Superoxide dismutase [Cu-Zn]
UniProt P00441 · gene SOD1 · Homo sapiens · 154 residues
191evidence items
0mapped to a state
0states
7techniques
6sources
0conflicts
Coverage grid
Mapped evidence per state and technique. Shaded rows rest on a single technique. Badge = best data level in the cell: raw (traces, images, FIDs: can be re-analysed), proc (maps, curves, tables, trajectories) or rep (values in the paper only).
| State | Basis | xray | cryoem | nmr_structure | nmr_shifts | force_spectroscopy | af_prediction | md | Total |
|---|---|---|---|---|---|---|---|---|---|
| No states defined yet. | |||||||||
Unmapped evidence: 191 of 191 items. Mappings come from curator assignments and curated rules; see About for how rules work.
Sources
| Source | Evidence | Mapped |
|---|---|---|
| AlphaFold DB | 1 | 0 |
| BMRB | 12 | 0 |
| DisProt | 6 | 0 |
| MDDB | 1 | 0 |
| RCSB PDB | 163 | 0 |
| SMASH-BIO | 8 | 0 |
Structure
No state models are exported for this protein yet. Observed states export the representative PDB entry; inferred states need fitted models, not yet built.
States and transitions
No states defined.
| State | Basis | Parent | Description |
|---|
No transitions recorded in this version (no rate or free-energy evidence has been curated yet).
Evidence
One row per deposit or experiment. Filter by technique, environment or text. Unmapped evidence is listed too.
| Evidence | Technique | Observable | Conditions | Mapped to state |
|---|---|---|---|---|
| EV-PDB-1AZV-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · 26.85 °C · pH 5.5 · ligands CU, ZN FAMILIAL ALS MUTANT G37R CUZNSOD (HUMAN) · COPPER/ZINC SUPEROXIDE DISMUTASE (chains A,B) | unmapped |
| EV-PDB-1BA9-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 5 · ligands CU1, ZN THE SOLUTION STRUCTURE OF REDUCED MONOMERIC SUPEROXIDE DISMUTASE, NMR, 36 STRUCTURES · SUPEROXIDE DISMUTASE (chains A) | unmapped |
| EV-PDB-1DSW-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 5 · ligands CU, ZN THE SOLUTION STRUCTURE OF A MONOMERIC, REDUCED FORM OF HUMAN COPPER, ZINC SUPEROXIDE DISMUTASE BEARING THE SAME CHARGE AS THE NATIVE PROTEIN · SUPEROXIDE DISMUTASE (CU-ZN) (chains A) | unmapped |
| EV-PDB-1HL4-1 RCSB PDB | xray | resolution: 1.82 Å | in vitro · -173.15 °C · pH 8 · ligands ZN The Structure of Apo Type Human Cu, Zn Superoxide Dismutase · SUPEROXIDE DISMUTASE (chains A,B,C,D) | unmapped |
| EV-PDB-1HL5-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173.15 °C · pH 8 · ligands CA, CU, ZN The Structure of Holo Type Human Cu, Zn Superoxide Dismutase · SUPEROXIDE DISMUTASE (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,S) | unmapped |
| EV-PDB-1KMG-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 5 · ligands ZN The Solution Structure Of Monomeric Copper-free Superoxide Dismutase · Superoxide Dismutase (chains A) | unmapped |
| EV-PDB-1L3N-1 RCSB PDB | nmr_structure | structure | in vitro · 22.85 °C · pH 5 · ligands CU1, ZN The Solution Structure of Reduced Dimeric Copper Zinc SOD: the Structural Effects of Dimerization · superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-1MFM-1 RCSB PDB | xray | resolution: 1.02 Å | in vitro · -173.15 °C · pH 8 · ligands CD, CL, CU, ZN MONOMERIC HUMAN SOD MUTANT F50E/G51E/E133Q AT ATOMIC RESOLUTION · PROTEIN (COPPER,ZINC SUPEROXIDE DISMUTASE) (chains A) | unmapped |
| EV-PDB-1N18-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -183.15 °C · pH 7.5 · ligands CU1, SO4, ZN Thermostable mutant of Human Superoxide Dismutase, C6A, C111S · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-1N19-1 RCSB PDB | xray | resolution: 1.86 Å | in vitro · -183.15 °C · pH 7.5 · ligands CU1, SO4, ZN Structure of the HSOD A4V mutant · Superoxide Dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-1OZT-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · pH 6.5 Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution · Superoxide dismutase [Cu-Zn] (chains G,H,I,J,K,L,M,N) | unmapped |
| EV-PDB-1P1V-1 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 6.5 · ligands SO4, ZN Crystal Structure of FALS-associated human Copper-Zinc Superoxide Dismutase (CuZnSOD) Mutant D125H to 1.4A · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-1PTZ-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -177.15 °C · pH 7.5 · ligands CU1, SO4, ZN Crystal structure of the human CU, Zn Superoxide Dismutase, Familial Amyotrophic Lateral Sclerosis (FALS) Mutant H43R · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-1PU0-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -177.15 °C · pH 7.5 · ligands CU1, SO4, ZN Structure of Human Cu,Zn Superoxide Dismutase · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-1RK7-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 5 Solution structure of apo Cu,Zn Superoxide Dismutase: role of metal ions in protein folding · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-1SOS-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · ligands CU, SO4, ZN ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE · SUPEROXIDE DISMUTASE (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-1UXL-1 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 