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        "md": 0,
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    },
    "data_levels": {
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      "HEWL-unfolded": {
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        "nmr_shifts": "processed"
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    },
    "single_method_states": [],
    "states": [
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      "HEWL-fibril"
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    "techniques": [
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  "curation": {
    "as_of": "2026-10-19",
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    "file": "P00698.yaml",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": null
      },
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        "description": "HEN EGG WHITE LYSOZYME (chains A)",
        "labels": []
      },
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      "evidence_id": "EV-PDB-132L-1",
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        {
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          "who": "rule:hewl-structures-native"
        }
      ],
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        "type": "resolution",
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        "value": 1.8
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        "doi": "10.1021/bi00088a041",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "url": "https://www.rcsb.org/structure/132L"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "STRUCTURAL CONSEQUENCES OF REDUCTIVE METHYLATION OF LYSINE RESIDUES IN HEN EGG WHITE LYSOZYME: AN X-RAY ANALYSIS AT 1.8 ANGSTROMS RESOLUTION"
    },
    {
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        ],
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        "ph": 4.3,
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        "temperature_c": null
      },
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      "data_link": "https://www.rcsb.org/structure/193L",
      "evidence_id": "EV-PDB-193L-1",
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        {
          "confidence": "high",
          "justification": "Representative native structure; title and UniProt mapping checked against RCSB.",
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          "who": "curator:draft (unreviewed)"
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        "value": 1.33
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        "doi": "10.1107/S090744499501674X",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/193L"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE 1.33 A STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME"
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    {
      "conditions": {
        "applied_force_pn": null,
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      "data_link": "https://www.rcsb.org/structure/194L",
      "evidence_id": "EV-PDB-194L-1",
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          "confidence": "medium",
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        "url": "https://www.rcsb.org/structure/194L"
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      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE 1.40 A STRUCTURE OF SPACEHAB-01 HEN EGG WHITE LYSOZYME"
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    {
      "conditions": {
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        "buffer": null,
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 6.5,
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        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME (chains C)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1A2Y",
      "evidence_id": "EV-PDB-1A2Y-3",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 1.5
      },
      "provenance": {
        "deposit_id": "1A2Y",
        "doi": "10.1021/bi980148j",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1A2Y"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.48,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1AKI",
      "evidence_id": "EV-PDB-1AKI-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
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      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 1.5
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        "doi": null,
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1AKI"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE STRUCTURE OF THE ORTHORHOMBIC FORM OF HEN EGG-WHITE LYSOZYME AT 1.5 ANGSTROMS RESOLUTION"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 3.85
      },
      "construct": {
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      "data_format": "mmCIF + structure factors",
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      "data_link": "https://www.rcsb.org/structure/1AT5",
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      ],
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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      ],
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        ],
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      ],
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      },
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    },
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    },
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    },
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      "technique": "xray",
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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      "source_kind": "deposit",
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      },
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      },
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        "url": "https://www.rcsb.org/structure/1C10"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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      "source_kind": "deposit",
      "technique": "xray",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1B2K"
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      "source_kind": "deposit",
      "technique": "xray",
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        "temperature_c": null
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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      },
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      },
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      "source_kind": "deposit",
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        "temperature_c": 19.85
      },
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      "source_kind": "deposit",
      "technique": "xray",
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      "source_kind": "deposit",
      "technique": "xray",
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    },
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        "temperature_c": -163.15
      },
      "construct": {
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        "url": "https://www.rcsb.org/structure/1IEE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME AT 0.94 A FROM CRYSTALS GROWN BY THE COUNTER-DIFFUSION METHOD"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": null
      },
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      "source_kind": "deposit",
      "technique": "neutron",
      "title": "HYDROGEN AND HYDRATION OF HEN EGG-WHITE LYSOZYME DETERMINED BY NEUTRON DIFFRACTION"
    },
    {
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        "temperature_c": 22.85
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      "source_kind": "deposit",
      "technique": "xray",
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        "temperature_c": 22.85
      },
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        "temperature_c": -173.15
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        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1KIP"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1KIQ",
      "evidence_id": "EV-PDB-1KIQ-3",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1KIQ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "FV MUTANT Y(B 101)F (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME"
    },
    {
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        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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        "labels": []
      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "doi": "10.1021/bi961709e",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1KIR"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME"
    },
    {
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        "buffer": null,
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          "SCN"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 5.0,
        "salt_mM": null,
        "temperature_c": 9.85
      },
      "construct": {
        "description": "PROTEIN (LYSOZYME) (chains A,B)",
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "evidence_id": "EV-PDB-1LCN-1",
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        {
          "confidence": "medium",
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        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LCN"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Monoclinic hen egg white lysozyme, thiocyanate complex"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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      },
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        "doi": "10.1107/S0907444902007126",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJE"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
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          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
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      "data_link": "https://www.rcsb.org/structure/1LJF",
      "evidence_id": "EV-PDB-1LJF-1",
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        {
          "confidence": "medium",
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          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJF"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% SUCROSE"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
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      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1LJG",
      "evidence_id": "EV-PDB-1LJG-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "unit": "Å",
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      },
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJG"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 5% GLYCEROL"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
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          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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        {
          "confidence": "medium",
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        }
      ],
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      },
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 5% GLYCEROL"
    },
    {
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        "environment": "in_vitro",
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1LJI",
      "evidence_id": "EV-PDB-1LJI-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJI"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE 10% SORBITOL"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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        "ligands": [
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        "labels": []
      },
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      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1LJJ",
      "evidence_id": "EV-PDB-1LJJ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJJ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% TREHALOSE"
    },
    {
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        "buffer": null,
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 19.85
      },
      "construct": {
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      ],
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJK"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 15% TREHALOSE"
    },
    {
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        "buffer": null,
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
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        "temperature_c": 24.85
      },
      "construct": {
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      },
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          "who": "rule:hewl-structures-native"
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LKR"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "MONOCLINIC HEN EGG WHITE LYSOZYME IODIDE"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
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        "temperature_c": 19.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "evidence_id": "EV-PDB-1LJ4-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJ4"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
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          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "doi": "10.1107/S0907444902007126",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LJ3"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
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        "temperature_c": 21.85
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      },
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        {
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      "technique": "xray",
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      "technique": "xray",
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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        "temperature_c": 19.85
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      },
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        {
          "confidence": "medium",
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          "who": "rule:hewl-structures-native"
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        "temperature_c": 22.85
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      "source_kind": "deposit",
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        "temperature_c": 22.85
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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        "temperature_c": 19.85
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        "temperature_c": 24.85
      },
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      "evidence_id": "EV-PDB-1HER-1",
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    {
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        ],
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        "temperature_c": null
      },
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      "data_format": "mmCIF + structure factors",
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      "evidence_id": "EV-PDB-1LKS-1",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": null
      },
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      },
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      "data_link": "https://www.rcsb.org/structure/1LMA",
      "evidence_id": "EV-PDB-1LMA-1",
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      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "PROTEIN HYDRATION AND WATER STRUCTURE: X-RAY ANALYSIS OF A CLOSELY PACKED PROTEIN CRYSTAL WITH VERY LOW SOLVENT CONTENT"
    },
    {
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        "ligands": [
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
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        "temperature_c": 4.85
      },
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      },
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      "data_link": "https://www.rcsb.org/structure/1LPI",
      "evidence_id": "EV-PDB-1LPI-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LPI"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEW LYSOZYME: TRP...NA CATION-PI INTERACTION"
    },
    {
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        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
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      },
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      "data_level": "processed",
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        {
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LSA"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER"
    },
    {
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        "environment": "in_vitro",
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        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
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      },
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      "data_level": "processed",
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      "mappings": [
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          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
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      ],
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      },
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER"
    },
    {
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        "environment": "in_vitro",
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      },
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      "technique": "xray",
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      },
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      },
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        "url": "https://www.rcsb.org/structure/1LSM"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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      },
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        "url": "https://www.rcsb.org/structure/1LSN"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": null
      },
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        {
          "confidence": "medium",
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
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        "temperature_c": null
      },
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      },
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        {
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          "who": "rule:hewl-structures-native"
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 11.85
      },
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      },
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        {
          "confidence": "medium",
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          "who": "rule:hewl-structures-native"
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      ],
      "molecule_id": "P00698",
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      },
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        "doi": "10.1016/S0167-4838(98)00027-2",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LYO"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "CROSS-LINKED LYSOZYME CRYSTAL IN NEAT WATER"
    },
    {
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-RAY STRUCTURE OF A MONOCLINIC FORM OF HEN EGG-WHITE LYSOZYME CRYSTALLIZED AT 313K. COMPARISON OF TWO INDEPENDENT MOLECULES"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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      },
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      },
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          "confidence": "medium",
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      },
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LYZ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Real-space refinement of the structure of hen egg-white lysozyme"
    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -153.15
      },
      "construct": {
        "description": "PROTEIN (LYSOZYME) (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1LZ8",
      "evidence_id": "EV-PDB-1LZ8-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 1.53
      },
      "provenance": {
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        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LZ8"
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "LYSOZYME PHASED ON ANOMALOUS SIGNAL OF SULFURS AND CHLORINES"
    },
    {
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        "applied_force_pn": null,
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        "environment": "in_vitro",
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        "ligands": [
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          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
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        "temperature_c": -173.15
      },
      "construct": {
        "description": "PROTEIN (LYSOZYME) (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1LZ9",
      "evidence_id": "EV-PDB-1LZ9-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "ANOMALOUS SIGNAL OF SOLVENT BROMINES USED FOR PHASING OF LYSOZYME"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
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      },
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        {
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        }
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      },
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"
    },
    {
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        ],
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        "temperature_c": null
      },
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      },
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        {
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      ],
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
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      },
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        "doi": "10.1006/jmbi.1994.0139",
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": null
      },
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        {
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      ],
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"
    },
    {
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        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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        }
      ],
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      },
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "unit": "Å",
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      },
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LZH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE STRUCTURES OF THE MONOCLINIC AND ORTHORHOMBIC FORMS OF HEN EGG-WHITE LYSOZYME AT 6 ANGSTROMS RESOLUTION."
