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oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1R9S", "evidence_id": "EV-PDB-1R9S-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.25 }, "provenance": { "deposit_id": "1R9S", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1R9S" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; 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oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWA", "evidence_id": "EV-PDB-1TWA-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "1TWA", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWA" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with ATP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GTP", "MN", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWC", "evidence_id": "EV-PDB-1TWC-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0 }, "provenance": { "deposit_id": "1TWC", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWC" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with GTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MN", "UTP", "ZN" ], "notes": "Entry-level ligand list; 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oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWG", "evidence_id": "EV-PDB-1TWG-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "1TWG", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWG" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with CTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MN", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWH", "evidence_id": "EV-PDB-1TWH-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "1TWH", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWH" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with 2'dATP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WCM", "evidence_id": "EV-PDB-1WCM-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "1WCM", "doi": "10.1074/JBC.M413038200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WCM" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y1V", "evidence_id": "EV-PDB-1Y1V-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "1Y1V", "doi": "10.1016/j.molcel.2004.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y1V" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Refined RNA Polymerase II-TFIIS complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y1W", "evidence_id": "EV-PDB-1Y1W-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "1Y1W", "doi": "10.1016/j.molcel.2004.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y1W" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA Polymerase II elongation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "G2P", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y77", "evidence_id": "EV-PDB-1Y77-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5 }, "provenance": { "deposit_id": "1Y77", "doi": "10.1016/j.molcel.2004.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y77" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "DNH", "MG", "PT", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/24QP", "evidence_id": "EV-PDB-24QP-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.73 }, "provenance": { "deposit_id": "24QP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/24QP" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with an oxaliplatin-ICL lesion at +7 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "DNH", "MG", "PT", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/24QR", "evidence_id": "EV-PDB-24QR-12", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67 }, "provenance": { "deposit_id": "24QR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/24QR" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with an oxaliplatin-ICL lesion at +2 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/24QS", "evidence_id": "EV-PDB-24QS-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74 }, "provenance": { "deposit_id": "24QS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/24QS" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast post-translocation state Pol II in complex with a cisplatin-ICL lesion at +2 position in the second ICL DNA sequence." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/24QT", "evidence_id": "EV-PDB-24QT-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96 }, "provenance": { "deposit_id": "24QT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/24QT" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast pre-translocation state Pol II in complex with a cisplatin-ICL lesion at +2 position in the second ICL DNA sequence." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GTP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/29RF", "evidence_id": "EV-PDB-29RF-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02 }, "provenance": { "deposit_id": "29RF", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/29RF" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-III" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2B63", "evidence_id": "EV-PDB-2B63-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "2B63", "doi": "10.1038/nsmb1032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2B63" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA Polymerase II-RNA inhibitor complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2B8K", "evidence_id": "EV-PDB-2B8K-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.15 }, "provenance": { "deposit_id": "2B8K", "doi": "10.1016/j.str.2006.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2B8K" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "12-subunit RNA Polymerase II" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GTP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2E2H", "evidence_id": "EV-PDB-2E2H-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95 }, "provenance": { "deposit_id": "2E2H", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2E2H" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex at 5 mM Mg2+ with GTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "DGT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2E2I", "evidence_id": "EV-PDB-2E2I-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41 }, "provenance": { "deposit_id": "2E2I", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2E2I" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A,M)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JA7", "evidence_id": "EV-PDB-2JA7-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "2JA7", "doi": "10.1126/SCIENCE.1135400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JA7" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "CPD lesion containing RNA Polymerase II elongation complex C" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JA8", "evidence_id": "EV-PDB-2JA8-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "2JA8", "doi": "10.1126/SCIENCE.1135400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JA8" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "CPD lesion containing RNA Polymerase II elongation complex D" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85 }, "construct": { "description": "DNA-directed RNA polymerase (chains B)", "labels": [] }, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2L0I", "evidence_id": "EV-PDB-2L0I-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "structure", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "2L0I", "doi": "10.1038/nsmb.1893", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2L0I" }, "reader": null, "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains B)", "labels": [] }, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LO6", "evidence_id": "EV-PDB-2LO6-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "structure", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "2LO6", "doi": "10.1101/gad.192781.112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LO6" }, "reader": null, "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of Nrd1 CID bound to phosphorylated RNAP II CTD" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "DUT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NVQ", "evidence_id": "EV-PDB-2NVQ-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9 }, "provenance": { "deposit_id": "2NVQ", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NVQ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Elongation Complex in 150 mM Mg+2 with 2'dUTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "G2P", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NVT", "evidence_id": "EV-PDB-2NVT-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36 }, "provenance": { "deposit_id": "2NVT", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NVT" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "DUT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NVX", "evidence_id": "EV-PDB-2NVX-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "2NVX", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NVX" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MN", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NVY", "evidence_id": "EV-PDB-2NVY-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "2NVY", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NVY" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II form II in 150 mM Mn+2" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2R7Z", "evidence_id": "EV-PDB-2R7Z-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "2R7Z", "doi": "10.1038/nsmb1314", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2R7Z" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Cisplatin lesion containing RNA polymerase II elongation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2R92", "evidence_id": "EV-PDB-2R92-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "2R92", "doi": "10.1038/nature06290", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2R92" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Elongation complex of RNA polymerase II with artificial RdRP scaffold" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2R93", "evidence_id": "EV-PDB-2R93-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "2R93", "doi": "10.1038/nature06290", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2R93" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2VUM", "evidence_id": "EV-PDB-2VUM-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "2VUM", "doi": "10.1038/NSMB.1458", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2VUM" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Alpha-amanitin inhibited complete RNA polymerase II elongation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "UTP", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2YU9", "evidence_id": "EV-PDB-2YU9-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "2YU9", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2YU9" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex in 150 mm MG+2 with UTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/30ES", "evidence_id": "EV-PDB-30ES-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.54 }, "provenance": { "deposit_id": "30ES", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/30ES" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State V (TL-closed), in the presence of substrate ATP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/36RS", "evidence_id": "EV-PDB-36RS-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.75 }, "provenance": { "deposit_id": "36RS", "doi": "10.1016/j.jbc.2026.113389", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/36RS" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Saccharomyces cerevisiae RNA polymerase II without stalk (no Rpb4/Rpb7)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/30EP", "evidence_id": "EV-PDB-30EP-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55 }, "provenance": { "deposit_id": "30EP", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/30EP" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State III (TL-open), in the presence of substrate ATP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "UTP", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NVZ", "evidence_id": "EV-PDB-2NVZ-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3 }, "provenance": { "deposit_id": "2NVZ", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NVZ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II elongation complex with UTP, updated 11/2006" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JA6", "evidence_id": "EV-PDB-2JA6-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "2JA6", "doi": "10.1126/science.1135400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JA6" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "CPD lesion containing RNA Polymerase II elongation complex B" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JA5", "evidence_id": "EV-PDB-2JA5-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "2JA5", "doi": "10.1126/SCIENCE.1135400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JA5" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "CPD lesion containing RNA Polymerase II elongation complex A" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "G2P", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2E2J", "evidence_id": "EV-PDB-2E2J-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "2E2J", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2E2J" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y1Y", "evidence_id": "EV-PDB-1Y1Y-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "1Y1Y", "doi": "10.1016/j.molcel.2004.