7.5 · ligands CU, SO4, ZN I113T mutant of human SOD1 · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-1UXM-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 6 · ligands CU, ZN A4V mutant of human SOD1 · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-23WU-1 RCSB PDB | xray | resolution: 2.7 Å | in vitro · -173.15 °C · pH 6.5 · ligands ZN Crystal structure of monomeric Cu/Zn-superoxide dismutase in complex with de novo designed binder (#313-604) · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-2AF2-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 5 · ligands ZN Solution structure of disulfide reduced and copper depleted Human Superoxide Dismutase · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-2C9S-1 RCSB PDB | xray | resolution: 1.24 Å | in vitro · -173.15 °C · pH 4.75 · ligands ACT, SO4, ZN 1.24 Angstroms resolution structure of Zn-Zn Human Superoxide dismutase · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2C9U-1 RCSB PDB | xray | resolution: 1.24 Å | in vitro · -173.15 °C · pH 8 · ligands ACT, CU, SO4, ZN 1.24 Angstroms resolution structure of as-isolated Cu-Zn Human Superoxide dismutase · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2C9V-1 RCSB PDB | xray | resolution: 1.07 Å | in vitro · -173.15 °C · pH 4.75 · ligands CU, NA, SO4, ZN Atomic resolution structure of Cu-Zn Human Superoxide dismutase · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2GBT-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 7.5 · ligands CU1, ZN C6A/C111A CuZn Superoxide dismutase · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-2GBU-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 6.5 C6A/C111A/C57A/C146A apo CuZn Superoxide dismutase · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-2GBV-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 7.5 · ligands CU1, ZN C6A/C111A/C57A/C146A holo CuZn Superoxide dismutase · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-2LU5-1 RCSB PDB | nmr_structure | structure | in vitro · 12.85 °C · pH 5 · ligands CU Structure and chemical shifts of Cu(I),Zn(II) superoxide dismutase by solid-state NMR · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-2MP3-1 RCSB PDB | nmr_structure | structure | in vitro · 39.85 °C · pH 4 Truncated L126Z-sod1 in DPC micelle · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-2NAM-1 RCSB PDB | nmr_structure | structure | in vitro · 39.85 °C · pH 4 Full-length WT SOD1 in DPC MICELLE · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-2NNX-1 RCSB PDB | xray | resolution: 2.3 Å | in vitro · -173.15 °C · pH 5.8 · ligands SO4, ZN Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,B,C,D) | unmapped |
| EV-PDB-2R27-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 7.5 · ligands CU Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-2V0A-1 RCSB PDB | xray | resolution: 1.15 Å | in vitro · -173.15 °C · pH 4.75 · ligands ACT, CU, SO4, ZN Atomic resolution crystal structure of Human Superoxide Dismutase · SUPEROXIDE DISMUTASE (chains A,F) | unmapped |
| EV-PDB-2VR6-1 RCSB PDB | xray | resolution: 1.3 Å | in vitro · -173.15 °C · pH 7 · ligands CU, SCN, SO4, ZN Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2VR7-1 RCSB PDB | xray | resolution: 1.58 Å | in vitro · -173.15 °C · pH 7 · ligands CU, SCN, SO4, ZN Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2VR8-1 RCSB PDB | xray | resolution: 1.36 Å | in vitro · -173.15 °C · pH 7 · ligands CU, SCN, SO4, ZN Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.36 A resolution · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2WKO-2 RCSB PDB | xray | resolution: 1.97 Å | in vitro · -173.15 °C · pH 6.5 · ligands CU, IOD, ZN Structure of metal loaded Pathogenic SOD1 Mutant G93A. · SUPEROXIDE DISMUTASE [CU-ZN] (chains F) | unmapped |
| EV-PDB-2WKO-1 RCSB PDB | xray | resolution: 1.97 Å | in vitro · -173.15 °C · pH 6.5 · ligands CU, IOD, ZN Structure of metal loaded Pathogenic SOD1 Mutant G93A. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A) | unmapped |
| EV-PDB-2WYT-1 RCSB PDB | xray | resolution: 1 Å | in vitro · -173.15 °C · pH 4.75 · ligands ACT, CL, CU, SO4, ZN 1.0 A resolution structure of L38V SOD1 mutant · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2WYZ-1 RCSB PDB | xray | resolution: 1.7 Å | in vitro · -173.15 °C · pH 7.5 · ligands CU, SO4, U5P, ZN L38V SOD1 mutant complexed with UMP · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2WZ0-1 RCSB PDB | xray | resolution: 1.72 Å | in vitro · -173.15 °C · pH 7.5 · ligands CU, DMS, DSN, SO4, ZN, ZZT L38V SOD1 mutant complexed with aniline. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2WZ5-1 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 4.75 · ligands CU, MET, SO4, ZN L38V SOD1 mutant complexed with L-methionine. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2WZ6-1 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · pH 4.75 · ligands CU, SO4, ZN, ZO0 G93A SOD1 mutant complexed with Quinazoline. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-2ZKW-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 6.2 · ligands CU1, ZN Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group P21 · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-2ZKX-1 RCSB PDB | xray | resolution: 2.72 Å | in vitro · -173.15 °C · pH 4.6 · ligands CU1, ZN Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group I212121 · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-2ZKY-1 RCSB PDB | xray | resolution: 2.4 Å | in vitro · -173.15 °C · pH 6.5 · ligands ZN Crystal structure of human Cu-Zn superoxide dismutase mutant G93A · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-2XJL-1 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · pH 5 · ligands ACT, NA, PEG, ZN Monomeric Human Cu,Zn Superoxide dismutase without Cu ligands · SUPEROXIDE DISMUTASE [CU-ZN] (chains A) | unmapped |
