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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3') (chains A); same sequence", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=143D", "evidence_id": "EV-NAKB-143D-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "143D", "doi": "10.1016/0969-2126(93)90015-9", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=143D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF THE HUMAN TELOMERIC REPEAT D(AG3[T2AG3]3) OF THE G-QUADRUPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "K+"}], "ligands": [], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3 (chains A); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=1KF1", "evidence_id": "EV-NAKB-1KF1-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1KF1", "doi": "10.1038/nature755", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=1KF1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure and Packing of Human Telomeric DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA (5'-D(*DAP*(BGM)P*DGP*DGP*DTP*DTP*DAP*(BGM)P*DGP*DGP*DTP*DTP*DAP*(BGM)P*(BGM)P*DGP*DTP*DTP*DAP*(BGM)P*DGP*DG)-3') (chains A); same sequence", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=2E4I", "evidence_id": "EV-NAKB-2E4I-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2E4I", "doi": "10.1111/j.1742-4658.2007.05881.x", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=2E4I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Human Telomeric DNA mixed-parallel/antiparallel quadruplex under Physiological Ionic Conditions Stabilized by Proper Incorporation of 8-Bromoguanosines"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RUL"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "human_telomere_quadruplex (chains A); same sequence", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=2MCC", "evidence_id": "EV-NAKB-2MCC-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2MCC", "doi": null, "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=2MCC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomere sequence"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "K+"}], "ligands": ["BER"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA (22-mer) (chains A); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=3R6R", "evidence_id": "EV-NAKB-3R6R-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "3R6R", "doi": "10.1093/nar/gks1001", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=3R6R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the complex of an intramolecular human telomeric DNA with Berberine formed in K+ solution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "K+"}], "ligands": ["R8G"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Human telomeric repeat sequence (chains A); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=3SC8", "evidence_id": "EV-NAKB-3SC8-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.302}, "provenance": {"deposit_id": "3SC8", "doi": "10.1021/ja2102423", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=3SC8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of an intramolecular human telomeric DNA G-quadruplex bound by the naphthalene diimide BMSG-SH-3"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "K+"}], "ligands": ["0DX"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "human telomeric DNA sequence (chains A); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=3UYH", "evidence_id": "EV-NAKB-3UYH-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "3UYH", "doi": "10.1021/jm301899y", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=3UYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of an intramolecular human telomeric DNA G-quadruplex bound by the naphthalene diimide compound, MM41"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "K+"}], "ligands": ["MMP"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3') (chains A); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=4FXM", "evidence_id": "EV-NAKB-4FXM-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.651}, "provenance": {"deposit_id": "4FXM", "doi": "10.1021/ja3088746", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=4FXM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl mesoporphyrin IX (P21212)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "K+"}], "ligands": ["MMP"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3') (chains A); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=4G0F", "evidence_id": "EV-NAKB-4G0F-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "4G0F", "doi": "10.1021/ja3088746", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=4G0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl mesoporphyrin IX (P6)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "K+"}], "ligands": [], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3') (chains A); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=6IP3", "evidence_id": "EV-NAKB-6IP3-1", "mappings": [], "molecule_id": "DNA-6f16b68e4fba", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "6IP3", "doi": "10.1093/nar/gkz419", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=6IP3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of human telomeric DNA at 1.4 Angstroms resolution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ATP-dependent RNA helicase DDX3X (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5E7J", "evidence_id": "EV-PDB-5E7J-1", "mappings": [], "molecule_id": "O00571", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.23}, "provenance": {"deposit_id": "5E7J", "doi": "10.1074/jbc.M115.700625", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5E7J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ATP-dependent RNA helicase DDX3X (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5E7I", "evidence_id": "EV-PDB-5E7I-1", "mappings": [], "molecule_id": "O00571", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.223}, "provenance": {"deposit_id": "5E7I", "doi": "10.1074/jbc.M115.700625", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5E7I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the active catalytic core of the human DEAD-box protein DDX3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ATP-dependent RNA helicase DDX3X (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PXA", "evidence_id": "EV-PDB-4PXA-1", "mappings": [], "molecule_id": "O00571", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "4PXA", "doi": "10.1016/j.jmb.2015.02.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PXA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DEAD-box RNA helicase DDX3X Cancer-associated mutant D354V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ATP-dependent RNA helicase DDX3X (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PX9", "evidence_id": "EV-PDB-4PX9-1", "mappings": [], "molecule_id": "O00571", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.31}, "provenance": {"deposit_id": "4PX9", "doi": "10.1016/j.jmb.2015.02.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DEAD-box RNA helicase DDX3X Domain 1 with N-terminal ATP-binding Loop"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptide from ATP-dependent RNA helicase DDX3X (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4O2F", "evidence_id": "EV-PDB-4O2F-3", "mappings": [], "molecule_id": "O00571", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.901}, "provenance": {"deposit_id": "4O2F", "doi": "10.4049/jimmunol.1400199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4O2F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A peptide complexed with HLA-B*3901"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CU1", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "SUPEROXIDE DISMUTASE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BA9", "evidence_id": "EV-PDB-1BA9-1", "mappings": [], "molecule_id": "P00441", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BA9", "doi": "10.1021/bi9803473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BA9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THE SOLUTION STRUCTURE OF REDUCED MONOMERIC SUPEROXIDE DISMUTASE, NMR, 36 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CU", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "SUPEROXIDE DISMUTASE (CU-ZN) (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DSW", "evidence_id": "EV-PDB-1DSW-1", "mappings": [], "molecule_id": "P00441", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1DSW", "doi": "10.1007/s007750050353", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DSW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THE SOLUTION STRUCTURE OF A MONOMERIC, REDUCED FORM OF HUMAN COPPER, ZINC SUPEROXIDE DISMUTASE BEARING THE SAME CHARGE AS THE NATIVE PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SUPEROXIDE DISMUTASE (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HL4", "evidence_id": "EV-PDB-1HL4-1", "mappings": [], "molecule_id": "P00441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82}, "provenance": {"deposit_id": "1HL4", "doi": "10.1016/S0022-2836(03)00355-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HL4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The Structure of Apo Type Human Cu, Zn Superoxide Dismutase"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Superoxide dismutase [Cu-Zn] (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XCR", "evidence_id": "EV-PDB-4XCR-1", "mappings": [], "molecule_id": "P00441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.602}, "provenance": {"deposit_id": "4XCR", "doi": "10.1073/pnas.1511308112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XCR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Proto-oncogene tyrosine-protein kinase ABL1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZZP", "evidence_id": "EV-PDB-1ZZP-1", "mappings": [], "molecule_id": "P00519", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1ZZP", "doi": "10.1016/j.molcel.2005.06.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZZP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "ABL TYROSINE KINASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ABL", "evidence_id": "EV-PDB-2ABL-1", "mappings": [], "molecule_id": "P00519", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "2ABL", "doi": "10.1016/S0969-2126(96)00116-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ABL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["STI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Proto-oncogene tyrosine-protein kinase ABL1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2HYY", "evidence_id": "EV-PDB-2HYY-1", "mappings": [{"confidence": "high", "justification": "Human Abl kinase domain with imatinib (STI).", "rule": "curator_assignment", "state_id": "Abl-DFG-out", "who": "curator:draft (unreviewed)"}], "molecule_id": "P00519", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "2HYY", "doi": "10.1107/S0907444906047287", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2HYY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Abl kinase domain in complex with imatinib (STI571, Glivec)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JIN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Proto-oncogene tyrosine-protein kinase ABL1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2HZI", "evidence_id": "EV-PDB-2HZI-1", "mappings": [], "molecule_id": "P00519", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2HZI", "doi": "10.1107/S0907444906047287", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2HZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Abl kinase domain in complex with PD180970"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EY4", "evidence_id": "EV-PDB-1EY4-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1EY4", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EY4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING MUTANT S59A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EY5", "evidence_id": "EV-PDB-1EY5-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1EY5", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EY5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T33V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EY6", "evidence_id": "EV-PDB-1EY6-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "1EY6", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EY6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T41I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EY7", "evidence_id": "EV-PDB-1EY7-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.88}, "provenance": {"deposit_id": "1EY7", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EY7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING MUTANT S128A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EY8", "evidence_id": "EV-PDB-1EY8-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "1EY8", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EY8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING TRIPLE MUTANT P117G/H124L/S128A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EY9", "evidence_id": "EV-PDB-1EY9-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "1EY9", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EY9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING QUADRUPLE MUTANT T41I/P117G/H124L/S128A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EYA", "evidence_id": "EV-PDB-1EYA-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1EYA", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EYA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING QUINTUPLE MUTANT T33V/T41I/P117G/H124L/S128A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EYC", "evidence_id": "EV-PDB-1EYC-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1EYC", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EYC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING QUINTUPLE MUTANT T41I/S59A/P117G/H124L/S128A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EYD", "evidence_id": "EV-PDB-1EYD-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1EYD", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EYD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF WILD-TYPE S. NUCLEASE AT 1.7 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EZ6", "evidence_id": "EV-PDB-1EZ6-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1EZ6", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EZ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING SEXTUPLE MUTANT T33V/T41I/S59A/P117G/H124L/S128A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EZ8", "evidence_id": "EV-PDB-1EZ8-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1EZ8", "doi": "10.1006/jmbi.2000.4140", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EZ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T33V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 44.85}, "construct": {"description": "staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JOQ", "evidence_id": "EV-PDB-1JOQ-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1JOQ", "doi": "10.1023/A:1018350004729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JOQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Ensemble structures for Staphylococcal nuclease-H124L in ternary complex with Ca2+ and thymidine-3',5'-bisphosphate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KAA", "evidence_id": "EV-PDB-1KAA-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1KAA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRESS AND STRAIN IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KAB", "evidence_id": "EV-PDB-1KAB-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1KAB", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KAB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRESS AND STRAIN IN STAPHYLOCOCCAL NUCLEASE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SNP", "evidence_id": "EV-PDB-1SNP-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "1SNP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SNP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN STABILITY IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SNQ", "evidence_id": "EV-PDB-1SNQ-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1SNQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SNQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN STABILITY IN STAPHYLOCOCCAL NUCLEASE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1STN", "evidence_id": "EV-PDB-1STN-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1STN", "doi": "10.1002/prot.340100203", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1STN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE CRYSTAL STRUCTURE OF STAPHYLOCOCCAL NUCLEASE REFINED AT 1.7 ANGSTROMS RESOLUTION"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NSN", "evidence_id": "EV-PDB-1NSN-3", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1NSN", "doi": "10.1006/jmbi.1995.0573", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NSN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE CRYSTAL STRUCTURE OF ANTIBODY N10-STAPHYLOCOCCAL NUCLEASE COMPLEX AT 2.9 ANGSTROMS RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KDC", "evidence_id": "EV-PDB-1KDC-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1KDC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KDC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STABILIZATION OF A STRAINED PROTEIN LOOP CONFORMATION THROUGH PROTEIN ENGINEERING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 44.85}, "construct": {"description": "staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JOR", "evidence_id": "EV-PDB-1JOR-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1JOR", "doi": "10.1023/A:1018350004729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JOR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Ensemble structures for unligated Staphylococcal nuclease-H124L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 44.85}, "construct": {"description": "staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JOO", "evidence_id": "EV-PDB-1JOO-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1JOO", "doi": "10.1023/A:1018350004729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JOO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Averaged structure for unligated Staphylococcal nuclease-H124L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 44.85}, "construct": {"description": "staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JOK", "evidence_id": "EV-PDB-1JOK-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1JOK", "doi": "10.1023/A:1018350004729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JOK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Averaged structure for Staphylococcal nuclease-H124L in ternary complex with Ca2+ and thymidine-3',5'-bisphosphate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1II3", "evidence_id": "EV-PDB-1II3-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "1II3", "doi": "10.1016/j.bpc.2004.02.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1II3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IHZ", "evidence_id": "EV-PDB-1IHZ-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "1IHZ", "doi": "10.1016/j.bpc.2004.02.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of S. nuclease mutant quintuple mutant V23L/V66L/I72L/I92L/V99L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1F2Z", "evidence_id": "EV-PDB-1F2Z-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1F2Z", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1F2Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1F2Y", "evidence_id": "EV-PDB-1F2Y-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1F2Y", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1F2Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1F2M", "evidence_id": "EV-PDB-1F2M-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1F2M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1F2M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "THERMONUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EQV", "evidence_id": "EV-PDB-1EQV-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "1EQV", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIMPLIFICATION OF A PROTEIN LOOP IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ENC", "evidence_id": "EV-PDB-1ENC-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "1ENC", "doi": "10.1021/bi00192a004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ENC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 5.0}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AEX", "evidence_id": "EV-PDB-1AEX-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1AEX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AEX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STAPHYLOCOCCAL NUCLEASE, METHANE THIOL DISULFIDE TO V23C VARIANT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.15, "salt_mM": null, "temperature_c": 5.0}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1A3T", "evidence_id": "EV-PDB-1A3T-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1A3T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1A3T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STAPHYLOCOCCAL NUCLEASE, V23C VARIANT, COMPLEX WITH 2-FLUOROETHANE THIOL AND 3',5'-THYMIDINE DIPHOSPHATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TQO", "evidence_id": "EV-PDB-1TQO-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1TQO", "doi": "10.1016/j.jmb.2004.05.066", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TQO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic Crystal Structure of Staphylococcal Nuclease Variant truncated Delta+PHS I92E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TR5", "evidence_id": "EV-PDB-1TR5-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1TR5", "doi": "10.1016/j.jmb.2004.05.066", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TR5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature structure of Staphylococcal nuclease variant truncated Delta+PHS I92E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ENB", "evidence_id": "EV-PDB-2ENB-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "2ENB", "doi": "10.1021/bi00192a004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ENB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EXZ", "evidence_id": "EV-PDB-2EXZ-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2EXZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EXZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T22C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EY1", "evidence_id": "EV-PDB-2EY1-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "2EY1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EY1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T22V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EY2", "evidence_id": "EV-PDB-2EY2-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2EY2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EY2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T41C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EY6", "evidence_id": "EV-PDB-2EY6-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "2EY6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EY6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T41V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EYJ", "evidence_id": "EV-PDB-2EYJ-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "2EYJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T62V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EYM", "evidence_id": "EV-PDB-2EYM-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2EYM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T120C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EYP", "evidence_id": "EV-PDB-2EYP-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2EYP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EYP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T120V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0D", "evidence_id": "EV-PDB-2F0D-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "2F0D", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant I92V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0E", "evidence_id": "EV-PDB-2F0E-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "2F0E", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V23L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0G", "evidence_id": "EV-PDB-2F0G-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2F0G", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V66I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0I", "evidence_id": "EV-PDB-2F0I-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2F0I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant I72L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0J", "evidence_id": "EV-PDB-2F0J-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2F0J", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant I72V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0L", "evidence_id": "EV-PDB-2F0L-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2F0L", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V23L/I72L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0M", "evidence_id": "EV-PDB-2F0M-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2F0M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V23L/I72V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0O", "evidence_id": "EV-PDB-2F0O-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2F0O", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V66I/I72V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0P", "evidence_id": "EV-PDB-2F0P-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "2F0P", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V66I/V99I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0S", "evidence_id": "EV-PDB-2F0S-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "2F0S", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V66L/I92V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0T", "evidence_id": "EV-PDB-2F0T-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2F0T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V66L/V99I"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0W", "evidence_id": "EV-PDB-2F0W-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2F0W", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V23I/L25I/V66L/I72L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.9, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F3V", "evidence_id": "EV-PDB-2F3V-1", "mappings": [], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2F3V", "doi": "10.1529/biophysj.106.092155", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F3V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of 1-110 fragment of staphylococcal nuclease with V66W mutation"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "13-mer peptide from Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2FXZ", "evidence_id": "EV-PDB-2FXZ-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2FXZ", "doi": "10.1002/bip.20558", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2FXZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of 97-109 segment of staphylococcal nuclease"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "18-mer peptide from Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2FXY", "evidence_id": "EV-PDB-2FXY-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2FXY", "doi": "10.1002/bip.20558", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2FXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of 55-72 segment of staphylococcal nuclease"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0N", "evidence_id": "EV-PDB-2F0N-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2F0N", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant L25I/I72L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0K", "evidence_id": "EV-PDB-2F0K-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2F0K", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V23I/L25I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0H", "evidence_id": "EV-PDB-2F0H-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "2F0H", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant V66L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F0F", "evidence_id": "EV-PDB-2F0F-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "2F0F", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant L25I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EYO", "evidence_id": "EV-PDB-2EYO-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2EYO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T120S"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EYL", "evidence_id": "EV-PDB-2EYL-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2EYL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EYL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T82S"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EYH", "evidence_id": "EV-PDB-2EYH-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2EYH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T62S"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EYF", "evidence_id": "EV-PDB-2EYF-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2EYF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EYF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T44V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Staphylococcal nuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EY5", "evidence_id": "EV-PDB-2EY5-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2EY5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EY5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease mutant T41S"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1U9R", "evidence_id": "EV-PDB-1U9R-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1U9R", "doi": "10.1529/biophysj.104.048454", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1U9R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Staphylococcal Nuclease mutant V66E/P117G/H124L/S128A at Room Temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DMS", "GOL", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.1, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TT2", "evidence_id": "EV-PDB-1TT2-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1TT2", "doi": "10.1016/j.jmb.2004.05.066", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TT2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic crystal structure of Staphylococcal nuclease variant truncated Delta+PHS I92K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SYG", "evidence_id": "EV-PDB-1SYG-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1SYG", "doi": "10.1021/bi00183a004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SYG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SYF", "evidence_id": "EV-PDB-1SYF-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1SYF", "doi": "10.1021/bi00183a004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SYF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SYE", "evidence_id": "EV-PDB-1SYE-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1SYE", "doi": "10.1021/bi00183a004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SYE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SYC", "evidence_id": "EV-PDB-1SYC-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1SYC", "doi": "10.1021/bi00183a004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SYC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ENGINEERING ALTERNATIVE BETA-TURN TYPES IN STAPHYLOCOCCAL NUCLEASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SYB", "evidence_id": "EV-PDB-1SYB-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1SYB", "doi": "10.1038/339073a0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SYB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "TRANSFER OF A BETA-TURN STRUCTURE TO A NEW PROTEIN CONTEXT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DMS", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "Staphylococcal thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OF1", "evidence_id": "EV-PDB-2OF1-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.92}, "provenance": {"deposit_id": "2OF1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OF1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic crystal structure of the Staphylococcal Nuclease variant truncated Delta+PHS I92W"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2PQE", "evidence_id": "EV-PDB-2PQE-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2PQE", "doi": "10.1021/bi7009794", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2PQE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of proline-free mutant of staphylococcal nuclease"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2QDB", "evidence_id": "EV-PDB-2QDB-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "2QDB", "doi": "10.1016/j.jmb.2008.04.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2QDB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of staphylococcal nuclease variant E75Q/D21N/T33V/T41I/S59A/P117G/S128A at 100 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PO4", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RBM", "evidence_id": "EV-PDB-2RBM-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2RBM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RBM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS I72K at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RDF", "evidence_id": "EV-PDB-2RDF-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.01}, "provenance": {"deposit_id": "2RDF", "doi": "10.1016/j.jmb.2008.04.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RDF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of staphyloccocal nuclease VIAGAN/E75A variant at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2SNM", "evidence_id": "EV-PDB-2SNM-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.97}, "provenance": {"deposit_id": "2SNM", "doi": "10.1016/0022-2836(91)80195-Z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2SNM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "IN A STAPHYLOCOCCAL NUCLEASE MUTANT THE SIDE-CHAIN of A LYSINE REPLACING VALINE 66 IS FULLY BURIED IN THE HYDROPHOBIC CORE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "THERMONUCLEASE PRECURSOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2SNS", "evidence_id": "EV-PDB-2SNS-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "2SNS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2SNS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STAPHYLOCOCCAL NUCLEASE. PROPOSED MECHANISM OF ACTION BASED ON STRUCTURE OF ENZYME-THYMIDINE 3(PRIME),5(PRIME)-BIPHOSPHATE-CALCIUM ION COMPLEX AT 1.5-ANGSTROMS RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "STAPHYLOCOCCAL NUCLEASE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2SOB", "evidence_id": "EV-PDB-2SOB-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2SOB", "doi": "10.1006/jmbi.1995.0365", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2SOB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SN-OB, OB-FOLD SUB-DOMAIN OF STAPHYLOCOCCAL NUCLEASE, NMR, 10 STRUCTURES"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3D4D", "evidence_id": "EV-PDB-3D4D-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3D4D", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3D4D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS Y91E at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3E5S", "evidence_id": "EV-PDB-3E5S-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3E5S", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3E5S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS L103K at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPD", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EJI", "evidence_id": "EV-PDB-3EJI-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3EJI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EJI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS L36K at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ERO", "evidence_id": "EV-PDB-3ERO-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "3ERO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ERO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS I72E at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ERQ", "evidence_id": "EV-PDB-3ERQ-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3ERQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ERQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant L25K at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EVQ", "evidence_id": "EV-PDB-3EVQ-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3EVQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS L25E at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RUZ", "evidence_id": "EV-PDB-3RUZ-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "3RUZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS V74K at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PO4", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OWF", "evidence_id": "EV-PDB-3OWF-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "3OWF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OWF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS V66R at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HZX", "evidence_id": "EV-PDB-3HZX-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3HZX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HZX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Staphylococcal nuclease variant D+PHS/V66K at pH 9 determined at 100 K"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3D6C", "evidence_id": "EV-PDB-3D6C-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3D6C", "doi": "10.1016/j.jmb.2009.03.039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3D6C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MPD", "PO4", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4K6D", "evidence_id": "EV-PDB-4K6D-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "4K6D", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4K6D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant V23M/T62F at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OL7", "evidence_id": "EV-PDB-4OL7-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.67}, "provenance": {"deposit_id": "4OL7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OL7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS V66E A109E at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PMC", "evidence_id": "EV-PDB-4PMC-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "4PMC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PMC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylcoccal nuclease variant Delta+PHS I72K V74K at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PNY", "evidence_id": "EV-PDB-4PNY-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.68}, "provenance": {"deposit_id": "4PNY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PNY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS I72H at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4QB4", "evidence_id": "EV-PDB-4QB4-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "4QB4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4QB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Staphylococcal Nuclease mutant V23L/L25V/V66L"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "THP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XSI", "evidence_id": "EV-PDB-6XSI-1", "mappings": [{"confidence": "high", "justification": "pdTp (ligand THP) bound in the active site.", "rule": "snase-pdtp-bound", "state_id": "SNase-pdTp", "who": "rule:snase-pdtp-bound"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6XSI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XSI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Staphylococcal nuclease variant Delta+PHS V104T at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Disordered protein(D131D) (chains B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K2R", "evidence_id": "EV-PDB-8K2R-2", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8K2R", "doi": "10.1038/s41594-024-01337-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K2R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "The structure of HtpG M domain in complex with unstructured D131D binding site b"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Nuclease A (chains C)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K2T", "evidence_id": "EV-PDB-8K2T-2", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8K2T", "doi": "10.1038/s41594-024-01337-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K2T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of full-length HtpG in complex with D131D"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Thermonuclease (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6EEK", "evidence_id": "EV-PDB-6EEK-1", "mappings": [{"confidence": "low", "justification": "Experimental structure without pdTp; variants (for example the Δ+PHS series) are still native folds.", "rule": "snase-apo-structures", "state_id": "SNase-apo", "who": "rule:snase-apo-structures"}], "molecule_id": "P00644", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6EEK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6EEK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of apo Staphylcoccal nuclease variant Delta+PHS T62E/V66K, pH 7 at cryogenic temperature"}
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{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1SNC-1"], "file": "models/P00644/SNase-pdTp.cif", "format": "mmCIF", "model_id": "SNase-pdTp-cif", "molecule_id": "P00644", "provenance": {"deposit_id": "1SNC", "doi": "10.1002/prot.340050302", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1SNC.cif"}, "record_type": "model", "state_id": "SNase-pdTp"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2PE", "EDO", "FMT", "GOL", "MES", "SO4", "UNX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BARNASE MCOEETI FUSION (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2C4B", "evidence_id": "EV-PDB-2C4B-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "2C4B", "doi": "10.1016/J.JMB.2005.11.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2C4B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Inhibitor cystine knot protein McoEeTI fused to the catalytically inactive barnase mutant H102A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Ribonuclease (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F4Y", "evidence_id": "EV-PDB-2F4Y-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "2F4Y", "doi": "10.1016/j.bbapap.2006.02.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F4Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Barnase cross-linked with glutaraldehyde"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["URE", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Ribonuclease (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F56", "evidence_id": "EV-PDB-2F56-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.955}, "provenance": {"deposit_id": "2F56", "doi": "10.1016/j.bbapap.2006.02.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F56"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Barnase cross-linked with glutaraldehyde soaked in 6M urea"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BRJ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Ribonuclease (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F5M", "evidence_id": "EV-PDB-2F5M-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "2F5M", "doi": "10.1016/j.bbapap.2006.02.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F5M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cross-linked barnase soaked in bromo-ethanol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TOU", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Ribonuclease (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F5W", "evidence_id": "EV-PDB-2F5W-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.001}, "provenance": {"deposit_id": "2F5W", "doi": "10.1016/j.bbapap.2006.02.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F5W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cross-linked barnase soaked in 3 M thiourea"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Ribonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KF3", "evidence_id": "EV-PDB-2KF3-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KF3", "doi": "10.1016/j.bpj.2009.06.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KF3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Barnase, low pressure reference NMR structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Ribonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KF5", "evidence_id": "EV-PDB-2KF5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KF5", "doi": "10.1016/j.bpj.2009.06.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KF5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Barnase bound to d(CGAC), low pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Ribonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KF6", "evidence_id": "EV-PDB-2KF6-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KF6", "doi": "10.1016/j.bpj.2009.06.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KF6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Barnase bound to d(CGAC) high pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Ribonuclease (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZA4", "evidence_id": "EV-PDB-2ZA4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "2ZA4", "doi": "10.1110/ps.073322508", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ZA4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structural Analysis of Barnase-barstar Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Barnase circular permutant (chains A,B,E,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3DA7", "evidence_id": "EV-PDB-3DA7-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "3DA7", "doi": "10.1021/bi900039e", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3DA7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A conformationally strained, circular permutant of barnase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PTD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Ribonuclease (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KCH", "evidence_id": "EV-PDB-3KCH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "3KCH", "doi": "10.1107/S1744309109054037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KCH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Baranase crosslinked by glutaraldehyde"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Ribonuclease (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KF4", "evidence_id": "EV-PDB-2KF4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KF4", "doi": "10.1016/j.bpj.2009.06.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KF4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Barnase high pressure structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BARNASE (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BSB", "evidence_id": "EV-PDB-1BSB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "barnase-structures-native", "state_id": "Barnase-native", "who": "rule:barnase-structures-native"}], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1BSB", "doi": "10.1006/jmbi.1993.1630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BSB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ribonuclease/Ubiquitin chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q3F", "evidence_id": "EV-PDB-3Q3F-1", "mappings": [], "molecule_id": "P00648", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.169}, "provenance": {"deposit_id": "3Q3F", "doi": "10.1016/j.jmb.2011.12.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q3F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin into position 103 of Barnase"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1BGS; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A006F/overview", "evidence_id": "EV-MDDB-A006F", "mappings": [{"confidence": "low", "justification": "Simulation started from a native structure (prediction).", "rule": "barnase-md-native", "state_id": "Barnase-native", "who": "rule:barnase-md-native"}], "molecule_id": "P00648", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A006F", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A006F/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1BGS"}
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{"components": [], "domains": [{"end": 147, "name": "C-type lysozyme", "start": 19}], "gene": "LYZ", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P00698"}, "ligands": ["substrate"], "modifications": [], "molecule_id": "P00698", "molecule_type": "protein", "name": "Lysozyme C", "organism": {"name": "Gallus gallus", "taxon_id": 9031}, "provenance": {"deposit_id": "P00698", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00698/entry"}, "record_type": "molecule", "sequence": "MRSLLILVLCFLPLAALGKVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVQAWIRGCRL", "sequence_length": 147}
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{"assumptions": [], "basis": "observed", "description": "Cross-beta amyloid fibril of hen lysozyme, as in 9J0L (type 1 fibril, cryo-EM, 2.29 Å). Types 1 and 2 (9J0M) and the heat-irreversible fibril (8QV8) are polymorphs and are pooled in this one state.", "family_label": null, "molecule_id": "P00698", "name": "amyloid fibril", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P00698.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P00698.yaml"}, "record_type": "state", "representative_model": "HEWL-fibril-cif", "secondary_structure": null, "state_id": "HEWL-fibril", "status": "draft"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.3, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/193L", "evidence_id": "EV-PDB-193L-1", "mappings": [{"confidence": "high", "justification": "Representative native structure; title and UniProt mapping checked against RCSB.", "rule": "curator_assignment", "state_id": "HEWL-native", "who": "curator:draft (unreviewed)"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.33}, "provenance": {"deposit_id": "193L", "doi": "10.1107/S090744499501674X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/193L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE 1.33 A STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.3, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/194L", "evidence_id": "EV-PDB-194L-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "194L", "doi": "10.1107/S090744499501674X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/194L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE 1.40 A STRUCTURE OF SPACEHAB-01 HEN EGG WHITE LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.48, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AKI", "evidence_id": "EV-PDB-1AKI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1AKI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AKI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE STRUCTURE OF THE ORTHORHOMBIC FORM OF HEN EGG-WHITE LYSOZYME AT 1.5 ANGSTROMS RESOLUTION"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AT6", "evidence_id": "EV-PDB-1AT6-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1AT6", "doi": "10.1006/jmbi.1998.1674", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AT6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEN EGG WHITE LYSOZYME WITH A ISOASPARTATE RESIDUE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BGI", "evidence_id": "EV-PDB-1BGI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1BGI", "doi": "10.1107/S0907444998008713", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BGI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ORTHORHOMBIC LYSOZYME CRYSTALLIZED AT HIGH TEMPERATURE (310K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "LYSOZYME (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BVK", "evidence_id": "EV-PDB-1BVK-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1BVK", "doi": "10.1084/jem.187.4.479", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BVK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PROTEIN (LYSOZYME) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BWH", "evidence_id": "EV-PDB-1BWH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1BWH", "doi": "10.1107/S0907444998016047", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE 1.8 A STRUCTURE OF GROUND CONTROL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PROTEIN (LYSOZYME) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BWI", "evidence_id": "EV-PDB-1BWI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1BWI", "doi": "10.1107/S0907444998016047", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BWI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE 1.8 A STRUCTURE OF MICROBATCH OIL DROP GROWN TETRAGONAL HEN EGG WHITE LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PROTEIN (LYSOZYME) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BWJ", "evidence_id": "EV-PDB-1BWJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1BWJ", "doi": "10.1107/S0907444998016047", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE 1.8 A STRUCTURE OF MICROGRAVITY GROWN TETRAGONAL HEN EGG WHITE LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HEM", "evidence_id": "EV-PDB-1HEM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1HEM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HEM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -149.15}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BHZ", "evidence_id": "EV-PDB-1BHZ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "1BHZ", "doi": "10.1107/S090744499800626X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF HEN EGG WHITE LYSOZYME FROM MASC DATA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "LYSOZYME (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HF4", "evidence_id": "EV-PDB-1HF4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "1HF4", "doi": "10.1107/S0907444901004504", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HF4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "LYSOZYME C (chains Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IC4", "evidence_id": "EV-PDB-1IC4-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1IC4", "doi": "10.1074/jbc.M100480200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "LYSOZYME C (chains Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IC7", "evidence_id": "EV-PDB-1IC7-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1IC7", "doi": "10.1074/jbc.M100480200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IC7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IEE", "evidence_id": "EV-PDB-1IEE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.94}, "provenance": {"deposit_id": "1IEE", "doi": "10.1107/S0907444901008873", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IEE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME AT 0.94 A FROM CRYSTALS GROWN BY THE COUNTER-DIFFUSION METHOD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IO5", "evidence_id": "EV-PDB-1IO5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1IO5", "doi": "10.1038/nsb1197-909", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IO5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "neutron", "title": "HYDROGEN AND HYDRATION OF HEN EGG-WHITE LYSOZYME DETERMINED BY NEUTRON DIFFRACTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IOR", "evidence_id": "EV-PDB-1IOR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.76}, "provenance": {"deposit_id": "1IOR", "doi": "10.1110/ps.37401", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IOR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IOS", "evidence_id": "EV-PDB-1IOS-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.76}, "provenance": {"deposit_id": "1IOS", "doi": "10.1110/ps.37401", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IOS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IOT", "evidence_id": "EV-PDB-1IOT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "1IOT", "doi": "10.1110/ps.37401", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IOT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IR7", "evidence_id": "EV-PDB-1IR7-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1IR7", "doi": "10.1093/protein/14.6.421", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IR7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "IM mutant of lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IR9", "evidence_id": "EV-PDB-1IR9-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1IR9", "doi": "10.1093/protein/14.6.421", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IR9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "IM mutant of lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LJ4", "evidence_id": "EV-PDB-1LJ4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "1LJ4", "doi": "10.1107/S0907444902007126", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LJ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KXX", "evidence_id": "EV-PDB-1KXX-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.71}, "provenance": {"deposit_id": "1KXX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KXX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KXW", "evidence_id": "EV-PDB-1KXW-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "1KXW", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KXW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JPO", "evidence_id": "EV-PDB-1JPO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1JPO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JPO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LOW TEMPERATURE ORTHORHOMBIC LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IOQ", "evidence_id": "EV-PDB-1IOQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.79}, "provenance": {"deposit_id": "1IOQ", "doi": "10.1110/ps.37401", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IOQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.6, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HSW", "evidence_id": "EV-PDB-1HSW-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1HSW", "doi": "10.1107/S0907444998015522", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HSW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LYSOZYME (MUCOPEPTIDE N-ACETYLMURAMYL HYDROLASE)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LZC", "evidence_id": "EV-PDB-1LZC-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1LZC", "doi": "10.1006/jmbi.1994.0139", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LZC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LZD", "evidence_id": "EV-PDB-1LZD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1LZD", "doi": "10.1006/jmbi.1994.0139", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LZD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LZG", "evidence_id": "EV-PDB-1LZG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1LZG", "doi": "10.1006/jmbi.1994.0139", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LZG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LZH", "evidence_id": "EV-PDB-1LZH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.0}, "provenance": {"deposit_id": "1LZH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LZH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE STRUCTURES OF THE MONOCLINIC AND ORTHORHOMBIC FORMS OF HEN EGG-WHITE LYSOZYME AT 6 ANGSTROMS RESOLUTION."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LZT", "evidence_id": "EV-PDB-1LZT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.97}, "provenance": {"deposit_id": "1LZT", "doi": "10.1107/S0108768189009183", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LZT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "REFINEMENT OF TRICLINIC LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MLC", "evidence_id": "EV-PDB-1MLC-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1MLC", "doi": "10.1016/0022-2836(94)90046-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MLC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NBY", "evidence_id": "EV-PDB-1NBY-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1NBY", "doi": "10.1021/bi020589+", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HyHEL-63 complexed with HEL mutant K96A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RJC", "evidence_id": "EV-PDB-1RJC-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1RJC", "doi": "10.1074/jbc.M413011200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RJC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LZA", "evidence_id": "EV-PDB-1LZA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1LZA", "doi": "10.1006/jmbi.1994.0139", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LZA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Hen Egg White Lysozyme (chains Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YQV", "evidence_id": "EV-PDB-1YQV-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1YQV", "doi": "10.1107/S0907444905007870", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of the antibody Fab HyHEL5 complex with lysozyme at 1.7A resolution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains L,M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZMY", "evidence_id": "EV-PDB-1ZMY-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "1ZMY", "doi": "10.1016/j.jmb.2005.07.038", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1XGT", "evidence_id": "EV-PDB-1XGT-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1XGT", "doi": "10.1016/j.str.2004.12.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1XGT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure for antibody HyHEL-63 Y33L mutant complexed with hen egg lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2BLY", "evidence_id": "EV-PDB-2BLY-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "2BLY", "doi": "10.1107/S0907444905019360", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2BLY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL after a high dose x-ray \"burn\""}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2C8P", "evidence_id": "EV-PDB-2C8P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "2C8P", "doi": "10.1107/S0907444905041429", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2C8P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "lysozyme (60sec) and UV laser excited fluorescence"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NO2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2YBN", "evidence_id": "EV-PDB-2YBN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2YBN", "doi": "10.1107/S0909049511007163", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2YBN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nitrate X-ray induced reduction on HEWL crystals (28.6 MGy)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Lysozyme C (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2YSS", "evidence_id": "EV-PDB-2YSS-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "2YSS", "doi": "10.1110/ps.073156708", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2YSS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Humanized HYHEL-10 FV mutant(HQ39KW47Y)-HEN lysozyme complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains Y,Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZNW", "evidence_id": "EV-PDB-2ZNW-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "2ZNW", "doi": "10.1021/bi300455t", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ZNW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of ScFv10 in Complex with Hen Egg Lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains Y,Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZNX", "evidence_id": "EV-PDB-2ZNX-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "2ZNX", "doi": "10.1021/bi300455t", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ZNX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EXD", "evidence_id": "EV-PDB-3EXD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.49}, "provenance": {"deposit_id": "3EXD", "doi": "10.1107/S0909049508034870", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Sulfur-SAD phased HEWL Crystal"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HFM", "evidence_id": "EV-PDB-3HFM-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "3HFM", "doi": "10.1073/pnas.86.15.5938", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HFM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF AN ANTIBODY-ANTIGEN COMPLEX. CRYSTAL STRUCTURE OF THE HY/HEL-10 FAB-LYSOZYME COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IJU", "evidence_id": "EV-PDB-3IJU-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3IJU", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IJU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Chicken egg white lysozyme by highly ordered APA (Anodic Porous Alumina) nanotemplate crystallization method"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "CMO", "NA", "RE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KAM", "evidence_id": "EV-PDB-3KAM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.59}, "provenance": {"deposit_id": "3KAM", "doi": "10.1039/b923688k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KAM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg White Lysozyme Derivatized with rhenium(I) diaquatricarbonyl cation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LYM", "evidence_id": "EV-PDB-3LYM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3LYM", "doi": "10.1016/0022-2836(87)90634-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME AT A HYDROSTATIC PRESSURE OF 1000 ATMOSPHERES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CCN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.3, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LYO", "evidence_id": "EV-PDB-3LYO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.93}, "provenance": {"deposit_id": "3LYO", "doi": "10.1016/S0167-4838(98)00027-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 95% ACETONITRILE-WATER"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TMX", "evidence_id": "EV-PDB-3TMX-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3TMX", "doi": "10.1107/S0907444911032835", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TMX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Dose=1.9MGy)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TXD", "evidence_id": "EV-PDB-3TXD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "3TXD", "doi": "10.1107/S0021889812044172", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallization with carboplatin in aqueous media with glycerol as the cryoprotectant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "CPT", "DMS", "GOL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TXF", "evidence_id": "EV-PDB-3TXF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "3TXF", "doi": "10.1107/S0021889812044172", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TXF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallization with cisplatin in DMSO media with glycerol as the cryoprotectant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "DMS", "NA", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TXI", "evidence_id": "EV-PDB-3TXI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3TXI", "doi": "10.1107/S0021889812044172", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TXI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallization with carboplatin in DMSO media with paratone as the cryoprotectant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ULR", "evidence_id": "EV-PDB-3ULR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "3ULR", "doi": "10.1107/S1744309111056132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ULR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lysozyme contamination facilitates crystallization of a hetero-trimericCortactin:Arg:Lysozyme complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WMK", "evidence_id": "EV-PDB-3WMK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.46}, "provenance": {"deposit_id": "3WMK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WMK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Hen egg-white lysozyme in pH 4.5 Sodium Acetatewith 1M NaCl at 277K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WPJ", "evidence_id": "EV-PDB-3WPJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3WPJ", "doi": "10.1038/srep05731", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WPJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPATIOTEMPORAL DEVELOPMENT of SOAKED PROTEIN CRYSTAL; NATIVE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PT4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WPK", "evidence_id": "EV-PDB-3WPK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3WPK", "doi": "10.1038/srep05731", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WPK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPATIOTEMPORAL DEVELOPMENT of SOAKED PROTEIN CRYSTAL; 750 SEC"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PT4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WU7", "evidence_id": "EV-PDB-3WU7-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3WU7", "doi": "10.1038/srep05731", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WU7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Spatiotemporal development of soaked protein crystal; derivative 250 sec"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "DMS", "GOL", "NA", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TXH", "evidence_id": "EV-PDB-3TXH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "3TXH", "doi": "10.1107/S0021889812044172", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TXH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallization with carboplatin in DMSO media with glycerol as the cryoprotectant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "CPT", "DMS", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TXG", "evidence_id": "EV-PDB-3TXG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3TXG", "doi": "10.1107/S0021889812044172", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TXG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MEB", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TXE", "evidence_id": "EV-PDB-3TXE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3TXE", "doi": "10.1107/S0021889812044172", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TXE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallization with carboplatin in aqueous media with paratone as the cryoprotectant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "REI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.54, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3QE8", "evidence_id": "EV-PDB-3QE8-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.49}, "provenance": {"deposit_id": "3QE8", "doi": "10.1021/ic2023314", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3QE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure Analysis of Lysozyme-bound fac-[Re(CO)3(H2O)(Im)]+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LYSOZYME C (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A8A", "evidence_id": "EV-PDB-4A8A-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 14.2}, "provenance": {"deposit_id": "4A8A", "doi": "10.1038/NSMB.2210", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A8A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LYSOZYME C (chains M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4A8B", "evidence_id": "EV-PDB-4A8B-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 13.0}, "provenance": {"deposit_id": "4A8B", "doi": "10.1038/NSMB.2210", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4A8B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CHT", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -210.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AGA", "evidence_id": "EV-PDB-4AGA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4AGA", "doi": "10.1039/C2CE25129A", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AGA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hofmeister effects of ionic liquids in protein crystallization: direct and water-mediated interactions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AXT", "evidence_id": "EV-PDB-4AXT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "4AXT", "doi": "10.1107/S0907444912031459", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AXT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM AN AUTO HARVESTED CRYSTAL, Control Experiment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4B0D", "evidence_id": "EV-PDB-4B0D-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "4B0D", "doi": "10.1107/S0907444912031459", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4B0D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM AN AUTO HARVESTED CRYSTAL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "K3G", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -113.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4B1A", "evidence_id": "EV-PDB-4B1A-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.67}, "provenance": {"deposit_id": "4B1A", "doi": "10.1039/C2DT32174B", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4B1A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of lysozyme with Keggin molecule"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MRD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4B4E", "evidence_id": "EV-PDB-4B4E-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.0}, "provenance": {"deposit_id": "4B4E", "doi": "10.1107/S1399004714025061", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4B4E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "EU3", "HM6", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BAD", "evidence_id": "EV-PDB-4BAD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "4BAD", "doi": "10.1039/C2CC36982F", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BAD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen egg-white lysozyme structure in complex with the europium tris- hydroxymethyltriazoledipicolinate complex at 1.35 A resolution."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "EU3", "IKX", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BAF", "evidence_id": "EV-PDB-4BAF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.507}, "provenance": {"deposit_id": "4BAF", "doi": "10.1039/C2CC36982F", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BAF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["YB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "LYSOZYME C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BS7", "evidence_id": "EV-PDB-4BS7-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.701}, "provenance": {"deposit_id": "4BS7", "doi": "10.1021/CG301757G", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BS7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen egg-white lysozyme structure determined at room temperature by in- situ diffraction and SAD phasing in ChipX"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I8S", "evidence_id": "EV-PDB-4I8S-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4I8S", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I8S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Lysozyme protein crystallization via standard hanging drop vapor diffusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IAT", "evidence_id": "EV-PDB-4IAT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4IAT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IAT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEW Lysozyme by langmuir- blodgett modified vapour diffusion"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "RU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4J1B", "evidence_id": "EV-PDB-4J1B-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.66}, "provenance": {"deposit_id": "4J1B", "doi": "10.1021/ic4004142", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4J1B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct between hen egg white lysozyme and AziRu (black crystal)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "RBN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4J7V", "evidence_id": "EV-PDB-4J7V-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.54}, "provenance": {"deposit_id": "4J7V", "doi": "10.1002/asia.201301347", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4J7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of cross-linked hen egg white lysozyme soaked with 5mM [Ru(benzene)Cl2]2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "LCP", "NI", "SNF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KXI", "evidence_id": "EV-PDB-4KXI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4KXI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KXI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystallographic study of the complex of Ni(II) Schiff base complex and HEW Lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AU", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LFX", "evidence_id": "EV-PDB-4LFX-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "4LFX", "doi": "10.1039/c3cc46400h", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LFX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AU", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LGK", "evidence_id": "EV-PDB-4LGK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "4LGK", "doi": "10.1039/c3cc46400h", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LGK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct between hen egg white lysozyme and Au2Phen, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "MPD", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LT1", "evidence_id": "EV-PDB-4LT1-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "4LT1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LT1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallised with Carboplatin in non-NaCl conditions: crystal 1 processed using the XDS software package"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "MPD", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -146.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LT2", "evidence_id": "EV-PDB-4LT2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4LT2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LT2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL co-crystallized with Carboplatin in non-NaCl conditions: crystal 2 processed using the EVAL software package"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LYB", "evidence_id": "EV-PDB-4LYB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.21}, "provenance": {"deposit_id": "4LYB", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LYB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CdS within a lysoyzme single crystal"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LYC", "evidence_id": "EV-PDB-4LYC-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "4LYC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LYC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cd ions within a lysoyzme single crystal"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.3, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LYO", "evidence_id": "EV-PDB-4LYO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "4LYO", "doi": "10.1016/S0167-4838(98)00027-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN NEAT ACETONITRILE, THEN BACK-SOAKED IN WATER"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LZT", "evidence_id": "EV-PDB-4LZT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.95}, "provenance": {"deposit_id": "4LZT", "doi": "10.1107/S0907444997013656", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LZT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ATOMIC RESOLUTION REFINEMENT OF TRICLINIC HEW LYSOZYME AT 295K"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LYT", "evidence_id": "EV-PDB-4LYT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "4LYT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LYT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LYM", "evidence_id": "EV-PDB-4LYM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "4LYM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF LOW HUMIDITY TETRAGONAL LYSOZYME AT 2.1-ANGSTROMS RESOLUTION. VARIABILITY IN HYDRATION SHELL AND ITS STRUCTURAL CONSEQUENCES"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AU", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LFP", "evidence_id": "EV-PDB-4LFP-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "4LFP", "doi": "10.1039/c3cc46400h", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LFP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct between hen egg white lysozyme and a homoleptic gold(I) complex with the saccharynate ligand"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IAS", "evidence_id": "EV-PDB-4IAS-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "4IAS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IAS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEW Lysozyme by langmuir- blodgett modified vapour diffusion"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "CS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NG8", "evidence_id": "EV-PDB-4NG8-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.09}, "provenance": {"deposit_id": "4NG8", "doi": "10.1107/S1399004714011304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NG8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Dialyzed HEW lysozyme batch crystallized in 1.9 M CsCl and collected at 100 K."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "RB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NGJ", "evidence_id": "EV-PDB-4NGJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "4NGJ", "doi": "10.1107/S1399004714011304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NGJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Dialyzed HEW lysozyme batch crystallized in 1.0 M RbCl and collected at 100 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "CO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NGK", "evidence_id": "EV-PDB-4NGK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4NGK", "doi": "10.1107/S1399004714011304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NGK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Previously de-ionized HEW lysozyme batch crystallized in 0.2 M CoCl2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "YB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NGV", "evidence_id": "EV-PDB-4NGV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.64}, "provenance": {"deposit_id": "4NGV", "doi": "10.1107/S1399004714011304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NGV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Previously de-ionized HEW lysozyme batch crystallized in 0.5 M YbCl3"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "YB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NGY", "evidence_id": "EV-PDB-4NGY-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "4NGY", "doi": "10.1107/S1399004714011304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NGY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Dialyzed HEW lysozyme batch crystallized in 0.75 M YbCl3 and collected at 100 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "YB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -148.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NGZ", "evidence_id": "EV-PDB-4NGZ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4NGZ", "doi": "10.1107/S1399004714011304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NGZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Previously de-ionized HEW lysozyme crystallized in 0.5 M YbCl3/30% (v/v) glycerol and collected at 125K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NHI", "evidence_id": "EV-PDB-4NHI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.34}, "provenance": {"deposit_id": "4NHI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NHI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Hen egg-white lysozyme in Tris buffer at pH 7.5 with Magnesium formate"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2T8", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NHQ", "evidence_id": "EV-PDB-4NHQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.92}, "provenance": {"deposit_id": "4NHQ", "doi": "10.1021/ic501498g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NHQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (5 days)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2T8", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NHS", "evidence_id": "EV-PDB-4NHS-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "4NHS", "doi": "10.1021/ic501498g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (9 days)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AU", "EDO", "NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OOT", "evidence_id": "EV-PDB-4OOT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "4OOT", "doi": "10.1021/ml500231b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OOT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the protein-gold adduct formed upon reaction of Aubipic with hen egg white lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AU", "EDO", "NA", "NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4QY9", "evidence_id": "EV-PDB-4QY9-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "4QY9", "doi": "10.1039/c4dt02332c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4QY9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct between hen egg white lysozyme and Auoxo3, a cytotoxic gold(III) compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["I83"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4QGZ", "evidence_id": "EV-PDB-4QGZ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "4QGZ", "doi": "10.1021/ic5012583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4QGZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct formed between hen egg white lysozyme and trans-dimethylamine methylamine dichlorido platinum(II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4QEQ", "evidence_id": "EV-PDB-4QEQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.381}, "provenance": {"deposit_id": "4QEQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4QEQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High resolution structure of egg white lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "T3Y"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PRU", "evidence_id": "EV-PDB-4PRU-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "4PRU", "doi": "10.1039/C4SC02383H", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PRU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of dimethyllysine hen egg-white lysozyme in complex with sclx4 at 2.2 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "P6G", "PG4", "PG6", "T3Y"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PRQ", "evidence_id": "EV-PDB-4PRQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "4PRQ", "doi": "10.1039/c4cc04897k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PRQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH SCLX4 AT 1.72 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PT", "EDO", "NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PPO", "evidence_id": "EV-PDB-4PPO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.73}, "provenance": {"deposit_id": "4PPO", "doi": "10.1039/c4cc02254h", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PPO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "First Crystal Structure for an Oxaliplatin-Protein Complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PGJ", "evidence_id": "EV-PDB-4PGJ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "4PGJ", "doi": "10.1074/jbc.M114.614842", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PGJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human heavy-chain domain antibody in complex with hen egg-white lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "NA", "PT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OWE", "evidence_id": "EV-PDB-4OWE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.41}, "provenance": {"deposit_id": "4OWE", "doi": "10.1107/S2053230X14014009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OWE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PtCl6 binding to HEWL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "IOD", "NA", "PT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OWC", "evidence_id": "EV-PDB-4OWC-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.62}, "provenance": {"deposit_id": "4OWC", "doi": "10.1107/S2053230X14014009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OWC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PtI6 binding to HEWL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BR", "CL", "DMS", "MEB", "NA", "PT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OWB", "evidence_id": "EV-PDB-4OWB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "4OWB", "doi": "10.1107/S2053230X14013995", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OWB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cisplatin binding to HEWL under sodium bromide crystallisation conditions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "DMS", "IOD", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OWA", "evidence_id": "EV-PDB-4OWA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.796}, "provenance": {"deposit_id": "4OWA", "doi": "10.1107/S2053230X14013995", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OWA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Carboplatin binding to HEWL under sodium iodide crystallisation conditions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "RU0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OOO", "evidence_id": "EV-PDB-4OOO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "4OOO", "doi": "10.1002/anie.201403337", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OOO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the lysozyme derivative of tetrakis(acetato)chlorido diruthenium(II,III) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4O34", "evidence_id": "EV-PDB-4O34-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.09}, "provenance": {"deposit_id": "4O34", "doi": "10.1107/S2052252514010070", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4O34"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature macromolecular serial crystallography using synchrotron radiation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "RU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NY5", "evidence_id": "EV-PDB-4NY5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "4NY5", "doi": "10.1039/c3dt53582g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NY5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct formed between hen egg white lysozyme and NAMI-A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "XE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NWH", "evidence_id": "EV-PDB-4NWH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "4NWH", "doi": "10.1097/ALN.0000000000000435", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lysozyme UNDER 30 BAR PRESSURE OF XENON"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "N2O"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NWE", "evidence_id": "EV-PDB-4NWE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "4NWE", "doi": "10.1097/ALN.0000000000000435", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NWE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lysozyme UNDER 30 BAR PRESSURE OF NITROUS OXIDE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "FMT", "NA", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NSJ", "evidence_id": "EV-PDB-4NSJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4NSJ", "doi": "10.1107/S2053230X14016161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NSJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Carboplatin binding to HEWL in 2M NH4formate, 0.1M HEPES at pH 7.