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}, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human Cu-Zn superoxide dismutase mutant G85R in space group I212121" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZKY", "evidence_id": "EV-PDB-2ZKY-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4 }, "provenance": { "deposit_id": "2ZKY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": 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null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ECU", "evidence_id": "EV-PDB-3ECU-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9 }, "provenance": { "deposit_id": "3ECU", "doi": "10.1073/pnas.0809845106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ECU" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human apo Cu,Zn Superoxide Dismutase (SOD1)" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; 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"molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.453 }, "provenance": { "deposit_id": "3LTV", "doi": "10.1016/j.abb.2010.08.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LTV" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Mouse-human sod1 chimera" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CU1", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,D,E,F,G,H,I,J,K,L,M)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3T5W", "evidence_id": "EV-PDB-3T5W-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8 }, "provenance": { "deposit_id": "3T5W", "doi": "10.1042/BSR20120029", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3T5W" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "2ME modified human SOD1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "5UD", "ACT", "CU", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A7S", "evidence_id": "EV-PDB-4A7S-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.06 }, "provenance": { "deposit_id": "4A7S", "doi": "10.1038/NCOMMS2750", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A7S" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CU", "LDP", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "SUPEROXIDE DISMUTASE [CU-ZN] (chains A,F)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A7V", "evidence_id": "EV-PDB-4A7V-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.0 }, "provenance": { "deposit_id": "4A7V", "doi": "10.1038/NCOMMS2750", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A7V" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MCM", "evidence_id": "EV-PDB-4MCM-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2 }, "provenance": { "deposit_id": "4MCM", "doi": "10.1074/jbc.M114.588798", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MCM" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Human SOD1 C57S Mutant, As-isolated" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "GVTGIAQ segment from Superoxide dismutase [Cu-Zn] (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NIP", "evidence_id": "EV-PDB-4NIP-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9 }, "provenance": { "deposit_id": "4NIP", "doi": "10.1073/pnas.1320786110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NIP" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "GVIGIAQ segment 147-153 from Human Superoxide Dismutase" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "9JK", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.75, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,F)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5O3Y", "evidence_id": "EV-PDB-5O3Y-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3 }, "provenance": { "deposit_id": "5O3Y", "doi": "10.1038/s41467-018-04114-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5O3Y" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "SOD1 bound to Ebsulfur" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "9JT", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,F)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5O40", "evidence_id": "EV-PDB-5O40-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5 }, "provenance": { "deposit_id": "5O40", "doi": "10.1038/s41467-018-04114-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5O40" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "SOD1 bound to Ebselen" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GOL", "MLI" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WOR", "evidence_id": "EV-PDB-5WOR-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77 }, "provenance": { "deposit_id": "5WOR", "doi": "10.1002/pro.3391", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WOR" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Corkscrew assembly of SOD1 residues 28-38 with familial mutation G37R" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "TFA" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WMJ", "evidence_id": "EV-PDB-5WMJ-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4 }, "provenance": { "deposit_id": "5WMJ", "doi": "10.1002/pro.3391", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WMJ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "KVWGSI segment from Superoxide Dismutase 1,residues 30-35" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,C)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5U9M", "evidence_id": "EV-PDB-5U9M-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35 }, "provenance": { "deposit_id": "5U9M", "doi": "10.1074/jbc.M117.775981", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5U9M" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Copper-Zinc Superoxide Dismutase is Activated through a Sulfenic Acid Intermediate at a Copper-ion Entry Site" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CU", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5K02", "evidence_id": "EV-PDB-5K02-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99 }, "provenance": { "deposit_id": "5K02", "doi": "10.1016/j.str.2016.08.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5K02" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Structure of human SOD1 with T2D mutation" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] (chains A,B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J0G", "evidence_id": "EV-PDB-5J0G-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5 }, "provenance": { "deposit_id": "5J0G", "doi": "10.1021/jacs.6b05151", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J0G" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GOL" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] (chains A,B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J0F", "evidence_id": "EV-PDB-5J0F-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.25 }, "provenance": { "deposit_id": "5J0F", "doi": "10.1021/jacs.6b05151", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J0F" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P4/5" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] (chains A,B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J0C", "evidence_id": "EV-PDB-5J0C-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6 }, "provenance": { "deposit_id": "5J0C", "doi": "10.1021/jacs.6b05151", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J0C" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn] (chains A,B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J07", "evidence_id": "EV-PDB-5J07-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0 }, "provenance": { "deposit_id": "5J07", "doi": "10.1021/jacs.6b05151", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J07" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IIW", "evidence_id": "EV-PDB-5IIW-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0 }, "provenance": { "deposit_id": "5IIW", "doi": "10.1073/pnas.1705091114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IIW" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Corkscrew assembly of SOD1 residues 28-38 without potassium iodide" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GOL", "IOD" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DLI", "evidence_id": "EV-PDB-5DLI-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1 }, "provenance": { "deposit_id": "5DLI", "doi": "10.1073/pnas.1705091114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DLI" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Corkscrew