| EV-PDB-2XJK-1 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · pH 6 · ligands CU, ZN Monomeric Human Cu,Zn Superoxide dismutase · SUPEROXIDE DISMUTASE [CU-ZN] (chains A) | unmapped |
| EV-PDB-1SPD-1 RCSB PDB | xray | resolution: 2.4 Å | in vitro · ligands CU, ZN AMYOTROPHIC LATERAL SCLEROSIS AND STRUCTURAL DEFECTS IN CU,ZN SUPEROXIDE DISMUTASE · SUPEROXIDE DISMUTASE (chains A,B) | unmapped |
| EV-PDB-1OZU-1 RCSB PDB | xray | resolution: 1.3 Å | in vitro · -173.15 °C · pH 7 · ligands SO4, ZN Crystal Structure of Familial ALS Mutant S134N of human Cu,Zn Superoxide Dismutase (CuZnSOD) to 1.3A resolution · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-1OEZ-1 RCSB PDB | xray | resolution: 2.15 Å | in vitro · -173.15 °C · pH 8 · ligands SO4, ZN Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase · SUPEROXIDE DISMUTASE [CU-ZN] (chains W,X,Y,Z) | unmapped |
| EV-PDB-1FUN-1 RCSB PDB | xray | resolution: 2.85 Å | in vitro · 13.85 °C · pH 7 · ligands CU, SO4, ZN SUPEROXIDE DISMUTASE MUTANT WITH LYS 136 REPLACED BY GLU, CYS 6 REPLACED BY ALA AND CYS 111 REPLACED BY SER (K136E, C6A, C111S) · SUPEROXIDE DISMUTASE (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-3ECU-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 6.5 Crystal structure of human apo Cu,Zn Superoxide Dismutase (SOD1) · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-3ECV-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 6.5 Crystal structure of the ALS-related pathological mutant I113T of human apo Cu,Zn Superoxide Dismutase (SOD1) · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-3ECW-1 RCSB PDB | xray | resolution: 2.15 Å | in vitro · -173.15 °C · pH 7 Crystal structure of the ALS-related pathological mutant T54R of human apo Cu,Zn Superoxide Dismutase (SOD1) · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-3GTV-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -173.15 °C · pH 7.5 · ligands ZN Human-mouse SOD1 chimera · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-3GZP-1 RCSB PDB | xray | resolution: 3.1 Å | in vitro · -173.15 °C · pH 7 HUMAN SOD1 G93A Metal-free Variant · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-3KH4-1 RCSB PDB | xray | resolution: 3.5 Å | in vitro · -173.15 °C · ligands CU, ZN Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P6522 crystal form containing 6 chains in the asymmetric unit · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-3LTV-1 RCSB PDB | xray | resolution: 2.453 Å | in vitro · -173.15 °C · pH 4.6 · ligands ZN Mouse-human sod1 chimera · Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-3T5W-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173.15 °C · pH 6 · ligands CU1, SO4, ZN 2ME modified human SOD1 · Superoxide dismutase [Cu-Zn] (chains A,B,D,E,F,G,H,I,J,K,L,M) | unmapped |
| EV-PDB-4A7S-1 RCSB PDB | xray | resolution: 1.06 Å | in vitro · -173.15 °C · pH 5 · ligands 5UD, ACT, CU, SO4, ZN Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-4A7V-1 RCSB PDB | xray | resolution: 1 Å | in vitro · -173.15 °C · pH 5 · ligands CU, LDP, SO4, ZN Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-4MCM-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -173.15 °C · pH 5.5 · ligands SO4, ZN Human SOD1 C57S Mutant, As-isolated · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-4NIP-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 4.5 GVIGIAQ segment 147-153 from Human Superoxide Dismutase · GVTGIAQ segment from Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-5O3Y-1 RCSB PDB | xray | resolution: 1.3 Å | in vitro · -173.15 °C · pH 3.75 · ligands 9JK, SO4, ZN SOD1 bound to Ebsulfur · Superoxide dismutase [Cu-Zn] (chains A,F) | unmapped |
| EV-PDB-5O40-1 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 4 · ligands 9JT, SO4, ZN SOD1 bound to Ebselen · Superoxide dismutase [Cu-Zn] (chains A,F) | unmapped |
| EV-PDB-5WOR-1 RCSB PDB | xray | resolution: 2.77 Å | in vitro · -173.15 °C · pH 7 · ligands GOL, MLI Corkscrew assembly of SOD1 residues 28-38 with familial mutation G37R · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-5WMJ-1 RCSB PDB | xray | resolution: 1.4 Å | in vitro · 24.85 °C · pH 7 · ligands TFA KVWGSI segment from Superoxide Dismutase 1,residues 30-35 · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-5U9M-1 RCSB PDB | xray | resolution: 2.35 Å | in vitro · -173.15 °C · ligands ZN Copper-Zinc Superoxide Dismutase is Activated through a Sulfenic Acid Intermediate at a Copper-ion Entry Site · Superoxide dismutase [Cu-Zn] (chains A,C) | unmapped |