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "FLC", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NSI", "evidence_id": "EV-PDB-4NSI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "4NSI", "doi": "10.1107/S2053230X14016161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NSI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Carboplatin binding to HEWL in 20% propanol, 20% PEG 4000 at pH5.6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "DMS", "QPT", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NSH", "evidence_id": "EV-PDB-4NSH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "4NSH", "doi": "10.1107/S2053230X14016161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NSH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Carboplatin binding to HEWL in 0.2M NH4SO4, 0.1M NaAc in 25% PEG 4000 at pH 4.6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BR", "DMS", "NA", "QPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NSG", "evidence_id": "EV-PDB-4NSG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4NSG", "doi": "10.1107/S2053230X14016161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NSG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Carboplatin binding to HEWL in NaBr crystallisation conditions studied at an X-ray wavelength of 1.5418A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XJD", "evidence_id": "EV-PDB-4XJD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.801}, "provenance": {"deposit_id": "4XJD", "doi": "10.1107/S1399004715005210", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XJD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of Lysozyme2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LYT", "evidence_id": "EV-PDB-5LYT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "5LYT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LYT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OOV", "evidence_id": "EV-PDB-5OOV-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.365}, "provenance": {"deposit_id": "5OOV", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Designed Ankyrin Repeat Protein (DARPin) ETVD-1 in complex with Lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains B,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OOY", "evidence_id": "EV-PDB-5OOY-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "5OOY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OOY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Designed Ankyrin Repeat Protein (DARPin) VHAH-1 in complex with Lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GAI", "GOL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A4Q", "evidence_id": "EV-PDB-6A4Q-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "6A4Q", "doi": "10.1016/j.ijbiomac.2018.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A4Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL crystals soaked in 2.5M GuHCl for 110 minutes"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GAI", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A4P", "evidence_id": "EV-PDB-6A4P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.76}, "provenance": {"deposit_id": "6A4P", "doi": "10.1016/j.ijbiomac.2018.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A4P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL crystals soaked in 2.5M GuHCl for 40 minutes"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GAI", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A4O", "evidence_id": "EV-PDB-6A4O-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "6A4O", "doi": "10.1016/j.ijbiomac.2018.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A4O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HEWL crystals soaked in 2.5M GuHCl for 20 minutes"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A10", "evidence_id": "EV-PDB-6A10-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.13}, "provenance": {"deposit_id": "6A10", "doi": "10.1021/acs.cgd.9b00256", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A10"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hen egg white lysozyme crystallized by ammonium sulfate"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme C (chains A,B)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5O4W", "evidence_id": "EV-PDB-5O4W-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.11}, "provenance": {"deposit_id": "5O4W", "doi": "10.1107/S2059798317010348", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5O4W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "Protein structure determination by electron diffraction using a single three-dimensional nanocrystal"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NJR", "evidence_id": "EV-PDB-5NJR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "5NJR", "doi": "10.1107/S2052252517013124", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NJR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 50s time-delay, phased with 4ET8"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NJM", "evidence_id": "EV-PDB-5NJM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "5NJM", "doi": "10.1038/s41467-017-00630-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NJM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lysozyme room-temperature structure determined by serial millisecond crystallography"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NE0", "evidence_id": "EV-PDB-5NE0-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.57}, "provenance": {"deposit_id": "5NE0", "doi": "10.1107/S1600576717005799", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NE0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature in-situ structure of hen egg-white lysozyme from crystals enclosed between ultrathin silicon nitride membranes"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "RE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NBJ", "evidence_id": "EV-PDB-5NBJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.266}, "provenance": {"deposit_id": "5NBJ", "doi": "10.1107/S2052252517003475", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NBJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DLS Tetragonal - ReHEWL"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HEN EGG WHITE LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LYZ", "evidence_id": "EV-PDB-5LYZ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "5LYZ", "doi": "10.1016/0022-2836(74)90598-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LYZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Real-space refinement of the structure of hen egg-white lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "GOL", "NA", "RU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LVJ", "evidence_id": "EV-PDB-5LVJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "5LVJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LVJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg White Lysozyme co-crystallized with [H2Ind][trans-RuCl4(DMSO)(HInd)]"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "NA", "RU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LVI", "evidence_id": "EV-PDB-5LVI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "5LVI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LVI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg White Lysozyme co-crystallized with [HIsq][trans-RuCl4(DMSO)(Isq)]"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "GOL", "NA", "RU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LVH", "evidence_id": "EV-PDB-5LVH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "5LVH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LVH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg White Lysozyme co-crystallized with trans-Ru(DMSO)4Cl2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "NA", "RU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LVG", "evidence_id": "EV-PDB-5LVG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "5LVG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LVG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg White Lysozyme co-crystallized with cis-Ru(DMSO)4Cl2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LIO", "evidence_id": "EV-PDB-5LIO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.496}, "provenance": {"deposit_id": "5LIO", "doi": "10.1107/S2059798316012304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LIO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lysozyme, collected at rotation 360 degree per second"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["9U3", "CL", "EDO", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6AD5", "evidence_id": "EV-PDB-6AD5-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.", "rule": "hewl-fibril-structures", "state_id": "HEWL-fibril", "who": "rule:hewl-fibril-structures"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "6AD5", "doi": "10.1371/journal.pone.0232953", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6AD5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HEWL in complex with TEMED (in the aroma form) after 24 hours under fibrillation conditions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["9U3", "ACT", "CL", "NA", "PGO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ADF", "evidence_id": "EV-PDB-6ADF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.08}, "provenance": {"deposit_id": "6ADF", "doi": "10.1371/journal.pone.0232953", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ADF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of HEWL co-crystallised with TEMED"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["9U3", "CL", "NA", "PGO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6AEA", "evidence_id": "EV-PDB-6AEA-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.", "rule": "hewl-fibril-structures", "state_id": "HEWL-fibril", "who": "rule:hewl-fibril-structures"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "6AEA", "doi": "10.1371/journal.pone.0232953", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6AEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HEWL in complex with TEMED (in the aroma form) after 5 hours under fibrillation conditions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "EDO", "NA", "PEL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6AGR", "evidence_id": "EV-PDB-6AGR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.22}, "provenance": {"deposit_id": "6AGR", "doi": "10.1016/j.ijbiomac.2019.12.204", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6AGR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of HEWL co-crystallised with phenylethyl alcohol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "PEL", "PGO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6AHH", "evidence_id": "EV-PDB-6AHH-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.", "rule": "hewl-fibril-structures", "state_id": "HEWL-fibril", "who": "rule:hewl-fibril-structures"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "6AHH", "doi": "10.1038/s41598-019-55082-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6AHH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HEWL in complex with Phenylethyl alcohol (in the aroma form) after 5 hours under fibrillation conditions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CIN", "CL", "NA", "PGO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6AHL", "evidence_id": "EV-PDB-6AHL-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as an amyloid fibril; a fibril entry shows the cross-beta fibril fold, not the native fold. Polymorphs are pooled.", "rule": "hewl-fibril-structures", "state_id": "HEWL-fibril", "who": "rule:hewl-fibril-structures"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "6AHL", "doi": "10.1038/s41598-019-55082-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6AHL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HEWL in complex with Cinnamaldehyde (in the aroma form) after 5 hours under fibrillation conditions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "GOL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6B7U", "evidence_id": "EV-PDB-6B7U-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.581}, "provenance": {"deposit_id": "6B7U", "doi": "10.1016/j.ifset.2018.02.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6B7U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of hen egg-white lysozyme without high-pressure pre-treatment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "GOL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6B7V", "evidence_id": "EV-PDB-6B7V-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.482}, "provenance": {"deposit_id": "6B7V", "doi": "10.1016/j.ifset.2018.02.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6B7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of hen egg-white lysozyme pre-treated with high-pressure homogenization at 120 MPa"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["E3D", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BO1", "evidence_id": "EV-PDB-6BO1-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.24}, "provenance": {"deposit_id": "6BO1", "doi": "10.1039/c8cc02433b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BO1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mono-adduct formed after 3 days in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "E3D", "NA", "RU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BO2", "evidence_id": "EV-PDB-6BO2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "6BO2", "doi": "10.1039/c8cc02433b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BO2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Adducts formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD", "CL", "EDO", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BRE", "evidence_id": "EV-PDB-6BRE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "6BRE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BRE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg-White Lysozyme cocrystallized with Cadmium sulphate using CuKalpha source."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F44"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6CIW", "evidence_id": "EV-PDB-6CIW-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.42}, "provenance": {"deposit_id": "6CIW", "doi": "10.1039/C8PY00545A", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6CIW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg White Lysozyme Cocrystallized with 1,3-Di(2-pyridyl)propane"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6D6E", "evidence_id": "EV-PDB-6D6E-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6D6E", "doi": "10.1107/S2059798318008793", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6D6E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Triclinic lysozyme (295 K) in the presence of 47% xylose"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "PGO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ABZ", "evidence_id": "EV-PDB-6ABZ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "6ABZ", "doi": "10.1016/j.ijbiomac.2019.12.204", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ABZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HEWL in deionized water"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6HT2", "evidence_id": "EV-PDB-6HT2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "6HT2", "doi": "10.1107/S2052252518017657", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6HT2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF HEWL BY ELECTRON DIFFRACTION AND MICROFOCUS DIFFRACTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "CWO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6HY4", "evidence_id": "EV-PDB-6HY4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "6HY4", "doi": "10.1002/ejic.201801113", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6HY4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Co(II)-substituted Wells-Dawson binding to Hen Egg-White Lysozyme (HEWL)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QQE", "evidence_id": "EV-PDB-6QQE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.37}, "provenance": {"deposit_id": "6QQE", "doi": "10.1107/S205225251900616X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QQE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 20 kGy"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "DO3", "GD", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SR4", "evidence_id": "EV-PDB-6SR4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "6SR4", "doi": "10.1038/s41467-020-15610-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SR4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray pump X-ray probe on lysozyme.Gd nanocrystals: 112 fs time delay"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CW8", "evidence_id": "EV-PDB-8CW8-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.57}, "provenance": {"deposit_id": "8CW8", "doi": "10.1038/s41557-023-01329-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CW8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Laser Off Temperature-Jump XFEL structure of Lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IOM", "ACT", "CL", "NA", "VVB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains AAA)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9GOG", "evidence_id": "EV-PDB-9GOG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.24}, "provenance": {"deposit_id": "9GOG", "doi": "10.1016/j.jinorgbio.2024.112787", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9GOG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of lysozyme obtained upon reaction with the dioxidovanadium(V) complex with furan-2-carboxylic acid (3-ethoxy-2-hydroxybenzylidene)hydrazide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ION", "ACT", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains AAA)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9GOK", "evidence_id": "EV-PDB-9GOK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.18}, "provenance": {"deposit_id": "9GOK", "doi": "10.1016/j.jinorgbio.2024.112787", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9GOK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of lysozyme obtained upon reaction with the dioxidovanadium(V) complex with (E)-N'-(1-(2-hydroxy-5-methoxyphenyl)ethylidene)furan-2-carbohydrazide)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9H3E", "evidence_id": "EV-PDB-9H3E-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "9H3E", "doi": "10.1002/2211-5463.13932", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9H3E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen egg white lysozyme crystallization and structure determination at room temperature in the CrystalChip"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ISW", "CL", "EDO", "IMD", "NA", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9H7W", "evidence_id": "EV-PDB-9H7W-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.13}, "provenance": {"deposit_id": "9H7W", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9H7W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen Egg White Lysozyme in Complex with Imidizole"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "GTQ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HC2", "evidence_id": "EV-PDB-9HC2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.27}, "provenance": {"deposit_id": "9HC2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HC2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Lysozyme in complex with Gentisic Acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "IOD", "NH3", "PT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains AAA)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HLK", "evidence_id": "EV-PDB-9HLK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "9HLK", "doi": "10.1021/acs.inorgchem.4c05424", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HLK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the adduct formed upon reaction of the diiodido analogue of picoplatin with lysozyme (structure A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IOD", "NH3", "PT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains AAA)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HMQ", "evidence_id": "EV-PDB-9HMQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "9HMQ", "doi": "10.1021/acs.inorgchem.4c05424", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HMQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-structure of the adduct formed upon reaction of the diiodido analogue of picoplatin with lysozyme (structure C)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IXG", "MES", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HRU", "evidence_id": "EV-PDB-9HRU-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.88}, "provenance": {"deposit_id": "9HRU", "doi": "10.1021/jacs.5c08121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HRU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The Lysozyme - pctx complex in space group P3121"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IXJ", "ACT", "CL", "DMS", "EDO", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HTI", "evidence_id": "EV-PDB-9HTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.17}, "provenance": {"deposit_id": "9HTI", "doi": "10.1039/d5sc05555e", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Adduct formed during the incubation of dichloro(3-benzylbenzoselenazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IXK", "ACT", "CL", "DMS", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HTJ", "evidence_id": "EV-PDB-9HTJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.49}, "provenance": {"deposit_id": "9HTJ", "doi": "10.1039/d5sc05555e", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Adduct formed during the incubation of dichloro(3-benzylbenzothiazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9I6K", "evidence_id": "EV-PDB-9I6K-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "9I6K", "doi": "10.1038/s41598-025-25449-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9I6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen egg-white lysozyme structure at 85% relative humidity"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9I6N", "evidence_id": "EV-PDB-9I6N-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "9I6N", "doi": "10.1038/s41598-025-25449-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9I6N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen egg-white lysozyme structure collected at EuXFEL SPB/SFX with HVE injection method"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9I6P", "evidence_id": "EV-PDB-9I6P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "9I6P", "doi": "10.1038/s41598-025-25449-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9I6P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hen egg-white lysozyme structure embedded in LCP medium at 85% relative humidity"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1H8D", "A1ICR", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9I8L", "evidence_id": "EV-PDB-9I8L-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.831}, "provenance": {"deposit_id": "9I8L", "doi": "10.1002/chem.202500488", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9I8L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of a polyoxidovanadate/lysozyme adduct obtained when the protein is treated with [VIVO(acac)2</sub>] at 310 K"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "NDG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MP9", "evidence_id": "EV-PDB-9MP9-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "9MP9", "doi": "10.1107/S205225252500288X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MP9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mix & Quench Time Resolved Lysozyme - NAG1 Complex (1000 ms)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "NDG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MPA", "evidence_id": "EV-PDB-9MPA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "9MPA", "doi": "10.1107/S205225252500288X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MPA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mix & Quench Time Resolved Lysozyme - NAG1 Complex (2000 ms)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TOQ", "evidence_id": "EV-PDB-9TOQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "9TOQ", "doi": "10.1107/S2052252526003489", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TOQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature serial crystal structure of hen egg white lysozyme uncomplexed resting state at DLS I24 on silicon chips"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "NDG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V3P", "evidence_id": "EV-PDB-9V3P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.81}, "provenance": {"deposit_id": "9V3P", "doi": "10.1107/S1600576726000063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V3P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Time-Resolved mixing crystallography structure of 1 micrometer Lysozyme microcrystals with 452 mM N-Acetyl-D-glucosamine at 2.5 seconds delay"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "NDG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V3H", "evidence_id": "EV-PDB-9V3H-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "hewl-structures-native", "state_id": "HEWL-native", "who": "rule:hewl-structures-native"}], "molecule_id": "P00698", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.68}, "provenance": {"deposit_id": "9V3H", "doi": "10.1107/S1600576726000063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V3H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Time-Resolved mixing crystallography structure of 3-5 micrometers Lysozyme microcrystals with 226 mM N-Acetyl-D-glucosamine at 2 seconds delay"}
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{"conditions": {"applied_force_pn": null, "buffer": "40 mM Sodium Acetate", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4 nm.", "ph": 3.8, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDAC2/", "evidence_id": "EV-SASBDB-SASDAC2", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 1.47}, "provenance": {"deposit_id": "SASDAC2", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDAC2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Standard proteins"}
{"conditions": {"applied_force_pn": null, "buffer": "40 mM Sodium Acetate", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4 nm.", "ph": 3.8, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDAG2/", "evidence_id": "EV-SASBDB-SASDAG2", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 1.45}, "provenance": {"deposit_id": "SASDAG2", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDAG2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Standard proteins"}
{"conditions": {"applied_force_pn": null, "buffer": "40 mM Sodium Acetate pH 4.0, 50 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 4.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDCK8/", "evidence_id": "EV-SASBDB-SASDCK8", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.03, "unit": "nm", "value": 1.41}, "provenance": {"deposit_id": "SASDCK8", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDCK8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "WAXS benchmark on standard proteins"}
{"conditions": {"applied_force_pn": null, "buffer": "40 mM sodium acetate, 150 mM NaCl, 100 mM 5-methyl uridine", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.2 nm.", "ph": 3.8, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDJH3/", "evidence_id": "EV-SASBDB-SASDJH3", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.025, "unit": "nm", "value": 1.45}, "provenance": {"deposit_id": "SASDJH3", "doi": "10.1107/S2059798320010700", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDJH3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Improving data quality and expanding BioSAXS experiments to low-molecular-weight and low-concentration protein samples."}
{"conditions": {"applied_force_pn": null, "buffer": "0.2 M glycine-HCl, 80 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Fe3O4 nanoparticles; nominal diameter 10 nm (hydrodynamic diameter)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 70 nm.", "ph": 2.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 10 nm (hydrodynamic diameter)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDM44/", "evidence_id": "EV-SASBDB-SASDM44", "mappings": [], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.104, "unit": "nm", "value": 22.305}, "provenance": {"deposit_id": "SASDM44", "doi": "10.3390/molecules26164864", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDM44/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"}
{"conditions": {"applied_force_pn": null, "buffer": "0.2 M glycine-HCl, 80 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Fe3O4 nanoparticles; nominal diameter 30 nm (hydrodynamic diameter)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 95 nm.", "ph": 2.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 30 nm (hydrodynamic diameter)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDM54/", "evidence_id": "EV-SASBDB-SASDM54", "mappings": [], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.248, "unit": "nm", "value": 22.537}, "provenance": {"deposit_id": "SASDM54", "doi": "10.3390/molecules26164864", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDM54/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"}
{"conditions": {"applied_force_pn": null, "buffer": "0.2 M glycine-HCl, 80 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 90 nm.", "ph": 2.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDM64/", "evidence_id": "EV-SASBDB-SASDM64", "mappings": [], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.226, "unit": "nm", "value": 23.642}, "provenance": {"deposit_id": "SASDM64", "doi": "10.3390/molecules26164864", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDM64/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"}
{"conditions": {"applied_force_pn": null, "buffer": "0.2 M glycine-HCl, 80 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 75 nm.", "ph": 2.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "lysozyme amyloid fibril with Fe3O4 nanoparticles; nominal diameter 20 nm (hydrodynamic diameter)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDM74/", "evidence_id": "EV-SASBDB-SASDM74", "mappings": [], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.169, "unit": "nm", "value": 30.97}, "provenance": {"deposit_id": "SASDM74", "doi": "10.3390/molecules26164864", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDM74/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study"}
{"conditions": {"applied_force_pn": null, "buffer": "100 mM HEPES pH 7.5, 20 %(v/v) jeffamine M-600", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDM79/", "evidence_id": "EV-SASBDB-SASDM79", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.015, "unit": "nm", "value": 1.75}, "provenance": {"deposit_id": "SASDM79", "doi": "10.32607/actanaturae.11815", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDM79/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The Relationship of Precursor Cluster Concentration in a Saturated Crystallization Solution to Long-Range Order During the Transition to the Solid Phase."}
{"conditions": {"applied_force_pn": null, "buffer": "100 mM sodium acetate, pH 4.6, 2.0 M sodium formate", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 4.6, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDM89/", "evidence_id": "EV-SASBDB-SASDM89", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.071, "unit": "nm", "value": 2.15}, "provenance": {"deposit_id": "SASDM89", "doi": "10.32607/actanaturae.11815", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDM89/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The Relationship of Precursor Cluster Concentration in a Saturated Crystallization Solution to Long-Range Order During the Transition to the Solid Phase."}
{"conditions": {"applied_force_pn": null, "buffer": "200 mM K/Na tartrate, 100 mM tri-sodium citrate pH 5.6, 2.0 M ammonium sulfate", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 5.6, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDM99/", "evidence_id": "EV-SASBDB-SASDM99", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.039, "unit": "nm", "value": 2.35}, "provenance": {"deposit_id": "SASDM99", "doi": "10.32607/actanaturae.11815", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDM99/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The Relationship of Precursor Cluster Concentration in a Saturated Crystallization Solution to Long-Range Order During the Transition to the Solid Phase."}
{"conditions": {"applied_force_pn": null, "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.23 nm.", "ph": 3.8, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDMC2/", "evidence_id": "EV-SASBDB-SASDMC2", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.054, "unit": "nm", "value": 1.322}, "provenance": {"deposit_id": "SASDMC2", "doi": "10.1080/07391102.2021.1977704", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDMC2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."}
{"conditions": {"applied_force_pn": null, "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.29 nm.", "ph": 3.8, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDMD2/", "evidence_id": "EV-SASBDB-SASDMD2", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.03, "unit": "nm", "value": 1.396}, "provenance": {"deposit_id": "SASDMD2", "doi": "10.1080/07391102.2021.1977704", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDMD2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."}
{"conditions": {"applied_force_pn": null, "buffer": "40 mM NaOAc pH 3.8, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.52 nm.", "ph": 3.8, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Lysozyme C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDME2/", "evidence_id": "EV-SASBDB-SASDME2", "mappings": [{"confidence": "low", "justification": "SAXS of the protein alone in solution under native conditions; samples with partners and denatured samples are excluded.", "rule": "hewl-saxs-native", "state_id": "HEWL-native", "who": "rule:hewl-saxs-native"}], "molecule_id": "P00698", "observable": {"type": "radius_of_gyration", "uncertainty": 0.027, "unit": "nm", "value": 1.418}, "provenance": {"deposit_id": "SASDME2", "doi": "10.1080/07391102.2021.1977704", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDME2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Visualizing how inclusion of higher reciprocal space in SWAXS data analysis improves shape restoration of biomolecules: case of lysozyme."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/198L", "evidence_id": "EV-PDB-198L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "198L", "doi": "10.1006/jmbi.1996.0338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/198L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THERMODYNAMIC AND STRUCTURAL COMPENSATION IN \"SIZE-SWITCH\" CORE-REPACKING VARIANTS OF T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/197L", "evidence_id": "EV-PDB-197L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "197L", "doi": "10.1006/jmbi.1996.0338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/197L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THERMODYNAMIC AND STRUCTURAL COMPENSATION IN \"SIZE-SWITCH\" CORE-REPACKING VARIANTS OF T4 LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/195L", "evidence_id": "EV-PDB-195L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "195L", "doi": "10.1006/jmbi.1996.0338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/195L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THERMODYNAMIC AND STRUCTURAL COMPENSATION IN \"SIZE-SWITCH\" CORE-REPACKING VARIANTS OF T4 LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LYSOZYME (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/180L", "evidence_id": "EV-PDB-180L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "180L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/180L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/178L", "evidence_id": "EV-PDB-178L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "178L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/178L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Protein flexibility and adaptability seen in 25 crystal forms of T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/177L", "evidence_id": "EV-PDB-177L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "177L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/177L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Protein flexibility and adaptability seen in 25 crystal forms of T4 LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/175L", "evidence_id": "EV-PDB-175L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "175L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/175L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/173L", "evidence_id": "EV-PDB-173L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "173L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/173L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/172L", "evidence_id": "EV-PDB-172L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "172L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/172L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/171L", "evidence_id": "EV-PDB-171L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "171L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/171L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/170L", "evidence_id": "EV-PDB-170L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "170L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/170L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/167L", "evidence_id": "EV-PDB-167L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "167L", "doi": "10.1006/jmbi.1995.0396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/167L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/166L", "evidence_id": "EV-PDB-166L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "166L", "doi": "10.1006/jmbi.1994.0087", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/166L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/165L", "evidence_id": "EV-PDB-165L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "165L", "doi": "10.1006/jmbi.1994.0087", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/165L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DYE", "evidence_id": "EV-PDB-1DYE-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1DYE", "doi": "10.1006/jmbi.1994.1016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DYE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DYF", "evidence_id": "EV-PDB-1DYF-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1DYF", "doi": "10.1006/jmbi.1994.1016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DYF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1L95", "evidence_id": "EV-PDB-1L95-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1L95", "doi": "10.1006/jmbi.1993.1077", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1L95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1L97", "evidence_id": "EV-PDB-1L97-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1L97", "doi": "10.1016/0022-2836(92)90231-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1L97"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LYI", "evidence_id": "EV-PDB-1LYI-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1LYI", "doi": "10.1021/bi00129a006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LYI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LYJ", "evidence_id": "EV-PDB-1LYJ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1LYJ", "doi": "10.1021/bi00129a006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "HED", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1P37", "evidence_id": "EV-PDB-1P37-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.57}, "provenance": {"deposit_id": "1P37", "doi": "10.1016/S0022-2836(03)00856-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1P37"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 LYSOZYME CORE REPACKING BACK-REVERTANT L102M/CORE10"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/252L", "evidence_id": "EV-PDB-252L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "252L", "doi": "10.1006/jmbi.1997.1606", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/252L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OE4", "evidence_id": "EV-PDB-2OE4-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2OE4", "doi": "10.1073/pnas.0508224102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OE4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High Pressure Psuedo Wild Type T4 Lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1MR", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OTZ", "evidence_id": "EV-PDB-2OTZ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.07}, "provenance": {"deposit_id": "2OTZ", "doi": "10.1016/j.jmb.2007.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OTZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "N-methylaniline in complex with T4 Lysozyme L99A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MR3", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OU0", "evidence_id": "EV-PDB-2OU0-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "2OU0", "doi": "10.1016/j.jmb.2007.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OU0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1-methylpyrrole in complex with T4 Lysozyme L99A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["263", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RB2", "evidence_id": "EV-PDB-2RB2-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.463}, "provenance": {"deposit_id": "2RB2", "doi": "10.1016/j.jmb.2008.01.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RB2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "3-methylbenzylazide in complex with T4 lysozyme L99A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["261", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RB1", "evidence_id": "EV-PDB-2RB1-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2RB1", "doi": "10.1016/j.jmb.2008.01.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RB1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2-ethoxyphenol in complex with T4 lysozyme L99A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["260", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RB0", "evidence_id": "EV-PDB-2RB0-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "2RB0", "doi": "10.1016/j.jmb.2008.01.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2,6-difluorobenzylbromide complex with T4 lysozyme L99A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["259", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RAZ", "evidence_id": "EV-PDB-2RAZ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.641}, "provenance": {"deposit_id": "2RAZ", "doi": "10.1016/j.jmb.2008.01.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RAZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "4-(methylthio)nitrobenzene in complex with T4 lysozyme L99A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["258", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RAY", "evidence_id": "EV-PDB-2RAY-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.798}, "provenance": {"deposit_id": "2RAY", "doi": "10.1016/j.jmb.2008.01.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RAY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "beta-chlorophenetole in complex with T4 lysozyme L99A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Transcription factor ETV6,Endolysin (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2QB0", "evidence_id": "EV-PDB-2QB0-2", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "2QB0", "doi": "10.1110/ps.073074207", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2QB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NH4", "NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lysozyme (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2QAR", "evidence_id": "EV-PDB-2QAR-3", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "2QAR", "doi": "10.1110/ps.073074207", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2QAR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the 2TEL crystallization module fused to T4 lysozyme with a helical linker."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED", "MTN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Q9E", "evidence_id": "EV-PDB-2Q9E-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2Q9E", "doi": "10.1110/ps.073174008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Q9E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of spin-labeled T4 lysozyme mutant S44R1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "MTN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Q9D", "evidence_id": "EV-PDB-2Q9D-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "2Q9D", "doi": "10.1110/ps.073174008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Q9D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of spin-labeled T4 lysozyme mutant A41R1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MTN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OU9", "evidence_id": "EV-PDB-2OU9-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "2OU9", "doi": "10.1110/ps.062739107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OU9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Spin-labeled T4 Lysozyme Mutant T115R1/R119A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "MTN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OU8", "evidence_id": "EV-PDB-2OU8-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2OU8", "doi": "10.1110/ps.062739107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OU8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Spin-labeled T4 Lysozyme Mutant T115R1 at Room Temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OEA", "evidence_id": "EV-PDB-2OEA-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.01}, "provenance": {"deposit_id": "2OEA", "doi": "10.1016/j.jmb.2006.12.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-pressure structure of pseudo-WT T4 Lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OE9", "evidence_id": "EV-PDB-2OE9-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.01}, "provenance": {"deposit_id": "2OE9", "doi": "10.1016/j.jmb.2006.12.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OE9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-pressure structure of pseudo-WT T4 Lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lysozyme (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OE7", "evidence_id": "EV-PDB-2OE7-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2OE7", "doi": "10.1016/j.jmb.2006.12.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-Pressure T4 Lysozyme"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AZI", "CL", "HED", "MTN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3G3W", "evidence_id": "EV-PDB-3G3W-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3G3W", "doi": "10.1002/pro.96", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3G3W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of spin labeled T4 Lysozyme (T151R1) at 291 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CO3", "SO4", "TAM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GUI", "evidence_id": "EV-PDB-3GUI-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "3GUI", "doi": "10.1021/bi900685j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GUI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--Apo structure"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANL", "CA", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GUN", "evidence_id": "EV-PDB-3GUN-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "3GUN", "doi": "10.1021/bi900685j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GUN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--aniline binding"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "HED", "PIH", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3DNA", "evidence_id": "EV-PDB-3DNA-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3DNA", "doi": "10.1016/j.jmb.2008.10.086", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3DNA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Iodobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant (seleno version)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F3B", "HED", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3DN6", "evidence_id": "EV-PDB-3DN6-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3DN6", "doi": "10.1016/j.jmb.2008.10.086", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3DN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1,3,5-trifluoro-2,4,6-trichlorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BBF", "HED", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3DN2", "evidence_id": "EV-PDB-3DN2-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3DN2", "doi": "10.1016/j.jmb.2008.10.086", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3DN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Bromopentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3CDV", "evidence_id": "EV-PDB-3CDV-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.73}, "provenance": {"deposit_id": "3CDV", "doi": "10.1002/pro.94", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3CDV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["266", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RBP", "evidence_id": "EV-PDB-2RBP-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.467}, "provenance": {"deposit_id": "2RBP", "doi": "10.1016/j.jmb.2008.01.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RBP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2-(n-propylthio)ethanol in complex with T4 lysozyme L99A/M102Q"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["265", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RBO", "evidence_id": "EV-PDB-2RBO-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.29}, "provenance": {"deposit_id": "2RBO", "doi": "10.1016/j.jmb.2008.01.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RBO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2-nitrothiophene in complex with T4 lysozyme L99A/M102Q"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JZ0", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HT6", "evidence_id": "EV-PDB-3HT6-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.59}, "provenance": {"deposit_id": "3HT6", "doi": "10.1016/j.jmb.2009.09.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HT6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2-methylphenol in complex with T4 lysozyme L99A/M102Q"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JZ2", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HT8", "evidence_id": "EV-PDB-3HT8-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3HT8", "doi": "10.1016/j.jmb.2009.09.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HT8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "5-chloro-2-methylphenol in complex with T4 lysozyme L99A/M102Q"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "JZ3", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HT9", "evidence_id": "EV-PDB-3HT9-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "3HT9", "doi": "10.1016/j.jmb.2009.09.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HT9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2-methoxyphenol in complex with T4 lysozyme L99A/M102Q"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "JZ5", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HTD", "evidence_id": "EV-PDB-3HTD-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "3HTD", "doi": "10.1016/j.jmb.2009.09.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "(Z)-Thiophene-2-carboxaldoxime in complex with T4 lysozyme L99A/M102Q"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "JZ9", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HUA", "evidence_id": "EV-PDB-3HUA-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "3HUA", "doi": "10.1016/j.jmb.2009.09.049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HUA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "4,5,6,7-tetrahydroindole in complex with T4 lysozyme L99A/M102Q"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3L64", "evidence_id": "EV-PDB-3L64-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3L64", "doi": "10.1006/jmbi.1994.1016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3L64"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme S44E/WT*"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LZM", "evidence_id": "EV-PDB-3LZM-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3LZM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LZM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL STUDIES OF MUTANTS OF T4 LYSOZYME THAT ALTER HYDROPHOBIC STABILIZATION"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED", "PO4", "PYJ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HH6", "evidence_id": "EV-PDB-3HH6-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.25}, "provenance": {"deposit_id": "3HH6", "doi": "10.1002/anie.200903390", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HH6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "New azaborine compounds bind to the T4 lysozyme L99A cavity -ethylbenzene as control"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EPE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4W51", "evidence_id": "EV-PDB-4W51-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "4W51", "doi": "10.1073/pnas.1500806112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4W51"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A with No Ligand Bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "C-X-C chemokine receptor type 4/Endolysin chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4RWS", "evidence_id": "EV-PDB-4RWS-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "4RWS", "doi": "10.1126/science.1261064", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4RWS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of CXCR4 and viral chemokine antagonist vMIP-II complex (PSI Community Target)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Oxysterol-binding protein homolog 3,Endolysin,Oxysterol-binding protein homolog 3 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IAP", "evidence_id": "EV-PDB-4IAP-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "4IAP", "doi": "10.1016/j.str.2013.05.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IAP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1DV", "ACT", "BME", "HED", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I7S", "evidence_id": "EV-PDB-4I7S-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "4I7S", "doi": "10.1021/jm301823g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I7S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with 3-trifluoromethyl-5-methyl pyrazole bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1DU", "ACT", "BME", "HED", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I7R", "evidence_id": "EV-PDB-4I7R-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.52}, "provenance": {"deposit_id": "4I7R", "doi": "10.1021/jm301823g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I7R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with 2-(pyrazolo-1-yl) ethanol bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BME", "ES3", "HED", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I7P", "evidence_id": "EV-PDB-4I7P-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "4I7P", "doi": "10.1021/jm301823g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with 4-bromoimidazole bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BME", "HED", "IPH", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I7L", "evidence_id": "EV-PDB-4I7L-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.52}, "provenance": {"deposit_id": "4I7L", "doi": "10.1021/jm301823g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I7L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with phenol bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BME", "HED", "MBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I7K", "evidence_id": "EV-PDB-4I7K-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "4I7K", "doi": "10.1021/jm301823g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I7K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with toluene bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Sec-independent protein translocase protein TatC, Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4HTT", "evidence_id": "EV-PDB-4HTT-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.8}, "provenance": {"deposit_id": "4HTT", "doi": "10.1016/j.str.2013.03.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4HTT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Twin Arginine Translocase Receptor- TatC in DDM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EPE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Neurotensin receptor type 1, lysozyme chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GRV", "evidence_id": "EV-PDB-4GRV-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.802}, "provenance": {"deposit_id": "4GRV", "doi": "10.1038/nature11558", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GRV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of the neurotensin receptor NTS1 in complex with neurotensin (8-13)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GBR", "evidence_id": "EV-PDB-4GBR-2", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.993}, "provenance": {"deposit_id": "4GBR", "doi": "10.1371/journal.pone.0046039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GBR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pesticin, Lysozyme Chimera (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EXM", "evidence_id": "EV-PDB-4EXM-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "4EXM", "doi": "10.1073/pnas.1203472109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EXM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pesticin, Lysozyme Chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EPI", "evidence_id": "EV-PDB-4EPI-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.74}, "provenance": {"deposit_id": "4EPI", "doi": "10.1073/pnas.1203472109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EPI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of pesticin-T4 lysozyme hybrid stabilized by engineered disulfide bonds"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["0R1", "ACT", "BME", "HED", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EKS", "evidence_id": "EV-PDB-4EKS-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.64}, "provenance": {"deposit_id": "4EKS", "doi": "10.1073/pnas.1208076109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EKS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with Isoxazole Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BME", "HED", "NPO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EKQ", "evidence_id": "EV-PDB-4EKQ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.54}, "provenance": {"deposit_id": "4EKQ", "doi": "10.1073/pnas.1208076109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EKQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with 4-Nitrophenol Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BME", "HED", "NBZ", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EKP", "evidence_id": "EV-PDB-4EKP-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.64}, "provenance": {"deposit_id": "4EKP", "doi": "10.1073/pnas.1208076109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EKP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102H with Nitrobenzene Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EJ4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -195.15}, "construct": {"description": "Delta-type opioid receptor, Lysozyme chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EJ4", "evidence_id": "EV-PDB-4EJ4-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "4EJ4", "doi": "10.1038/nature11111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EJ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the delta opioid receptor bound to naltrindole"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["0HK", "EDT", "OLA", "OLC", "P6G", "PG6"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Muscarinic acetylcholine receptor M4,Endolysin,Endolysin,Muscarinic acetylcholine receptor M4 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DSG", "evidence_id": "EV-PDB-5DSG-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5DSG", "doi": "10.1038/nature17188", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DSG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the M4 muscarinic acetylcholine receptor (M4-mT4L) bound to tiotropium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["5MV", "OLA", "PE5", "TLA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Glucagon receptor,Endolysin,Glucagon receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EE7", "evidence_id": "EV-PDB-5EE7-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "5EE7", "doi": "10.1038/nature17414", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human glucagon receptor (GCGR) in complex with the antagonist MK-0893"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Phosphatidylinositol 4-kinase type 2-alpha,Endolysin,Phosphatidylinositol 4-kinase type 2-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EUT", "evidence_id": "EV-PDB-5EUT-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.802}, "provenance": {"deposit_id": "5EUT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EUT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of phosphatidyl inositol 4-kinase II alpha in the apo state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EYC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Endolysin,Immunoglobulin G-binding protein A,Endolysin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EWX", "evidence_id": "EV-PDB-5EWX-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5EWX", "doi": "10.1038/ncomms11031", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EWX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "HED", "MTN", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "ENDOLYSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5G27", "evidence_id": "EV-PDB-5G27-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.61}, "provenance": {"deposit_id": "5G27", "doi": "10.1021/JACS.6B05507", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5G27"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at Room Temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endothelin Receptor Subtype-B (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GLH", "evidence_id": "EV-PDB-5GLH-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "5GLH", "doi": "10.1038/nature19319", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GLH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human endothelin receptor type-B in complex with ET-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "mutated and truncated T4 lysozyme (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5I14", "evidence_id": "EV-PDB-5I14-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.745}, "provenance": {"deposit_id": "5I14", "doi": "10.1002/pro.3162", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5I14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Truncated and mutated T4 lysozyme"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AZI", "BME", "CL", "K", "MTN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JDT", "evidence_id": "EV-PDB-5JDT-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.0}, "provenance": {"deposit_id": "5JDT", "doi": "10.1021/jacs.6b05507", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JDT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPD", "NA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Superkiller protein 7,Endolysin (chains K)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JEA", "evidence_id": "EV-PDB-5JEA-11", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "5JEA", "doi": "10.1016/j.molcel.2016.05.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "K", "PO4", "V1A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JGN", "evidence_id": "EV-PDB-5JGN-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.534}, "provenance": {"deposit_id": "5JGN", "doi": "10.1021/acs.biochem.6b00608", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JGN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Spin-Labeled T4 Lysozyme Construct I9V1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "HEZ", "K", "PO4", "V1A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JGR", "evidence_id": "EV-PDB-5JGR-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.46}, "provenance": {"deposit_id": "5JGR", "doi": "10.1021/acs.biochem.6b00608", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JGR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Spin-Labeled T4 Lysozyme Construct K43V1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "K", "PO4", "V1A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JGU", "evidence_id": "EV-PDB-5JGU-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.468}, "provenance": {"deposit_id": "5JGU", "doi": "10.1021/acs.biochem.6b00608", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JGU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Spin-Labeled T4 Lysozyme Construct R119V1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "HEZ", "K", "V1A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JGV", "evidence_id": "EV-PDB-5JGV-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.732}, "provenance": {"deposit_id": "5JGV", "doi": "10.1021/acs.biochem.6b00608", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JGV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Spin-Labeled T4 Lysozyme Construct A73V1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "K", "PO4", "V1A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JGX", "evidence_id": "EV-PDB-5JGX-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.533}, "provenance": {"deposit_id": "5JGX", "doi": "10.1021/acs.biochem.6b00608", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JGX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Spin-Labeled T4 Lysozyme Construct V131V1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "HEZ", "K", "PO4", "V1A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JGZ", "evidence_id": "EV-PDB-5JGZ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.534}, "provenance": {"deposit_id": "5JGZ", "doi": "10.1021/acs.biochem.6b00608", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JGZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Spin-Labeled T4 Lysozyme Construct T151V1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAU", "CLR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Endolysin,Beta-2 adrenergic receptor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JQH", "evidence_id": "EV-PDB-5JQH-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "5JQH", "doi": "10.1038/nature18636", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JQH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of beta2 adrenoceptor bound to carazolol and inactive-state stabilizing nanobody, Nb60"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6OQ", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JWS", "evidence_id": "EV-PDB-5JWS-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "5JWS", "doi": "10.1021/jacs.6b06566", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JWS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A with 1-Hydro-2-ethyl-1,2-azaborine Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BNZ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JWT", "evidence_id": "EV-PDB-5JWT-1", "mappings": [{"confidence": "high", "justification": "Title names L99A and benzene (BNZ) is bound in the cavity.", "rule": "t4l-l99a-benzene", "state_id": "T4L-L99A-benzene", "who": "rule:t4l-l99a-benzene"}], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.41}, "provenance": {"deposit_id": "5JWT", "doi": "10.1021/jacs.6b06566", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JWT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102Q with Benzene Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6OQ", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JWW", "evidence_id": "EV-PDB-5JWW-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.47}, "provenance": {"deposit_id": "5JWW", "doi": "10.1021/jacs.6b06566", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JWW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102Q with 1-Hydro-2-ethyl-1,2-azaborine Bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KI2", "evidence_id": "EV-PDB-5KI2-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "5KI2", "doi": "10.1021/acs.biochem.7b00022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KI2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PSEUDO T4 LYSOZYME MUTANT - Y18PHE-METHYL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KI3", "evidence_id": "EV-PDB-5KI3-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "5KI3", "doi": "10.1021/acs.biochem.7b00022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KI3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PSEUDO T4 LYSOZYME MUTANT - Y18PHE-BR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KI8", "evidence_id": "EV-PDB-5KI8-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "5KI8", "doi": "10.1021/acs.biochem.7b00022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KI8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PSEUDO T4 LYSOZYME MUTANT - Y88PHE-BR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "HED", "K", "PO4", "RXR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LWO", "evidence_id": "EV-PDB-5LWO-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.183}, "provenance": {"deposit_id": "5LWO", "doi": "10.1021/acs.jpclett.6b02971", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LWO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at 100K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6XQ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Free fatty acid receptor 1,Lysozyme,Free fatty acid receptor 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KW2", "evidence_id": "EV-PDB-5KW2-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "5KW2", "doi": "10.1038/s41467-017-01240-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KW2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The extra-helical binding site of GPR40 and the structural basis for allosteric agonism and incretin stimulation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KIO", "evidence_id": "EV-PDB-5KIO-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.63}, "provenance": {"deposit_id": "5KIO", "doi": "10.1021/acs.biochem.7b00022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KIO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PSEUDO T4 LYSOZYME MUTANT - Y18PHE-I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KII", "evidence_id": "EV-PDB-5KII-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.56}, "provenance": {"deposit_id": "5KII", "doi": "10.1021/acs.biochem.7b00022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KII"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PSEUDO T4 LYSOZYME MUTANT - Y88PHE-METHYL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KIG", "evidence_id": "EV-PDB-5KIG-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "5KIG", "doi": "10.1021/acs.biochem.7b00022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KIG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PSEUDO T4 LYSOZYME MUTANT - Y88F"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KI1", "evidence_id": "EV-PDB-5KI1-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.46}, "provenance": {"deposit_id": "5KI1", "doi": "10.1021/acs.biochem.7b00022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KI1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PSEUDO T4 LYSOZYME MUTANT - Y18F"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PYJ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JWV", "evidence_id": "EV-PDB-5JWV-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "5JWV", "doi": "10.1021/jacs.6b06566", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JWV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A/M102Q with Ethylbenzene Bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Flagellar assembly protein H,Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4YXC", "evidence_id": "EV-PDB-4YXC-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "4YXC", "doi": "10.1038/ncomms8125", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4YXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex of FliM(SPOA)::FliN fusion protein and FliH(APAR)::T4lysozyme fusion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "T4 LYSOZYME (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LZM", "evidence_id": "EV-PDB-5LZM-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "5LZM", "doi": "10.1002/prot.340100103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LZM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["8TZ", "NA", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme,Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated receptor 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NDD", "evidence_id": "EV-PDB-5NDD-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.801}, "provenance": {"deposit_id": "5NDD", "doi": "10.1038/nature22309", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NDD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in complex with AZ8838 at 2.8 angstrom resolution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5V7E", "evidence_id": "EV-PDB-5V7E-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.36}, "provenance": {"deposit_id": "5V7E", "doi": "10.1021/acs.biochem.8b00603", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5V7E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme Y18Ymcl"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HED"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5V7F", "evidence_id": "EV-PDB-5V7F-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "5V7F", "doi": "10.1021/acs.biochem.8b00603", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5V7F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme Y18Ymi"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme, ESX-1 secretion-associated protein EspG1 chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VBA", "evidence_id": "EV-PDB-5VBA-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.27}, "provenance": {"deposit_id": "5VBA", "doi": "10.1016/j.jmb.2018.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VBA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of EspG1 chaperone from the type VII (ESX-1) secretion system determined with the assistance of N-terminal T4 lysozyme fusion"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["97V"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Glucagon-like peptide 1 receptor, Endolysin chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VEX", "evidence_id": "EV-PDB-5VEX-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "5VEX", "doi": "10.1038/nature22378", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VEX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the human GLP-1 receptor complex with NNC0640"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VNQ", "evidence_id": "EV-PDB-5VNQ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "5VNQ", "doi": "10.1002/pro.3231", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VNQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "neutron", "title": "Neutron crystallographic structure of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at cryogenic temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "HED", "NA", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VNR", "evidence_id": "EV-PDB-5VNR-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.631}, "provenance": {"deposit_id": "5VNR", "doi": "10.1002/pro.3231", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at cryogenic temperature"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Endolysin,Rhodopsin,S-arrestin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W0P", "evidence_id": "EV-PDB-5W0P-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.013}, "provenance": {"deposit_id": "5W0P", "doi": "10.1016/j.cell.2017.07.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W0P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of rhodopsin bound to visual arrestin determined by X-ray free electron laser"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["OLC", "UKA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Human A2a adenosine receptor T4L chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WF5", "evidence_id": "EV-PDB-5WF5-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5WF5", "doi": "10.1016/j.str.2017.12.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WF5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Agonist bound human A2a adenosine receptor with D52N mutation at 2.60 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["OLC", "UKA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Human A2a adenosine receptor T4L chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WF6", "evidence_id": "EV-PDB-5WF6-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "5WF6", "doi": "10.1016/j.str.2017.12.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WF6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Agonist bound human A2a adenosine receptor with S91A mutation at 2.90 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["97V", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Glucagon receptor,Endolysin,Glucagon receptor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5XEZ", "evidence_id": "EV-PDB-5XEZ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "5XEZ", "doi": "10.1038/nature22363", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5XEZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Full-length glucagon class B G protein-coupled receptor"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IHP", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "COP9 signalosome complex subunit 2,Endolysin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A73", "evidence_id": "EV-PDB-6A73-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.447}, "provenance": {"deposit_id": "6A73", "doi": "10.1073/pnas.1911998117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A73"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex structure of CSN2 with IP6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Endolysin,Autophagy-related protein 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A9E", "evidence_id": "EV-PDB-6A9E-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.205}, "provenance": {"deposit_id": "6A9E", "doi": "10.1038/s41594-019-0203-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A9E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N-terminal domain of Atg2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PEE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Endolysin,Autophagy-related protein 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A9J", "evidence_id": "EV-PDB-6A9J-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "6A9J", "doi": "10.1038/s41594-019-0203-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PE-bound N-terminal domain of Atg2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DOJ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin, DCN1-like protein 1 chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BG3", "evidence_id": "EV-PDB-6BG3-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.05}, "provenance": {"deposit_id": "6BG3", "doi": "10.1021/acs.jmedchem.7b01277", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of (3S,4S)-1-benzyl-4-(3-(3-(trifluoromethyl)phenyl)ureido)piperidin-3-yl acetate bound to DCN1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DQD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin, DCN1-like protein 1 chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BG5", "evidence_id": "EV-PDB-6BG5-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "6BG5", "doi": "10.1021/acs.jmedchem.7b01277", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BG5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of 1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-(1-propylpiperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea bound to DCN1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EPE", "OLA", "PO4", "QK2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Muscarinic acetylcholine receptor M1,Endolysin,Muscarinic acetylcholine receptor M1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZG9", "evidence_id": "EV-PDB-6ZG9-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6ZG9", "doi": "10.1016/j.cell.2021.11.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZG9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of M1-StaR-T4L in complex with GSK1034702 at 2.5A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DWS", "evidence_id": "EV-PDB-7DWS-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7DWS", "doi": "10.1016/j.biomaterials.2021.120895", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DWS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of T4 Lysozyme I3C/C54T/R125C/E128C complex with Zinc ions"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cholecystokinin receptor type A,Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7F8X", "evidence_id": "EV-PDB-7F8X-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7F8X", "doi": "10.1038/s41589-021-00866-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7F8X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the cholecystokinin receptor CCKAR in complex with NN9056"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1OZ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "fusion protein of Cholecystokinin receptor type A and Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7F8Y", "evidence_id": "EV-PDB-7F8Y-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7F8Y", "doi": "10.1038/s41589-021-00866-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7F8Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the cholecystokinin receptor CCKAR in complex with devazepide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L37", "evidence_id": "EV-PDB-7L37-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.439}, "provenance": {"deposit_id": "7L37", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L37"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - Apo - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L38", "evidence_id": "EV-PDB-7L38-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.33}, "provenance": {"deposit_id": "7L38", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L38"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - Apo - cryo"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "MBN", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L39", "evidence_id": "EV-PDB-7L39-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "7L39", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L39"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - toluene - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MBN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3A", "evidence_id": "EV-PDB-7L3A-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.11}, "provenance": {"deposit_id": "7L3A", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - toluene - cryo"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "PIH", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3B", "evidence_id": "EV-PDB-7L3B-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.27}, "provenance": {"deposit_id": "7L3B", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - iodobenzene - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "OXE", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3C", "evidence_id": "EV-PDB-7L3C-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.31}, "provenance": {"deposit_id": "7L3C", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - o-xylene - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "TRS", "XQJ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3D", "evidence_id": "EV-PDB-7L3D-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "7L3D", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - 3-iodotoluene - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "TRS", "XQJ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3E", "evidence_id": "EV-PDB-7L3E-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.13}, "provenance": {"deposit_id": "7L3E", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - 3-iodotoluene - cryo"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "TRS", "XQM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3F", "evidence_id": "EV-PDB-7L3F-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.49}, "provenance": {"deposit_id": "7L3F", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - 4-iodotoluene - RT"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "PYJ", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3H", "evidence_id": "EV-PDB-7L3H-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.39}, "provenance": {"deposit_id": "7L3H", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - ethylbenzene - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3H0", "CL", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3I", "evidence_id": "EV-PDB-7L3I-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.46}, "provenance": {"deposit_id": "7L3I", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - propylbenzene - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "J0Z", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3J", "evidence_id": "EV-PDB-7L3J-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.49}, "provenance": {"deposit_id": "7L3J", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - benzylacetate - RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "CL", "J0Z", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3K", "evidence_id": "EV-PDB-7L3K-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.11}, "provenance": {"deposit_id": "7L3K", "doi": "10.1039/d1sc02751d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 Lysozyme L99A - benzylacetate - cryo"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "TRS", "Y7V"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LOA", "evidence_id": "EV-PDB-7LOA-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.07}, "provenance": {"deposit_id": "7LOA", "doi": "10.1073/pnas.2106195118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LOA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme mutant L99A in complex with 3-fluoroiodobenzene"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "TRS", "ZNV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LOB", "evidence_id": "EV-PDB-7LOB-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "7LOB", "doi": "10.1073/pnas.2106195118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LOB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme mutant L99A in complex with 1-fluoro-2-[(prop-2-en-1-yl)oxy]benzene"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "TRS", "Y87"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LOC", "evidence_id": "EV-PDB-7LOC-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.16}, "provenance": {"deposit_id": "7LOC", "doi": "10.1073/pnas.2106195118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LOC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme mutant L99A in complex with 1-bromanyl-4-fluoranyl-benzene"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "TRS", "Y8D"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LOD", "evidence_id": "EV-PDB-7LOD-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.02}, "provenance": {"deposit_id": "7LOD", "doi": "10.1073/pnas.2106195118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LOD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme mutant L99A in complex with 1-fluoranyl-4-iodanyl-benzene"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "TRS", "Y8G"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LOF", "evidence_id": "EV-PDB-7LOF-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.05}, "provenance": {"deposit_id": "7LOF", "doi": "10.1073/pnas.2106195118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LOF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme mutant L99A in complex with 2-butylthiophene"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EPE", "Y8M"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LOJ", "evidence_id": "EV-PDB-7LOJ-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "7LOJ", "doi": "10.1073/pnas.2106195118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LOJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme mutant L99A in complex with 4-(3-phenylpropyl)aniline"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TRS", "YGM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lysozyme (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LX9", "evidence_id": "EV-PDB-7LX9-1", "mappings": [], "molecule_id": "P00720", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.19}, "provenance": {"deposit_id": "7LX9", "doi": "10.1073/pnas.2106195118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "T4 lysozyme mutant L99A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UUB", "evidence_id": "EV-PDB-1UUB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1UUB", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UUB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of a truncated bovine pancreatic trypsin inhibitor mutant, 3-58 BPTI (K15R, R17A, R42S)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pancreatic trypsin inhibitor (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YLC", "evidence_id": "EV-PDB-1YLC-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1YLC", "doi": "10.1016/j.jmb.2007.10.084", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YLC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Trypsin/BPTI complex mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pancreatic trypsin inhibitor (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YKT", "evidence_id": "EV-PDB-1YKT-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1YKT", "doi": "10.1016/j.jmb.2007.10.084", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YKT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Trypsin/Bpti complex mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TPA", "evidence_id": "EV-PDB-1TPA-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1TPA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TPA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1T8N", "evidence_id": "EV-PDB-1T8N-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "1T8N", "doi": "10.1016/j.jmb.2004.09.088", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1T8N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE P1 THR BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 35.85}, "construct": {"description": "PANCREATIC TRYPSIN INHIBITOR (chains 5)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OA6", "evidence_id": "EV-PDB-1OA6-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1OA6", "doi": "10.1110/PS.0242103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OA6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "The solution structure of bovine pancreatic trypsin inhibitor at high pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 35.85}, "construct": {"description": "PANCREATIC TRYPSIN INHIBITOR (chains 5)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OA5", "evidence_id": "EV-PDB-1OA5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1OA5", "doi": "10.1110/PS.0242103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OA5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "The solution structure of bovine pancreatic trypsin inhibitor at high pressure"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BTI", "evidence_id": "EV-PDB-1BTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1BTI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains P,Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BTH", "evidence_id": "EV-PDB-1BTH-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1BTH", "doi": "10.1093/emboj/16.11.2977", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BTH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BPT", "evidence_id": "EV-PDB-1BPT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1BPT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BPT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CREVICE-FORMING MUTANTS OF BPTI: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AAL", "evidence_id": "EV-PDB-1AAL-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1AAL", "doi": "10.1002/prot.340140109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AAL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL EFFECTS INDUCED BY MUTAGENESIS AFFECTED BY CRYSTAL PACKING FACTORS: THE STRUCTURE OF A 30-51 DISULFIDE MUTANT OF BASIC PANCREATIC TRYPSIN INHIBITOR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pancreatic trypsin inhibitor (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YLD", "evidence_id": "EV-PDB-1YLD-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1YLD", "doi": "10.1016/j.jmb.2007.10.084", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YLD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Trypsin/BPTI complex mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains E,F,G,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2R9P", "evidence_id": "EV-PDB-2R9P-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "2R9P", "doi": "10.1074/jbc.M708268200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2R9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor(BPTI)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PROTEIN (PANCREATIC TRYPSIN INHIBITOR) (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3BTT", "evidence_id": "EV-PDB-3BTT-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3BTT", "doi": "10.1006/jmbi.1999.2654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3BTT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PROTEIN (BOVINE PANCREATIC TRYPSIN INHIBITOR) (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3BTW", "evidence_id": "EV-PDB-3BTW-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "3BTW", "doi": "10.1006/jmbi.1999.2654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3BTW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EDO", "PG4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FP6", "evidence_id": "EV-PDB-3FP6-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.49}, "provenance": {"deposit_id": "3FP6", "doi": "10.1073/pnas.0902463106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FP6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Anionic trypsin in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.49 A resolution limit"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EDO", "PG4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains J)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FP7", "evidence_id": "EV-PDB-3FP7-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.46}, "provenance": {"deposit_id": "3FP7", "doi": "10.1073/pnas.0902463106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FP7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EDO", "PG4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FP7", "evidence_id": "EV-PDB-3FP7-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.46}, "provenance": {"deposit_id": "3FP7", "doi": "10.1073/pnas.0902463106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FP7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "HG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LDI", "evidence_id": "EV-PDB-3LDI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "3LDI", "doi": "10.1016/j.bbrc.2010.05.113", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LDI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "branched: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LDJ", "evidence_id": "EV-PDB-3LDJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3LDJ", "doi": "10.1016/j.bbrc.2010.05.113", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LDM", "evidence_id": "EV-PDB-3LDM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "3LDM", "doi": "10.1016/j.bbrc.2010.05.113", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LDM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OTJ", "evidence_id": "EV-PDB-3OTJ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "3OTJ", "doi": "10.1107/S0907444910053382", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "neutron", "title": "A Crystal Structure of Trypsin Complexed with BPTI (Bovine Pancreatic Trypsin Inhibitor) by X-ray/Neutron Joint Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pancreatic trypsin inhibitor (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3P92", "evidence_id": "EV-PDB-3P92-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5992}, "provenance": {"deposit_id": "3P92", "doi": "10.1042/BJ20110788", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3P92"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor variant (BPTI-K15R/R17G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TGI", "evidence_id": "EV-PDB-3TGI-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3TGI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TGI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "WILD-TYPE RAT ANIONIC TRYPSIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TGJ", "evidence_id": "EV-PDB-3TGJ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "3TGJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TGJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "S195A TRYPSINOGEN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "PANCREATIC TRYPSIN INHIBITOR (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TGK", "evidence_id": "EV-PDB-3TGK-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3TGK", "doi": "10.1110/ps.44101", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TGK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "TRYPSINOGEN MUTANT D194N AND DELETION OF ILE 16-VAL 17 COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3U1J", "evidence_id": "EV-PDB-3U1J-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3U1J", "doi": "10.1128/JVI.06225-11", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3U1J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Aprotinin bound to Dengue virus protease"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pancreatic trypsin inhibitor (chains C,E,F,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DG4", "evidence_id": "EV-PDB-4DG4-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "4DG4", "doi": "10.1002/pro.2097", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DG4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human mesotrypsin-S39Y complexed with bovine pancreatic trypsin inhibitor (BPTI)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PTI", "evidence_id": "EV-PDB-4PTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4PTI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4", "VAL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4TPI", "evidence_id": "EV-PDB-4TPI-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "4TPI", "doi": "10.1111/j.1432-1033.1984.tb08447.