    },
    {
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          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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        {
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          "state_id": "HEWL-native",
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        "url": "https://www.rcsb.org/structure/1LZN"
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      "source_kind": "deposit",
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        "temperature_c": null
      },
      "construct": {
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      },
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        "source": "RCSB PDB",
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        "temperature_c": null
      },
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        "labels": []
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "temperature_c": -173.15
      },
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        "labels": []
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Para-Arsanilate Derivative of Hen Egg-White Lysozyme"
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    {
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        "temperature_c": null
      },
      "construct": {
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      },
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
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    },
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        "temperature_c": null
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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        ],
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        "temperature_c": null
      },
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        "labels": []
      },
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        }
      ],
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "SO4"
        ],
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        "temperature_c": -173.15
      },
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1PS5",
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        {
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          "state_id": "HEWL-native",
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        }
      ],
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      },
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "NA"
        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1QIO",
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        }
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1QIO"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE CAUSED BY INTENSE SYNCHROTRON RADIATION TO HEN EGG WHITE LYSOZYME"
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          "NA"
        ],
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        "temperature_c": 3.85
      },
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      },
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      "data_level": "processed",
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          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF KRYPTON (55 BAR)"
    },
    {
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        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
        "description": "LYSOZYME (chains A)",
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      },
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      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1RFP",
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        }
      ],
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        "url": "https://www.rcsb.org/structure/1RFP"
      },
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    {
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          "PO4"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1RJC"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "NA",
          "RU7"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/1T3P",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
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    },
    {
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        ],
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        "temperature_c": -173.15
      },
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      },
      "data_format": "mmCIF + structure factors",
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        }
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
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          "ACY"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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          "confidence": "medium",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
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        "url": "https://www.rcsb.org/structure/1RCM"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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        {
          "confidence": "medium",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "crystal structure analysis of an anti-lysozyme antibody"
    },
    {
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        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
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          "who": "rule:hewl-structures-native"
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1NDM"
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme"
    },
    {
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        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 6.4,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1MEL"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN VH ANTIBODY FRAGMENT IN COMPLEX WITH LYSOZYME"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "evidence_id": "EV-PDB-1LZA-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "deposit_id": "1LZA",
        "doi": "10.1006/jmbi.1994.0139",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/1LZA"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"
    },
    {
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      },
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        ],
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        "temperature_c": -173.15
      },
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      "title": "Effect of alcohols on protein hydration"
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        "temperature_c": null
      },
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      "source_kind": "deposit",
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    },
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      },
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        ],
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      "source_kind": "deposit",
      "technique": "xray",
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        "temperature_c": 19.85
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      },
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    {
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        ],
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        "temperature_c": -183.15
      },
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      },
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        "temperature_c": 21.85
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "temperature_c": -173.15
      },
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        "labels": []
      },
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        "url": "https://www.rcsb.org/structure/29MR"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2(D-p-FPhF)(O2CCH3)2(O2CO)]"
    },
    {
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          "NA",
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        "temperature_c": -173.15
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(D-o-TolF)(O2CCH3)3]"
    },
    {
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          "CL",
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        "temperature_c": -173.15
      },
      "construct": {
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(D-p-TolF)(O2CCH3)3]"
    },
    {
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        ],
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        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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      "technique": "xray",
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        ],
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        "temperature_c": -173.15
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      },
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      ],
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        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
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        ],
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        "temperature_c": -173.15
      },
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        ],
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      },
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          "HO",
          "NA"
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        "salt_mM": null,
        "temperature_c": -168.15
      },
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      },
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    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
      },
      "construct": {
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        "salt_mM": null,
        "temperature_c": 11.85
      },
      "construct": {
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      },
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        "temperature_c": 16.85
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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    },
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        ],
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        "temperature_c": 16.85
      },
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      },
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    },
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        ],
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        "temperature_c": 16.85
      },
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      },
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    {
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        ],
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        "temperature_c": -173.15
      },
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      },
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      "technique": "xray",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains Y)",
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      },
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      "data_link": "https://www.rcsb.org/structure/2DQD",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hyhel-10 FV mutant (Hy50f) complexed with hen egg lysozyme"
    },
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
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      },
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      },
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      },
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      "technique": "xray",
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        "temperature_c": -178.15
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        ],
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      },
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      },
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        "temperature_c": 3.85
      },
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        ],
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        "temperature_c": -263.15
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      },
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      },
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    {
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        "temperature_c": -173.15
      },
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      },
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        ],
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          "URE"
        ],
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      },
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        {
          "confidence": "medium",
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      },
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
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        "temperature_c": null
      },
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength"
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    {
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        "temperature_c": -173.15
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "mappings": [
        {
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        }
      ],
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      },
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      "source_kind": "deposit",
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          "SO4"
        ],
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      },
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      },
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        {
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        }
      ],
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      "source_kind": "deposit",
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        ],
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        "temperature_c": -173.15
      },
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      },
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
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    {
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        "salt_mM": null,
        "temperature_c": null
      },
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        "description": "HEN EGG WHITE LYSOZYME (chains Y)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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        }
      ],
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      },
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
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        {
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        }
      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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        "temperature_c": null
      },
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      },
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      "evidence_id": "EV-PDB-2LYZ-1",
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        {
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          "who": "rule:hewl-structures-native"
        }
      ],
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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        "labels": []
      },
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        {
          "confidence": "medium",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/2LZH"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        ],
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        "temperature_c": null
      },
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      },
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        "source": "RCSB PDB",
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      },
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      "technique": "xray",
      "title": "REFINEMENT OF TRICLINIC LYSOZYME. II. THE METHOD OF STEREOCHEMICALLY RESTRAINED LEAST-SQUARES"
    },
    {
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          "CMO",
          "MN",
          "NA",
          "TFS"
        ],
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        "ph": 4.4,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/2Q0M",
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        ],
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        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "data_link": "https://www.rcsb.org/structure/2W1M",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/2W1M"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 2.070 A WAVELENGTH with 2theta 30 degrees data"
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    {
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        ],
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        "temperature_c": -173.15
      },
      "construct": {
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          "confidence": "medium",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/2W1X"
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "The interdependence of wavelength, redundancy and dose in sulfur SAD experiments: 1.284 A wavelength 360 images data"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
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        "doi": "10.1107/S0907444908030503",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/2W1Y"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 1.540 A wavelength 180 images data"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
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        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme E35Q chitopentaose complex"
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    {
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          "NA"
        ],
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        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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          "confidence": "medium",
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        "temperature_c": -173.15
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      },
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        "temperature_c": null
      },
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      },
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        "temperature_c": -173.15
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
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        "temperature_c": -173.15
      },
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      },
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      },
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      },
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      ],
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        "salt_mM": null,
        "temperature_c": null
      },
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      },
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      "technique": "xray",
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        "temperature_c": -173.15
      },
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      },
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      "source_kind": "deposit",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": null
      },
      "construct": {
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      },
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        }
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    },
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        "temperature_c": -163.15
      },
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      },
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      "technique": "xray",
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    {
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        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
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        "temperature_c": 11.85
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 95% ACETONITRILE-WATER"
    },
    {
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        "buffer": null,
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          "NO3"
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        "temperature_c": -153.15
      },
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        {
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      "technique": "xray",
      "title": "REFINEMENT OF TRICLINIC LYSOZYME AT ATOMIC RESOLUTION"
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of variable lymphocyte receptor VLRA.R2.1 in complex with hen egg lysozyme"
    },
    {
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        ],
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        "temperature_c": 19.85
      },
      "construct": {
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      },
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        "url": "https://www.rcsb.org/structure/3M3U"
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Effect of temperature on tryptophan fluorescence in lysozyme crystals"
    },
    {
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        "environment": "in_vitro",
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          "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"
        ],
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        "ph": 6.5,
        "salt_mM": null,
        "temperature_c": -177.15
      },
      "construct": {
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        "labels": []
      },
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      "data_level": "processed",
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        "url": "https://www.rcsb.org/structure/3MBE"
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      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27)"
    },
    {
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        "environment": "in_vitro",
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        "ligands": [
          "CL"
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          "AU3",
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        "temperature_c": -149.95
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        "temperature_c": null
      },
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        "temperature_c": null
      },
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      },
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      },
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      "technique": "xray",
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
      "construct": {
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      "data_format": "mmCIF + structure factors",
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "ARG",
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          "NA"
        ],
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      "technique": "xray",
      "title": "Crystal structure of lysozyme in 40% ethanol"
    },
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          "EPE"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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        {
          "confidence": "medium",
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        }
      ],
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme in HEPES buffer at pH 7.5"
    },
    {
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          "NA",
          "branched: beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose"
        ],
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        "temperature_c": -173.15
      },
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      },
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        }
      ],
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    },
    {
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        ],
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        "salt_mM": null,
        "temperature_c": 21.85
      },
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      },
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      ],
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
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    },
    {
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          "CL",
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        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
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      },
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      "data_level": "processed",
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        {
          "confidence": "medium",
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        }
      ],
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        "url": "https://www.rcsb.org/structure/3TMV"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
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        }
      ],
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        "url": "https://www.rcsb.org/structure/3TMW"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Undosed)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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      },
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        "url": "https://www.rcsb.org/structure/3TMX"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Dose=1.9MGy)"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
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        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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          "confidence": "medium",
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        "url": "https://www.rcsb.org/structure/3TXB"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL co-crystallization with cisplatin in aqueous media with glycerol as the cryoprotectant"
    },
    {
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        "buffer": null,
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          "CL",
          "GOL",
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        ],
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        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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        {
          "confidence": "medium",
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      ],
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        "url": "https://www.rcsb.org/structure/3TXD"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
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          "CPT",
          "DMS",
          "GOL",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        }
      ],
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL co-crystallization with cisplatin in DMSO media with glycerol as the cryoprotectant"
    },
    {
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          "NA",
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        "ph": 4.7,
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "ph": 6.5,
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
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    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
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      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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      ],
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme contamination facilitates crystallization of a hetero-trimericCortactin:Arg:Lysozyme complex"
    },
    {
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          "CL",
          "NA",
          "RBN",
          "RU"
        ],
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        "ph": 4.5,
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
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      ],
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      },
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked wiht 5mM [Ru(benzene)Cl2]2"
    },
    {
      "conditions": {
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          "NA",
          "NO3"
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "LYSOZYME C (chains M)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4A8A",
      "evidence_id": "EV-PDB-4A8A-2",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
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        "unit": "Å",
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      },
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        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4A8A"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "cryoem",
      "title": "Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "LYSOZYME C (chains M,N,O,P,Q,R)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4A8B",
      "evidence_id": "EV-PDB-4A8B-2",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 13.0
      },
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        "doi": "10.1038/NSMB.2210",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4A8B"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "cryoem",
      "title": "Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes"
    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
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        "ligands": [
          "ACT",
          "CHT",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -210.15
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4AGA",
      "evidence_id": "EV-PDB-4AGA-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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        "unit": "Å",
        "value": 1.5
      },
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        "doi": "10.1039/C2CE25129A",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4AGA"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hofmeister effects of ionic liquids in protein crystallization: direct and water-mediated interactions"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4AXT",
      "evidence_id": "EV-PDB-4AXT-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.1
      },
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        "deposit_id": "4AXT",
        "doi": "10.1107/S0907444912031459",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4AXT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM AN AUTO HARVESTED CRYSTAL, Control Experiment"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "data_link": "https://www.rcsb.org/structure/4B0D",
      "evidence_id": "EV-PDB-4B0D-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 1.1
      },
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        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4B0D"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM AN AUTO HARVESTED CRYSTAL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "K3G",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -113.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4B1A",
      "evidence_id": "EV-PDB-4B1A-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "uncertainty": null,
        "unit": "Å",
        "value": 1.67
      },
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        "doi": "10.1039/C2DT32174B",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4B1A"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of lysozyme with Keggin molecule"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "MRD"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4B4E",
      "evidence_id": "EV-PDB-4B4E-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.0
      },
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        "doi": "10.1107/S1399004714025061",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4B4E"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "EU3",
          "HM6",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4BAD",
      "evidence_id": "EV-PDB-4BAD-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "unit": "Å",
        "value": 1.35
      },
      "provenance": {
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        "doi": "10.1039/C2CC36982F",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4BAD"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure in complex with the europium tris- hydroxymethyltriazoledipicolinate complex at 1.35 A resolution."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "EU3",
          "IKX",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4BAF",
      "evidence_id": "EV-PDB-4BAF-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "doi": "10.1039/C2CC36982F",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4BAF"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "DCJ",
          "EU3",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4BAP",
      "evidence_id": "EV-PDB-4BAP-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "doi": "10.1039/C2CC36982F",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4BAP"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethylcholinetriazoledipicolinate complex at 1.21 A resolution."
    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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          "YB"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4BS7",
      "evidence_id": "EV-PDB-4BS7-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "doi": "10.1021/CG301757G",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4BS7"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure determined at room temperature by in- situ diffraction and SAD phasing in ChipX"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "AIV",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4C3W",
      "evidence_id": "EV-PDB-4C3W-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "doi": "10.1002/EJIC.201402408",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4C3W"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Vanadium(IV)-Picolinate Complexed with Lysozyme"
    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4CJ2",
      "evidence_id": "EV-PDB-4CJ2-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.5
      },
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        "doi": "10.1371/JOURNAL.PONE.0097438",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4CJ2"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of HEWL in complex with affitin H4"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "GOL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,B,C)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4DC4",