| EV-PDB-5K02-1 RCSB PDB | xray | resolution: 1.99 Å | in vitro · -173.15 °C · pH 6.5 · ligands CU, ZN Structure of human SOD1 with T2D mutation · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X) | unmapped |
| EV-PDB-5J0G-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8 · OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-5J0F-1 RCSB PDB | xray | resolution: 1.25 Å | in vitro · -173.15 °C · ligands GOL Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P4/5 · Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-5J0C-1 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 5 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3 · Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-5J07-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 5 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2 · Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-5IIW-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 5 Corkscrew assembly of SOD1 residues 28-38 without potassium iodide · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H) | unmapped |
| EV-PDB-5DLI-1 RCSB PDB | xray | resolution: 2.1 Å | in vitro · -173.15 °C · pH 5 · ligands GOL, IOD Corkscrew assembly of SOD1 residues 28-38 · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H) | unmapped |
| EV-PDB-4XCR-1 RCSB PDB | xray | resolution: 3.602 Å | in vitro · -173.15 °C · pH 5.5 Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-4OH2-1 RCSB PDB | xray | resolution: 2.384 Å | in vitro · -173.15 °C · pH 7.6 · ligands CU, ZN Crystal Structure of Cu/Zn Superoxide Dismutase I149T · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-4NIO-1 RCSB PDB | xray | resolution: 1.3 Å | in vitro · -173.15 °C · pH 4.5 GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis · GVTGIAQ segment from Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-4NIN-1 RCSB PDB | xray | resolution: 1.402 Å | in vitro · -173.15 °C · pH 6 · ligands ZN DSVISLS segment 101-107 from Human Superoxide Dismutase · DSVISLS segment from Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-4MCN-1 RCSB PDB | xray | resolution: 2.6 Å | in vitro · -173.15 °C · pH 6 · ligands SO4 Human SOD1 C57S Mutant, Metal-free · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-4FF9-1 RCSB PDB | xray | resolution: 2.5003 Å | in vitro · -173.15 °C · pH 6.25 · ligands CU, CYS, ZN Crystal Structure of cysteinylated WT SOD1. · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-4BD4-1 RCSB PDB | xray | resolution: 2.78 Å | in vitro · -173.15 °C · ligands GOL Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,B,C,D,E,F,G,H,I) | unmapped |
| EV-PDB-4BCZ-1 RCSB PDB | xray | resolution: 1.93 Å | in vitro · -173.15 °C Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,B) | unmapped |
| EV-PDB-4BCY-1 RCSB PDB | xray | resolution: 1.272 Å | in vitro · -173.15 °C · ligands CD, CL, CU, ZN Monomeric Human Cu,Zn Superoxide dismutase, mutation H43F · SUPEROXIDE DISMUTASE [CU-ZN] (chains A) | unmapped |
| EV-PDB-4B3E-1 RCSB PDB | xray | resolution: 2.15 Å | in vitro · -173.15 °C · pH 7.5 · ligands CO3, CU, SO4, ZN Structure of copper-zinc superoxide dismutase complexed with bicarbonate. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-4A7U-1 RCSB PDB | xray | resolution: 0.98 Å | in vitro · -173.15 °C · pH 5 · ligands ACT, ALE, CU, SO4, ZN Structure of human I113T SOD1 complexed with adrenaline in the p21 space group. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-4A7T-1 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · pH 5 · ligands 5FW, ACT, CU, SO4, ZN Structure of human I113T SOD1 mutant complexed with isoproteranol in the p21 space group · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-4A7Q-1 RCSB PDB | xray | resolution: 1.22 Å | in vitro · -173.15 °C · pH 5 · ligands 4MQ, CU, SO4, ZN Structure of human I113T SOD1 mutant complexed with 4-(4-methyl-1,4- diazepan-1-yl)quinazoline in the p21 space group. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F) | unmapped |
| EV-PDB-4A7G-2 RCSB PDB | xray | resolution: 1.24 Å | in vitro · -173.15 °C · pH 5 · ligands 12I, ACT, CU, SO4, ZN Structure of human I113T SOD1 mutant complexed with 4-methylpiperazin- 1-yl)quinazoline in the p21 space group. · SUPEROXIDE DISMUTASE [CU-ZN] (chains F) | unmapped |
| EV-PDB-4A7G-1 RCSB PDB | xray | resolution: 1.24 Å | in vitro · -173.15 °C · pH 5 · ligands 12I, ACT, CU, SO4, ZN Structure of human I113T SOD1 mutant complexed with 4-methylpiperazin- 1-yl)quinazoline in the p21 space group. · SUPEROXIDE DISMUTASE [CU-ZN] (chains A) | unmapped |
| EV-PDB-3RE0-1 RCSB PDB | xray | resolution: 2.28 Å | in vitro · -173.15 °C · pH 7.5 · ligands CPT Crystal structure of human apo Cu,Zn superoxide dismutase (SOD1) complexed with cisplatin · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-3QQD-2 RCSB PDB | xray | resolution: 1.653 Å | in vitro · -173.15 °C · pH 8 · ligands SO4, ZN Human SOD1 H80R variant, P212121 crystal form · Superoxide dismutase [Cu-Zn] (chains B) | unmapped |