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y1Y" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II-TFIIS-DNA/RNA complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NT9", "evidence_id": "EV-PDB-1NT9-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2 }, "provenance": { "deposit_id": "1NT9", "doi": "10.1073/pnas.1030608100", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NT9" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete 12-subunit RNA polymerase II" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NIK", "evidence_id": "EV-PDB-1NIK-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1 }, "provenance": { "deposit_id": "1NIK", "doi": "10.1073/pnas.1130601100", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NIK" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Wild Type RNA Polymerase II" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MN", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1I50", "evidence_id": "EV-PDB-1I50-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8 }, "provenance": { "deposit_id": "1I50", "doi": "10.1126/science.1059493", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1I50" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FKI", "evidence_id": "EV-PDB-3FKI-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88 }, "provenance": { "deposit_id": "3FKI", "doi": "10.1074/jbc.M809199200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FKI" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "12-Subunit RNA Polymerase II Refined with Zn-SAD data" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTK", "evidence_id": "EV-PDB-3GTK-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "3GTK", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTK" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Backtracked RNA polymerase II complex with 18mer RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -180.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K7A", "evidence_id": "EV-PDB-3K7A-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "3K7A", "doi": "10.1126/science.1182015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K7A" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an RNA polymerase II-TFIIB complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ACT", "EPE", "MG", "PGE", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PO3", "evidence_id": "EV-PDB-3PO3-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "3PO3", "doi": "10.1038/nature09785", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PO3" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Arrested RNA Polymerase II reactivation intermediate" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "G2P", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3J", "evidence_id": "EV-PDB-4A3J-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "4A3J", "doi": "10.1038/EMBOJ.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3J" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3L", "evidence_id": "EV-PDB-4A3L-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "4A3L", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3L" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3K", "evidence_id": "EV-PDB-4A3K-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "4A3K", "doi": "10.1038/EMBOJ.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3K" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3I", "evidence_id": "EV-PDB-4A3I-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "4A3I", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3I" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II binary complex with DNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3G", "evidence_id": "EV-PDB-4A3G-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "4A3G", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3G" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3F", "evidence_id": "EV-PDB-4A3F-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "4A3F", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3F" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3E", "evidence_id": "EV-PDB-4A3E-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "4A3E", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3E" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3D", "evidence_id": "EV-PDB-4A3D-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "4A3D", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3D" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3C", "evidence_id": "EV-PDB-4A3C-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "4A3C", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3C" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3B", "evidence_id": "EV-PDB-4A3B-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "4A3B", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3B" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S2H", "evidence_id": "EV-PDB-3S2H-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "3S2H", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S2H" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 6-nt RNA containing a 2[prime]-iodo ATP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S2D", "evidence_id": "EV-PDB-3S2D-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "3S2D", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S2D" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 5-nt RNA containing a 5Br-U" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GTP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S1R", "evidence_id": "EV-PDB-3S1R-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "3S1R", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S1R" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with GTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S1Q", "evidence_id": "EV-PDB-3S1Q-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "3S1Q", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S1Q" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S1N", "evidence_id": "EV-PDB-3S1N-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1 }, "provenance": { "deposit_id": "3S1N", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S1N" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 2)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S1M", "evidence_id": "EV-PDB-3S1M-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13 }, "provenance": { "deposit_id": "3S1M", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S1M" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S17", "evidence_id": "EV-PDB-3S17-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "3S17", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S17" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 9-nt RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S16", "evidence_id": "EV-PDB-3S16-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.241 }, "provenance": { "deposit_id": "3S16", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S16" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with an 8-nt RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S15", "evidence_id": "EV-PDB-3S15-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "3S15", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S15" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 7-nt RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S14", "evidence_id": "EV-PDB-3S14-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85 }, "provenance": { "deposit_id": "3S14", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S14" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 6-nt RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RZO", "evidence_id": "EV-PDB-3RZO-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0 }, "provenance": { "deposit_id": "3RZO", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RZO" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 4-nt RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RZD", "evidence_id": "EV-PDB-3RZD-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "3RZD", "doi": "10.1126/science.1206629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RZD" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II Initiation Complex with a 5-nt RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3QT1", "evidence_id": "EV-PDB-3QT1-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3 }, "provenance": { "deposit_id": "3QT1", "doi": "10.1074/jbc.M111.222273", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3QT1" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II variant containing A Chimeric RPB9-C11 subunit" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ACT", "EPE", "MG", "PEG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PO2", "evidence_id": "EV-PDB-3PO2-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "3PO2", "doi": "10.1038/nature09785", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PO2" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Arrested RNA Polymerase II elongation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "C7P", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -196.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M4O", "evidence_id": "EV-PDB-3M4O-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.57 }, "provenance": { "deposit_id": "3M4O", "doi": "10.1073/pnas.1002565107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M4O" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex B" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "C7P", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -196.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M3Y", "evidence_id": "EV-PDB-3M3Y-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18 }, "provenance": { "deposit_id": "3M3Y", "doi": "10.1073/pnas.1002565107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M3Y" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex C" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K1F", "evidence_id": "EV-PDB-3K1F-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3 }, "provenance": { "deposit_id": "3K1F", "doi": "10.1038/nature08548", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K1F" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of RNA Polymerase II in complex with TFIIB" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3J1N", "evidence_id": "EV-PDB-3J1N-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 16.0 }, "provenance": { "deposit_id": "3J1N", "doi": "10.1016/j.str.2012.02.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3J1N" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3J0K", "evidence_id": "EV-PDB-3J0K-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 36.0 }, "provenance": { "deposit_id": "3J0K", "doi": "10.1371/journal.pbio.1000603", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3J0K" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Orientation of RNA polymerase II within the human VP16-Mediator-pol II-TFIIF assembly" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3I4N", "evidence_id": "EV-PDB-3I4N-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9 }, "provenance": { "deposit_id": "3I4N", "doi": "10.1074/jbc.M109.022764", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3I4N" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "8-oxoguanine containing RNA polymerase II elongation complex E" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3I4M", "evidence_id": "EV-PDB-3I4M-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "3I4M", "doi": "10.1074/jbc.M109.022764", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3I4M" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "8-oxoguanine containing RNA polymerase II elongation complex D" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HOZ", "evidence_id": "EV-PDB-3HOZ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65 }, "provenance": { "deposit_id": "3HOZ", "doi": "10.1016/j.molcel.2009.