      "evidence_id": "EV-PDB-4DC4-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
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    },
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        ],
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        "temperature_c": -173.15
      },
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      },
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        ],
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        ],
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        "temperature_c": -173.15
      },
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          "DMS"
        ],
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        "temperature_c": -173.15
      },
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        ],
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      },
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        "temperature_c": -173.15
      },
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      },
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      },
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      },
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      },
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4ET8",
      "evidence_id": "EV-PDB-4ET8-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4ET8"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme solved from 40 fs free-electron laser pulse data"
    },
    {
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        "environment": "in_vitro",
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          "EDO",
          "ZN"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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      "data_level": "processed",
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        {
          "confidence": "medium",
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        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of zinc-charged lysozyme"
    },
    {
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          "CPT",
          "DMS"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4DDC",
      "evidence_id": "EV-PDB-4DDC-1",
      "mappings": [
        {
          "confidence": "medium",
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        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4DDC"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "environment": "in_vitro",
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          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4DD0"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "GOL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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      "data_link": "https://www.rcsb.org/structure/4D9Z",
      "evidence_id": "EV-PDB-4D9Z-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4D9Z"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme at 318K"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
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          "CL",
          "MRD"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4B4J",
      "evidence_id": "EV-PDB-4B4J-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4B4J"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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          "CL",
          "MPD"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
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      "evidence_id": "EV-PDB-4B4I-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4B4I"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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          "CL",
          "TRS"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
        "labels": []
      },
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      "evidence_id": "EV-PDB-4B49-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4B49"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "LYSOZYME C (chains A)",
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      },
      "data_format": "mmCIF + structure factors",
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      "evidence_id": "EV-PDB-4A7D-1",
      "mappings": [
        {
          "confidence": "medium",
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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      "data_link": "https://www.rcsb.org/structure/4GN4",
      "evidence_id": "EV-PDB-4GN4-2",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "OBody AM2EP06 bound to hen egg-white lysozyme"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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          "EPE",
          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.4,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "data_link": "https://www.rcsb.org/structure/4GN5",
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        {
          "confidence": "medium",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "OBody AM3L15 bound to hen egg-white lysozyme"
    },
    {
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        "environment": "in_vitro",
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          "EU",
          "NA"
        ],
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        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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        {
          "confidence": "medium",
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Use of Europium for SAD Phasing at the Cu K alpha wavelength"
    },
    {
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        "applied_force_pn": null,
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        "environment": "in_vitro",
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          "CL",
          "EDO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.8,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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        {
          "confidence": "medium",
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Radiation damage study of lysozyme - 0.07 MGy"
    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "EDO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.8,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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          "confidence": "medium",
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          "state_id": "HEWL-native",
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        }
      ],
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      },
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LGK",
      "evidence_id": "EV-PDB-4LGK-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct between hen egg white lysozyme and Au2Phen, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers"
    },
    {
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          "MPD",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -163.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LT0"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL co-crystallized with Carboplatin in non-NaCl conditions: crystal 1 processed using the EVAL software package"
    },
    {
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          "DMS",
          "MPD",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -163.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LT1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LT1"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "environment": "in_vitro",
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          "DMS",
          "MPD",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -146.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LT2",
      "evidence_id": "EV-PDB-4LT2-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "type": "resolution",
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LT2"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CD"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LYB",
      "evidence_id": "EV-PDB-4LYB-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
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        "unit": "Å",
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      },
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        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LYB"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CdS within a lysoyzme single crystal"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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          "CD"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LYC",
      "evidence_id": "EV-PDB-4LYC-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.35
      },
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        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LYC"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Cd ions within a lysoyzme single crystal"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.3,
        "salt_mM": null,
        "temperature_c": 11.85
      },
      "construct": {
        "description": "LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LYO",
      "evidence_id": "EV-PDB-4LYO-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 2.05
      },
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        "doi": "10.1016/S0167-4838(98)00027-2",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LYO"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN NEAT ACETONITRILE, THEN BACK-SOAKED IN WATER"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
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        "ions": [],
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          "MG",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4M4O",
      "evidence_id": "EV-PDB-4M4O-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "url": "https://www.rcsb.org/structure/4M4O"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,C,E,G,I,K)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4M6D"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
        "description": "LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LZT",
      "evidence_id": "EV-PDB-4LZT-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
      "molecule_id": "P00698",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LZT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "ATOMIC RESOLUTION REFINEMENT OF TRICLINIC HEW LYSOZYME AT 295K"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LYZ",
      "evidence_id": "EV-PDB-4LYZ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Real-space refinement of the structure of hen egg-white lysozyme"
    },
    {
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        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LYT",
      "evidence_id": "EV-PDB-4LYT-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LYT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES"
    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LYM",
      "evidence_id": "EV-PDB-4LYM-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "deposit_id": "4LYM",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4LYM"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "CRYSTAL STRUCTURE OF LOW HUMIDITY TETRAGONAL LYSOZYME AT 2.1-ANGSTROMS RESOLUTION. VARIABILITY IN HYDRATION SHELL AND ITS STRUCTURAL CONSEQUENCES"
    },
    {
      "conditions": {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "DMS",
          "MPD",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -146.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4LT3",
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      "mappings": [
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          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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      ],
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      },
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        "doi": "10.1107/S2053230X14016161",
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        "source": "RCSB PDB",
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      "technique": "xray",
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    {
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
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        {
          "confidence": "medium",
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        }
      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "NA",
          "RU"
        ],
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        "temperature_c": null
      },
      "construct": {
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      },
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      ],
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "temperature_c": null
      },
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        }
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "CL",
          "EDO"
        ],
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        "temperature_c": -173.15
      },
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      },
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        }
      ],
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Radiation damage study of lysozyme - 0.98 MGy"
    },
    {
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          "BEN",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4N8Z"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "In situ lysozyme crystallized on a MiTeGen micromesh with benzamidine ligand"
    },
    {
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          "CL",
          "CS"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
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        }
      ],
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      },
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      },
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      "technique": "xray",
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    },
    {
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          "CL",
          "CS"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "applied_force_pn": null,
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        "environment": "in_vitro",
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          "RB"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      ],
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
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          "CO"
        ],
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        "temperature_c": 21.85
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 21.85
      },
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Previously de-ionized HEW lysozyme batch crystallized in 0.5 M YbCl3"
    },
    {
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        "applied_force_pn": null,
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        ],
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        "temperature_c": -173.15
      },
      "construct": {
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
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        "ph": 4.5,
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        "temperature_c": -173.15
      },
      "construct": {
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Dialyzed HEW lysozyme batch crystallized in 0.75 M YbCl3 and collected at 100 K"
    },
    {
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        "buffer": null,
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          "YB"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -148.15
      },
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        "url": "https://www.rcsb.org/structure/4NGZ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Previously de-ionized HEW lysozyme crystallized in 0.5 M YbCl3/30% (v/v) glycerol and collected at 125K"
    },
    {
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        "applied_force_pn": null,
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        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
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          "confidence": "medium",
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      },
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          "CL",
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      },
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        "temperature_c": -173.15
      },
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      },
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      },
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
      },
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      },
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        }
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    {
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        ],
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        "temperature_c": -173.15
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      },
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        "temperature_c": -173.15
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          "T3Y"
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        "temperature_c": -173.15
      },
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    {
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        "temperature_c": -173.15
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        "temperature_c": -173.15
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      },
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      },
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          "6BP",
          "ACT",
          "BR",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4OWH",
      "evidence_id": "EV-PDB-4OWH-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.484
      },
      "provenance": {
        "deposit_id": "4OWH",
        "doi": "10.1107/S2053230X14014009",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4OWH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "PtBr6 binding to HEWL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "NA",
          "PT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4OWE",
      "evidence_id": "EV-PDB-4OWE-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.41
      },
      "provenance": {
        "deposit_id": "4OWE",
        "doi": "10.1107/S2053230X14014009",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4OWE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "PtCl6 binding to HEWL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "IOD",
          "NA",
          "PT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4OWC",
      "evidence_id": "EV-PDB-4OWC-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.62
      },
      "provenance": {
        "deposit_id": "4OWC",
        "doi": "10.1107/S2053230X14014009",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4OWC"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "PtI6 binding to HEWL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "BR",
          "CL",
          "DMS",
          "MEB",
          "NA",
          "PT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4OWB",
      "evidence_id": "EV-PDB-4OWB-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.69
      },
      "provenance": {
        "deposit_id": "4OWB",
        "doi": "10.1107/S2053230X14013995",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4OWB"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Cisplatin binding to HEWL under sodium bromide crystallisation conditions"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "DMS",
          "IOD",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4OWA",
      "evidence_id": "EV-PDB-4OWA-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.796
      },
      "provenance": {
        "deposit_id": "4OWA",
        "doi": "10.1107/S2053230X14013995",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4OWA"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Carboplatin binding to HEWL under sodium iodide crystallisation conditions"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "RU0"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.2,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4OOO",
      "evidence_id": "EV-PDB-4OOO-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.15
      },
      "provenance": {
        "deposit_id": "4OOO",
        "doi": "10.1002/anie.201403337",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4OOO"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the lysozyme derivative of tetrakis(acetato)chlorido diruthenium(II,III) complex"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 22.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4O34",
      "evidence_id": "EV-PDB-4O34-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.09
      },
      "provenance": {
        "deposit_id": "4O34",
        "doi": "10.1107/S2052252514010070",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4O34"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Room temperature macromolecular serial crystallography using synchrotron radiation"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "RU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4NY5",
      "evidence_id": "EV-PDB-4NY5-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.85
      },
      "provenance": {
        "deposit_id": "4NY5",
        "doi": "10.1039/c3dt53582g",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4NY5"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed between hen egg white lysozyme and NAMI-A"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "XE"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4NWH",
      "evidence_id": "EV-PDB-4NWH-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.65
      },
      "provenance": {
        "deposit_id": "4NWH",
        "doi": "10.1097/ALN.0000000000000435",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4NWH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme UNDER 30 BAR PRESSURE OF XENON"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "N2O"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4NWE",
      "evidence_id": "EV-PDB-4NWE-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.58
      },
      "provenance": {
        "deposit_id": "4NWE",
        "doi": "10.1097/ALN.0000000000000435",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4NWE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme UNDER 30 BAR PRESSURE OF NITROUS OXIDE"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "DMS",
          "FMT",
          "NA",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4NSJ",
      "evidence_id": "EV-PDB-4NSJ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "4NSJ",
        "doi": "10.1107/S2053230X14016161",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4NSJ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Carboplatin binding to HEWL in 2M NH4formate, 0.1M HEPES at pH 7.5"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "DMS",
          "FLC",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 5.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4NSI",
      "evidence_id": "EV-PDB-4NSI-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.3
      },
      "provenance": {
        "deposit_id": "4NSI",
        "doi": "10.1107/S2053230X14016161",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4NSI"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Carboplatin binding to HEWL in 20% propanol, 20% PEG 4000 at pH5.6"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "DMS",
          "QPT",
          "SO4"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4NSH",
      "evidence_id": "EV-PDB-4NSH-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.1
      },
      "provenance": {
        "deposit_id": "4NSH",
        "doi": "10.1107/S2053230X14016161",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4NSH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Carboplatin binding to HEWL in 0.2M NH4SO4, 0.1M NaAc in 25% PEG 4000 at pH 4.6"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "BR",
          "DMS",
          "NA",
          "QPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4NSG",
      "evidence_id": "EV-PDB-4NSG-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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      },
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      ],
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    {
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      },
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    {
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      "source_kind": "deposit",
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    },
    {
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        ],
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        "temperature_c": -148.15
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      "construct": {
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      },
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    },
    {
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      },
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    },
    {
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        "temperature_c": 21.85
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        "temperature_c": 19.85
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
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        "temperature_c": -74.35
      },
      "construct": {
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    },
    {
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          "YPT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": null
      },
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
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    },
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      },
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
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      },
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        "temperature_c": -173.15
      },
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      },
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    },
    {
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        ],
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        "temperature_c": 19.85
      },
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      },
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        ],
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        "temperature_c": 19.85
      },
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      },
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    {
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        "temperature_c": 24.85
      },
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    {
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        ],
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        "temperature_c": 24.85
      },
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    {
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "NA"
        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": 24.85
      },
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      },
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      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "NA"
        ],
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        "temperature_c": 24.85
      },
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      },
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    {
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          "CL",
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        ],
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        "temperature_c": 24.85
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "CL",
          "NA"
        ],
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        "temperature_c": 24.85
      },
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        {
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      ],
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "Lysozyme C (chains A,B,C,D)",
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      },
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4WM6"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "High pressure protein crystallography of hen egg white lysozyme at 950 MPa"
    },
    {
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        "applied_force_pn": null,
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        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": 20.85
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "url": "https://www.rcsb.org/structure/4WMG"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "evidence_id": "EV-PDB-4WO6-1",
      "mappings": [
        {
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        "url": "https://www.rcsb.org/structure/4WO6"
      },
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    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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        {
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "url": "https://www.rcsb.org/structure/4WO9"
      },
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      },
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      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/4WOA",
      "evidence_id": "EV-PDB-4WOA-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/4WOA"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering"
    },
    {
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          "branched: beta-D-galactofuranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "data_link": "https://www.rcsb.org/structure/4XAD",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme in complex with Galf-GlcNAc"
    },
    {
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          "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
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      },
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      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa"
    },
    {
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          "CL",
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": 19.85
      },
      "construct": {
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      },
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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    },
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      },
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      },
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        "temperature_c": -173.15
      },
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      },
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        {
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        }
      ],
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      "source_kind": "deposit",
      "technique": "xray",
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    },
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          "CL",
          "NA"
        ],
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        "temperature_c": 19.85
      },
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      },
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        {
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        }
      ],
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "XFEL structure of hen egg-white lysozyme solved using a droplet injector at SACLA"
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    {
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        {
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        }
      ],
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      },
      "data_format": "mmCIF + structure factors",
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        {
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        }
      ],
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      },
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        "doi": "10.1021/acs.biomac.5b01743",
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        "url": "https://www.rcsb.org/structure/5F14"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Structure of native hen egg-white lysozyme"
    },
    {
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          "CPT",
          "GOL"
        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5F9X"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-RAY STRUCTURE OF THE ADDUCT BETWEEN HEN EGG WHITE LYSOZYME AND CISPLATIN UPON 24 HOURS OF INCUBATION AT 55 DEGREES"
    },
    {
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          "HFW",
          "K"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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      "evidence_id": "EV-PDB-5FHW-1",
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        {
          "confidence": "medium",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5FHW"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "buffer": null,
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          "KR",
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        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "GAI"
        ],
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        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      "technique": "xray",
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    },
    {
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          "DMS",
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
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    {
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        "temperature_c": -123.15
      },
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        "url": "https://www.rcsb.org/structure/5HMV"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Re refinement of 4mwk."
    },
    {
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          "NA",
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        "temperature_c": 26.85
      },
      "construct": {
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Re-refinement of 4g4a: room-temperature X-ray diffraction study of cisplatin and its binding to His15 of HEWL after 14 months chemical exposure in the presence of DMSO."