| EV-PDB-3QQD-1 RCSB PDB | xray | resolution: 1.653 Å | in vitro · -173.15 °C · pH 8 · ligands SO4, ZN Human SOD1 H80R variant, P212121 crystal form · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-3KH3-1 RCSB PDB | xray | resolution: 3.5 Å | in vitro · -173.15 °C · ligands CU, SO4, ZN Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-3K91-1 RCSB PDB | xray | resolution: 1.75 Å | in vitro · -173.15 °C · pH 4.6 · ligands PS5 Polysulfane Bridge in Cu-Zn Superoxide Dismutase · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-3HFF-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -173.15 °C · pH 8 · ligands ZN Monomeric human Cu,Zn Superoxide dismutase without Zn ligands · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-3H2Q-1 RCSB PDB | xray | resolution: 1.85 Å | in vitro · -173.15 °C · pH 8 · ligands SO4, ZN Human SOD1 H80R variant, P21 crystal form · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-3H2P-1 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · pH 7 · ligands ACE, MLI, ZN Human SOD1 D124V Variant · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-3GZQ-1 RCSB PDB | xray | resolution: 1.401 Å | in vitro · -173.15 °C · pH 6 · ligands SO4 HUMAN SOD1 A4V Metal-free Variant · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-3GZO-1 RCSB PDB | xray | resolution: 2.1 Å | in vitro · -173.15 °C · pH 6 · ligands CU, GOL, MLI, ZN HUMAN SOD1 G93A Variant · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-3GQF-1 RCSB PDB | xray | resolution: 2.2 Å | in vitro · -173.15 °C · pH 8 · ligands CA, ZN Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F) | unmapped |
| EV-PDB-3CQQ-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · pH 7 · ligands ACE, ZN Human SOD1 G85R Variant, Structure II · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-3CQP-1 RCSB PDB | xray | resolution: 1.95 Å | in vitro · -173.15 °C · pH 7 · ligands CU, MLI, ZN Human SOD1 G85R Variant, Structure I · Superoxide dismutase [Cu-Zn] (chains A,B,C,D) | unmapped |
| EV-PDB-6A9O-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · ligands 6B3, DMS, GOL, S4P, ZN Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-6B79-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173.15 °C · pH 7.5 · ligands ORA Curved pair of sheets formed from SOD1 residues 28-38 with familial mutation G37R. · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-6DTK-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · ligands CU, MLI, ZN Heterodimers of FALS mutant SOD enzyme · Superoxide dismutase C111S/D83S-C111S HETERODIMER (chains A,C,E,G,I) | unmapped |
| EV-PDB-6FLH-1 RCSB PDB | xray | resolution: 1.79 Å | in vitro · -173.15 °C · ligands GOL, SO4 Monomeric Human Cu,Zn Superoxide dismutase, SOD1 7+7, apo form · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-6Z3V-1 RCSB PDB | xray | resolution: 1.25 Å | in vitro · -173.15 °C · pH 4.7 · ligands Q6H, SO4, ZN A4V mutant of human SOD1 bound with N-aryl benzoisoselenazolone derivative 13 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-6Z4G-1 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · pH 4.7 · ligands 9JT, ACT, CL, SO4, ZN A4V mutant of human SOD1 bound with ebselen in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-6Z4M-1 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · pH 4.7 · ligands CL, Q8E, SO4, ZN A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 10 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-7CJV-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6.3 Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a dilute environment · Monomeric Human Cu,Zn Superoxide dismutase (chains A) | unmapped |
| EV-PDB-9IYJ-1 RCSB PDB | cryoem | resolution: 2.92 Å | in vitro Cryo-EM structure of an amyloid fibril formed by SOD1 mutant - D101N · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-9IYD-1 RCSB PDB | cryoem | resolution: 3.09 Å | in vitro Cryo-EM structure of an amyloid fibril formed by SOD1 mutant - G93A · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-8YD3-1 RCSB PDB | xray | resolution: 1.96 Å | in vitro · 19.85 °C · pH 6.5 · ligands A1LYN, GOL, ZN Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-8YAT-1 RCSB PDB | xray | resolution: 3.94 Å | in vitro · -173.15 °C · ligands ZN SOD1, Nanobody1, Nanobody2 and Nanobody3 complex · Superoxide dismutase [Cu-Zn] (chains A,E,I,M) | unmapped |
| EV-PDB-8YAF-1 RCSB PDB | xray | resolution: 3.28 Å | in vitro · -173.15 °C · ligands ZN SOD1, Nanobody1 and Nanobody2 complex · Superoxide dismutase [Cu-Zn] (chains A,D,H,L,P,T) | unmapped |
| EV-PDB-8Q6M-1 RCSB PDB | xray | resolution: 1.77 Å | in vitro · -173.15 °C · pH 4.75 · ligands ACT, CU, SO4, ZN Human SOD1 low dose data collecton · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-8K3L-1 RCSB PDB | xray | resolution: 2.3 Å | in vitro · -173.15 °C · ligands CU, ZN SOD1 and Nanobody3 complex · Superoxide dismutase [Cu-Zn] (chains A,C,E,G) | unmapped |
| EV-PDB-8K3A-1 RCSB PDB | xray | resolution: 2.74 Å | in vitro · -173.15 °C · ligands ZN SOD1 and Nanobody2 complex · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-8K33-1 RCSB PDB | xray | resolution: 2.13 Å | in vitro · -173.15 °C · pH 8.5 · ligands ZN SOD1 and Nanobody1 complex · Superoxide dismutase [Cu-Zn] (chains A,C,E,G,I,K,L,N,P,U,W,Y) | unmapped |
