Fibronectin
UniProt P02751 · gene FN1 · Homo sapiens · 2477 residues
216evidence items
0mapped to a state
0states
8techniques
5sources
0conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | nmr_structure | nmr_shifts | force_spectroscopy | integrative | af_prediction | md | Total |
|---|---|---|---|---|---|---|---|---|---|---|
| No states defined yet. | ||||||||||
Unmapped evidence: 216 of 216 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 5 | 0 |
| MDDB | 1 | 0 |
| RCSB PDB | 71 | 0 |
| SMASH-BIO | 138 | 0 |
Structure
No state models are exported for this protein yet. Observed states export the representative PDB entry; inferred states need fitted models, not yet built.
States and transitions
No states defined.
| State | Basis | Parent | Description |
|---|
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-1E88-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 4.5 · ligands NAG Solution structure of 6F11F22F2, a compact three-module fragment of the gelatin-binding domain of human fibronectin · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-1E8B-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 4.5 · ligands NAG Solution structure of 6F11F22F2, a compact three-module fragment of the gelatin-binding domain of human fibronectin · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-1FNA-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro CRYSTAL STRUCTURE OF THE TENTH TYPE III CELL ADHESION MODULE OF HUMAN FIBRONECTIN · FIBRONECTIN CELL-ADHESION MODULE TYPE III-10 (chains A) | unmapped |
| EV-PDB-1FNF-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 5.8 FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10 · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-1OWW-1 RCSB PDB | nmr_structure | structure | in vitro · 39.85 °C · pH 6 Solution structure of the first type III module of human fibronectin determined by 1H, 15N NMR spectroscopy · Fibronectin first type III module (chains A) | unmapped |
| EV-PDB-1Q38-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7 Anastellin · Fibronectin (chains A) | unmapped |
| EV-PDB-1QO6-1 RCSB PDB | nmr_structure | structure | in vitro · 36.85 °C · pH 4.5 Solution structure of a pair of modules from the gelatin-binding domain of fibronectin · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-1TTF-1 RCSB PDB | nmr_structure | structure | in vitro THE THREE-DIMENSIONAL STRUCTURE OF THE TENTH TYPE III MODULE OF FIBRONECTIN: AN INSIGHT INTO RGD-MEDIATED INTERACTIONS · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-1TTG-1 RCSB PDB | nmr_structure | structure | in vitro THE THREE-DIMENSIONAL STRUCTURE OF THE TENTH TYPE III MODULE OF FIBRONECTIN: AN INSIGHT INTO RGD-MEDIATED INTERACTIONS · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-2CG6-1 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · pH 4.5 · ligands SO4 Second and third fibronectin type I module pair (crystal form I). · HUMAN FIBRONECTIN (chains A) | unmapped |
| EV-PDB-2CG7-1 RCSB PDB | xray | resolution: 1.2 Å | in vitro · -173.15 °C · pH 7 SECOND AND THIRD FIBRONECTIN TYPE I MODULE PAIR (CRYSTAL FORM II). · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-2CK2-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 5.1 · ligands ACE Structure of core-swapped mutant of fibronectin · HUMAN FIBRONECTIN (chains A,B) | unmapped |
| EV-PDB-2CKU-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C Solution structure of 2F13F1 from human fibronectin · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-2EC3-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7 Solution structure of the 11th FN1 domain from human Fibronectin 1 · Fibronectin (chains A) | unmapped |
| EV-PDB-2FN2-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 4.5 · ligands NAG SOLUTION NMR STRUCTURE OF THE GLYCOSYLATED SECOND TYPE TWO MODULE OF FIBRONECTIN, 20 STRUCTURES · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-2FNB-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7 NMR STRUCTURE OF THE FIBRONECTIN ED-B DOMAIN, NMR, 20 STRUCTURES · PROTEIN (FIBRONECTIN) (chains A) | unmapped |
| EV-PDB-2GEE-1 RCSB PDB | xray | resolution: 2.01 Å | in vitro · -73.15 °C · pH 8 Crystal Structure of Human Type III Fibronectin Extradomain B and Domain 8 · hypothetical protein (chains A) | unmapped |
| EV-PDB-2H41-1 RCSB PDB | nmr_structure | structure | in vitro · 29.85 °C · pH 7 Solution structure of the second type III domain of human Fibronectin: minimized average structure · Fibronectin (chains A) | unmapped |
| EV-PDB-2H45-1 RCSB PDB | nmr_structure | structure | in vitro · 29.85 °C · pH 7 Solution structure of the second type III domain of human Fibronectin: ensemble of 25 structures · Fibronectin (chains A) | unmapped |
| EV-PDB-2HA1-1 RCSB PDB | nmr_structure | structure | in vitro · 29.85 °C · pH 7 Complex of the first and second type III domains of human Fibronectin in solution · Fibronectin (chains A) | unmapped |
| EV-PDB-2MNU-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6 Backbone and side chain 1H, 13C, and 15N Chemical Shift Assignments for EDB and specific binding aptide · EDB (chains A) | unmapped |
| EV-PDB-2N1K-1 RCSB PDB | nmr_structure | structure | in vitro · 25 °C · pH 7.5 Structure of the Third Type III Domain from Human Fibronectin · Fibronectin (chains A) | unmapped |
| EV-PDB-2RL0-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 6.2 Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 · Fibronectin (chains A,B,D,F,I,K) | unmapped |
| EV-PDB-30UC-2 RCSB PDB | cryoem | resolution: 2.8 Å | in vitro · ligands GDP, NAG Complex of transglutaminase 2 and the 45 kDa domain of fibronectin · Fibronectin (chains B) | unmapped |
| EV-PDB-3CAL-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 7 Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-5 · Fibronectin (chains A,C) | unmapped |
| EV-PDB-3EJH-1 RCSB PDB | xray | resolution: 2.1 Å | in vitro · -173.15 °C · pH 6.5 · ligands GOL, NAG Crystal Structure of the Fibronectin 8-9FnI Domain Pair in Complex with a Type-I Collagen Peptide · Fibronectin (chains A,B) | unmapped |