    },
    {
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        ],
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        "ph": 4.5,
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        "temperature_c": 19.85
      },
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      },
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        {
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        "doi": "10.1038/srep25558",
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        "url": "https://www.rcsb.org/structure/5FEL"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg lysozyme at room temperature solved from dataset acquired by oscillation method"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
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        "temperature_c": 19.85
      },
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      },
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      "mappings": [
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          "confidence": "medium",
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        "url": "https://www.rcsb.org/structure/5FEK"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "applied_force_pn": null,
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 24.85
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
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      ],
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      },
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "LYSOZYME (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LYM",
      "evidence_id": "EV-PDB-5LYM-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.8
      },
      "provenance": {
        "deposit_id": "5LYM",
        "doi": "10.1107/S0907444995009504",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LYM"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "STUDIES OF MONOCLINIC HEN EGG WHITE LYSOZYME. IV. X-RAY REFINEMENT AT 1.8 ANGSTROM RESOLUTION AND A COMPARISON OF THE VARIABLE REGIONS IN THE POLYMORPHIC FORMS"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LYT",
      "evidence_id": "EV-PDB-5LYT-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.9
      },
      "provenance": {
        "deposit_id": "5LYT",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LYT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5NJQ",
      "evidence_id": "EV-PDB-5NJQ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "5NJQ",
        "doi": "10.1107/S2052252517013124",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5NJQ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 1s time-delay, phased with 4ET8"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5O6Q",
      "evidence_id": "EV-PDB-5O6Q-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.45
      },
      "provenance": {
        "deposit_id": "5O6Q",
        "doi": "10.1107/S2059798317016357",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5O6Q"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "High pressure flash cooled hen egg white lysozyme"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "DO3",
          "GD",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5OER",
      "evidence_id": "EV-PDB-5OER-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.9
      },
      "provenance": {
        "deposit_id": "5OER",
        "doi": "10.1038/s41467-017-00754-7",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5OER"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme refined against 5000 9 keV diffraction patterns"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5OOV",
      "evidence_id": "EV-PDB-5OOV-2",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.365
      },
      "provenance": {
        "deposit_id": "5OOV",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5OOV"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Designed Ankyrin Repeat Protein (DARPin) ETVD-1 in complex with Lysozyme"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains B,F)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5OOY",
      "evidence_id": "EV-PDB-5OOY-2",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.72
      },
      "provenance": {
        "deposit_id": "5OOY",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5OOY"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Designed Ankyrin Repeat Protein (DARPin) VHAH-1 in complex with Lysozyme"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5TK0",
      "evidence_id": "EV-PDB-5TK0-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.795
      },
      "provenance": {
        "deposit_id": "5TK0",
        "doi": "10.1021/acs.analchem.7b00443",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5TK0"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme structure collected with 3D printed polymer mounts"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6ABN",
      "evidence_id": "EV-PDB-6ABN-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.17
      },
      "provenance": {
        "deposit_id": "6ABN",
        "doi": "10.1371/journal.pone.0232953",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6ABN"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal Structure of HEWL at pH 8.6"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "GAI",
          "GOL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6A4Q",
      "evidence_id": "EV-PDB-6A4Q-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.75
      },
      "provenance": {
        "deposit_id": "6A4Q",
        "doi": "10.1016/j.ijbiomac.2018.11.023",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6A4Q"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL crystals soaked in 2.5M GuHCl for 110 minutes"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "GAI",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6A4P",
      "evidence_id": "EV-PDB-6A4P-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.76
      },
      "provenance": {
        "deposit_id": "6A4P",
        "doi": "10.1016/j.ijbiomac.2018.11.023",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6A4P"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL crystals soaked in 2.5M GuHCl for 40 minutes"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "GAI",
          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6A4O",
      "evidence_id": "EV-PDB-6A4O-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.75
      },
      "provenance": {
        "deposit_id": "6A4O",
        "doi": "10.1016/j.ijbiomac.2018.11.023",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6A4O"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL crystals soaked in 2.5M GuHCl for 20 minutes"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "GAI",
          "GOL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6A4N",
      "evidence_id": "EV-PDB-6A4N-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.75
      },
      "provenance": {
        "deposit_id": "6A4N",
        "doi": "10.1016/j.ijbiomac.2018.11.023",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6A4N"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL crystals soaked in 2.5M GuHCl for 8 minutes"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "SO4"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 6.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,B,C)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6A10",
      "evidence_id": "EV-PDB-6A10-1",
      "mappings": [
        {
          "confidence": "medium",
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      },
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    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      },
      "data_format": "mmCIF + structure factors",
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        {
          "confidence": "medium",
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        }
      ],
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      },
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    },
    {
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          "ACT",
          "CL",
          "NA",
          "RU2"
        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      ],
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      },
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    },
    {
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          "9QB",
          "CL",
          "GOL",
          "NA",
          "RU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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    },
    {
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          "CL",
          "GOL",
          "NA",
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        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "technique": "xray",
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    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
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      ],
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    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
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      ],
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "microed",
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    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.5,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
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      },
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      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5NJS"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.5,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "temperature_c": 21.85
      },
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      },
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    {
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        "temperature_c": 19.85
      },
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        "temperature_c": -173.15
      },
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      },
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      },
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        "temperature_c": -173.15
      },
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      },
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    },
    {
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          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -193.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5MYY",
      "evidence_id": "EV-PDB-5MYY-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.1
      },
      "provenance": {
        "deposit_id": "5MYY",
        "doi": "10.1107/S2059798317006970",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5MYY"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg-White Lysozyme (HEWL) cocrystallized in the presence of Cadmium sulphate"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5MJJ",
      "evidence_id": "EV-PDB-5MJJ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.75009201311
      },
      "provenance": {
        "deposit_id": "5MJJ",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5MJJ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Single-shot pink beam serial crystallography: Lysozyme"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "DMS",
          "IOD",
          "NA",
          "PT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5M1Y",
      "evidence_id": "EV-PDB-5M1Y-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.904
      },
      "provenance": {
        "deposit_id": "5M1Y",
        "doi": "10.5281/zenodo.160328",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5M1Y"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "The case of 1lkr held at the PDB and its variable amino acid occupancies; re refinement of 4ow9 to correct this"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LYZ",
      "evidence_id": "EV-PDB-5LYZ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.0
      },
      "provenance": {
        "deposit_id": "5LYZ",
        "doi": "10.1016/0022-2836(74)90598-1",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LYZ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Real-space refinement of the structure of hen egg-white lysozyme"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "GOL",
          "NA",
          "RU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -153.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LVJ",
      "evidence_id": "EV-PDB-5LVJ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.6
      },
      "provenance": {
        "deposit_id": "5LVJ",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LVJ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme co-crystallized with [H2Ind][trans-RuCl4(DMSO)(HInd)]"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "NA",
          "RU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -153.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LVI",
      "evidence_id": "EV-PDB-5LVI-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "5LVI",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LVI"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme co-crystallized with [HIsq][trans-RuCl4(DMSO)(Isq)]"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "GOL",
          "NA",
          "RU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -153.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LVH",
      "evidence_id": "EV-PDB-5LVH-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.55
      },
      "provenance": {
        "deposit_id": "5LVH",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LVH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme co-crystallized with trans-Ru(DMSO)4Cl2"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "NA",
          "RU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -153.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LVG",
      "evidence_id": "EV-PDB-5LVG-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.0
      },
      "provenance": {
        "deposit_id": "5LVG",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LVG"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme co-crystallized with cis-Ru(DMSO)4Cl2"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/5LIO",
      "evidence_id": "EV-PDB-5LIO-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.496
      },
      "provenance": {
        "deposit_id": "5LIO",
        "doi": "10.1107/S2059798316012304",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/5LIO"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme, collected at rotation 360 degree per second"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "9U3",
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6AD5",
      "evidence_id": "EV-PDB-6AD5-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.",
          "rule": "hewl-fibril-structures",
          "state_id": "HEWL-fibril",
          "who": "rule:hewl-fibril-structures"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.75
      },
      "provenance": {
        "deposit_id": "6AD5",
        "doi": "10.1371/journal.pone.0232953",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6AD5"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal Structure of HEWL in complex with TEMED (in the aroma form) after 24 hours under fibrillation conditions"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "9U3",
          "ACT",
          "CL",
          "NA",
          "PGO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6ADF",
      "evidence_id": "EV-PDB-6ADF-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.08
      },
      "provenance": {
        "deposit_id": "6ADF",
        "doi": "10.1371/journal.pone.0232953",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6ADF"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Structure of HEWL co-crystallised with TEMED"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "9U3",
          "CL",
          "NA",
          "PGO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6AEA",
      "evidence_id": "EV-PDB-6AEA-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.",
          "rule": "hewl-fibril-structures",
          "state_id": "HEWL-fibril",
          "who": "rule:hewl-fibril-structures"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.4
      },
      "provenance": {
        "deposit_id": "6AEA",
        "doi": "10.1371/journal.pone.0232953",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6AEA"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal Structure of HEWL in complex with TEMED (in the aroma form) after 5 hours under fibrillation conditions"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "EDO",
          "NA",
          "PEL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6AGR",
      "evidence_id": "EV-PDB-6AGR-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.22
      },
      "provenance": {
        "deposit_id": "6AGR",
        "doi": "10.1016/j.ijbiomac.2019.12.204",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6AGR"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Structure of HEWL co-crystallised with phenylethyl alcohol"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "PEL",
          "PGO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6AHH",
      "evidence_id": "EV-PDB-6AHH-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.",
          "rule": "hewl-fibril-structures",
          "state_id": "HEWL-fibril",
          "who": "rule:hewl-fibril-structures"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.1
      },
      "provenance": {
        "deposit_id": "6AHH",
        "doi": "10.1038/s41598-019-55082-1",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6AHH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal Structure of HEWL in complex with Phenylethyl alcohol (in the aroma form) after 5 hours under fibrillation conditions"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CIN",
          "CL",
          "NA",
          "PGO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6AHL",
      "evidence_id": "EV-PDB-6AHL-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.",
          "rule": "hewl-fibril-structures",
          "state_id": "HEWL-fibril",
          "who": "rule:hewl-fibril-structures"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.8
      },
      "provenance": {
        "deposit_id": "6AHL",
        "doi": "10.1038/s41598-019-55082-1",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6AHL"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal Structure of HEWL in complex with Cinnamaldehyde (in the aroma form) after 5 hours under fibrillation conditions"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "GOL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6B7U",
      "evidence_id": "EV-PDB-6B7U-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.581
      },
      "provenance": {
        "deposit_id": "6B7U",
        "doi": "10.1016/j.ifset.2018.02.008",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6B7U"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Structure of hen egg-white lysozyme without high-pressure pre-treatment"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "GOL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6B7V",
      "evidence_id": "EV-PDB-6B7V-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.482
      },
      "provenance": {
        "deposit_id": "6B7V",
        "doi": "10.1016/j.ifset.2018.02.008",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6B7V"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Structure of hen egg-white lysozyme pre-treated with high-pressure homogenization at 120 MPa"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "E3D",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6BO1",
      "evidence_id": "EV-PDB-6BO1-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.24
      },
      "provenance": {
        "deposit_id": "6BO1",
        "doi": "10.1039/c8cc02433b",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6BO1"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Mono-adduct formed after 3 days in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "E3D",
          "NA",
          "RU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.7,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6BO2",
      "evidence_id": "EV-PDB-6BO2-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.48
      },
      "provenance": {
        "deposit_id": "6BO2",
        "doi": "10.1039/c8cc02433b",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6BO2"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Adducts formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CD",
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6BRE",
      "evidence_id": "EV-PDB-6BRE-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.86
      },
      "provenance": {
        "deposit_id": "6BRE",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6BRE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg-White Lysozyme cocrystallized with Cadmium sulphate using CuKalpha source."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "F44"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6CIW",
      "evidence_id": "EV-PDB-6CIW-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.42
      },
      "provenance": {
        "deposit_id": "6CIW",
        "doi": "10.1039/C8PY00545A",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6CIW"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme Cocrystallized with 1,3-Di(2-pyridyl)propane"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6D6E",
      "evidence_id": "EV-PDB-6D6E-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.0
      },
      "provenance": {
        "deposit_id": "6D6E",
        "doi": "10.1107/S2059798318008793",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6D6E"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Triclinic lysozyme (295 K) in the presence of 47% xylose"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NO3",
          "XYS"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6D6F",
      "evidence_id": "EV-PDB-6D6F-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.0
      },
      "provenance": {
        "deposit_id": "6D6F",
        "doi": "10.1107/S2059798318008793",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6D6F"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Triclinic lysozyme cryocooled to 100 K with 47% xylose as cryoprotectant"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6D6G",
      "evidence_id": "EV-PDB-6D6G-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.0
      },
      "provenance": {
        "deposit_id": "6D6G",
        "doi": "10.1107/S2059798318008793",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6D6G"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Triclinic lysozyme (295 K) in the presence of 47% MPD"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "MRD",
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6D6H",
      "evidence_id": "EV-PDB-6D6H-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.00006383515
      },
      "provenance": {
        "deposit_id": "6D6H",
        "doi": "10.1107/S2059798318008793",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6D6H"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Triclinic lysozyme cryocooled to 100 K with 47% MPD as cryoprotectant"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6F1M",
      "evidence_id": "EV-PDB-6F1M-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.48
      },
      "provenance": {
        "deposit_id": "6F1M",
        "doi": "10.1107/S205979831800517X",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6F1M"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme crystallized in presence of 100 mM sodium phosphate at pH 4.5: low-humidity form"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "PO4"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6F1O",
      "evidence_id": "EV-PDB-6F1O-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 0.96
      },
      "provenance": {
        "deposit_id": "6F1O",
        "doi": "10.1107/S205979831800517X",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6F1O"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Orthorhombic Lysozyme crystallized at 298 K and pH 4.5"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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          "ACT",
          "CL",
          "GOL",
          "NA"
        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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      },
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        "url": "https://www.rcsb.org/structure/6B7W"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 24.85
      },
      "construct": {
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      },
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        {
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        }
      ],
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        "unit": "Å",
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      },
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      },
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      "technique": "xray",
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    },
    {
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          "9Y6",
          "CL",
          "EDO",
          "NA"
        ],
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        "temperature_c": -173.15
      },
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      },
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        {
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        }
      ],
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      "technique": "xray",
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    },
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          "CL",
          "NA",
          "PGO"
        ],
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
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        }
      ],
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        "url": "https://www.rcsb.org/structure/6AC2"
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      "technique": "xray",
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    },
    {
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          "NA",
          "PGO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        {
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        }
      ],
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6HT2",
      "evidence_id": "EV-PDB-6HT2-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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      },