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4TPI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE REFINED 2.2-ANGSTROMS (0.22-NM) X-RAY CRYSTAL STRUCTURE OF THE TERNARY COMPLEX FORMED BY BOVINE TRYPSINOGEN, VALINE-VALINE AND THE ARG15 ANALOGUE OF BOVINE PANCREATIC TRYPSIN INHIBITOR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Y0Y", "evidence_id": "EV-PDB-4Y0Y-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.25}, "provenance": {"deposit_id": "4Y0Y", "doi": "10.1039/c4sc03227f", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Y0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Trypsin in complex with with BPTI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Y0Z", "evidence_id": "EV-PDB-4Y0Z-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.37}, "provenance": {"deposit_id": "4Y0Z", "doi": "10.1039/c4sc03227f", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Y0Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Trypsin in complex with with BPTI mutant AMINOBUTYRIC ACID"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PANCREATIC TRYPSIN INHIBITOR (chains I,J)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BNR", "evidence_id": "EV-PDB-4BNR-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4BNR", "doi": "10.1111/FEBS.12491", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Extremely stable complex of crayfish trypsin with bovine trypsin inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Bovine Pancreatic Trypsin Inhibitor (chains A,B,C,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WNY", "evidence_id": "EV-PDB-3WNY-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "3WNY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WNY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A simplified BPTI variant with poly Lys amino acid tag (C3K) at the C-terminus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ILE", "SO4", "VAL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TPI", "evidence_id": "EV-PDB-3TPI-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3TPI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TPI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pancreatic trypsin inhibitor (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3P95", "evidence_id": "EV-PDB-3P95-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.2991}, "provenance": {"deposit_id": "3P95", "doi": "10.1042/BJ20110788", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3P95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor variant (BPTI-K15R/R17D)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I,J)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GYM", "evidence_id": "EV-PDB-3GYM-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "3GYM", "doi": "10.1002/pro.118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Prostasin in Complex with Aprotinin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EDO", "PG4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FP8", "evidence_id": "EV-PDB-3FP8-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.46}, "provenance": {"deposit_id": "3FP8", "doi": "10.1073/pnas.0902463106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.46 A resolution limit"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZJX", "evidence_id": "EV-PDB-2ZJX-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.09}, "provenance": {"deposit_id": "2ZJX", "doi": "10.1073/pnas.0802699105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ZJX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Bovine pancreatic trypsin inhibitor (BPTI) containing only the [5,55] disulfide bond"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EDO", "NA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2FI5", "evidence_id": "EV-PDB-2FI5-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "2FI5", "doi": "10.1016/j.jmb.2008.07.063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2FI5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a BPTI variant (Cys38->Ser) in complex with trypsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EDO", "NA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2FI4", "evidence_id": "EV-PDB-2FI4-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "2FI4", "doi": "10.1016/j.jmb.2008.07.063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2FI4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a BPTI variant (Cys14->Ser) in complex with trypsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EDO", "NA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2FI3", "evidence_id": "EV-PDB-2FI3-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "2FI3", "doi": "10.1016/j.jmb.2008.07.063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2FI3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a BPTI variant (Cys14->Ser, Cys38->Ser) in complex with trypsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Y10", "evidence_id": "EV-PDB-4Y10-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.37}, "provenance": {"deposit_id": "4Y10", "doi": "10.1039/c4sc03227f", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Y10"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4-difluorobutanoic acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JB4", "evidence_id": "EV-PDB-5JB4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "5JB4", "doi": "10.1038/srep41205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A simplified BPTI variant containing 21 alanines out 58 of residues"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JB5", "evidence_id": "EV-PDB-5JB5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "5JB5", "doi": "10.1038/srep41205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A simplified BPTI variant containing 22 alanines out of 58 residues"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JB7", "evidence_id": "EV-PDB-5JB7-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "5JB7", "doi": "10.1038/srep41205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JB7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A simplified BPTI variant containing 24 alanines out of 58 residues"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4", "UNX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5PTI", "evidence_id": "EV-PDB-5PTI-1", "mappings": [{"confidence": "high", "justification": "Representative native structure; title and UniProt mapping checked against RCSB.", "rule": "curator_assignment", "state_id": "BPTI-native", "who": "curator:draft (unreviewed)"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.0}, "provenance": {"deposit_id": "5PTI", "doi": "10.1016/S0022-2836(84)80006-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5PTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT OF CRYSTAL FORM II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -172.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5XX2", "evidence_id": "EV-PDB-5XX2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.12}, "provenance": {"deposit_id": "5XX2", "doi": "10.1111/febs.14941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5XX2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A BPTI-[5,55] variant with C14GA38L mutations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -172.0}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5XX4", "evidence_id": "EV-PDB-5XX4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.67}, "provenance": {"deposit_id": "5XX4", "doi": "10.1111/febs.14941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5XX4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A BPTI-[5,55] variant with C14GA38K mutations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -172.0}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5XX5", "evidence_id": "EV-PDB-5XX5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.38}, "provenance": {"deposit_id": "5XX5", "doi": "10.1111/febs.14941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5XX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A BPTI-[5,55] variant with C14GA38I mutations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -172.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5XX6", "evidence_id": "EV-PDB-5XX6-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.31}, "provenance": {"deposit_id": "5XX6", "doi": "10.1016/j.bbrc.2017.08.161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5XX6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hetero-micro-seeding: Crystal structure of BPTI-[5,55]C14GA38I variant using micro-seeds from -C14GA38G variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -172.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5XX7", "evidence_id": "EV-PDB-5XX7-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.38}, "provenance": {"deposit_id": "5XX7", "doi": "10.1016/j.bbrc.2017.08.161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5XX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hetero-micro-seeding: Crystal structure of BPTI-[5,55]C14GA38I variant using micro-seeds from -C14GA38I variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -172.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5XX8", "evidence_id": "EV-PDB-5XX8-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "5XX8", "doi": "10.1016/j.bbrc.2017.08.161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5XX8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hetero-micro-seeding: Crystal structure of BPTI-[555]C14GA38I variant using micro-seeds from -C14GA38L variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PANCREATIC TRYPSIN INHIBITOR PRECURSOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PTI", "evidence_id": "EV-PDB-6PTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "6PTI", "doi": "10.1016/0022-2836(87)90294-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF FORM III CRYSTALS OF BOVINE PANCREATIC TRYPSIN INHIBITOR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PTI", "evidence_id": "EV-PDB-7PTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "7PTI", "doi": "10.1093/protein/3.7.591", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL EFFECTS INDUCED BY REMOVAL OF A DISULFIDE BRIDGE. THE X-RAY STRUCTURE OF THE C30A(SLASH)C51A MUTANT OF BASIC PANCREATIC TRYPSIN INHIBITOR AT 1.6 ANGSTROMS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PTI", "evidence_id": "EV-PDB-8PTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "8PTI", "doi": "10.1016/0022-2836(91)90115-M", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF A Y35G MUTANT OF BOVINE PANCREATIC TRYPSIN INHIBITOR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BOVINE PANCREATIC TRYPSIN INHIBITOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PTI", "evidence_id": "EV-PDB-9PTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.22}, "provenance": {"deposit_id": "9PTI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BASIC PANCREATIC TRYPSIN INHIBITOR (MET 52 OXIDIZED)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains D,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QIT", "evidence_id": "EV-PDB-7QIT-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "7QIT", "doi": "10.1039/d2cb00018k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QIT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE P1 trifluoroethylglycine (TfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains D,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QIS", "evidence_id": "EV-PDB-7QIS-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "7QIS", "doi": "10.1039/d2cb00018k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QIS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE P1 difluoroethylglycine (DfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains D,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QIR", "evidence_id": "EV-PDB-7QIR-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "7QIR", "doi": "10.1039/d2cb00018k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QIR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE P1 monofluorethylglycine(MfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pancreatic trypsin inhibitor (chains D,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QIQ", "evidence_id": "EV-PDB-7QIQ-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "bpti-structures-native", "state_id": "BPTI-native", "who": "rule:bpti-structures-native"}], "molecule_id": "P00974", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "7QIQ", "doi": "10.1039/d2cb00018k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QIQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE P1 aminobutanoic acid (ABU) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "H-RAS (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BKD", "evidence_id": "EV-PDB-1BKD-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1BKD", "doi": "10.1038/28548", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BKD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "COMPLEX OF HUMAN H-RAS WITH HUMAN SOS-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CRP", "evidence_id": "EV-PDB-1CRP-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1CRP", "doi": "10.1021/bi00178a008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CRP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CRQ", "evidence_id": "EV-PDB-1CRQ-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1CRQ", "doi": "10.1021/bi00178a008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CRQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CRR", "evidence_id": "EV-PDB-1CRR-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1CRR", "doi": "10.1021/bi00178a008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CRR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN (TRANSFORMING PROTEIN P21/H-RAS-1) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CTQ", "evidence_id": "EV-PDB-1CTQ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.26}, "provenance": {"deposit_id": "1CTQ", "doi": "10.1016/S0969-2126(00)80021-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CTQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAG", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1GNQ", "evidence_id": "EV-PDB-1GNQ-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1GNQ", "doi": "10.1006/jmbi.1995.0541", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1GNQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAG", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1GNR", "evidence_id": "EV-PDB-1GNR-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1GNR", "doi": "10.1006/jmbi.1995.0541", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1GNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TRANSFORMING PROTEIN P21/H-RAS-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HE8", "evidence_id": "EV-PDB-1HE8-2", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "1HE8", "doi": "10.1016/S0092-8674(00)00196-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ras G12V - PI 3-kinase gamma complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "TRANSFORMING PROTEIN P21/H-RAS-1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IAQ", "evidence_id": "EV-PDB-1IAQ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "1IAQ", "doi": "10.1073/pnas.081441398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IAQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TRANSFORMING PROTEIN P21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IOZ", "evidence_id": "EV-PDB-1IOZ-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1IOZ", "doi": "10.1023/A:1013203532303", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IOZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the C-HA-RAS Protein Prepared by the Cell-Free Synthesis"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GCP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "C-HA-RAS (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JAH", "evidence_id": "EV-PDB-1JAH-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1JAH", "doi": "10.1006/jmbi.1996.0814", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JAH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MAGNESIUM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GCP", "MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "C-HA-RAS (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JAI", "evidence_id": "EV-PDB-1JAI-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1JAI", "doi": "10.1006/jmbi.1996.0814", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JAI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'-[BETA,GAMMA-METHYLENE] TRIPHOSPHATE AND MANGANESE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "Transforming protein P21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1K8R", "evidence_id": "EV-PDB-1K8R-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "1K8R", "doi": "10.1016/S0969-2126(01)00674-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1K8R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Ras-Bry2RBD complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein P21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LF0", "evidence_id": "EV-PDB-1LF0-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1LF0", "doi": "10.1073/pnas.192453199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LF0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of RasA59G in the GTP-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein P21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LF5", "evidence_id": "EV-PDB-1LF5-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1LF5", "doi": "10.1073/pnas.192453199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LF5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of RasA59G in the GDP-bound Form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -181.15}, "construct": {"description": "RAS (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LFD", "evidence_id": "EV-PDB-1LFD-2", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1LFD", "doi": "10.1038/nsb0698-422", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LFD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE ACTIVE RAS PROTEIN COMPLEXED WITH THE RAS-INTERACTING DOMAIN OF RALGDS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NVV", "evidence_id": "EV-PDB-1NVV-2", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.18}, "provenance": {"deposit_id": "1NVV", "doi": "10.1016/S0092-8674(03)00149-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NVV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NVV", "evidence_id": "EV-PDB-1NVV-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.18}, "provenance": {"deposit_id": "1NVV", "doi": "10.1016/S0092-8674(03)00149-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NVV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NVW", "evidence_id": "EV-PDB-1NVW-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1NVW", "doi": "10.1016/S0092-8674(03)00149-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NVW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NVX", "evidence_id": "EV-PDB-1NVX-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "1NVX", "doi": "10.1016/S0092-8674(03)00149-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1P2T", "evidence_id": "EV-PDB-1P2T-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1P2T", "doi": "10.1016/S0969-2126(03)00128-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1P2T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras 166 in Aqueous mother liqour, RT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "IPA", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1P2U", "evidence_id": "EV-PDB-1P2U-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1P2U", "doi": "10.1016/S0969-2126(03)00128-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1P2U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras in 50% isopropanol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PLL", "evidence_id": "EV-PDB-1PLL-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1PLL", "doi": "10.1107/S090744499301443X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PLL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN CATALYTIC DOMAIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Q21", "evidence_id": "EV-PDB-1Q21-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1Q21", "doi": "10.1016/0022-2836(91)90753-S", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Q21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DBG", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "TRANSFORMING PROTEIN P21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RVD", "evidence_id": "EV-PDB-1RVD-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1RVD", "doi": "10.1073/pnas.96.12.7065", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RVD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AF3", "GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "H-RAS (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WQ1", "evidence_id": "EV-PDB-1WQ1-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1WQ1", "doi": "10.1126/science.277.5324.333", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WQ1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RAS-RASGAP COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-Ras-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1XD2", "evidence_id": "EV-PDB-1XD2-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1XD2", "doi": "10.1016/j.cell.2004.10.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1XD2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of a ternary Ras:SOS:Ras*GDP complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-Ras-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1XD2", "evidence_id": "EV-PDB-1XD2-2", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1XD2", "doi": "10.1016/j.cell.2004.10.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1XD2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of a ternary Ras:SOS:Ras*GDP complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-Ras-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1XJ0", "evidence_id": "EV-PDB-1XJ0-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1XJ0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1XJ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the GDP-bound form of the RasG60A mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-Ras-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZW6", "evidence_id": "EV-PDB-1ZW6-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1ZW6", "doi": "10.1016/j.str.2005.12.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZW6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the GTP-bound form of RasQ61G"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/221P", "evidence_id": "EV-PDB-221P-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "221P", "doi": "10.1016/0092-8674(90)90018-A", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/221P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2C5L", "evidence_id": "EV-PDB-2C5L-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2C5L", "doi": "10.1016/J.MOLCEL.2006.01.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2C5L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of PLC epsilon Ras association domain with hRas"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG", "XY2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CE2", "evidence_id": "EV-PDB-2CE2-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.0}, "provenance": {"deposit_id": "2CE2", "doi": "10.1529/BIOPHYSJ.105.078931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CE2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "TRS", "XY2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CL0", "evidence_id": "EV-PDB-2CL0-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2CL0", "doi": "10.1529/BIOPHYSJ.105.078931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CL0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAG", "MG", "XY2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CL6", "evidence_id": "EV-PDB-2CL6-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.24}, "provenance": {"deposit_id": "2CL6", "doi": "10.1529/BIOPHYSJ.105.078931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CL6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH S-caged GTP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "XY2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CL7", "evidence_id": "EV-PDB-2CL7-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.25}, "provenance": {"deposit_id": "2CL7", "doi": "10.1529/BIOPHYSJ.105.078931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CL7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GTP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "XY2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CLC", "evidence_id": "EV-PDB-2CLC-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "2CLC", "doi": "10.1529/BIOPHYSJ.105.078931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CLC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GTP (2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas, N-terminally processed (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/24SQ", "evidence_id": "EV-PDB-24SQ-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.08}, "provenance": {"deposit_id": "24SQ", "doi": "10.1021/jacs.6c14212", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/24SQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human HRAS WT (GDP-bound) in complex with macrocyclic peptide inhibitor AP6296"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-Ras-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZVQ", "evidence_id": "EV-PDB-1ZVQ-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1ZVQ", "doi": "10.1016/j.str.2005.12.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Q61G mutant of Ras in the GDP-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-Ras-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1XCM", "evidence_id": "EV-PDB-1XCM-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "1XCM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1XCM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the GppNHp-bound H-Ras G60A mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TRANSFORMING PROTEIN P21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QRA", "evidence_id": "EV-PDB-1QRA-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1QRA", "doi": "10.1016/S0969-2126(00)80021-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QRA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF P21RAS IN COMPLEX WITH GTP AT 100 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PLK", "evidence_id": "EV-PDB-1PLK-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1PLK", "doi": "10.1107/S090744499301443X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PLK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAG", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PLJ", "evidence_id": "EV-PDB-1PLJ-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1PLJ", "doi": "10.1107/S090744499301443X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PLJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "HEZ", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1P2V", "evidence_id": "EV-PDB-1P2V-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1P2V", "doi": "10.1016/S0969-2126(03)00128-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1P2V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RAS 166 in 60 % 1,6 hexanediol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ETF", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1P2S", "evidence_id": "EV-PDB-1P2S-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "1P2S", "doi": "10.1016/S0969-2126(03)00128-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1P2S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras 166 in 50% 2,2,2 triflouroethanol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Transforming protein p21/H-RAS-1 (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NVU", "evidence_id": "EV-PDB-1NVU-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1NVU", "doi": "10.1016/S0092-8674(03)00149-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NVU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AGN", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1GNP", "evidence_id": "EV-PDB-1GNP-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1GNP", "doi": "10.1006/jmbi.1995.0541", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1GNP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DBG", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "TRANSFORMING PROTEIN P21/H-RAS-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CLU", "evidence_id": "EV-PDB-1CLU-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1CLU", "doi": "10.1073/pnas.96.12.7065", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CLU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AGP", "evidence_id": "EV-PDB-1AGP-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1AGP", "doi": "10.1021/bi00084a005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AGP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLY-12 MUTANT OF P21-H-RAS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "C-HA-RAS (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AA9", "evidence_id": "EV-PDB-1AA9-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1AA9", "doi": "10.1021/bi970296u", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AA9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "HUMAN C-HA-RAS(1-171)(DOT)GDP, NMR, MINIMIZED AVERAGE STRUCTURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAG", "MG", "XY2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EVW", "evidence_id": "EV-PDB-2EVW-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.05}, "provenance": {"deposit_id": "2EVW", "doi": "10.1529/biophysj.105.078931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EVW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure analysis of a fluorescent form of H-Ras p21 in complex with R-caged GTP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LCF", "evidence_id": "EV-PDB-2LCF-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LCF", "doi": "10.1074/jbc.M111.227074", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LCF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of GppNHp-bound H-RasT35S mutant protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "KOB", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LWI", "evidence_id": "EV-PDB-2LWI-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LWI", "doi": "10.1073/pnas.1217730110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LWI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of H-RasT35S mutant protein in complex with Kobe2601"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N42", "evidence_id": "EV-PDB-2N42-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N42", "doi": "10.1038/nmeth.3455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N42"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "EC-NMR Structure of Human H-RasT35S mutant protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N46", "evidence_id": "EV-PDB-2N46-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N46", "doi": "10.1038/nmeth.3455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N46"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "EC-NMR Structure of Human H-RasT35S mutant protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN CATALYTIC DOMAIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Q21", "evidence_id": "EV-PDB-2Q21-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "2Q21", "doi": "10.1016/0022-2836(91)90753-S", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Q21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2QUZ", "evidence_id": "EV-PDB-2QUZ-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.49}, "provenance": {"deposit_id": "2QUZ", "doi": "10.1002/humu.20616", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2QUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the activating H-RasK117R mutant in Costello Syndrome, bound to Mg-GDP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RGA", "evidence_id": "EV-PDB-2RGA-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2RGA", "doi": "10.1016/j.str.2007.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RGA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-RasQ61I-GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RGB", "evidence_id": "EV-PDB-2RGB-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "2RGB", "doi": "10.1016/j.str.2007.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RGB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-RasQ61K-GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RGC", "evidence_id": "EV-PDB-2RGC-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "2RGC", "doi": "10.1016/j.str.2007.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RGC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-RasQ61V-GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RGD", "evidence_id": "EV-PDB-2RGD-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2RGD", "doi": "10.1016/j.str.2007.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RGD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-RasQ61L-GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RGE", "evidence_id": "EV-PDB-2RGE-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "2RGE", "doi": "10.1016/j.str.2007.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RGE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-Ras-GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RGG", "evidence_id": "EV-PDB-2RGG-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "2RGG", "doi": "10.1016/j.str.2007.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RGG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-RasQ61I-GppNHp, trigonal crystal form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2UZI", "evidence_id": "EV-PDB-2UZI-3", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2UZI", "doi": "10.1038/SJ.EMBOJ.7601744", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2UZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HRAS(G12V) - anti-RAS Fv complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2VH5", "evidence_id": "EV-PDB-2VH5-3", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "2VH5", "doi": "10.1016/J.JMB.2007.11.085", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2VH5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HRAS(G12V) - ANTI-RAS FV (disulfide free mutant) COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2X1V", "evidence_id": "EV-PDB-2X1V-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2X1V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2X1V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the activating H-Ras I163F mutant in Costello Syndrome, bound to MG-GDP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3DDC", "evidence_id": "EV-PDB-3DDC-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3DDC", "doi": "10.1038/emboj.2008.125", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3DDC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of NORE1A in Complex with RAS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3I3S", "evidence_id": "EV-PDB-3I3S-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.36}, "provenance": {"deposit_id": "3I3S", "doi": "10.1038/ng.497", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3I3S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of H-Ras with Thr50 replaced by Isoleucine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K8Y", "evidence_id": "EV-PDB-3K8Y-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "3K8Y", "doi": "10.1073/pnas.0912226107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K8Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Allosteric modulation of H-Ras GTPase"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K9N", "evidence_id": "EV-PDB-3K9N-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3K9N", "doi": "10.1073/pnas.0912226107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K9N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Allosteric modulation of H-Ras GTPase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KKN", "evidence_id": "EV-PDB-3KKN-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.09}, "provenance": {"deposit_id": "3KKN", "doi": "10.1074/jbc.M110.125161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KKN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-Ras T35S in complex with GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KUD", "evidence_id": "EV-PDB-3KUD-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "3KUD", "doi": "10.1016/j.jmb.2010.03.046", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KUD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex of Ras-GDP with RafRBD(A85K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG", "YCN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3L8Y", "evidence_id": "EV-PDB-3L8Y-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "3L8Y", "doi": "10.1002/anie.200907002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3L8Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex of Ras with cyclen"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3L8Z", "evidence_id": "EV-PDB-3L8Z-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.44}, "provenance": {"deposit_id": "3L8Z", "doi": "10.1002/anie.200907002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3L8Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras wildtype new crystal form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LBH", "evidence_id": "EV-PDB-3LBH-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "3LBH", "doi": "10.1073/pnas.0912226107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LBH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ras soaked in Calcium Acetate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LBI", "evidence_id": "EV-PDB-3LBI-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.087}, "provenance": {"deposit_id": "3LBI", "doi": "10.1073/pnas.0912226107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LBI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ras soaked in Magnesium Acetate and back soaked in Calcium Acetate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LBN", "evidence_id": "EV-PDB-3LBN-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.862}, "provenance": {"deposit_id": "3LBN", "doi": "10.1073/pnas.0912226107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LBN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ras soaked in Magnesium Acetate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GDP", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LO5", "evidence_id": "EV-PDB-3LO5-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.568}, "provenance": {"deposit_id": "3LO5", "doi": "10.1021/bi9020742", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LO5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the dominant negative S17N mutant of Ras"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OIU", "evidence_id": "EV-PDB-3OIU-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.32}, "provenance": {"deposit_id": "3OIU", "doi": "10.1074/jbc.M110.193854", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OIU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RasQ61L with allosteric switch in the \"on\" state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DTT", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OIV", "evidence_id": "EV-PDB-3OIV-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.837}, "provenance": {"deposit_id": "3OIV", "doi": "10.1074/jbc.M110.193854", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OIV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RasG12V with allosteric switch in the \"off\" state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OIW", "evidence_id": "EV-PDB-3OIW-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "3OIW", "doi": "10.1074/jbc.M110.193854", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OIW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-RasG12V with allosteric switch in the \"on\" state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RRY", "evidence_id": "EV-PDB-3RRY-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3RRY", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RRY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras crosslinked control, soaked in aqueous solution: one of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "GOL", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RRZ", "evidence_id": "EV-PDB-3RRZ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3RRZ", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RRZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras in 70% glycerol: one of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG", "YEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RS0", "evidence_id": "EV-PDB-3RS0-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "3RS0", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RS0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in neat cyclopentanol: one of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ETF", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RS2", "evidence_id": "EV-PDB-3RS2-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.836}, "provenance": {"deposit_id": "3RS2", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RS2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in 50% 2,2,2-trifluoroethanol: one of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "HEZ", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RS4", "evidence_id": "EV-PDB-3RS4-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3RS4", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RS4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in 60% 1,6-hexanediol: 1 of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DMF", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RS5", "evidence_id": "EV-PDB-3RS5-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.68}, "provenance": {"deposit_id": "3RS5", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RS5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in 55% dimethylformamide: 1 of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RS7", "evidence_id": "EV-PDB-3RS7-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3RS7", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RS7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in 50% isopropanol: 1 of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG", "RSF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RSL", "evidence_id": "EV-PDB-3RSL-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3RSL", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RSL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in 90% R,S,R-bisfuranol: one of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG", "RSG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RSO", "evidence_id": "EV-PDB-3RSO-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3RSO", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RSO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in 20% S,R,S-bisfuranol: 1 of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TGP", "evidence_id": "EV-PDB-3TGP-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3075}, "provenance": {"deposit_id": "3TGP", "doi": "10.1073/pnas.1111325108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TGP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature H-ras"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/421P", "evidence_id": "EV-PDB-421P-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "421P", "doi": "10.1016/0092-8674(90)90018-A", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/421P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DTU", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DLR", "evidence_id": "EV-PDB-4DLR-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.319}, "provenance": {"deposit_id": "4DLR", "doi": "10.1021/bi300509j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DLR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras PEG 400/Ca(OAc)2, ordered off"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DLS", "evidence_id": "EV-PDB-4DLS-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.819}, "provenance": {"deposit_id": "4DLS", "doi": "10.1021/bi300509j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DLS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras Set 1 CaCl2 'Mixed'"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DLT", "evidence_id": "EV-PDB-4DLT-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.699}, "provenance": {"deposit_id": "4DLT", "doi": "10.1021/bi300509j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DLT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras Set 2 Ca(OAc)2, on"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DLU", "evidence_id": "EV-PDB-4DLU-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "4DLU", "doi": "10.1021/bi300509j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DLU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras Set 1 Ca(OAc)2, on"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "HEX", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RS3", "evidence_id": "EV-PDB-3RS3-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.52}, "provenance": {"deposit_id": "3RS3", "doi": "10.1016/j.jmb.2011.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RS3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras soaked in neat hexane: 1 of 10 in MSCS set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KKM", "evidence_id": "EV-PDB-3KKM-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3KKM", "doi": "10.1074/jbc.M110.125161", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KKM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of H-Ras T35S in complex with GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CLD", "evidence_id": "EV-PDB-2CLD-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.22}, "provenance": {"deposit_id": "2CLD", "doi": "10.1529/BIOPHYSJ.105.078931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CLD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP (2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "DTU", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4G0N", "evidence_id": "EV-PDB-4G0N-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "4G0N", "doi": "10.1016/j.str.2014.12.017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4G0N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of wt H-Ras-GppNHp bound to the RBD of Raf Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4G3X", "evidence_id": "EV-PDB-4G3X-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "4G3X", "doi": "10.1016/j.str.2014.12.017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4G3X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Q61L H-Ras-GppNHp bound to the RBD of Raf Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GDP", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4L9S", "evidence_id": "EV-PDB-4L9S-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.606}, "provenance": {"deposit_id": "4L9S", "doi": "10.1038/nature12796", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4L9S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of H-Ras G12C, GDP-bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2PZ", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NYJ", "evidence_id": "EV-PDB-4NYJ-2", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8522}, "provenance": {"deposit_id": "4NYJ", "doi": "10.1073/pnas.1315798111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2PZ", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NYJ", "evidence_id": "EV-PDB-4NYJ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8522}, "provenance": {"deposit_id": "4NYJ", "doi": "10.1073/pnas.1315798111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RV1"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4URY", "evidence_id": "EV-PDB-4URY-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.47}, "provenance": {"deposit_id": "4URY", "doi": "10.1021/JM501660T", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4URY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of H-Ras and SOS in complex with ligands"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5P21", "evidence_id": "EV-PDB-5P21-1", "mappings": [{"confidence": "high", "justification": "GppNHp (GNP) bound, triphosphate conformation.", "rule": "curator_assignment", "state_id": "Ras-GTP", "who": "curator:draft (unreviewed)"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "5P21", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5P21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "REFINED CRYSTAL STRUCTURE OF THE TRIPHOSPHATE CONFORMATION OF H-RAS P21 AT 1.35 ANGSTROMS RESOLUTION: IMPLICATIONS FOR THE MECHANISM OF GTP HYDROLYSIS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["92V", "GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VBE", "evidence_id": "EV-PDB-5VBE-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.57}, "provenance": {"deposit_id": "5VBE", "doi": "10.1016/j.chembiol.2017.08.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VBE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GDP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,D,G,J)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WPL", "evidence_id": "EV-PDB-5WPL-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "5WPL", "doi": "10.1074/jbc.M117.816348", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WPL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KRas G12V, bound to GppNHp and miniprotein 225-11"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EC4", "FMT", "GNP", "GOL", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BVI", "evidence_id": "EV-PDB-6BVI-3", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.746}, "provenance": {"deposit_id": "6BVI", "doi": "10.1021/acs.jmedchem.8b00360", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BVI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ras:SOS:Ras in complex with a small molecule activator"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EC4", "FMT", "GNP", "GOL", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BVI", "evidence_id": "EV-PDB-6BVI-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.746}, "provenance": {"deposit_id": "6BVI", "doi": "10.1021/acs.jmedchem.8b00360", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BVI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ras:SOS:Ras in complex with a small molecule activator"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains B,D,F,H,J,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6AXG", "evidence_id": "EV-PDB-6AXG-2", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.302}, "provenance": {"deposit_id": "6AXG", "doi": "10.7554/eLife.29002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6AXG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of RasGRP4 in complex with HRas"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6AMB", "evidence_id": "EV-PDB-6AMB-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6AMB", "doi": "10.1038/s41467-017-01326-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6AMB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the Afadin RA1 domain in complex with HRAS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/621P", "evidence_id": "EV-PDB-621P-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "621P", "doi": "10.1016/0092-8674(90)90018-A", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/621P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "KBF", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ZC6", "evidence_id": "EV-PDB-5ZC6-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "5ZC6", "doi": "10.1021/acs.biochem.8b00680", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ZC6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of H-RasT35S mutant protein in complex with KBFM123"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5X9S", "evidence_id": "EV-PDB-5X9S-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "5X9S", "doi": "10.1002/1873-3468.12759", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5X9S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of fully modified H-Ras-GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["5UW", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WFR", "evidence_id": "EV-PDB-5WFR-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.46}, "provenance": {"deposit_id": "5WFR", "doi": "10.1016/j.ab.2018.01.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WFR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ligand-bound Ras:SOS:Ras complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["5UV", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WFQ", "evidence_id": "EV-PDB-5WFQ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26}, "provenance": {"deposit_id": "5WFQ", "doi": "10.1016/j.ab.2018.01.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WFQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ligand-bound Ras:SOS:Ras complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["5UX", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WFP", "evidence_id": "EV-PDB-5WFP-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.08}, "provenance": {"deposit_id": "5WFP", "doi": "10.1016/j.ab.2018.01.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WFP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ligand-bound Ras:SOS:Ras complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["5UU", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WFO", "evidence_id": "EV-PDB-5WFO-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "5WFO", "doi": "10.1016/j.ab.2018.01.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WFO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ligand-bound Ras:SOS:Ras complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "GNP", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WDQ", "evidence_id": "EV-PDB-5WDQ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.25}, "provenance": {"deposit_id": "5WDQ", "doi": "10.7554/eLife.27810", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WDQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras mutant L120A bound to GMP-PNP at 100K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WDP", "evidence_id": "EV-PDB-5WDP-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "5WDP", "doi": "10.7554/eLife.27810", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WDP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras mutant L120A bound to GMP-PNP at 277K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WDO", "evidence_id": "EV-PDB-5WDO-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "5WDO", "doi": "10.7554/eLife.27810", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WDO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras bound to GMP-PNP at 277K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["92V", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VBZ", "evidence_id": "EV-PDB-5VBZ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "5VBZ", "doi": "10.1016/j.chembiol.2017.08.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VBZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5E95", "evidence_id": "EV-PDB-5E95-2", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.402}, "provenance": {"deposit_id": "5E95", "doi": "10.1038/nchembio.2231", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5E95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Mb(NS1)/H-Ras Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B30", "evidence_id": "EV-PDB-5B30-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "5B30", "doi": "10.1038/srep25931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B30"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras WT in complex with GppNHp (state 1) after structural transition by humidity control"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B2Z", "evidence_id": "EV-PDB-5B2Z-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.56}, "provenance": {"deposit_id": "5B2Z", "doi": "10.1038/srep25931", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B2Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras WT in complex with GppNHp (state 2*) before structural transition by humidity control"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/521P", "evidence_id": "EV-PDB-521P-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "521P", "doi": "10.1016/0092-8674(90)90018-A", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/521P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XVR", "evidence_id": "EV-PDB-4XVR-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.031}, "provenance": {"deposit_id": "4XVR", "doi": "10.1096/fj.15-271510", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XVR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras Y137F"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "GOL", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XVQ", "evidence_id": "EV-PDB-4XVQ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.887}, "provenance": {"deposit_id": "4XVQ", "doi": "10.1096/fj.15-271510", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras Y137E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["L7S"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4US2", "evidence_id": "EV-PDB-4US2-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.48}, "provenance": {"deposit_id": "4US2", "doi": "10.1021/JM501660T", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4US2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of H-Ras and SOS in complex with ligands"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["L71"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPASE HRAS (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4US1", "evidence_id": "EV-PDB-4US1-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "4US1", "doi": "10.1021/JM501660T", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4US1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of H-Ras and SOS in complex with ligands"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "RND"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NYM", "evidence_id": "EV-PDB-4NYM-2", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5529}, "provenance": {"deposit_id": "4NYM", "doi": "10.1073/pnas.1315798111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "RND"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NYM", "evidence_id": "EV-PDB-4NYM-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5529}, "provenance": {"deposit_id": "4NYM", "doi": "10.1073/pnas.1315798111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2PX", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NYI", "evidence_id": "EV-PDB-4NYI-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9612}, "provenance": {"deposit_id": "4NYI", "doi": "10.1073/pnas.1315798111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NYI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -100.0}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6E6C", "evidence_id": "EV-PDB-6E6C-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "6E6C", "doi": "10.1016/j.celrep.2019.07.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6E6C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS G13D bound to GppNHp (H13GNP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MQT", "evidence_id": "EV-PDB-6MQT-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.498}, "provenance": {"deposit_id": "6MQT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MQT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS G12S in complex with GDP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "GOL", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6NTC", "evidence_id": "EV-PDB-6NTC-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6NTC", "doi": "10.1074/jbc.RA119.011025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6NTC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of G12V HRas-GppNHp bound in complex with the engineered RBD variant 1 of CRAF Kinase protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6NTD", "evidence_id": "EV-PDB-6NTD-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15}, "provenance": {"deposit_id": "6NTD", "doi": "10.1074/jbc.RA119.011025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6NTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of G12V HRas-GppNHp bound in complex with the engineered RBD variant 12 of CRAF Kinase protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GCP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN CATALYTIC DOMAIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Q21", "evidence_id": "EV-PDB-6Q21-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "6Q21", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Q21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MOLECULAR SWITCH FOR SIGNAL TRANSDUCTION: STRUCTURAL DIFFERENCES BETWEEN ACTIVE AND INACTIVE FORMS OF PROTOONCOGENIC RAS PROTEINS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/721P", "evidence_id": "EV-PDB-721P-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "721P", "doi": "10.1016/0092-8674(90)90018-A", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/721P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DPH", "evidence_id": "EV-PDB-7DPH-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.54}, "provenance": {"deposit_id": "7DPH", "doi": "10.1016/j.bbrc.2021.05.084", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DPH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H-Ras Q61H in complex with GppNHp (state 1) after structural transition by humidity control"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "GOL", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -100.0}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JIF", "evidence_id": "EV-PDB-7JIF-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.757}, "provenance": {"deposit_id": "7JIF", "doi": "10.1016/j.molcel.2022.02.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JIF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS A59T GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -100.0}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JIG", "evidence_id": "EV-PDB-7JIG-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.322}, "provenance": {"deposit_id": "7JIG", "doi": "10.1016/j.molcel.2022.02.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JIG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS A59T GppNHp crystal 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -100.0}, "construct": {"description": "GTPase HRas (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JII", "evidence_id": "EV-PDB-7JII-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.532}, "provenance": {"deposit_id": "7JII", "doi": "10.1016/j.molcel.2022.02.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JII"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS A59E GDP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GSP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,E,G,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L0F", "evidence_id": "EV-PDB-7L0F-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.98}, "provenance": {"deposit_id": "7L0F", "doi": "10.1038/s41467-021-22969-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Monobody 12VC3 Bound to HRAS(WT)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GSP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,E,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L0G", "evidence_id": "EV-PDB-7L0G-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.54}, "provenance": {"deposit_id": "7L0G", "doi": "10.1038/s41467-021-22969-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L0G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Monobody 12VC1 Bound to HRAS(G12C)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OG9", "evidence_id": "EV-PDB-7OG9-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "7OG9", "doi": "10.1039/d1sc05488k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OG9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPase HRAS under ambient pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OGA", "evidence_id": "EV-PDB-7OGA-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "7OGA", "doi": "10.1039/d1sc05488k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OGA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPase HRAS under 200 MPa pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OGB", "evidence_id": "EV-PDB-7OGB-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "7OGB", "doi": "10.1039/d1sc05488k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OGB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPase HRAS under 500 MPa pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OGC", "evidence_id": "EV-PDB-7OGC-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "7OGC", "doi": "10.1039/d1sc05488k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OGC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPase HRAS under 650 MPa pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OGD", "evidence_id": "EV-PDB-7OGD-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "7OGD", "doi": "10.1039/d1sc05488k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OGD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPase HRAS mutant D33K under ambient pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OGE", "evidence_id": "EV-PDB-7OGE-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "7OGE", "doi": "10.1039/d1sc05488k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OGE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPase HRAS mutant D33K under 200 MPa pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "GOL", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -100.0}, "construct": {"description": "GTPase HRas (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JIH", "evidence_id": "EV-PDB-7JIH-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.989}, "provenance": {"deposit_id": "7JIH", "doi": "10.1016/j.molcel.2022.02.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JIH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS A59E GppNHp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JHP", "evidence_id": "EV-PDB-7JHP-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.766}, "provenance": {"deposit_id": "7JHP", "doi": "10.3390/biom11070996", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JHP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HRas in complex with the Ras-binding and cysteine-rich domains of CRaf-kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT", "GNP", "GOL", "MG", "NA", "QTG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6V9M", "evidence_id": "EV-PDB-6V9M-3", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.648}, "provenance": {"deposit_id": "6V9M", "doi": "10.1021/acs.jmedchem.0c00511", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6V9M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT", "GNP", "GOL", "MG", "NA", "QTG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6V9M", "evidence_id": "EV-PDB-6V9M-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.648}, "provenance": {"deposit_id": "6V9M", "doi": "10.1021/acs.jmedchem.0c00511", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6V9M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "GOL", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6E6P", "evidence_id": "EV-PDB-6E6P-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.93}, "provenance": {"deposit_id": "6E6P", "doi": "10.1016/j.celrep.2019.07.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6E6P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS G13D bound to GppNHp (Ha,b,c13GNP)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVE", "evidence_id": "EV-PDB-9PVE-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9PVE", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0152533 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WRU", "evidence_id": "EV-PDB-9WRU-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "9WRU", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WRU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SS-ROX structure analysis of H-Ras using caged-compound complex: freeze-trap series (5 hr after UV light irradiation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WRT", "evidence_id": "EV-PDB-9WRT-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "9WRT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WRT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SS-ROX structure analysis of H-Ras using caged-compound complex: freeze-trap series (2.5 h after UV light irradiation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WRS", "evidence_id": "EV-PDB-9WRS-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "9WRS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WRS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SS-ROX structure analysis of H-Ras using caged-compound complex: freeze-trap series (within 15 min after UV light irradiation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WRR", "evidence_id": "EV-PDB-9WRR-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "9WRR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WRR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SS-ROX structure analysis of H-Ras using caged-compound complex: 28 hr after UV light irradiation (GDP bound form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GTP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WRQ", "evidence_id": "EV-PDB-9WRQ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9WRQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WRQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SS-ROX structure analysis of H-Ras using caged-compound complex: 15 min after UV light irradiation (GTP bound form state 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CAG", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WRP", "evidence_id": "EV-PDB-9WRP-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "9WRP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WRP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SS-ROX structure analysis of H-Ras using caged-compound complex: before UV light irradiation (NPE-caged GTP bound)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PUT", "evidence_id": "EV-PDB-9PUT-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9PUT", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PUT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0152535 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PUQ", "evidence_id": "EV-PDB-9PUQ-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9PUQ", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PUQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0152248 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PUN", "evidence_id": "EV-PDB-9PUN-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "9PUN", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PUN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0148697 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PUL", "evidence_id": "EV-PDB-9PUL-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "9PUL", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PUL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0143525 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PU8", "evidence_id": "EV-PDB-9PU8-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "9PU8", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PU8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0140693 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PU3", "evidence_id": "EV-PDB-9PU3-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "9PU3", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PU3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0140692 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PU1", "evidence_id": "EV-PDB-9PU1-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "9PU1", "doi": "10.1021/acsmedchemlett.6c00078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PU1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS complex with UM0140401 compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1CG4", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9P46", "evidence_id": "EV-PDB-9P46-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "9P46", "doi": "10.1158/2159-8290.CD-25-1280", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9P46"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HRAS-G12D/Q95H (GMPPNP-bound) in complex with BBO-11818"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WWC", "evidence_id": "EV-PDB-8WWC-2", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8WWC", "doi": "10.1038/s41592-024-02437-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WWC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "De novo design binder of HRAS -120-4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG", "MOV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -195.79}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TLR", "evidence_id": "EV-PDB-8TLR-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.70003947485}, "provenance": {"deposit_id": "8TLR", "doi": "10.1016/j.cell.2024.08.017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TLR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of human HRAS G12C covalently bound to AMG 510"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PGE", "YCN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OSO", "evidence_id": "EV-PDB-8OSO-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8OSO", "doi": "10.1002/chem.202400304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OSO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPase HRAS in complex with Zn-cyclen under 500 MPa pressure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OSN", "evidence_id": "EV-PDB-8OSN-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "8OSN", "doi": "10.1002/chem.202400304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OSN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPASE HRAS IN COMPLEX WITH ZN-CYCLEN AT AMBIENT PRESSURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OSM", "evidence_id": "EV-PDB-8OSM-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "8OSM", "doi": "10.1002/chem.202400304", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OSM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GTPASE HRAS IN COMPLEX WITH ZN-CYCLEN AT 200 MPA PRESSURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FG4", "evidence_id": "EV-PDB-8FG4-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "8FG4", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FG4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97L Crystal Form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EM0", "evidence_id": "EV-PDB-8EM0-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.109}, "provenance": {"deposit_id": "8EM0", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97V Crystal Form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DTT", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELZ", "evidence_id": "EV-PDB-8ELZ-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.961}, "provenance": {"deposit_id": "8ELZ", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97M Crystal Form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELY", "evidence_id": "EV-PDB-8ELY-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "8ELY", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97M Crystal Form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELX", "evidence_id": "EV-PDB-8ELX-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.975}, "provenance": {"deposit_id": "8ELX", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97I Crystal Form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELW", "evidence_id": "EV-PDB-8ELW-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.699}, "provenance": {"deposit_id": "8ELW", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97A Crystal Form 1 T-State"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELV", "evidence_id": "EV-PDB-8ELV-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.153}, "provenance": {"deposit_id": "8ELV", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97I Crystal Form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELU", "evidence_id": "EV-PDB-8ELU-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.93}, "provenance": {"deposit_id": "8ELU", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97G Crystal form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELT", "evidence_id": "EV-PDB-8ELT-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.66}, "provenance": {"deposit_id": "8ELT", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97G Crystal Form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELS", "evidence_id": "EV-PDB-8ELS-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.267}, "provenance": {"deposit_id": "8ELS", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97A Crystal Form 1 R-state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELR", "evidence_id": "EV-PDB-8ELR-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "8ELR", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97F Crystal Form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GNP", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELK", "evidence_id": "EV-PDB-8ELK-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "8ELK", "doi": "10.1002/pro.4767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRAS R97F Crystal Form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "BEF", "GDP", "MG", "PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CNN", "evidence_id": "EV-PDB-8CNN-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "8CNN", "doi": "10.1038/s42004-024-01105-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CNN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BeF3 Phospho-HRas GSA complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GDP", "MG", "MPD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CNJ", "evidence_id": "EV-PDB-8CNJ-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "8CNJ", "doi": "10.1038/s42004-024-01105-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CNJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRas(1-166) in complex with GDP and BeF3-"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDP", "MG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BWG", "evidence_id": "EV-PDB-8BWG-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.32}, "provenance": {"deposit_id": "8BWG", "doi": "10.1038/s42004-024-01105-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BWG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRas (1-166) Y64 phosphorylation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GAI", "GDP", "MG", "MGF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BOS", "evidence_id": "EV-PDB-8BOS-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8BOS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BOS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Transition state analogue complex of small G protein and its GAP effector"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BEA", "evidence_id": "EV-PDB-8BEA-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.47}, "provenance": {"deposit_id": "8BEA", "doi": "10.1002/anie.202219095", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SOS1-HRas-peptidomimetic10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "FMT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BE9", "evidence_id": "EV-PDB-8BE9-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "8BE9", "doi": "10.1002/anie.202219095", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BE9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SOS1-HRas-peptidomimetic5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BE8", "evidence_id": "EV-PDB-8BE8-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "8BE8", "doi": "10.1002/anie.202219095", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SOS1-HRas-peptidomimetic4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BE7", "evidence_id": "EV-PDB-8BE7-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8BE7", "doi": "10.1002/anie.202219095", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SOS1-HRas-peptidomimetic3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BE6", "evidence_id": "EV-PDB-8BE6-1", "mappings": [], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89880249261}, "provenance": {"deposit_id": "8BE6", "doi": "10.1002/anie.202219095", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BE6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SOS1-HRas-peptidomimetic2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "C-H-RAS P21 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/821P", "evidence_id": "EV-PDB-821P-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "821P", "doi": "10.1021/bi00084a005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/821P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLYCINE-12 MUTANT OF P21H-RAS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VVG", "evidence_id": "EV-PDB-7VVG-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "7VVG", "doi": "10.1073/pnas.2119990119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VVG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HRasG12V(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VV9", "evidence_id": "EV-PDB-7VV9-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "7VV9", "doi": "10.1073/pnas.2119990119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VV9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HRas(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VV8", "evidence_id": "EV-PDB-7VV8-1", "mappings": [{"confidence": "high", "justification": "GTP or a non-hydrolysable analogue (GNP, GCP, GSP) bound.", "rule": "ras-gtp-analogue", "state_id": "Ras-GTP", "who": "rule:ras-gtp-analogue"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "7VV8", "doi": "10.1073/pnas.2119990119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VV8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HRasQ61L(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GDP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GTPase HRas (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TAM", "evidence_id": "EV-PDB-7TAM-1", "mappings": [{"confidence": "high", "justification": "GDP bound and no GTP analogue present.", "rule": "ras-gdp", "state_id": "Ras-GDP", "who": "rule:ras-gdp"}], "molecule_id": "P01112", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.87}, "provenance": {"deposit_id": "7TAM", "doi": "10.1021/acsomega.4c10493", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TAM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HRas G12V in complex with GDP"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17678", "evidence_id": "EV-BMRB-17678", "mappings": [], "molecule_id": "P01112", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17678", "doi": "10.13018/BMR17678", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17678"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "HRas166*GppNHp backbone chemical shift assignments"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts, heteronuclear NOE values, T1 relaxation values, T2 relaxation values", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=18461", "evidence_id": "EV-BMRB-18461", "mappings": [], "molecule_id": "P01112", "observable": {"type": "relaxation_rate", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr18461", "doi": "10.13018/BMR18461", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=18461"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_dynamics", "title": "Chemical shift assignments and backbone dynamics of H-Ras-GppNHp bound to Ras-binding domain of cRaf1."