| EV-PDB-3M7P-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · pH 6.5 · ligands 12P, NAG, ZN Fibronectin fragment · FN1 protein (chains A) | unmapped |
| EV-PDB-3MQL-1 RCSB PDB | xray | resolution: 3.004 Å | in vitro · -173.15 °C · pH 7 · ligands MPD, MRD, NAG Crystal structure of the fibronectin 6FnI1-2FnII7FnI fragment · Fibronectin 1 (chains A) | unmapped |
| EV-PDB-3R8Q-1 RCSB PDB | xray | resolution: 2.4 Å | in vitro · -173.15 °C · pH 7.5 Structure of Fibronectin domain 12-14 · Fibronectin (chains A) | unmapped |
| EV-PDB-3T1W-1 RCSB PDB | xray | resolution: 2.4 Å | in vitro · -173.15 °C · pH 9 Structure of the four-domain fragment Fn7B89 of oncofetal fibronectin · four-domain fibronectin fragment (chains A) | unmapped |
| EV-PDB-4JE4-2 RCSB PDB | xray | resolution: 2.31 Å | in vitro · -173.15 °C · pH 8 Crystal Structure of Monobody NSa1/SHP2 N-SH2 Domain Complex · Monobody NSa1 (chains B) | unmapped |
| EV-PDB-4JEG-2 RCSB PDB | xray | resolution: 2.3 Å | in vitro · -173.15 °C · pH 6.5 Crystal Structure of Monobody CS1/SHP2 C-SH2 Domain Complex · Monobody CS1 (chains B) | unmapped |
| EV-PDB-4LXO-1 RCSB PDB | xray | resolution: 1.42 Å | in vitro · -173.15 °C · pH 7.6 · ligands CA Crystal structure of 9,10Fn3-elegantin chimera · Fibronectin (chains A,B) | unmapped |
| EV-PDB-4MMX-3 RCSB PDB | xray | resolution: 3.32 Å | in vitro · -173.15 °C · pH 4.5 · ligands MN, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin · Fibronectin (chains C) | unmapped |
| EV-PDB-4MMY-3 RCSB PDB | xray | resolution: 3.183 Å | in vitro · -173.15 °C · pH 4.5 · ligands MN, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif · Fibronectin (chains C) | unmapped |
| EV-PDB-4MMZ-3 RCSB PDB | xray | resolution: 3.1 Å | in vitro · -173.15 °C · pH 4.5 · ligands GOL, MN, NA, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Integrin AlphaVBeta3 ectodomain bound to an antagonistic tenth domain of Fibronectin · Fibronectin (chains C) | unmapped |
| EV-PDB-4PZ5-1 RCSB PDB | xray | resolution: 1.96 Å | in vitro · -173.15 °C · pH 6.9 Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of BBK32 from Borrelia burgdorferi · Fibronectin (chains A) | unmapped |
| EV-PDB-5DC0-1 RCSB PDB | xray | resolution: 2.23 Å | in vitro · -173.15 °C · pH 8 CRYSTAL STRUCTURE OF MONOBODY GG3/ABL1 SH2 DOMAIN COMPLEX · Fibronectin (chains A) | unmapped |
| EV-PDB-5DC4-2 RCSB PDB | xray | resolution: 1.48 Å | in vitro · -173.15 °C · pH 7.83 · ligands GOL CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL A · AS25 monobody (chains B) | unmapped |
| EV-PDB-4GH7-2 RCSB PDB | xray | resolution: 2.6 Å | in vitro · -173.15 °C Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8 · Fibronectin (chains B,D) | unmapped |
| EV-PDB-3ZRZ-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 7 · ligands GOL, SO4 Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of Streptococcus pyogenes SfbI-5 · FIBRONECTIN (chains A,B) | unmapped |
| EV-PDB-3GXE-1 RCSB PDB | xray | resolution: 2.6 Å | in vitro · -173.15 °C · pH 7.5 · ligands GOL, NAG Complex of a Low Affinity Collagen Site with the Fibronectin 8-9FnI Domain Pair · Fibronectin (chains A,B) | unmapped |
| EV-PDB-2RKZ-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 7 · ligands SIN Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 · Fibronectin (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-2RKY-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173.15 °C · pH 8.5 · ligands K, SCN Crystal structure of the fourth and fifth fibronectin F1 modules in complex with a fragment of staphylococcus aureus fnbpa-1 · Fibronectin (chains A,C) | unmapped |
| EV-PDB-2OCF-2 RCSB PDB | xray | resolution: 2.95 Å | in vitro · -173.15 °C · pH 8 · ligands EST Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody · Fibronectin (chains D) | unmapped |
| EV-PDB-1QGB-1 RCSB PDB | nmr_structure | structure | in vitro · 36.85 °C · pH 4 SOLUTION STRUCTURE OF THE N-TERMINAL F1 MODULE PAIR FROM HUMAN FIBRONECTIN · PROTEIN (FIBRONECTIN) (chains A) | unmapped |
| EV-PDB-1O9A-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 5 Solution structure of the complex of 1F12F1 from fibronectin with B3 from FnBB from S. dysgalactiae · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-1J8K-1 RCSB PDB | nmr_structure | structure | in vitro · 19.85 °C · pH 7 NMR STRUCTURE OF THE FIBRONECTIN EDA DOMAIN, NMR, 20 STRUCTURES · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-1FNH-1 RCSB PDB | xray | resolution: 2.8 Å | in vitro · -173.15 °C · pH 7.5 CRYSTAL STRUCTURE OF HEPARIN AND INTEGRIN BINDING SEGMENT OF HUMAN FIBRONECTIN · PROTEIN (FIBRONECTIN) (chains A) | unmapped |
| EV-PDB-1FBR-1 RCSB PDB | nmr_structure | structure | in vitro FOURTH AND FIFTH FIBRONECTIN TYPE I MODULE PAIR · FIBRONECTIN (chains A) | unmapped |
| EV-PDB-5DC9-2 RCSB PDB | xray | resolution: 1.56 Å | in vitro · -173.15 °C · pH 8.5 · ligands GOL, IMD CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL B · AS25 monobody (chains B) | unmapped |
| EV-PDB-5DFT-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · ligands CIT Structure of the Eleventh Type III Domain from Human Fibronectin · Fibronectin (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-5J6Z-2 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7.5 Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin · Anastellin (chains B) | unmapped |
| EV-PDB-5J6Z-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7.5 Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin · Fibronectin (chains A) | unmapped |
| EV-PDB-5J7C-2 RCSB PDB | xray | resolution: 2.535 Å | in vitro · -173.15 °C · pH 8.8 A picomolar affinity FN3 domain in complex with hen egg-white lysozyme · FNfn10-anti-lysozyme (DE0.4.1) (chains C,D) | unmapped |
| EV-PDB-5M0A-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6.5 Solution structure of isolated 15th Fibronectin III domain from human fibronectin · Fibronectin (chains A) | unmapped |
| EV-PDB-5N47-2 RCSB PDB | xray | resolution: 3 Å | in vitro · -173.15 °C · pH 5.5 Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin · Fibronectin (chains B,D,F) | unmapped |