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        "doi": "10.1107/S2052252518017657",
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        "url": "https://www.rcsb.org/structure/6HT2"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "STRUCTURE OF HEWL BY ELECTRON DIFFRACTION AND MICROFOCUS DIFFRACTION"
    },
    {
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          "CL",
          "CWO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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          "confidence": "medium",
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        }
      ],
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "applied_force_pn": null,
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          "CL",
          "GXZ"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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        {
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        }
      ],
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "K",
          "ZRW"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "NA"
        ],
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        "ph": null,
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        "temperature_c": 22.85
      },
      "construct": {
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      },
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      "source_kind": "deposit",
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    {
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          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "NA",
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of nanobody D3-L11 in complex with hen egg-white lysozyme"
    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": 25.0
      },
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      },
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": 25.0
      },
      "construct": {
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      },
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          "confidence": "medium",
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      },
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        "temperature_c": null
      },
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      },
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      },
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
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        "unit": "Å",
        "value": 1.05
      },
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        "doi": "10.1073/pnas.2005102117",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6P4D"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg lysozyme (HEL) containing three point mutations (HEL3x): R21Q, R73E, and D101R"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
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        "ions": [],
        "ligands": [
          "NA",
          "ORS",
          "R1N"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6PL9",
      "evidence_id": "EV-PDB-6PL9-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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        }
      ],
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        "unit": "Å",
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      },
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        "doi": "10.1002/anie.202106906",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6PL9"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Adduct formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidaz ol-2-ylidene)(eta5-pentamethylcyclopentadienyl)rhodium(III) with HEWL"
    },
    {
      "conditions": {
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          "NA",
          "O1N",
          "OS"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6PLA"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Adducts formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)osmium(II) with HEWL"
    },
    {
      "conditions": {
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        "ligands": [
          "NA",
          "OT1"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme (chains A)",
        "labels": []
      },
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          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6PLB"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Adducts formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimida zol-2-ylidene)(eta5-pentamethylcyclopentadienyl)iridium(III) with HEWL"
    },
    {
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        "buffer": null,
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          "CL",
          "PEG"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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        "url": "https://www.rcsb.org/structure/6Q88"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "environment": "in_vitro",
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          "ACT",
          "AR",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.8,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      },
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 1.7
      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6Q8R"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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          "CL",
          "PEG"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6Q8T"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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    },
    {
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          "ACT",
          "CL",
          "NA"
        ],
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        "ph": 4.8,
        "salt_mM": null,
        "temperature_c": 20.85
      },
      "construct": {
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        "labels": []
      },
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      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6QQ3"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.8,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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        {
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          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
      "molecule_id": "P00698",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6QQC"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.8,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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        {
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      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6QQD"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Cryogenic temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 10 MGy"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 19.85
      },
      "construct": {
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        {
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          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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        "url": "https://www.rcsb.org/structure/6QQF"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
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          "CU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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      "data_link": "https://www.rcsb.org/structure/6QWW",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
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      ],
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6QWW"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL lysozyme, crystallized from CuCl2 solution"
    },
    {
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        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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          "NI"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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        {
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          "who": "rule:hewl-structures-native"
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      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6QWX"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL lysozyme, crystallized from NiCl2 solution"
    },
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          "CL",
          "NA"
        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
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      "source_kind": "deposit",
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        "url": "https://www.rcsb.org/structure/6QWZ"
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      "source_kind": "deposit",
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      "source_kind": "deposit",
      "technique": "xray",
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          "J9H",
          "NO3"
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        "temperature_c": -173.15
      },
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      },
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        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/6QEA"
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands"
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          "I3C"
        ],
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        "temperature_c": -173.15
      },
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "evidence_id": "EV-PDB-6PBB-1",
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        {
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        "url": "https://www.rcsb.org/structure/6PBB"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/6P4B",
      "evidence_id": "EV-PDB-6P4B-3",
      "mappings": [
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          "confidence": "medium",
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        }
      ],
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        "url": "https://www.rcsb.org/structure/6P4B"
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      "technique": "xray",
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        ],
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        "temperature_c": 24.85
      },
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      },
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      "technique": "xray",
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        "temperature_c": -173.15
      },
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    {
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        ],
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        "temperature_c": 19.85
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      "technique": "xray",
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    {
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        "temperature_c": -173.15
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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      },
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        "temperature_c": -173.15
      },
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    },
    {
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        "environment": "in_vitro",
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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        "url": "https://www.rcsb.org/structure/6HU5"
      },
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      "technique": "microed",
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    },
    {
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        "temperature_c": 19.85
      },
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    {
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        "applied_force_pn": null,
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          "SO4"
        ],
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        "temperature_c": -173.15
      },
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      },
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      ],
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        ],
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        "temperature_c": -173.15
      },
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      ],
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        "temperature_c": -173.15
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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          "CL",
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        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
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      ],
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        "url": "https://www.rcsb.org/structure/6SIK"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "SAD structure of Hen Egg White Lysozyme recovered by continuous rotation data collection and univariate analysis"
    },
    {
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        "temperature_c": 19.85
      },
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      "technique": "xray",
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    },
    {
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        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "temperature_c": 19.85
      },
      "construct": {
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      "source_kind": "deposit",
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    {
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        "ph": 6.5,
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
      "construct": {
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        "temperature_c": 19.85
      },
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    {
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
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        ],
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
      },
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        "temperature_c": 19.85
      },
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        "temperature_c": 19.85
      },
      "construct": {
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      },
      "construct": {
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      },
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      },
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      },
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      "technique": "xray",
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": null
      },
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      },
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      },
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        "temperature_c": 19.85
      },
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      },
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      "technique": "xray",
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
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        "temperature_c": 24.85
      },
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      },
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        "temperature_c": 24.85
      },
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      },
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        "temperature_c": -173.15
      },
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    {
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        "temperature_c": -173.15
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "ACY",
          "AE3",
          "BR",
          "NA"
        ],
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        "temperature_c": -173.15
      },
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      },
      "data_format": "mmCIF + structure factors",
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      ],
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        "url": "https://www.rcsb.org/structure/6YOE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Structure of Lysozyme from SiN IMISX setup collected by still serial crystallography on crystals prelocated by 2D X-ray phase-contrast imaging"
    },
    {
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        ],
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        "temperature_c": -173.15
      },
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      },
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        }
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      "technique": "xray",
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          "EDO",
          "NA",
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        ],
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        "temperature_c": -173.15
      },
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      },
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        "url": "https://www.rcsb.org/structure/7A70"
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        ],
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        "temperature_c": -173.15
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "ACT",
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        "url": "https://www.rcsb.org/structure/7AVE"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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          "CL",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
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    {
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        "ph": 4.5,
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        "temperature_c": -173.15
      },
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      },
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    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -173.15
      },
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      },
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      "source_kind": "deposit",
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        "temperature_c": -173.15
      },
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      },
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          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
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        "value": 1.4
      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BE1"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of Hen Egg White Lysozyme with dirhodium tetraacetate (3)"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
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          "ACT",
          "GOL",
          "NA",
          "RH"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/7BE2",
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        {
          "confidence": "medium",
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        }
      ],
      "molecule_id": "P00698",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BE2"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
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          "EDO",
          "NA",
          "NO3",
          "RH"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
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          "who": "rule:hewl-structures-native"
        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BEB"
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "buffer": null,
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          "ACT",
          "EDO",
          "NA",
          "NO3",
          "RH"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
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        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BEC"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 34.85
      },
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        "labels": []
      },
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        {
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          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BHK"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme using drop-on-drop SFX method."
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 34.85
      },
      "construct": {
        "description": "Lysozyme (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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        {
          "confidence": "medium",
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        }
      ],
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BHL"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme using drop-on-drop SFX method - 0.2 s mixing with N-acetyl-D-glucosamine."
    },
    {
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        "applied_force_pn": null,
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          "CL",
          "NA",
          "NDG"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 34.85
      },
      "construct": {
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      },
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      "evidence_id": "EV-PDB-7BHM-1",
      "mappings": [
        {
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        }
      ],
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      },
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme using drop-on-drop SFX method - 0.7 s mixing with N-acetyl-D-glucosamine."
    },
    {
      "conditions": {
        "applied_force_pn": null,
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          "CL",
          "NA",
          "NDG"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 34.85
      },
      "construct": {
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      ],
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme using drop-on-drop SFX method - 2 s mixing with N-acetyl-D-glucosamine."
    },
    {
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          "EDO",
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Hen egg white lysozyme (chains A)",
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      },
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        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BMO"
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "applied_force_pn": null,
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          "CS",
          "EDO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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      ],
      "molecule_id": "P00698",
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        "url": "https://www.rcsb.org/structure/7BMP"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL in cesium chloride (0.25 M CsCl in protein buffer and cryo protectant)."
    },
    {
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        "ions": [],
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          "CL",
          "CS",
          "EDO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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          "who": "rule:hewl-structures-native"
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CS",
          "EDO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
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        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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        {
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      ],
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        "url": "https://www.rcsb.org/structure/7BMS"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL in cesium chloride (1.5 M CsCl in crystallization condition and cryo protectant)"
    },
    {
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        "applied_force_pn": null,
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        "environment": "in_vitro",
        "ions": [],
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          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
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        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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      "data_level": "processed",
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      "evidence_id": "EV-PDB-7BMT-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
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      ],
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      },
      "provenance": {
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        "doi": "10.1038/s41598-021-95186-1",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/7BMT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL in sodium chloride"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
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      "data_link": "https://www.rcsb.org/structure/7BR5",
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        {
          "confidence": "medium",
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      ],
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      },
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      "technique": "xray",
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        "temperature_c": -173.15
      },
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      },
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        "temperature_c": -173.15
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        "temperature_c": -173.15
      },
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      },
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      },
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      "source_kind": "deposit",
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      },
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      },
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      },
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      },
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        "temperature_c": -173.15
      },
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        "temperature_c": -173.15
      },
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        ],
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      },
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      },
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        "temperature_c": -173.15
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      },