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=18629", "evidence_id": "EV-BMRB-18629", "mappings": [], "molecule_id": "P01112", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr18629", "doi": "10.13018/BMR18629", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=18629"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of H-RasT35S mutant protein in complex with Kobe2601"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/102M", "evidence_id": "EV-PDB-102M-1", "mappings": [{"confidence": "medium", "justification": "Title says aquomet or metmyoglobin.", "rule": "mb-met-title", "state_id": "Mb-aquomet", "who": "rule:mb-met-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "102M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/102M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN H64A AQUOMET AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/103M", "evidence_id": "EV-PDB-103M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.07}, "provenance": {"deposit_id": "103M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/103M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN H64A N-BUTYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/104M", "evidence_id": "EV-PDB-104M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.71}, "provenance": {"deposit_id": "104M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/104M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN N-BUTYL ISOCYANIDE AT PH 7.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/105M", "evidence_id": "EV-PDB-105M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "105M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/105M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN N-BUTYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ENC", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/106M", "evidence_id": "EV-PDB-106M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "106M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/106M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN V68F ETHYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/107M", "evidence_id": "EV-PDB-107M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.09}, "provenance": {"deposit_id": "107M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/107M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN V68F N-BUTYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/108M", "evidence_id": "EV-PDB-108M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67}, "provenance": {"deposit_id": "108M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/108M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN V68F N-BUTYL ISOCYANIDE AT PH 7.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ENC", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/109M", "evidence_id": "EV-PDB-109M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "109M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/109M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN D122N ETHYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "MNC", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/110M", "evidence_id": "EV-PDB-110M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.77}, "provenance": {"deposit_id": "110M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/110M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN D122N METHYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/111M", "evidence_id": "EV-PDB-111M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.88}, "provenance": {"deposit_id": "111M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/111M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN D122N N-BUTYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NPN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/112M", "evidence_id": "EV-PDB-112M-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.34}, "provenance": {"deposit_id": "112M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/112M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN D122N N-PROPYL ISOCYANIDE AT PH 9.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1A6G", "evidence_id": "EV-PDB-1A6G-1", "mappings": [{"confidence": "high", "justification": "Title: carbonmonoxy-myoglobin; CMO ligand present.", "rule": "curator_assignment", "state_id": "Mb-CO", "who": "curator:draft (unreviewed)"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "1A6G", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1A6G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CARBONMONOXY-MYOGLOBIN, ATOMIC RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1A6K", "evidence_id": "EV-PDB-1A6K-1", "mappings": [{"confidence": "high", "justification": "Title: aquomet-myoglobin.", "rule": "curator_assignment", "state_id": "Mb-aquomet", "who": "curator:draft (unreviewed)"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "1A6K", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1A6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "AQUOMET-MYOGLOBIN, ATOMIC RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OXY", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1A6M", "evidence_id": "EV-PDB-1A6M-1", "mappings": [{"confidence": "high", "justification": "Title: oxy-myoglobin; OXY ligand present.", "rule": "curator_assignment", "state_id": "Mb-oxy", "who": "curator:draft (unreviewed)"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.0}, "provenance": {"deposit_id": "1A6M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1A6M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "OXY-MYOGLOBIN, ATOMIC RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1A6N", "evidence_id": "EV-PDB-1A6N-1", "mappings": [{"confidence": "high", "justification": "Title: deoxy-myoglobin, atomic resolution.", "rule": "curator_assignment", "state_id": "Mb-deoxy", "who": "curator:draft (unreviewed)"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "1A6N", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1A6N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DEOXY-MYOGLOBIN, ATOMIC RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -253.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ABS", "evidence_id": "EV-PDB-1ABS-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1ABS", "doi": "10.1038/371808a0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ABS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PHOTOLYSED CARBONMONOXY-MYOGLOBIN AT 20 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -233.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AJG", "evidence_id": "EV-PDB-1AJG-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "1AJG", "doi": "10.1038/nsb1094-701", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AJG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CARBONMONOXY MYOGLOBIN AT 40 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -233.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AJH", "evidence_id": "EV-PDB-1AJH-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "1AJH", "doi": "10.1038/nsb1094-701", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AJH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PHOTOPRODUCT OF CARBONMONOXY MYOGLOBIN AT 40 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "APOMYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BVC", "evidence_id": "EV-PDB-1BVC-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1BVC", "doi": "10.1006/jmbi.1994.0142", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BVC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF A BILIVERDIN APOMYOGLOBIN COMPLEX (FORM D) AT 118 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "APOMYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BVD", "evidence_id": "EV-PDB-1BVD-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1BVD", "doi": "10.1006/jmbi.1994.0142", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BVD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF A BILIVERDIN APOMYOGLOBIN COMPLEX (FORM B) AT 98 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BZ6", "evidence_id": "EV-PDB-1BZ6-1", "mappings": [{"confidence": "medium", "justification": "Title says aquomet or metmyoglobin.", "rule": "mb-met-title", "state_id": "Mb-aquomet", "who": "rule:mb-met-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.2}, "provenance": {"deposit_id": "1BZ6", "doi": "10.1126/science.284.5413.473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BZ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ATOMIC RESOLUTION CRYSTAL STRUCTURE AQUOMET-MYOGLOBIN FROM SPERM WHALE AT ROOM TEMPERATURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.9, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BZP", "evidence_id": "EV-PDB-1BZP-1", "mappings": [{"confidence": "medium", "justification": "Title says deoxy and no CO, O2 or NO ligand is present.", "rule": "mb-deoxy-title", "state_id": "Mb-deoxy", "who": "rule:mb-deoxy-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "1BZP", "doi": "10.1126/science.284.5413.473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BZP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ATOMIC RESOLUTION CRYSTAL STRUCTURE ANALYSIS OF NATIVE DEOXY AND CO MYOGLOBIN FROM SPERM WHALE AT ROOM TEMPERATURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.9, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BZR", "evidence_id": "EV-PDB-1BZR-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "1BZR", "doi": "10.1126/science.284.5413.473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BZR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ATOMIC RESOLUTION CRYSTAL STRUCTURE ANALYSIS OF NATIVE DEOXY AND CO MYOGLOBIN FROM SPERM WHALE AT ROOM TEMPERATURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CH1", "evidence_id": "EV-PDB-1CH1-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1CH1", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CH1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Recombinant sperm whale myoglobin L89G mutatnt (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CH2", "evidence_id": "EV-PDB-1CH2-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1CH2", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CH2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L89F MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CH7", "evidence_id": "EV-PDB-1CH7-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1CH7", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CH7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN H97F MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CH9", "evidence_id": "EV-PDB-1CH9-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1CH9", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CH9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN H97Q MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CIK", "evidence_id": "EV-PDB-1CIK-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1CIK", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CIK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN I99A MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CIO", "evidence_id": "EV-PDB-1CIO-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1CIO", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CIO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN I99V MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CO8", "evidence_id": "EV-PDB-1CO8-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1CO8", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CO8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L104A MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CO9", "evidence_id": "EV-PDB-1CO9-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1CO9", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L104V MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CP0", "evidence_id": "EV-PDB-1CP0-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1CP0", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CP0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L104N MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CP5", "evidence_id": "EV-PDB-1CP5-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1CP5", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CP5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L104F MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CPW", "evidence_id": "EV-PDB-1CPW-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1CPW", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CPW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L104W MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CQ2", "evidence_id": "EV-PDB-1CQ2-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1CQ2", "doi": "10.1073/pnas.060024697", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CQ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "neutron", "title": "NEUTRON STRUCTURE OF FULLY DEUTERATED SPERM WHALE MYOGLOBIN AT 2.0 ANGSTROM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4", "branched: alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DO1", "evidence_id": "EV-PDB-1DO1-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1DO1", "doi": "10.1038/35004622", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DO1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CARBONMONOXY-MYOGLOBIN MUTANT L29W AT 105K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4", "branched: alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DO3", "evidence_id": "EV-PDB-1DO3-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "1DO3", "doi": "10.1038/35004622", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DO3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CARBONMONOXY-MYOGLOBIN (MUTANT L29W) AFTER PHOTOLYSIS AT T>180K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4", "branched: alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DO4", "evidence_id": "EV-PDB-1DO4-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1DO4", "doi": "10.1038/35004622", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DO4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CARBONMONOXY-MYOGLOBIN (MUTANT L29W) AFTER PHOTOLYSIS AT T<180K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DTI", "evidence_id": "EV-PDB-1DTI-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1DTI", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Recombinant sperm whale myoglobin h97d, d122n mutant (met)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["4MZ", "HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "RECOMBINANT SPERM WHALE MYOGLOBIN VARIANT H93G (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DTM", "evidence_id": "EV-PDB-1DTM-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.13}, "provenance": {"deposit_id": "1DTM", "doi": "10.1002/(SICI)1097-0134(20000601)39:4<278::AID-PROT20>3.0.CO;2-T", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DTM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE SPERM-WHALE MYOGLOBIN MUTANT H93G COMPLEXED WITH 4-METHYLIMIDAZOLE, METAQUO FORM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "WILD-TYPE RECOMBINANT SPERM WHALE METAQUOMYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DUK", "evidence_id": "EV-PDB-1DUK-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.13}, "provenance": {"deposit_id": "1DUK", "doi": "10.1002/(SICI)1097-0134(20000601)39:4<278::AID-PROT20>3.0.CO;2-T", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DUK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "WILD-TYPE RECOMBINANT SPERM WHALE METAQUOMYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1MZ", "HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "SPERM WHALE METAQUOMYOGLOBIN VARIANT H93G (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DUO", "evidence_id": "EV-PDB-1DUO-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1DUO", "doi": "10.1002/(SICI)1097-0134(20000601)39:4<278::AID-PROT20>3.0.CO;2-T", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DUO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE METAQUOMYOGLOBIN PROXIMAL HISTIDINE MUTANT H93G WITH 1-METHYLIMIDAZOLE AS PROXIMAL LIGAND."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DXC", "evidence_id": "EV-PDB-1DXC-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1DXC", "doi": "10.1073/PNAS.040459697", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CO complex of Myoglobin Mb-YQR at 100K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CYN", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EBC", "evidence_id": "EV-PDB-1EBC-1", "mappings": [{"confidence": "medium", "justification": "Title says aquomet or metmyoglobin.", "rule": "mb-met-title", "state_id": "Mb-aquomet", "who": "rule:mb-met-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1EBC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EBC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MET-MYOGLOBIN:CYANIDE COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1F63", "evidence_id": "EV-PDB-1F63-1", "mappings": [{"confidence": "medium", "justification": "Title says deoxy and no CO, O2 or NO ligand is present.", "rule": "mb-deoxy-title", "state_id": "Mb-deoxy", "who": "rule:mb-deoxy-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1F63", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1F63"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF DEOXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -253.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DXD", "evidence_id": "EV-PDB-1DXD-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1DXD", "doi": "10.1073/PNAS.040459697", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO complex of Myoglobin Mb-YQR at 20K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4", "branched: alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DO7", "evidence_id": "EV-PDB-1DO7-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1DO7", "doi": "10.1038/35004622", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DO7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CARBONMONOXY-MYOGLOBIN (MUTANT L29W) REBINDING STRUCTURE AFTER PHOTOLYSIS AT T< 180K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CH5", "evidence_id": "EV-PDB-1CH5-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1CH5", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CH5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN H97V MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "PROTEIN (MYOGLOBIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CH3", "evidence_id": "EV-PDB-1CH3-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1CH3", "doi": "10.1074/jbc.M008593200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CH3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L89W MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OXY", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1F65", "evidence_id": "EV-PDB-1F65-1", "mappings": [{"confidence": "high", "justification": "O2 (ligand OXY) bound to the heme.", "rule": "mb-o2-ligand", "state_id": "Mb-oxy", "who": "rule:mb-o2-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1F65", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1F65"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF OXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CYN", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1H1X", "evidence_id": "EV-PDB-1H1X-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1H1X", "doi": "10.1042/BJ20030863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1H1X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Sperm whale Myoglobin mutant T67R S92D"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HJT", "evidence_id": "EV-PDB-1HJT-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1HJT", "doi": "10.1002/(SICI)1097-0134(19980301)30:4<352::AID-PROT2>3.3.CO;2-G", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HJT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN (FERROUS, NITRIC OXIDE BOUND)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CYN", "HE6", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IOP", "evidence_id": "EV-PDB-1IOP-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1IOP", "doi": "10.1021/bi972632c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IOP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "INCORPORATION OF A HEMIN WITH THE SHORTEST ACID SIDE-CHAINS INTO MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "IMD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (METAQUO) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IRC", "evidence_id": "EV-PDB-1IRC-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.17}, "provenance": {"deposit_id": "1IRC", "doi": "10.1021/bi00187a023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IRC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CYSTEINE RICH INTESTINAL PROTEIN"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OXY", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LTW", "evidence_id": "EV-PDB-1LTW-1", "mappings": [{"confidence": "high", "justification": "O2 (ligand OXY) bound to the heme.", "rule": "mb-o2-ligand", "state_id": "Mb-oxy", "who": "rule:mb-o2-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1LTW", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LTW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN 29W MUTANT (OXY)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LUE", "evidence_id": "EV-PDB-1LUE-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1LUE", "doi": "10.1021/bi034605u", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LUE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN H64D/V68A/D122N MUTANT (MET)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MBD", "evidence_id": "EV-PDB-1MBD-1", "mappings": [{"confidence": "medium", "justification": "Title says deoxy and no CO, O2 or NO ligand is present.", "rule": "mb-deoxy-title", "state_id": "Mb-deoxy", "who": "rule:mb-deoxy-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1MBD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MBD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of sperm whale deoxymoglobin refined at 1.4A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OH"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MBN", "evidence_id": "EV-PDB-1MBN-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MBN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MBN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The stereochemistry of the protein myoglobin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (CARBONMONOXY) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MCY", "evidence_id": "EV-PDB-1MCY-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1MCY", "doi": "10.1074/jbc.270.35.20781", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MCY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE MYOGLOBIN (MUTANT WITH INITIATOR MET AND WITH HIS 64 REPLACED BY GLN, LEU 29 REPLACED BY PHE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "METMYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MGN", "evidence_id": "EV-PDB-1MGN-1", "mappings": [{"confidence": "medium", "justification": "Title says aquomet or metmyoglobin.", "rule": "mb-met-title", "state_id": "Mb-aquomet", "who": "rule:mb-met-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1MGN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MGN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIS64(E7)-> TYR APOMYOGLOBIN AS A REAGENT FOR MEASURING RATES OF HEMIN DISSOCIATION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MLG", "evidence_id": "EV-PDB-1MLG-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MLG", "doi": "10.1006/jmbi.1994.0034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MLG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MLH", "evidence_id": "EV-PDB-1MLH-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MLH", "doi": "10.1006/jmbi.1994.0034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MLH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MLR", "evidence_id": "EV-PDB-1MLR-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MLR", "doi": "10.1006/jmbi.1994.0034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MLR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MLS", "evidence_id": "EV-PDB-1MLS-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1MLS", "doi": "10.1006/jmbi.1994.0034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MLS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural and functional effects of apolar mutations of val68(e11) in myoglobin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MLU", "evidence_id": "EV-PDB-1MLU-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1MLU", "doi": "10.1021/bi00201a005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MLU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NITRIC OXIDE RECOMBINATION TO DOUBLE MUTANTS OF MYOGLOBIN: THE ROLE OF LIGAND DIFFUSION IN A FLUCTUATING HEME POCKET"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MOA", "evidence_id": "EV-PDB-1MOA-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1MOA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MOA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A NOVEL SITE-DIRECTED MUTANT OF MYOGLOBIN WITH AN UNUSUALLY HIGH O2 AFFINITY AND LOW AUTOOXIDATION RATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MOB", "evidence_id": "EV-PDB-1MOB-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1MOB", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MOB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH-RESOLUTION CRYSTAL STRUCTURES OF DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MOC", "evidence_id": "EV-PDB-1MOC-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MOC", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MOC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH-RESOLUTION CRYSTAL STRUCTURES OF DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MOD", "evidence_id": "EV-PDB-1MOD-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MOD", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MOD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH-RESOLUTION CRYSTAL STRUCTURES OF DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MTK", "evidence_id": "EV-PDB-1MTK-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1MTK", "doi": "10.1002/prot.340220404", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MTK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PHE46(CD4) ORIENTS THE DISTAL HISTIDINE FOR HYDROGEN BONDING TO BOUND LIGANDS IN SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MYM", "evidence_id": "EV-PDB-1MYM-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1MYM", "doi": "10.1021/bi00172a021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL DETERMINANTS OF CO STRETCHING VIBRATION FREQUENCIES IN MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MYZ", "evidence_id": "EV-PDB-1MYZ-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1MYZ", "doi": "10.1073/pnas.1430900100", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MYZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CO COMPLEX OF MYOGLOBIN MB-YQR AT RT SOLVED FROM LAUE DATA."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MZ0", "evidence_id": "EV-PDB-1MZ0-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1MZ0", "doi": "10.1073/pnas.1430900100", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MZ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF MYOGLOBIN MB-YQR 316 ns AFTER PHOTOLYSIS OF CARBON MONOXIDE SOLVED FROM LAUE DATA AT RT."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MYF", "evidence_id": "EV-PDB-1MYF-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1MYF", "doi": "10.1006/jmbi.1994.1718", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MYF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF CARBONMONOXY MYOGLOBIN DETERMINED FROM NMR DISTANCE AND CHEMICAL SHIFT CONSTRAINTS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MTJ", "evidence_id": "EV-PDB-1MTJ-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1MTJ", "doi": "10.1002/prot.340220404", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PHE46(CD4) ORIENTS THE DISTAL HISTIDINE FOR HYDROGEN BONDING TO BOUND LIGANDS IN SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MTI", "evidence_id": "EV-PDB-1MTI-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1MTI", "doi": "10.1002/prot.340220404", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PHE46(CD4) ORIENTS THE DISTAL HISTIDINE FOR HYDROGEN BONDING TO BOUND LIGANDS IN SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MLF", "evidence_id": "EV-PDB-1MLF-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MLF", "doi": "10.1006/jmbi.1994.0034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MLF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OXY", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MBO", "evidence_id": "EV-PDB-1MBO-1", "mappings": [{"confidence": "high", "justification": "O2 (ligand OXY) bound to the heme.", "rule": "mb-o2-ligand", "state_id": "Mb-oxy", "who": "rule:mb-o2-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1MBO", "doi": "10.1016/0022-2836(80)90262-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MBO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure and refinement of oxymyoglobin at 1.6 angstroms resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "IMD", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MBI", "evidence_id": "EV-PDB-1MBI-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MBI", "doi": "10.1016/0022-2836(91)90744-Q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MBI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "ND4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1L2K", "evidence_id": "EV-PDB-1L2K-1", "mappings": [{"confidence": "medium", "justification": "Title says aquomet or metmyoglobin.", "rule": "mb-met-title", "state_id": "Mb-aquomet", "who": "rule:mb-met-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1L2K", "doi": "10.1016/S0301-4622(01)00255-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1L2K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "neutron", "title": "Neutron Structure Determination of Sperm Whale Met-Myoglobin at 1.5A Resolution."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JP8", "evidence_id": "EV-PDB-1JP8-1", "mappings": [{"confidence": "medium", "justification": "Title says aquomet or metmyoglobin.", "rule": "mb-met-title", "state_id": "Mb-aquomet", "who": "rule:mb-met-title"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1JP8", "doi": "10.1016/S0969-2126(01)00699-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Sperm Whale met-Myoglobin (room temperature; high pressure)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FCS", "evidence_id": "EV-PDB-1FCS-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1FCS", "doi": "10.1016/0014-5793(93)81647-I", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FCS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF A DISTAL SITE DOUBLE MUTANT OF SPERM WHALE MYOGLOBIN AT 1.6 ANGSTROMS RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OH", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1N9H", "evidence_id": "EV-PDB-1N9H-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1N9H", "doi": "10.1107/S0907444903005924", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1N9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "structure of microgravity-grown oxidized myoglobin mutant YQR (ISS6A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OH", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1N9I", "evidence_id": "EV-PDB-1N9I-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1N9I", "doi": "10.1107/S0907444903005924", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1N9I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "structure of earth-grown oxidized myoglobin mutant YQR (ISS8A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OH", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1N9X", "evidence_id": "EV-PDB-1N9X-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1N9X", "doi": "10.1107/S0907444903005924", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1N9X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "structure of microgravity-grown oxidized myoglobin mutant YQR (ISS8A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OH", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NAZ", "evidence_id": "EV-PDB-1NAZ-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.04}, "provenance": {"deposit_id": "1NAZ", "doi": "10.1107/S0907444903005924", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NAZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "structure of microgravity-grown oxidized myoglobin mutant YQR (ISS8A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1O16", "evidence_id": "EV-PDB-1O16-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "1O16", "doi": "10.1021/bi034605u", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1O16"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN H64D/V68S/D122N MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OBM", "evidence_id": "EV-PDB-1OBM-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1OBM", "doi": "10.1074/jbc.273.16.9517", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OBM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN 29F/64Q/68F/122N MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OFJ", "evidence_id": "EV-PDB-1OFJ-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1OFJ", "doi": "10.1074/jbc.274.5.2838", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OFJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN L29H/H64L/D122N MUTANT (WITH INITIATOR MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OFK", "evidence_id": "EV-PDB-1OFK-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1OFK", "doi": "10.1074/jbc.274.5.2838", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OFK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN F43H, H64L MUTANT (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SPE", "evidence_id": "EV-PDB-1SPE-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1SPE", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SPE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SPERM WHALE NATIVE CO MYOGLOBIN AT PH 4.0, TEMP 4C"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ETN", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TES", "evidence_id": "EV-PDB-1TES-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1TES", "doi": "10.1021/bi960442g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "OXYGEN BINDING MUSCLE PROTEIN"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1U7S", "evidence_id": "EV-PDB-1U7S-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1U7S", "doi": "10.1002/prot.21499", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1U7S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Native Sperm Whale myoglobin from low ionic strength enviroment (Form 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CZM", "FE", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UFJ", "evidence_id": "EV-PDB-1UFJ-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "1UFJ", "doi": "10.1021/ic0498539", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UFJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an Artificial Metalloprotein:Fe(III)(3,3'-Me2-salophen)/apo-A71G Myoglobin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UFP", "evidence_id": "EV-PDB-1UFP-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1UFP", "doi": "10.1021/ic0498539", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UFP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an Artificial Metalloprotein:Fe(III)(3,3'-Me2-salophen)/apo-wild type Myoglobin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CZM", "MN3", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1V9Q", "evidence_id": "EV-PDB-1V9Q-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "1V9Q", "doi": "10.1021/ja045995q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1V9Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an Artificial Metalloprotein:Mn(III)(3,3'-Me2-salophen)/apo-A71G Myoglobin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXA", "evidence_id": "EV-PDB-1VXA-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1VXA", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXB", "evidence_id": "EV-PDB-1VXB-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1VXB", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXC", "evidence_id": "EV-PDB-1VXC-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1VXC", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXD", "evidence_id": "EV-PDB-1VXD-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1VXD", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXF", "evidence_id": "EV-PDB-1VXF-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1VXF", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXG", "evidence_id": "EV-PDB-1VXG-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1VXG", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXH", "evidence_id": "EV-PDB-1VXH-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1VXH", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WVP", "evidence_id": "EV-PDB-1WVP-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "1WVP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WVP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of chemically modified myoglobin with distal N-tetrazolyl-histidine E7(64)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "MYOGLOBIN (chains M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2BLJ", "evidence_id": "EV-PDB-2BLJ-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2BLJ", "doi": "10.1021/BI047513T", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2BLJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of L29W MbCO"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "MYOGLOBIN (chains M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2BW9", "evidence_id": "EV-PDB-2BW9-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.68}, "provenance": {"deposit_id": "2BW9", "doi": "10.1073/PNAS.0504932102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2BW9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Laue Structure of L29W MbCO"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["7HE", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EKU", "evidence_id": "EV-PDB-2EKU-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "2EKU", "doi": "10.1021/bi7007068", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EKU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of myoglobin reconstituted with 7-methyl-7-depropionatehemin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACY", "HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EVK", "evidence_id": "EV-PDB-2EVK-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "2EVK", "doi": "10.1021/bi052171s", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EVK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "HEM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EVP", "evidence_id": "EV-PDB-2EVP-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2EVP", "doi": "10.1021/bi052171s", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EVP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G0R", "evidence_id": "EV-PDB-2G0R-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "2G0R", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G0R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Unphotolyzed CO-bound L29F Myoglobin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G0S", "evidence_id": "EV-PDB-2G0S-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2G0S", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G0S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Unphotolyzed CO-bound L29F Myoglobin, crystal 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G0V", "evidence_id": "EV-PDB-2G0V-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "2G0V", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G0V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO L29F Myoglobin: 100ps"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G0X", "evidence_id": "EV-PDB-2G0X-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "2G0X", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO L29F Myoglobin: 316ps"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G0Z", "evidence_id": "EV-PDB-2G0Z-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "2G0Z", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G0Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO L29F Myoglobin: 1ns"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G10", "evidence_id": "EV-PDB-2G10-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2G10", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G10"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO L29F Myoglobin: 3.16ns"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G11", "evidence_id": "EV-PDB-2G11-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2G11", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G11"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO L29F Myoglobin: 31.6ns"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VXE", "evidence_id": "EV-PDB-1VXE-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1VXE", "doi": "10.1006/jmbi.1996.0123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VXE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NATIVE SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G12", "evidence_id": "EV-PDB-2G12-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2G12", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G12"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO L29F Myoglobin: 316ns"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G14", "evidence_id": "EV-PDB-2G14-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2G14", "doi": "10.1107/S0907444906017318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photolyzed CO L29F Myoglobin: 3.16us"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "ND4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MB5", "evidence_id": "EV-PDB-2MB5-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2MB5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "neutron", "title": "HYDRATION IN PROTEIN CRYSTALS. A NEUTRON DIFFRACTION ANALYSIS OF CARBONMONOXYMYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MBW", "evidence_id": "EV-PDB-2MBW-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "2MBW", "doi": "10.1074/jbc.271.41.25419", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MBW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RECOMBINANT SPERM WHALE MYOGLOBIN (MET)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGA", "evidence_id": "EV-PDB-2MGA-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "2MGA", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGB", "evidence_id": "EV-PDB-2MGB-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2MGB", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGC", "evidence_id": "EV-PDB-2MGC-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2MGC", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGD", "evidence_id": "EV-PDB-2MGD-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2MGD", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGE", "evidence_id": "EV-PDB-2MGE-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2MGE", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGF", "evidence_id": "EV-PDB-2MGF-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2MGF", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGG", "evidence_id": "EV-PDB-2MGG-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2MGG", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGH", "evidence_id": "EV-PDB-2MGH-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2MGH", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGI", "evidence_id": "EV-PDB-2MGI-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2MGI", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGJ", "evidence_id": "EV-PDB-2MGJ-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2MGJ", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGK", "evidence_id": "EV-PDB-2MGK-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2MGK", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGL", "evidence_id": "EV-PDB-2MGL-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2MGL", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OXY", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MGM", "evidence_id": "EV-PDB-2MGM-1", "mappings": [{"confidence": "high", "justification": "O2 (ligand OXY) bound to the heme.", "rule": "mb-o2-ligand", "state_id": "Mb-oxy", "who": "rule:mb-o2-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2MGM", "doi": "10.1006/jmbi.1993.1569", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MGM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ENC", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (ETHYL ISOCYANIDE) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MYA", "evidence_id": "EV-PDB-2MYA-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2MYA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MYA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "MNC", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (METHYL ISOCYANIDE) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MYB", "evidence_id": "EV-PDB-2MYB-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2MYB", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MYB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NBN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (N-BUTYL ISOCYANIDE) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MYC", "evidence_id": "EV-PDB-2MYC-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2MYC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MYC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "NPN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (N-PROPYL ISOCYANIDE) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MYD", "evidence_id": "EV-PDB-2MYD-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2MYD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MYD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ENC", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (ETHYL ISOCYANIDE) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MYE", "evidence_id": "EV-PDB-2MYE-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.68}, "provenance": {"deposit_id": "2MYE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MYE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION X-RAY STRUCTURES OF MYOGLOBIN-AND HEMOGLOBIN-ALKYL ISOCYANIDE COMPLEXES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OH8", "evidence_id": "EV-PDB-2OH8-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2OH8", "doi": "10.1080/15216540701230495", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OH8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Myoglobin cavity mutant I28W"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OH9", "evidence_id": "EV-PDB-2OH9-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2OH9", "doi": "10.1080/15216540701230495", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OH9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Myoglobin cavity mutant V68W"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OHA", "evidence_id": "EV-PDB-2OHA-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2OHA", "doi": "10.1080/15216540701230495", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OHA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Myoglobin cavity mutant F138W"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Myoglobin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OHB", "evidence_id": "EV-PDB-2OHB-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2OHB", "doi": "10.1080/15216540701230495", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OHB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Myoglobin cavity mutant I107W"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2SPL", "evidence_id": "EV-PDB-2SPL-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2SPL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2SPL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A NOVEL SITE-DIRECTED MUTANT OF MYOGLOBIN WITH AN UNUSUALLY HIGH O2 AFFINITY AND LOW AUTOOXIDATION RATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2SPM", "evidence_id": "EV-PDB-2SPM-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2SPM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2SPM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A NOVEL SITE-DIRECTED MUTANT OF MYOGLOBIN WITH AN UNUSUALLY HIGH O2 AFFINITY AND LOW AUTOOXIDATION RATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "OXY", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2SPN", "evidence_id": "EV-PDB-2SPN-1", "mappings": [{"confidence": "high", "justification": "O2 (ligand OXY) bound to the heme.", "rule": "mb-o2-ligand", "state_id": "Mb-oxy", "who": "rule:mb-o2-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2SPN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2SPN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A NOVEL SITE-DIRECTED MUTANT OF MYOGLOBIN WITH AN UNUSUALLY HIGH O2 AFFINITY AND LOW AUTOOXIDATION RATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2SPO", "evidence_id": "EV-PDB-2SPO-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2SPO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2SPO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A NOVEL SITE-DIRECTED MUTANT OF MYOGLOBIN WITH AN UNUSUALLY HIGH O2 AFFINITY AND LOW AUTOOXIDATION RATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "HEM", "SO4", "XE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2W6W", "evidence_id": "EV-PDB-2W6W-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "2W6W", "doi": "10.1002/BIP.21201", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2W6W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of recombinant Sperm Whale Myoglobin under 1atm of Xenon"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4", "XE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2W6X", "evidence_id": "EV-PDB-2W6X-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.73}, "provenance": {"deposit_id": "2W6X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2W6X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Sperm Whale Myoglobin mutant YQRF in complex with Xenon"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEM", "SO4", "XE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOGLOBIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2W6Y", "evidence_id": "EV-PDB-2W6Y-1", "mappings": [], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "2W6Y", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2W6Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Sperm Whale Myoglobin mutant YQR in complex with Xenon"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMO", "HEM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Myoglobin, CO-bound (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N03", "evidence_id": "EV-PDB-6N03-1", "mappings": [{"confidence": "high", "justification": "CO (ligand CMO) bound to the heme.", "rule": "mb-co-ligand", "state_id": "Mb-CO", "who": "rule:mb-co-ligand"}], "molecule_id": "P02185", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "6N03", "doi": "10.1107/S2052252519001453", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N03"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CO-bound Sperm Whale Myoglobin, room temperature structure, last 2 degrees of 5 degree total oscillation and 160 kGy dose"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Prelamin-A/C,Microtubule-associated protein RP/EB family member 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YF5", "evidence_id": "EV-PDB-6YF5-1", "mappings": [], "molecule_id": "P02545", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "6YF5", "doi": "10.3390/cells9071633", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YF5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lamin A 17-70 coil1A dimer stabilized by C-terminal capping"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LYS-ALA-GLY-GLN-VAL-VAL-THR-ILE (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7X1B", "evidence_id": "EV-PDB-7X1B-3", "mappings": [], "molecule_id": "P02545", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.399}, "provenance": {"deposit_id": "7X1B", "doi": "10.1038/s41598-023-36293-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7X1B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of peptide KAGQVVTI in complex with HLA-B5801"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lamin-A/C (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9J8M", "evidence_id": "EV-PDB-9J8M-8", "mappings": [], "molecule_id": "P02545", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.82}, "provenance": {"deposit_id": "9J8M", "doi": "10.1038/s41467-025-56823-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9J8M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (High mobility complex)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lamin-A/C (chains M,P,m,p)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9J8N", "evidence_id": "EV-PDB-9J8N-8", "mappings": [], "molecule_id": "P02545", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.14}, "provenance": {"deposit_id": "9J8N", "doi": "10.1038/s41467-025-56823-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9J8N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (Low mobility complex)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Prelamin-A/C (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I33", "evidence_id": "EV-PDB-8I33-1", "mappings": [], "molecule_id": "P02545", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.62}, "provenance": {"deposit_id": "8I33", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I33"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Coil 1a of lamin A (residue 25-65)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Lamin-A/C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D9N", "evidence_id": "EV-PDB-7D9N-1", "mappings": [], "molecule_id": "P02545", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7D9N", "doi": "10.1038/s42003-022-03212-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D9N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a non-canonic progeria mutation S143F at lamin A/C and its structural implication to the premature aging"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Prelamin-A/C (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CRG", "evidence_id": "EV-PDB-7CRG-1", "mappings": [], "molecule_id": "P02545", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "7CRG", "doi": "10.1016/j.bbrc.2021.02.102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CRG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Beta-strand-mediated dimeric formation of the extended Ig-like domains of human lamin A/C"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIBRONECTIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CG7", "evidence_id": "EV-PDB-2CG7-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.2}, "provenance": {"deposit_id": "2CG7", "doi": "10.1016/J.JMB.2007.02.061", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CG7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SECOND AND THIRD FIBRONECTIN TYPE I MODULE PAIR (CRYSTAL FORM II)."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MMX", "evidence_id": "EV-PDB-4MMX-3", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "4MMX", "doi": "10.1038/nsmb.2797", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MMX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MMY", "evidence_id": "EV-PDB-4MMY-3", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.183}, "provenance": {"deposit_id": "4MMY", "doi": "10.1038/nsmb.2797", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MN", "NA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MMZ", "evidence_id": "EV-PDB-4MMZ-3", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "4MMZ", "doi": "10.1038/nsmb.2797", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MMZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Integrin AlphaVBeta3 ectodomain bound to an antagonistic tenth domain of Fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PZ5", "evidence_id": "EV-PDB-4PZ5-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "4PZ5", "doi": "10.1074/jbc.M114.578419", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PZ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of BBK32 from Borrelia burgdorferi"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DC0", "evidence_id": "EV-PDB-5DC0-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.23}, "provenance": {"deposit_id": "5DC0", "doi": "10.1074/jbc.M115.707901", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DC0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF MONOBODY GG3/ABL1 SH2 DOMAIN COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.83, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "AS25 monobody (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DC4", "evidence_id": "EV-PDB-5DC4-2", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "5DC4", "doi": "10.1074/jbc.M115.707901", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GH7", "evidence_id": "EV-PDB-4GH7-2", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "4GH7", "doi": "10.1016/j.jmb.2012.12.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GH7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIBRONECTIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ZRZ", "evidence_id": "EV-PDB-3ZRZ-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3ZRZ", "doi": "10.1074/JBC.M111.276592", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ZRZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of Streptococcus pyogenes SfbI-5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GXE", "evidence_id": "EV-PDB-3GXE-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "3GXE", "doi": "10.1074/jbc.M113.469841", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GXE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex of a Low Affinity Collagen Site with the Fibronectin 8-9FnI Domain Pair"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SIN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RKZ", "evidence_id": "EV-PDB-2RKZ-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2RKZ", "doi": "10.1073/pnas.0803556105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RKZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the second and third fibronectin f1 modules in complex with a fragment of staphylococcus aureus fnbpa-1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "PROTEIN (FIBRONECTIN) (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QGB", "evidence_id": "EV-PDB-1QGB-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1QGB", "doi": "10.1021/bi990202b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QGB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF THE N-TERMINAL F1 MODULE PAIR FROM HUMAN FIBRONECTIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "FIBRONECTIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1O9A", "evidence_id": "EV-PDB-1O9A-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1O9A", "doi": "10.1038/nature01589", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1O9A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the complex of 1F12F1 from fibronectin with B3 from FnBB from S. dysgalactiae"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "FIBRONECTIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1J8K", "evidence_id": "EV-PDB-1J8K-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1J8K", "doi": "10.1023/A:1012947209393", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1J8K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR STRUCTURE OF THE FIBRONECTIN EDA DOMAIN, NMR, 20 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN (FIBRONECTIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FNH", "evidence_id": "EV-PDB-1FNH-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1FNH", "doi": "10.1093/emboj/18.6.1468", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FNH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HEPARIN AND INTEGRIN BINDING SEGMENT OF HUMAN FIBRONECTIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "FIBRONECTIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FBR", "evidence_id": "EV-PDB-1FBR-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1FBR", "doi": "10.1006/jmbi.1994.1083", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FBR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "FOURTH AND FIFTH FIBRONECTIN TYPE I MODULE PAIR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Fibronectin (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J6Z", "evidence_id": "EV-PDB-5J6Z-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "5J6Z", "doi": "10.1021/acs.biochem.7b00633", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J6Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Fibronectin (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5M0A", "evidence_id": "EV-PDB-5M0A-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "5M0A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5M0A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of isolated 15th Fibronectin III domain from human fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains B,D,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5N47", "evidence_id": "EV-PDB-5N47-2", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "5N47", "doi": "10.1016/j.str.2018.02.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5N47"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5N48", "evidence_id": "EV-PDB-5N48-2", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "5N48", "doi": "10.1016/j.str.2018.02.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5N48"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MFA", "evidence_id": "EV-PDB-6MFA-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.754}, "provenance": {"deposit_id": "6MFA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MFA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment of human fibronectin containing the 4th-7th type III domains"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MSV", "evidence_id": "EV-PDB-6MSV-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "6MSV", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MSV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the 6th type III domain from human fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin, HR10 variant (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6NAJ", "evidence_id": "EV-PDB-6NAJ-3", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "6NAJ", "doi": "10.1038/s41467-019-13928-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6NAJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fibronectin (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XAY", "evidence_id": "EV-PDB-6XAY-1", "mappings": [], "molecule_id": "P02751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.48}, "provenance": {"deposit_id": "6XAY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XAY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a fragment of human fibronectin containing the 10th, 11th and 12th type III domains"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Fibronectin (chains B)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A3X", "evidence_id": "EV-PDB-9A3X-2", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A3X", "doi": "10.1016/j.matbio.2023.12.006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A3X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Predicted model of tissue transglutaminase 2 (TG2) in complex with plasma fibronectin type I modules 2 and 3 (FNI2-3)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Fibronectin (chains B)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A3Z", "evidence_id": "EV-PDB-9A3Z-2", "mappings": [], "molecule_id": "P02751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A3Z", "doi": "10.1016/j.matbio.2023.12.006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A3Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "A predicted model of tissue transglutaminase 2 (TG2) in complex with plasma fibronectin's gelatin binding domain (FNI6FNII1-2FNI7-9)."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.5, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25564", "evidence_id": "EV-BMRB-25564", "mappings": [], "molecule_id": "P02751", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25564", "doi": "10.13018/BMR25564", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25564"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Structure of the Third Type III Domain from Human Fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=27610", "evidence_id": "EV-BMRB-27610", "mappings": [], "molecule_id": "P02751", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr27610", "doi": "10.13018/BMR27610", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=27610"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Sequence-specific 1H, 13C, and 15N backbone assignment of Fibronectin type III 14"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30061", "evidence_id": "EV-BMRB-30061", "mappings": [], "molecule_id": "P02751", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30061", "doi": "10.13018/BMR30061", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30061"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34048", "evidence_id": "EV-BMRB-34048", "mappings": [], "molecule_id": "P02751", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr34048", "doi": "10.13018/BMR34048", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34048"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of isolated 15th Fibronectin III domain from human fibronectin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1FNA; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A00FZ/overview", "evidence_id": "EV-MDDB-A00FZ", "mappings": [], "molecule_id": "P02751", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A00FZ", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A00FZ/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1FNA"}
{"components": [], "domains": [], "gene": "HSP82", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P02829"}, "ligands": ["ATP"], "modifications": [{"kind": "ptm", "name": "Phosphoserine", "position": 657, "source": "UniProtKB"}], "molecule_id": "P02829", "molecule_type": "protein", "name": "ATP-dependent molecular chaperone HSP82", "organism": {"name": "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "taxon_id": 559292}, "provenance": {"deposit_id": "P02829", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02829/entry"}, "record_type": "molecule", "sequence": "MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEASTAAPVEEVPADTEMEEVD", "sequence_length": 709}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GDM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "HEAT SHOCK PROTEIN 90 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1A4H", "evidence_id": "EV-PDB-1A4H-1", "mappings": [], "molecule_id": "P02829", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1A4H", "doi": "10.1016/S0092-8674(00)80314-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1A4H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE IN COMPLEX WITH GELDANAMYCIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "HEAT SHOCK PROTEIN 90 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AMW", "evidence_id": "EV-PDB-1AMW-1", "mappings": [], "molecule_id": "P02829", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1AMW", "doi": "10.1016/S0092-8674(00)80314-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AMW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ADP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RDC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "HEAT SHOCK PROTEIN 90 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BGQ", "evidence_id": "EV-PDB-1BGQ-1", "mappings": [], "molecule_id": "P02829", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1BGQ", "doi": "10.1021/jm980403y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BGQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RADICICOL BOUND TO THE ATP BINDING SITE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP82 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HK7", "evidence_id": "EV-PDB-1HK7-1", "mappings": [], "molecule_id": "P02829", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1HK7", "doi": "10.1016/S1097-2765(03)00065-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HK7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Middle Domain of HSP90"}
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{"components": [], "domains": [], "gene": "rbsB", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P02925"}, "ligands": [], "modifications": [], "molecule_id": "P02925", "molecule_type": "protein", "name": "Ribose import binding protein RbsB", "organism": {"name": "Escherichia coli (strain K12)", "taxon_id": 83333}, "provenance": {"deposit_id": "P02925", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02925/entry"}, "record_type": "molecule", "sequence": "MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSLKDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKMANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGTSAARERGEGFQQAVAAHKFNVLASQPADFDRIKGLNVMQNLLTAHPDVQAVFAQNDEMALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKVLKGEKVQAKYPVDLKLVVKQ", "sequence_length": 296}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RIP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "D-RIBOSE-BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DRJ", "evidence_id": "EV-PDB-1DRJ-1", "mappings": [{"confidence": "high", "justification": "Ribose (RIP) bound closes the two domains.", "rule": "rbp-ribose-closed", "state_id": "RBP-closed", "who": "rule:rbp-ribose-closed"}], "molecule_id": "P02925", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1DRJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DRJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PROBING PROTEIN-PROTEIN INTERACTIONS: THE RIBOSE-BINDING PROTEIN IN BACTERIAL TRANSPORT AND CHEMOTAXIS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RIP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "D-ribose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2GX6", "evidence_id": "EV-PDB-2GX6-1", "mappings": [{"confidence": "high", "justification": "Ribose (RIP) bound closes the two domains.", "rule": "rbp-ribose-closed", "state_id": "RBP-closed", "who": "rule:rbp-ribose-closed"}], "molecule_id": "P02925", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.97}, "provenance": {"deposit_id": "2GX6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2GX6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Rational stabilization of E. coli ribose binding protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AT9", "evidence_id": "EV-PDB-1AT9-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1AT9", "doi": "10.1038/38323", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AT9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "STRUCTURE OF BACTERIORHODOPSIN AT 3.0 ANGSTROM DETERMINED BY ELECTRON CRYSTALLOGRAPHY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BCT", "evidence_id": "EV-PDB-1BCT-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BCT", "doi": "10.1111/j.1432-1033.1992.tb16972.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BCT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THREE-DIMENSIONAL STRUCTURE OF PROTEOLYTIC FRAGMENT 163-231 OF BACTERIOOPSIN DETERMINED FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BHA", "evidence_id": "EV-PDB-1BHA-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BHA", "doi": "10.1111/j.1432-1033.1994.tb19973.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BHA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THREE-DIMENSIONAL STRUCTURE OF (1-71) BACTERIOOPSIN SOLUBILIZED IN METHANOL-CHLOROFORM AND SDS MICELLES DETERMINED BY 15N-1H HETERONUCLEAR NMR SPECTROSCOPY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BHB", "evidence_id": "EV-PDB-1BHB-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BHB", "doi": "10.1111/j.1432-1033.1994.tb19973.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BHB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Three-dimensional structure of (1-71) bacterioopsin solubilized in methanol-chloroform and SDS micelles determined by 15N-1H heteronuclear NMR spectroscopy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DPG", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BM1", "evidence_id": "EV-PDB-1BM1-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "1BM1", "doi": "10.1107/S090744499900503X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BM1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN THE LIGHT-ADAPTED STATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BACTERIORHODOPSIN PRECURSOR (chains A)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BRD", "evidence_id": "EV-PDB-1BRD-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "1BRD", "doi": "10.1016/S0022-2836(05)80271-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BRD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "Model for the structure of Bacteriorhodopsin based on high-resolution Electron Cryo-microscopy"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BRX", "evidence_id": "EV-PDB-1BRX-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1BRX", "doi": "10.1126/science.280.5371.1934", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BRX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN/LIPID COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN (BACTERIORHODOPSIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1C8R", "evidence_id": "EV-PDB-1C8R-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1C8R", "doi": "10.1126/science.286.5438.255", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1C8R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN D96N BR STATE AT 2.0 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (\"M\" STATE INTERMEDIATE) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1C8S", "evidence_id": "EV-PDB-1C8S-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1C8S", "doi": "10.1126/science.286.5438.255", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1C8S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN D96N LATE M STATE INTERMEDIATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEX", "OCT", "RET", "TRD", "UND"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (\"M\" STATE INTERMEDIATE IN COMBINATION WITH GROUND STATE) (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWQ", "evidence_id": "EV-PDB-1CWQ-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "1CWQ", "doi": "10.1038/35020607", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "M INTERMEDIATE STRUCTURE OF THE WILD TYPE BACTERIORHODOPSIN IN COMBINATION WITH THE GROUND STATE STRUCTURE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FBB", "evidence_id": "EV-PDB-1FBB-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "1FBB", "doi": "10.1038/35020614", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FBB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "CRYSTAL STRUCTURE OF NATIVE CONFORMATION OF BACTERIORHODOPSIN"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["L2P", "L3P", "RET", "branched: beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IW9", "evidence_id": "EV-PDB-1IW9-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1IW9", "doi": "10.1016/j.jmb.2004.06.080", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IW9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the M Intermediate of Bacteriorhodopsin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JV6", "evidence_id": "EV-PDB-1JV6-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1JV6", "doi": "10.1006/jmbi.2001.5066", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JV6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN D85S/F219L DOUBLE MUTANT AT 2.00 ANGSTROM RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JV7", "evidence_id": "EV-PDB-1JV7-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "1JV7", "doi": "10.1006/jmbi.2001.5066", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JV7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN O-LIKE INTERMEDIATE STATE OF THE D85S MUTANT AT 2.25 ANGSTROM RESOLUTION"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1L0M", "evidence_id": "EV-PDB-1L0M-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1L0M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1L0M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of Bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1M0K", "evidence_id": "EV-PDB-1M0K-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.43}, "provenance": {"deposit_id": "1M0K", "doi": "10.1016/S0022-2836(02)00681-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1M0K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN K INTERMEDIATE AT 1.43 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1M0L", "evidence_id": "EV-PDB-1M0L-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.47}, "provenance": {"deposit_id": "1M0L", "doi": "10.1016/S0022-2836(02)00681-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1M0L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN/LIPID COMPLEX AT 1.47 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1M0M", "evidence_id": "EV-PDB-1M0M-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.43}, "provenance": {"deposit_id": "1M0M", "doi": "10.1016/S0022-2836(02)00682-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1M0M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN M1 INTERMEDIATE AT 1.43 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BR", "K", "LI1", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MGY", "evidence_id": "EV-PDB-1MGY-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MGY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MGY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the D85S mutant of bacteriorhodopsin with bromide bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1O0A", "evidence_id": "EV-PDB-1O0A-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.62}, "provenance": {"deposit_id": "1O0A", "doi": "10.1016/S0022-2836(03)00263-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1O0A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN L INTERMEDIATE AT 1.62 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1P8I", "evidence_id": "EV-PDB-1P8I-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "1P8I", "doi": "10.1016/S0022-2836(03)00576-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1P8I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "F219L BACTERIORHODOPSIN MUTANT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1P8U", "evidence_id": "EV-PDB-1P8U-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.62}, "provenance": {"deposit_id": "1P8U", "doi": "10.1016/S0022-2836(03)00576-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1P8U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN N' INTERMEDIATE AT 1.62 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PXR", "evidence_id": "EV-PDB-1PXR-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1PXR", "doi": "10.1016/j.jmb.2003.10.041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PXR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pro50Ala mutant of Bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PXS", "evidence_id": "EV-PDB-1PXS-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1PXS", "doi": "10.1016/j.jmb.2003.10.041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PXS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Met56Ala mutant of Bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PY6", "evidence_id": "EV-PDB-1PY6-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1PY6", "doi": "10.1016/j.jmb.2003.10.041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PY6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Bacteriorhodopsin crystallized from bicells"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Q5I", "evidence_id": "EV-PDB-1Q5I-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1Q5I", "doi": "10.1073/pnas.0306077101", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Q5I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of bacteriorhodopsin mutant P186A crystallized from bicelles"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PH1", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN (BACTERIORHODOPSIN) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QHJ", "evidence_id": "EV-PDB-1QHJ-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1QHJ", "doi": "10.1016/S0969-2126(99)80118-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QHJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY STRUCTURE OF BACTERIORHODOPSIN GROWN IN LIPIDIC CUBIC PHASES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QKO", "evidence_id": "EV-PDB-1QKO-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1QKO", "doi": "10.1038/44623", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QKO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION X-RAY STRUCTURE OF AN EARLY INTERMEDIATE IN THE BACTERIORHODOPSIN PHOTOCYCLE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QKP", "evidence_id": "EV-PDB-1QKP-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1QKP", "doi": "10.1038/44623", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QKP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH RESOLUTION X-RAY STRUCTURE OF AN EARLY INTERMEDIATE IN THE BACTERIORHODOPSIN PHOTOCYCLE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["L1P", "L2P", "L3P", "L4P", "RET", "branched: beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QM8", "evidence_id": "EV-PDB-1QM8-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1QM8", "doi": "10.1006/JMBI.1998.2103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QM8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Bacteriorhodopsin at 100 K"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Q5J", "evidence_id": "EV-PDB-1Q5J-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1Q5J", "doi": "10.1073/pnas.0306077101", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Q5J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of bacteriorhodopsin mutant P91A crystallized from bicelles"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BGC", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KME", "evidence_id": "EV-PDB-1KME-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1KME", "doi": "10.1006/jmbi.2001.5295", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KME"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF BACTERIORHODOPSIN CRYSTALLIZED FROM BICELLES"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1F4Z", "evidence_id": "EV-PDB-1F4Z-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1F4Z", "doi": "10.1006/jmbi.2000.3884", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1F4Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN-M PHOTOINTERMEDIATE STATE OF THE E204Q MUTANT AT 1.8 ANGSTROM RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "BACTERIORHODOPSIN, GROUND STATE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1E0P", "evidence_id": "EV-PDB-1E0P-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1E0P", "doi": "10.1038/35020599", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1E0P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "L intermediate of bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET", "SQU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BACTERIORHODOPSIN (GROUND STATE WILD TYPE \"BR\") (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1C3W", "evidence_id": "EV-PDB-1C3W-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "1C3W", "doi": "10.1006/jmbi.1999.3027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1C3W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BACTERIORHODOPSIN/LIPID COMPLEX AT 1.55 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1S53", "evidence_id": "EV-PDB-1S53-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1S53", "doi": "10.1021/ja0317574", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1S53"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Thr46Ser Bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1S54", "evidence_id": "EV-PDB-1S54-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1S54", "doi": "10.1021/ja0317574", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1S54"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Thr24Ala Bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "NO3", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin precursor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1S8J", "evidence_id": "EV-PDB-1S8J-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1S8J", "doi": "10.1021/bi035757s", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1S8J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nitrate-bound D85S mutant of bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TN0", "evidence_id": "EV-PDB-1TN0-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1TN0", "doi": "10.1016/j.jmb.2004.06.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TN0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of bacterorhodopsin mutant A51P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["L2P", "L3P", "RET", "branched: beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UCQ", "evidence_id": "EV-PDB-1UCQ-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "1UCQ", "doi": "10.1016/j.jmb.2003.10.068", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UCQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the L intermediate of bacteriorhodopsin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NTU", "evidence_id": "EV-PDB-2NTU-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "2NTU", "doi": "10.1016/j.jmb.2006.11.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NTU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Bacteriorhodopsin, wild type, before illumination"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3COD", "evidence_id": "EV-PDB-3COD-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "3COD", "doi": "10.1038/nature06977", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3COD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of T90A/D115A mutant of Bacteriorhodopsin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BXC", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MBV", "evidence_id": "EV-PDB-3MBV-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3MBV", "doi": "10.1016/j.jcrysgro.2010.08.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of bacterirhodopsin crystallized in betta-XylOC(16+4) meso phase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3NS0", "evidence_id": "EV-PDB-3NS0-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.78}, "provenance": {"deposit_id": "3NS0", "doi": "10.1016/j.jmb.2011.04.038", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3NS0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of bacteriorhodopsin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3NSB", "evidence_id": "EV-PDB-3NSB-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.78}, "provenance": {"deposit_id": "3NSB", "doi": "10.1016/j.jmb.2011.04.038", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3NSB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of bacteriorhodopsin ground state before and after X-ray modification"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LI1", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (GROUND STATE) (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3T45", "evidence_id": "EV-PDB-3T45-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "3T45", "doi": "10.1016/j.jmb.2011.11.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3T45"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of bacteriorhodopsin mutant A215T, a phototaxis signaling mutant at 3.0 A resolution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BOG", "MC3", "RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3UTW", "evidence_id": "EV-PDB-3UTW-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "3UTW", "doi": "10.1073/pnas.1201298109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3UTW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of bacteriorhodopsin mutant P50A/Y57F"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RET"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OV0", "evidence_id": "EV-PDB-4OV0-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4OV0", "doi": "10.1007/s00232-014-9700-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OV0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Bacteriorhdopsin Transferred from Amphipol A8-35 to a Lipidic Mesophase"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["L1P", "L2P", "L3P", "RET", "SOG", "branched: 3-O-sulfo-beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZZL", "evidence_id": "EV-PDB-2ZZL-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.03}, "provenance": {"deposit_id": "2ZZL", "doi": "10.1016/j.jmb.2009.08.047", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ZZL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of bacteriorhodopsin's M intermediate at pH 7"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["C14", "D10", "DD9", "HP6", "L2P", "MYS", "OCT", "RET", "TRD", "UND"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Bacteriorhodopsin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6GA3", "evidence_id": "EV-PDB-6GA3-1", "mappings": [], "molecule_id": "P02945", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "6GA3", "doi": "10.1038/s41467-019-10758-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6GA3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Bacteriorhodopsin, 33 ms state, ensemble refinement"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NPF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "LAC REPRESSOR (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EFA", "evidence_id": "EV-PDB-1EFA-2", "mappings": [{"confidence": "high", "justification": "Repressor bound to operator DNA with ONPF; representative for the operator-bound state.", "rule": "curator_assignment", "state_id": "LacI-operator", "who": "curator:draft (unreviewed)"}], "molecule_id": "P03023", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1EFA", "doi": "10.1038/78907", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EFA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lac repressor (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4RZS", "evidence_id": "EV-PDB-4RZS-1", "mappings": [], "molecule_id": "P03023", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "4RZS", "doi": "10.1038/nmeth.3696", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4RZS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lac repressor engineered to bind sucralose, unliganded tetramer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEZ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Lactose operon repressor (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EDC", "evidence_id": "EV-PDB-3EDC-1", "mappings": [], "molecule_id": "P03023", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3EDC", "doi": "10.1002/prot.22284", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EDC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of a 1.6-hexanediol Bound Tetrameric Form of Escherichia coli Lac-repressor Refined to 2.1 Resolution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 41.85}, "construct": {"description": "Lactose operon repressor (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KEJ", "evidence_id": "EV-PDB-2KEJ-1", "mappings": [{"confidence": "medium", "justification": "Title names operator DNA and no inducer is bound.", "rule": "laci-operator-title", "state_id": "LacI-operator", "who": "rule:laci-operator-title"}], "molecule_id": "P03023", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KEJ", "doi": "10.1016/j.jmb.2009.05.