| EV-PDB-5N48-2 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 6.5 Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin · Fibronectin (chains B,D) | unmapped |
| EV-PDB-6MFA-1 RCSB PDB | xray | resolution: 1.754 Å | in vitro · -173.15 °C · pH 5.5 Fragment of human fibronectin containing the 4th-7th type III domains · Fibronectin (chains A) | unmapped |
| EV-PDB-6MSV-1 RCSB PDB | xray | resolution: 2.4 Å | in vitro · -173.15 °C · ligands GOL Structure of the 6th type III domain from human fibronectin · Fibronectin (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-6NAJ-3 RCSB PDB | xray | resolution: 3.1 Å | in vitro · -173.15 °C · pH 4.5 · ligands MN, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin. · Fibronectin, HR10 variant (chains C) | unmapped |
| EV-PDB-6XAY-1 RCSB PDB | xray | resolution: 2.48 Å | in vitro · -173.15 °C · ligands GOL Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains · Fibronectin (chains A,B,C,D) | unmapped |
| EV-PDB-7NWL-3 RCSB PDB | cryoem | resolution: 3.1 Å | in vitro · ligands MN, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp · Isoform 1 of Fibronectin (chains C) | unmapped |
| EV-PDB-8PEQ-1 RCSB PDB | xray | resolution: 2.32 Å | in vitro · -173.15 °C · pH 7.3 · ligands SO4 Complex of diubiquitin-derived artificial binding protein (Affilin) variant Af2 with its target oncofetal fibronectin (fragment 7B8) · Fibronectin (chains A,B,C) | unmapped |
| EV-PDB-9A3V-2 RCSB PDB | integrative | structure | in vitro Predicted model of tissue transglutaminase 2 (TG2) in complex with plasma fibronectin type III modules 14 and 15 (FNIII14-15) · Fibronectin (chains B) | unmapped |
| EV-PDB-9A3X-2 RCSB PDB | integrative | structure | in vitro Predicted model of tissue transglutaminase 2 (TG2) in complex with plasma fibronectin type I modules 2 and 3 (FNI2-3) · Fibronectin (chains B) | unmapped |
| EV-PDB-9A3Y-2 RCSB PDB | integrative | structure | in vitro Predicted model of tissue transglutaminase 2 (TG2) in complex with plasma fibronectin type I modules 7, 8 and 9 (FNI7-9) · Fibronectin (chains B) | unmapped |
| EV-PDB-9A3Z-2 RCSB PDB | integrative | structure | in vitro A predicted model of tissue transglutaminase 2 (TG2) in complex with plasma fibronectin's gelatin binding domain (FNI6FNII1-2FNI7-9). · Fibronectin (chains B) | unmapped |
| EV-PDB-9P6S-3 RCSB PDB | cryoem | resolution: 2.61 Å | in vitro · ligands MN, NAG, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Cryo-EM structure of human integrin alpha5beta1 in complex with fibronectin (FN 7-10) · Fibronectin (chains C) | unmapped |
| EV-PDB-6XAX-1 RCSB PDB | xray | resolution: 2.4 Å | in vitro · -173.15 °C · ligands GOL Structure of a fragment of human fibronectin containing the 11th type III domain, extra domain A, and the 12th type III domain · Fibronectin (chains A,B) | unmapped |
| EV-PDB-6HNF-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 7.4 Structure in solution of human fibronectin type III-domain 14 · Fibronectin (chains A) | unmapped |
| EV-BMRB-15986 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 7.2 Chemical Shift Assignments of the Fibronectin 8-9FnI Domain Pair in Complex with a Type-I Collagen Peptide · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-25564 BMRB | nmr_shifts | chemical_shift | in vitro · 25 °C · pH 7.5 Structure of the Third Type III Domain from Human Fibronectin · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-27610 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 7.4 Sequence-specific 1H, 13C, and 15N backbone assignment of Fibronectin type III 14 · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-30061 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 7.5 Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-34048 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.5 Solution structure of isolated 15th Fibronectin III domain from human fibronectin · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-AFDB-AF-P02751-F1 AlphaFold DB | af_prediction | plddt: 69.62 pLDDT | in silico AlphaFold DB prediction AF-P02751-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-2477 | unmapped |
| EV-MDDB-A00FZ MDDB | md | trajectory: 10 ns | in silico · 26.85 °C MoDEL 1FNA · start 1FNA; Amber Parm99 | unmapped |
| EV-SMASH-SMFS-000141 SMASH-BIO | force_spectroscopy | study_record | in vitro Interaction dynamics of borrelia surface proteins with fibronectin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000212 SMASH-BIO | force_spectroscopy | study_record | in vitro Nanoscale Mechanics of FnBPB-Mediated Adhesion of Staphylococcus aureus to Skin Ligands. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000224 SMASH-BIO | force_spectroscopy | study_record | in vitro Optical tweezers combined with FRET tension sensor reveal force-dependent vinculin dynamics. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000314 SMASH-BIO | force_spectroscopy | study_record | in vitro Surface tension-driven persistence: How hydrogel interfacial properties regulate fibroblast directional migration. · Fibronectin (FnIII domains); optical tweezers; experiment class: rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-000320 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 The Baraitser-Winter Cerebrofrontofacial Syndrome Recurrent R196H Variant in Cytoplasmic β-Actin Impairs Its Cellular Polymerization and Stability. · Fibronectin (FnIII domains); optical tweezers; experiment class: force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-000349 SMASH-BIO | force_spectroscopy | study_record | in vitro α5β1 and αvβ3 integrins employ two distinct adhesion strengthening modes to respond to fibronectin stiffness within seconds of initiating adhesion · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000455 SMASH-BIO | force_spectroscopy | study_record | in vitro Harnessing RGDS peptides to regulate bacterial-host interfaces for targeted antimicrobial therapy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-000473 SMASH-BIO | force_spectroscopy | study_record | in vitro Interaction of integrin αvβ3 and fibronectin under fluid shear forces: implications for tumor cell adhesion and migration. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000489 SMASH-BIO | force_spectroscopy | study_record | in vitro Load-dependent RGD-context sensing via αV-class integrin reprograms cellular adhesion and mechanics within seconds · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000551 SMASH-BIO | force_spectroscopy | study_record | in vitro Optical tweezers combined with FRET tension sensor reveal force-dependent vinculin dynamics · Fibronectin (FnIII domains); optical tweezers; experiment class: nucleic_acid_protein_interaction, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-000772 SMASH-BIO | force_spectroscopy | study_record | in vitro Folding and Misfolding Dynamics of Irisin Protein Revealed by Single-Molecule Magnetic Tweezers. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-000803 SMASH-BIO | force_spectroscopy | study_record | in vitro Integrin mechanosensing relies on a pivot-clip mechanism to reinforce cell adhesion. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001167 SMASH-BIO | force_spectroscopy | study_record | in vitro Free Energy Landscape of Type III Fibronectin Domain with Identified Intermediate State and Hierarchical Symmetry. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001198 SMASH-BIO | force_spectroscopy | study_record | in vitro Integrin Mechanosensing relies on Pivot-clip Mechanism to Reinforce Cell Adhesion · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-001250 SMASH-BIO | force_spectroscopy | study_record | in vitro Multiscale Computational Framework to Investigate Integrin Mechanosensing and Cell Adhesion · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001257 SMASH-BIO | force_spectroscopy | study_record | in vitro Native extracellular matrix probes to target patient- and tissue-specific cell-microenvironment interactions by force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001438 SMASH-BIO | force_spectroscopy | study_record | in vitro Cell mediated remodeling of stiffness matched collagen and fibrin scaffolds. · Fibronectin (FnIII domains); optical tweezers; experiment class: force_generation_polymerization, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-001440 SMASH-BIO | force_spectroscopy | study_record | in vitro Cell-Specific Response of NSIP- and IPF-Derived Fibroblasts to the Modification of the Elasticity, Biological Properties, and 3D Architecture of the Substrate. · Fibronectin (FnIII domains); afm smfs; experiment class: rheology_cell | unmapped |
| EV-SMASH-SMFS-001514 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 9.6 Fibronectin binding protein B binds to loricrin and promotes corneocyte adhesion by Staphylococcus aureus. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001638 SMASH-BIO | force_spectroscopy | study_record | in vitro Native extracellular matrix probes to target patient- and tissue- specific cell-microenvironment interactions by force spectroscopy · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-001735 SMASH-BIO | force_spectroscopy | study_record | in vitro Stiffness-Matched Extracellular Matrices Comprising Collagen or Fibrin Differentially Affect Cell-Mediated Remodeling and Peri-Cellular Stiffness · Fibronectin (FnIII domains); optical tweezers; experiment class: force_generation_polymerization, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-001778 SMASH-BIO | force_spectroscopy | study_record | in cell Unbreakable DNA tension probes show that cell adhesion receptors detect the molecular force-extension curve of their ligands · Fibronectin (FnIII domains); tension sensors; experiment class: nucleic_acid_mechanics, receptor_ligand_adhesion, rheology_cell, unfolding_nucleic_acid, unfolding_protein | unmapped |
| EV-SMASH-SMFS-001843 SMASH-BIO | force_spectroscopy | study_record | in vitro Cell mechanical properties of human breast carcinoma cells depend on temperature. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-002123 SMASH-BIO | force_spectroscopy | study_record | in vitro Seeing and Touching the Mycomembrane at the Nanoscale. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002220 SMASH-BIO | force_spectroscopy | study_record | in vitro A comparative analysis of detachment forces and energies in initial and mature cell-material interaction. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002233 SMASH-BIO | force_spectroscopy | study_record | in vitro Adhesion of Epithelial Cells to PNIPAm Treated Surfaces for Temperature-Controlled Cell-Sheet Harvesting. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002331 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Environmentally controlled magnetic nano-tweezer for living cells and extracellular matrices. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: rheology_cell | unmapped |
| EV-SMASH-SMFS-002394 SMASH-BIO | force_spectroscopy | study_record | in vitro Integration of Magnetic Tweezers and Traction Force Microscopy for the Exploration of Matrix Rheology and Keratinocyte Mechanobiology: Model Force- and Displacement-Controlled Experiments · Fibronectin (FnIII domains); magnetic tweezers; experiment class: receptor_ligand_adhesion, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-002415 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical Forces between Mycobacterial Antigen 85 Complex and Fibronectin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002493 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Probing fibronectin adsorption on chemically defined surfaces by means of single molecule force microscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-002497 SMASH-BIO | force_spectroscopy | study_record | in vitro Profiling Cell-Matrix Adhesion Using Digitalized Acoustic Streaming. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002693 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Distinct Binding Interactions of α5β1-Integrin and Proteoglycans with Fibronectin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002703-r0 SMASH-BIO | force_spectroscopy | adhesion_force: 0.64 nN ± 0.03 | in vitro Effect of monophasic pulsed stimulation on live single cell de-adhesion on conducting polymers with adsorbed fibronectin as revealed by single cell force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-002762 SMASH-BIO | force_spectroscopy | study_record | in vitro Investigation of Bacterial Curli Production and Adhesion Using AFM. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell, rheology_material | unmapped |