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        }
      ],
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        "type": "resolution",
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of lysozyme obtained upon reaction with [VIVO(malt)2] (Structure B)"
    },
    {
      "conditions": {
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        "buffer": null,
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          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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        {
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        }
      ],
      "molecule_id": "P00698",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8B3U"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme 6s in situ crystallization"
    },
    {
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        "environment": "in_vitro",
        "ions": [],
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          "NO3",
          "PT",
          "R0I"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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        }
      ],
      "molecule_id": "P00698",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BOY"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of the five-coordinate Pt(II) complex, 1-Me,Me, with HEWL at pH 4.0"
    },
    {
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          "R3D",
          "SIN"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8BPH",
      "evidence_id": "EV-PDB-8BPH-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 1.07
      },
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        "doi": "10.1021/acs.inorgchem.2c04103",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BPH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(D-p-FPhF)(O2CCH3)3] (Structure 3)"
    },
    {
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        "applied_force_pn": null,
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          "NA",
          "NO3",
          "TZ6"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8BPJ",
      "evidence_id": "EV-PDB-8BPJ-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BPJ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(D-p-FPhF)(O2CCH3)3] (Structure 1)"
    },
    {
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          "ACT",
          "CL",
          "NA",
          "R2U"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
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      "evidence_id": "EV-PDB-8BQM-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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        }
      ],
      "molecule_id": "P00698",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BQM"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "ACT",
          "CL",
          "U7U"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8BQP",
      "evidence_id": "EV-PDB-8BQP-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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      },
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        "doi": "10.1039/d2fd00161f",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BQP"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg-White Lysozyme (HEWL) complexed with methyl-functionalised Anderson-Evans polyoxometalate"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
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          "CL",
          "RJU"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8BQQ",
      "evidence_id": "EV-PDB-8BQQ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "uncertainty": null,
        "unit": "Å",
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      },
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        "doi": "10.1039/d2fd00161f",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BQQ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg-White Lysozyme (HEWL) complexed with amine-functionalised Anderson-Evans polyoxometalate"
    },
    {
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        "buffer": null,
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        "ions": [],
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          "CA",
          "R9H"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8BQR",
      "evidence_id": "EV-PDB-8BQR-1",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
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      },
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        "doi": "10.1039/d2fd00161f",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BQR"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg-White Lysozyme (HEWL) complexed with biotin-functionalised Anderson-Evans polyoxometalate"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
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          "CL",
          "U7U"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "data_link": "https://www.rcsb.org/structure/8BQT",
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
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      ],
      "molecule_id": "P00698",
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      },
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        "doi": "10.1039/d2fd00161f",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8BQT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg-White Lysozyme (HEWL) complexed with two methyl-functionalised Anderson-Evans polyoxometalates"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
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        "ions": [],
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          "1PE",
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 21.85
      },
      "construct": {
        "description": "LYSOZYME, Chain A (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8CL6",
      "evidence_id": "EV-PDB-8CL6-1",
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        "source": "RCSB PDB",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme in matrix of hydroxyethylcellulose (HEC)"
    },
    {
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        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
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        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      },
      "data_format": "mmCIF",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8CPC",
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          "confidence": "medium",
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "microed",
      "title": "3D electron diffraction structure of Hen Egg-White Lysozyme from nano-crystals obtained by high pressure freezing and cryo-sectioning"
    },
    {
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          "CL",
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        ],
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        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 17.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8CVU",
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        {
          "confidence": "medium",
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        "source": "RCSB PDB",
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "20ns Temperature-Jump (Light) XFEL structure of Lysozyme"
    },
    {
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          "NA"
        ],
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        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 17.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "data_link": "https://www.rcsb.org/structure/8CVV",
      "evidence_id": "EV-PDB-8CVV-1",
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        {
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      ],
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          "NA"
        ],
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      },
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      },
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      },
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      },
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      "source_kind": "deposit",
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    },
    {
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        "salt_mM": null,
        "temperature_c": -148.15
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
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        "temperature_c": -148.15
      },
      "construct": {
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -148.15
      },
      "construct": {
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      ],
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme at 125 Kelvin (Triplicate)"
    },
    {
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        "applied_force_pn": null,
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -123.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "temperature_c": -123.15
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "temperature_c": -123.15
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "temperature_c": -98.15
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme at 175 Kelvin"
    },
    {
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        "temperature_c": 17.85
      },
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      },
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    },
    {
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        "temperature_c": 17.85
      },
      "construct": {
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        "url": "https://www.rcsb.org/structure/8CW5"
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "EDO",
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        "temperature_c": 21.85
      },
      "construct": {
        "description": "LYSOZYME, Chain A (chains A)",
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      },
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      "data_level": "processed",
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      "evidence_id": "EV-PDB-8CL5-1",
      "mappings": [
        {
          "confidence": "medium",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme in matrix of lipidic cubic phase of monoolein (LCP)"
    },
    {
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          "NA",
          "NO3",
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        ],
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        "temperature_c": -173.15
      },
      "construct": {
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        "labels": []
      },
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      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8C39",
      "evidence_id": "EV-PDB-8C39-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
      ],
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      },
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        "source": "RCSB PDB",
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      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of HEWL upon reaction with a Ruthenium(II)-arene Complexed with Glycosylated Carbene Ligands (5)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
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          "NA",
          "R2I",
          "R2U"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
      "data_format": "mmCIF + structure factors",
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        {
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          "state_id": "HEWL-native",
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        }
      ],
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        "url": "https://www.rcsb.org/structure/8BPU"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(D-p-FPhF)(O2CCH3)3] (Structure 2)"
    },
    {
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          "DMS",
          "EPE",
          "R0I"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        }
      ],
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        "url": "https://www.rcsb.org/structure/8BOV"
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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          "CL",
          "EDO",
          "NA"
        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        "labels": []
      },
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      "data_level": "processed",
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        {
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        }
      ],
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8B3V"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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      },
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        {
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        }
      ],
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        "url": "https://www.rcsb.org/structure/8B3T"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "EDO",
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        ],
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        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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      },
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      "evidence_id": "EV-PDB-8B3L-1",
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        {
          "confidence": "medium",
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        }
      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
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        "buffer": null,
        "environment": "in_vitro",
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          "GOL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": -98.15
      },
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      },
      "data_format": "mmCIF + structure factors",
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        "url": "https://www.rcsb.org/structure/8D6B"
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "applied_force_pn": null,
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          "GOL",
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        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -98.15
      },
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      },
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      ],
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        "url": "https://www.rcsb.org/structure/8D6I"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme at 175 Kelvin (Triplicate)"
    },
    {
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          "NA"
        ],
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        "temperature_c": -73.15
      },
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "temperature_c": -73.15
      },
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      "technique": "xray",
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        "temperature_c": -73.15
      },
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      "source_kind": "deposit",
      "technique": "xray",
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        "url": "https://www.rcsb.org/structure/8D7B"
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      "source_kind": "deposit",
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    },
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        "ph": 4.6,
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        "temperature_c": -48.15
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of hen egg white lysozyme at 225 Kelvin (Duplicate)"
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        "temperature_c": -48.15
      },
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      },
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        "temperature_c": null
      },
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      },
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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        "temperature_c": -173.15
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      },
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    },
    {
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        "ligands": [
          "EPE",
          "ZJK"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PH5",
      "evidence_id": "EV-PDB-8PH5-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.29
      },
      "provenance": {
        "deposit_id": "8PH5",
        "doi": "10.1016/j.ijbiomac.2023.126666",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PH5"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DPhF)2(O2CCH3)2] in condition B"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "EPE",
          "YWV",
          "ZWL",
          "ZWO",
          "ZXE"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PH6",
      "evidence_id": "EV-PDB-8PH6-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.07
      },
      "provenance": {
        "deposit_id": "8PH6",
        "doi": "10.1016/j.ijbiomac.2023.126666",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PH6"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(DPhF)(CO3)3] in condition B"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "TB",
          "ZHT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PIW",
      "evidence_id": "EV-PDB-8PIW-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.72
      },
      "provenance": {
        "deposit_id": "8PIW",
        "doi": "10.1002/chem.202400900",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PIW"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of Hen Egg White Lysozyme co-crystallized with 10 mM TbXo4-NMet2"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "TB",
          "ZW0"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8POB",
      "evidence_id": "EV-PDB-8POB-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.74
      },
      "provenance": {
        "deposit_id": "8POB",
        "doi": "10.1002/chem.202400900",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8POB"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of Hen Egg White Lysozyme co-crystallized with 10 mM TbXo4-SO3"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "BR",
          "CL",
          "IMD",
          "NA",
          "RE",
          "REI",
          "VHL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8QCU",
      "evidence_id": "EV-PDB-8QCU-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.15
      },
      "provenance": {
        "deposit_id": "8QCU",
        "doi": "10.1107/S2052252524002598",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8QCU"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme covalently bound to fac-[Re(CO)3-imidazole] complex, incubated for 38 weeks."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains A,C,E,G,I)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8QV8",
      "evidence_id": "EV-PDB-8QV8-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.",
          "rule": "hewl-fibril-structures",
          "state_id": "HEWL-fibril",
          "who": "rule:hewl-fibril-structures"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 3.26
      },
      "provenance": {
        "deposit_id": "8QV8",
        "doi": "10.1038/s41467-024-52681-z",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8QV8"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "cryoem",
      "title": "Cryo-EM structure of the heat-irreversible amyloid fibrils of hen egg-white lysozyme"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "H1W",
          "JQJ",
          "NA",
          "NO3"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PTE",
      "evidence_id": "EV-PDB-8PTE-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.797
      },
      "provenance": {
        "deposit_id": "8PTE",
        "doi": "10.1002/anie.202310655",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PTE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Polyoxidovanadate interaction with proteins: crystal structure of lysozyme bound to octadecavanadate ion (structure B)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NA",
          "SIN",
          "ZJO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PH8",
      "evidence_id": "EV-PDB-8PH8-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.29
      },
      "provenance": {
        "deposit_id": "8PH8",
        "doi": "10.1016/j.ijbiomac.2023.126666",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PH8"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DPhF)2(O2CCH3)2] in condition A"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "NA",
          "SIN",
          "ZQ2",
          "ZWH"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PH7",
      "evidence_id": "EV-PDB-8PH7-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.406
      },
      "provenance": {
        "deposit_id": "8PH7",
        "doi": "10.1016/j.ijbiomac.2023.126666",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PH7"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DPhF)(O2CCH3)3] in condition A"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "NO3",
          "YWR"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PFW",
      "evidence_id": "EV-PDB-8PFW-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.12
      },
      "provenance": {
        "deposit_id": "8PFW",
        "doi": "10.1039/D3QI01192E",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PFW"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(DAniF)(CO3)3] in condition A"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "NO3",
          "YMQ"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PFV",
      "evidence_id": "EV-PDB-8PFV-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.46
      },
      "provenance": {
        "deposit_id": "8PFV",
        "doi": "10.1039/D3QI01192E",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PFV"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DAniF)(O2CCH3)3] in condition A"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CO3",
          "NA",
          "NO3",
          "YJT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PFU",
      "evidence_id": "EV-PDB-8PFU-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.18
      },
      "provenance": {
        "deposit_id": "8PFU",
        "doi": "10.1039/D3QI01192E",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PFU"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with K3[Ru2(CO3)4] in condition A"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "NO3",
          "YJT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/8PFT",
      "evidence_id": "EV-PDB-8PFT-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.304
      },
      "provenance": {
        "deposit_id": "8PFT",
        "doi": "10.1039/D3QI01192E",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/8PFT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(D-p-FPhF)(CO3)3] in condition A"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "EDO"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
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      ],
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      },
      "reader": null,
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    },
    {
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      ],
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    },
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        ],
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        "temperature_c": 20.0
      },
      "construct": {
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      },
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          "NA",
          "NO3",
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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          "EPE",
          "VVB",
          "VVO"
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      },
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      },
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          "NA",
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        "temperature_c": 24.85
      },
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      },
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      ],
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    {
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        ],
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        "temperature_c": 19.85
      },
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      },
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        "temperature_c": 21.85
      },
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        "temperature_c": 21.85
      },
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        ],
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        "temperature_c": 21.85
      },
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        "temperature_c": 24.85
      },
      "construct": {
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      },
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        {
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    },
    {
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        "temperature_c": 24.85
      },
      "construct": {
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      },
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        "temperature_c": 24.85
      },
      "construct": {
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      "source_kind": "deposit",
      "technique": "xray",
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    {
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        "temperature_c": 24.85
      },
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      },
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      },
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      },
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      },
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      },
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      },
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        "temperature_c": -173.15
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      },
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      },
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        "temperature_c": -173.15
      },
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      },
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      },
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      ],