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KEJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of a dimer of LAC repressor DNA-binding domain complexed to its natural operator O2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 41.85}, "construct": {"description": "Lactose operon repressor (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KEI", "evidence_id": "EV-PDB-2KEI-1", "mappings": [{"confidence": "medium", "justification": "Title names operator DNA and no inducer is bound.", "rule": "laci-operator-title", "state_id": "LacI-operator", "who": "rule:laci-operator-title"}], "molecule_id": "P03023", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KEI", "doi": "10.1016/j.jmb.2009.05.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KEI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Refined Solution Structure of a Dimer of LAC repressor DNA-Binding domain complexed to its natural operator O1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 41.85}, "construct": {"description": "LACTOSE OPERON REPRESSOR (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2BJC", "evidence_id": "EV-PDB-2BJC-1", "mappings": [], "molecule_id": "P03023", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2BJC", "doi": "10.1002/CBIC.200500049", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2BJC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of a protein-DNA complex of an altered specificity mutant of the lac repressor headpiece that mimics the gal repressor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EMC", "IPT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LAC REPRESSOR (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TLF", "evidence_id": "EV-PDB-1TLF-1", "mappings": [{"confidence": "high", "justification": "IPTG (IPT) bound.", "rule": "laci-iptg", "state_id": "LacI-IPTG", "who": "rule:laci-iptg"}], "molecule_id": "P03023", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1TLF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TLF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "UNPRECEDENTED QUATERNARY STRUCTURE OF E. COLI LAC REPRESSOR CORE TETRAMER: IMPLICATIONS FOR DNA LOOPING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.8, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Lactose operon repressor (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OSL", "evidence_id": "EV-PDB-1OSL-2", "mappings": [], "molecule_id": "P03023", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1OSL", "doi": "10.1126/science.1097064", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OSL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LAC REPRESSOR (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LQC", "evidence_id": "EV-PDB-1LQC-1", "mappings": [], "molecule_id": "P03023", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1LQC", "doi": "10.1006/jmbi.1996.0356", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LQC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "LAC REPRESSOR HEADPIECE (RESIDUES 1-56), NMR, 32 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lac Repressor (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LCD", "evidence_id": "EV-PDB-1LCD-3", "mappings": [{"confidence": "medium", "justification": "Title names operator DNA and no inducer is bound.", "rule": "laci-operator-title", "state_id": "LacI-operator", "who": "rule:laci-operator-title"}], "molecule_id": "P03023", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1LCD", "doi": "10.1006/jmbi.1993.1598", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LCD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lac Repressor (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LCC", "evidence_id": "EV-PDB-1LCC-3", "mappings": [{"confidence": "medium", "justification": "Title names operator DNA and no inducer is bound.", "rule": "laci-operator-title", "state_id": "LacI-operator", "who": "rule:laci-operator-title"}], "molecule_id": "P03023", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1LCC", "doi": "10.1006/jmbi.1993.1598", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LCC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "LAC REPRESSOR (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LBI", "evidence_id": "EV-PDB-1LBI-1", "mappings": [], "molecule_id": "P03023", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1LBI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LBI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LAC REPRESSOR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.65, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "GENERAL CONTROL PROTEIN GCN4 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FMH", "evidence_id": "EV-PDB-1FMH-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1FMH", "doi": "10.1021/bi001242e", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FMH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR SOLUTION STRUCTURE OF A DESIGNED HETERODIMERIC LEUCINE ZIPPER"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myosin heavy chain, striated muscle/General control protein GCN4 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3BAT", "evidence_id": "EV-PDB-3BAT-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3BAT", "doi": "10.1016/j.jmb.2007.11.071", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3BAT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (P21) form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IOD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myosin heavy chain, striated muscle/General control protein GCN4 chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3BAS", "evidence_id": "EV-PDB-3BAS-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3BAS", "doi": "10.1016/j.jmb.2007.11.071", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3BAS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "short alpha-tropomyosin,transcription factor GCN4 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3AZD", "evidence_id": "EV-PDB-3AZD-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.98}, "provenance": {"deposit_id": "3AZD", "doi": "10.1107/S090744491102645X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3AZD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of tropomyosin N-terminal fragment at 0.98A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GCN4 LEUCINE ZIPPER (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZTA", "evidence_id": "EV-PDB-2ZTA-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2ZTA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ZTA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY STRUCTURE OF THE GCN4 LEUCINE ZIPPER, A TWO-STRANDED, PARALLEL COILED COIL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Tropomyosin alpha-1 chain and General control protein GCN4 (chains I,J)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Z5I", "evidence_id": "EV-PDB-2Z5I-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2Z5I", "doi": "10.1073/pnas.0801950105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Z5I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the head-to-tail junction of tropomyosin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "General control protein GCN4 and Tropomyosin alpha-1 chain (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Z5I", "evidence_id": "EV-PDB-2Z5I-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2Z5I", "doi": "10.1073/pnas.0801950105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Z5I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the head-to-tail junction of tropomyosin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Tropomyosin alpha-1 chain and General control protein GCN4 (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Z5H", "evidence_id": "EV-PDB-2Z5H-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "2Z5H", "doi": "10.1073/pnas.0801950105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Z5H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the head-to-tail junction of tropomyosin complexed with a fragment of TnT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "General control protein GCN4 and Tropomyosin alpha-1 chain (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Z5H", "evidence_id": "EV-PDB-2Z5H-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "2Z5H", "doi": "10.1073/pnas.0801950105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Z5H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the head-to-tail junction of tropomyosin complexed with a fragment of TnT"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GENERAL CONTROL PROTEIN GCN4, PUTATIVE INNER MEMBRANE PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2YO2", "evidence_id": "EV-PDB-2YO2-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2YO2", "doi": "10.1073/PNAS.1211872110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2YO2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Salmonella enterica SadA 255-358 fused to GCN4 adaptors (SadAK12)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GENERAL CONTROL PROTEIN GCN4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WPY", "evidence_id": "EV-PDB-2WPY-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "2WPY", "doi": "10.1073/PNAS.0907256106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WPY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4 leucine zipper mutant with one VxxNxxx motif coordinating chloride"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GENERAL CONTROL PROTEIN GCN4, PROTEASOME-ACTIVATING NUCLEOTIDASE (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WG6", "evidence_id": "EV-PDB-2WG6-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "2WG6", "doi": "10.1016/J.MOLCEL.2009.04.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WG6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Proteasome-Activating Nucleotidase (PAN) N-domain (57-134) from Archaeoglobus fulgidus fused to GCN4, P61A Mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GENERAL CONTROL PROTEIN GCN4, PROTEASOME-ACTIVATING NUCLEOTIDASE (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WG5", "evidence_id": "EV-PDB-2WG5-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2WG5", "doi": "10.1016/J.MOLCEL.2009.04.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WG5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Proteasome-Activating Nucleotidase (PAN) N-domain (57-134) from Archaeoglobus fulgidus fused to GCN4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BIFUNCTIONAL TAIL PROTEIN, PIIGCN4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2VNL", "evidence_id": "EV-PDB-2VNL-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2VNL", "doi": "10.1107/S1399004714002685", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2VNL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MUTANT Y108Wdel OF THE HEADBINDING DOMAIN OF PHAGE P22 TAILSPIKE C- TERMINally fused to ISOLEUCINE ZIPPER pIIGCN4 (chimera II)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 34.85}, "construct": {"description": "Unconventional myosin-X, General control protein GCN4 fusion (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N9B", "evidence_id": "EV-PDB-2N9B-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N9B", "doi": "10.1016/j.bpj.2016.04.048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N9B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution NMR Structure of Antiparallel Myosin-10:GCN4 Tandem Coiled-Coil"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "General control protein GCN4 (chains B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LPB", "evidence_id": "EV-PDB-2LPB-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LPB", "doi": "10.1016/j.molcel.2011.11.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LPB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "IPA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control protein GCN4 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2IPZ", "evidence_id": "EV-PDB-2IPZ-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "2IPZ", "doi": "10.1021/bi061914m", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2IPZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A Parallel Coiled-Coil Tetramer with Offset Helices"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -263.15}, "construct": {"description": "Tropomyosin 1 alpha chain/General control protein GCN4 (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2G9J", "evidence_id": "EV-PDB-2G9J-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2G9J", "doi": "10.1016/j.jmb.2006.08.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2G9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Complex of TM1a(1-14)Zip with TM9a(251-284): a model for the polymerization domain (\"overlap region\") of tropomyosin, Northeast Structural Genomics Target OR9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "General control protein GCN4 and Tropomyosin 1 alpha chain (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2EFS", "evidence_id": "EV-PDB-2EFS-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2EFS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2EFS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the C-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 2.0 angstroms resolution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "PROTEIN (GCN4) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2DGC", "evidence_id": "EV-PDB-2DGC-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "2DGC", "doi": "10.1006/jmbi.1995.0645", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2DGC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4 BASIC DOMAIN, LEUCINE ZIPPER COMPLEXED WITH ATF/CREB SITE DNA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 10.5, "salt_mM": null, "temperature_c": -93.15}, "construct": {"description": "General control protein GCN4 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CCN", "evidence_id": "EV-PDB-2CCN-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "2CCN", "doi": "10.1021/bi060092q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CCN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "pLI E20C is antiparallel"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 10.0, "salt_mM": null, "temperature_c": -93.15}, "construct": {"description": "General control protein GCN4 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CCF", "evidence_id": "EV-PDB-2CCF-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2CCF", "doi": "10.1021/bi060092q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CCF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Antiparallel Configuration of pLI E20S"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 0.0, "salt_mM": null, "temperature_c": -93.15}, "construct": {"description": "General control protein GCN4 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CCE", "evidence_id": "EV-PDB-2CCE-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2CCE", "doi": "10.1021/bi060092q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CCE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Parallel Configuration of pLI E20S"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control protein GCN4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2B22", "evidence_id": "EV-PDB-2B22-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2B22", "doi": "10.1016/j.str.2005.10.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2B22"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control protein GCN4 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2B1F", "evidence_id": "EV-PDB-2B1F-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "2B1F", "doi": "10.1016/j.str.2005.10.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2B1F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GENERAL CONTROL PROTEIN GCN4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5APS", "evidence_id": "EV-PDB-5APS-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.37}, "provenance": {"deposit_id": "5APS", "doi": "10.7554/eLife.11861", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5APS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Sequence IENKKAD inserted between GCN4 adaptors - Structure A7"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VWH", "evidence_id": "EV-PDB-6VWH-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.26}, "provenance": {"deposit_id": "6VWH", "doi": "10.1016/j.str.2020.05.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VWI", "evidence_id": "EV-PDB-6VWI-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "6VWI", "doi": "10.1016/j.str.2020.05.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VWI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VWJ", "evidence_id": "EV-PDB-6VWJ-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.21}, "provenance": {"deposit_id": "6VWJ", "doi": "10.1016/j.str.2020.05.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Leg region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 Peptide with A16 (chains B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNE", "evidence_id": "EV-PDB-6XNE-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "6XNE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with p-methylphenylalanine residue at position 16 (me-F16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 Peptide with me-F16 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNE", "evidence_id": "EV-PDB-6XNE-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "6XNE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with p-methylphenylalanine residue at position 16 (me-F16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 peptide with A16 (chains B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNF", "evidence_id": "EV-PDB-6XNF-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6XNF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with Tetrafluoroiodophenylalanine residue at position 16 (TFI-F16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 peptide with TFI-F16 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNF", "evidence_id": "EV-PDB-6XNF-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6XNF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with Tetrafluoroiodophenylalanine residue at position 16 (TFI-F16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 Peptide with A16 (chains B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNL", "evidence_id": "EV-PDB-6XNL-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6XNL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with iodo-phenylalanine residue at position 16 (IPF-F16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 Peptide with IPF-F16 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNL", "evidence_id": "EV-PDB-6XNL-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6XNL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with iodo-phenylalanine residue at position 16 (IPF-F16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 peptide with Y16 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNM", "evidence_id": "EV-PDB-6XNM-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "6XNM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with tyrosine residue at position 16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4-p1 peptide with A16 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNM", "evidence_id": "EV-PDB-6XNM-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "6XNM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4-p1 Peptide Trimer with tyrosine residue at position 16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACE", "EDO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GCN4 isoform 1 (chains B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A4T", "evidence_id": "EV-PDB-7A4T-2", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.124}, "provenance": {"deposit_id": "7A4T", "doi": "10.1073/pnas.2021899118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A4T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the GCN coiled-coil in complex with nanobody Nb39"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control transcription factor GCN4,hypothetical protein OMM_04225 residues 244-274 from Candidatus Magnetoglobus multicellularis fused to GCN4 adaptors,General control transcription factor GCN4 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O9V", "evidence_id": "EV-PDB-7O9V-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "7O9V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O9V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "hypothetical protein OMM_04225 residues 244-274 from Candidatus Magnetoglobus multicellularis fused to GCN4 adaptors"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A,General control transcription factor GCN4 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAC", "evidence_id": "EV-PDB-7OAC-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "7OAC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A,General control transcription factor GCN4 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAD", "evidence_id": "EV-PDB-7OAD-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "7OAD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A,General control transcription factor GCN4 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAH", "evidence_id": "EV-PDB-7OAH-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.694}, "provenance": {"deposit_id": "7OAH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A,General control transcription factor GCN4 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAF", "evidence_id": "EV-PDB-7OAF-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "7OAF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form III"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors,General control transcription factor GCN4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAA", "evidence_id": "EV-PDB-7OAA-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "7OAA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "General control protein GCN4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O2F", "evidence_id": "EV-PDB-6O2F-1", "mappings": [], "molecule_id": "P03069", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "6O2F", "doi": "10.1021/acschembio.9b00432", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O2F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GCN4 with NPEG4 at position 18"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "UTP", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1R9S", "evidence_id": "EV-PDB-1R9S-3", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.25}, "provenance": {"deposit_id": "1R9S", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1R9S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1R9T", "evidence_id": "EV-PDB-1R9T-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "1R9T", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1R9T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWA", "evidence_id": "EV-PDB-1TWA-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "1TWA", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWC", "evidence_id": "EV-PDB-1TWC-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "1TWC", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with GTP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "UTP", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWF", "evidence_id": "EV-PDB-1TWF-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1TWF", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with UTP at 2.3 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CTP", "MN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWG", "evidence_id": "EV-PDB-1TWG-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "1TWG", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with CTP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TWH", "evidence_id": "EV-PDB-1TWH-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "1TWH", "doi": "10.1016/j.cell.2004.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II complexed with 2'dATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WCM", "evidence_id": "EV-PDB-1WCM-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "1WCM", "doi": "10.1074/JBC.M413038200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WCM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complete 12-Subunit RNA Polymerase II at 3.8 Angstrom"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y1V", "evidence_id": "EV-PDB-1Y1V-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "1Y1V", "doi": "10.1016/j.molcel.2004.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y1V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Refined RNA Polymerase II-TFIIS complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y1W", "evidence_id": "EV-PDB-1Y1W-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "1Y1W", "doi": "10.1016/j.molcel.2004.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y1W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complete RNA Polymerase II elongation complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/29RF", "evidence_id": "EV-PDB-29RF-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "29RF", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/29RF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-III"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JA8", "evidence_id": "EV-PDB-2JA8-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "2JA8", "doi": "10.1126/SCIENCE.1135400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JA8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CPD lesion containing RNA Polymerase II elongation complex D"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DNA-directed RNA polymerase (chains B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2L0I", "evidence_id": "EV-PDB-2L0I-2", "mappings": [], "molecule_id": "P04050", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2L0I", "doi": "10.1038/nsmb.1893", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2L0I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DUT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NVX", "evidence_id": "EV-PDB-2NVX-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "2NVX", "doi": "10.1016/j.cell.2006.11.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II largest subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y1Y", "evidence_id": "EV-PDB-1Y1Y-3", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "1Y1Y", "doi": "10.1016/j.molcel.2004.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y1Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA Polymerase II-TFIIS-DNA/RNA complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase subunit (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ML4", "evidence_id": "EV-PDB-7ML4-6", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7ML4", "doi": "10.1016/j.molcel.2021.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ML4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II initially transcribing complex (ITC)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NKX", "evidence_id": "EV-PDB-7NKX-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7NKX", "doi": "10.1038/s41594-021-00578-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NKX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II-Spt4/5-nucleosome-Chd1 structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NKY", "evidence_id": "EV-PDB-7NKY-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7NKY", "doi": "10.1038/s41594-021-00578-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NKY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RNA Polymerase II-Spt4/5-nucleosome-FACT structure"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O4L", "evidence_id": "EV-PDB-7O4L-9", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7O4L", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O4L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Yeast TFIIH in the expanded state within the pre-initiation complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UI9", "evidence_id": "EV-PDB-7UI9-21", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7UI9", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UI9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Core Mediator-PICearly (Copy A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A,z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UIF", "evidence_id": "EV-PDB-7UIF-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "7UIF", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UIF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-PIC Early (Core B)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UIG", "evidence_id": "EV-PDB-7UIG-17", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7UIG", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UIG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-PIC Early (Mediator A)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ALA", "ASP", "THR", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains Az,Bz)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UIO", "evidence_id": "EV-PDB-7UIO-22", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7UIO", "doi": "10.1016/j.molcel.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UIO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mediator-PIC Early (Composite Model)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CEN", "evidence_id": "EV-PDB-8CEN-9", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8CEN", "doi": "10.1073/pnas.2220542120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CEN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with core Mediator"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CEO", "evidence_id": "EV-PDB-8CEO-9", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8CEO", "doi": "10.1073/pnas.2220542120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CEO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JCH", "evidence_id": "EV-PDB-8JCH-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8JCH", "doi": "10.1038/s41586-024-07240-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JCH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 1 (Pol II Rat1-PTTC1)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVV", "evidence_id": "EV-PDB-8TVV-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8TVV", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of backtracked Pol II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVQ", "evidence_id": "EV-PDB-8TVQ-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "8TVQ", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TUG", "evidence_id": "EV-PDB-8TUG-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8TUG", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TUG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RAP", "evidence_id": "EV-PDB-8RAP-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "8RAP", "doi": "10.1038/s41594-024-01409-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RAP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Sen1-ADP.BeF3 bound RNA Polymerase II pre-termination complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RAM", "evidence_id": "EV-PDB-8RAM-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8RAM", "doi": "10.1038/s41594-024-01409-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RAM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Sen1 bound RNA Polymerase II pre-termination complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K5P", "evidence_id": "EV-PDB-8K5P-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8K5P", "doi": "10.1038/s41586-024-07240-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K5P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of yeast Rat1-bound Pol II pre-termination transcription complex 2 (Pol II Rat1-PTTC2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZSA", "evidence_id": "EV-PDB-7ZSA-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7ZSA", "doi": "10.1038/s41594-022-00865-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZSA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZS9", "evidence_id": "EV-PDB-7ZS9-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7ZS9", "doi": "10.1038/s41594-022-00865-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZS9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O4J", "evidence_id": "EV-PDB-7O4J-9", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7O4J", "doi": "10.1016/j.cell.2021.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O4J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Yeast RNA polymerase II transcription pre-initiation complex (consensus)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UQ2", "evidence_id": "EV-PDB-6UQ2-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "6UQ2", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UQ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dG in state 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["APC", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UPY", "evidence_id": "EV-PDB-6UPY-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6UPY", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UPY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UPX", "evidence_id": "EV-PDB-6UPX-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6UPX", "doi": "10.1073/pnas.1919904117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UPX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "PPV", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5D", "evidence_id": "EV-PDB-9N5D-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "9N5D", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, CMP added"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PDR", "evidence_id": "EV-PDB-9PDR-11", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "9PDR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of PIC-Med-SWI/SNF-Nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "PPV", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB4", "evidence_id": "EV-PDB-9SB4-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "9SB4", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-D"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "PPV", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB3", "evidence_id": "EV-PDB-9SB3-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "9SB3", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "PPV", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB2", "evidence_id": "EV-PDB-9SB2-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09}, "provenance": {"deposit_id": "9SB2", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "PPV", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB1", "evidence_id": "EV-PDB-9SB1-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9SB1", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "PPV", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB0", "evidence_id": "EV-PDB-9SB0-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "9SB0", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-VI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SAZ", "evidence_id": "EV-PDB-9SAZ-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31}, "provenance": {"deposit_id": "9SAZ", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SAZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex apo-state-II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SAY", "evidence_id": "EV-PDB-9SAY-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "9SAY", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SAY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex apo-state-I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DPO", "K", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RYB", "evidence_id": "EV-PDB-9RYB-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33}, "provenance": {"deposit_id": "9RYB", "doi": "10.1016/j.molcel.2026.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RYB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "K", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QEB", "evidence_id": "EV-PDB-9QEB-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26}, "provenance": {"deposit_id": "9QEB", "doi": "10.1016/j.molcel.2026.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of transcribing RNA polymerase II elongation complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["8GT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVX", "evidence_id": "EV-PDB-9PVX-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "9PVX", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dA at +1 site, 8-oxo-GTP bound in E-site."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "POP", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVW", "evidence_id": "EV-PDB-9PVW-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "9PVW", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dA at +1 site, 8-oxo-GMP added in Syn-conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["8GT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVV", "evidence_id": "EV-PDB-9PVV-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "9PVV", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dC at +1 site, 8-oxo-GTP bound in A-site."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVU", "evidence_id": "EV-PDB-9PVU-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31}, "provenance": {"deposit_id": "9PVU", "doi": "10.1073/pnas.2602266123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with dC at +1 site, 8-oxo-GMP added."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PDK", "evidence_id": "EV-PDB-9PDK-11", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9PDK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PDK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of closed form of PIC-Med-SWI/SNF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains AA,BA,MA,mA)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PDJ", "evidence_id": "EV-PDB-9PDJ-11", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9PDJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Composite map of open form of PIC-Med-SWI/SNF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PC8", "evidence_id": "EV-PDB-9PC8-7", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9PC8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PC8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Core Mediator of PIC-Med-SWI/SNF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PC7", "evidence_id": "EV-PDB-9PC7-15", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9PC7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PC7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Core Mediator of PIC-Med-SWI/SNF-Nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PBZ", "evidence_id": "EV-PDB-9PBZ-12", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9PBZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PBZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PolII/TFIIF of PIC-Med-SWI/SNF-Nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PBD", "evidence_id": "EV-PDB-9PBD-11", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9PBD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PBD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PolII/TFIIF of PIC-Med-SWI/SNF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5G", "evidence_id": "EV-PDB-9N5G-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15}, "provenance": {"deposit_id": "9N5G", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, ATP in both A- and E-site"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5F", "evidence_id": "EV-PDB-9N5F-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9N5F", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG in syn-conformation with added AMP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["APC", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5E", "evidence_id": "EV-PDB-9N5E-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "9N5E", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, AMPCPP in E-site"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2TM", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5C", "evidence_id": "EV-PDB-9N5C-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9N5C", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with 8-oxoG at +1 site, CMPCPP-bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9N5B", "evidence_id": "EV-PDB-9N5B-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9N5B", "doi": "10.1021/jacs.5c02687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9N5B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex containing 8-oxoG at +1 site, apo form"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K7F", "evidence_id": "EV-PDB-9K7F-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "9K7F", "doi": "10.1038/s41467-026-70612-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K7F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II elongation complex apo structure."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKR", "evidence_id": "EV-PDB-8UKR-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.78}, "provenance": {"deposit_id": "8UKR", "doi": "10.1021/jacs.3c14476", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKQ", "evidence_id": "EV-PDB-8UKQ-4", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8UKQ", "doi": "10.1021/jacs.3c14476", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNA polymerase II elongation complex with Fapy-dG lesion in apo state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "GOL", "MN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8U9X", "evidence_id": "EV-PDB-8U9X-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "8U9X", "doi": "10.1073/pnas.2318527121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8U9X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "GOL", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8U9R", "evidence_id": "EV-PDB-8U9R-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34}, "provenance": {"deposit_id": "8U9R", "doi": "10.1073/pnas.2318527121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8U9R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVY", "evidence_id": "EV-PDB-8TVY-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8TVY", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVX", "evidence_id": "EV-PDB-8TVX-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8TVX", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD-stalled Pol II (Conformation 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TVW", "evidence_id": "EV-PDB-8TVW-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8TVW", "doi": "10.1073/pnas.2314245121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TVW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CPD-stalled Pol II (conformation 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SB5", "evidence_id": "EV-PDB-9SB5-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "9SB5", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with NTP-state-II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBL", "evidence_id": "EV-PDB-9SBL-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.28}, "provenance": {"deposit_id": "9SBL", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBM", "evidence_id": "EV-PDB-9SBM-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.17}, "provenance": {"deposit_id": "9SBM", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBP", "evidence_id": "EV-PDB-9SBP-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "9SBP", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBQ", "evidence_id": "EV-PDB-9SBQ-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88}, "provenance": {"deposit_id": "9SBQ", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBR", "evidence_id": "EV-PDB-9SBR-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.96}, "provenance": {"deposit_id": "9SBR", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBS", "evidence_id": "EV-PDB-9SBS-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "9SBS", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBT", "evidence_id": "EV-PDB-9SBT-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "9SBT", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBU", "evidence_id": "EV-PDB-9SBU-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.83}, "provenance": {"deposit_id": "9SBU", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBW", "evidence_id": "EV-PDB-9SBW-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "9SBW", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBX", "evidence_id": "EV-PDB-9SBX-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "9SBX", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-13"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBY", "evidence_id": "EV-PDB-9SBY-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "9SBY", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-14"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBZ", "evidence_id": "EV-PDB-9SBZ-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "9SBZ", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-15"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC1", "evidence_id": "EV-PDB-9SC1-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "9SC1", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-17"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC4", "evidence_id": "EV-PDB-9SC4-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76}, "provenance": {"deposit_id": "9SC4", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-20"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8R", "evidence_id": "EV-PDB-9W8R-12", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "9W8R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a short control scaffold lacking cisplatin-ICL lesion."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8T", "evidence_id": "EV-PDB-9W8T-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "9W8T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a cisplatin-induced inter-strand crosslink lesion at the +7 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8U", "evidence_id": "EV-PDB-9W8U-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "9W8U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of pre-translocation state of yeast Pol II complexed with a cisplatin-induced inter-strand crosslink at the +2 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8V", "evidence_id": "EV-PDB-9W8V-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.23}, "provenance": {"deposit_id": "9W8V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of post-translocation state of yeast Pol II complexed with a cisplatin-induced inter-strand crosslink at the +2 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8Y", "evidence_id": "EV-PDB-9W8Y-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "9W8Y", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink at the + 3 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8Z", "evidence_id": "EV-PDB-9W8Z-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "9W8Z", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink at the + 2 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WQ7", "evidence_id": "EV-PDB-9WQ7-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "9WQ7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WQ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II-Elf1 complex containing a cisplatin-ICL lesion at +7 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WQ8", "evidence_id": "EV-PDB-9WQ8-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9WQ8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WQ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a longer scaffold containing a cisplatin-ICL lesion at +7 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WQ9", "evidence_id": "EV-PDB-9WQ9-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9WQ9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WQ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II in complex with a longer control scaffold lacking cisplatin-ICL lesion."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZPL", "evidence_id": "EV-PDB-9ZPL-9", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "9ZPL", "doi": "10.1016/j.jbc.2026.113389", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZPL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the complete Saccharomyces cerevisiae RNA polymerase II in open clamp conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZPK", "evidence_id": "EV-PDB-9ZPK-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31}, "provenance": {"deposit_id": "9ZPK", "doi": "10.1016/j.jbc.2026.113389", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZPK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the complete Saccharomyces cerevisiae RNA polymerase II in closed clamp conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8X", "evidence_id": "EV-PDB-9W8X-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "9W8X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of yeast Pol II complexed with a longer scaffold containing a cisplatin-induced inter-strand crosslink lesion at the +5 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CPT", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W8W", "evidence_id": "EV-PDB-9W8W-12", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "9W8W", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W8W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of backtracked yeast Pol II in complex with a cisplatin-induced inter-strand crosslink lesion at the +2 position."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "K", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SV6", "evidence_id": "EV-PDB-9SV6-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "9SV6", "doi": "10.1016/j.molcel.2026.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SV6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC3", "evidence_id": "EV-PDB-9SC3-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.68}, "provenance": {"deposit_id": "9SC3", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-19"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC2", "evidence_id": "EV-PDB-9SC2-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "9SC2", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-18"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SC0", "evidence_id": "EV-PDB-9SC0-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31}, "provenance": {"deposit_id": "9SC0", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SC0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBV", "evidence_id": "EV-PDB-9SBV-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "9SBV", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-11"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBO", "evidence_id": "EV-PDB-9SBO-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.97}, "provenance": {"deposit_id": "9SBO", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBN", "evidence_id": "EV-PDB-9SBN-1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "9SBN", "doi": "10.64898/2026.06.04.730248", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Yeast RNA polymerase II elongation complex with ATP frame-3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17044", "evidence_id": "EV-BMRB-17044", "mappings": [], "molecule_id": "P04050", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17044", "doi": "10.13018/BMR17044", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17044"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34041", "evidence_id": "EV-BMRB-34041", "mappings": [], "molecule_id": "P04050", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr34041", "doi": "10.13018/BMR34041", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34041"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Thr4 phosphorylated CTD peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34058", "evidence_id": "EV-BMRB-34058", "mappings": [], "molecule_id": "P04050", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr34058", "doi": "10.13018/BMR34058", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34058"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide"}
{"conditions": {"applied_force_pn": null, "buffer": "25 mM KH2PO4, 300 mM KCl, 10 mM BME", "environment": "in_vitro", "ions": [], "ligands": ["partner: Regulator of Ty1 transposition protein 103"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 21 nm.", "ph": 6.5, "salt_mM": null, "temperature_c": 4.0}, "construct": {"description": "DNA-directed RNA polymerase II subunit RPB1 with Regulator of Ty1 transposition protein 103", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDCZ2/", "evidence_id": "EV-SASBDB-SASDCZ2", "mappings": [], "molecule_id": "P04050", "observable": {"type": "radius_of_gyration", "uncertainty": 0.02, "unit": "nm", "value": 5.294}, "provenance": {"deposit_id": "SASDCZ2", "doi": "10.1073/pnas.1712450114", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDCZ2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the RNAPII CTDsome with Rtt103."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1549-1716; evidence: sodium dodecyl sulfate polyacrylamide gel electrophoresis evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/28497792", "evidence_id": "EV-DISPROT-DP02527r003", "mappings": [], "molecule_id": "P04050", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 168}, "provenance": {"deposit_id": "DP02527r003", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "gel_electrophoresis", "title": "DisProt DP02527: disorder, residues 1549-1716"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1456-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/28300169", "evidence_id": "EV-DISPROT-DP02527r004", "mappings": [], "molecule_id": "P04050", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 278}, "provenance": {"deposit_id": "DP02527r004", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1456-1733"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1446-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26123024", "evidence_id": "EV-DISPROT-DP02527r005", "mappings": [], "molecule_id": "P04050", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 288}, "provenance": {"deposit_id": "DP02527r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1446-1733"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1446-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/21798951", "evidence_id": "EV-DISPROT-DP02527r006", "mappings": [], "molecule_id": "P04050", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 288}, "provenance": {"deposit_id": "DP02527r006", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1446-1733"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1455-1733; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26186291", "evidence_id": "EV-DISPROT-DP02527r007", "mappings": [], "molecule_id": "P04050", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 279}, "provenance": {"deposit_id": "DP02527r007", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02527"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP02527: disorder, residues 1455-1733"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-1733", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P04050", "evidence_id": "EV-AFDB-AF-P04050-F1", "mappings": [], "molecule_id": "P04050", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 81.38}, "provenance": {"deposit_id": "AF-P04050-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P04050"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P04050-F1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Major prion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4N9O", "evidence_id": "EV-PDB-4N9O-1", "mappings": [], "molecule_id": "P04156", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4N9O", "doi": "10.1021/ja407527p", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4N9O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Probing the N-terminal beta-sheet conversion in the crystal structure of the human prion protein bound to a Nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Major prion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KML", "evidence_id": "EV-PDB-4KML-1", "mappings": [], "molecule_id": "P04156", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4KML", "doi": "10.1021/ja407527p", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KML"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Probing the N-terminal beta-sheet conversion in the crystal structure of the full-length human prion protein bound to a Nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Major prion protein (chains B,D,F,H,J,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4E1I", "evidence_id": "EV-PDB-4E1I-2", "mappings": [], "molecule_id": "P04156", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.03}, "provenance": {"deposit_id": "4E1I", "doi": "10.1021/ja403001q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4E1I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment of human prion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Major prion protein (chains A,C,E,G,I,K)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4E1I", "evidence_id": "EV-PDB-4E1I-1", "mappings": [], "molecule_id": "P04156", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.03}, "provenance": {"deposit_id": "4E1I", "doi": "10.1021/ja403001q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4E1I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment of human prion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "FE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Major prion protein (chains B,D,F,H,J,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4E1H", "evidence_id": "EV-PDB-4E1H-2", "mappings": [], "molecule_id": "P04156", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "4E1H", "doi": "10.1021/ja403001q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4E1H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment of human prion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "FE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Major prion protein (chains A,C,E,G,I,K)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4E1H", "evidence_id": "EV-PDB-4E1H-1", "mappings": [], "molecule_id": "P04156", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "4E1H", "doi": "10.1021/ja403001q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4E1H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment of human prion protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Major prion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HAK", "evidence_id": "EV-PDB-3HAK-1", "mappings": [], "molecule_id": "P04156", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3HAK", "doi": "10.1038/emboj.2009.333", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HAK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human prion protein variant V129"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": 25.85}, "construct": {"description": "Major prion protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M8T", "evidence_id": "EV-PDB-2M8T-1", "mappings": [], "molecule_id": "P04156", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M8T", "doi": "10.1016/j.celrep.2013.06.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M8T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution NMR structure of the V209M variant of the human prion protein (residues 90-231)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Major prion protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LSB", "evidence_id": "EV-PDB-2LSB-1", "mappings": [], "molecule_id": "P04156", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LSB", "doi": "10.1042/BJ20111940", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LSB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution-state NMR structure of the human prion protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 23-124; evidence: nuclear magnetic resonance evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/30401430", "evidence_id": "EV-DISPROT-DP00466r006", "mappings": [], "molecule_id": "P04156", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 102}, "provenance": {"deposit_id": "DP00466r006", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP00466"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP00466: disorder to order, residues 23-124"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "von Willebrand factor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PPX", "evidence_id": "EV-PDB-3PPX-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.91}, "provenance": {"deposit_id": "3PPX", "doi": "10.1182/blood-2010-11-321596", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PPX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains A,B,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PMV", "evidence_id": "EV-PDB-7PMV-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7PMV", "doi": "10.1073/pnas.2116790119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PMV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF Tubules of D1D2D'D3 domains"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D3D", "evidence_id": "EV-PDB-8D3D-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8D3D", "doi": "10.1182/blood.2022016467", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D3D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF tubule derived from dimeric D1-A1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D3C", "evidence_id": "EV-PDB-8D3C-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8D3C", "doi": "10.1182/blood.2022016467", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D3C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF tubule derived from monomeric D1-A1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZWH", "evidence_id": "EV-PDB-7ZWH-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7ZWH", "doi": "10.1182/blood.2022017153", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF Tubules of D1D2 and D'D3A1 domains"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZWH", "evidence_id": "EV-PDB-7ZWH-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7ZWH", "doi": "10.1182/blood.2022017153", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF Tubules of D1D2 and D'D3A1 domains"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains C,D,S,T,U,V,W,X,Y,Z,a,b,c,d,e,f)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WQT", "evidence_id": "EV-PDB-7WQT-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7WQT", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WQT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand antigen 2 (chains A,B,E,F,G,H,I,J,K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WQT", "evidence_id": "EV-PDB-7WQT-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7WQT", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WQT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains C,D,F,H,J,L,N,P,R,T,V,X,Z,b)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPS", "evidence_id": "EV-PDB-7WPS-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.32}, "provenance": {"deposit_id": "7WPS", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (7 units)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand antigen 2 (chains A,B,E,G,I,K,M,O,Q,S,U,W,Y,a)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPS", "evidence_id": "EV-PDB-7WPS-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.32}, "provenance": {"deposit_id": "7WPS", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (7 units)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains C,D,S,T,U,V,W,X,Y,Z,a,b,c,d,e,f)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPR", "evidence_id": "EV-PDB-7WPR-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.39}, "provenance": {"deposit_id": "7WPR", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand antigen 2 (chains A,B,E,F,G,H,I,J,K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPR", "evidence_id": "EV-PDB-7WPR-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.39}, "provenance": {"deposit_id": "7WPR", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains C,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPQ", "evidence_id": "EV-PDB-7WPQ-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.267}, "provenance": {"deposit_id": "7WPQ", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand antigen 2 (chains A,B,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPQ", "evidence_id": "EV-PDB-7WPQ-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.267}, "provenance": {"deposit_id": "7WPQ", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPP", "evidence_id": "EV-PDB-7WPP-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7WPP", "doi": "10.1182/blood.2021014729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 2.85 angstron resolution (1 unit)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand antigen 2 (chains A,B,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WN6", "evidence_id": "EV-PDB-7WN6-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7WN6", "doi": "10.1038/s41421-022-00378-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer (R1136M/E1143M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WN4", "evidence_id": "EV-PDB-7WN4-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WN4", "doi": "10.1038/s41421-022-00378-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WN4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer (wild type) complexed with D1D2 at 3.4 angstron resolution (1 unit)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand antigen 2 (chains E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WN4", "evidence_id": "EV-PDB-7WN4-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WN4", "doi": "10.1038/s41421-022-00378-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WN4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer (wild type) complexed with D1D2 at 3.4 angstron resolution (1 unit)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains C,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WN3", "evidence_id": "EV-PDB-7WN3-2", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7WN3", "doi": "10.1038/s41421-022-00378-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WN3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer (2M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand antigen 2 (chains A,B,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WN3", "evidence_id": "EV-PDB-7WN3-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7WN3", "doi": "10.1038/s41421-022-00378-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WN3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of VWF D'D3 dimer (2M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "von Willebrand factor (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PNF", "evidence_id": "EV-PDB-7PNF-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.35}, "provenance": {"deposit_id": "7PNF", "doi": "10.1073/pnas.2116790119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PNF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VWF Tubules of D1D2D'D3 domains"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "von Willebrand factor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EOW", "evidence_id": "EV-PDB-7EOW-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "7EOW", "doi": "10.1016/j.bbrc.2021.06.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-resolution structure of vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "von Willebrand factor (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6FWN", "evidence_id": "EV-PDB-6FWN-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6FWN", "doi": "10.1182/blood-2018-04-843615", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6FWN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "von Willebrand Factor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HXQ", "evidence_id": "EV-PDB-3HXQ-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.694}, "provenance": {"deposit_id": "3HXQ", "doi": "10.1016/j.str.2009.09.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HXQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "von Willebrand Factor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1M10", "evidence_id": "EV-PDB-1M10-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "1M10", "doi": "10.1126/science.107355", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1M10"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -162.15}, "construct": {"description": "von Willebrand factor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IJK", "evidence_id": "EV-PDB-1IJK-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1IJK", "doi": "10.1016/S0969-2126(02)00787-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IJK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The von Willebrand Factor mutant (I546V) A1 domain-botrocetin Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -177.15}, "construct": {"description": "von Willebrand factor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IJB", "evidence_id": "EV-PDB-1IJB-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1IJB", "doi": "10.1016/S0969-2126(02)00787-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IJB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The von Willebrand Factor mutant (I546V) A1 domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "VON WILLEBRAND FACTOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FNS", "evidence_id": "EV-PDB-1FNS-3", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1FNS", "doi": "10.1038/79639", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FNS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR (VWF) A1 DOMAIN I546V MUTANT IN COMPLEX WITH THE FUNCTION BLOCKING FAB NMC4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAC", "NAG", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "VON WILLEBRAND FACTOR (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FE8", "evidence_id": "EV-PDB-1FE8-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.03}, "provenance": {"deposit_id": "1FE8", "doi": "10.1074/jbc.M006548200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "A1 DOMAIN OF VON WILLEBRAND FACTOR (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AUQ", "evidence_id": "EV-PDB-1AUQ-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1AUQ", "doi": "10.1074/jbc.273.17.10396", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AUQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A1 DOMAIN OF VON WILLEBRAND FACTOR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "VON WILLEBRAND FACTOR (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ATZ", "evidence_id": "EV-PDB-1ATZ-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1ATZ", "doi": "10.1016/S0969-2126(97)00266-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ATZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN VON WILLEBRAND FACTOR A3 DOMAIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "VON WILLEBRAND FACTOR (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AO3", "evidence_id": "EV-PDB-1AO3-1", "mappings": [], "molecule_id": "P04275", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1AO3", "doi": "10.1074/jbc.272.40.25162", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AO3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A3 DOMAIN OF VON WILLEBRAND FACTOR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34243", "evidence_id": "EV-BMRB-34243", "mappings": [], "molecule_id": "P04275", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr34243", "doi": "10.13018/BMR34243", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34243"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34648", "evidence_id": "EV-BMRB-34648", "mappings": [], "molecule_id": "P04275", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr34648", "doi": "10.13018/BMR34648", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34648"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR solution structure of the C6 domain of von Willebrand Factor"}
{"conditions": {"applied_force_pn": null, "buffer": "10 mM HEPES, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 14 nm.", "ph": 7.4, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDKT8/", "evidence_id": "EV-SASBDB-SASDKT8", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.03, "unit": "nm", "value": 3.08}, "provenance": {"deposit_id": "SASDKT8", "doi": "10.1016/j.jmb.2021.166954", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDKT8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "An Integrative Structural Biology Analysis of Von Willebrand Factor Binding and Processing by ADAMTS-13 in Solution."}
{"conditions": {"applied_force_pn": null, "buffer": "10 mM HEPES, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 14.93 nm.", "ph": 7.4, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDKU8/", "evidence_id": "EV-SASBDB-SASDKU8", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.024, "unit": "nm", "value": 3.04}, "provenance": {"deposit_id": "SASDKU8", "doi": "10.1016/j.jmb.2021.166954", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDKU8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "An Integrative Structural Biology Analysis of Von Willebrand Factor Binding and Processing by ADAMTS-13 in Solution."}
{"conditions": {"applied_force_pn": null, "buffer": "10 mM HEPES, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: A disintegrin and metalloproteinase with thrombospondin motifs 13"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16.3 nm.", "ph": 7.4, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor with A disintegrin and metalloproteinase with thrombospondin motifs 13", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDKV8/", "evidence_id": "EV-SASBDB-SASDKV8", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.014, "unit": "nm", "value": 4.38}, "provenance": {"deposit_id": "SASDKV8", "doi": "10.1016/j.jmb.2021.166954", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDKV8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "An Integrative Structural Biology Analysis of Von Willebrand Factor Binding and Processing by ADAMTS-13 in Solution."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris-HCl, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.61 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor C6 domain wild type", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLQ9/", "evidence_id": "EV-SASBDB-SASDLQ9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.006, "unit": "nm", "value": 1.749}, "provenance": {"deposit_id": "SASDLQ9", "doi": "10.1016/j.jsb.2022.107923", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLQ9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris-HCl, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.7 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor C6 domain G2705K mutant", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLR9/", "evidence_id": "EV-SASBDB-SASDLR9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.01, "unit": "nm", "value": 1.8}, "provenance": {"deposit_id": "SASDLR9", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLR9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 15 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "von Willebrand factor C6-CK wildtype", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLS9/", "evidence_id": "EV-SASBDB-SASDLS9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.023, "unit": "nm", "value": 3.27}, "provenance": {"deposit_id": "SASDLS9", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLS9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16.5 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "von Willebrand factor C6-CK G2705R", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLT9/", "evidence_id": "EV-SASBDB-SASDLT9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.012, "unit": "nm", "value": 3.453}, "provenance": {"deposit_id": "SASDLT9", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLT9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "von Willebrand factor C6-CK G2705K", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLU9/", "evidence_id": "EV-SASBDB-SASDLU9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.012, "unit": "nm", "value": 3.515}, "provenance": {"deposit_id": "SASDLU9", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLU9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 150 mM NaCl, 1 mM CaCl2, 1 mM MgCl2", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 34.8 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor D4N-CK wildtype", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLV9/", "evidence_id": "EV-SASBDB-SASDLV9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.019, "unit": "nm", "value": 7.808}, "provenance": {"deposit_id": "SASDLV9", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLV9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 150 mM NaCl, 1 mM CaCl2, 1 mM MgCl2", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 68.54 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor D4N-CK G2705R", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLW9/", "evidence_id": "EV-SASBDB-SASDLW9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.076, "unit": "nm", "value": 11.356}, "provenance": {"deposit_id": "SASDLW9", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLW9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 150 mM NaCl, 1 mM CaCl2, 1 mM MgCl2", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 52 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "von Willebrand factor D4N-CK G2705K", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDLX9/", "evidence_id": "EV-SASBDB-SASDLX9", "mappings": [], "molecule_id": "P04275", "observable": {"type": "radius_of_gyration", "uncertainty": 0.053, "unit": "nm", "value": 9.812}, "provenance": {"deposit_id": "SASDLX9", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDLX9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structure and dynamics of the von Willebrand Factor C6 domain"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "P53 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AIE", "evidence_id": "EV-PDB-1AIE-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1AIE", "doi": "10.1107/S0907444997006550", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AIE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "P53 TETRAMERIZATION DOMAIN CRYSTAL STRUCTURE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "CELLULAR TUMOR ANTIGEN P53 (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HS5", "evidence_id": "EV-PDB-1HS5-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1HS5", "doi": "10.1006/jmbi.2001.4450", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HS5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR SOLUTION STRUCTURE OF DESIGNED P53 DIMER"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TUMOR SUPPRESSOR P53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PES", "evidence_id": "EV-PDB-1PES-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1PES", "doi": "10.1038/nsb1294-877", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR SOLUTION STRUCTURE OF THE TETRAMERIC MINIMUM TRANSFORMING DOMAIN OF P53"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TUMOR SUPPRESSOR P53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PET", "evidence_id": "EV-PDB-1PET-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1PET", "doi": "10.1038/nsb1294-877", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PET"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR SOLUTION STRUCTURE OF THE TETRAMERIC MINIMUM TRANSFORMING DOMAIN OF P53"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TUMOR SUPPRESSOR P53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SAE", "evidence_id": "EV-PDB-1SAE-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1SAE", "doi": "10.1038/nsb0495-321", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SAE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "HIGH RESOLUTION SOLUTION NMR STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR (SAC STRUCTURES)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TUMOR SUPPRESSOR P53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SAF", "evidence_id": "EV-PDB-1SAF-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1SAF", "doi": "10.1038/nsb0495-321", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SAF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "HIGH RESOLUTION SOLUTION NMR STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR (SAD STRUCTURES)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TUMOR SUPPRESSOR P53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SAK", "evidence_id": "EV-PDB-1SAK-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1SAK", "doi": "10.1038/nsb0495-321", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SAK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "HIGH RESOLUTION SOLUTION NMR STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR (SAC STRUCTURES)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TUMOR SUPPRESSOR P53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SAL", "evidence_id": "EV-PDB-1SAL-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1SAL", "doi": "10.1038/nsb0495-321", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SAL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "HIGH RESOLUTION SOLUTION NMR STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR (SAD STRUCTURES)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "PROTEIN (P53 TUMOR SUPPRESSOR) (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TSR", "evidence_id": "EV-PDB-1TSR-3", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1TSR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TSR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "P53 CORE DOMAIN IN COMPLEX WITH DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PROTEIN (P53 TUMOR SUPPRESSOR ) (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TUP", "evidence_id": "EV-PDB-1TUP-3", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1TUP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TUP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CELLULAR TUMOR ANTIGEN P53 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UOL", "evidence_id": "EV-PDB-1UOL-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1UOL", "doi": "10.1074/JBC.M309732200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UOL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human p53 core domain mutant M133L/V203A/N239Y/N268D at 1.9 A resolution."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "P53 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YCQ", "evidence_id": "EV-PDB-1YCQ-2", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1YCQ", "doi": "10.1126/science.274.5289.948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YCQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "P53 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YCR", "evidence_id": "EV-PDB-1YCR-2", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1YCR", "doi": "10.1126/science.274.5289.948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YCR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "P53 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YCS", "evidence_id": "EV-PDB-1YCS-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1YCS", "doi": "10.1126/science.274.5289.1001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YCS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "P53-53BP2 COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cellular tumor antigen p53 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/21EX", "evidence_id": "EV-PDB-21EX-3", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.021}, "provenance": {"deposit_id": "21EX", "doi": "10.1107/S2059798326007564", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/21EX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Wild tipe p53WT-HLA-A2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cellular tumor antigen p53 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ADY", "evidence_id": "EV-PDB-2ADY-2", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "2ADY", "doi": "10.1016/j.molcel.2006.05.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ADY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural Basis of DNA Recognition by p53 Tetramers (complex IV)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cellular tumor antigen p53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2AHI", "evidence_id": "EV-PDB-2AHI-2", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "2AHI", "doi": "10.1016/j.molcel.2006.05.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2AHI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural Basis of DNA Recognition by p53 Tetramers (complex III)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cellular tumor antigen p53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ATA", "evidence_id": "EV-PDB-2ATA-2", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "2ATA", "doi": "10.1016/j.molcel.2006.05.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ATA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural Basis of DNA Recognition by p53 Tetramers (complex II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.9, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cellular tumor antigen p53 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2B3G", "evidence_id": "EV-PDB-2B3G-2", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "2B3G", "doi": "10.1073/pnas.0504614102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2B3G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "p53N (fragment 33-60) bound to RPA70N"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CELLULAR TUMOR ANTIGEN P53 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2BIM", "evidence_id": "EV-PDB-2BIM-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.98}, "provenance": {"deposit_id": "2BIM", "doi": "10.1074/JBC.M500179200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2BIM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "human p53 core domain mutant M133L-V203A-N239Y-N268D-R273H"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -188.15}, "construct": {"description": "Cellular tumor antigen p53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TS8", "evidence_id": "EV-PDB-3TS8-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "3TS8", "doi": "10.1158/1541-7786.MCR-11-0351", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TS8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a multidomain human p53 tetramer bound to the natural CDKN1A(p21) p53-response element"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -188.15}, "construct": {"description": "Cellular tumor antigen p53 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MZR", "evidence_id": "EV-PDB-4MZR-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "4MZR", "doi": "10.1016/j.jmb.2013.12.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MZR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a polypeptide p53 mutant bound to DNA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cellular tumor antigen p53 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5BUA", "evidence_id": "EV-PDB-5BUA-1", "mappings": [], "molecule_id": "P04637", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.812}, "provenance": {"deposit_id": "5BUA", "doi": "10.1016/j.jmb.2016.06.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5BUA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Lysine 120-acetylated P53 DNA binding domain in a complex with DNA."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 19.95}, "construct": {"description": "Major prion protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KFM", "evidence_id": "EV-PDB-2KFM-1", "mappings": [], "molecule_id": "P04925", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KFM", "doi": "10.1016/j.jmb.2009.04.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KFM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Mouse Prion Protein (121-231) with Mutations Y225A and Y226A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Major prion protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y16", "evidence_id": "EV-PDB-1Y16-1", "mappings": [], "molecule_id": "P04925", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1Y16", "doi": "10.1073/pnas.0409008102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y16"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "mouse prion protein with mutations S170N and N174T"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 5.0, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=15053", "evidence_id": "EV-BMRB-15053", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr15053", "doi": "10.13018/BMR15053", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=15053"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "HPRP-173-195 SOLUTION STRUCTURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 5.0, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=15054", "evidence_id": "EV-BMRB-15054", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr15054", "doi": "10.13018/BMR15054", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=15054"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "HPRP180-195 STRUCTURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 25.05}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=15845", "evidence_id": "EV-BMRB-15845", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr15845", "doi": "10.13018/BMR15845", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=15845"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Mouse Prion Protein (121-231) with Mutation S170N"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 19.95}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=16184", "evidence_id": "EV-BMRB-16184", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr16184", "doi": "10.13018/BMR16184", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=16184"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Mouse Prion Protein (121-231) with Mutations Y225A and Y226A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 19.95}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=16185", "evidence_id": "EV-BMRB-16185", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr16185", "doi": "10.13018/BMR16185", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=16185"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Mouse Prion Protein (121-231) with Mutation V166A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=16722", "evidence_id": "EV-BMRB-16722", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr16722", "doi": "10.13018/BMR16722", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=16722"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "mPrP_D167S"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=16723", "evidence_id": "EV-BMRB-16723", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr16723", "doi": "10.13018/BMR16723", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=16723"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "mPrP_D1567D_N173K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 20.05}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17081", "evidence_id": "EV-BMRB-17081", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17081", "doi": "10.13018/BMR17081", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17081"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Mouse Prion Protein (121-231) with mutation Y169G"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 20.05}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17082", "evidence_id": "EV-BMRB-17082", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17082", "doi": "10.13018/BMR17082", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17082"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Mouse Prion Protein (121-231) with mutation F175A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 20.05}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17084", "evidence_id": "EV-BMRB-17084", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17084", "doi": "10.13018/BMR17084", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17084"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR structure of mouse PrP fragment 121-231 at 20 C."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 37.05}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17174", "evidence_id": "EV-BMRB-17174", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17174", "doi": "10.13018/BMR17174", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17174"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "MOUSE PRION PROTEIN FRAGMENT 121-231 AT 37 C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 20.05}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17213", "evidence_id": "EV-BMRB-17213", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17213", "doi": "10.13018/BMR17213", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17213"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Mouse prion protein (121-231) with the mutation Y169A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 2.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17758", "evidence_id": "EV-BMRB-17758", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17758", "doi": "10.13018/BMR17758", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17758"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H and 13C Chemical Shift Assignments of murine prion protein (residues 121-232) in its oxidized state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5197", "evidence_id": "EV-BMRB-5197", "mappings": [], "molecule_id": "P04925", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5197", "doi": "10.13018/BMR5197", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5197"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H and 13CA chemical shift assignments of the polypeptide mPrP(143-158)"}