| EV-PDB-8IHV-1 RCSB PDB | cryoem | resolution: 3.11 Å | in vitro Cryo-EM structure of an amyloid fibril formed by ALS-causing SOD1 mutation H46R · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-8IHU-1 RCSB PDB | cryoem | resolution: 2.97 Å | in vitro Cryo-EM structure of an amyloid fibril formed by ALS-causing SOD1 mutation G85R · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-8GSQ-4 RCSB PDB | xray | resolution: 2.1 Å | in vitro · 19.85 °C · pH 6.5 · ligands GOL, K4I, ZN Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. · Superoxide dismutase [Cu-Zn] (chains H) | unmapped |
| EV-PDB-8GSQ-3 RCSB PDB | xray | resolution: 2.1 Å | in vitro · 19.85 °C · pH 6.5 · ligands GOL, K4I, ZN Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. · Superoxide dismutase [Cu-Zn] (chains E,G) | unmapped |
| EV-PDB-8GSQ-2 RCSB PDB | xray | resolution: 2.1 Å | in vitro · 19.85 °C · pH 6.5 · ligands GOL, K4I, ZN Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. · Superoxide dismutase [Cu-Zn] (chains C) | unmapped |
| EV-PDB-8GSQ-1 RCSB PDB | xray | resolution: 2.1 Å | in vitro · 19.85 °C · pH 6.5 · ligands GOL, K4I, ZN Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. · Superoxide dismutase [Cu-Zn] (chains A,B,D,F,I,J) | unmapped |
| EV-PDB-8CCX-1 RCSB PDB | xray | resolution: 1.665 Å | in vitro · -173.15 °C · pH 4.75 · ligands CU, DMS, SO4, UDI, ZN Human SOD1 in complex with S-XL6 cross-linker · Superoxide dismutase [Cu-Zn] (chains A,F) | unmapped |
| EV-PDB-7XX3-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -192.15 °C · pH 6.5 · ligands DMS, GOL, I2G, ZN Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-7VZF-1 RCSB PDB | cryoem | resolution: 2.95 Å | in vitro Cryo-EM structure of amyloid fibril formed by full-length human SOD1 · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-7T8H-1 RCSB PDB | xray | resolution: 1.5 Å | in vitro · -173.15 °C · pH 4.7 · ligands ACT, Q8E, SO4, ZN G93A mutant of human SOD1 bound with MR6-26-2 in P21 space group · Superoxide dismutase [Cu-Zn] (chains A,F) | unmapped |
| EV-PDB-7T8G-1 RCSB PDB | xray | resolution: 1.35 Å | in vitro · -173.15 °C · pH 4.7 · ligands ACT, Q8H, SE, SO4, ZN G93A mutant of human SOD1 bound with MR6-8-2 in P21 space group · Superoxide dismutase [Cu-Zn] (chains A,F) | unmapped |
| EV-PDB-7T8F-1 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 4.7 · ligands 9JT, ACT, ZN G93A mutant of human SOD1 bound with Ebselen in P21 space group · Superoxide dismutase [Cu-Zn] (chains A,F) | unmapped |
| EV-PDB-7T8E-1 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 4.7 · ligands ACT, SO4, ZN G93A mutant of human SOD1 in P21 space group · Superoxide dismutase [Cu-Zn] (chains A,F) | unmapped |
| EV-PDB-7NXX-1 RCSB PDB | xray | resolution: 2.189 Å | in vitro · -193.15 °C · ligands CU, ZN Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). · Superoxide dismutase [Cu-Zn] (chains A) | unmapped |
| EV-PDB-7FB9-1 RCSB PDB | xray | resolution: 2.7 Å | in vitro · -173 °C · ligands CU, ZN Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N) | unmapped |
| EV-PDB-7FB6-1 RCSB PDB | xray | resolution: 1.8 Å | in vitro · -173 °C · ligands CL, CU, ZN C57D/C146D mutant of Human Cu, Zn Superoxide Dismutase (SOD1) · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-7CJW-1 RCSB PDB | nmr_structure | structure | in vitro · 24.85 °C · pH 6.3 Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment · Monomeric Human Cu,Zn Superoxide dismutase (chains A) | unmapped |
| EV-PDB-6Z4O-1 RCSB PDB | xray | resolution: 1.4 Å | in vitro · -173.15 °C · pH 4.7 · ligands Q7T, SO4, ZN A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 1 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-6Z4L-1 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 4.7 · ligands Q8H, SO4, ZN A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 9 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-6Z4K-1 RCSB PDB | xray | resolution: 1.45 Å | in vitro · -173.15 °C · pH 4.7 · ligands CL, Q7N, ZN A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 6 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-6Z4J-1 RCSB PDB | xray | resolution: 1.55 Å | in vitro · -173.15 °C · pH 4.7 · ligands CL, Q7W, ZN A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 5 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-6Z4I-1 RCSB PDB | xray | resolution: 1.6 Å | in vitro · -173.15 °C · pH 4.7 · ligands ACT, Q85, SO4, ZN A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 3 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,FFF) | unmapped |
| EV-PDB-6Z4H-1 RCSB PDB | xray | resolution: 1.95 Å | in vitro · -173.15 °C · pH 4.7 · ligands LQW, SO4, ZN A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 2 in P21 space group · Superoxide dismutase [Cu-Zn] (chains AAA,BBB) | unmapped |
| EV-PDB-6SPK-1 RCSB PDB | xray | resolution: 2.77 Å | in vitro · -173.15 °C · pH 7.6 · ligands CL, DMS, GOL, LQN, NA, SO4, ZN A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6 · Superoxide dismutase [Cu-Zn] (chains A,B,E,F,I,J) | unmapped |
