudy_recordin vitro
Mechanisms of backtrack recovery by RNA polymerases I and II. · RNA polymerase II; optical tweezers; experiment class: translation_transcription_replication
unmapped
EV-SMASH-SMFS-003990
SMASH-BIO
force_spectroscopystudy_recordin vitro
Nucleosomal arrangement affects single-molecule transcription dynamics. · RNA polymerase II; optical tweezers; experiment class: chromatin_mechanics, nucleic_acid_protein_interaction, translation_transcription_replication
unmapped
EV-SMASH-SMFS-004743
SMASH-BIO
force_spectroscopystudy_recordin vitro
Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms. · RNA polymerase II; optical tweezers; experiment class: translation_transcription_replication
unmapped
EV-SMASH-SMFS-005179
SMASH-BIO
force_spectroscopystudy_recordin vitro
Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II. · RNA polymerase II; optical tweezers; experiment class: translation_transcription_replication
unmapped
EV-SMASH-SMFS-005381
SMASH-BIO
force_spectroscopystudy_recordin vitro
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II. · RNA polymerase II; optical tweezers; experiment class: force_generation_motor, translation_transcription_replication
unmapped
EV-SMASH-SMFS-006189
SMASH-BIO
force_spectroscopystudy_recordin vitro · pH 8
Single molecule transcription elongation. · RNA polymerase II; optical tweezers; experiment class: chromatin_mechanics, force_generation_motor, translation_transcription_replication
unmapped
EV-SMASH-SMFS-006463
SMASH-BIO
force_spectroscopystudy_recordin vitro
Single-molecule studies of RNA polymerase: motoring along. · RNA polymerase II; optical tweezers; experiment class: force_generation_motor, translation_transcription_replication
unmapped
EV-SMASH-SMFS-006535
SMASH-BIO
force_spectroscopystudy_recordin vitro
Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner. · RNA polymerase II; optical tweezers; experiment class: rheology_cell, translation_transcription_replication
unmapped

Conflicts

No conflicts found among comparable evidence.

315 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.

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