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HOZ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HOY", "evidence_id": "EV-PDB-3HOY-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "3HOY", "doi": "10.1016/j.molcel.2009.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HOY" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA polymerase II elongation complex VI" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HOX", "evidence_id": "EV-PDB-3HOX-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65 }, "provenance": { "deposit_id": "3HOX", "doi": "10.1016/j.molcel.2009.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HOX" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA polymerase II elongation complex V" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HOW", "evidence_id": "EV-PDB-3HOW-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "3HOW", "doi": "10.1016/j.molcel.2009.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HOW" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HOV", "evidence_id": "EV-PDB-3HOV-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "3HOV", "doi": "10.1016/j.molcel.2009.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HOV" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA polymerase II elongation complex II" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A,M)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HOU", "evidence_id": "EV-PDB-3HOU-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "3HOU", "doi": "10.1016/j.molcel.2009.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HOU" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complete RNA polymerase II elongation complex I with a T-U mismatch" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3H3V", "evidence_id": "EV-PDB-3H3V-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "3H3V", "doi": "10.1074/jbc.M109.013847", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3H3V" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Yeast RNAP II containing poly(A)-signal sequence in the active site" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTQ", "evidence_id": "EV-PDB-3GTQ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "3GTQ", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTQ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Backtracked RNA polymerase II complex induced by damage" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTP", "evidence_id": "EV-PDB-3GTP-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9 }, "provenance": { "deposit_id": "3GTP", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTP" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Backtracked RNA polymerase II complex with 24mer RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTO", "evidence_id": "EV-PDB-3GTO-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "3GTO", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTO" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Backtracked RNA polymerase II complex with 15mer RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTM", "evidence_id": "EV-PDB-3GTM-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "3GTM", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTM" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Co-complex of Backtracked RNA polymerase II with TFIIS" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTL", "evidence_id": "EV-PDB-3GTL-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38 }, "provenance": { "deposit_id": "3GTL", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTL" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Backtracked RNA polymerase II complex with 13mer with G<>U mismatch" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTJ", "evidence_id": "EV-PDB-3GTJ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42 }, "provenance": { "deposit_id": "3GTJ", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTJ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Backtracked RNA polymerase II complex with 13mer RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GTG", "evidence_id": "EV-PDB-3GTG-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.78 }, "provenance": { "deposit_id": "3GTG", "doi": "10.1126/science.1168729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GTG" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Backtracked RNA polymerase II complex with 12mer RNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3CQZ", "evidence_id": "EV-PDB-3CQZ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8 }, "provenance": { "deposit_id": "3CQZ", "doi": "10.1016/J.MOLCEL.2008.04.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3CQZ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4V1N", "evidence_id": "EV-PDB-4V1N-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.8 }, "provenance": { "deposit_id": "4V1N", "doi": "10.1038/NATURE14229", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4V1N" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Architecture of the RNA polymerase II-Mediator core transcription initiation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4V1O", "evidence_id": "EV-PDB-4V1O-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 9.7 }, "provenance": { "deposit_id": "4V1O", "doi": "10.1038/NATURE14229", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4V1O" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Architecture of the RNA polymerase II-Mediator core transcription initiation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains k)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5SVA", "evidence_id": "EV-PDB-5SVA-37", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 15.3 }, "provenance": { "deposit_id": "5SVA", "doi": "10.1016/j.cell.2016.08.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5SVA" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-RNA Polymerase II Pre-Initiation Complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5SVA", "evidence_id": "EV-PDB-5SVA-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 15.3 }, "provenance": { "deposit_id": "5SVA", "doi": "10.1016/j.cell.2016.08.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5SVA" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-RNA Polymerase II Pre-Initiation Complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BQF", "evidence_id": "EV-PDB-6BQF-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35 }, "provenance": { "deposit_id": "6BQF", "doi": "10.1073/pnas.1722050115", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BQF" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Pol II elongation complex with 'dT-AP' at i+1, i-1 position" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O6C", "evidence_id": "EV-PDB-6O6C-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1 }, "provenance": { "deposit_id": "6O6C", "doi": "10.1016/j.jsb.2019.06.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O6C" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II elongation complex arrested at a CPD lesion" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "PO4" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Ser2/Ser5 phosphorylated peptide (chains E)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6NPW", "evidence_id": "EV-PDB-6NPW-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.486 }, "provenance": { "deposit_id": "6NPW", "doi": "10.1074/jbc.RA119.007697", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6NPW" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6I84", "evidence_id": "EV-PDB-6I84-7", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4 }, "provenance": { "deposit_id": "6I84", "doi": "10.1038/s41467-018-07870-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6I84" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of transcribing RNA polymerase II-nucleosome complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6GYM", "evidence_id": "EV-PDB-6GYM-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.7 }, "provenance": { "deposit_id": "6GYM", "doi": "10.1016/j.molcel.2018.10.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6GYM" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of a yeast closed complex with distorted DNA (CCdist)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6GYL", "evidence_id": "EV-PDB-6GYL-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8 }, "provenance": { "deposit_id": "6GYL", "doi": "10.1016/j.molcel.2018.10.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6GYL" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of a yeast closed complex with distorted DNA (core CCdist)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6GYK", "evidence_id": "EV-PDB-6GYK-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.1 }, "provenance": { "deposit_id": "6GYK", "doi": "10.1016/j.molcel.2018.10.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6GYK" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of a yeast closed complex (core CC1)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "2KH", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BM4", "evidence_id": "EV-PDB-6BM4-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.951 }, "provenance": { "deposit_id": "6BM4", "doi": "10.1073/pnas.1722050115", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BM4" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Pol II elongation complex with an abasic lesion at i-1 position,soaking UMPNPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BM2", "evidence_id": "EV-PDB-6BM2-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.403 }, "provenance": { "deposit_id": "6BM2", "doi": "10.1073/pnas.1722050115", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BM2" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Pol II elongation complex with an abasic lesion at i-1 position" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BLP", "evidence_id": "EV-PDB-6BLP-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.203 }, "provenance": { "deposit_id": "6BLP", "doi": "10.1073/pnas.1722050115", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BLP" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Pol II elongation complex with an abasic lesion at i+1 position, soaking AMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BLO", "evidence_id": "EV-PDB-6BLO-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.401 }, "provenance": { "deposit_id": "6BLO", "doi": "10.1073/pnas.1722050115", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BLO" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Pol II elongation complex with an abasic lesion at i+1 position" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "2KH", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W51", "evidence_id": "EV-PDB-5W51-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.404 }, "provenance": { "deposit_id": "5W51", "doi": "10.1021/jacs.7b06381", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W51" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W4U", "evidence_id": "EV-PDB-5W4U-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "5W4U", "doi": "10.1021/jacs.7b06381", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W4U" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Pol II elongation complex with an N6-methyladenine-containing template" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VVS", "evidence_id": "EV-PDB-5VVS-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.4 }, "provenance": { "deposit_id": "5VVS", "doi": "10.1038/nature24658", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VVS" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA pol II