| EV-PDB-6SPJ-1 RCSB PDB | xray | resolution: 1.97 Å | in vitro · -173.15 °C · pH 7.6 · ligands CL, DMS, GOL, LR2, SO4, ZN A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 1 · Superoxide dismutase [Cu-Zn] (chains A,B,E,F,I,J) | unmapped |
| EV-PDB-6SPI-1 RCSB PDB | xray | resolution: 2.8 Å | in vitro · -173.15 °C · pH 7.6 · ligands LQW, SO4, ZN A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-6SPH-1 RCSB PDB | xray | resolution: 2.25 Å | in vitro · -173.15 °C · ligands 9JT, DMS, GOL, SO4, ZN A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 WITH EBSELEN BOND IN C2 SPACE GROUP · Superoxide dismutase [Cu-Zn] (chains A,C,E,G,J,L) | unmapped |
| EV-PDB-6SPA-1 RCSB PDB | xray | resolution: 1.65 Å | in vitro · -173.15 °C · ligands DMS, GOL, SO4, ZN A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 IN C2 SPACE GROUP · Superoxide dismutase [Cu-Zn] (chains A,C,E,G,J,L) | unmapped |
| EV-PDB-6FP6-1 RCSB PDB | xray | resolution: 3 Å | in vitro · -173.15 °C · ligands GOL, PPI, ZN Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation · Superoxide dismutase [Cu-Zn] (chains A,C,E,G,I,K,M,O,Q,S,U,W) | unmapped |
| EV-PDB-6FON-2 RCSB PDB | xray | resolution: 3.05 Å | in vitro · -173.15 °C · pH 6 · ligands ZN Elongated conformer of the human copper chaperone for SOD1 complexed with human SOD1 · Superoxide dismutase [Cu-Zn] (chains B,D) | unmapped |
| EV-PDB-6FOL-2 RCSB PDB | xray | resolution: 2.55 Å | in vitro · -173.15 °C · ligands GOL, PE8, ZN Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase · Superoxide dismutase [Cu-Zn] (chains B,C,F,G) | unmapped |
| EV-PDB-6FOI-1 RCSB PDB | xray | resolution: 2 Å | in vitro · -173.15 °C · pH 8 · ligands SO4, ZN Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. · Superoxide dismutase [Cu-Zn] (chains A,D,F,G,I,K,M,O,Q,S,U,W) | unmapped |
| EV-PDB-6FFK-1 RCSB PDB | xray | resolution: 1.94 Å | in vitro · -173.15 °C · pH 7 · ligands D7Z Human apo-SOD1 bound to PtCl2(1R,2R-1,4-DACH · Superoxide dismutase [Cu-Zn] (chains A,B,D,F) | unmapped |
| EV-PDB-5YUL-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · ligands GOL, S4P, ZN Native Structure of hSOD1 in P6322 space group · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-5YTU-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · ligands 5FW, GOL, S4P, TAM, ZN Structure of human SOD1 complexed with isoproteranol in C2221 space group · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-5YTO-1 RCSB PDB | xray | resolution: 1.9 Å | in vitro · -173.15 °C · ligands 946, GOL, PS5, ZN Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound. · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-9IYK-1 RCSB PDB | xray | resolution: 2.34 Å | in vitro · -173.15 °C · ligands ACT, CU, SO4, ZN Crystal structure of hSOD1 in C121 space group · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L) | unmapped |
| EV-PDB-9JBO-1 RCSB PDB | cryoem | resolution: 3.39 Å | in vitro Cryo-EM structure of human SOD1 (WT) amyloid filament · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-9LI1-1 RCSB PDB | cryoem | resolution: 4.74 Å | in vitro Cryo-EM structure of human SOD1 (G93A) amyloid filament · Superoxide dismutase [Cu-Zn] (chains A,B,C) | unmapped |
| EV-PDB-9MIL-1 RCSB PDB | xray | resolution: 2.5 Å | in vitro · -173.15 °C · pH 5.5 · ligands PEG, PG4, SO4 Superoxide dismutase residues 28-39 with G37R mutation · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J) | unmapped |
| EV-PDB-9XJ0-1 RCSB PDB | xray | resolution: 2.3 Å | in vitro · 19.85 °C · ligands CU, ZN Crystal structure of SOD1 by serial synchrotron crystallography · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-9XJI-1 RCSB PDB | xray | resolution: 2.37 Å | in vitro · -173.15 °C · ligands CU, ZN Cryogenic structure of SOD1, determined as the SSX counterpart · Superoxide dismutase [Cu-Zn] (chains A,B) | unmapped |
| EV-PDB-9JBP-1 RCSB PDB | cryoem | resolution: 3.18 Å | in vitro Cryo-EM structure of human SOD1 (C6A/C111A) amyloid filament · Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F) | unmapped |
| EV-BMRB-15711 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.3 Backbone chemical shift assignements for monomeric apoSOD1 · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-18509 BMRB | nmr_shifts | chemical_shift | in vitro · 12.85 °C · pH 5 Structure and chemical shifts of Cu(I),Zn(II) superoxide dismutase by solid-state NMR · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-18708 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C Structure of Co-substituted microcrystalline SOD using PCS and PRE restraints by solid-state NMR · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-18968 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.3 Diffuse binding of Zn2+ to the denatured ensemble of Cu/Zn superoxide dismutase 1 · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-19962 BMRB | nmr_shifts | chemical_shift | in vitro · 39.85 °C · pH 4 Truncated L126Z-sod1 in DPC micelle · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-25942 BMRB | nmr_shifts | chemical_shift | in vitro · 39.85 °C · pH 4 Full-length WT SOD1 in DPC MICELLE · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-26570 