{
  "conflicts": [],
  "coverage": {
    "cells": {},
    "data_levels": {},
    "single_method_states": [],
    "states": [],
    "techniques": [
      "xray",
      "nmr_shifts",
      "force_spectroscopy",
      "af_prediction"
    ],
    "unmapped_evidence": 15
  },
  "curation": {
    "as_of": "",
    "curator": "none",
    "file": "",
    "status": "uncurated"
  },
  "evidence": [
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Fermitin family homolog 2,Integrin beta-1 (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5XQ0",
      "evidence_id": "EV-PDB-5XQ0-1",
      "mappings": [],
      "molecule_id": "P09055",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.75
      },
      "provenance": {
        "deposit_id": "5XQ0",
        "doi": "10.1073/pnas.1703064114",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5XQ0"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Structural basis of kindlin-mediated integrin recognition and activation"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Integrin beta-1 (chains C)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8TEC",
      "evidence_id": "EV-PDB-8TEC-2",
      "mappings": [],
      "molecule_id": "P09055",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.04
      },
      "provenance": {
        "deposit_id": "8TEC",
        "doi": "10.1016/j.isci.2024.110129",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8TEC"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of Kindlin2 in complex with acylated beta1 integrin peptide"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Integrin beta-1 (chains C,D)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8TEE",
      "evidence_id": "EV-PDB-8TEE-2",
      "mappings": [],
      "molecule_id": "P09055",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.49
      },
      "provenance": {
        "deposit_id": "8TEE",
        "doi": "10.1016/j.isci.2024.110129",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8TEE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of Kindlin2 in complex with K794Q mutated beta1 integrin"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "From the first sample condition list of the entry.",
        "ph": 6.1,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "BMRB data: 15N chemical shifts, 1H chemical shifts",
        "labels": []
      },
      "data_format": "NMR-STAR",
      "data_level": "processed",
      "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=16159",
      "evidence_id": "EV-BMRB-16159",
      "mappings": [],
      "molecule_id": "P09055",
      "observable": {
        "type": "chemical_shift",
        "uncertainty": null,
        "unit": null,
        "value": null
      },
      "provenance": {
        "deposit_id": "bmr16159",
        "doi": "10.13018/BMR16159",
        "licence": "CC0 1.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "BMRB",
        "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=16159"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "nmr_shifts",
      "title": "Beta1A Integrin Cytoplasmic Tail 1H and 15N Chemical Shift Assignments"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_silico",
        "ions": [],
        "ligands": [],
        "notes": "Computed prediction; no experimental conditions.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "AlphaFold Monomer v2.0 pipeline, residues 1-798",
        "labels": []
      },
      "data_format": "mmCIF, PAE JSON",
      "data_level": "processed",
      "data_link": "https://alphafold.ebi.ac.uk/entry/P09055",
      "evidence_id": "EV-AFDB-AF-P09055-F1",
      "mappings": [],
      "molecule_id": "P09055",
      "observable": {
        "type": "plddt",
        "uncertainty": null,
        "unit": "pLDDT",
        "value": 85.94
      },
      "provenance": {
        "deposit_id": "AF-P09055-F1",
        "doi": null,
        "licence": "CC BY 4.0",
        "retrieved": "2026-10-19",
        "source": "AlphaFold DB",
        "url": "https://alphafold.ebi.ac.uk/entry/P09055"
      },
      "reader": null,
      "source_kind": "computed",
      "technique": "af_prediction",
      "title": "AlphaFold DB prediction AF-P09055-F1"
    }
  ],
  "models": [],
  "molecule": {
    "components": [],
    "domains": [
      {
        "end": 76,
        "name": "PSI",
        "start": 26
      },
      {
        "end": 378,
        "name": "VWFA",
        "start": 140
      },
      {
        "end": 501,
        "name": "I-EGF 1",
        "start": 466
      },
      {
        "end": 554,
        "name": "I-EGF 2",
        "start": 502
      },
      {
        "end": 591,
        "name": "I-EGF 3",
        "start": 555
      },
      {
        "end": 631,
        "name": "I-EGF 4",
        "start": 592
      }
    ],
    "gene": "Itgb1",
    "identifiers": {
      "genbank": null,
      "isoform": null,
      "nakb": null,
      "pdb": [],
      "rfam": null,
      "rnacentral": null,
      "uniprot": "P09055"
    },
    "ligands": [
      "Ca(2+)",
      "Mg(2+)"
    ],
    "modifications": [
      {
        "kind": "ptm",
        "name": "Phosphothreonine",
        "position": 777,
        "source": "UniProtKB"
      },
      {
        "kind": "ptm",
        "name": "Phosphotyrosine",
        "position": 783,
        "source": "UniProtKB"
      },
      {
        "kind": "ptm",
        "name": "Phosphoserine",
        "position": 785,
        "source": "UniProtKB"
      },
      {
        "kind": "ptm",
        "name": "Phosphothreonine",
        "position": 789,
        "source": "UniProtKB"
      },
      {
        "kind": "ptm",
        "name": "N6-acetyllysine; alternate",
        "position": 794,
        "source": "UniProtKB"
      }
    ],
    "molecule_id": "P09055",
    "molecule_type": "protein",
    "name": "Integrin beta-1",
    "organism": {
      "name": "Mus musculus",
      "taxon_id": 10090
    },
    "provenance": {
      "deposit_id": "P09055",
      "doi": null,
      "licence": "CC BY 4.0 (UniProt)",
      "retrieved": "2026-10-19",
      "source": "UniProtKB",
      "url": "https://www.uniprot.org/uniprotkb/P09055/entry"
    },
    "sequence": "MNLQLVSWIGLISLICSVFGQTDKNRCLKANAKSCGECIQAGPNCGWCTNTTFLQEGMPTSARCDDLEALKKKGCQPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLLLKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTDRGEFFNELVGQQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITANKCPNKESETIKIKPLGFTEEVEVVLQFICKCNCQSHGIPASPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCRCRVCECYPNYTGSACDCSLDTGPCLASNGQICNGRGICECGACKCTDPKFQGPTCETCQTCLGVCAEHKECVQCRAFNKGEKKDTCAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYSVNGNNEAIVHVVETPDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK",
    "sequence_length": 798
  },
  "molecule_id": "P09055",
  "states": [],
  "transitions": []
}