elongation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VVR", "evidence_id": "EV-PDB-5VVR-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.8 }, "provenance": { "deposit_id": "5VVR", "doi": "10.1038/nature24658", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VVR" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Ternary complex of RNA Pol II, transcription scaffold and Rad26" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "IPA" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VKO", "evidence_id": "EV-PDB-5VKO-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8 }, "provenance": { "deposit_id": "5VKO", "doi": "10.7554/eLife.28723", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VKO" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VKL", "evidence_id": "EV-PDB-5VKL-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.198 }, "provenance": { "deposit_id": "5VKL", "doi": "10.7554/eLife.28723", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VKL" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "SPT6 tSH2-RPB1 1476-1500 pS1493" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": 20.0 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5U5Q", "evidence_id": "EV-PDB-5U5Q-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "5U5Q", "doi": "10.1038/srep44628", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5U5Q" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "12 Subunit RNA Polymerase II at Room Temperature collected using SFX" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "AHW", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OT2", "evidence_id": "EV-PDB-5OT2-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "5OT2", "doi": "10.1073/pnas.1706592114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OT2" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex in the presence of 3d-Napht-A" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OQM", "evidence_id": "EV-PDB-5OQM-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.8 }, "provenance": { "deposit_id": "5OQM", "doi": "10.1038/nature24282", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OQM" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OQJ", "evidence_id": "EV-PDB-5OQJ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.7 }, "provenance": { "deposit_id": "5OQJ", "doi": "10.1038/nature24282", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OQJ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85 }, "construct": { "description": "THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER (chains B)", "labels": [] }, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5M9D", "evidence_id": "EV-PDB-5M9D-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "structure", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "5M9D", "doi": "10.1073/pnas.1712450114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5M9D" }, "reader": null, "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 19.85 }, "construct": { "description": "PRO-SER-TYR-SER-PRO-PTH-SER-PRO-SER-TYR-SER-PRO-THR-SER-PRO-SER (chains B)", "labels": [] }, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LVF", "evidence_id": "EV-PDB-5LVF-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "structure", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "5LVF", "doi": "10.15252/embr.201643723", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LVF" }, "reader": null, "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IP9", "evidence_id": "EV-PDB-5IP9-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9 }, "provenance": { "deposit_id": "5IP9", "doi": "10.1038/nature17990", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IP9" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of RNA Polymerase II-TFIIF complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IP7", "evidence_id": "EV-PDB-5IP7-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52 }, "provenance": { "deposit_id": "5IP7", "doi": "10.1038/nature17990", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IP7" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of RNA Polymerase II-Tfg1 peptide complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5FZ5", "evidence_id": "EV-PDB-5FZ5-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 8.8 }, "provenance": { "deposit_id": "5FZ5", "doi": "10.1038/NATURE17990", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5FZ5" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Transcription initiation complex structures elucidate DNA opening (CC)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5FYW", "evidence_id": "EV-PDB-5FYW-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.35 }, "provenance": { "deposit_id": "5FYW", "doi": "10.1038/NATURE17990", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5FYW" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Transcription initiation complex structures elucidate DNA opening (OC)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5FMF", "evidence_id": "EV-PDB-5FMF-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.0 }, "provenance": { "deposit_id": "5FMF", "doi": "10.1073/PNAS.1518255112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5FMF" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "the P-lobe of RNA polymerase II pre-initiation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C4X", "evidence_id": "EV-PDB-5C4X-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "5C4X", "doi": "10.1016/j.molcel.2015.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C4X" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C4J", "evidence_id": "EV-PDB-5C4J-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "5C4J", "doi": "10.1016/j.molcel.2015.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C4J" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C4A", "evidence_id": "EV-PDB-5C4A-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2 }, "provenance": { "deposit_id": "5C4A", "doi": "10.1016/j.molcel.2015.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C4A" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C44", "evidence_id": "EV-PDB-5C44-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95 }, "provenance": { "deposit_id": "5C44", "doi": "10.1016/j.molcel.2015.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C44" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C3E", "evidence_id": "EV-PDB-5C3E-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "5C3E", "doi": "10.1016/j.molcel.2015.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C3E" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "G2P", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Y7N", "evidence_id": "EV-PDB-4Y7N-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "4Y7N", "doi": "10.1038/nature14482", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Y7N" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "The Structure Insight into 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Y52", "evidence_id": "EV-PDB-4Y52-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "4Y52", "doi": "10.1038/nature14482", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Y52" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X6A", "evidence_id": "EV-PDB-4X6A-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.96 }, "provenance": { "deposit_id": "4X6A", "doi": "10.1073/pnas.1415186112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X6A" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of yeast RNA polymerase II encountering oxidative Cyclopurine DNA lesions" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X67", "evidence_id": "EV-PDB-4X67-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1 }, "provenance": { "deposit_id": "4X67", "doi": "10.1073/pnas.1415186112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X67" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4V1M", "evidence_id": "EV-PDB-4V1M-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.6 }, "provenance": { "deposit_id": "4V1M", "doi": "10.1038/NATURE14229", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4V1M" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Architecture of the RNA polymerase II-Mediator core transcription initiation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains H)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GWQ", "evidence_id": "EV-PDB-4GWQ-8", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5 }, "provenance": { "deposit_id": "4GWQ", "doi": "10.1073/pnas.1215241109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GWQ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "EPE", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BY7", "evidence_id": "EV-PDB-4BY7-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15 }, "provenance": { "deposit_id": "4BY7", "doi": "10.1073/pnas.1311010110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BY7" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "elongating RNA Polymerase II-Bye1 TLD complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BY1", "evidence_id": "EV-PDB-4BY1-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "4BY1", "doi": "10.1073/PNAS.1311010110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BY1" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BXZ", "evidence_id": "EV-PDB-4BXZ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8 }, "provenance": { "deposit_id": "4BXZ", "doi": "10.1073/PNAS.1311010110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BXZ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II-Bye1 complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BXX", "evidence_id": "EV-PDB-4BXX-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.28 }, "provenance": { "deposit_id": "4BXX", "doi": "10.1073/PNAS.1311010110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BXX" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Arrested RNA polymerase II-Bye1 complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BBS", "evidence_id": "EV-PDB-4BBS-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "4BBS", "doi": "10.1038/NATURE11715", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BBS" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of an initially transcribing RNA polymerase II-TFIIB complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BBR", "evidence_id": "EV-PDB-4BBR-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "4BBR", "doi": "10.1038/NATURE11715", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BBR" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of RNA polymerase II-TFIIB complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A93", "evidence_id": "EV-PDB-4A93-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "4A93", "doi": "10.1016/J.MOLCEL.2012.02.006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A93" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II elongation complex containing a CPD Lesion" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A3M", "evidence_id": "EV-PDB-4A3M-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9 }, "provenance": { "deposit_id": "4A3M", "doi": "10.1038/emboj.2011.396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A3M" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UPZ", "evidence_id": "EV-PDB-6UPZ-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1 }, "provenance": { "deposit_id": "6UPZ", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UPZ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UQ0", "evidence_id": "EV-PDB-6UQ0-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56 }, "provenance": { "deposit_id": "6UQ0", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UQ0" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 4" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UQ1", "evidence_id": "EV-PDB-6UQ1-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "6UQ1", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UQ1" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UQ3", "evidence_id": "EV-PDB-6UQ3-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47 }, "provenance": { "deposit_id": "6UQ3", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UQ3" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KED", "evidence_id": "EV-PDB-7KED-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "7KED", "doi": "10.1038/s41589-021-00817-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KED" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with unnatural base