{"conditions": {"applied_force_pn": null, "buffer": "sodium acetate buffer (20 mM sodium acetate, pH 5.1; 150 mM NaCl)", "environment": "in_vitro", "ions": [], "ligands": ["partner: P-Clone Fab, Chimera"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 14.5 nm.", "ph": 5.1, "salt_mM": null, "temperature_c": 9.8}, "construct": {"description": "Major prion protein with P-Clone Fab, Chimera", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDCJ2/", "evidence_id": "EV-SASBDB-SASDCJ2", "mappings": [], "molecule_id": "P04925", "observable": {"type": "radius_of_gyration", "uncertainty": 0.02, "unit": "nm", "value": 3.92}, "provenance": {"deposit_id": "SASDCJ2", "doi": "10.1016/j.bpj.2015.06.065", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDCJ2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ALZHEIMER'S DISEASE AMYLOID A4 PROTEIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AAP", "evidence_id": "EV-PDB-1AAP-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1AAP", "doi": "10.1021/bi00495a002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AAP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AMYLOID BETA PEPTIDE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QCM", "evidence_id": "EV-PDB-1QCM-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1QCM", "doi": "10.1021/bi961598j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QCM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "AMYLOID BETA PEPTIDE (25-35), NMR, 20 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TAW", "evidence_id": "EV-PDB-1TAW-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1TAW", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TAW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BOVINE TRYPSIN COMPLEXED TO APPI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Amyloid beta A4 protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TKN", "evidence_id": "EV-PDB-1TKN-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1TKN", "doi": "10.1021/bi049041o", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TKN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of CAPPD*, an independently folded extracellular domain of human Amyloid-beta Precursor Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "13-MER PEPTIDE (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1X11", "evidence_id": "EV-PDB-1X11-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1X11", "doi": "10.1093/emboj/16.20.6141", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1X11"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X11 PTB DOMAIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Alzheimer's disease amyloid (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Z0Q", "evidence_id": "EV-PDB-1Z0Q-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1Z0Q", "doi": "10.1002/cbic.200500223", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Z0Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Aqueous Solution Structure of the Alzheimer's Disease Abeta Peptide (1-42)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACM", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -160.15}, "construct": {"description": "abeta 1-8 peptide (chains P,Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2IPU", "evidence_id": "EV-PDB-2IPU-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "2IPU", "doi": "10.1073/pnas.0705888104", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2IPU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PFA1 Fab fragment complexed with Abeta 1-8 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.3, "salt_mM": null, "temperature_c": -258.15}, "construct": {"description": "Beta-amyloid protein 40 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LFM", "evidence_id": "EV-PDB-2LFM-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LFM", "doi": "10.1016/j.bbrc.2011.06.133", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LFM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "A partially folded structure of amyloid-beta(1 40) in an aqueous environment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Beta-amyloid protein 40 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LMQ", "evidence_id": "EV-PDB-2LMQ-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LMQ", "doi": "10.1073/pnas.0806270105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LMQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Negative Stagger"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.15, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "11-mer peptide from Amyloid beta A4 protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QYT", "evidence_id": "EV-PDB-1QYT-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1QYT", "doi": "10.1021/jm040773o", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QYT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of fragment (25-35) of beta amyloid peptide in SDS micellar solution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "11-mer peptide from Amyloid beta A4 protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QXC", "evidence_id": "EV-PDB-1QXC-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1QXC", "doi": "10.1021/jm040773o", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of the fragment 25-35 of beta amyloid peptide in 20/80 v:v hexafluoroisopropanol/water mixture"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "11-mer peptide from Amyloid beta A4 protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QWP", "evidence_id": "EV-PDB-1QWP-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1QWP", "doi": "10.1021/jm040773o", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QWP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR analysis of 25-35 fragment of beta amyloid peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "Amyloid beta A4 protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OWT", "evidence_id": "EV-PDB-1OWT-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1OWT", "doi": "10.1074/jbc.M300629200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OWT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of the Alzheimer's disease amyloid precursor protein copper binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "AMYLOID A4 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MWP", "evidence_id": "EV-PDB-1MWP-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1MWP", "doi": "10.1038/7562", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MWP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Alzheimer's disease amyloid (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IYT", "evidence_id": "EV-PDB-1IYT-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1IYT", "doi": "10.1046/j.1432-1033.2002.03271.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IYT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the Alzheimer's disease amyloid beta-peptide (1-42)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "A-BETA AMYLOID (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HZ3", "evidence_id": "EV-PDB-1HZ3-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1HZ3", "doi": "10.1006/jsbi.2000.4288", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HZ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "ALZHEIMER'S DISEASE AMYLOID-BETA PEPTIDE (RESIDUES 10-35)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR (chains D,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CA0", "evidence_id": "EV-PDB-1CA0-4", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1CA0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CA0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BOVINE CHYMOTRYPSIN COMPLEXED TO APPI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AMYLOID BETA-PROTEIN PRECURSOR INHIBITOR DOMAIN (APPI) (chains I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BRC", "evidence_id": "EV-PDB-1BRC-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1BRC", "doi": "10.1006/jmbi.1993.1211", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BRC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.8, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "AMYLOID BETA-PEPTIDE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BJC", "evidence_id": "EV-PDB-1BJC-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BJC", "doi": "10.1006/jsbi.2000.4267", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BJC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION NMR STRUCTURE OF AMYLOID BETA[F16], RESIDUES 1-28, 15 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 22.85}, "construct": {"description": "AMYLOID BETA-PEPTIDE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BJB", "evidence_id": "EV-PDB-1BJB-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BJB", "doi": "10.1006/jsbi.2000.4267", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BJB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION NMR STRUCTURE OF AMYLOID BETA[E16], RESIDUES 1-28, 14 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.3, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "AMYLOID BETA-PEPTIDE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BA6", "evidence_id": "EV-PDB-1BA6-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BA6", "doi": "10.1021/bi9810757", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BA6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF THE METHIONINE-OXIDIZED AMYLOID BETA-PEPTIDE (1-40). DOES OXIDATION AFFECT CONFORMATIONAL SWITCHING? NMR, 10 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.1, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "AMYLOID BETA-PEPTIDE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BA4", "evidence_id": "EV-PDB-1BA4-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BA4", "doi": "10.1021/bi972979f", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BA4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THE SOLUTION STRUCTURE OF AMYLOID BETA-PEPTIDE (1-40) IN A WATER-MICELLE ENVIRONMENT. IS THE MEMBRANE-SPANNING DOMAIN WHERE WE THINK IT IS? NMR, 10 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AMYLOID A4 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AML", "evidence_id": "EV-PDB-1AML-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1AML", "doi": "10.1111/j.1432-1033.1995.293_1.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AML"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THE ALZHEIMER`S DISEASE AMYLOID A4 PEPTIDE (RESIDUES 1-40)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AMYLOID BETA-PEPTIDE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AMC", "evidence_id": "EV-PDB-1AMC-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1AMC", "doi": "10.1021/bi00191a006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AMC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF RESIDUES 1-28 OF THE AMYLOID BETA-PEPTIDE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AMYLOID BETA-PEPTIDE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AMB", "evidence_id": "EV-PDB-1AMB-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1AMB", "doi": "10.1021/bi00191a006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AMB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF RESIDUES 1-28 OF THE AMYLOID BETA-PEPTIDE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "RT-Ab40(C1) (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/11EP", "evidence_id": "EV-PDB-11EP-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "11EP", "doi": "10.64898/2026.04.10.717728", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/11EP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Rapidly twisting Amyloid-beta 40 fibril , RT-Ab40(C1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "RT-Ab40(C2) (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/11EO", "evidence_id": "EV-PDB-11EO-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.73}, "provenance": {"deposit_id": "11EO", "doi": "10.64898/2026.04.10.717728", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/11EO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Rapidly twisting Amyloid-beta 40 fibril , RT-Ab40(C2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "RT-Ab40(2_1) (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/11EN", "evidence_id": "EV-PDB-11EN-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "11EN", "doi": "10.64898/2026.04.10.717728", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/11EN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Rapidly twisting Amyloid-beta 40 fibril , RT-Ab40(2_1)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3U0T", "evidence_id": "EV-PDB-3U0T-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "3U0T", "doi": "10.1016/j.jmb.2011.11.047", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3U0T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fab-antibody complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "AICD peptide E683V variant (chains L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MXY", "evidence_id": "EV-PDB-3MXY-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3MXY", "doi": "10.1016/j.jmb.2011.09.046", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structures of Grb2-SH2 Domain and AICD peptide Complexes Reveal a Conformational Switch and Their Functional Implications."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "New antigen receptor variable domain,P3(40) peptide from Amyloid beta A4 protein,New antigen receptor variable domain (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MOQ", "evidence_id": "EV-PDB-3MOQ-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.054}, "provenance": {"deposit_id": "3MOQ", "doi": "10.1523/JNEUROSCI.4259-10.2011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MOQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Amyloid beta(18-41) peptide fusion with new antigen receptor variable domain from sharks"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid Beta Peptide (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3BKJ", "evidence_id": "EV-PDB-3BKJ-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.59}, "provenance": {"deposit_id": "3BKJ", "doi": "10.1016/j.jmb.2007.12.036", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3BKJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid Beta Peptide (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3BAE", "evidence_id": "EV-PDB-3BAE-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.593}, "provenance": {"deposit_id": "3BAE", "doi": "10.1016/j.jmb.2007.12.036", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3BAE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid beta A4 protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3AYU", "evidence_id": "EV-PDB-3AYU-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3AYU", "doi": "10.1074/jbc.M111.264176", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3AYU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MMP-2 active site mutant in complex with APP-drived decapeptide inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta protein 40,HLA class II histocompatibility antigen, DRB1 beta chain (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/31VO", "evidence_id": "EV-PDB-31VO-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "31VO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/31VO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of amyloid beta 1-15 fragment bound to HLA-DR1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "AMYLOID BETA A4 PROTEIN (chains A,B,C,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Y3L", "evidence_id": "EV-PDB-2Y3L-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2Y3L", "doi": "10.1073/PNAS.1112600108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Y3L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "AMYLOID BETA A4 PROTEIN (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Y3J", "evidence_id": "EV-PDB-2Y3J-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "2Y3J", "doi": "10.1073/PNAS.1112600108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Y3J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of segment AIIGLM from the amyloid-beta peptide (Ab, residues 30-35)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "AMYLOID BETA A4 PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Y2A", "evidence_id": "EV-PDB-2Y2A-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.91}, "provenance": {"deposit_id": "2Y2A", "doi": "10.1073/PNAS.1112600108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Y2A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph I"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.25, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Beta-amyloid protein 40 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MVI", "evidence_id": "EV-PDB-4MVI-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4MVI", "doi": "10.1042/BCJ20160114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MVI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid peptide fragment VFFAED (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MVK", "evidence_id": "EV-PDB-4MVK-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4MVK", "doi": "10.1042/BCJ20160114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MVK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide fragment VFFAED"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Beta-amyloid protein 40 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MVL", "evidence_id": "EV-PDB-4MVL-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "4MVL", "doi": "10.1042/BCJ20160114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MVL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "GOL", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -159.65}, "construct": {"description": "Beta-amyloid protein 40 (chains B,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NGE", "evidence_id": "EV-PDB-4NGE-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.704}, "provenance": {"deposit_id": "4NGE", "doi": "10.1016/j.str.2014.05.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NGE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OJF", "evidence_id": "EV-PDB-4OJF-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.998}, "provenance": {"deposit_id": "4OJF", "doi": "10.1107/S2053230X14001642", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OJF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Humanised 3D6 Fab complexed to amyloid beta 1-8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4ONF", "evidence_id": "EV-PDB-4ONF-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4ONF", "doi": "10.1186/alzrt261", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4ONF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fab fragment of 3D6 in complex with amyloid beta 1-7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "IMD", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4ONG", "evidence_id": "EV-PDB-4ONG-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "4ONG", "doi": "10.1186/alzrt261", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4ONG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fab fragment of 3D6 in complex with amyloid beta 1-40"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PQD", "evidence_id": "EV-PDB-4PQD-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.332}, "provenance": {"deposit_id": "4PQD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PQD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The longer crystal structure of the grow factor like domain from Beta amypoid precusor protein (APP22-126)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PWQ", "evidence_id": "EV-PDB-4PWQ-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "4PWQ", "doi": "10.1016/j.jmb.2014.12.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PWQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN of THE AMYLOID PRECURSOR PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta fragment (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XXD", "evidence_id": "EV-PDB-4XXD-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.41}, "provenance": {"deposit_id": "4XXD", "doi": "10.1038/srep09649", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of mid-region amyloid beta capture by solanezumab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AMYLOID BETA A4 PROTEIN (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AEF", "evidence_id": "EV-PDB-5AEF-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.0}, "provenance": {"deposit_id": "5AEF", "doi": "10.1073/PNAS.1503455112", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AEF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Electron cryo-microscopy of an Abeta(1-42)amyloid fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "P6G", "PEG", "SO4", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BETA-AMYLOID PROTEIN 42 (chains P,Q,R,S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AM8", "evidence_id": "EV-PDB-5AM8-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "5AM8", "doi": "10.1111/FEBS.13647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AM8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 4-10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "P6G", "PEG", "PG4", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "AMYLOID BETA A4 PROTEIN (chains P,Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AMB", "evidence_id": "EV-PDB-5AMB-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "5AMB", "doi": "10.1111/FEBS.13647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AMB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 35-42"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C67", "evidence_id": "EV-PDB-5C67-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "5C67", "doi": "10.1042/BJ20151410", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C67"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Mesotrypsin in complex with amyloid precursor protein inhibitor variant APPI-M17G/I18F/F34V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5CSZ", "evidence_id": "EV-PDB-5CSZ-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "5CSZ", "doi": "10.3233/JAD-2011-110977", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5CSZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF GANTENERUMAB FAB FRAGMENT IN COMPLEX WITH ABETA 1-11"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -140.15}, "construct": {"description": "Amyloid beta A4 protein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HOW", "evidence_id": "EV-PDB-5HOW-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.295}, "provenance": {"deposit_id": "5HOW", "doi": "10.1021/jacs.6b01332", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystallographic structure of an Abeta 17-36 beta-hairpin. LV(PHI)FAEDCGSNKCAII(SAR)L(ORN)V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JEF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid beta A4 protein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HOX", "evidence_id": "EV-PDB-5HOX-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "5HOX", "doi": "10.1021/jacs.6b01332", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HOX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. Synchrotron data set. (LVFFAEDCGSNKCAII(SAR)LMV)."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JEF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -140.15}, "construct": {"description": "Amyloid beta A4 protein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HOY", "evidence_id": "EV-PDB-5HOY-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.295}, "provenance": {"deposit_id": "5HOY", "doi": "10.1021/jacs.6b01332", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HOY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. X-ray diffractometer data set. (LVFFAEDCGSNKCAII(SAR)LMV)."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Beta-amyloid protein 42 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KK3", "evidence_id": "EV-PDB-5KK3-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "5KK3", "doi": "10.1021/jacs.6b05129", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KK3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pyroglutamate-Abeta pE3-12-PEGb (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MY4", "evidence_id": "EV-PDB-5MY4-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.211}, "provenance": {"deposit_id": "5MY4", "doi": "10.1074/jbc.M117.777839", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MY4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pyroglutamate-Abeta-specific Fab c#17 in complex with human Abeta-pE3-12PEGb"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pyroglutamate-Abeta pE3-18 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MYX", "evidence_id": "EV-PDB-5MYX-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.492}, "provenance": {"deposit_id": "5MYX", "doi": "10.1074/jbc.M117.777839", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MYX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pyroglutamate-Abeta-specific Fab c#24 in complex with human Abeta-pE3-18"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NX1", "evidence_id": "EV-PDB-5NX1-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.853}, "provenance": {"deposit_id": "5NX1", "doi": "10.1074/jbc.RA117.000871", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NX1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NX1", "evidence_id": "EV-PDB-5NX1-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.853}, "provenance": {"deposit_id": "5NX1", "doi": "10.1074/jbc.RA117.000871", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NX1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NX1", "evidence_id": "EV-PDB-5NX1-4", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.853}, "provenance": {"deposit_id": "5NX1", "doi": "10.1074/jbc.RA117.000871", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NX1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NX3", "evidence_id": "EV-PDB-5NX3-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.296}, "provenance": {"deposit_id": "5NX3", "doi": "10.1074/jbc.RA117.000871", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NX3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NX3", "evidence_id": "EV-PDB-5NX3-3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.296}, "provenance": {"deposit_id": "5NX3", "doi": "10.1074/jbc.RA117.000871", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NX3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NX3", "evidence_id": "EV-PDB-5NX3-4", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.296}, "provenance": {"deposit_id": "5NX3", "doi": "10.1074/jbc.RA117.000871", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NX3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human Kallikrein 6 for Cancer Therapy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CD", "DMS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ONP", "evidence_id": "EV-PDB-5ONP-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.34}, "provenance": {"deposit_id": "5ONP", "doi": "10.1002/1873-3468.13285", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ONP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Cd-substituted Thermolysin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CD", "DMS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ONQ", "evidence_id": "EV-PDB-5ONQ-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.17}, "provenance": {"deposit_id": "5ONQ", "doi": "10.1002/1873-3468.13285", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ONQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Alzheimer's Amyloid-Beta Peptide Fragment 29-40 in Complex with Cd-substituted Thermolysin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DMS", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Amyloid-beta A4 protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ONR", "evidence_id": "EV-PDB-5ONR-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.39}, "provenance": {"deposit_id": "5ONR", "doi": "10.1002/1873-3468.13285", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ONR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Thermolysin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid beta A4 protein (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OQV", "evidence_id": "EV-PDB-5OQV-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "5OQV", "doi": "10.1126/science.aao2825", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Near-atomic resolution fibril structure of complete amyloid-beta(1-42) by cryo-EM"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["UNX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,B,C,D,E,F,G,H,I,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q4B", "evidence_id": "EV-PDB-7Q4B-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7Q4B", "doi": "10.1126/science.abm7285", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q4B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type I beta-amyloid 42 Filaments from Human Brain"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-hemolysin hybridized Abeta (chains A,B,C,D,E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O1Q", "evidence_id": "EV-PDB-7O1Q-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7O1Q", "doi": "10.1002/anie.202104497", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O1Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Amyloid beta oligomer displayed on the alpha hemolysin scaffold"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -150.0}, "construct": {"description": "Amyloid-beta 17-36 peptide (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JXN", "evidence_id": "EV-PDB-7JXN-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "7JXN", "doi": "10.1021/jacs.0c09281", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JXN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Beta hairpin derived from Abeta17-36 with an F20Cha mutation"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "Isoform L-APP677 of Amyloid-beta precursor protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B3K", "evidence_id": "EV-PDB-7B3K-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7B3K", "doi": "10.1021/acs.jmedchem.1c00632", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B3K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Dynamic complex between all-D-enantiomeric peptide D3 with L723P mutant of amyloid precursor protein (APP) 672-726 fragment (amyloid beta 1-55)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Amyloid-beta precursor protein G38P mutant (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YHO", "evidence_id": "EV-PDB-6YHO-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6YHO", "doi": "10.1021/acschemneuro.0c00640", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YHO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution NMR Structure of APP G38P mutant TM"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["YWK"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "amyloid beta segment 35-MVGGVV-40, racemic mixture (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T82", "evidence_id": "EV-PDB-8T82-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "8T82", "doi": "10.1021/jacs.3c11712", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T82"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes pentafluoropropionic acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TFA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Racemic mixture of amyloid beta segment 16-KLVFFA-21 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T89", "evidence_id": "EV-PDB-8T89-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "8T89", "doi": "10.1021/jacs.3c11712", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T89"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Racemic mixture of amyloid beta segment 16-KLVFFA-21 forms heterochiral rippled beta-sheet"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CLR", "NAG", "PC1", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X52", "evidence_id": "EV-PDB-8X52-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8X52", "doi": "10.1126/science.adn5820", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X52"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human gamma-secretase in complex with Abeta49"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CLR", "NAG", "PC1", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X54", "evidence_id": "EV-PDB-8X54-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8X54", "doi": "10.1126/science.adn5820", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X54"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human gamma-secretase in complex with APP-C99"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains e)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z9V", "evidence_id": "EV-PDB-8Z9V-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.84}, "provenance": {"deposit_id": "8Z9V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z9V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Amyloid beta and TTR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A8F", "evidence_id": "EV-PDB-9A8F-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A8F", "doi": "10.1126/sciadv.adr7008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A8F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Type II Amyloid beta Fibril MEMMI ensemble"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Beta-amyloid protein 42 (chains A,B,C,D,E,F,G,H,I,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CK6", "evidence_id": "EV-PDB-9CK6-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9CK6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CK6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of sarkosyl insoluble amyloid-beta 42 filaments extracted from human brain tissue"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Beta-amyloid protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CKI", "evidence_id": "EV-PDB-9CKI-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9CKI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CKI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the poly(4-styrenesulfonic acid-co-maleic acid) [PSCMA]-extractable amyloid-beta 42 oligomer from human brain tissue (Conformation 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CZN", "evidence_id": "EV-PDB-9CZN-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9CZN", "doi": "10.1007/s00401-024-02786-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CZN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type Ic amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CZP", "evidence_id": "EV-PDB-9CZP-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9CZP", "doi": "10.1007/s00401-024-02786-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CZP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type Id amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FH3", "evidence_id": "EV-PDB-9FH3-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "9FH3", "doi": "10.1186/s40478-025-02120-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FH3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FH4", "evidence_id": "EV-PDB-9FH4-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9FH4", "doi": "10.1186/s40478-025-02120-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FH4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FH5", "evidence_id": "EV-PDB-9FH5-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9FH5", "doi": "10.1186/s40478-025-02120-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FH5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 40 (chains 2,3,4,5,6,A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,a,b,c,d,e,f,g,h,i)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IIO", "evidence_id": "EV-PDB-9IIO-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9IIO", "doi": "10.3390/ijms26031179", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IIO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "J-shaped conformer of amyloid beta (1-40)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,AA,B,BB,C,CC,D,DD,E,EE,F,FF)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JAZ", "evidence_id": "EV-PDB-9JAZ-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9JAZ", "doi": "10.1016/j.jmb.2025.169092", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JAZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the class I amyloid-beta 42 fibril containing a D-Asp at position 23"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains FF,FG,FH,FI,FJ,FK,FL,FM,FN,FO,FP,FQ)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JB1", "evidence_id": "EV-PDB-9JB1-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "9JB1", "doi": "10.1016/j.jmb.2025.169092", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JB1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the type I amyloid-beta 42 fibril containing a D-Asp at positions 7 and 23"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 40 (chains B,F,K,L,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K0D", "evidence_id": "EV-PDB-9K0D-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9K0D", "doi": "10.1038/s41467-025-60978-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K0D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Amyloid-beta42-4b polymorph 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 40 (chains A,D,E,F,L,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K0E", "evidence_id": "EV-PDB-9K0E-2", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9K0E", "doi": "10.1038/s41467-025-60978-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K0E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Amyloid-beta42-4b polymorph 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,B,BA,BB,BC,BD,BE,C,CA,CB,CC,CD,CE,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JB2", "evidence_id": "EV-PDB-9JB2-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9JB2", "doi": "10.1016/j.jmb.2025.169092", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JB2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the type II amyloid-beta 42 fibril containing a D-Asp at positions 7 and 23"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,AA,B,BB,C,CC,D,DD,E,EE,F,FF)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JB0", "evidence_id": "EV-PDB-9JB0-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9JB0", "doi": "10.1016/j.jmb.2025.169092", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the class II amyloid-beta 42 fibril containing a D-Asp at position 23"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta precursor protein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FH2", "evidence_id": "EV-PDB-9FH2-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9FH2", "doi": "10.1186/s40478-025-02120-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FH2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Beta-amyloid protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CO4", "evidence_id": "EV-PDB-9CO4-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9CO4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CO4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the receptor-bound amyloid-beta 42 oligomer from human brain tissue (Conformation 1)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SEJ", "evidence_id": "EV-PDB-8SEJ-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.17}, "provenance": {"deposit_id": "8SEJ", "doi": "10.1038/s41594-024-01252-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SEJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type I beta-amyloid 42 Filaments from Down syndrome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OLQ", "evidence_id": "EV-PDB-8OLQ-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "8OLQ", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OLQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DI3 Abeta fibril from tg-SwDI mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OLO", "evidence_id": "EV-PDB-8OLO-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8OLO", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OLO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Murine type III Abeta fibril from ARTE10 mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OLN", "evidence_id": "EV-PDB-8OLN-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8OLN", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OLN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DI1 Abeta fibril from tg-SwDI mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OLG", "evidence_id": "EV-PDB-8OLG-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "8OLG", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OLG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DI2 Abeta fibril from tg-SwDI mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OL7", "evidence_id": "EV-PDB-8OL7-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8OL7", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OL7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "MurineArc type I Abeta fibril from tg-APPArcSwe mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OL6", "evidence_id": "EV-PDB-8OL6-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8OL6", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OL6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Murine type II Abeta fibril from tgAPPSwe mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OL5", "evidence_id": "EV-PDB-8OL5-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8OL5", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OL5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Murine type II Abeta fibril from ARTE10 mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Amyloid-beta protein 42 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OL2", "evidence_id": "EV-PDB-8OL2-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8OL2", "doi": "10.1038/s41593-023-01484-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OL2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Murine type II Abeta fibril from APP23 mouse"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "P3(40) (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8KF6", "evidence_id": "EV-PDB-8KF6-1", "mappings": [], "molecule_id": "P05067", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8KF6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8KF6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 2.0, "salt_mM": null, "temperature_c": 5.0}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51321", "evidence_id": "EV-BMRB-51321", "mappings": [], "molecule_id": "P05067", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51321", "doi": "10.13018/BMR51321", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51321"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Sequence-specific Backbone Resonance Assignments of Human Amyloid-beta(1-42) in 28% Acetonitrile at pH 2.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 5.0}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51322", "evidence_id": "EV-BMRB-51322", "mappings": [], "molecule_id": "P05067", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51322", "doi": "10.13018/BMR51322", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51322"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Sequence-specific Backbone Resonance Assignments of Human Amyloid-beta(1-42) at pH 7.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 2.0, "salt_mM": null, "temperature_c": 5.0}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51323", "evidence_id": "EV-BMRB-51323", "mappings": [], "molecule_id": "P05067", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51323", "doi": "10.13018/BMR51323", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51323"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Sequence-specific Backbone Resonance Assignments of Human Amyloid-beta(1-42) at pH 2.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51584", "evidence_id": "EV-BMRB-51584", "mappings": [], "molecule_id": "P05067", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51584", "doi": "10.13018/BMR51584", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51584"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 13C and 15N Chemical Shift Assignments for fibrillar Amyloid Beta (1-42) at pH 7.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 2.0, "salt_mM": null, "temperature_c": -10.15}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51993", "evidence_id": "EV-BMRB-51993", "mappings": [], "molecule_id": "P05067", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51993", "doi": "10.13018/BMR51993", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51993"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 13C and 15N Chemical Shift Assignments for Fibrils of Pyroglutamate Amyloid beta (3-42) at pH 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5400", "evidence_id": "EV-BMRB-5400", "mappings": [], "molecule_id": "P05067", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5400", "doi": "10.13018/BMR5400", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5400"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide abeta 1-42 by mirror image phage display"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.4, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=6236", "evidence_id": "EV-BMRB-6236", "mappings": [], "molecule_id": "P05067", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr6236", "doi": "10.13018/BMR6236", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=6236"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments for CAPPD*, an Independently Folded Extracellular Domain of Human Amyloid-beta Precursor Protein"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris,  100 mM NaCl , 20 mM EDTA", "environment": "in_vitro", "ions": [], "ligands": ["partner: Presequence protease, mitochondrial"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.5 nm.", "ph": 7.7, "salt_mM": null, "temperature_c": 22.0}, "construct": {"description": "Amyloid-beta precursor protein with Presequence protease, mitochondrial", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDKN3/", "evidence_id": "EV-SASBDB-SASDKN3", "mappings": [], "molecule_id": "P05067", "observable": {"type": "radius_of_gyration", "uncertainty": 0.24, "unit": "nm", "value": 3.037}, "provenance": {"deposit_id": "SASDKN3", "doi": "10.1038/s41467-022-29322-4", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDKN3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition"}
{"conditions": {"applied_force_pn": null, "buffer": "1 mM Hepes, 0.12 % NH4OH", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 42 nm.", "ph": 10.7, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Amyloid-beta precursor protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPP7/", "evidence_id": "EV-SASBDB-SASDPP7", "mappings": [], "molecule_id": "P05067", "observable": {"type": "radius_of_gyration", "uncertainty": 0.151, "unit": "nm", "value": 5.81}, "provenance": {"deposit_id": "SASDPP7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPP7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation"}
{"conditions": {"applied_force_pn": null, "buffer": "1 mM Hepes, 0.12 % NH4OH", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 60 nm.", "ph": 10.7, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Amyloid-beta precursor protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPQ7/", "evidence_id": "EV-SASBDB-SASDPQ7", "mappings": [], "molecule_id": "P05067", "observable": {"type": "radius_of_gyration", "uncertainty": 1.601, "unit": "nm", "value": 6.863}, "provenance": {"deposit_id": "SASDPQ7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPQ7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation"}
{"conditions": {"applied_force_pn": null, "buffer": "1 mM Hepes, 0.1 % NH4OH (pH∼10.7)", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.51 nm.", "ph": 10.7, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Amyloid-beta precursor protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPR7/", "evidence_id": "EV-SASBDB-SASDPR7", "mappings": [], "molecule_id": "P05067", "observable": {"type": "radius_of_gyration", "uncertainty": 0.044, "unit": "nm", "value": 2.5}, "provenance": {"deposit_id": "SASDPR7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPR7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation"}
{"conditions": {"applied_force_pn": null, "buffer": "1 mM Hepes, 0.1 % NH4OH (pH∼10.7)", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.11 nm.", "ph": 10.7, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Amyloid-beta precursor protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPS7/", "evidence_id": "EV-SASBDB-SASDPS7", "mappings": [], "molecule_id": "P05067", "observable": {"type": "radius_of_gyration", "uncertainty": 0.131, "unit": "nm", "value": 3.73}, "provenance": {"deposit_id": "SASDPS7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPS7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation"}
{"conditions": {"applied_force_pn": null, "buffer": "1 mM Hepes, 0.1 % NH4OH (pH∼10.7)", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 11 nm.", "ph": 10.7, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Amyloid-beta precursor protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPT7/", "evidence_id": "EV-SASBDB-SASDPT7", "mappings": [], "molecule_id": "P05067", "observable": {"type": "radius_of_gyration", "uncertainty": 0.362, "unit": "nm", "value": 3.73}, "provenance": {"deposit_id": "SASDPT7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPT7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation"}
{"conditions": {"applied_force_pn": null, "buffer": "1 mM Hepes, 0.12 % NH4OH", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 15 nm.", "ph": 10.7, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Amyloid-beta precursor protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPU7/", "evidence_id": "EV-SASBDB-SASDPU7", "mappings": [], "molecule_id": "P05067", "observable": {"type": "radius_of_gyration", "uncertainty": 0.114, "unit": "nm", "value": 3.504}, "provenance": {"deposit_id": "SASDPU7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPU7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 672-711; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/9737846", "evidence_id": "EV-DISPROT-DP01280r001", "mappings": [], "molecule_id": "P05067", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 40}, "provenance": {"deposit_id": "DP01280r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01280"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP01280: disorder, residues 672-711"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 672-711; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/9737846", "evidence_id": "EV-DISPROT-DP01280r003", "mappings": [], "molecule_id": "P05067", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 40}, "provenance": {"deposit_id": "DP01280r003", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01280"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP01280: disorder to order, residues 672-711"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 672-686; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/9737846", "evidence_id": "EV-DISPROT-DP01280r004", "mappings": [], "molecule_id": "P05067", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 15}, "provenance": {"deposit_id": "DP01280r004", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01280"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP01280: disorder, residues 672-686"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 672-711; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26138908", "evidence_id": "EV-DISPROT-DP01280r005", "mappings": [], "molecule_id": "P05067", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 40}, "provenance": {"deposit_id": "DP01280r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01280"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP01280: disorder, residues 672-711"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Lupus La protein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9NF8", "evidence_id": "EV-PDB-9NF8-2", "mappings": [], "molecule_id": "P05455", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9NF8", "doi": "10.1016/j.cell.2025.12.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9NF8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Ro60/La/truncated misfolded human pre-5S rRNA complex with Fab, composite map"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Lupus La protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1S7A", "evidence_id": "EV-PDB-1S7A-1", "mappings": [], "molecule_id": "P05455", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1S7A", "doi": "10.1038/nsmb747", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1S7A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of the La motif of human La protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=15726", "evidence_id": "EV-BMRB-15726", "mappings": [], "molecule_id": "P05455", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr15726", "doi": "10.13018/BMR15726", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=15726"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments for La NTD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=15727", "evidence_id": "EV-BMRB-15727", "mappings": [], "molecule_id": "P05455", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr15727", "doi": "10.13018/BMR15727", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=15727"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Full 1H, 13C, and 15N Chemical Shift Assignments for La NTD complexed with 5'UUUU RNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.25, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17878", "evidence_id": "EV-BMRB-17878", "mappings": [], "molecule_id": "P05455", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17878", "doi": "10.13018/BMR17878", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17878"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments for La(4-325)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5235", "evidence_id": "EV-BMRB-5235", "mappings": [], "molecule_id": "P05455", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5235", "doi": "10.13018/BMR5235", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5235"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Resonance assignment and secondary structure determination of a C-terminal fragment of the Lupus Autoantigen (La) protein containing a putative RNA recognition motif (RRM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5719", "evidence_id": "EV-BMRB-5719", "mappings": [], "molecule_id": "P05455", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5719", "doi": "10.13018/BMR5719", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5719"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Resonance assignment and secondary structure of an N-terminal fragment of the human La protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=6044", "evidence_id": "EV-BMRB-6044", "mappings": [], "molecule_id": "P05455", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr6044", "doi": "10.13018/BMR6044", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=6044"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Resonance assignment and secondary structure of the La motif"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 326-408; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/12842046", "evidence_id": "EV-DISPROT-DP00229r001", "mappings": [], "molecule_id": "P05455", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 83}, "provenance": {"deposit_id": "DP00229r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP00229"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP00229: disorder, residues 326-408"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-408", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P05455", "evidence_id": "EV-AFDB-AF-P05455-F1", "mappings": [], "molecule_id": "P05455", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 74.5}, "provenance": {"deposit_id": "AF-P05455-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P05455"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P05455-F1"}
{"components": [], "domains": [{"end": 76, "name": "PSI", "start": 26}, {"end": 378, "name": "VWFA", "start": 140}, {"end": 501, "name": "I-EGF 1", "start": 466}, {"end": 554, "name": "I-EGF 2", "start": 502}, {"end": 591, "name": "I-EGF 3", "start": 555}, {"end": 631, "name": "I-EGF 4", "start": 592}], "gene": "ITGB1", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P05556"}, "ligands": ["Ca(2+)", "Mg(2+)"], "modifications": [{"kind": "ptm", "name": "Phosphothreonine", "position": 777, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine", "position": 783, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 785, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine", "position": 789, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine; alternate", "position": 794, "source": "UniProtKB"}], "molecule_id": "P05556", "molecule_type": "protein", "name": "Integrin beta-1", "organism": {"name": "Homo sapiens", "taxon_id": 9606}, "provenance": {"deposit_id": "P05556", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05556/entry"}, "record_type": "molecule", "sequence": "MNLQPIFWIGLISSVCCVFAQTDENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPKKDSDSFKIRPLGFTEEVEVILQYICECECQSEGIPESPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGICECGVCKCTDPKFQGQTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDTCTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVENPECPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK", "sequence_length": 798}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WK2", "evidence_id": "EV-PDB-4WK2-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "4WK2", "doi": "10.1073/pnas.1420645111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WK2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Metal Ion and Ligand Binding of Integrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9P6S", "evidence_id": "EV-PDB-9P6S-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "9P6S", "doi": "10.1093/pnasnexus/pgag044", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9P6S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human integrin alpha5beta1 in complex with fibronectin (FN 7-10)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9NAB", "evidence_id": "EV-PDB-9NAB-1", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.54}, "provenance": {"deposit_id": "9NAB", "doi": "10.1002/advs.202513672", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9NAB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the alpha5beta1 integrin headpiece with OS2966 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EF2", "evidence_id": "EV-PDB-9EF2-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "9EF2", "doi": "10.1002/adma.202500872", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EF2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin candidate 2, open conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DIA", "evidence_id": "EV-PDB-9DIA-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "9DIA", "doi": "10.1002/adma.202500872", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DIA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin candidate 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CKV", "evidence_id": "EV-PDB-9CKV-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "9CKV", "doi": "10.1002/adma.202500872", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CKV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B9K", "evidence_id": "EV-PDB-9B9K-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9B9K", "doi": "10.1101/2025.01.08.631572", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B9K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Integrin alpha-5 beta-1 in complex with MINT1526A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B9J", "evidence_id": "EV-PDB-9B9J-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9B9J", "doi": "10.1101/2025.01.08.631572", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Integrin alpha-5 beta-1 in complex with BIIG2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AFA", "CA", "NAG", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8W30", "evidence_id": "EV-PDB-8W30-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "8W30", "doi": "10.1021/acs.jmedchem.4c00743", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8W30"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of alpha-V beta-1 integrin headpiece in complex with TR01225179"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Integrin beta-1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RPQ", "evidence_id": "EV-PDB-8RPQ-1", "mappings": [], "molecule_id": "P05556", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8RPQ", "doi": "10.1021/acschemneuro.4c00068", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution NMR structure of Integrin beta-1 TMD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NXD", "evidence_id": "EV-PDB-7NXD-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "7NXD", "doi": "10.1126/sciadv.abe9716", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NWL", "evidence_id": "EV-PDB-7NWL-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7NWL", "doi": "10.1126/sciadv.abe9716", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NWL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CEC", "evidence_id": "EV-PDB-7CEC-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7CEC", "doi": "10.1038/s41467-021-24184-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of alpha6beta1 integrin in complex with laminin-511"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CEB", "evidence_id": "EV-PDB-7CEB-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "7CEB", "doi": "10.1038/s41467-021-24184-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of alpha6beta1 integrin headpiece"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WK4", "evidence_id": "EV-PDB-4WK4-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "4WK4", "doi": "10.1073/pnas.1420645111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WK4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Metal Ion and Ligand Binding of Integrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WK0", "evidence_id": "EV-PDB-4WK0-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.78}, "provenance": {"deposit_id": "4WK0", "doi": "10.1073/pnas.1420645111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WK0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Metal Ion and Ligand Binding of Integrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WJK", "evidence_id": "EV-PDB-4WJK-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "4WJK", "doi": "10.1073/pnas.1420645111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WJK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Metal Ion and Ligand Binding of Integrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1 (chains 6,7,8,9,B,D,F,H,J,L,N,P,R,T,V,X,Z,b,d,f,h,j,l,n,p,r,t,v,x,z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DX9", "evidence_id": "EV-PDB-4DX9-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "4DX9", "doi": "10.1016/j.molcel.2012.12.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ICAP1 in complex with integrin beta 1 cytoplasmic tail"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "Integrin beta-1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3VI4", "evidence_id": "EV-PDB-3VI4-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "3VI4", "doi": "10.1083/jcb.201111077", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3VI4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of alpha5beta1 integrin headpiece in complex with RGD peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MG", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "Integrin beta-1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3VI3", "evidence_id": "EV-PDB-3VI3-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "3VI3", "doi": "10.1083/jcb.201111077", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3VI3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of alpha5beta1 integrin headpiece (ligand-free form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3T9K", "evidence_id": "EV-PDB-3T9K-1", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3T9K", "doi": "10.1074/jbc.M112.378810", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3T9K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of ACAP1 C-portion mutant S554D fused with integrin beta1 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-1D (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3G9W", "evidence_id": "EV-PDB-3G9W-2", "mappings": [], "molecule_id": "P05556", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.165}, "provenance": {"deposit_id": "3G9W", "doi": "10.1038/emboj.2009.287", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3G9W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.1, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=16159", "evidence_id": "EV-BMRB-16159", "mappings": [], "molecule_id": "P05556", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr16159", "doi": "10.13018/BMR16159", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=16159"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Beta1A Integrin Cytoplasmic Tail 1H and 15N Chemical Shift Assignments"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34892", "evidence_id": "EV-BMRB-34892", "mappings": [], "molecule_id": "P05556", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr34892", "doi": "10.13018/BMR34892", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34892"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution NMR structure of Integrin beta-1 TMD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 752-798; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/12500944", "evidence_id": "EV-DISPROT-DP01748r002", "mappings": [], "molecule_id": "P05556", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 47}, "provenance": {"deposit_id": "DP01748r002", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01748"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP01748: disorder, residues 752-798"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 784-798; evidence: x-ray crystallography evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/23317506", "evidence_id": "EV-DISPROT-DP01748r005", "mappings": [], "molecule_id": "P05556", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 15}, "provenance": {"deposit_id": "DP01748r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01748"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP01748: disorder to order, residues 784-798"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-798", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P05556", "evidence_id": "EV-AFDB-AF-P05556-F1", "mappings": [], "molecule_id": "P05556", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 85.88}, "provenance": {"deposit_id": "AF-P05556-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P05556"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P05556-F1"}
{"components": [], "domains": [], "gene": "spg", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P06654"}, "ligands": [], "modifications": [{"kind": "ptm", "name": "Pentaglycyl murein peptidoglycan amidated threonine", "position": 417, "source": "UniProtKB"}], "molecule_id": "P06654", "molecule_type": "protein", "name": "Immunoglobulin G-binding protein G", "organism": {"name": "Streptococcus sp. group G", "taxon_id": 1320}, "provenance": {"deposit_id": "P06654", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P06654/entry"}, "record_type": "molecule", "sequence": "MEKEKKVKYFLRKSAFGLASVSAAFLVGSTVFAVDSPIEDTPIIRNGGELTNLLGNSETTLALRNEESATADLTAAAVADTVAAAAAENAGAAAWEAAAAADALAKAKADALKEFNKYGVSDYYKNLINNAKTVEGIKDLQAQVVESAKKARISEATDGLSDFLKSQTPAEDTVKSIELAEAKVLANRELDKYGVSDYHKNLINNAKTVEGVKELIDEILAALPKTDTYKLILNGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTEKPEVIDASELTPAVTTYKLVINGKTLKGETTTKAVDAETAEKAFKQYANDNGVDGVWTYDDATKTFTVTEMVTEVPGDAPTEPEKPEASIPLVPLTPATPIAKDDAKKDDTKKEDAKKPEAKKDDAKKAETLPTTGEGSNPFFTAAALAVMAGAGALAVASKRKED", "sequence_length": 448}
{"assumptions": [], "basis": "observed", "description": "Native fold of the B1 domain, as in 1PGA. Force and ensemble data are not yet ingested.", "family_label": null, "molecule_id": "P06654", "name": "native fold", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P06654.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P06654.yaml"}, "record_type": "state", "representative_model": "GB1-native-cif", "secondary_structure": null, "state_id": "GB1-native", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PROTEIN G (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1GB1", "evidence_id": "EV-PDB-1GB1-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1GB1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1GB1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "A NOVEL, HIGHLY STABLE FOLD OF THE IMMUNOGLOBULIN BINDING DOMAIN OF STREPTOCOCCAL PROTEIN G"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PROTEIN G (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IGD", "evidence_id": "EV-PDB-1IGD-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "1IGD", "doi": "10.1006/jmbi.1994.1691", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IGD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE THIRD IGG-BINDING DOMAIN FROM STREPTOCOCCAL PROTEIN G: AN ANALYSIS BY X-RAY CRYSTALLOGRAPHY OF THE STRUCTURE ALONE AND IN A COMPLEX WITH FAB"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.45, "salt_mM": null, "temperature_c": 39.85}, "construct": {"description": "Immunoglobulin G binding protein G (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MPE", "evidence_id": "EV-PDB-1MPE-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as the B1 domain; the UniProt entry covers all protein G domains, so other domains are excluded by title.", "rule": "gb1-structures-native", "state_id": "GB1-native", "who": "rule:gb1-structures-native"}], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1MPE", "doi": "10.1038/nsb854", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MPE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Ensemble of 20 structures of the tetrameric mutant of the B1 domain of streptococcal protein G"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PROTEIN G (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PGA", "evidence_id": "EV-PDB-1PGA-1", "mappings": [{"confidence": "high", "justification": "Native B1 domain at 2.07 Å; representative for the native fold.", "rule": "curator_assignment", "state_id": "GB1-native", "who": "curator:draft (unreviewed)"}], "molecule_id": "P06654", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.07}, "provenance": {"deposit_id": "1PGA", "doi": "10.1021/bi00181a032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PGA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "TWO CRYSTAL STRUCTURES OF THE B1 IMMUNOGLOBULIN-BINDING DOMAIN OF STREPTOCOCCAL PROTEIN G AND COMPARISON WITH NMR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PROTEIN G (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PGX", "evidence_id": "EV-PDB-1PGX-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as the B1 domain; the UniProt entry covers all protein G domains, so other domains are excluded by title.", "rule": "gb1-structures-native", "state_id": "GB1-native", "who": "rule:gb1-structures-native"}], "molecule_id": "P06654", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.66}, "provenance": {"deposit_id": "1PGX", "doi": "10.1021/bi00158a006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PGX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE 1.66 ANGSTROMS X-RAY STRUCTURE OF THE B2 IMMUNOGLOBULIN-BINDING DOMAIN OF STREPTOCOCCAL PROTEIN G AND COMPARISON TO THE NMR STRUCTURE OF THE B1 DOMAIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "NACHT-, LRR- and PYD-containing protein 2 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PN5", "evidence_id": "EV-PDB-1PN5-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1PN5", "doi": "10.1016/j.str.2003.08.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of the NALP1 Pyrin domain (PYD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "PROTEIN G (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2IGD", "evidence_id": "EV-PDB-2IGD-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "2IGD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2IGD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ANISOTROPIC STRUCTURE OF PROTEIN G IGG-BINDING DOMAIN III AT 1.1 ANGSTROM RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PROTEIN G (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2IGH", "evidence_id": "EV-PDB-2IGH-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2IGH", "doi": "10.1016/0022-2836(92)90328-H", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2IGH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "DETERMINATION OF THE SOLUTION STRUCTURES OF DOMAINS II AND III OF PROTEIN G FROM STREPTOCOCCUS BY 1H NMR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Immunoglobulin G-binding protein G (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LGI", "evidence_id": "EV-PDB-2LGI-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LGI", "doi": "10.1073/pnas.1103728108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LGI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Atomic Resolution Protein Structures using NMR Chemical Shift Tensors"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Immunoglobulin G-binding protein G (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2PLP", "evidence_id": "EV-PDB-2PLP-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as the B1 domain; the UniProt entry covers all protein G domains, so other domains are excluded by title.", "rule": "gb1-structures-native", "state_id": "GB1-native", "who": "rule:gb1-structures-native"}], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2PLP", "doi": "10.1002/anie.200603627", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2PLP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Ultra high resolution backbone conformation of protein GB1 from residual dipolar couplings alone"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "PROTEIN (B1 DOMAIN OF STREPTOCOCCAL PROTEIN G) (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3GB1", "evidence_id": "EV-PDB-3GB1-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as the B1 domain; the UniProt entry covers all protein G domains, so other domains are excluded by title.", "rule": "gb1-structures-native", "state_id": "GB1-native", "who": "rule:gb1-structures-native"}], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "3GB1", "doi": "10.1021/ja9843730", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3GB1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "STRUCTURES OF B1 DOMAIN OF STREPTOCOCCAL PROTEIN G"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "Immunoglobulin G-binding protein G (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QTS", "evidence_id": "EV-PDB-7QTS-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as the B1 domain; the UniProt entry covers all protein G domains, so other domains are excluded by title.", "rule": "gb1-structures-native", "state_id": "GB1-native", "who": "rule:gb1-structures-native"}], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7QTS", "doi": "10.1038/s42003-022-04251-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QTS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "GB1 in mammalian cells, 10 uM"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Immunoglobulin G-binding protein G (chains A)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A1D", "evidence_id": "EV-PDB-9A1D-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A1D", "doi": "10.1038/s41467-023-36065-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A1D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "CS-Rosetta structure of engineered IgG-binding domain of protein G (GB) - model B4"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Immunoglobulin G-binding protein G,Cullin-5 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6V9I", "evidence_id": "EV-PDB-6V9I-1", "mappings": [], "molecule_id": "P06654", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.2}, "provenance": {"deposit_id": "6V9I", "doi": "10.1038/s41467-020-16499-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6V9I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of Cullin5 bound to RING-box protein 2 (Cul5-Rbx2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Immunoglobulin G-binding protein G (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6L91", "evidence_id": "EV-PDB-6L91-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as the B1 domain; the UniProt entry covers all protein G domains, so other domains are excluded by title.", "rule": "gb1-structures-native", "state_id": "GB1-native", "who": "rule:gb1-structures-native"}], "molecule_id": "P06654", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.842}, "provenance": {"deposit_id": "6L91", "doi": "10.1039/d0sc03060k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6L91"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of synthetic GB1 domain with the mutation K10(DVA)."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Immunoglobulin G-binding protein G (chains A,B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RMM", "evidence_id": "EV-PDB-2RMM-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as the B1 domain; the UniProt entry covers all protein G domains, so other domains are excluded by title.", "rule": "gb1-structures-native", "state_id": "GB1-native", "who": "rule:gb1-structures-native"}], "molecule_id": "P06654", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2RMM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RMM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of GB1 A34F mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["12P", "1PE", "A1JHU", "ACM", "CLR", "EDO", "GOL", "OLC", "PLM", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Beta-2 adrenergic receptor,Endolysin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RKG", "evidence_id": "EV-PDB-9RKG-1", "mappings": [], "molecule_id": "P07550", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "9RKG", "doi": "10.1002/anie.202517995", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RKG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mixed model refinement of beta-2 Adrenergic receptor with photoazolol in dark state and Light state, 10 seconds after light activation, recorded at SwissFEL"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EV3", "CLR", "G4C", "PLM", "SK0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Beta-2 adrenergic receptor,D(1A) dopamine receptor,Engineered oplophorus-luciferin 2-monooxygenase catalytic subunit (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WEU", "evidence_id": "EV-PDB-9WEU-5", "mappings": [], "molecule_id": "P07550", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "9WEU", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WEU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "D1R-Gs in complexed with SKF81297/LY3154207/BMSA1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=36284", "evidence_id": "EV-BMRB-36284", "mappings": [], "molecule_id": "P07550", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr36284", "doi": "10.13018/BMR36284", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=36284"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Structure of the beta2 adrenergic receptor in the full agonist bound state"}
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{"components": [], "domains": [{"end": 1026, "name": "SH3", "start": 967}, {"end": 2363, "name": "EF-hand 1", "start": 2328}, {"end": 2406, "name": "EF-hand 2", "start": 2371}, {"end": 2444, "name": "EF-hand 3", "start": 2409}], "gene": "SPTAN1", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P07751"}, "ligands": ["Ca(2+)"], "modifications": [{"kind": "ptm", "name": "Phosphotyrosine", "position": 1176, "source": "UniProtKB"}], "molecule_id": "P07751", "molecule_type": "protein", "name": "Spectrin alpha chain, non-erythrocytic 1", "organism": {"name": "Gallus gallus", "taxon_id": 9031}, "provenance": {"deposit_id": "P07751", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07751/entry"}, "record_type": "molecule", "sequence": "MDPSGVKVLETAEDIQERRQQVLDRYHRFKELSSLRRQKLEDSYRFQFFQRDADELGKWIQEKLQIASDENYKDPSNLQGKLQKHQAFEAEVQANSGAIVKLDETGNQMINEGHFASETIRTRLQELHRLWELLLEKMREKGVKLLQAQKLVQFLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVNEVNQFAGKLIQEQHPEEELIKSKQDEVNASWQRLKGLAQQRQGKLFGAAEVQRFNRDVDETISWIKEKGQLMASDDFGRDLASVQALLRKHEGLERDLAAFHHKVKALCAEADRLQQSHPINASQIQVKREELIANWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFRSADESGQALLAAGHYASDEVKEKLTILSDERSALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMDDVATRRDALLSRRNALHERAMKRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYASDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQDPIDGITIQARQFQDAGHFDADNIKKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDIEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKIKLNELNQKWDSLKAKASQRRQDLEDSLQAQQYFADANEAQSWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQIDNQTLITKEVGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVANDLESEGLMAEEVQAVEHQEVYGMMPRDETDSKTVSPWKSARMMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSADEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRNDEGFERDLAALGDKVNSLGETAQRLIQSHPELAEDLQEKCTELNQAWSSLGKRADQRKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLARGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAVLQSFADQLIAADHYAKGVIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRIRGVIEMGNPLIERGACAGSEDAVKARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRETINGRFQRIKSMAAARRAKLNESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQFVDHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCANGEDLIKKNNHHVENITAKMKGLKGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEVRHASLMKRWNQLLANSAARKKKLLEAQEHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFESILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSERKPYVTKEELYQNLTREQADYCISHMKPYMDGKGRELPSAYDYIEFTRSLFVN", "sequence_length": 2477}
{"assumptions": [], "basis": "observed", "description": "Native fold of the alpha-spectrin SH3 domain, as in 1SHG.", "family_label": null, "molecule_id": "P07751", "name": "native fold", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P07751.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P07751.yaml"}, "record_type": "state", "representative_model": "SH3-native-cif", "secondary_structure": null, "state_id": "SH3-native", "status": "draft"}