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 7.4 Backbone and sidechain 1H, 13C and 15N chemical shifts for human superoxide dismutase (hSOD1) lacking bound metal and the intrasubunit disulfide bond · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-36359 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.3 Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a dilute environment · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-36360 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 6.3 Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-6821 BMRB | nmr_shifts | chemical_shift | in vitro · 24.85 °C · pH 5 Human SOD before harboring the catalytic metal: Solution structure of copper depleted, disulfide reduced form · BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts | unmapped |
| EV-BMRB-813 BMRB | nmr_shifts | chemical_shift | in vitro · 26.85 °C · pH 5.3 Investigation of Copper-Zinc Superoxide Dismutase Ser-137 and Ala-137 Mutants · BMRB data: 1H chemical shifts | unmapped |
| EV-BMRB-814 BMRB | nmr_shifts | chemical_shift | in vitro · 26.85 °C · pH 5.3 Investigation of Copper-Zinc Superoxide Dismutase Ser-137 and Ala-137 Mutants · BMRB data: 1H chemical shifts | unmapped |
| EV-DISPROT-DP00652r001 DisProt | xray | disorder_region: 10 residues | in vitro DisProt DP00652: disorder, residues 69-78 · residues 69-78; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion | unmapped |
| EV-DISPROT-DP00652r003 DisProt | xray | disorder_region: 16 residues | in vitro DisProt DP00652: disorder, residues 127-142 · residues 127-142; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion | unmapped |
| EV-DISPROT-DP00652r005 DisProt | xray | disorder_region: 16 residues | in vitro DisProt DP00652: order, residues 127-142 · residues 127-142; evidence: x-ray crystallography evidence used in manual assertion | unmapped |
| EV-DISPROT-DP00652r006 DisProt | xray | disorder_region: 10 residues | in vitro DisProt DP00652: order, residues 69-78 · residues 69-78; evidence: x-ray crystallography evidence used in manual assertion | unmapped |
| EV-DISPROT-DP00652r007 DisProt | xray | disorder_region: 10 residues | in vitro DisProt DP00652: disorder to order, residues 69-78 · residues 69-78; evidence: x-ray crystallography evidence used in manual assertion | unmapped |
| EV-DISPROT-DP00652r008 DisProt | xray | disorder_region: 16 residues | in vitro DisProt DP00652: disorder to order, residues 127-142 · residues 127-142; evidence: x-ray crystallography evidence used in manual assertion | unmapped |
| EV-AFDB-AF-P00441-F1 AlphaFold DB | af_prediction | plddt: 97.94 pLDDT | in silico AlphaFold DB prediction AF-P00441-F1 · AlphaFold Monomer v2.0 pipeline, residues 1-154 | unmapped |
| EV-MDDB-A00B2 MDDB | md | trajectory: 10 ns | in silico · 26.85 °C MoDEL 1DSW · start 1DSW; Amber Parm99 | unmapped |
| EV-SMASH-SMFS-000734 SMASH-BIO | force_spectroscopy | study_record | in vitro Direct observation of prion-like propagation of protein misfolding templated by pathogenic mutants. · Superoxide dismutase 1; optical tweezers; experiment class: receptor_ligand_adhesion, unfolding_protein | unmapped |
| EV-SMASH-SMFS-003309 SMASH-BIO | force_spectroscopy | study_record | in vitro Soft Vibrational Modes Predict Breaking Events during Force-Induced Protein Unfolding. · Superoxide dismutase 1; force spectroscopy unspecified; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-003637 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7 Partially native intermediates mediate misfolding of SOD1 in single-molecule folding trajectories. · Superoxide dismutase 1; optical tweezers; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-003767 SMASH-BIO | force_spectroscopy | study_record | in vitro The unfolding mechanism of monomeric mutant SOD1 by simulated force spectroscopy. · Superoxide dismutase 1; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-003825 SMASH-BIO | force_spectroscopy | study_record | in vitro As Simple As Possible, but Not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy. · Superoxide dismutase 1; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-004108 SMASH-BIO | force_spectroscopy | study_record | in vitro · pH 7.8 A Multifaceted Study of Scedosporium boydii Cell Wall Changes during Germination and Identification of GPI-Anchored Proteins. · Superoxide dismutase 1; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
| EV-SMASH-SMFS-004459 SMASH-BIO | force_spectroscopy | study_record | in vitro Altered thiol chemistry in human amyotrophic lateral sclerosis-linked mutants of superoxide dismutase 1. · Superoxide dismutase 1; afm smfs; experiment class: unfolding_protein | unmapped |
| EV-SMASH-SMFS-006160 SMASH-BIO | force_spectroscopy | study_record | in vitro Protonated nanoparticle surface governing ligand tethering and cellular targeting. · Superoxide dismutase 1; afm smfs; experiment class: receptor_ligand_adhesion | unmapped |
Conflicts
No conflicts found among comparable evidence.
191 evidence items could not be compared: they lack a comparable observable type, a value, or an uncertainty. Absence of a conflict here is not agreement.