dTPT3" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "WCG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KEE", "evidence_id": "EV-PDB-7KEE-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45 }, "provenance": { "deposit_id": "7KEE", "doi": "10.1038/s41589-021-00817-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KEE" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "WC4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KEF", "evidence_id": "EV-PDB-7KEF-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.89 }, "provenance": { "deposit_id": "7KEF", "doi": "10.1038/s41589-021-00817-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KEF" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A,a)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MEI", "evidence_id": "EV-PDB-7MEI-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54 }, "provenance": { "deposit_id": "7MEI", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MEI" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Composite structure of EC+EC" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MK9", "evidence_id": "EV-PDB-7MK9-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54 }, "provenance": { "deposit_id": "7MK9", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MK9" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Complex structure of trailing EC of EC+EC (trailing EC-focused)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains a)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MKA", "evidence_id": "EV-PDB-7MKA-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54 }, "provenance": { "deposit_id": "7MKA", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MKA" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of EC+EC (leading EC-focused)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ML0", "evidence_id": "EV-PDB-7ML0-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0 }, "provenance": { "deposit_id": "7ML0", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ML0" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II pre-initiation complex (PIC1)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ML1", "evidence_id": "EV-PDB-7ML1-12", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "7ML1", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ML1" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II pre-initiation complex (PIC2)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ML2", "evidence_id": "EV-PDB-7ML2-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "7ML2", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ML2" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II pre-initiation complex (PIC3)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ML4", "evidence_id": "EV-PDB-7ML4-6", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1 }, "provenance": { "deposit_id": "7ML4", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ML4" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II initially transcribing complex (ITC)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NKX", "evidence_id": "EV-PDB-7NKX-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9 }, "provenance": { "deposit_id": "7NKX", "doi": "10.1038/s41594-021-00578-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NKX" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II-Spt4/5-nucleosome-Chd1 structure" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NKY", "evidence_id": "EV-PDB-7NKY-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "7NKY", "doi": "10.1038/s41594-021-00578-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NKY" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA Polymerase II-Spt4/5-nucleosome-FACT structure" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O4I", "evidence_id": "EV-PDB-7O4I-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "7O4I", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O4I" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O4K", "evidence_id": "EV-PDB-7O4K-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "7O4K", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O4K" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast TFIIH in the contracted state within the pre-initiation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O4L", "evidence_id": "EV-PDB-7O4L-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "7O4L", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O4L" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast TFIIH in the expanded state within the pre-initiation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O72", "evidence_id": "EV-PDB-7O72-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "7O72", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O72" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O73", "evidence_id": "EV-PDB-7O73-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "7O73", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O73" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O75", "evidence_id": "EV-PDB-7O75-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "7O75", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O75" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "5N0", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RIM", "evidence_id": "EV-PDB-7RIM-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9 }, "provenance": { "deposit_id": "7RIM", "doi": "10.1073/pnas.2114065119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RIM" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "5N0", "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RIP", "evidence_id": "EV-PDB-7RIP-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "7RIP", "doi": "10.1073/pnas.2114065119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RIP" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 1 soaked with CTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RIQ", "evidence_id": "EV-PDB-7RIQ-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0 }, "provenance": { "deposit_id": "7RIQ", "doi": "10.1073/pnas.2114065119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RIQ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex scaffold 1 without polyamide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RIW", "evidence_id": "EV-PDB-7RIW-3", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "7RIW", "doi": "10.1073/pnas.2114065119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RIW" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex scaffold 2, without polyamide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "5N0", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RIX", "evidence_id": "EV-PDB-7RIX-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "7RIX", "doi": "10.1073/pnas.2114065119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RIX" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "5N0", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RIY", "evidence_id": "EV-PDB-7RIY-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "7RIY", "doi": "10.1073/pnas.2114065119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RIY" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with hairpin polyamide Py-Im 1, scaffold 2 soaked with UTP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UI9", "evidence_id": "EV-PDB-7UI9-22", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "7UI9", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UI9" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Core Mediator-PICearly (Copy A)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains z)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UI9", "evidence_id": "EV-PDB-7UI9-21", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "7UI9", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UI9" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Core Mediator-PICearly (Copy A)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A,z)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UIF", "evidence_id": "EV-PDB-7UIF-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6 }, "provenance": { "deposit_id": "7UIF", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UIF" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-PIC Early (Core B)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains z)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UIG", "evidence_id": "EV-PDB-7UIG-17", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3 }, "provenance": { "deposit_id": "7UIG", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UIG" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-PIC Early (Mediator A)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ALA", "ASP", "THR", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UIO", "evidence_id": "EV-PDB-7UIO-23", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "7UIO", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UIO" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-PIC Early (Composite Model)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ALA", "ASP", "THR", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains Az,Bz)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UIO", "evidence_id": "EV-PDB-7UIO-22", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3 }, "provenance": { "deposit_id": "7UIO", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UIO" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-PIC Early (Composite Model)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZSB", "evidence_id": "EV-PDB-7ZSB-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.6 }, "provenance": { "deposit_id": "7ZSB", "doi": "10.1038/s41594-022-00865-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZSB" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CEN", "evidence_id": "EV-PDB-8CEN-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0 }, "provenance": { "deposit_id": "8CEN", "doi": "10.1073/pnas.2220542120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CEN" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with core Mediator" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CEO", "evidence_id": "EV-PDB-8CEO-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "8CEO", "doi": "10.1073/pnas.2220542120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CEO" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JCH", "evidence_id": "EV-PDB-8JCH-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7 }, "provenance": { "deposit_id": "8JCH", "doi": "10.1038/s41586-024-07240-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JCH" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 1 (Pol II Rat1-PTTC1)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVP", "evidence_id": "EV-PDB-8TVP-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "8TVP", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVP" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVS", "evidence_id": "EV-PDB-8TVS-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4 }, "provenance": { "deposit_id": "8TVS", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVS" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of backtracked Pol II in complex with Rad26" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVV", "evidence_id": "EV-PDB-8TVV-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "8TVV", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVV" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of backtracked Pol II" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVQ", "evidence_id": "EV-PDB-8TVQ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6 }, "provenance": { "deposit_id": "8TVQ", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVQ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TUG", "evidence_id": "EV-PDB-8TUG-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "8TUG", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TUG" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RAP", "evidence_id": "EV-PDB-8RAP-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3 }, "provenance": { "deposit_id": "8RAP", "doi": "10.1038/s41594-024-01409-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RAP" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Sen1-ADP.BeF3 bound RNA Polymerase II pre-termination complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RAM", "evidence_id": "EV-PDB-8RAM-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8 }, "provenance": { "deposit_id": "8RAM", "doi": "10.1038/s41594-024-01409-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RAM" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Sen1 bound RNA Polymerase II pre-termination complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K5P", "evidence_id": "EV-PDB-8K5P-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8 }, "provenance": { "deposit_id": "8K5P", "doi": "10.1038/s41586-024-07240-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K5P" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 2 (Pol II Rat1-PTTC2)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZSA", "evidence_id": "EV-PDB-7ZSA-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0 }, "provenance": { "deposit_id": "7ZSA", "doi": "10.1038/s41594-022-00865-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZSA" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZS9", "evidence_id": "EV-PDB-7ZS9-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1 }, "provenance": { "deposit_id": "7ZS9", "doi": "10.1038/s41594-022-00865-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZS9" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ADP", "BEF", "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O4J", "evidence_id": "EV-PDB-7O4J-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9 }, "provenance": { "deposit_id": "7O4J", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O4J" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex (consensus)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UQ2", "evidence_id": "EV-PDB-6UQ2-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2 }, "provenance": { "deposit_id": "6UQ2", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UQ2" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dG in state 1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UPY", "evidence_id": "EV-PDB-6UPY-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "6UPY", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UPY" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UPX", "evidence_id": "EV-PDB-6UPX-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "6UPX", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UPX" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5D", "evidence_id": "EV-PDB-9N5D-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35 }, "provenance": { "deposit_id": "9N5D", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5D" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, CMP added" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PDR", "evidence_id": "EV-PDB-9PDR-11", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84 }, "provenance": { "deposit_id": "9PDR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PDR" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of PIC-Med-SWI/SNF-Nucleosome" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB4", "evidence_id": "EV-PDB-9SB4-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12 }, "provenance": { "deposit_id": "9SB4", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB4" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-D" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB3", "evidence_id": "EV-PDB-9SB3-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05 }, "provenance": { "deposit_id": "9SB3", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB3" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-C" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB2", "evidence_id": "EV-PDB-9SB2-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09 }, "provenance": { "deposit_id": "9SB2", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB2" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-B" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB1", "evidence_id": "EV-PDB-9SB1-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98 }, "provenance": { "deposit_id": "9SB1", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB1" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-A" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "PPV", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB0", "evidence_id": "EV-PDB-9SB0-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04 }, "provenance": { "deposit_id": "9SB0", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB0" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VI" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SAZ", "evidence_id": "EV-PDB-9SAZ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31 }, "provenance": { "deposit_id": "9SAZ", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SAZ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex apo-state-II" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SAY", "evidence_id": "EV-PDB-9SAY-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44 }, "provenance": { "deposit_id": "9SAY", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SAY" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex apo-state-I" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "DPO", "K", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RYB", "evidence_id": "EV-PDB-9RYB-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33 }, "provenance": { "deposit_id": "9RYB", "doi": "10.1016/j.molcel.2026.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RYB" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis state" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "K", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QEB", "evidence_id": "EV-PDB-9QEB-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26 }, "provenance": { "deposit_id": "9QEB", "doi": "10.1016/j.molcel.2026.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QEB" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of transcribing RNA polymerase II elongation complex" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "8GT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVX", "evidence_id": "EV-PDB-9PVX-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39 }, "provenance": { "deposit_id": "9PVX", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVX" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dA at +1 site, 8-oxo-GTP bound in E-site." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "POP", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVW", "evidence_id": "EV-PDB-9PVW-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56 }, "provenance": { "deposit_id": "9PVW", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVW" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dA at +1 site, 8-oxo-GMP added in Syn-conformation" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "8GT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVV", "evidence_id": "EV-PDB-9PVV-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48 }, "provenance": { "deposit_id": "9PVV", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVV" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dC at +1 site, 8-oxo-GTP bound in A-site." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVU", "evidence_id": "EV-PDB-9PVU-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31 }, "provenance": { "deposit_id": "9PVU", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVU" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dC at +1 site, 8-oxo-GMP added." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PDK", "evidence_id": "EV-PDB-9PDK-11", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8 }, "provenance": { "deposit_id": "9PDK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PDK" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of closed form of PIC-Med-SWI/SNF" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PDJ", "evidence_id": "EV-PDB-9PDJ-11", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8 }, "provenance": { "deposit_id": "9PDJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PDJ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of open form of PIC-Med-SWI/SNF" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PC8", "evidence_id": "EV-PDB-9PC8-7", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "9PC8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PC8" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Core Mediator of PIC-Med-SWI/SNF" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PC7", "evidence_id": "EV-PDB-9PC7-15", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "9PC7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PC7" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Core Mediator of PIC-Med-SWI/SNF-Nucleosome" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PBZ", "evidence_id": "EV-PDB-9PBZ-12", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "9PBZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PBZ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "PolII/TFIIF of PIC-Med-SWI/SNF-Nucleosome" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PBD", "evidence_id": "EV-PDB-9PBD-11", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9 }, "provenance": { "deposit_id": "9PBD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PBD" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "PolII/TFIIF of PIC-Med-SWI/SNF" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5G", "evidence_id": "EV-PDB-9N5G-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15 }, "provenance": { "deposit_id": "9N5G", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5G" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, ATP in both A- and E-site" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5F", "evidence_id": "EV-PDB-9N5F-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "9N5F", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5F" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG in syn-conformation with added AMP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "APC", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5E", "evidence_id": "EV-PDB-9N5E-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75 }, "provenance": { "deposit_id": "9N5E", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5E" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, AMPCPP in E-site" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "2TM", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5C", "evidence_id": "EV-PDB-9N5C-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "9N5C", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5C" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, CMPCPP-bound" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5B", "evidence_id": "EV-PDB-9N5B-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1 }, "provenance": { "deposit_id": "9N5B", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5B" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex containing 8-oxoG at +1 site, apo form" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KDQ", "evidence_id": "EV-PDB-9KDQ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.63 }, "provenance": { "deposit_id": "9KDQ", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KDQ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "The structure of 3 ACTD bound to RNA polymerase II elongation complex with 4 CTG repeats." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KDO", "evidence_id": "EV-PDB-9KDO-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92 }, "provenance": { "deposit_id": "9KDO", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KDO" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "The structure of 2 ACTD bound to RNA polymerase II elongation complex with 3 CTG repeats" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KDN", "evidence_id": "EV-PDB-9KDN-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96 }, "provenance": { "deposit_id": "9KDN", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KDN" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "The structure of 1 ACTD bound to RNA polymerase II elongation complex with 2 CTG repeats." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KD9", "evidence_id": "EV-PDB-9KD9-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88 }, "provenance": { "deposit_id": "9KD9", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KD9" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "The structure of RNA polymerase II elongation complex paused at N-5 state by actinomycin D." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KD8", "evidence_id": "EV-PDB-9KD8-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.46 }, "provenance": { "deposit_id": "9KD8", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KD8" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "The structure of RNA polymerase II elongation complex paused at N-2 state by actinomycin D." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KD7", "evidence_id": "EV-PDB-9KD7-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09 }, "provenance": { "deposit_id": "9KD7", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KD7" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "The structure of RNA polymerase II elongation complex paused at N-1 state by actinomycin D." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K7F", "evidence_id": "EV-PDB-9K7F-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5 }, "provenance": { "deposit_id": "9K7F", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K7F" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II elongation complex apo structure." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JA1", "evidence_id": "EV-PDB-9JA1-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98 }, "provenance": { "deposit_id": "9JA1", "doi": "10.1038/s41467-024-53745-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JA1" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "The RNA polymerase II elongation complex from Saccharomyces cerevisiae" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BW0", "evidence_id": "EV-PDB-9BW0-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51 }, "provenance": { "deposit_id": "9BW0", "doi": "10.1073/pnas.2318527121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BW0" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II - No ATP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GOL", "MN", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BVT", "evidence_id": "EV-PDB-9BVT-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "9BVT", "doi": "10.1073/pnas.2318527121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BVT" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA Pol II - High Mn(+2) concentration" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UOT", "evidence_id": "EV-PDB-8UOT-8", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "8UOT", "doi": "10.1093/nar/gkae805", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UOT" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of PICdeltaTFIIK form1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UOQ", "evidence_id": "EV-PDB-8UOQ-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8 }, "provenance": { "deposit_id": "8UOQ", "doi": "10.1093/nar/gkae805", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UOQ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of PIC_delta_TFIIK form2" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UMI", "evidence_id": "EV-PDB-8UMI-8", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "8UMI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UMI" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "consensus map of PICdeltaTFIIK form1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "SF4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase subunit (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UMH", "evidence_id": "EV-PDB-8UMH-2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1 }, "provenance": { "deposit_id": "8UMH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UMH" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Consensus map of PICdeltaTFIIK form2" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "POP", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKU", "evidence_id": "EV-PDB-8UKU-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "8UKU", "doi": "10.1021/jacs.3c14476", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKU" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with Fapy-dG lesion with CMP added" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "POP", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKT", "evidence_id": "EV-PDB-8UKT-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "8UKT", "doi": "10.1021/jacs.3c14476", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKT" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with Fapy-dG lesion with AMP added" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CTP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKS", "evidence_id": "EV-PDB-8UKS-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4 }, "provenance": { "deposit_id": "8UKS", "doi": "10.1021/jacs.3c14476", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKS" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKR", "evidence_id": "EV-PDB-8UKR-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.78 }, "provenance": { "deposit_id": "8UKR", "doi": "10.1021/jacs.3c14476", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKR" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKQ", "evidence_id": "EV-PDB-8UKQ-4", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5 }, "provenance": { "deposit_id": "8UKQ", "doi": "10.1021/jacs.3c14476", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKQ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with Fapy-dG lesion in apo state" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "GOL", "MN", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8U9X", "evidence_id": "EV-PDB-8U9X-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05 }, "provenance": { "deposit_id": "8U9X", "doi": "10.1073/pnas.2318527121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8U9X" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "GOL", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8U9R", "evidence_id": "EV-PDB-8U9R-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34 }, "provenance": { "deposit_id": "8U9R", "doi": "10.1073/pnas.2318527121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8U9R" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVY", "evidence_id": "EV-PDB-8TVY-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1 }, "provenance": { "deposit_id": "8TVY", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVY" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVX", "evidence_id": "EV-PDB-8TVX-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7 }, "provenance": { "deposit_id": "8TVX", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVX" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD-stalled Pol II (Conformation 2)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVW", "evidence_id": "EV-PDB-8TVW-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6 }, "provenance": { "deposit_id": "8TVW", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVW" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD-stalled Pol II (conformation 1)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB5", "evidence_id": "EV-PDB-9SB5-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56 }, "provenance": { "deposit_id": "9SB5", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB5" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-II" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBL", "evidence_id": "EV-PDB-9SBL-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.28 }, "provenance": { "deposit_id": "9SBL", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBL" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBM", "evidence_id": "EV-PDB-9SBM-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.17 }, "provenance": { "deposit_id": "9SBM", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBM" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-2" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBP", "evidence_id": "EV-PDB-9SBP-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95 }, "provenance": { "deposit_id": "9SBP", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBP" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-5" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBQ", "evidence_id": "EV-PDB-9SBQ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88 }, "provenance": { "deposit_id": "9SBQ", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBQ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-6" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBR", "evidence_id": "EV-PDB-9SBR-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.96 }, "provenance": { "deposit_id": "9SBR", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBR" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-7" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBS", "evidence_id": "EV-PDB-9SBS-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85 }, "provenance": { "deposit_id": "9SBS", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBS" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-8" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBT", "evidence_id": "EV-PDB-9SBT-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85 }, "provenance": { "deposit_id": "9SBT", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBT" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-9" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBU", "evidence_id": "EV-PDB-9SBU-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.83 }, "provenance": { "deposit_id": "9SBU", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBU" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-10" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBW", "evidence_id": "EV-PDB-9SBW-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63 }, "provenance": { "deposit_id": "9SBW", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBW" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-12" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBX", "evidence_id": "EV-PDB-9SBX-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53 }, "provenance": { "deposit_id": "9SBX", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBX" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-13" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBY", "evidence_id": "EV-PDB-9SBY-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41 }, "provenance": { "deposit_id": "9SBY", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBY" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-14" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBZ", "evidence_id": "EV-PDB-9SBZ-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35 }, "provenance": { "deposit_id": "9SBZ", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBZ" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-15" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC1", "evidence_id": "EV-PDB-9SC1-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48 }, "provenance": { "deposit_id": "9SC1", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC1" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-17" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC4", "evidence_id": "EV-PDB-9SC4-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76 }, "provenance": { "deposit_id": "9SC4", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC4" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-20" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8R", "evidence_id": "EV-PDB-9W8R-12", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68 }, "provenance": { "deposit_id": "9W8R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8R" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a short control scaffold lacking cisplatin-ICL lesion." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8T", "evidence_id": "EV-PDB-9W8T-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56 }, "provenance": { "deposit_id": "9W8T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8T" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a cisplatin-induced inter-strand crosslink lesion at the +7 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8U", "evidence_id": "EV-PDB-9W8U-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61 }, "provenance": { "deposit_id": "9W8U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8U" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of pre-translocation state of yeast Pol II complexed with a cisplatin-induced inter-strand crosslink at the +2 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8V", "evidence_id": "EV-PDB-9W8V-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.23 }, "provenance": { "deposit_id": "9W8V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8V" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of post-translocation state of yeast Pol II complexed with a cisplatin-induced inter-strand crosslink at the +2 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8Y", "evidence_id": "EV-PDB-9W8Y-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08 }, "provenance": { "deposit_id": "9W8Y", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8Y" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink at the + 3 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8Z", "evidence_id": "EV-PDB-9W8Z-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03 }, "provenance": { "deposit_id": "9W8Z", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8Z" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink at the + 2 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WQ7", "evidence_id": "EV-PDB-9WQ7-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72 }, "provenance": { "deposit_id": "9WQ7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WQ7" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II-Elf1 complex containing a cisplatin-ICL lesion at +7 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WQ8", "evidence_id": "EV-PDB-9WQ8-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98 }, "provenance": { "deposit_id": "9WQ8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WQ8" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a longer scaffold containing a cisplatin-ICL lesion at +7 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WQ9", "evidence_id": "EV-PDB-9WQ9-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95 }, "provenance": { "deposit_id": "9WQ9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WQ9" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a longer control scaffold lacking cisplatin-ICL lesion." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZPL", "evidence_id": "EV-PDB-9ZPL-9", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75 }, "provenance": { "deposit_id": "9ZPL", "doi": "10.1016/j.jbc.2026.113389", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZPL" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the complete Saccharomyces cerevisiae RNA polymerase II in open clamp conformation" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZPK", "evidence_id": "EV-PDB-9ZPK-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31 }, "provenance": { "deposit_id": "9ZPK", "doi": "10.1016/j.jbc.2026.113389", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZPK" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the complete Saccharomyces cerevisiae RNA polymerase II in closed clamp conformation" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8X", "evidence_id": "EV-PDB-9W8X-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86 }, "provenance": { "deposit_id": "9W8X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8X" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink lesion at the +5 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CPT", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8W", "evidence_id": "EV-PDB-9W8W-12", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91 }, "provenance": { "deposit_id": "9W8W", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8W" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of backtracked yeast Pol II in complex with a cisplatin-induced inter-strand crosslink lesion at the +2 position." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "K", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SV6", "evidence_id": "EV-PDB-9SV6-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96 }, "provenance": { "deposit_id": "9SV6", "doi": "10.1016/j.molcel.2026.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SV6" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC3", "evidence_id": "EV-PDB-9SC3-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.68 }, "provenance": { "deposit_id": "9SC3", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC3" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-19" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC2", "evidence_id": "EV-PDB-9SC2-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53 }, "provenance": { "deposit_id": "9SC2", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC2" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-18" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC0", "evidence_id": "EV-PDB-9SC0-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31 }, "provenance": { "deposit_id": "9SC0", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC0" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-16" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBV", "evidence_id": "EV-PDB-9SBV-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73 }, "provenance": { "deposit_id": "9SBV", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBV" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-11" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBO", "evidence_id": "EV-PDB-9SBO-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.97 }, "provenance": { "deposit_id": "9SBO", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBO" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-4" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ATP", "MG", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": [] }, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBN", "evidence_id": "EV-PDB-9SBN-1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95 }, "provenance": { "deposit_id": "9SBN", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBN" }, "reader": null, "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-3" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85 }, "construct": { "description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": [] }, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17044", "evidence_id": "EV-BMRB-17044", "mappings": [], "molecule_id": "P04050", "observable": { "type": "chemical_shift", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "bmr17044", "doi": "10.13018/BMR17044", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17044" }, "reader": null, "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 19.85 }, "construct": { "description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": [] }, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34041", "evidence_id": "EV-BMRB-34041", "mappings": [], "molecule_id": "P04050", "observable": { "type": "chemical_shift", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "bmr34041", "doi": "10.13018/BMR34041", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34041" }, "reader": null, "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85 }, "construct": { "description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": [] }, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34058", "evidence_id": "EV-BMRB-34058", "mappings": [], "molecule_id": "P04050", "observable": { "type": "chemical_shift", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "bmr34058", "doi": "10.13018/BMR34058", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34058" }, "reader": null, "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide" }, { "conditions": { "applied_force_pn": null, "buffer": "25 mM KH2PO4, 300 mM KCl, 10 mM BME", "environment": "in_vitro", "ions": [], "ligands": [ "partner: Regulator of Ty1 transposition protein 103" ], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 21 nm.", "ph": 6.5, "salt_mM": null, "temperature_c": 4.0 }, "construct": { "description": "DNA-directed RNA polymerase II subunit RPB1 with Regulator of Ty1 transposition protein 103", "labels": [] }, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDCZ2/", "evidence_id": "EV-SASBDB-SASDCZ2", "mappings": [], "molecule_id": "P04050", "observable": { "type": "radius_of_gyration", "uncertainty": 0.02, "unit": "nm", "value": 5.294 }, "provenance": { "deposit_id": "SASDCZ2", "doi": "10.1073/pnas.1712450114", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDCZ2/" }, "reader": null, "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the RNAPII CTDsome with Rtt103." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "residues 1549-1716; evidence: sodium dodecyl sulfate polyacrylamide gel electrophoresis evidence used in manual assertion", "labels": [] }, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/28497792", "evidence_id": "EV-DISPROT-DP02527r003", "mappings": [], "molecule_id": "P04050", "observable": { "type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 168 }, "provenance": { "deposit_id": "DP02527r003", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527" }, "reader": null, "source_kind": "literature", "technique": "gel_electrophoresis", "title": "DisProt DP02527: disorder, residues 1549-1716" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "residues 1456-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": [] }, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/28300169", "evidence_id": "EV-DISPROT-DP02527r004", "mappings": [], "molecule_id": "P04050", "observable": { "type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 278 }, "provenance": { "deposit_id": "DP02527r004", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527" }, "reader": null, "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1456-1733" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "residues 1446-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": [] }, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26123024", "evidence_id": "EV-DISPROT-DP02527r005", "mappings": [], "molecule_id": "P04050", "observable": { "type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 288 }, "provenance": { "deposit_id": "DP02527r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527" }, "reader": null, "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1446-1733" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "residues 1446-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": [] }, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/21798951", "evidence_id": "EV-DISPROT-DP02527r006", "mappings": [], "molecule_id": "P04050", "observable": { "type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 288 }, "provenance": { "deposit_id": "DP02527r006", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527" }, "reader": null, "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1446-1733" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "residues 1455-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": [] }, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26186291", "evidence_id": "EV-DISPROT-DP02527r007", "mappings": [], "molecule_id": "P04050", "observable": { "type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 279 }, "provenance": { "deposit_id": "DP02527r007", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527" }, "reader": null, "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1455-1733" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null }, "construct": { "description": "AlphaFold Monomer v2.0 pipeline, residues 1-1733", "labels": [] }, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P04050", "evidence_id": "EV-AFDB-AF-P04050-F1", "mappings": [], "molecule_id": "P04050", "observable": { "type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 81.38 }, "provenance": { "deposit_id": "AF-P04050-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P04050" }, "reader": null, "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P04050-F1" } ], "models": [], "molecule": { "components": [], "domains": [], "gene": "RPO21", "identifiers": { "genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P04050" }, "ligands": [ "Mg(2+)", "Zn(2+)" ], "modifications": [ { "kind": "ptm", "name": "Phosphothreonine", "position": 1471, "source": "UniProtKB" } ], "molecule_id": "P04050", "molecule_type": "protein", "name": "DNA-directed RNA polymerase II subunit RPB1", "organism": { "name": "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "taxon_id": 559292 }, "provenance": { "deposit_id": "P04050", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04050/entry" }, "sequence": "MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGSNDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR", "sequence_length": 1733 }, "molecule_id": "P04050", "states": [], "transitions": [] }