{"assumptions": ["Treated as a single ensemble; residual structure and intermediates are not resolved.", "Defined by indirect measurements (denaturation, NMR of denatured samples, force spectroscopy); no model is exported."], "basis": "inferred", "description": "Unfolded ensemble reached by denaturant, temperature or force. No observed structure.", "family_label": null, "molecule_id": "P07751", "name": "unfolded", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P07751.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P07751.yaml"}, "record_type": "state", "representative_model": null, "secondary_structure": null, "state_id": "SH3-unfolded", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M0S", "evidence_id": "EV-PDB-3M0S-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3M0S", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M0S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, non-erythrocytic 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IHN", "evidence_id": "EV-PDB-5IHN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "5IHN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IHN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the alpha spectrin SH3 domain mutant N47G"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "PRO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, non-erythrocytic 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IHK", "evidence_id": "EV-PDB-5IHK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "5IHK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IHK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the alpha spectrin SH3 domain mutant N47A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, non-erythrocytic 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IHI", "evidence_id": "EV-PDB-5IHI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "5IHI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IHI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4F17", "evidence_id": "EV-PDB-4F17-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "4F17", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4F17"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the alpha spectrin SH3 domain at pH 9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4F16", "evidence_id": "EV-PDB-4F16-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.93}, "provenance": {"deposit_id": "4F16", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4F16"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the alpha spectrin SH3 domain at pH 5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3NGP", "evidence_id": "EV-PDB-3NGP-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.084}, "provenance": {"deposit_id": "3NGP", "doi": "10.1107/S1744309110030095", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3NGP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High resolution structure of alpha-spectrin SH3 domain mutant with a redesigned core"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M0U", "evidence_id": "EV-PDB-3M0U-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "3M0U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M0U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Hexagonal crystal obtained in sodium formate at pH 6.5."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M0T", "evidence_id": "EV-PDB-3M0T-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3M0T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M0T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 9."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M0R", "evidence_id": "EV-PDB-3M0R-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "3M0R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M0R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 6."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M0Q", "evidence_id": "EV-PDB-3M0Q-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "3M0Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M0Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 5."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3M0P", "evidence_id": "EV-PDB-3M0P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "3M0P", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3M0P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 4."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LJ3", "evidence_id": "EV-PDB-2LJ3-1", "mappings": [], "molecule_id": "P07751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LJ3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LJ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "PFBD: High-throughput Strategy of Backbone fold Determination for small well-folded proteins in less than a day"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": 30.0}, "construct": {"description": "Spectrin alpha chain, brain and P41 peptide chimera (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JMC", "evidence_id": "EV-PDB-2JMC-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2JMC", "doi": "10.1016/j.febslet.2007.01.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JMC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Chimer between Spc-SH3 and P41"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JMA", "evidence_id": "EV-PDB-2JMA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2JMA", "doi": "10.1186/1472-6807-7-22", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JMA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "R21A Spc-SH3:P41 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spectrin alpha chain, brain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F2X", "evidence_id": "EV-PDB-2F2X-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure titled as the SH3 domain; the UniProt entry covers the whole spectrin chain, so other repeats are excluded by title.", "rule": "sh3-structures-native", "state_id": "SH3-native", "who": "rule:sh3-structures-native"}], "molecule_id": "P07751", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "2F2X", "doi": "10.1002/prot.21284", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F2X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "alpha-spectrin SH3 domain R21G mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UYL", "evidence_id": "EV-PDB-1UYL-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "1UYL", "doi": "10.1016/J.CHEMBIOL.2004.03.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UYL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure-Activity Relationships in purine-based inhibitor binding to HSP90 isoforms"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PU0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UYH", "evidence_id": "EV-PDB-1UYH-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1UYH", "doi": "10.1016/J.CHEMBIOL.2004.03.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Hsp90-alpha with 9-Butyl-8-(2,5-dimethoxy-benzyl)-2-fluoro-9H-purin-6-ylamine"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PU8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UYD", "evidence_id": "EV-PDB-1UYD-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1UYD", "doi": "10.1016/J.CHEMBIOL.2004.03.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UYD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Hsp90-alpha with 9-Butyl-8-(2-chloro-3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PU7"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UYC", "evidence_id": "EV-PDB-1UYC-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1UYC", "doi": "10.1016/J.CHEMBIOL.2004.03.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UYC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Hsp90-alpha with 9-Butyl-8-(2,5-dimethoxy-benzyl)-9H-purin-6-ylamine"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PU3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UY6", "evidence_id": "EV-PDB-1UY6-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1UY6", "doi": "10.1016/J.CHEMBIOL.2004.03.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UY6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Hsp90-alpha with 9-Butyl-8-(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACY", "KOS", "MPD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "heat shock 90kDa protein 1, alpha; heat shock 90kD protein 1, alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OSF", "evidence_id": "EV-PDB-1OSF-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "1OSF", "doi": "10.1016/S1074-5521(03)00075-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OSF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Hsp90 in complex with 17-desmethoxy-17-N,N-Dimethylaminoethylamino-Geldanamycin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -165.15}, "construct": {"description": "PROTEIN (HEAT SHOCK PROTEIN 90) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BYQ", "evidence_id": "EV-PDB-1BYQ-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1BYQ", "doi": "10.1083/jcb.143.4.901", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BYQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HSP90 N-TERMINAL DOMAIN BOUND TO ADP-MG"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZZ6"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN, HSP90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WI6", "evidence_id": "EV-PDB-2WI6-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.18}, "provenance": {"deposit_id": "2WI6", "doi": "10.1021/JM900357Y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WI6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2KL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WI7", "evidence_id": "EV-PDB-2WI7-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "2WI7", "doi": "10.1021/JM900357Y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WI7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["XDK"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2XDK", "evidence_id": "EV-PDB-2XDK-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.97}, "provenance": {"deposit_id": "2XDK", "doi": "10.1021/JM100059D", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2XDK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of HSP90 with small molecule inhibitor bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "LGA", "MG", "MT0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2XDU", "evidence_id": "EV-PDB-2XDU-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.74}, "provenance": {"deposit_id": "2XDU", "doi": "10.1021/JM100059D", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2XDU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of HSP90 with small molecule inhibitor bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["819"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -171.75}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HHU", "evidence_id": "EV-PDB-3HHU-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.59}, "provenance": {"deposit_id": "3HHU", "doi": "10.1111/j.1747-0285.2009.00833.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HHU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human heat-shock protein 90 (HSP90) in complex with {4-[3-(2,4-dihydroxy-5-isopropyl-phenyl)-5-thioxo- 1,5-dihydro-[1,2,4]triazol-4-yl]-benzyl}-carbamic acid ethyl ester {ZK 2819}"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SD1"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -159.65}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MNR", "evidence_id": "EV-PDB-3MNR-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3MNR", "doi": "10.1016/j.chembiol.2010.04.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Benzamide SNX-1321 bound to Hsp90"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MEX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OW6", "evidence_id": "EV-PDB-3OW6-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3OW6", "doi": "10.1016/j.bmcl.2010.10.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OW6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HSP90 with N-Aryl-benzimidazolone I"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FU7", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.3, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3R4P", "evidence_id": "EV-PDB-3R4P-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3R4P", "doi": "10.1021/jm200128m", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3R4P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Optimization of potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitors of heat shock protein 90. identification of development candidate 2-amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["06J"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3R92", "evidence_id": "EV-PDB-3R92-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5801}, "provenance": {"deposit_id": "3R92", "doi": "10.1016/j.bmcl.2011.04.102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3R92"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3RP", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.3, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RLP", "evidence_id": "EV-PDB-3RLP-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3RLP", "doi": "10.1016/j.bmcl.2011.04.130", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RLP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3RQ", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.3, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RLQ", "evidence_id": "EV-PDB-3RLQ-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3RLQ", "doi": "10.1016/j.bmcl.2011.04.130", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RLQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5- carbonitrile"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3T0Z", "evidence_id": "EV-PDB-3T0Z-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.192}, "provenance": {"deposit_id": "3T0Z", "doi": "10.1093/abbs/gms001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3T0Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hsp90 N-terminal domain bound to ATP"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "HEAT SHOCK PROTEIN HSP 90-ALPHA (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4CGW", "evidence_id": "EV-PDB-4CGW-2", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.001}, "provenance": {"deposit_id": "4CGW", "doi": "10.1016/J.STR.2014.04.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4CGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Second TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J80", "evidence_id": "EV-PDB-5J80-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.17}, "provenance": {"deposit_id": "5J80", "doi": "10.1038/s41467-017-02258-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J80"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Apo Hsp90-alpha N-domain L107A mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6DL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J8U", "evidence_id": "EV-PDB-5J8U-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "5J8U", "doi": "10.1038/s41467-017-02258-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J8U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Hsp90-alpha N-domain L107A mutant in complex with 5-(2,4-Dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["70K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LNY", "evidence_id": "EV-PDB-5LNY-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.88}, "provenance": {"deposit_id": "5LNY", "doi": "10.1021/acs.jmedchem.8b00080", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LNY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HSP90 WITH indazole derivative"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6GPR", "evidence_id": "EV-PDB-6GPR-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "6GPR", "doi": "10.1016/j.bbapap.2018.09.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6GPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) in complex with cAMP"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PA7"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6B9A", "evidence_id": "EV-PDB-6B9A-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65381}, "provenance": {"deposit_id": "6B9A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6B9A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hsp90-alpha N-domain bound to NPCA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NEC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6B99", "evidence_id": "EV-PDB-6B99-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.60237722156}, "provenance": {"deposit_id": "6B99", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6B99"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hsp90-alpha N-domain bound to NECA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["Q2A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6U9A", "evidence_id": "EV-PDB-6U9A-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "6U9A", "doi": "10.1021/jacs.9b09684", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6U9A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hsp90a NTD K58R bound reversibly to sulfonyl fluoride 5"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "H9F", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DMC", "evidence_id": "EV-PDB-7DMC-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.34}, "provenance": {"deposit_id": "7DMC", "doi": "10.1016/j.bcp.2022.115376", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DMC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Dipyridamole binds to the N-terminal domain of human Hsp90A"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AW1"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HA4", "evidence_id": "EV-PDB-7HA4-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.61}, "provenance": {"deposit_id": "7HA4", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HA4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14240"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AW2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HA5", "evidence_id": "EV-PDB-7HA5-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "7HA5", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HA5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-3550"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AXP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HAH", "evidence_id": "EV-PDB-7HAH-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "7HAH", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HAH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-5160"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AX5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HAM", "evidence_id": "EV-PDB-7HAM-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.77}, "provenance": {"deposit_id": "7HAM", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HAM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14242"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AYP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HBY", "evidence_id": "EV-PDB-7HBY-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82}, "provenance": {"deposit_id": "7HBY", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 9R-0342"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AXR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HBT", "evidence_id": "EV-PDB-7HBT-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.38}, "provenance": {"deposit_id": "7HBT", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HBT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-3621"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6RO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HB5", "evidence_id": "EV-PDB-7HB5-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "7HB5", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13078"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AXV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HB4", "evidence_id": "EV-PDB-7HB4-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.87}, "provenance": {"deposit_id": "7HB4", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14472"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AYU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Heat shock protein HSP 90-alpha (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7HAQ", "evidence_id": "EV-PDB-7HAQ-1", "mappings": [], "molecule_id": "P07900", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "7HAQ", "doi": "10.1107/S2052252524012247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7HAQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13428"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MMA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FimH PROTEIN (chains B,D,F,H,J,L,N,P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KIU", "evidence_id": "EV-PDB-1KIU-2", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "1KIU", "doi": "10.1046/j.1365-2958.2002.02915.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KIU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH adhesin Q133N mutant-FimC chaperone complex with methyl-alpha-D-mannose"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MAN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH PROTEIN (chains B,D,F,H,J,L,N,P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KLF", "evidence_id": "EV-PDB-1KLF-2", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "1KLF", "doi": "10.1046/j.1365-2958.2002.02915.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KLF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": -100.15}, "construct": {"description": "MANNOSE-SPECIFIC ADHESIN FIMH (chains B,D,F,H,J,L,N,P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QUN", "evidence_id": "EV-PDB-1QUN-2", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1QUN", "doi": "10.1126/science.285.5430.1061", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QUN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAC", "DEG", "MPD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FimH protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TR7", "evidence_id": "EV-PDB-1TR7-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1TR7", "doi": "10.1111/j.1365-2958.2004.04415.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TR7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH adhesin receptor binding domain from uropathogenic E. coli"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FimH protein (chains H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZE3", "evidence_id": "EV-PDB-1ZE3-2", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "1ZE3", "doi": "10.1038/sj.emboj.7600693", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZE3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the Ternary Complex of FIMD (N-Terminal Domain) with FIMC and the Pilin Domain of FIMH"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "SO4", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN FIMH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2VCO", "evidence_id": "EV-PDB-2VCO-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2VCO", "doi": "10.1371/JOURNAL.PONE.0002040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2VCO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the fimbrial adhesin FimH in complex with its high-mannose epitope"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Type 1 fimbrial adhesin (chains A,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RFZ", "evidence_id": "EV-PDB-3RFZ-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "3RFZ", "doi": "10.1038/nature10109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RFZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BWG", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN FIMH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ZL1", "evidence_id": "EV-PDB-3ZL1-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.551}, "provenance": {"deposit_id": "3ZL1", "doi": "10.1021/JM400723N", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ZL1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A thiazolyl-mannoside bound to FimH, monoclinic space group"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HNV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4ATT", "evidence_id": "EV-PDB-4ATT-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.251}, "provenance": {"deposit_id": "4ATT", "doi": "10.1021/ML400269V", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4ATT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl para methoxy phenyl"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HNW"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AUJ", "evidence_id": "EV-PDB-4AUJ-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.527}, "provenance": {"deposit_id": "4AUJ", "doi": "10.1021/ML400269V", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AUJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to para hydroxypropargyl phenyl"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HNV", "NI", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AV0", "evidence_id": "EV-PDB-4AV0-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.099}, "provenance": {"deposit_id": "4AV0", "doi": "10.1021/BI300251R", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AV0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the FimH lectin domain in the trigonal space group, in complex with a methoxy phenyl propynyl alpha-D-mannoside at 2.1 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FYZ", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AV5", "evidence_id": "EV-PDB-4AV5-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "4AV5", "doi": "10.1021/BI300251R", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AV5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a triclinic crystal of the FimH lectin domain in complex with a propynyl biphenyl alpha-D-mannoside, at 1.4 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "SO4", "XNS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AVI", "evidence_id": "EV-PDB-4AVI-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "4AVI", "doi": "10.1021/BI300251R", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AVI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the FimH lectin domain in the trigonal space group, in complex with a methyl ester octyl alpha-D-mannoside at 2.4 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CWX", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN FIMH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4CSS", "evidence_id": "EV-PDB-4CSS-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.069}, "provenance": {"deposit_id": "4CSS", "doi": "10.1021/JM501524Q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4CSS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CWK"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN FIMH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4CST", "evidence_id": "EV-PDB-4CST-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "4CST", "doi": "10.1021/JM501524Q", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4CST"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with 3'-Chloro-4'-(alpha-D-mannopyranosyloxy)-biphenyl-4-carbonitrile"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4J3O", "evidence_id": "EV-PDB-4J3O-2", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "4J3O", "doi": "10.1038/nature12007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4J3O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3XJ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X5P", "evidence_id": "EV-PDB-4X5P-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.997}, "provenance": {"deposit_id": "4X5P", "doi": "10.1002/cbic.201402714", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X5P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with a benzoyl-amidophenyl alpha-D-mannopyranoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3XN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X5Q", "evidence_id": "EV-PDB-4X5Q-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.12}, "provenance": {"deposit_id": "4X5Q", "doi": "10.1002/cbic.201402714", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X5Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with 5-nitro-indolinylphenyl alpha-D-mannopyranoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3XO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X5R", "evidence_id": "EV-PDB-4X5R-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "4X5R", "doi": "10.1002/cbic.201402714", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X5R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with a squaryl-phenyl alpha-D-mannopyranoside derivative"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["KGM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XO8", "evidence_id": "EV-PDB-4XO8-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.698}, "provenance": {"deposit_id": "4XO8", "doi": "10.1038/ncomms10738", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XO8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the FimH lectin domain from E.coli K12 in complex with heptyl alpha-D-mannopyrannoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XO9", "evidence_id": "EV-PDB-4XO9-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.14}, "provenance": {"deposit_id": "4XO9", "doi": "10.1038/ncomms10738", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a FimH*DsG complex from E.coli K12 in space group C2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3X8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X50", "evidence_id": "EV-PDB-4X50-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4X50", "doi": "10.1002/cbic.201402714", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X50"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with biphenyl alpha-D-mannopyranoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "KGM", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LOV", "evidence_id": "EV-PDB-4LOV-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4LOV", "doi": "10.1021/jm401666c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with Heptylmannoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FVQ", "NI", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AVK", "evidence_id": "EV-PDB-4AVK-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "4AVK", "doi": "10.1021/BI300251R", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AVK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of trigonal FimH lectin domain crystal soaked with an alpha- D-mannoside O-linked to propynyl pyridine at 2.4A resolution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FK9", "NI", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AVH", "evidence_id": "EV-PDB-4AVH-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.105}, "provenance": {"deposit_id": "4AVH", "doi": "10.1021/BI300251R", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AVH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the FimH lectin domain in the trigonal space group, in complex with a thioalkyl alpha-D-mannoside at 2.1 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FVQ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AV4", "evidence_id": "EV-PDB-4AV4-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "4AV4", "doi": "10.1021/BI300251R", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AV4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl pyridine"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DEG", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FIMH PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UWF", "evidence_id": "EV-PDB-1UWF-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "1UWF", "doi": "10.1111/J.1365-2958.2004.04415.X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UWF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MCA", "evidence_id": "EV-PDB-5MCA-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.604}, "provenance": {"deposit_id": "5MCA", "doi": "10.1074/jbc.M117.802942", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MCA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH-LD R60P variant in the apo state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "XKA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MTS", "evidence_id": "EV-PDB-5MTS-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5MTS", "doi": "10.1002/cmdc.201700061", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MTS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex of FimH lectin with a TazMan (thiazolylaminomannosides) family member known as potent anti-adhesive agent at 2.6 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AH2"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Protein FimH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MUC", "evidence_id": "EV-PDB-5MUC-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5MUC", "doi": "10.1002/chem.201802599", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MUC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6E14", "evidence_id": "EV-PDB-6E14-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "6E14", "doi": "10.1038/s41586-018-0587-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6E14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6E15", "evidence_id": "EV-PDB-6E15-5", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.1}, "provenance": {"deposit_id": "6E15", "doi": "10.1038/s41586-018-0587-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6E15"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EJK", "EPE", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6G2R", "evidence_id": "EV-PDB-6G2R-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "6G2R", "doi": "10.1002/cmdc.201900051", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6G2R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with a tetraflourinated biphenyl alpha D-mannoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EJN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6G2S", "evidence_id": "EV-PDB-6G2S-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6G2S", "doi": "10.1002/cmdc.201900051", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6G2S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FimH in complex with a pentaflourinated biphenyl alpha D-mannoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6GTX", "evidence_id": "EV-PDB-6GTX-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6GTX", "doi": "10.1021/jacs.8b10736", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6GTX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the FimH lectin domain from E.coli K12 in complex with the dimannoside Man(alpha1-2)Man"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-6)-methyl alpha-D-mannopyranoside"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6GTY", "evidence_id": "EV-PDB-6GTY-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "6GTY", "doi": "10.1021/jacs.8b10736", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6GTY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the FimH lectin domain from E.coli K12 in complex with the dimannoside Man(alpha1-6)Man"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HP6", "MAN", "TA5", "branched: Cycloheptakis-(1-4)-(alpha-D-glucopyranose)"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FimH (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YHW", "evidence_id": "EV-PDB-6YHW-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.962}, "provenance": {"deposit_id": "6YHW", "doi": "10.1002/cbic.201600018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YHW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Co-crystals in the P212121 space group, of a beta-cyclodextrin spacered by triazole heptyl from alpha-D-mannose, with FimH lectin at 2.00 A resolution."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "SBQ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7AYN", "evidence_id": "EV-PDB-7AYN-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.42}, "provenance": {"deposit_id": "7AYN", "doi": "10.1016/j.ejmech.2020.113093", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7AYN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the lectin domain of the FimH variant Arg98Ala, in complex with Methyl 3-chloro-4-D-mannopyranosyloxy-3-biphenylcarboxylate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "SO4", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BHD", "evidence_id": "EV-PDB-7BHD-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "7BHD", "doi": "10.1016/j.jbc.2023.104627", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BHD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "SO4", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FimH (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QUO", "evidence_id": "EV-PDB-7QUO-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7QUO", "doi": "10.1016/j.jbc.2023.104627", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QUO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH lectin domain in complex with oligomannose-6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FimH,F1C putative fimbrial adhesin fusion (chains H,N)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SZO", "evidence_id": "EV-PDB-7SZO-4", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7SZO", "doi": "10.1016/j.jmb.2022.167681", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SZO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a bacterial fimbrial tip containing FocH"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["RLO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BVD", "evidence_id": "EV-PDB-8BVD-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.995}, "provenance": {"deposit_id": "8BVD", "doi": "10.3390/pharmaceutics15020527", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BVD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH lectin domain in complex with mannose C-linked to quinoline"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "SO4", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BXY", "evidence_id": "EV-PDB-8BXY-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "8BXY", "doi": "10.1016/j.jbc.2023.104627", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "SO4", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BY3", "evidence_id": "EV-PDB-8BY3-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.186}, "provenance": {"deposit_id": "8BY3", "doi": "10.1016/j.jbc.2023.104627", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BY3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FimH lectin domain in complex with oligomannose-6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin,Protein FimG (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V3J", "evidence_id": "EV-PDB-8V3J-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.898}, "provenance": {"deposit_id": "8V3J", "doi": "10.1371/journal.ppat.1012325", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V3J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure-Based Engineering of a Highly Immunogenic, Conformationally Stabilized FimH Antigen for a Urinary Tract Infection Vaccine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin FimH, Donor strand complemented with FimG peptide 'triple mutant' (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V93", "evidence_id": "EV-PDB-8V93-4", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "8V93", "doi": "10.1371/journal.ppat.1012325", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V93"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of E. coli FimH lectin domain bound to Fabs 329-2 and 454-3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BOG", "evidence_id": "EV-PDB-9BOG-4", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.99}, "provenance": {"deposit_id": "9BOG", "doi": "10.1073/pnas.2410594121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BOG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural basis for adhesin secretion by the outer-membrane usher in type 1 pili"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbiral adhesin FimH (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CCS", "evidence_id": "EV-PDB-9CCS-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.17}, "provenance": {"deposit_id": "9CCS", "doi": "10.1126/sciadv.adw0698", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CCS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM Structure of Escherichia coli FimCH in complex with 2H04 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbiral adhesin FimH (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CCT", "evidence_id": "EV-PDB-9CCT-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "9CCT", "doi": "10.1126/sciadv.adw0698", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CCT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM Structure of Escherichia coli FimCH in complex with B7 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbiral adhesin FimH (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CCU", "evidence_id": "EV-PDB-9CCU-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9CCU", "doi": "10.1126/sciadv.adw0698", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CCU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM Structure of Escherichia coli FimCH in complex with F7 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbiral adhesin FimH (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CCW", "evidence_id": "EV-PDB-9CCW-1", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.69}, "provenance": {"deposit_id": "9CCW", "doi": "10.1126/sciadv.adw0698", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CCW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM Structure of Escherichia coli FimCH in complex with 2C07 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin FimH, Donor strand complemented with FimG peptide 'triple mutant' (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D6F", "evidence_id": "EV-PDB-9D6F-5", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.24}, "provenance": {"deposit_id": "9D6F", "doi": "10.1371/journal.ppat.1012325", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D6F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of E. coli FimH lectin domain bound to Fabs 440-2 and 454-3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Type 1 fimbrin D-mannose specific adhesin (chains H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FY9", "evidence_id": "EV-PDB-9FY9-5", "mappings": [], "molecule_id": "P08191", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9FY9", "doi": "10.1038/s41467-025-60325-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FY9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the type 1 chaperone-usher pilus FimD-tip complex (FimDHGFC) - Conformer 1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "TBA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "VOLTAGE-GATED POTASSIUM CHANNEL (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1J95", "evidence_id": "EV-PDB-1J95-1", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1J95", "doi": "10.1038/35079500", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1J95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KCSA potassium channel with TBA (tetrabutylammonium) and potassium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -123.15}, "construct": {"description": "VOLTAGE-GATED POTASSIUM CHANNEL (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JQ2", "evidence_id": "EV-PDB-1JQ2-1", "mappings": [{"confidence": "medium", "justification": "Title describes an open or partially open gate.", "rule": "kcsa-open-title", "state_id": "KcsA-open-inactivated", "who": "rule:kcsa-open-title"}], "molecule_id": "P0A334", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1JQ2", "doi": "10.1038/nsb1001-883", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JQ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "POTASSIUM CHANNEL (KCSA) OPEN GATE MODEL"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 41.85}, "construct": {"description": "Voltage-gated potassium channel (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2A9H", "evidence_id": "EV-PDB-2A9H-1", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2A9H", "doi": "10.1021/bi051656d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2A9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structural studies of a potassium channel / charybdotoxin complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F09", "L2C", "TBA", "TL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2DWD", "evidence_id": "EV-PDB-2DWD-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "2DWD", "doi": "10.1016/j.jmb.2006.11.081", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2DWD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "crystal structure of KcsA-FAB-TBA complex in Tl+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F09", "L2C", "RB", "TBA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2DWE", "evidence_id": "EV-PDB-2DWE-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "2DWE", "doi": "10.1016/j.jmb.2006.11.081", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2DWE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of KcsA-FAB-TBA complex in Rb+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["B3H", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": null}, "construct": {"description": "KcsA Channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2H8P", "evidence_id": "EV-PDB-2H8P-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "2H8P", "doi": "10.1021/ja0631955", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2H8P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a K channel with an amide to ester substitution in the selectivity filter"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["B3H", "CS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "KCSA CHANNEL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2HG5", "evidence_id": "EV-PDB-2HG5-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "2HG5", "doi": "10.1021/ja0631955", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2HG5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "TBA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2HJF", "evidence_id": "EV-PDB-2HJF-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "2HJF", "doi": "10.1016/j.jmb.2006.09.069", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2HJF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Potassium channel kcsa-fab complex with tetrabutylammonium (TBA)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F09", "K", "L2C", "TBA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2HVJ", "evidence_id": "EV-PDB-2HVJ-3", "mappings": [{"confidence": "medium", "justification": "Title describes low K+ conditions, where the filter collapses.", "rule": "kcsa-low-k-title", "state_id": "KcsA-closed-collapsed", "who": "rule:kcsa-low-k-title"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "2HVJ", "doi": "10.1016/j.jmb.2006.11.081", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2HVJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of KcsA-Fab-TBA complex in low K+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F09", "K", "L2C", "TBA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2HVK", "evidence_id": "EV-PDB-2HVK-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2HVK", "doi": "10.1016/j.jmb.2006.11.081", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2HVK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "crystal structure of the KcsA-Fab-TBA complex in high K+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1EM", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2IH3", "evidence_id": "EV-PDB-2IH3-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "2IH3", "doi": "10.1126/science.1133415", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2IH3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ITC", "evidence_id": "EV-PDB-2ITC-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "2ITC", "doi": "10.1371/journal.pbio.0050121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ITC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Potassium Channel KcsA-Fab complex in Sodium Chloride"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ITD", "evidence_id": "EV-PDB-2ITD-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "2ITD", "doi": "10.1371/journal.pbio.0050121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ITD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Potassium Channel KcsA-Fab complex in Barium Chloride"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CO", "F09", "HP6", "K", "L2C", "TBA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "VOLTAGE-GATED POTASSIUM CHANNEL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JK5", "evidence_id": "EV-PDB-2JK5-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "2JK5", "doi": "10.1021/BI500525S", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JK5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Potassium Channel KcsA in complex with Tetrabutylammonium in high K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1EM", "F09", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2P7T", "evidence_id": "EV-PDB-2P7T-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "2P7T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2P7T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of KcsA mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2QTO", "evidence_id": "EV-PDB-2QTO-1", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.201}, "provenance": {"deposit_id": "2QTO", "doi": "10.1016/j.str.2007.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2QTO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "An anisotropic model for potassium channel KcsA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CO", "DGA", "F09", "HX0", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "VOLTAGE-GATED POTASSIUM CHANNEL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2W0F", "evidence_id": "EV-PDB-2W0F-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "2W0F", "doi": "10.1021/BI500525S", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2W0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Potassium Channel KcsA-Fab Complex with Tetraoctylammonium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3F5W", "evidence_id": "EV-PDB-3F5W-3", "mappings": [{"confidence": "high", "justification": "Title: open-inactivated state, 32 Å opening at T112.", "rule": "curator_assignment", "state_id": "KcsA-open-inactivated", "who": "curator:draft (unreviewed)"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "3F5W", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3F5W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA Potassium channel in the open-inactivated state with 32 A opening at T112"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3F7V", "evidence_id": "EV-PDB-3F7V-3", "mappings": [{"confidence": "medium", "justification": "Title describes an open or partially open gate.", "rule": "kcsa-open-title", "state_id": "KcsA-open-inactivated", "who": "rule:kcsa-open-title"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "3F7V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3F7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA Potassium channel in the open-inactivated state with 23 A opening at T112"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Voltage-gated potassium channel (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FB5", "evidence_id": "EV-PDB-3FB5-3", "mappings": [{"confidence": "medium", "justification": "Title describes an open or partially open gate.", "rule": "kcsa-open-title", "state_id": "KcsA-open-inactivated", "who": "rule:kcsa-open-title"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "3FB5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA potassium channel in the partially open state with 14.5 A opening at T112"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DGA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LCU", "evidence_id": "EV-PDB-4LCU-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.752}, "provenance": {"deposit_id": "4LCU", "doi": "10.1085/jgp.201311057", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LCU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of KcsA with E118A mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DGA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MSW", "evidence_id": "EV-PDB-4MSW-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.06}, "provenance": {"deposit_id": "4MSW", "doi": "10.1073/pnas.1314356110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MSW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Y78 ester mutant of KcsA in high K+"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DGA", "F09", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EBL", "evidence_id": "EV-PDB-5EBL-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5EBL", "doi": "10.1016/j.str.2016.02.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EBL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA T75G in the Conductive State"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DGA", "F09", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EBM", "evidence_id": "EV-PDB-5EBM-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "5EBM", "doi": "10.1016/j.str.2016.02.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EBM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA T75G mutant in the nonconductive state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DGA", "F09", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EBW", "evidence_id": "EV-PDB-5EBW-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5EBW", "doi": "10.1016/j.str.2016.02.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EBW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA with G77ester mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DGA", "F09", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EC2", "evidence_id": "EV-PDB-5EC2-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5EC2", "doi": "10.1016/j.str.2016.02.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EC2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA with V76ester+G77dA mutations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5J9P", "evidence_id": "EV-PDB-5J9P-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "5J9P", "doi": "10.1021/acs.biochem.6b00488", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5J9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "KcsA in vitro"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DGA", "F09", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PA0", "evidence_id": "EV-PDB-6PA0-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "6PA0", "doi": "10.1073/pnas.1901888116", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PA0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the G77A mutant in Sodium Chloride"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6W0A", "evidence_id": "EV-PDB-6W0A-3", "mappings": [{"confidence": "medium", "justification": "Title describes an open or partially open gate.", "rule": "kcsa-open-title", "state_id": "KcsA-open-inactivated", "who": "rule:kcsa-open-title"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.237}, "provenance": {"deposit_id": "6W0A", "doi": "10.1016/j.jmb.2020.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6W0A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Open-gate KcsA soaked in 1 mM BaCl2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6W0C", "evidence_id": "EV-PDB-6W0C-3", "mappings": [{"confidence": "medium", "justification": "Title describes an open or partially open gate.", "rule": "kcsa-open-title", "state_id": "KcsA-open-inactivated", "who": "rule:kcsa-open-title"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.556}, "provenance": {"deposit_id": "6W0C", "doi": "10.1016/j.jmb.2020.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6W0C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Open-gate KcsA soaked in 4 mM BaCl2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6W0D", "evidence_id": "EV-PDB-6W0D-3", "mappings": [{"confidence": "medium", "justification": "Title describes an open or partially open gate.", "rule": "kcsa-open-title", "state_id": "KcsA-open-inactivated", "who": "rule:kcsa-open-title"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.639}, "provenance": {"deposit_id": "6W0D", "doi": "10.1016/j.jmb.2020.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6W0D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Open-gate KcsA soaked in 5 mM BaCl2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6W0E", "evidence_id": "EV-PDB-6W0E-3", "mappings": [{"confidence": "medium", "justification": "Title describes an open or partially open gate.", "rule": "kcsa-open-title", "state_id": "KcsA-open-inactivated", "who": "rule:kcsa-open-title"}], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.512}, "provenance": {"deposit_id": "6W0E", "doi": "10.1016/j.jmb.2020.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6W0E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Open-gate KcsA soaked in 10 mM BaCl2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -175.15}, "construct": {"description": "pH-gated potassium channel KcsA (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6W0F", "evidence_id": "EV-PDB-6W0F-3", "mappings": [], "molecule_id": "P0A334", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "6W0F", "doi": "10.1016/j.jmb.2020.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6W0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Closed-gate KcsA soaked in 0mM KCl/5mM BaCl2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chaperone protein DnaK (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N6J", "evidence_id": "EV-PDB-7N6J-1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "7N6J", "doi": "10.1073/pnas.2016962118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N6J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RKQSTIALALLPLLFTPRR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chaperone protein DnaK (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N6M", "evidence_id": "EV-PDB-7N6M-1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82}, "provenance": {"deposit_id": "7N6M", "doi": "10.1073/pnas.2016962118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N6M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RQKPLLGLSR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "GOL", "K", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chaperone protein DnaK (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RAX", "evidence_id": "EV-PDB-7RAX-1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.41}, "provenance": {"deposit_id": "7RAX", "doi": "10.1016/j.molcel.2021.07.039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RAX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ATP-binding state of the nucleotide-binding domain of Hsp70 DnaK mutant T199A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "P0A6Y8 (chains A)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A2I", "evidence_id": "EV-PDB-9A2I-1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A2I", "doi": "10.1038/s41587-023-01704-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A2I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Model of E. coli DnaK by in-cell photo-crosslinking MS and deep learning"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chaperone protein DnaK (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N6K", "evidence_id": "EV-PDB-7N6K-1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "7N6K", "doi": "10.1073/pnas.2016962118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RALALLPLSR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "GOL", "MG", "PDO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chaperone protein DnaK fused with substrate peptide (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KRU", "evidence_id": "EV-PDB-7KRU-1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82}, "provenance": {"deposit_id": "7KRU", "doi": "10.1016/j.molcel.2021.07.039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KRU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Stimulating state of a truncated Hsp70 DnaK fused with a substrate peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chaperone protein DnaK (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JN9", "evidence_id": "EV-PDB-7JN9-1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7JN9", "doi": "10.1073/pnas.2016962118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JN9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide QEHTGSQLRIAAYGP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=27392", "evidence_id": "EV-BMRB-27392", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr27392", "doi": "10.13018/BMR27392", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=27392"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "E.Coli DnaK Nucleotide Binding Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51802", "evidence_id": "EV-BMRB-51802", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51802", "doi": "10.13018/BMR51802", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51802"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone assignment of DnaK C-terminal alpha-helical lid with C-IDR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 606-638; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/10048327", "evidence_id": "EV-DISPROT-DP02985r001", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 33}, "provenance": {"deposit_id": "DP02985r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02985"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP02985: disorder, residues 606-638"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-638", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P0A6Y8", "evidence_id": "EV-AFDB-AF-P0A6Y8-F1", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 92.25}, "provenance": {"deposit_id": "AF-P0A6Y8-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P0A6Y8"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P0A6Y8-F1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1BPR; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A004W/overview", "evidence_id": "EV-MDDB-A004W", "mappings": [], "molecule_id": "P0A6Y8", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A004W", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A004W/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1BPR"}
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{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-4B9Q-1"], "file": "models/P0A6Y8/DnaK-ATP-docked.cif", "format": "mmCIF", "model_id": "DnaK-ATP-docked-cif", "molecule_id": "P0A6Y8", "provenance": {"deposit_id": "4B9Q", "doi": "10.1016/J.MOLCEL.2012.09.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/4B9Q.cif"}, "record_type": "model", "state_id": "DnaK-ATP-docked"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-4B9Q-1"], "file": "models/P0A6Y8/DnaK-ATP-docked.pdb", "format": "PDB", "model_id": "DnaK-ATP-docked-pdb", "molecule_id": "P0A6Y8", "provenance": {"deposit_id": "4B9Q", "doi": "10.1016/J.MOLCEL.2012.09.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/4B9Q.pdb"}, "record_type": "model", "state_id": "DnaK-ATP-docked"}
{"components": [], "domains": [{"end": 158, "name": "DHFR", "start": 1}], "gene": "folA", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P0ABQ4"}, "ligands": ["NADP(+)", "substrate"], "modifications": [], "molecule_id": "P0ABQ4", "molecule_type": "protein", "name": "Dihydrofolate reductase", "organism": {"name": "Escherichia coli (strain K12)", "taxon_id": 83333}, "provenance": {"deposit_id": "P0ABQ4", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0ABQ4/entry"}, "record_type": "molecule", "sequence": "MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR", "sequence_length": 159}
{"assumptions": [], "basis": "observed", "description": "Met20 loop closed over the bound folate and NADP+, a model of the Michaelis complex, as in 1RX2.", "family_label": null, "molecule_id": "P0ABQ4", "name": "closed (Met20 loop closed over folate and NADP+)", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P0ABQ4.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P0ABQ4.yaml"}, "record_type": "state", "representative_model": "DHFR-closed-cif", "secondary_structure": null, "state_id": "DHFR-closed", "status": "draft"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DRA", "evidence_id": "EV-PDB-1DRA-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1DRA", "doi": "10.1021/bi00222a028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DRA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "DZF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DYH", "evidence_id": "EV-PDB-1DYH-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1DYH", "doi": "10.1021/bi00008a039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2DRC", "evidence_id": "EV-PDB-2DRC-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2DRC", "doi": "10.1021/bi00110a011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2DRC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K74", "evidence_id": "EV-PDB-3K74-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "3K74", "doi": "10.1016/j.jmb.2011.01.017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K74"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Disruption of protein dynamics by an allosteric effector antibody"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["817", "MN", "NDP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ANO", "evidence_id": "EV-PDB-2ANO-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "2ANO", "doi": "10.1021/jm060570v", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ANO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RX8", "evidence_id": "EV-PDB-1RX8-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1RX8", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RX8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RX7", "evidence_id": "EV-PDB-1RX7-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1RX7", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DDF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RX5", "evidence_id": "EV-PDB-1RX5-1", "mappings": [{"confidence": "medium", "justification": "Product analogue 5,10-dideazatetrahydrofolate (DDF) bound: occluded in E. coli DHFR.", "rule": "dhfr-ddthf-occluded", "state_id": "DHFR-occluded", "who": "rule:dhfr-ddthf-occluded"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1RX5", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RX2", "evidence_id": "EV-PDB-1RX2-1", "mappings": [{"confidence": "medium", "justification": "Folate and NADP+ complex; closed in Sawaya and Kraut (1997). Confirm.", "rule": "curator_assignment", "state_id": "DHFR-closed", "who": "curator:draft (unreviewed)"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1RX2", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RX2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MTX", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RH3", "evidence_id": "EV-PDB-1RH3-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "1RH3", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RH3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RG7", "evidence_id": "EV-PDB-1RG7-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1RG7", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RG7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RD7", "evidence_id": "EV-PDB-1RD7-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1RD7", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RD7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DDF", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RC4", "evidence_id": "EV-PDB-1RC4-1", "mappings": [{"confidence": "medium", "justification": "Product analogue 5,10-dideazatetrahydrofolate (DDF) bound: occluded in E. coli DHFR.", "rule": "dhfr-ddthf-occluded", "state_id": "DHFR-occluded", "who": "rule:dhfr-ddthf-occluded"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1RC4", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MTX", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RB3", "evidence_id": "EV-PDB-1RB3-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1RB3", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RB3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RB2", "evidence_id": "EV-PDB-1RB2-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1RB2", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RB2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RA9", "evidence_id": "EV-PDB-1RA9-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "1RA9", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RA9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATR", "FOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RA8", "evidence_id": "EV-PDB-1RA8-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1RA8", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RA8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 2-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "MTX", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RA3", "evidence_id": "EV-PDB-1RA3-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1RA3", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RA3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1RA1", "evidence_id": "EV-PDB-1RA1-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1RA1", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1RA1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "EOH", "FFO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JOM", "evidence_id": "EV-PDB-1JOM-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1JOM", "doi": "10.1021/bi960028g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JOM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "FFO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JOL", "evidence_id": "EV-PDB-1JOL-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "1JOL", "doi": "10.1021/bi960028g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JOL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "DDF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DYJ", "evidence_id": "EV-PDB-1DYJ-1", "mappings": [{"confidence": "medium", "justification": "Product analogue 5,10-dideazatetrahydrofolate (DDF) bound: occluded in E. coli DHFR.", "rule": "dhfr-ddthf-occluded", "state_id": "DHFR-occluded", "who": "rule:dhfr-ddthf-occluded"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1DYJ", "doi": "10.1021/bi00008a039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "FOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DYI", "evidence_id": "EV-PDB-1DYI-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1DYI", "doi": "10.1021/bi00008a039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DYI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DRH", "evidence_id": "EV-PDB-1DRH-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1DRH", "doi": "10.1021/bi00008a039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DRH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MTX", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DRE", "evidence_id": "EV-PDB-1DRE-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1DRE", "doi": "10.1021/bi962337c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DRE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "EOH", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DRB", "evidence_id": "EV-PDB-1DRB-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "1DRB", "doi": "10.1021/bi00222a028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DRB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DHJ", "evidence_id": "EV-PDB-1DHJ-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1DHJ", "doi": "10.1073/pnas.90.24.11753", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DHJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LONG-RANGE STRUCTURAL EFFECTS IN A SECOND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE REDUCTASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DHI", "evidence_id": "EV-PDB-1DHI-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1DHI", "doi": "10.1073/pnas.90.24.11753", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DHI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LONG-RANGE STRUCTURAL EFFECTS IN A SECOND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE REDUCTASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DDS", "evidence_id": "EV-PDB-1DDS-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1DDS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DDS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MTX", "URE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DDR", "evidence_id": "EV-PDB-1DDR-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "1DDR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MOLECULE: DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND UREA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/45PC", "evidence_id": "EV-PDB-45PC-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.85}, "provenance": {"deposit_id": "45PC", "doi": "10.64898/2026.09.17.752399", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/45PC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "6-conformation model of Escherichia coli dihydrofolate reductase at 100K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DFR", "evidence_id": "EV-PDB-4DFR-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4DFR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DFR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EJ1", "evidence_id": "EV-PDB-4EJ1-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "4EJ1", "doi": "10.1016/j.bbapap.2013.07.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EJ1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Binding of Nb113 camelid antibody fragment with the binary DHFR:folate complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4FHB", "evidence_id": "EV-PDB-4FHB-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "4FHB", "doi": "10.1016/j.bbapap.2013.07.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4FHB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MTX", "NDP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GH8", "evidence_id": "EV-PDB-4GH8-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "4GH8", "doi": "10.1073/pnas.1307130110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GH8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a 'humanized' E. coli dihydrofolate reductase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I13", "evidence_id": "EV-PDB-4I13-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "4I13", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I13"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody ca1697 binding to the DHFR.folate binary complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NX7", "evidence_id": "EV-PDB-4NX7-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "4NX7", "doi": "10.1073/pnas.1323440111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "single cryogenic temperature model of DHFR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DHF", "MN", "NDP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PDJ", "evidence_id": "EV-PDB-4PDJ-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.599}, "provenance": {"deposit_id": "4PDJ", "doi": "10.1073/pnas.1415856111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Neutron crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X5F", "evidence_id": "EV-PDB-4X5F-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4X5F", "doi": "10.1107/S2059798318009397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X5F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ecDHFR complexed with folate and NADP+ at 0.1 MPa"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X5G", "evidence_id": "EV-PDB-4X5G-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "4X5G", "doi": "10.1107/S2059798318009397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X5G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ecDHFR complexed with folate and NADP+ at 270 MPa"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X5H", "evidence_id": "EV-PDB-4X5H-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "4X5H", "doi": "10.1107/S2059798318009397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X5H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ecDHFR complexed with folate and NADP+ at 500 MPa"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BME", "FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X5J", "evidence_id": "EV-PDB-4X5J-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "4X5J", "doi": "10.1107/S2059798318009397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X5J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ecDHFR complexed with folate and NADP+ at 750 MPa"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DDF", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5CC9", "evidence_id": "EV-PDB-5CC9-1", "mappings": [{"confidence": "medium", "justification": "Product analogue 5,10-dideazatetrahydrofolate (DDF) bound: occluded in E. coli DHFR.", "rule": "dhfr-ddthf-occluded", "state_id": "DHFR-occluded", "who": "rule:dhfr-ddthf-occluded"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.199}, "provenance": {"deposit_id": "5CC9", "doi": "10.1021/jacs.5b05707", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5CC9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "L28F E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DDF", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5CCC", "evidence_id": "EV-PDB-5CCC-1", "mappings": [{"confidence": "medium", "justification": "Product analogue 5,10-dideazatetrahydrofolate (DDF) bound: occluded in E. coli DHFR.", "rule": "dhfr-ddthf-occluded", "state_id": "DHFR-occluded", "who": "rule:dhfr-ddthf-occluded"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "5CCC", "doi": "10.1021/jacs.5b05707", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5CCC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "wild-type E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DFR", "evidence_id": "EV-PDB-5DFR-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5DFR", "doi": "10.1021/bi00222a028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DFR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "FOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EAJ", "evidence_id": "EV-PDB-5EAJ-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.701}, "provenance": {"deposit_id": "5EAJ", "doi": "10.1021/acs.biochem.8b00424", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EAJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of DHFR in 0% Isopropanol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -3.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5SSS", "evidence_id": "EV-PDB-5SSS-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.14}, "provenance": {"deposit_id": "5SSS", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5SSS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 270 K (crystal 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -3.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5SST", "evidence_id": "EV-PDB-5SST-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.07}, "provenance": {"deposit_id": "5SST", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5SST"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 270 K (crystal 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -3.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5SSW", "evidence_id": "EV-PDB-5SSW-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.06}, "provenance": {"deposit_id": "5SSW", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5SSW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 270 K (multi-crystal)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5Z6M", "evidence_id": "EV-PDB-5Z6M-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.202}, "provenance": {"deposit_id": "5Z6M", "doi": "10.1107/S2059798318009397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5Z6M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-pressure Crystal Structure Analysis of M20 loop closed DHFR at 800 MPa"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MG", "THG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6CW7", "evidence_id": "EV-PDB-6CW7-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.03}, "provenance": {"deposit_id": "6CW7", "doi": "10.1038/s42003-018-0236-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6CW7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR product complex with (6S)-5,6,7,8-TETRAHYDROFOLATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "DHF", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6CXK", "evidence_id": "EV-PDB-6CXK-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.108}, "provenance": {"deposit_id": "6CXK", "doi": "10.1038/s42003-018-0236-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6CXK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR substrate complex with Dihydrofolate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DHF", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6CYV", "evidence_id": "EV-PDB-6CYV-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "6CYV", "doi": "10.1038/s42003-018-0236-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6CYV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR ternary complex with NADP and dihydrofolate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MG", "THG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MR9", "evidence_id": "EV-PDB-6MR9-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "6MR9", "doi": "10.1063/1.5086436", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MR9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR complex with a reaction intermediate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "DHF", "MG", "THG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MT8", "evidence_id": "EV-PDB-6MT8-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "6MT8", "doi": "10.1063/1.5086436", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MT8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR complex modeled with two ligand states"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "DHF", "MG", "THG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MTH", "evidence_id": "EV-PDB-6MTH-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "6MTH", "doi": "10.1063/1.5086436", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MTH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR complex modeled with three ligand states"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NDP", "PGE", "TOP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion,Dihydrofolate reductase,GFP-LAMA-F98 a GFP enhancer nanobody with cpDHFR insertion (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6RUL", "evidence_id": "EV-PDB-6RUL-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6RUL", "doi": "10.1038/s41592-020-0746-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6RUL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of GFP-LAMA-F98 - a GFP enhancer nanobody with cpDHFR insertion and TMP and NADPH"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DFR", "evidence_id": "EV-PDB-6DFR-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "6DFR", "doi": "10.1021/bi00465a018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DFR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5Z6K", "evidence_id": "EV-PDB-5Z6K-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.802}, "provenance": {"deposit_id": "5Z6K", "doi": "10.1107/S2059798318009397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5Z6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-pressure Crystal Structure Analysis of M20 loop closed DHFR at 400 MPa"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 23.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5Z6J", "evidence_id": "EV-PDB-5Z6J-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.803}, "provenance": {"deposit_id": "5Z6J", "doi": "10.1107/S2059798318009397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5Z6J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-pressure Crystal Structure Analysis of M20 loop closed DHFR at 220 MPa"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KJL", "evidence_id": "EV-PDB-4KJL-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.38}, "provenance": {"deposit_id": "4KJL", "doi": "10.1038/nmeth.2592", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KJL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room Temperature N23PPS148A DHFR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KJK", "evidence_id": "EV-PDB-4KJK-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.351}, "provenance": {"deposit_id": "4KJK", "doi": "10.1038/nmeth.2592", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KJK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room Temperature WT DHFR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KJJ", "evidence_id": "EV-PDB-4KJJ-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "4KJJ", "doi": "10.1038/nmeth.2592", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KJJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic WT DHFR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EIZ", "evidence_id": "EV-PDB-4EIZ-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "4EIZ", "doi": "10.1016/j.bbapap.2013.07.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EIZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Nb113 bound to apoDHFR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EIG", "evidence_id": "EV-PDB-4EIG-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "4EIG", "doi": "10.1016/j.bbapap.2013.07.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EIG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CA1698 camel antibody fragment in complex with DHFR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D49", "evidence_id": "EV-PDB-7D49-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.651}, "provenance": {"deposit_id": "7D49", "doi": "10.1021/acscatal.1c00417", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D49"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH4.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D4L", "evidence_id": "EV-PDB-7D4L-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "7D4L", "doi": "10.1021/acscatal.1c00417", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D4L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH7.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D4X", "evidence_id": "EV-PDB-7D4X-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.599}, "provenance": {"deposit_id": "7D4X", "doi": "10.1021/acscatal.1c00417", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D4X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH7.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D6G", "evidence_id": "EV-PDB-7D6G-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "7D6G", "doi": "10.1021/acscatal.1c00417", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D6G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Neutron crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH4.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["D4C", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7F3B", "evidence_id": "EV-PDB-7F3B-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "7F3B", "doi": "10.1016/j.ejmech.2021.113979", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7F3B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "cocrystallization of Escherichia coli dihydrofolate reductase (DHFR) and its pyrrolo[3,2-f]quinazoline inhibitor."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPL", "evidence_id": "EV-PDB-7FPL-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.17}, "provenance": {"deposit_id": "7FPL", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 280 K (crystal 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPM", "evidence_id": "EV-PDB-7FPM-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.04}, "provenance": {"deposit_id": "7FPM", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 280 K (crystal 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPN", "evidence_id": "EV-PDB-7FPN-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.04}, "provenance": {"deposit_id": "7FPN", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 280 K (crystal 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPO", "evidence_id": "EV-PDB-7FPO-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.06}, "provenance": {"deposit_id": "7FPO", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 280 K (crystal 4)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPP", "evidence_id": "EV-PDB-7FPP-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.03}, "provenance": {"deposit_id": "7FPP", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 280 K (crystal 5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPQ", "evidence_id": "EV-PDB-7FPQ-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.03}, "provenance": {"deposit_id": "7FPQ", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 280 K (multi-crystal)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPR", "evidence_id": "EV-PDB-7FPR-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.07}, "provenance": {"deposit_id": "7FPR", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 290 K (crystal 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPS", "evidence_id": "EV-PDB-7FPS-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.26}, "provenance": {"deposit_id": "7FPS", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 290 K (crystal 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPT", "evidence_id": "EV-PDB-7FPT-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.07}, "provenance": {"deposit_id": "7FPT", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 290 K (crystal 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPU", "evidence_id": "EV-PDB-7FPU-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.05}, "provenance": {"deposit_id": "7FPU", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 290 K (crystal 4)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPV", "evidence_id": "EV-PDB-7FPV-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.04}, "provenance": {"deposit_id": "7FPV", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 290 K (crystal 5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPW", "evidence_id": "EV-PDB-7FPW-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.04}, "provenance": {"deposit_id": "7FPW", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 290 K (multi-crystal)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPX", "evidence_id": "EV-PDB-7FPX-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.06}, "provenance": {"deposit_id": "7FPX", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 300 K (crystal 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPY", "evidence_id": "EV-PDB-7FPY-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.12}, "provenance": {"deposit_id": "7FPY", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 300 K (crystal 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FPZ", "evidence_id": "EV-PDB-7FPZ-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.32}, "provenance": {"deposit_id": "7FPZ", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FPZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 300 K (crystal 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ0", "evidence_id": "EV-PDB-7FQ0-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "7FQ0", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 300 K (crystal 4)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ1", "evidence_id": "EV-PDB-7FQ1-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.18}, "provenance": {"deposit_id": "7FQ1", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 300 K (crystal 5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ2", "evidence_id": "EV-PDB-7FQ2-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.07}, "provenance": {"deposit_id": "7FQ2", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 300 K (multi-crystal)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ3", "evidence_id": "EV-PDB-7FQ3-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "7FQ3", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 310 K (crystal 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ4", "evidence_id": "EV-PDB-7FQ4-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.33}, "provenance": {"deposit_id": "7FQ4", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 310 K (crystal 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ5", "evidence_id": "EV-PDB-7FQ5-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "7FQ5", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 310 K (crystal 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ6", "evidence_id": "EV-PDB-7FQ6-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.29}, "provenance": {"deposit_id": "7FQ6", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex at 310 K (multi-crystal)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ7", "evidence_id": "EV-PDB-7FQ7-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.1}, "provenance": {"deposit_id": "7FQ7", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 1, pass 1, 295 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ8", "evidence_id": "EV-PDB-7FQ8-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.21}, "provenance": {"deposit_id": "7FQ8", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 1, pass 2, 310 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQ9", "evidence_id": "EV-PDB-7FQ9-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.11}, "provenance": {"deposit_id": "7FQ9", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 1, pass 3, 295 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQA", "evidence_id": "EV-PDB-7FQA-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.08}, "provenance": {"deposit_id": "7FQA", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 1, pass 4, 280 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQB", "evidence_id": "EV-PDB-7FQB-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.14}, "provenance": {"deposit_id": "7FQB", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 1, pass 5, 295 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQC", "evidence_id": "EV-PDB-7FQC-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.18}, "provenance": {"deposit_id": "7FQC", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 2, pass 1, 295 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 6.