assembly of SOD1 residues 28-38" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XCR", "evidence_id": "EV-PDB-4XCR-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.602 }, "provenance": { "deposit_id": "4XCR", "doi": "10.1073/pnas.1511308112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XCR" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CU", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,C,D,E,F,G,H,I,J)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OH2", "evidence_id": "EV-PDB-4OH2-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.384 }, "provenance": { "deposit_id": "4OH2", "doi": "10.1016/j.bpj.2014.07.068", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OH2" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Cu/Zn Superoxide Dismutase I149T" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "GVTGIAQ segment from Superoxide dismutase [Cu-Zn] (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NIO", "evidence_id": "EV-PDB-4NIO-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3 }, "provenance": { "deposit_id": "4NIO", "doi": "10.1073/pnas.1320786110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NIO" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "DSVISLS segment from Superoxide dismutase [Cu-Zn] (chains A)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": 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"construct": { "description": "Monomeric Human Cu,Zn Superoxide dismutase (chains A)", "labels": [] }, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CJW", "evidence_id": "EV-PDB-7CJW-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "structure", "uncertainty": null, "unit": null, "value": null }, "provenance": { "deposit_id": "7CJW", "doi": "10.1021/acs.jpcb.0c11162", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CJW" }, "reader": null, "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "Q7T", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains AAA,BBB)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z4O", "evidence_id": "EV-PDB-6Z4O-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4 }, "provenance": { "deposit_id": "6Z4O", "doi": "10.1016/j.ebiom.2020.102980", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z4O" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 1 in P21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "Q8H", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains AAA,BBB)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z4L", "evidence_id": "EV-PDB-6Z4L-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6 }, "provenance": { "deposit_id": "6Z4L", "doi": "10.1016/j.ebiom.2020.102980", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z4L" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 9 in P21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CL", "Q7N", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains AAA,BBB)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z4K", "evidence_id": "EV-PDB-6Z4K-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45 }, "provenance": { "deposit_id": "6Z4K", "doi": "10.1016/j.ebiom.2020.102980", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z4K" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 6 in P21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CL", "Q7W", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains AAA,BBB)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z4J", "evidence_id": "EV-PDB-6Z4J-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55 }, "provenance": { "deposit_id": "6Z4J", "doi": "10.1016/j.ebiom.2020.102980", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z4J" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 5 in P21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ACT", "Q85", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains AAA,FFF)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z4I", "evidence_id": "EV-PDB-6Z4I-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6 }, "provenance": { "deposit_id": "6Z4I", "doi": "10.1016/j.ebiom.2020.102980", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z4I" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 3 in P21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "LQW", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains AAA,BBB)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z4H", "evidence_id": "EV-PDB-6Z4H-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95 }, "provenance": { "deposit_id": "6Z4H", "doi": "10.1016/j.ebiom.2020.102980", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z4H" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 2 in P21 space group" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CL", "DMS", "GOL", "LQN", "NA", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,E,F,I,J)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SPK", "evidence_id": "EV-PDB-6SPK-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77 }, "provenance": { "deposit_id": "6SPK", "doi": "10.1038/s42003-020-0826-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SPK" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 6" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "CL", "DMS", "GOL", "LR2", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,E,F,I,J)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SPJ", "evidence_id": "EV-PDB-6SPJ-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.97 }, "provenance": { "deposit_id": "6SPJ", "doi": "10.1038/s42003-020-0826-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SPJ" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 1" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "LQW", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides 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"ligands": [ "9JT", "DMS", "GOL", "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,C,E,G,J,L)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SPH", "evidence_id": "EV-PDB-6SPH-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25 }, "provenance": { "deposit_id": "6SPH", "doi": "10.1038/s42003-020-0826-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SPH" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 WITH EBSELEN BOND IN 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"source_kind": "deposit", "technique": "xray", "title": "A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 IN C2 SPACE GROUP" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "GOL", "PPI", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,C,E,G,I,K,M,O,Q,S,U,W)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6FP6", "evidence_id": "EV-PDB-6FP6-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0 }, "provenance": { "deposit_id": "6FP6", "doi": "10.1371/journal.pbio.3000141", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6FP6" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains B,D)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6FON", "evidence_id": "EV-PDB-6FON-2", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05 }, "provenance": { "deposit_id": 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"observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55 }, "provenance": { "deposit_id": "6FOL", "doi": "10.1371/journal.pbio.3000141", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6FOL" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase" }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "SO4", "ZN" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,D,F,G,I,K,M,O,Q,S,U,W)", "labels": [] }, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6FOI", "evidence_id": "EV-PDB-6FOI-1", "mappings": [], "molecule_id": "P00441", "observable": { "type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0 }, "provenance": { "deposit_id": "6FOI", "doi": "10.1371/journal.pbio.3000141", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6FOI" }, "reader": null, "source_kind": "deposit", "technique": "xray", "title": "Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated." }, { "conditions": { "applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [ "D7Z" ], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15 }, "construct": { "description": "Superoxide dismutase [Cu-Zn] (chains A,B,D,F)", "labels": [] }, 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