| EV-SMASH-SMFS-002826 SMASH-BIO | force_spectroscopy | study_record | in vitro Nanoprobe-based force spectroscopy as a versatile platform for probing the mechanical adhesion of bacteria. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-003050 SMASH-BIO | force_spectroscopy | study_record | in vitro Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003088-r0 SMASH-BIO | force_spectroscopy | adhesion_force: 0.65 nN | in vitro Effect of electrochemical oxidation and reduction on cell de-adhesion at the conducting polymer-live cell interface as revealed by single cell force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003088-r1 SMASH-BIO | force_spectroscopy | adhesion_force: 0.4 nN | in vitro Effect of electrochemical oxidation and reduction on cell de-adhesion at the conducting polymer-live cell interface as revealed by single cell force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003280-r0 SMASH-BIO | force_spectroscopy | loading_rate: 1500 pN/s | in vitro Single Molecule Force Spectroscopy Reveals Two-Domain Binding Mode of Pilus-1 Tip Protein RrgA of Streptococcus pneumoniae to Fibronectin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003280-r1 SMASH-BIO | force_spectroscopy | bond_lifetime: 0.26 s | in vitro Single Molecule Force Spectroscopy Reveals Two-Domain Binding Mode of Pilus-1 Tip Protein RrgA of Streptococcus pneumoniae to Fibronectin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003285 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-Cell Acoustic Force Spectroscopy: Resolving Kinetics and Strength of T Cell Adhesion to Fibronectin. · Fibronectin (FnIII domains); acoustic force spectroscopy; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003496 SMASH-BIO | force_spectroscopy | study_record | in vitro Evaluation of initial cell adhesion on poly (2-methoxyethyl acrylate) (PMEA) analogous polymers. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003500 SMASH-BIO | force_spectroscopy | study_record | in vitro Experimental and computational examination of anastellin (FnIII1c)-polymer interactions. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003508 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-003514 SMASH-BIO | force_spectroscopy | study_record | in vitro Force dependence of filopodia adhesion: involvement of myosin II and formins · Fibronectin (FnIII domains); optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003558 SMASH-BIO | force_spectroscopy | study_record | in vitro Investigating cell-substrate and cell-cell interactions by means of single-cell-probe force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003613 SMASH-BIO | force_spectroscopy | study_record | in vitro Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-003642 SMASH-BIO | force_spectroscopy | study_record | in vitro Plasma fibronectin stabilizes Borrelia burgdorferi-endothelial interactions under vascular shear stress by a catch-bond mechanism. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: force_generation_polymerization, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-003796 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 8 αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. · Fibronectin (FnIII domains); afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-003887 SMASH-BIO | force_spectroscopy | study_record | in vitro Elasticity, Adhesion, and Tether Extrusion on Breast Cancer Cells Provide a Signature of Their Invasive Potential. · Fibronectin (FnIII domains); afm smfs; experiment class: membrane_mechanics, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-004028 SMASH-BIO | force_spectroscopy | study_record | in vitro Reinforcement of integrin-mediated T-Lymphocyte adhesion by TNF-induced Inside-out Signaling. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004144 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Binding forces of Streptococcus mutans P1 adhesin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004155 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Characterization of monobody scaffold interactions with ligand via force spectroscopy and steered molecular dynamics. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004174 SMASH-BIO | force_spectroscopy | study_record | in vitro Determining the mechanical properties of plectin in mouse myoblasts and keratinocytes. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-004221 SMASH-BIO | force_spectroscopy | study_record | in vitro Force fluctuations in three-dimensional suspended fibroblasts. · Fibronectin (FnIII domains); optical tweezers; experiment class: force_generation_motor, force_generation_polymerization, rheology_cell | unmapped |
| EV-SMASH-SMFS-004336 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Probing fibronectin-antibody interactions using AFM force spectroscopy and lateral force microscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004477-r0 SMASH-BIO | force_spectroscopy | unfolding_force: 90 pN | in vitro · pH 7.5 Ca2+ binding enhanced mechanical stability of an archaeal crystallin. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-004477-r1 SMASH-BIO | force_spectroscopy | unfolding_force: 35 pN | in vitro · pH 7.5 Ca2+ binding enhanced mechanical stability of an archaeal crystallin. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-004483 SMASH-BIO | force_spectroscopy | study_record | in vitro Cell membrane deformation induced by a fibronectin-coated polystyrene microbead in a 200-MHz acoustic trap. · Fibronectin (FnIII domains); optical tweezers; experiment class: rheology_cell | unmapped |