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        "temperature_c": 24.85
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      },
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    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains D,F)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9FGX",
      "evidence_id": "EV-PDB-9FGX-2",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 3.53
      },
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        "doi": "10.1038/s41589-025-01972-7",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9FGX"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "cryoem",
      "title": "Cryo-EM structure of Lysozyme homo-dimer assembled by homo Di-Gluebody"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1IE3",
          "A1IE4",
          "CL",
          "NA",
          "VVB"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9FMY",
      "evidence_id": "EV-PDB-9FMY-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.09
      },
      "provenance": {
        "deposit_id": "9FMY",
        "doi": "10.1039/D4QI01528B",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9FMY"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct of bis(maltolato)oxidovanadium(IV) with lysozyme upon the breakage of the maltolate ring"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1IMF",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9GI7",
      "evidence_id": "EV-PDB-9GI7-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
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        "unit": "Å",
        "value": 1.76
      },
      "provenance": {
        "deposit_id": "9GI7",
        "doi": "10.1002/anie.202423078",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9GI7"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg-White Lysozyme (HEWL) complexed with a Lindqvist-type hexavanadate (V6-OH) polyoxometalate"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1IOM",
          "ACT",
          "CL",
          "NA",
          "VVB"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9GOG",
      "evidence_id": "EV-PDB-9GOG-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.24
      },
      "provenance": {
        "deposit_id": "9GOG",
        "doi": "10.1016/j.jinorgbio.2024.112787",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9GOG"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of lysozyme obtained upon reaction with the dioxidovanadium(V) complex with furan-2-carboxylic acid (3-ethoxy-2-hydroxybenzylidene)hydrazide"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1ION",
          "ACT",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9GOK",
      "evidence_id": "EV-PDB-9GOK-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.18
      },
      "provenance": {
        "deposit_id": "9GOK",
        "doi": "10.1016/j.jinorgbio.2024.112787",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9GOK"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of lysozyme obtained upon reaction with the dioxidovanadium(V) complex with (E)-N'-(1-(2-hydroxy-5-methoxyphenyl)ethylidene)furan-2-carbohydrazide)"
    },
    {
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        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9H3E",
      "evidence_id": "EV-PDB-9H3E-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.5
      },
      "provenance": {
        "deposit_id": "9H3E",
        "doi": "10.1002/2211-5463.13932",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9H3E"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg white lysozyme crystallization and structure determination at room temperature in the CrystalChip"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1ISW",
          "CL",
          "EDO",
          "IMD",
          "NA",
          "PEG"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 5.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9H7W",
      "evidence_id": "EV-PDB-9H7W-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
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        "unit": "Å",
        "value": 1.13
      },
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        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9H7W"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen Egg White Lysozyme in Complex with Imidizole"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "EDO",
          "GTQ"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9HC2",
      "evidence_id": "EV-PDB-9HC2-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 1.27
      },
      "provenance": {
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        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9HC2"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Crystal structure of Lysozyme in complex with Gentisic Acid"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "ACT",
          "CL",
          "IOD",
          "NH3",
          "PT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9HLK",
      "evidence_id": "EV-PDB-9HLK-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.96
      },
      "provenance": {
        "deposit_id": "9HLK",
        "doi": "10.1021/acs.inorgchem.4c05424",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9HLK"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of the diiodido analogue of picoplatin with lysozyme (structure A)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "IOD",
          "NH3",
          "PT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9HMQ",
      "evidence_id": "EV-PDB-9HMQ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.25
      },
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        "deposit_id": "9HMQ",
        "doi": "10.1021/acs.inorgchem.4c05424",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9HMQ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-structure of the adduct formed upon reaction of the diiodido analogue of picoplatin with lysozyme (structure C)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1IXG",
          "MES",
          "SO4"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 6.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9HRU",
      "evidence_id": "EV-PDB-9HRU-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.88
      },
      "provenance": {
        "deposit_id": "9HRU",
        "doi": "10.1021/jacs.5c08121",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9HRU"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "The Lysozyme - pctx complex in space group P3121"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1IXJ",
          "ACT",
          "CL",
          "DMS",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9HTI",
      "evidence_id": "EV-PDB-9HTI-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.17
      },
      "provenance": {
        "deposit_id": "9HTI",
        "doi": "10.1039/d5sc05555e",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9HTI"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Adduct formed during the incubation of dichloro(3-benzylbenzoselenazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1IXK",
          "ACT",
          "CL",
          "DMS",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9HTJ",
      "evidence_id": "EV-PDB-9HTJ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.49
      },
      "provenance": {
        "deposit_id": "9HTJ",
        "doi": "10.1039/d5sc05555e",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9HTJ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Adduct formed during the incubation of dichloro(3-benzylbenzothiazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 23.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I6K",
      "evidence_id": "EV-PDB-9I6K-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
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        "deposit_id": "9I6K",
        "doi": "10.1038/s41598-025-25449-8",
        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I6K"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure at 85% relative humidity"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 23.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I6N",
      "evidence_id": "EV-PDB-9I6N-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "9I6N",
        "doi": "10.1038/s41598-025-25449-8",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I6N"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure collected at EuXFEL SPB/SFX with HVE injection method"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 8.0,
        "salt_mM": null,
        "temperature_c": 23.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I6P",
      "evidence_id": "EV-PDB-9I6P-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "9I6P",
        "doi": "10.1038/s41598-025-25449-8",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I6P"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure embedded in LCP medium at 85% relative humidity"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "A1H8D",
          "A1ICR",
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": 36.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I8L",
      "evidence_id": "EV-PDB-9I8L-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.831
      },
      "provenance": {
        "deposit_id": "9I8L",
        "doi": "10.1002/chem.202500488",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I8L"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of a polyoxidovanadate/lysozyme adduct obtained when the protein is treated with [VIVO(acac)2</sub>] at 310 K"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9IG6",
      "evidence_id": "EV-PDB-9IG6-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.8
      },
      "provenance": {
        "deposit_id": "9IG6",
        "doi": "10.1107/S2059798325011258",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9IG6"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "microed",
      "title": "Hen egg-white lysozyme structure determined by 3DED/MicroED on a 200 keV microscope"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9J0M",
      "evidence_id": "EV-PDB-9J0M-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.",
          "rule": "hewl-fibril-structures",
          "state_id": "HEWL-fibril",
          "who": "rule:hewl-fibril-structures"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 3.21
      },
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        "deposit_id": "9J0M",
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        "licence": "CC0 1.0 (wwPDB archive data)",
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9J0M"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "cryoem",
      "title": "Cryo-EM Structure of Lysozyme Type 2 Amyloid Fibrils"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 25.35
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9K9Z",
      "evidence_id": "EV-PDB-9K9Z-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.8
      },
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        "deposit_id": "9K9Z",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9K9Z"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Room-temperature structure of lysozyme determined by serial synchrotron crystallography (MOSFLM)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9KJ7",
      "evidence_id": "EV-PDB-9KJ7-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.3
      },
      "provenance": {
        "deposit_id": "9KJ7",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9KJ7"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Real-space refinement for the hen egg-white lysozyme structure"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9L71",
      "evidence_id": "EV-PDB-9L71-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.0
      },
      "provenance": {
        "deposit_id": "9L71",
        "doi": "10.1080/07391102.2025.2475230",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9L71"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL crystal soaked in buffer of pH12.0"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 25.35
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9L9R",
      "evidence_id": "EV-PDB-9L9R-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.45
      },
      "provenance": {
        "deposit_id": "9L9R",
        "doi": "10.3390/cryst15020104",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9L9R"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Room-temperature structure of lysozyme determined by serial synchrotron crystallography"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9LMK",
      "evidence_id": "EV-PDB-9LMK-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.5
      },
      "provenance": {
        "deposit_id": "9LMK",
        "doi": "10.3390/cryst15020185",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9LMK"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Room temperature structure of lysozyme by serial synchrotron crystallography (XDS)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "branched: N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "HEN EGG WHITE LYSOZYME (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9LYZ",
      "evidence_id": "EV-PDB-9LYZ-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.5
      },
      "provenance": {
        "deposit_id": "9LYZ",
        "doi": "10.1038/282875a0",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9LYZ"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-RAY CRYSTALLOGRAPHY OF THE BINDING OF THE BACTERIAL CELL WALL TRISACCHARIDE NAM-NAG-NAM TO LYSOZYME"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9LML",
      "evidence_id": "EV-PDB-9LML-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.6
      },
      "provenance": {
        "deposit_id": "9LML",
        "doi": "10.3390/cryst15020185",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9LML"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Room temperature structure of lysozyme by serial synchrotron crystallography (MOSFLM)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains P)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9L1L",
      "evidence_id": "EV-PDB-9L1L-5",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "unit": "Å",
        "value": 3.09
      },
      "provenance": {
        "deposit_id": "9L1L",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9L1L"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "cryoem",
      "title": "Structure of anti-HEL AiTab"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9KOT",
      "evidence_id": "EV-PDB-9KOT-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.5
      },
      "provenance": {
        "deposit_id": "9KOT",
        "doi": "10.1080/07391102.2025.2475230",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9KOT"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEWL crystal soaked in buffer of pH2.0"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": 25.35
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9KA0",
      "evidence_id": "EV-PDB-9KA0-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.8
      },
      "provenance": {
        "deposit_id": "9KA0",
        "doi": null,
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9KA0"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Room-temperature structure of lysozyme determined by serial synchrotron crystallography (XGANDALF)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9J0L",
      "evidence_id": "EV-PDB-9J0L-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.",
          "rule": "hewl-fibril-structures",
          "state_id": "HEWL-fibril",
          "who": "rule:hewl-fibril-structures"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
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        "unit": "Å",
        "value": 2.29
      },
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        "deposit_id": "9J0L",
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        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9J0L"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "cryoem",
      "title": "Cryo-EM Structure of Lysozyme Type 1 Amyloid Fibrils"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 23.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I6O",
      "evidence_id": "EV-PDB-9I6O-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "9I6O",
        "doi": "10.1038/s41598-025-25449-8",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I6O"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure embedded in LCP medium at 95% relative humidity"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 23.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I6M",
      "evidence_id": "EV-PDB-9I6M-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "9I6M",
        "doi": "10.1038/s41598-025-25449-8",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I6M"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure at 65% relative humidity"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 23.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I6L",
      "evidence_id": "EV-PDB-9I6L-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "9I6L",
        "doi": "10.1038/s41598-025-25449-8",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I6L"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure at 75% relative humidity"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "EDO",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 23.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9I6J",
      "evidence_id": "EV-PDB-9I6J-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.7
      },
      "provenance": {
        "deposit_id": "9I6J",
        "doi": "10.1038/s41598-025-25449-8",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9I6J"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Hen egg-white lysozyme structure embedded in LCP medium at 95% relative humidity"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "IOD",
          "PT"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 7.0,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains AAA)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9HMK",
      "evidence_id": "EV-PDB-9HMK-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.48
      },
      "provenance": {
        "deposit_id": "9HMK",
        "doi": "10.1021/acs.inorgchem.4c05424",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9HMK"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "X-ray structure of the adduct formed upon reaction of the diiodido analogue of picoplatin with lysozyme (structure B)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A,B)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9GYH",
      "evidence_id": "EV-PDB-9GYH-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 1.6
      },
      "provenance": {
        "deposit_id": "9GYH",
        "doi": "10.1107/S2053230X2500010X",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9GYH"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "HEW Lysozyme with His 15 functionalized with iodoacetamide"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "IMD",
          "NA",
          "RE",
          "REI",
          "VHL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": 37.0
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9GHX",
      "evidence_id": "EV-PDB-9GHX-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.19
      },
      "provenance": {
        "deposit_id": "9GHX",
        "doi": "10.1039/d4cc04245j",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9GHX"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Lysozyme covalently bound to fac-[Re(CO)3-imidazole] complex, incubated for 112 weeks. Data collection done at mammalian body temperature."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": -193.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9GCV",
      "evidence_id": "EV-PDB-9GCV-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
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        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.703
      },
      "provenance": {
        "deposit_id": "9GCV",
        "doi": "10.1107/S2059798324008659",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9GCV"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Identification of chloride ions in lysozyme at long wavelengths"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA",
          "NDG"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9FUE",
      "evidence_id": "EV-PDB-9FUE-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.05
      },
      "provenance": {
        "deposit_id": "9FUE",
        "doi": "10.1038/s42004-024-01404-y",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9FUE"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Serial microseconds crystallography at ID29 using fixed-target (Si Chip): Lysozyme - with ligand GlcNAc"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
        "labels": []
      },
      "data_format": "mmCIF + structure factors",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9FUD",
      "evidence_id": "EV-PDB-9FUD-1",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
        "uncertainty": null,
        "unit": "Å",
        "value": 2.05
      },
      "provenance": {
        "deposit_id": "9FUD",
        "doi": "10.1038/s42004-024-01404-y",
        "licence": "CC0 1.0 (wwPDB archive data)",
        "retrieved": "2026-10-19",
        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9FUD"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
      "title": "Serial microseconds crystallography at ID29 using fixed-target (Si Chip): Lysozyme - without ligand GlcNAc (apo)"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": null,
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "GOL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": null,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C (chains D)",
        "labels": []
      },
      "data_format": "mmCIF + EMDB map",
      "data_level": "processed",
      "data_link": "https://www.rcsb.org/structure/9FGY",
      "evidence_id": "EV-PDB-9FGY-2",
      "mappings": [
        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
          "rule": "hewl-structures-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-structures-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "resolution",
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        }
      ],
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      },
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    },
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          "CL",
          "NA"
        ],
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        "temperature_c": 26.85
      },
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      },
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        {
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        }
      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 26.85
      },
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      },
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        {
          "confidence": "medium",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "NA"
        ],
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        "salt_mM": null,
        "temperature_c": 26.85
      },
      "construct": {
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      },
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        {
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        }
      ],
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      },
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        "url": "https://www.rcsb.org/structure/9P63"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
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        }
      ],
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      },
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        "url": "https://www.rcsb.org/structure/9P5B"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
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        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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        }
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      },
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      },
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      "source_kind": "deposit",
      "technique": "microed",
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    },
    {
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          "NA",
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        ],
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        "temperature_c": -173.15
      },
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      "evidence_id": "EV-PDB-9MP8-1",
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        }
      ],
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    },
    {
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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      "source_kind": "deposit",
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          "NDG"
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "technique": "xray",
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        "temperature_c": -173.15
      },
      "construct": {
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      "data_level": "processed",
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    },
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          "CL",
          "PEG"
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        "temperature_c": 24.85
      },
      "construct": {
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      },
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    },
    {
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          "NA",
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        "temperature_c": 24.85
      },
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      },
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        "url": "https://www.rcsb.org/structure/9RRL"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "NA"
        ],
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        "temperature_c": 19.85
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
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      },
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        "source": "RCSB PDB",
        "url": "https://www.rcsb.org/structure/9RV6"
      },
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      "source_kind": "deposit",
      "technique": "xray",
      "title": "5 micrometer HEWL crystals solved at room-temperature using fixed-target serial crystallography."
    },
    {
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          "CL",
          "NA"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
        "ph": 3.0,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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        {
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        }
      ],
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    },
    {
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          "NA"
        ],
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        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      },
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        {
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        }
      ],
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        "source": "RCSB PDB",
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      "reader": null,
      "source_kind": "deposit",
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    },
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          "A1JKF",
          "MLI",
          "NA"
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        }
      ],
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      },
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        "url": "https://www.rcsb.org/structure/9RZR"
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "CL",
          "NA"
        ],
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
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        {
          "confidence": "medium",
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        }
      ],
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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          "A1JKC"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
      "construct": {
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      },
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        {
          "confidence": "medium",
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        }
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      },
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      "technique": "xray",
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    },
    {
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          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 21.85
      },
      "construct": {
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        "labels": []
      },
      "data_format": "mmCIF + structure factors",
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      "data_link": "https://www.rcsb.org/structure/9SM9",
      "evidence_id": "EV-PDB-9SM9-1",
      "mappings": [
        {
          "confidence": "medium",
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          "who": "rule:hewl-structures-native"
        }
      ],
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      "source_kind": "deposit",
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    },
    {
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        ],
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        "temperature_c": 21.85
      },
      "construct": {
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      },
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          "confidence": "medium",
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        "url": "https://www.rcsb.org/structure/9SMC"
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      "technique": "xray",
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    {
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        "environment": "in_vitro",
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          "CL"
        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "salt_mM": null,
        "temperature_c": 24.85
      },
      "construct": {
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      },
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      "evidence_id": "EV-PDB-9TEK-1",
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        "temperature_c": 19.85
      },
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      },
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    },
    {
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          "NA",
          "NDG"
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        "ph": null,
        "salt_mM": null,
        "temperature_c": 19.85
      },
      "construct": {
        "description": "Lysozyme C (chains A)",
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      },
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          "confidence": "medium",
          "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.",
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      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        "temperature_c": 19.85
      },
      "construct": {
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      "technique": "xray",
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    {
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          "NDG"
        ],
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        "temperature_c": 19.85
      },
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      "source_kind": "deposit",
      "technique": "xray",
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    },
    {
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        ],
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    {
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        "temperature_c": 24.85
      },
      "construct": {
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      },
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        {
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          "NA",
          "NDG"
        ],
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        "temperature_c": 19.85
      },
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      },
      "data_format": "mmCIF + structure factors",
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      ],
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      },
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        ],
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      },
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        "temperature_c": -173.15
      },
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          "CL",
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        "salt_mM": null,
        "temperature_c": -173.15
      },
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      },
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        ],
        "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.",
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        "temperature_c": 19.85
      },
      "construct": {
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      "evidence_id": "EV-PDB-9RVO-1",
      "mappings": [
        {
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      "technique": "xray",
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    {
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        ],
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        "salt_mM": null,
        "temperature_c": 36.85
      },
      "construct": {
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      },
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    },
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        "temperature_c": 36.85
      },
      "construct": {
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        "temperature_c": -173.15
      },
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      },
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      },
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      },
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        "temperature_c": -173.15
      },
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      },
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    {
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        ],
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        "temperature_c": 24.85
      },
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        ],
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        "temperature_c": null
      },
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        "applied_force_pn": null,
        "buffer": "20 mM Sodium Acetate/HEPES",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.79 nm.",
        "ph": 6.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDA96/",
      "evidence_id": "EV-SASBDB-SASDA96",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": null,
        "unit": "nm",
        "value": 1.5
      },
      "provenance": {
        "deposit_id": "SASDA96",
        "doi": "10.1038/nmeth.3358",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDA96/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Correlation Map, a goodness-of-fit test for one-dimensional X-ray scattering spectra."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM Sodium Acetate",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDAC2/",
      "evidence_id": "EV-SASBDB-SASDAC2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": null,
        "unit": "nm",
        "value": 1.47
      },
      "provenance": {
        "deposit_id": "SASDAC2",
        "doi": null,
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDAC2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Standard proteins"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM Sodium Acetate",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDAG2/",
      "evidence_id": "EV-SASBDB-SASDAG2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": null,
        "unit": "nm",
        "value": 1.45
      },
      "provenance": {
        "deposit_id": "SASDAG2",
        "doi": null,
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDAG2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Standard proteins"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM Sodium Acetate pH 4.0, 50 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDCK8/",
      "evidence_id": "EV-SASBDB-SASDCK8",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.03,
        "unit": "nm",
        "value": 1.41
      },
      "provenance": {
        "deposit_id": "SASDCK8",
        "doi": null,
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDCK8/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "WAXS benchmark on standard proteins"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM sodium acetate, 150 mM NaCl, 100 mM 5-methyl uridine",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.2 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 25.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDJH3/",
      "evidence_id": "EV-SASBDB-SASDJH3",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.025,
        "unit": "nm",
        "value": 1.45
      },
      "provenance": {
        "deposit_id": "SASDJH3",
        "doi": "10.1107/S2059798320010700",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDJH3/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Improving data quality and expanding BioSAXS experiments to low-molecular-weight and low-concentration protein samples."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "0.2 M glycine-HCl, 80 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "partner: Fe3O4 nanoparticles; nominal diameter 10 nm (hydrodynamic diameter)"
        ],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 70 nm.",
        "ph": 2.2,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 10 nm (hydrodynamic diameter)",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDM44/",
      "evidence_id": "EV-SASBDB-SASDM44",
      "mappings": [],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.104,
        "unit": "nm",
        "value": 22.305
      },
      "provenance": {
        "deposit_id": "SASDM44",
        "doi": "10.3390/molecules26164864",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDM44/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "0.2 M glycine-HCl, 80 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "partner: Fe3O4 nanoparticles; nominal diameter 30 nm (hydrodynamic diameter)"
        ],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 95 nm.",
        "ph": 2.2,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 30 nm (hydrodynamic diameter)",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDM54/",
      "evidence_id": "EV-SASBDB-SASDM54",
      "mappings": [],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.248,
        "unit": "nm",
        "value": 22.537
      },
      "provenance": {
        "deposit_id": "SASDM54",
        "doi": "10.3390/molecules26164864",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDM54/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "0.2 M glycine-HCl, 80 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "partner: Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)"
        ],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 90 nm.",
        "ph": 2.2,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDM64/",
      "evidence_id": "EV-SASBDB-SASDM64",
      "mappings": [],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.226,
        "unit": "nm",
        "value": 23.642
      },
      "provenance": {
        "deposit_id": "SASDM64",
        "doi": "10.3390/molecules26164864",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDM64/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "0.2 M glycine-HCl, 80 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "partner: Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)"
        ],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 75 nm.",
        "ph": 2.2,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDM74/",
      "evidence_id": "EV-SASBDB-SASDM74",
      "mappings": [],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.169,
        "unit": "nm",
        "value": 30.97
      },
      "provenance": {
        "deposit_id": "SASDM74",
        "doi": "10.3390/molecules26164864",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDM74/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "100 mM HEPES pH 7.5, 20 %(v/v) jeffamine M-600",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.",
        "ph": 7.5,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDM79/",
      "evidence_id": "EV-SASBDB-SASDM79",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.015,
        "unit": "nm",
        "value": 1.75
      },
      "provenance": {
        "deposit_id": "SASDM79",
        "doi": "10.32607/actanaturae.11815",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDM79/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "The Relationship of Precursor Cluster Concentration in a Saturated Crystallization Solution to Long-Range Order During the Transition to the Solid Phase."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "100 mM sodium acetate, pH 4.6, 2.0 M sodium formate",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.",
        "ph": 4.6,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDM89/",
      "evidence_id": "EV-SASBDB-SASDM89",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.071,
        "unit": "nm",
        "value": 2.15
      },
      "provenance": {
        "deposit_id": "SASDM89",
        "doi": "10.32607/actanaturae.11815",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDM89/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "The Relationship of Precursor Cluster Concentration in a Saturated Crystallization Solution to Long-Range Order During the Transition to the Solid Phase."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "200 mM K/Na tartrate, 100 mM tri-sodium citrate pH 5.6, 2.0 M ammonium sulfate",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.",
        "ph": 5.6,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDM99/",
      "evidence_id": "EV-SASBDB-SASDM99",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.039,
        "unit": "nm",
        "value": 2.35
      },
      "provenance": {
        "deposit_id": "SASDM99",
        "doi": "10.32607/actanaturae.11815",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDM99/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "The Relationship of Precursor Cluster Concentration in a Saturated Crystallization Solution to Long-Range Order During the Transition to the Solid Phase."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.23 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMC2/",
      "evidence_id": "EV-SASBDB-SASDMC2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.054,
        "unit": "nm",
        "value": 1.322
      },
      "provenance": {
        "deposit_id": "SASDMC2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMC2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.29 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMD2/",
      "evidence_id": "EV-SASBDB-SASDMD2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.03,
        "unit": "nm",
        "value": 1.396
      },
      "provenance": {
        "deposit_id": "SASDMD2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMD2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.52 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDME2/",
      "evidence_id": "EV-SASBDB-SASDME2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.027,
        "unit": "nm",
        "value": 1.418
      },
      "provenance": {
        "deposit_id": "SASDME2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDME2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.95 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMF2/",
      "evidence_id": "EV-SASBDB-SASDMF2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.029,
        "unit": "nm",
        "value": 1.44
      },
      "provenance": {
        "deposit_id": "SASDMF2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMF2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.58 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMG2/",
      "evidence_id": "EV-SASBDB-SASDMG2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.046,
        "unit": "nm",
        "value": 1.454
      },
      "provenance": {
        "deposit_id": "SASDMG2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMG2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.19 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMH2/",
      "evidence_id": "EV-SASBDB-SASDMH2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.04,
        "unit": "nm",
        "value": 1.397
      },
      "provenance": {
        "deposit_id": "SASDMH2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMH2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.19 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMJ2/",
      "evidence_id": "EV-SASBDB-SASDMJ2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.026,
        "unit": "nm",
        "value": 1.398
      },
      "provenance": {
        "deposit_id": "SASDMJ2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMJ2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "0.2 M glycine-HCl, 80 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 120 nm.",
        "ph": 2.2,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "lysozyme amyloid fibril",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMJ4/",
      "evidence_id": "EV-SASBDB-SASDMJ4",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.131,
        "unit": "nm",
        "value": 30.226
      },
      "provenance": {
        "deposit_id": "SASDMJ4",
        "doi": "10.1002/bip.23342",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMJ4/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Effect of the concentration of protein and nanoparticles on the structure of biohybrid nanocomposites."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.19 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMK2/",
      "evidence_id": "EV-SASBDB-SASDMK2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.101,
        "unit": "nm",
        "value": 1.389
      },
      "provenance": {
        "deposit_id": "SASDMK2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMK2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.19 nm.",
        "ph": 3.8,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDML2/",
      "evidence_id": "EV-SASBDB-SASDML2",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.026,
        "unit": "nm",
        "value": 1.398
      },
      "provenance": {
        "deposit_id": "SASDML2",
        "doi": "10.1080/07391102.2021.1977704",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDML2/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "0.2 M glycine-HCl, 80 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [
          "partner: Fe3O4 nanoparticles; radius 5.6 nm (AFM based)"
        ],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 80 nm.",
        "ph": 2.2,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; radius 5.6 nm (AFM based)",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDML4/",
      "evidence_id": "EV-SASBDB-SASDML4",
      "mappings": [],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.014,
        "unit": "nm",
        "value": 29.366
      },
      "provenance": {
        "deposit_id": "SASDML4",
        "doi": "10.1002/bip.23342",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDML4/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Effect of the concentration of protein and nanoparticles on the structure of biohybrid nanocomposites."
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "0.2 M glycine-HCl, 80 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 80 nm.",
        "ph": 2.2,
        "salt_mM": null,
        "temperature_c": 20.0
      },
      "construct": {
        "description": "lysozyme amyloid fibril",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDMY3/",
      "evidence_id": "EV-SASBDB-SASDMY3",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.08,
        "unit": "nm",
        "value": 38.397
      },
      "provenance": {
        "deposit_id": "SASDMY3",
        "doi": "10.3390/molecules26164864",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDMY3/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "50 mM sodium citrate, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.8 nm.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDPT4/",
      "evidence_id": "EV-SASBDB-SASDPT4",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.054,
        "unit": "nm",
        "value": 1.464
      },
      "provenance": {
        "deposit_id": "SASDPT4",
        "doi": "10.1107/S2059798322009184",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDPT4/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "50 mM sodium citrate, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 3.8 nm.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDPV4/",
      "evidence_id": "EV-SASBDB-SASDPV4",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.052,
        "unit": "nm",
        "value": 1.244
      },
      "provenance": {
        "deposit_id": "SASDPV4",
        "doi": "10.1107/S2059798322009184",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDPV4/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "50 mM sodium citrate, 150 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.8 nm.",
        "ph": 4.5,
        "salt_mM": null,
        "temperature_c": null
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDPZ4/",
      "evidence_id": "EV-SASBDB-SASDPZ4",
      "mappings": [
        {
          "confidence": "low",
          "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.",
          "rule": "hewl-saxs-native",
          "state_id": "HEWL-native",
          "who": "rule:hewl-saxs-native"
        }
      ],
      "molecule_id": "P00698",
      "observable": {
        "type": "radius_of_gyration",
        "uncertainty": 0.012,
        "unit": "nm",
        "value": 1.428
      },
      "provenance": {
        "deposit_id": "SASDPZ4",
        "doi": "10.1107/S2059798322009184",
        "licence": "CC BY 4.0 (verify)",
        "retrieved": "2026-10-19",
        "source": "SASBDB",
        "url": "https://www.sasbdb.org/data/SASDPZ4/"
      },
      "reader": null,
      "source_kind": "deposit",
      "technique": "saxs_sans",
      "title": "A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking"
    },
    {
      "conditions": {
        "applied_force_pn": null,
        "buffer": "40 mM sodium acetate, 50 mM NaCl",
        "environment": "in_vitro",
        "ions": [],
        "ligands": [],
        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.64 nm.",
        "ph": 4.0,
        "salt_mM": null,
        "temperature_c": 10.0
      },
      "construct": {
        "description": "Lysozyme C",
        "labels": []
      },
      "data_format": "scattering curve",
      "data_level": "processed",
      "data_link": "https://www.sasbdb.org/data/SASDRM8/",
      "evidence_id": "EV-SASBDB-SASDRM8",
      "mappings": [
        {
          "confidence": "low",
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      ],
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        "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.2 nm.",
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      "description": "Native fold of hen lysozyme, as in 193L (tetragonal, 1.33 Å).",
      "family_label": null,
      "molecule_id": "P00698",
      "name": "native fold",
      "parent_state": null,
      "population": null,
      "provenance": {
        "deposit_id": null,
        "doi": null,
        "licence": "Project licence (pending decision)",
        "retrieved": "2026-10-19",
        "source": "Conformome curation (P00698.yaml)",
        "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P00698.yaml"
      },
      "representative_model": "HEWL-native-cif",
      "secondary_structure": null,
      "state_id": "HEWL-native",
      "status": "draft"
    },
    {
      "assumptions": [
        "Treated as a single ensemble; residual structure and intermediates are not resolved.",
        "Defined by indirect measurements (denaturation, NMR of denatured samples, force spectroscopy); no model is exported."
      ],
      "basis": "inferred",
      "description": "Unfolded ensemble reached by denaturant, temperature or force. No observed structure.",
      "family_label": null,
      "molecule_id": "P00698",
      "name": "unfolded",
      "parent_state": null,
      "population": null,
      "provenance": {
        "deposit_id": null,
        "doi": null,
        "licence": "Project licence (pending decision)",
        "retrieved": "2026-10-19",
        "source": "Conformome curation (P00698.yaml)",
        "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P00698.yaml"
      },
      "representative_model": null,
      "secondary_structure": null,
      "state_id": "HEWL-unfolded",
      "status": "draft"
    },
    {
      "assumptions": [],
      "basis": "observed",
      "description": "Cross-beta amyloid fibril of hen lysozyme, as in 9J0L (type 1 fibril, cryo-EM, 2.29 Å). Types 1 and 2 (9J0M) and the heat-irreversible fibril (8QV8) are polymorphs and are pooled in this one state.",
      "family_label": null,
      "molecule_id": "P00698",
      "name": "amyloid fibril",
      "parent_state": null,
      "population": null,
      "provenance": {
        "deposit_id": null,
        "doi": null,
        "licence": "Project licence (pending decision)",
        "retrieved": "2026-10-19",
        "source": "Conformome curation (P00698.yaml)",
        "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P00698.yaml"
      },
      "representative_model": "HEWL-fibril-cif",
      "secondary_structure": null,
      "state_id": "HEWL-fibril",
      "status": "draft"
    }
  ],
  "transitions": []
}