| EV-SMASH-SMFS-004571 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Individual globular domains and domain unfolding visualized in overstretched titin molecules with atomic force microscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-004642 SMASH-BIO | force_spectroscopy | study_record | in vitro Nanomechanics of β-rich proteins related to neuronal disorders studied by AFM, all-atom and coarse-grained MD methods. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-004662 SMASH-BIO | force_spectroscopy | study_record | in vitro Plasticity of hydrogen bond networks regulates mechanochemistry of cell adhesion complexes. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: force_generation_motor, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004783 SMASH-BIO | force_spectroscopy | study_record | in vitro AFM imaging and analysis of local mechanical properties for detection of surface pattern of functional groups. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004796 SMASH-BIO | force_spectroscopy | study_record | in vitro Analysis of the REJ Module of Polycystin-1 Using Molecular Modeling and Force-Spectroscopy Techniques. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-004827 SMASH-BIO | force_spectroscopy | study_record | in vitro Cross-species mechanical fingerprinting of cardiac myosin binding protein-C. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: force_generation_motor, unfolding_protein | unmapped |
| EV-SMASH-SMFS-004859 SMASH-BIO | force_spectroscopy | study_record | in vitro Epithelial-mesenchymal transition enhances nanoscale actin filament dynamics of ovarian cancer cells. · Fibronectin (FnIII domains); afm smfs; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-004991 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing biofouling resistant polymer brush surfaces by atomic force microscopy based force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: force_generation_polymerization, receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004998 SMASH-BIO | force_spectroscopy | study_record | in vitro Quantifying cellular adhesion to covalently immobilized extracellular matrix proteins by single-cell force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005027-r0 SMASH-BIO | force_spectroscopy | adhesion_force: 1.25 nN ± 0.2 | in vitro · pH 8.5 Single-Cell Force Spectroscopy of Als-Mediated Fungal Adhesion. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005027-r1 SMASH-BIO | force_spectroscopy | adhesion_force: 2.8 nN ± 0.6 | in vitro · pH 8.5 Single-Cell Force Spectroscopy of Als-Mediated Fungal Adhesion. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005096 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.5 A rapid cloning method employing orthogonal end protection. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005120 SMASH-BIO | force_spectroscopy | study_record | in vitro Biomechanical characterization of a desminopathy in primary human myoblasts. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: chromatin_mechanics | unmapped |
| EV-SMASH-SMFS-005231 SMASH-BIO | force_spectroscopy | study_record | in vitro Low fibronectin concentration overcompensates for reduced initial fibroblasts adhesion to a nanoscale topography: single-cell force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005253 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanotransduction through fibronectin-integrin focal adhesion in microvascular smooth muscle cells: is calcium essential? · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005290 SMASH-BIO | force_spectroscopy | study_record | in vitro Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005306-r0 SMASH-BIO | force_spectroscopy | adhesion_force: 16 nN | in vitro · pH 7.4 Rapid and serial quantification of adhesion forces of yeast and Mammalian cells. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005306-r1 SMASH-BIO | force_spectroscopy | adhesion_force: 600 nN | in vitro · pH 7.4 Rapid and serial quantification of adhesion forces of yeast and Mammalian cells. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005395 SMASH-BIO | force_spectroscopy | study_record | in vitro Using molecular mechanics to predict bulk material properties of fibronectin fibers. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-005410 SMASH-BIO | force_spectroscopy | study_record | in vitro A microfluidic system with optical laser tweezers to study mechanotransduction and focal adhesion recruitment. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005542 SMASH-BIO | force_spectroscopy | study_record | in vitro Kinetic partitioning mechanism governs the folding of the third FnIII domain of tenascin-C: evidence at the single-molecule level. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-005563 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical unfolding of cardiac myosin binding protein-C by atomic force microscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: force_generation_motor, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005587 SMASH-BIO | force_spectroscopy | study_record | in vitro Negative feedback from integrins to cadherins: a micromechanical study. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005761 SMASH-BIO | force_spectroscopy | study_record | in vitro Detecting cell-adhesive sites in extracellular matrix using force spectroscopy mapping. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-005824 SMASH-BIO | force_spectroscopy | study_record | in vitro Isopeptide bonds block the mechanical extension of pili in pathogenic Streptococcus pyogenes. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005929 SMASH-BIO | force_spectroscopy | study_record | in vitro Stretching fibronectin fibres disrupts binding of bacterial adhesins by physically destroying an epitope. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-005940 SMASH-BIO | force_spectroscopy | study_record | in vitro Tertiary and secondary structure elasticity of a six-Ig titin chain. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-005953 SMASH-BIO | force_spectroscopy | study_record | in vitro The quantification of single cell adhesion on functionalized surfaces for cell sheet engineering. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006021 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.4 Demonstration of catch bonds between an integrin and its ligand. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006103-r0 SMASH-BIO | force_spectroscopy | unfolding_force: 20 pN | in vitro Mechanical design of the third FnIII domain of tenascin-C. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006120 SMASH-BIO | force_spectroscopy | study_record | in vitro Modulating the mechanical stability of extracellular matrix protein tenascin-C in a controlled and reversible fashion. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006203 SMASH-BIO | force_spectroscopy | study_record | in vitro Spatiotemporal analysis of cell response to a rigidity gradient: a quantitative study using multiple optical tweezers. · Fibronectin (FnIII domains); optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006270 SMASH-BIO | force_spectroscopy | study_record | in vitro BCR/ABL expression of myeloid progenitors increases beta1-integrin mediated adhesion to stromal cells. · Fibronectin (FnIII domains); afm smfs; experiment class: nucleic_acid_protein_interaction, receptor_ligand_adhesion, translation_transcription_replication | unmapped |
| EV-SMASH-SMFS-006359-r0 SMASH-BIO | force_spectroscopy | rupture_force: 17 pN | in vitro Interactions of the streptococcal C5a peptidase with human fibronectin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006421 SMASH-BIO | force_spectroscopy | study_record | in vitro Probing fibronectin-surface interactions: a multitechnique approach. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006471 SMASH-BIO | force_spectroscopy | study_record | in vitro Staphylococcus aureus SigB activity promotes a strong fibronectin-bacterium interaction which may sustain host tissue colonization by small-colony variants isolated from cystic fibrosis patients. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006498 SMASH-BIO | force_spectroscopy | study_record | in vitro Toward a molecular understanding of the anisotropic response of proteins to external forces: insights from elastic network models. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006526 SMASH-BIO | force_spectroscopy | study_record | in vitro Atomic force microscopy and surface plasmon resonance investigation of fibronectin interactions with group B streptococci. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-006700 SMASH-BIO | force_spectroscopy | study_record | in vitro Single-molecule dynamic force spectroscopy of the fibronectin-heparin interaction. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006711 SMASH-BIO | force_spectroscopy | study_record | in vitro Structure and reactivity of adsorbed fibronectin films on mica. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-006849-r0 SMASH-BIO | force_spectroscopy | loading_rate: 450 pN/s | in vitro Mechanics of cellular adhesion to artificial artery templates. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006849-r1 SMASH-BIO | force_spectroscopy | rupture_force: 20 pN | in vitro Mechanics of cellular adhesion to artificial artery templates. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006849-r2 SMASH-BIO | force_spectroscopy | rupture_force: 43 pN | in vitro Mechanics of cellular adhesion to artificial artery templates. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-006885 SMASH-BIO | force_spectroscopy | study_record | in vitro Rigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-006895 SMASH-BIO | force_spectroscopy | study_record | in vitro Single molecule force spectroscopy reveals a weakly populated microstate of the FnIII domains of tenascin. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006920 SMASH-BIO | force_spectroscopy | study_record | in vitro The molecular elasticity of the insect flight muscle proteins projectin and kettin. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-006926 SMASH-BIO | force_spectroscopy | study_record | in vitro Understanding the elasticity of fibronectin fibrils: unfolding strengths of FN-III and GFP domains measured by single molecule force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006949 SMASH-BIO | force_spectroscopy | study_record | in vitro Biophysical investigations of engineered polyproteins: implications for force data. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006954 SMASH-BIO | force_spectroscopy | study_record | in vitro Complex stability of single proteins explored by forced unfolding experiments. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006983 SMASH-BIO | force_spectroscopy | study_record | in vitro Force microscopy studies of fibronectin adsorption and subsequent cellular adhesion to substrates with well-defined surface chemistries. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-007012 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical unfolding intermediates observed by single-molecule force spectroscopy in a fibronectin type III module. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-007014 SMASH-BIO | force_spectroscopy | study_record | in vitro Mechanical unfolding of TNfn3: the unfolding pathway of a fnIII domain probed by protein engineering, AFM and MD simulation. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007027-r0 SMASH-BIO | force_spectroscopy | persistence_length: 0.3 nm | in vitro Myomesin is a molecular spring with adaptable elasticity. · Fibronectin (FnIII domains); afm smfs; experiment class: rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-007072 SMASH-BIO | force_spectroscopy | study_record | in vitro Study of the mechanical properties of myomesin proteins using dynamic force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007105-r0 SMASH-BIO | force_spectroscopy | rupture_force: 26 pN | in vitro Adherence of Staphylococcus aureus fibronectin binding protein A mutants: an investigation using optical tweezers. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007156 SMASH-BIO | force_spectroscopy | study_record | in vitro Microviscoelasticity of the apical cell surface of human umbilical vein endothelial cells (HUVEC) within confluent monolayers. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-007170 SMASH-BIO | force_spectroscopy | study_record | in vitro NrCAM coupling to the cytoskeleton depends on multiple protein domains and partitioning into lipid rafts. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-007257 SMASH-BIO | force_spectroscopy | study_record | in vitro Folding-unfolding of FN-III domains in tenascin: an elastically coupled two-state system. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007258 SMASH-BIO | force_spectroscopy | study_record | in vitro Force measurements of the alpha5beta1 integrin-fibronectin interaction. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007267 SMASH-BIO | force_spectroscopy | study_record | in vitro Interaction between chondroitin-6-sulfate and Entamoeba histolytica as revealed by force spectroscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007273 SMASH-BIO | force_spectroscopy | study_record | in vitro Measurement of adhesive forces between individual Staphylococcus aureus MSCRAMMs and protein-coated surfaces by use of optical tweezers. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007310 SMASH-BIO | force_spectroscopy | study_record | in vitro Staphylococcus epidermidis-fibronectin binding and its inhibition by heparin. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007355 SMASH-BIO | force_spectroscopy | study_record | in vitro Force spectroscopy study of the adhesion of plasma proteins to the surface of a dialysis membrane: role of the nanoscale surface hydrophobicity and topography. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007364 SMASH-BIO | force_spectroscopy | study_record | in vitro Measurement of adhesive forces between S. epidermidis and fibronectin-coated surfaces using optical tweezers. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007400 SMASH-BIO | force_spectroscopy | study_record | in vitro The mechanical hierarchies of fibronectin observed with single-molecule AFM. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007414 SMASH-BIO | force_spectroscopy | study_record | in vitro A new dimension in retrograde flow: centripetal movement of engulfed particles. · Fibronectin (FnIII domains); optical tweezers; experiment class: force_generation_motor, receptor_ligand_adhesion, rheology_cell | unmapped |
| EV-SMASH-SMFS-007440 SMASH-BIO | force_spectroscopy | study_record | in vitro Modeling AFM-induced PEVK extension and the reversible unfolding of Ig/FNIII domains in single and multiple titin molecules. · Fibronectin (FnIII domains); optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007446 SMASH-BIO | force_spectroscopy | study_record | in vitro Receptor-based differences in human aortic smooth muscle cell membrane stiffness. · Fibronectin (FnIII domains); magnetic tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007474 SMASH-BIO | force_spectroscopy | study_record | in vitro Computer modeling of force-induced titin domain unfolding. · Fibronectin (FnIII domains); optical tweezers; experiment class: rheology_cell, unfolding_protein | unmapped |
| EV-SMASH-SMFS-007500 SMASH-BIO | force_spectroscopy | study_record | in vitro Native topology determines force-induced unfolding pathways in globular proteins. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007513 SMASH-BIO | force_spectroscopy | study_record | in vitro Short-term binding of fibroblasts to fibronectin: optical tweezers experiments and probabilistic analysis. · Fibronectin (FnIII domains); optical tweezers; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-007532 SMASH-BIO | force_spectroscopy | study_record | in vitro Unfolding forces of titin and fibronectin domains directly measured by AFM. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007534 SMASH-BIO | force_spectroscopy | study_record | in vitro Unfolding proteins by external forces and temperature: the importance of topology and energetics. · Fibronectin (FnIII domains); optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007538 SMASH-BIO | force_spectroscopy | study_record | in vitro A kinetic molecular model of the reversible unfolding and refolding of titin under force extension. · Fibronectin (FnIII domains); optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007550 SMASH-BIO | force_spectroscopy | study_record | in vitro Forced unfolding of fibronectin type 3 modules: an analysis by biased molecular dynamics simulations. · Fibronectin (FnIII domains); optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007568 SMASH-BIO | force_spectroscopy | study_record | in vitro Single molecule force spectroscopy of spectrin repeats: low unfolding forces in helix bundles. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007618-r0 SMASH-BIO | force_spectroscopy | unfolding_force: 300 pN | in vitro The mechanical stability of immunoglobulin and fibronectin III domains in the muscle protein titin measured by atomic force microscopy. · Fibronectin (FnIII domains); afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-007619 SMASH-BIO | force_spectroscopy | study_record | in vitro The molecular elasticity of the extracellular matrix protein tenascin. · Fibronectin (FnIII domains); force spectroscopy unspecified; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-007633 SMASH-BIO | force_spectroscopy | study_record | in vitro Elasticity and unfolding of single molecules of the giant muscle protein titin. · Fibronectin (FnIII domains); optical tweezers; experiment class: nucleic_acid_protein_interaction, unfolding_protein | unmapped |
Conflicts
No conflicts found among comparable evidence.
216 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.