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQD", "evidence_id": "EV-PDB-7FQD-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.17}, "provenance": {"deposit_id": "7FQD", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 2, pass 2, 280 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQE", "evidence_id": "EV-PDB-7FQE-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.18}, "provenance": {"deposit_id": "7FQE", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 2, pass 3, 295 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQF", "evidence_id": "EV-PDB-7FQF-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.23}, "provenance": {"deposit_id": "7FQF", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 2, pass 4, 310 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FQG", "evidence_id": "EV-PDB-7FQG-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.19}, "provenance": {"deposit_id": "7FQG", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FQG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DHFR:NADP+:FOL complex (crystal 2, pass 5, 295 K)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LVC", "evidence_id": "EV-PDB-7LVC-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "7LVC", "doi": "10.1107/S2059798322006799", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LVC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR by Native Mn,P,S-SAD at Room Temperature"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "ZM4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MQP", "evidence_id": "EV-PDB-7MQP-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "7MQP", "doi": "10.1038/s42003-022-03384-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MQP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli dihydrofolate reductase complexed with 4'-chloro-3'-(4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl)-[1,1'-biphenyl]-4-carboxamide (UCP1228)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ARG", "NAP", "SO4", "TOP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MYM", "evidence_id": "EV-PDB-7MYM-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "7MYM", "doi": "10.1038/s42003-022-03384-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM and NADPH"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "TOP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NAE", "evidence_id": "EV-PDB-7NAE-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "7NAE", "doi": "10.1038/s42003-022-03384-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NAE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["560", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7REB", "evidence_id": "EV-PDB-7REB-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.91}, "provenance": {"deposit_id": "7REB", "doi": "10.1038/s42003-022-03384-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7REB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli dihydrofolate reductase complexed with 5-(3-(7-(4-(aminomethyl)phenyl)benzo[d][1,3]dioxol-5-yl)but-1-yn-1-yl)-6-ethylpyrimidine-2,4-diamine (UCP1223)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "NAP", "R6F"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DAI", "evidence_id": "EV-PDB-8DAI-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.14}, "provenance": {"deposit_id": "8DAI", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DAI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR complex with NADP+ and 10-methylfolate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G4Z", "evidence_id": "EV-PDB-8G4Z-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8G4Z", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G4Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR complex with NADP+ and folate: EF-X off model by Laue diffraction (no electric field)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G50", "evidence_id": "EV-PDB-8G50-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8G50", "doi": "10.1073/pnas.2313192121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G50"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli DHFR complex with NADP+ and folate: EF-X excited state model by Laue diffraction (electric field along b axis; 8-fold extrapolation of structure factor differences)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DIHYDROFOLATE REDUCTASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DFR", "evidence_id": "EV-PDB-7DFR-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7DFR", "doi": "10.1021/bi00465a018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DFR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. THE NADP+ HOLOENZYME AND THE FOLATE(DOT)NADP+ TERNARY COMPLEX. SUBSTRATE BINDING AND A MODEL FOR THE TRANSITION STATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "sfGFP (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HCO", "evidence_id": "EV-PDB-8HCO-6", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "8HCO", "doi": "10.1038/s41594-023-01103-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HCO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Substrate-engaged TOM complex from yeast"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FOL", "MN", "NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UW0", "evidence_id": "EV-PDB-8UW0-1", "mappings": [{"confidence": "medium", "justification": "Folate with NADP+ bound: the Michaelis-complex mimic, closed in E. coli DHFR.", "rule": "dhfr-folate-nadp-closed", "state_id": "DHFR-closed", "who": "rule:dhfr-folate-nadp-closed"}], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.93}, "provenance": {"deposit_id": "8UW0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UW0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Escherichia coli DHFR bound to NADP+ and folate, 17.2 MGy dose"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG", "MTX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Dihydrofolate reductase (chains S)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V9R", "evidence_id": "EV-PDB-8V9R-2", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8V9R", "doi": "10.1038/s41467-024-53681-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V9R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Branched-Degron DHFR-ssrA Substrate Bound with MTX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Dihydrofolate reductase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VZ4", "evidence_id": "EV-PDB-8VZ4-1", "mappings": [], "molecule_id": "P0ABQ4", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.25}, "provenance": {"deposit_id": "8VZ4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VZ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "L54G Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=4802", "evidence_id": "EV-BMRB-4802", "mappings": [], "molecule_id": "P0ACF8", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr4802", "doi": "10.13018/BMR4802", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=4802"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H, 13C, and 15N sequential assignment of the triple labelled N-terminal domain of the Histone like Nucleoid Structuring protein (H-NS) from Salmonella typhimurium (first 64 residues of the protein)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5390", "evidence_id": "EV-BMRB-5390", "mappings": [], "molecule_id": "P0ACF8", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5390", "doi": "10.13018/BMR5390", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5390"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H,13C and 15N Chemical Shifts Assignments for the Oligomerization Domain of H-NS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1HNR; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A00JF/overview", "evidence_id": "EV-MDDB-A00JF", "mappings": [], "molecule_id": "P0ACF8", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A00JF", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A00JF/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1HNR"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CHEMOTAXIS PROTEIN CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1C4W", "evidence_id": "EV-PDB-1C4W-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "1C4W", "doi": "10.1021/bi9925524", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1C4W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.9 A STRUCTURE OF A-THIOPHOSPHONATE MODIFIED CHEY D57C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CEY", "evidence_id": "EV-PDB-1CEY-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1CEY", "doi": "10.1021/bi00201a022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CEY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "ASSIGNMENTS, SECONDARY STRUCTURE, GLOBAL FOLD, AND DYNAMICS OF CHEMOTAXIS Y PROTEIN USING THREE-AND FOUR-DIMENSIONAL HETERONUCLEAR (13C,15N) NMR SPECTROSCOPY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CHN", "evidence_id": "EV-PDB-1CHN-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.76}, "provenance": {"deposit_id": "1CHN", "doi": "10.1006/jmbi.1994.1308", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CHN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MAGNESIUM BINDING TO THE BACTERIAL CHEMOTAXIS PROTEIN CHEY RESULTS IN LARGE CONFORMATIONAL CHANGES INVOLVING ITS FUNCTIONAL SURFACE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CHEMOTAXIS PROTEIN CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1D4Z", "evidence_id": "EV-PDB-1D4Z-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1D4Z", "doi": "10.1074/jbc.M909908199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1D4Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF CHEY-95IV, A HYPERACTIVE CHEY MUTANT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1E6K", "evidence_id": "EV-PDB-1E6K-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1E6K", "doi": "10.1006/jmbi.2000.4507", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1E6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Two-component signal transduction system D12A mutant of CheY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.3, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EHC", "evidence_id": "EV-PDB-1EHC-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26}, "provenance": {"deposit_id": "1EHC", "doi": "10.1074/jbc.272.18.11850", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EHC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CHEMOTAXIS CHEY PROTEIN (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1F4V", "evidence_id": "EV-PDB-1F4V-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.22}, "provenance": {"deposit_id": "1F4V", "doi": "10.1038/83053", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1F4V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF ACTIVATED CHEY BOUND TO THE N-TERMINUS OF FLIM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "CHEMOTAXIS PROTEIN CHEY (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FFG", "evidence_id": "EV-PDB-1FFG-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1FFG", "doi": "10.1107/S090744490001492X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FFG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY AT 2.1 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "CHEMOTAXIS PROTEIN CHEY (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FFS", "evidence_id": "EV-PDB-1FFS-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "1FFS", "doi": "10.1107/S090744490001492X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FFS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY FROM CRYSTALS SOAKED IN ACETYL PHOSPHATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN", "PON"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "CHEMOTAXIS PROTEIN CHEY (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FFW", "evidence_id": "EV-PDB-1FFW-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1FFW", "doi": "10.1107/S090744490001492X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FFW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY WITH A BOUND IMIDO DIPHOSPHATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CHEMOTAXIS CHEY PROTEIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FQW", "evidence_id": "EV-PDB-1FQW-1", "mappings": [{"confidence": "high", "justification": "Title: activated CheY; BeF3- (BEF) bound.", "rule": "curator_assignment", "state_id": "CheY-active", "who": "curator:draft (unreviewed)"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.37}, "provenance": {"deposit_id": "1FQW", "doi": "10.1074/jbc.M101002200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FQW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF ACTIVATED CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JBE", "evidence_id": "EV-PDB-1JBE-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.08}, "provenance": {"deposit_id": "1JBE", "doi": "10.1074/jbc.C100295200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JBE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.08 A Structure of apo-Chey reveals meta-active conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BCN", "BEF", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Chemotaxis protein cheY (chains Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KMI", "evidence_id": "EV-PDB-1KMI-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "1KMI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KMI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF AN E.COLI CHEMOTAXIS PROTEIN, CHEZ"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CHEY PROTEIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1UDR", "evidence_id": "EV-PDB-1UDR-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1UDR", "doi": "10.1006/jmbi.2000.4507", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1UDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CHEY MUTANT WITH LYS 91 REPLACED BY ASP, LYS 92 REPLACED BY ALA, ILE 96 REPLACED BY LYS AND ALA 98 REPLACED BY LEU (STABILIZING MUTATIONS IN HELIX 4)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CHEY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1VLZ", "evidence_id": "EV-PDB-1VLZ-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "1VLZ", "doi": "10.1074/jbc.270.29.17386", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1VLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "UNCOUPLED PHOSPHORYLATION AND ACTIVATION IN BACTERIAL CHEMOTAXIS: THE 2.1 ANGSTROM STRUCTURE OF A THREONINE TO ISOLEUCINE MUTANT AT POSITION 87 OF CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "CHEY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YMU", "evidence_id": "EV-PDB-1YMU-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1YMU", "doi": "10.1006/jmbi.1996.0151", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YMU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIGNAL TRANSDUCTION PROTEIN CHEY MUTANT WITH MET 17 REPLACED BY GLY (M17G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YMV", "evidence_id": "EV-PDB-1YMV-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1YMV", "doi": "10.1006/jmbi.1996.0151", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YMV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIGNAL TRANSDUCTION PROTEIN CHEY MUTANT WITH PHE 14 REPLACED BY GLY, SER 15 REPLACED BY GLY, AND MET 17 REPLACED BY GLY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2B1J", "evidence_id": "EV-PDB-2B1J-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "2B1J", "doi": "10.1128/JB.00637-06", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2B1J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Unphosphorylated CheY Bound to the N-Terminus of FliM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.84, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein cheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ID9", "evidence_id": "EV-PDB-2ID9-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "2ID9", "doi": "10.1016/j.abb.2008.08.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ID9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.85 A Structure of T87I/Y106W Phosphono-CheY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3F7N", "evidence_id": "EV-PDB-3F7N-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3F7N", "doi": "10.1016/j.jmb.2009.07.064", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3F7N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CheY triple mutant F14E, N59M, E89L complexed with BeF3- and Mn2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FFW", "evidence_id": "EV-PDB-3FFW-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3FFW", "doi": "10.1016/j.jmb.2009.07.064", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FFW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CheY triple mutant F14Q, N59K, E89Y complexed with BeF3- and Mn2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FFX", "evidence_id": "EV-PDB-3FFX-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.01}, "provenance": {"deposit_id": "3FFX", "doi": "10.1016/j.jmb.2009.07.064", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FFX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CheY triple mutant F14E, N59R, E89H complexed with BeF3- and Mn2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MYY", "evidence_id": "EV-PDB-3MYY-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3MYY", "doi": "10.1021/acs.biochem.1c00246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MYY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of E. Coli CheY mutant A113P bound to Beryllium fluoride"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "MG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OLV", "evidence_id": "EV-PDB-3OLV-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.697}, "provenance": {"deposit_id": "3OLV", "doi": "10.1021/acs.biochem.6b00645", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OLV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural and functional effects of substitution at position T+1 in CheY: CheYA88V-BeF3-Mg complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "CL", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OLW", "evidence_id": "EV-PDB-3OLW-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.304}, "provenance": {"deposit_id": "3OLW", "doi": "10.1021/acs.biochem.6b00645", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OLW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural and functional effects of substitution at position T+1 in CheY: CheYA88T-BeF3-Mn complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MG", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OLX", "evidence_id": "EV-PDB-3OLX-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3OLX", "doi": "10.1021/acs.biochem.6b00645", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OLX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural and functional effects of substitution at position T+1 in CheY: CheYA88S-BeF3-Mn complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MN", "NH4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.25, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OO0", "evidence_id": "EV-PDB-3OO0-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "3OO0", "doi": "10.1021/acs.biochem.1c00246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OO0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of apo CheY A113P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OO1", "evidence_id": "EV-PDB-3OO1-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3OO1", "doi": "10.1021/acs.biochem.1c00246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OO1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of E. Coli CheY mutant A113P in the absence of Sulfate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVK", "evidence_id": "EV-PDB-3RVK-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.16}, "provenance": {"deposit_id": "3RVK", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89Q"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.25, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVJ", "evidence_id": "EV-PDB-3RVJ-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3RVJ", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89Q"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OLY", "evidence_id": "EV-PDB-3OLY-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "3OLY", "doi": "10.1021/acs.biochem.6b00645", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OLY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural and functional effects of substitution at position T+1 in CheY: CheYA88M-BeF3-Mn complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "NH4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FGZ", "evidence_id": "EV-PDB-3FGZ-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3FGZ", "doi": "10.1016/j.jmb.2009.07.064", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FGZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CheY triple mutant F14E, N59M, E89R complexed with BeF3- and Mn2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3FFT", "evidence_id": "EV-PDB-3FFT-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.21}, "provenance": {"deposit_id": "3FFT", "doi": "10.1016/j.jmb.2009.07.064", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3FFT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CheY double mutant F14E, E89R complexed with BeF3- and Mn2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3CHY", "evidence_id": "EV-PDB-3CHY-1", "mappings": [{"confidence": "high", "justification": "Unphosphorylated CheY, 1.7 Å.", "rule": "curator_assignment", "state_id": "CheY-inactive", "who": "curator:draft (unreviewed)"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.66}, "provenance": {"deposit_id": "3CHY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3CHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF ESCHERICHIA COLI CHEY REFINED AT 1.7-ANGSTROM RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Chemotaxis protein CheY (chains Y)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LP4", "evidence_id": "EV-PDB-2LP4-2", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LP4", "doi": "10.1021/bi300147m", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LP4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of P1-CheY/P2 complex in bacterial chemotaxis"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.88, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein cheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2IDM", "evidence_id": "EV-PDB-2IDM-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2IDM", "doi": "10.1016/j.abb.2008.08.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2IDM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2.00 A Structure of T87I/Y106W Phosphono-CheY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein cheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ID7", "evidence_id": "EV-PDB-2ID7-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "2ID7", "doi": "10.1016/j.abb.2008.08.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ID7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.75 A Structure of T87I Phosphono-CheY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "MN", "XE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZDM", "evidence_id": "EV-PDB-1ZDM-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "1ZDM", "doi": "10.1110/ps.041231005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZDM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Activated CheY Bound to Xe"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein cheY (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1U8T", "evidence_id": "EV-PDB-1U8T-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1U8T", "doi": "10.1016/j.jmb.2004.07.084", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1U8T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of CheY D13K Y106W alone and in complex with a FliM peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein cheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MIH", "evidence_id": "EV-PDB-1MIH-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1MIH", "doi": "10.1128/JB.185.5.1495-1502.2003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MIH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A ROLE FOR CHEY GLU 89 IN CHEZ-MEDIATED DEPHOSPHORYLATION OF THE E. COLI CHEMOTAXIS RESPONSE REGULATOR CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HEY", "evidence_id": "EV-PDB-1HEY-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.24}, "provenance": {"deposit_id": "1HEY", "doi": "10.1006/jmbi.1995.0326", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HEY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "INVESTIGATING THE STRUCTURAL DETERMINANTS OF THE P21-LIKE TRIPHOSPHATE AND MG2+ BINDING SITE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "CHEY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EAY", "evidence_id": "EV-PDB-1EAY-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1EAY", "doi": "10.1073/pnas.95.13.7333", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EAY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CHEY-BINDING (P2) DOMAIN OF CHEA IN COMPLEX WITH CHEY FROM ESCHERICHIA COLI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "CHEMOTAXIS PROTEIN CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1E6M", "evidence_id": "EV-PDB-1E6M-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1E6M", "doi": "10.1006/jmbi.2000.4507", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1E6M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "TWO-COMPONENT SIGNAL TRANSDUCTION SYSTEM D57A MUTANT OF CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1E6L", "evidence_id": "EV-PDB-1E6L-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1E6L", "doi": "10.1006/jmbi.2000.4507", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1E6L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Two-component signal transduction system D13A mutant of CheY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "CHEMOTAXIS PROTEIN Y (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DJM", "evidence_id": "EV-PDB-1DJM-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1DJM", "doi": "10.1006/jmbi.2000.3595", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DJM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF BEF3-ACTIVATED CHEY FROM ESCHERICHIA COLI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CYE", "evidence_id": "EV-PDB-1CYE-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1CYE", "doi": "10.1016/S0022-2836(05)80150-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CYE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "THREE DIMENSIONAL STRUCTURE OF CHEMOTACTIC CHE Y PROTEIN IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE METHODS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BDJ", "evidence_id": "EV-PDB-1BDJ-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "1BDJ", "doi": "10.1107/S0907444999005053", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "CHEY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AB5", "evidence_id": "EV-PDB-1AB5-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "1AB5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF CHEY MUTANT F14N, V21T"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "CHEY (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1A0O", "evidence_id": "EV-PDB-1A0O-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "1A0O", "doi": "10.1038/nsb0198-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1A0O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.25, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVL", "evidence_id": "EV-PDB-3RVL-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "3RVL", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89R"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.25, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVM", "evidence_id": "EV-PDB-3RVM-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "3RVM", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D and E89R"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.25, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVN", "evidence_id": "EV-PDB-3RVN-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "3RVN", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89Y"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVO", "evidence_id": "EV-PDB-3RVO-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "3RVO", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89Y"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BEF", "GOL", "MG", "MN", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVP", "evidence_id": "EV-PDB-3RVP-1", "mappings": [{"confidence": "high", "justification": "BeF3- (BEF) bound: phosphoryl mimic that activates CheY.", "rule": "chey-bef3-active", "state_id": "CheY-active", "who": "rule:chey-bef3-active"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.404}, "provenance": {"deposit_id": "3RVP", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVQ", "evidence_id": "EV-PDB-3RVQ-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "3RVQ", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MN", "MOO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVR", "evidence_id": "EV-PDB-3RVR-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3RVR", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheYN59D/E89R Molybdate complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "CHEY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5CHY", "evidence_id": "EV-PDB-5CHY-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "5CHY", "doi": "10.1074/jbc.272.38.23758", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5CHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF CHEMOTAXIS PROTEIN CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "CHEY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6CHY", "evidence_id": "EV-PDB-6CHY-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33}, "provenance": {"deposit_id": "6CHY", "doi": "10.1074/jbc.272.38.23758", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6CHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF CHEMOTAXIS PROTEIN CHEY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6TG7", "evidence_id": "EV-PDB-6TG7-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "6TG7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6TG7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the CheY in presence of magnesium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MN", "SO4", "WO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chemotaxis protein CheY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RVS", "evidence_id": "EV-PDB-3RVS-1", "mappings": [{"confidence": "low", "justification": "Structure without a phosphoryl mimic; usually inactive, but mutants can be partly active.", "rule": "chey-unphosphorylated", "state_id": "CheY-inactive", "who": "rule:chey-unphosphorylated"}], "molecule_id": "P0AE67", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3RVS", "doi": "10.1021/acs.biochem.5b00286", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RVS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the CheYN59D/E89R Tungstate complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-sorbitol"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "MALTODEXTRIN-BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FQA", "evidence_id": "EV-PDB-1FQA-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1FQA", "doi": "10.1006/jmbi.2001.4456", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FQA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF MALTOTETRAITOL BOUND TO OPEN-FORM MALTODEXTRIN BINDING PROTEIN IN P2(1)CRYSTAL FORM"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JVX", "evidence_id": "EV-PDB-1JVX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1JVX", "doi": "10.1093/protein/15.11.895", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Maltodextrin-binding protein variant D207C/A301GS/P316C cross-linked in crystal"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JVY", "evidence_id": "EV-PDB-1JVY-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1JVY", "doi": "10.1093/protein/15.11.895", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JVY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Maltodextrin-binding protein variant D207C/A301GS/P316C with beta-mercaptoethanol mixed disulfides"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "MALTOSE-BINDING PROTEIN MUTANT MALE31 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LAX", "evidence_id": "EV-PDB-1LAX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1LAX", "doi": "10.1110/ps.0235103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LAX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF MALE31, A DEFECTIVE FOLDING MUTANT OF MALTOSE-BINDING PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["XE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1LLS", "evidence_id": "EV-PDB-1LLS-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1LLS", "doi": "10.1016/S0022-2836(02)00739-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1LLS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF UNLIGANDED MALTOSE BINDING PROTEIN WITH XENON"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MALTODEXTRIN BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MDQ", "evidence_id": "EV-PDB-1MDQ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1MDQ", "doi": "10.1006/jmbi.1994.0059", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MDQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "REFINED STRUCTURES OF TWO INSERTION(SLASH)DELETION MUTANTS PROBE FUNCTION OF THE MALTODEXTRIN BINDING PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PROTEIN (HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA) (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MG1", "evidence_id": "EV-PDB-1MG1-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1MG1", "doi": "10.1073/pnas.96.8.4319", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MG1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HTLV-1 GP21 ECTODOMAIN/MALTOSE-BINDING PROTEIN CHIMERA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MALTODEXTRIN-BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MPB", "evidence_id": "EV-PDB-1MPB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1MPB", "doi": "10.1006/jmbi.1996.0646", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MPB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MALTODEXTRIN-BINDING PROTEIN (MALTOSE-BINDING PROTEIN) MUTANT, WITH ARGININE REPLACING TRYPTOPHAN AT POSITION 230 (TRP-230-ARG)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MALTODEXTRIN-BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MPC", "evidence_id": "EV-PDB-1MPC-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1MPC", "doi": "10.1006/jmbi.1996.0646", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MPC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MALTODEXTRIN-BINDING PROTEIN (MALTOSE-BINDING PROTEIN) MUTANT, WITH ARGININE REPLACING TRYPTOPHAN AT POSITION 230 (TRP-230-ARG)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NL5", "evidence_id": "EV-PDB-1NL5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1NL5", "doi": "10.1074/jbc.M301004200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NL5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Engineered High-affinity Maltose-Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "maltose-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NMU", "evidence_id": "EV-PDB-1NMU-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.31}, "provenance": {"deposit_id": "1NMU", "doi": "10.1016/S0022-2836(02)01476-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NMU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-L30"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "D-MALTODEXTRIN BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OMP", "evidence_id": "EV-PDB-1OMP-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1OMP", "doi": "10.1021/bi00159a003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OMP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTALLOGRAPHIC EVIDENCE OF A LARGE LIGAND-INDUCED HINGE-TWIST MOTION BETWEEN THE TWO DOMAINS OF THE MALTODEXTRIN-BINDING PROTEIN INVOLVED IN ACTIVE TRANSPORT AND CHEMOTAXIS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chimera of Maltose-binding periplasmic protein and Argonaute 2 (chains A,P,Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1R6Z", "evidence_id": "EV-PDB-1R6Z-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1R6Z", "doi": "10.1038/nsb1016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1R6Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SVX", "evidence_id": "EV-PDB-1SVX-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.24}, "provenance": {"deposit_id": "1SVX", "doi": "10.1038/nbt962", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Maltose binding protein fused with designed helical protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Y4C", "evidence_id": "EV-PDB-1Y4C-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1Y4C", "doi": "10.1073/pnas.0408890102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Y4C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Designed Helical Protein fusion MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YTV", "evidence_id": "EV-PDB-1YTV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1YTV", "doi": "10.1107/S1744309105007293", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YTV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Maltose-binding protein fusion to a C-terminal fragment of the V1a vasopressin receptor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZIU", "evidence_id": "EV-PDB-1ZIU-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1ZIU", "doi": "10.1016/j.jmb.2005.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZIU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of nickel-bound engineered Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZJL", "evidence_id": "EV-PDB-1ZJL-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1ZJL", "doi": "10.1016/j.jmb.2005.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZJL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of zinc-bound engineered maltose binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZKB", "evidence_id": "EV-PDB-1ZKB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1ZKB", "doi": "10.1016/j.jmb.2005.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZKB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Zinc-free Engineered maltose binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZMG", "evidence_id": "EV-PDB-1ZMG-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1ZMG", "doi": "10.1016/j.jmb.2005.10.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZMG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of copper-bound engineered maltose binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1MC1", "branched: alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Monobody P' (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/21DH", "evidence_id": "EV-PDB-21DH-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "21DH", "doi": "10.1107/S2053230X26000798", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/21DH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused Monobody P' in complex with HPPU"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Leukocyte receptor cluster member 8 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/28WZ", "evidence_id": "EV-PDB-28WZ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "28WZ", "doi": "10.1038/s41586-026-10650-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/28WZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human LENG8-PCID2-SEM1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N44", "evidence_id": "EV-PDB-2N44-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N44", "doi": "10.1038/nmeth.3455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N44"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "EC-NMR Structure of Escherichia coli Maltose-binding protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data. Northeast Structural Genomics Consortium target ER690"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2MV0", "evidence_id": "EV-PDB-2MV0-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2MV0", "doi": "10.1073/pnas.1203013109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2MV0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KLF", "evidence_id": "EV-PDB-2KLF-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KLF", "doi": "10.1002/anie.200902561", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KLF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "PERE NMR structure of maltodextrin-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2H25", "evidence_id": "EV-PDB-2H25-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2H25", "doi": "10.1038/nmeth938", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2H25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution Structure of Maltose Binding Protein complexed with beta-cyclodextrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2D21", "evidence_id": "EV-PDB-2D21-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2D21", "doi": "10.1038/nature04525", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2D21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR Structure of stereo-array isotope labelled (SAIL) maltodextrin-binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Leukocyte receptor cluster member 8 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/28XA", "evidence_id": "EV-PDB-28XA-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.86}, "provenance": {"deposit_id": "28XA", "doi": "10.1038/s41586-026-10650-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/28XA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human UAP56 NTD - LENG8-PCID2-SEM1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,SAC3 domain-containing protein 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/28WY", "evidence_id": "EV-PDB-28WY-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "28WY", "doi": "10.1038/s41586-026-10650-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/28WY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human SAC3D1-PCID2-SEM1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1T0K", "evidence_id": "EV-PDB-1T0K-3", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "1T0K", "doi": "10.1016/j.str.2004.04.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1T0K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Joint X-ray and NMR Refinement of Yeast L30e-mRNA complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PEB", "evidence_id": "EV-PDB-1PEB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1PEB", "doi": "10.1074/jbc.M301004200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LIGAND-FREE HIGH-AFFINITY MALTOSE-BINDING PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1N3X", "evidence_id": "EV-PDB-1N3X-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1N3X", "doi": "10.1074/jbc.M301004200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1N3X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ligand-free High-Affinity Maltose-Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1N3W", "evidence_id": "EV-PDB-1N3W-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1N3W", "doi": "10.1074/jbc.M301004200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1N3W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Engineered High-Affinity Maltose-Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MALTODEXTRIN-BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MPD", "evidence_id": "EV-PDB-1MPD-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1MPD", "doi": "10.1006/jmbi.1996.0646", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MPD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MALTODEXTRIN-BINDING PROTEIN (MALTOSE-BINDING PROTEIN) MUTANT, WITH ARGININE REPLACING TRYPTOPHAN AT POSITION 230 (TRP-230-ARG), COMPLEXED WITH MALTOSE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltose binding-a1 homeodomain protein chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MH4", "evidence_id": "EV-PDB-1MH4-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1MH4", "doi": "10.1110/ps.0219103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MH4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "maltose binding-a1 homeodomain protein chimera, crystal form II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltose binding-a1 homeodomain protein chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MH3", "evidence_id": "EV-PDB-1MH3-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1MH3", "doi": "10.1110/ps.0219103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MH3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "maltose binding-a1 homeodomain protein chimera, crystal form I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "MALTODEXTRIN BINDING PROTEIN (chains 1,2)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1MDP", "evidence_id": "EV-PDB-1MDP-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1MDP", "doi": "10.1006/jmbi.1994.0059", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1MDP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "REFINED STRUCTURES OF TWO INSERTION(SLASH)DELETION MUTANTS PROBE FUNCTION OF THE MALTODEXTRIN BINDING PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JW5", "evidence_id": "EV-PDB-1JW5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1JW5", "doi": "10.1021/bi015784n", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JW5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Maltose Bound to Open-form Maltodextrin-binding Protein in P1 Crystal"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1JW4", "evidence_id": "EV-PDB-1JW4-1", "mappings": [{"confidence": "high", "justification": "Ligand-free open structure; representative for the open apo state.", "rule": "curator_assignment", "state_id": "MBP-open-apo", "who": "curator:draft (unreviewed)"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1JW4", "doi": "10.1021/bi015784n", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1JW4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of ligand-free maltodextrin-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "MALTODEXTRIN-BINDING PROTEIN MALE-B133 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1IUD", "evidence_id": "EV-PDB-1IUD-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "1IUD", "doi": "10.1002/(SICI)1097-0134(199701)27:1<1::AID-PROT2>3.0.CO;2-L", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1IUD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MALTODEXTRIN-BINDING PROTEIN INSERTION/DELETION MUTANT WITH AN INSERTED B-CELL EPITOPE FROM THE PRES2 REGION OF HEPATITIS B VIRUS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GLC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "FUSION PROTEIN CONSISTING OF STAPHYLOCOCCUS ACCESSORY REGULATOR PROTEIN R AND MALTOSE BINDING PROTEIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1HSJ", "evidence_id": "EV-PDB-1HSJ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1HSJ", "doi": "10.1073/pnas.121013398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1HSJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARR MBP FUSION STRUCTURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-sorbitol"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "MALTODEXTRIN-BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FQB", "evidence_id": "EV-PDB-1FQB-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1FQB", "doi": "10.1006/jmbi.2001.4456", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FQB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF MALTOTRIOTOL BOUND TO OPEN-FORM MALTODEXTRIN BINDING PROTEIN IN P2(1)CRYSTAL FORM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "MALTODEXTRIN BINDING PERIPLASMIC PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EZP", "evidence_id": "EV-PDB-1EZP-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1EZP", "doi": "10.1006/jmbi.2000.3842", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EZP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EZO", "evidence_id": "EV-PDB-1EZO-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1EZO", "doi": "10.1006/jmbi.2000.3842", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EZO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-D-glucose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EZ9", "evidence_id": "EV-PDB-1EZ9-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1EZ9", "doi": "10.1021/bi015784n", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EZ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF MALTOTETRAITOL BOUND TO OPEN-FORM MALTODEXTRIN BINDING PROTEIN IN P1 CRYSTAL FORM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: Cycloheptakis-(1-4)-(alpha-D-glucopyranose)"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "D-MALTODEXTRIN BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1DMB", "evidence_id": "EV-PDB-1DMB-1", "mappings": [{"confidence": "medium", "justification": "Beta-cyclodextrin binds without closing MBP (as in 1DMB).", "rule": "mbp-cyclodextrin-open", "state_id": "MBP-open-apo", "who": "rule:mbp-cyclodextrin-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1DMB", "doi": "10.1021/bi00091a004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1DMB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "REFINED 1.8 ANGSTROMS STRUCTURE REVEALS THE MECHANISM OF BINDING OF A CYCLIC SUGAR, BETA-CYCLODEXTRIN, TO THE MALTODEXTRIN BINDING PROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N45", "evidence_id": "EV-PDB-2N45-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N45", "doi": "10.1038/nmeth.3455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N45"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "EC-NMR Structure of Escherichia coli Maltose-binding protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data with a second set of RDC data simulated for an alternative alignment tensor. Northeast Structural Genomics Consortium target ER690"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose Binding periplasmic Protein and Monobody MBP-74 Fusion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2OBG", "evidence_id": "EV-PDB-2OBG-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "2OBG", "doi": "10.1073/pnas.0700149104", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2OBG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Monobody MBP-74/Maltose Binding Protein Fusion Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2R6G", "evidence_id": "EV-PDB-2R6G-2", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "2R6G", "doi": "10.1038/nature06264", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2R6G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The Crystal Structure of the E. coli Maltose Transporter"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Sugar ABC transporter substrate-binding protein,Mitochondrial antiviral-signaling protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2VGQ", "evidence_id": "EV-PDB-2VGQ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "2VGQ", "doi": "10.1186/1472-6807-8-11", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2VGQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human IPS-1 CARD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ZXT", "evidence_id": "EV-PDB-2ZXT-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "2ZXT", "doi": "10.1073/pnas.0901793106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ZXT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Tim40/MIA40, a disulfide relay system in mitochondria, solved as MBP fusion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,TnsA endonuclease N-terminal domain-containing protein,TnsB transposase (chains R,S,T,U,V,W,X,a,b,c,d)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/30GA", "evidence_id": "EV-PDB-30GA-10", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "30GA", "doi": "10.64898/2026.05.18.725949", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/30GA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the PseCascade-TniQ-TnsC-TnsAB holocomplex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,TnsA endonuclease N-terminal domain-containing protein,TnsB transposase (chains R,S,T,U,V,W,X)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/30GB", "evidence_id": "EV-PDB-30GB-9", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "30GB", "doi": "10.64898/2026.05.18.725949", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/30GB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the PseCascade-TniQ-TnsC complex bound to PseTnsB-hook motifs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3C4M", "evidence_id": "EV-PDB-3C4M-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "3C4M", "doi": "10.1073/pnas.0801027105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3C4M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding protein Monobody YS1 Fusion (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3CSG", "evidence_id": "EV-PDB-3CSG-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.798}, "provenance": {"deposit_id": "3CSG", "doi": "10.1016/j.jmb.2008.06.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3CSG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Monobody YS1(MBP-74)/Maltose Binding Protein Fusion Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, LINKER, Zona pellucida protein 3 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3D4C", "evidence_id": "EV-PDB-3D4C-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "3D4C", "doi": "10.1038/nature07599", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3D4C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ZP-N domain of mammalian sperm receptor ZP3 (crystal form I)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein fused with RACK1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3DM0", "evidence_id": "EV-PDB-3DM0-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "3DM0", "doi": "10.1110/ps.035121.108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3DM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Maltose Binding Protein fusion with RACK1 from A. thaliana"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, LINKER, Zona pellucida protein 3 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EF7", "evidence_id": "EV-PDB-3EF7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "3EF7", "doi": "10.1038/nature07599", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EF7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ZP-N domain of mammalian sperm receptor ZP3 (crystal form III)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "fusion protein of CRFR1 extracellular domain and MBP (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EHS", "evidence_id": "EV-PDB-3EHS-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "3EHS", "doi": "10.1074/jbc.M805749200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BTB", "CA", "PEG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.75, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FUSION PROTEIN OF CRFR1 EXTRACELLULAR DOMAIN AND MBP (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EHU", "evidence_id": "EV-PDB-3EHU-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "3EHU", "doi": "10.1074/jbc.M805749200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EHU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A3P", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Heparan sulfate 2-O-sulfotransferase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3F5F", "evidence_id": "EV-PDB-3F5F-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "3F5F", "doi": "10.1073/pnas.0806975105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3F5F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of heparan sulfate 2-O-sulfotransferase from gallus gallus as a maltose binding protein fusion."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3G7V", "evidence_id": "EV-PDB-3G7V-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "3G7V", "doi": "10.1002/pro.145", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3G7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3G7W", "evidence_id": "EV-PDB-3G7W-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "3G7W", "doi": "10.1002/pro.145", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3G7W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fusion protein of Maltose-binding periplasmic domain and human parathyroid hormone receptor extracellular domain (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3H3G", "evidence_id": "EV-PDB-3H3G-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "3H3G", "doi": "10.1074/jbc.M109.022905", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3H3G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the extracellular domain of the human parathyroid hormone receptor (PTH1R) in complex with parathyroid hormone-related protein (PTHrP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "ZN", "branched: beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -160.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HPI", "evidence_id": "EV-PDB-3HPI-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3HPI", "doi": "10.1074/jbc.M109.089078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HPI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of maltose-binding protein mutant with bound sucrose"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "TAR", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -160.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HST", "evidence_id": "EV-PDB-3HST-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "3HST", "doi": "10.1128/JB.01615-09", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HST"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "N-Terminal RNASE H domain of rv2228c from mycobacterium tuberculosis as a fusion protein with maltose binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein, HUNTINGTIN FUSION PROTEIN (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IO6", "evidence_id": "EV-PDB-3IO6-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "3IO6", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IO6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C92-a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOU", "evidence_id": "EV-PDB-3IOU-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "3IOU", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C94"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOV", "evidence_id": "EV-PDB-3IOV-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "3IOV", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C99"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOW", "evidence_id": "EV-PDB-3IOW-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "3IOW", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C99-Hg"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3J9P", "evidence_id": "EV-PDB-3J9P-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.24}, "provenance": {"deposit_id": "3J9P", "doi": "10.1038/nature14367", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3J9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the TRPA1 ion channel determined by electron cryo-microscopy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -160.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KJT", "evidence_id": "EV-PDB-3KJT-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "3KJT", "doi": "10.1074/jbc.M109.089078", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KJT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Stimulation of the maltose transporter by a mutant sucrose binding protein gives insights into ABC transporter coupling"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Renin receptor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LBS", "evidence_id": "EV-PDB-3LBS-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "3LBS", "doi": "10.1016/j.bbrc.2011.03.074", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LBS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-bound form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MG", "PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Renin receptor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LC8", "evidence_id": "EV-PDB-3LC8-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3LC8", "doi": "10.1016/j.bbrc.2011.03.074", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LC8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-free form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MP6", "evidence_id": "EV-PDB-3MP6-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "3MP6", "doi": "10.1038/emboj.2011.193", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MP6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex Structure of Sgf29 and dimethylated H3K4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["4BZ", "ACY", "GOL", "NA", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MP8", "evidence_id": "EV-PDB-3MP8-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.92}, "provenance": {"deposit_id": "3MP8", "doi": "10.1038/emboj.2011.193", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Sgf29 tudor domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Bone marrow stromal antigen 2 fused to Maltose-binding periplasmic protein (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MQ9", "evidence_id": "EV-PDB-3MQ9-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "3MQ9", "doi": "10.1073/pnas.1011485107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MQ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317 Fused to MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose binding protein-CRFR2 alpha (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3N93", "evidence_id": "EV-PDB-3N93-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "3N93", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3N93"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fusion protein of Maltose-binding periplasmic protein and pituitary adenylate cyclase 1 Receptor-short (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3N94", "evidence_id": "EV-PDB-3N94-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3N94", "doi": "10.1371/journal.pone.0019682", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3N94"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose binding protein-CRFR2 alpha extracellular domain (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3N95", "evidence_id": "EV-PDB-3N95-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "3N95", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3N95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose binding protein-CRFR2 alpha (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3N96", "evidence_id": "EV-PDB-3N96-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "3N96", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3N96"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Advanced glycosylation end product-specific receptor (chains N)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3O3U", "evidence_id": "EV-PDB-3O3U-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.497}, "provenance": {"deposit_id": "3O3U", "doi": "10.1074/jbc.M110.169276", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3O3U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 11.1, "salt_mM": null, "temperature_c": -100.15}, "construct": {"description": "Maltose-binding periplasmic protein, Myelin protein P0 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OAI", "evidence_id": "EV-PDB-3OAI-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3OAI", "doi": "10.1002/prot.23164", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OAI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the extra-cellular domain of human myelin protein zero"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose ABC transporter periplasmic protein,Arah 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OB4", "evidence_id": "EV-PDB-3OB4-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.706}, "provenance": {"deposit_id": "3OB4", "doi": "10.1111/j.1398-9995.2010.02532.x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-fusion protein of the major peanut allergen Ara h 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MP1", "evidence_id": "EV-PDB-3MP1-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "3MP1", "doi": "10.1038/emboj.2011.193", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MP1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex structure of Sgf29 and trimethylated H3K4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "MALTODEXTRIN-BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3MBP", "evidence_id": "EV-PDB-3MBP-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "3MBP", "doi": "10.1016/S0969-2126(97)00253-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3MBP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MALTODEXTRIN-BINDING PROTEIN WITH BOUND MALTOTRIOSE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3L2J", "evidence_id": "EV-PDB-3L2J-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "3L2J", "doi": "10.1074/jbc.M109.093138", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3L2J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (PTH1R)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOT", "evidence_id": "EV-PDB-3IOT-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "3IOT", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C92-b"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding protein, huntingtin fusion protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOR", "evidence_id": "EV-PDB-3IOR-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "3IOR", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C95"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein fused with Allergen DERP7 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3H4Z", "evidence_id": "EV-PDB-3H4Z-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "3H4Z", "doi": "10.1016/j.jaci.2009.12.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3H4Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an MBP-Der p 7 fusion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.25, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FUSION PROTEIN OF CRFR1 EXTRACELLULAR DOMAIN AND MBP (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3EHT", "evidence_id": "EV-PDB-3EHT-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "3EHT", "doi": "10.1074/jbc.M805749200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3EHT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, LINKER, Zona pellucida protein 3 (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3D4G", "evidence_id": "EV-PDB-3D4G-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3D4G", "doi": "10.1038/nature07599", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3D4G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ZP-N domain of mammalian sperm receptor ZP3 (crystal form II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "EDO", "MN", "PEG", "PG4", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding protein Monobody YSX1 Fusion (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3CSB", "evidence_id": "EV-PDB-3CSB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.999}, "provenance": {"deposit_id": "3CSB", "doi": "10.1016/j.jmb.2008.06.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3CSB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Monobody YSX1/Maltose Binding Protein Fusion Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3A3C", "evidence_id": "EV-PDB-3A3C-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "3A3C", "doi": "10.1073/pnas.0901793106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3A3C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of TIM40/MIA40 fusing MBP, C296S and C298S mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MXT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2V93", "evidence_id": "EV-PDB-2V93-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2V93", "doi": "10.1038/NATURE06232", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2V93"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "EQUILLIBRIUM MIXTURE OF OPEN AND PARTIALLY-CLOSED SPECIES IN THE APO STATE OF MALTODEXTRIN-BINDING PROTEIN BY PARAMAGNETIC RELAXATION ENHANCEMENT NMR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NVU", "evidence_id": "EV-PDB-2NVU-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "2NVU", "doi": "10.1038/nature05490", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NVU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OSQ", "evidence_id": "EV-PDB-3OSQ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3OSQ", "doi": "10.1002/prot.23118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OSQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 175"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Green fluorescent protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OSR", "evidence_id": "EV-PDB-3OSR-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3OSR", "doi": "10.1002/prot.23118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OSR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Maltose-bound maltose sensor engineered by insertion of circularly permuted green fluorescent protein into E. coli maltose binding protein at position 311"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "IMD", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PGF", "evidence_id": "EV-PDB-3PGF-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3PGF", "doi": "10.1038/nsmb.2002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PGF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "MG", "PGV", "UMQ", "VO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PUV", "evidence_id": "EV-PDB-3PUV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "3PUV", "doi": "10.1073/pnas.1108858108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PUV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-VO4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ALF", "MG", "PGV", "UMQ", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PUW", "evidence_id": "EV-PDB-3PUW-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3PUW", "doi": "10.1073/pnas.1108858108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PUW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-AlF4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "MG", "PGV", "UMQ", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PUX", "evidence_id": "EV-PDB-3PUX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3PUX", "doi": "10.1073/pnas.1108858108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PUX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to ADP-BeF3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "MG", "PGV", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose transporter subunit; periplasmic-binding component of ABC superfamily (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PUY", "evidence_id": "EV-PDB-3PUY-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "3PUY", "doi": "10.1126/science.1200767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PUY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to AMP-PNP after crystal soaking of the pretranslocation state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "MG", "PGV", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose transporter subunit; periplasmic-binding component of ABC superfamily (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PUZ", "evidence_id": "EV-PDB-3PUZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "3PUZ", "doi": "10.1126/science.1200767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of a pre-translocation state MBP-Maltose transporter complex bound to AMP-PNP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltose-binding periplasmic protein,paxillin LD1,protein E6 chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PY7", "evidence_id": "EV-PDB-3PY7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.288}, "provenance": {"deposit_id": "3PY7", "doi": "10.1126/science.1229934", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PY7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of full-length Bovine Papillomavirus oncoprotein E6 in complex with LD1 motif of paxillin at 2.3A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q25", "evidence_id": "EV-PDB-3Q25-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3Q25", "doi": "10.1002/pro.630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q26", "evidence_id": "EV-PDB-3Q26-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.54}, "provenance": {"deposit_id": "3Q26", "doi": "10.1002/pro.630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q26"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyrstal structure of human alpha-synuclein (10-42) fused to maltose binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q27", "evidence_id": "EV-PDB-3Q27-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.302}, "provenance": {"deposit_id": "3Q27", "doi": "10.1002/pro.630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q27"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q28", "evidence_id": "EV-PDB-3Q28-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3Q28", "doi": "10.1002/pro.630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q28"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyrstal structure of human alpha-synuclein (58-79) fused to maltose binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "MG", "PGV", "UMQ", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RLF", "evidence_id": "EV-PDB-3RLF-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "3RLF", "doi": "10.1073/pnas.1108858108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RLF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to MgAMPPNP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IPA", "MAN", "RST", "SO4", "branched: alpha-D-arabinofuranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-L-rhamnopyranose-(1-6)]beta-D-glucopyranose", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RUM", "evidence_id": "EV-PDB-3RUM-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.851}, "provenance": {"deposit_id": "3RUM", "doi": "10.1021/ja208755j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RUM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "New strategy to analyze structures of glycopeptide antibiotic-target complexes"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SEV", "evidence_id": "EV-PDB-3SEV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "3SEV", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SEV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IOD", "NI", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SEX", "evidence_id": "EV-PDB-3SEX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "3SEX", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SEX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "GOL", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SEY", "evidence_id": "EV-PDB-3SEY-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "3SEY", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SEY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CAC", "GCS", "MAN", "NAG", "T55", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Maltose-binding periplasmic protein, C-terminal fused by Cys-Lys-D-Ala-D-Ala (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3VFJ", "evidence_id": "EV-PDB-3VFJ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "3VFJ", "doi": "10.1107/S0907444912050469", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3VFJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of monodechloro-teicoplanin in complex with its ligand, using MBP as a ligand carrier"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "3-ketoacyl-CoA thiolase, peroxisomal, Maltose-binding periplasmic protein (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3W15", "evidence_id": "EV-PDB-3W15-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "3W15", "doi": "10.1038/nsmb.2618", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3W15"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of peroxisomal targeting signal 2 (PTS2) of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase in complex with Pex7p and Pex21p"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Transmembrane oligosaccharyl transferase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WAI", "evidence_id": "EV-PDB-3WAI-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.897}, "provenance": {"deposit_id": "3WAI", "doi": "10.1186/1472-6807-13-11", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WAI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (AfAglB-L, O29867_ARCFU) from Archaeoglobus fulgidus as a MBP fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MES", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN, TRIPARTITE MOTIF-CONTAINING PROTEIN 5 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4B3N", "evidence_id": "EV-PDB-4B3N-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "4B3N", "doi": "10.1073/PNAS.1210903109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4B3N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of rhesus TRIM5alpha PRY/SPRY domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BL8", "evidence_id": "EV-PDB-4BL8-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "4BL8", "doi": "10.1107/S0907444913028473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BL8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of full-length human Suppressor of fused (SUFU)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BL9", "evidence_id": "EV-PDB-4BL9-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "4BL9", "doi": "10.1107/S0907444913028473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BL9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form I)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BLA", "evidence_id": "EV-PDB-4BLA-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "4BLA", "doi": "10.1107/S0907444913028473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BLA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BLB", "evidence_id": "EV-PDB-4BLB-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "4BLB", "doi": "10.1107/S0907444913028473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BLB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a human Suppressor of fused (SUFU)-GLI1p complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Beta-lactamase TEM chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DXB", "evidence_id": "EV-PDB-4DXB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.29}, "provenance": {"deposit_id": "4DXB", "doi": "10.1371/journal.pone.0039168", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DXB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "2.29A structure of the engineered MBP TEM-1 fusion protein RG13 in complex with zinc, P1 space group"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Beta-lactamase TEM chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DXC", "evidence_id": "EV-PDB-4DXC-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "4DXC", "doi": "10.1371/journal.pone.0039168", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the engineered MBP TEM-1 fusion protein RG13, C2 space group"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Myosin-binding protein C, cardiac-type chimeric protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EDQ", "evidence_id": "EV-PDB-4EDQ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.641}, "provenance": {"deposit_id": "4EDQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EDQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-fusion protein of myosin-binding protein c residues 149-269"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.1, "salt_mM": null, "temperature_c": -188.15}, "construct": {"description": "Maltose-binding periplasmic protein, Homeobox protein SIX1 chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EGC", "evidence_id": "EV-PDB-4EGC-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.994}, "provenance": {"deposit_id": "4EGC", "doi": "10.1038/nsmb.2505", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EGC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of MBP-fused Human Six1 Bound to Human Eya2 Eya Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PGE", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, uncharacterized protein chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EXK", "evidence_id": "EV-PDB-4EXK-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.28}, "provenance": {"deposit_id": "4EXK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EXK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A chimera protein containing MBP fused to the C-terminal domain of the uncharacterized protein STM14_2015 from Salmonella enterica"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4FE8", "evidence_id": "EV-PDB-4FE8-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "4FE8", "doi": "10.4161/pri.23807", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4FE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Htt36Q3H-EX1-X1-C1(Alpha)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4FEC", "evidence_id": "EV-PDB-4FEC-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "4FEC", "doi": "10.4161/pri.23807", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4FEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Htt36Q3H"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, UBIQUITIN LIGASE EA6P: chimeric protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GIZ", "evidence_id": "EV-PDB-4GIZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "4GIZ", "doi": "10.1126/science.1229934", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GIZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of full-length human papillomavirus oncoprotein E6 in complex with LXXLL peptide of ubiquitin ligase E6AP at 2.55 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Maltose-binding periplasmic protein, Survival motor neuron protein chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GLI", "evidence_id": "EV-PDB-4GLI-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.903}, "provenance": {"deposit_id": "4GLI", "doi": "10.1016/j.str.2012.08.024", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GLI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human SMN YG-Dimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MLI", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IFP", "evidence_id": "EV-PDB-4IFP-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9948}, "provenance": {"deposit_id": "4IFP", "doi": "10.1002/prot.24287", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IFP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray Crystal Structure of Human NLRP1 CARD Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "EDO", "MLI", "NA", "PEG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein, Novel protein similar to vertebrate guanylate binding protein family (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IRL", "evidence_id": "EV-PDB-4IRL-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.47}, "provenance": {"deposit_id": "4IRL", "doi": "10.1107/S1744309113015558", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IRL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": -80.0}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN FUSED WITH XENOPUS LAEVIS MCM10 COILED-COIL REGION (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4JBZ", "evidence_id": "EV-PDB-4JBZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "4JBZ", "doi": "10.1371/journal.pone.0070518", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4JBZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Mcm10 coiled-coil region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "IOD", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein, Caspase recruitment domain-containing protein 8 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IKM", "evidence_id": "EV-PDB-4IKM-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4606}, "provenance": {"deposit_id": "4IKM", "doi": "10.1107/S1744309113010075", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IKM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of CARD8 CARD domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "EDO", "MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose binding protein-CaKar3 motor domain fusion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4H1G", "evidence_id": "EV-PDB-4H1G-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "4H1G", "doi": "10.1016/j.bbrc.2012.10.101", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4H1G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Candida albicans Kar3 motor domain fused to maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4FED", "evidence_id": "EV-PDB-4FED-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.807}, "provenance": {"deposit_id": "4FED", "doi": "10.4161/pri.23807", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4FED"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Htt36Q3H"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BLD", "evidence_id": "EV-PDB-4BLD-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.802}, "provenance": {"deposit_id": "4BLD", "doi": "10.1107/S0907444913028473", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BLD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a human Suppressor of fused (SUFU)-GLI3p complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Repressor protein CI, Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WOA", "evidence_id": "EV-PDB-3WOA-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3WOA", "doi": "10.1002/2211-5463.12480", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WOA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of lambda repressor (1-45) fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SEW", "evidence_id": "EV-PDB-3SEW-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "3SEW", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SEW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "GOL", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SEU", "evidence_id": "EV-PDB-3SEU-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "3SEU", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SEU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form III)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SET", "evidence_id": "EV-PDB-3SET-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3SET", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SET"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "CU", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SES", "evidence_id": "EV-PDB-3SES-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3SES", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cu-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SER", "evidence_id": "EV-PDB-3SER-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "3SER", "doi": "10.1002/pro.727", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SER"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Zn-mediated Polymer of Maltose-binding Protein K26H/K30H by Synthetic Symmetrization"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q29", "evidence_id": "EV-PDB-3Q29-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3Q29", "doi": "10.1002/pro.630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q29"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyrstal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PGV", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose transporter subunit; periplasmic-binding component of ABC superfamily (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PV0", "evidence_id": "EV-PDB-3PV0-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "3PV0", "doi": "10.1126/science.1200767", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PV0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of a pre-translocation state MBP-Maltose transporter complex without nucleotide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BOG", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KEG", "evidence_id": "EV-PDB-4KEG-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "4KEG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KEG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of MBP Fused Human SPLUNC1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "FMT", "MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP-MCL1 chimera protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WMS", "evidence_id": "EV-PDB-4WMS-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "4WMS", "doi": "10.1371/journal.pone.0125010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WMS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF APO MBP-MCL1 AT 1.9A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["865", "EDO", "FMT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP-MCL1 chimera protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WMT", "evidence_id": "EV-PDB-4WMT-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "4WMT", "doi": "10.1371/journal.pone.0125010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WMT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF MBP-MCL1 BOUND TO ligand 1 AT 2.35A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "PEG", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, ubiquitin ligase E6AP (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XR8", "evidence_id": "EV-PDB-4XR8-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "4XR8", "doi": "10.1038/nature16481", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XR8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the HPV16 E6/E6AP/p53 ternary complex at 2.25 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose binding protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5BK1", "evidence_id": "EV-PDB-5BK1-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "5BK1", "doi": "10.1074/jbc.RA117.000656", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5BK1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EPE", "GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5BJZ", "evidence_id": "EV-PDB-5BJZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "5BJZ", "doi": "10.1074/jbc.RA117.000656", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5BJZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3Z", "evidence_id": "EV-PDB-5B3Z-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5B3Z", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-39) fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3Y", "evidence_id": "EV-PDB-5B3Y-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.901}, "provenance": {"deposit_id": "5B3Y", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-23) fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3X", "evidence_id": "EV-PDB-5B3X-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "5B3X", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in P41212 form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3W", "evidence_id": "EV-PDB-5B3W-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "5B3W", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in C2221 form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Oligosaccharyl transferase stt3 subunit related protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AZA", "evidence_id": "EV-PDB-5AZA-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.08}, "provenance": {"deposit_id": "5AZA", "doi": "10.1002/pro.2867", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AZA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-sAglB fusion protein with a 20-residue spacer in the connector helix"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Mitochondrial import receptor subunit TOM20 homolog (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AZ9", "evidence_id": "EV-PDB-5AZ9-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82}, "provenance": {"deposit_id": "5AZ9", "doi": "10.1002/pro.2867", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AZ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of (5-residue deleted)MBP-Tom20 fusion protein tethered with ALDH presequence via a disulfide bond"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AAC", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Mitochondrial import receptor subunit TOM20 homolog (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AZ8", "evidence_id": "EV-PDB-5AZ8-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "5AZ8", "doi": "10.1002/pro.2867", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AZ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-Tom20 fusion protein tethered with ALDH presequence via a disulfide bond"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Mitochondrial import receptor subunit TOM20 homolog (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AZ7", "evidence_id": "EV-PDB-5AZ7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "5AZ7", "doi": "10.1002/pro.2867", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AZ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-Tom20 fusion protein with a 4-residue spacer in the connector helix"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Mitochondrial import receptor subunit TOM20 homolog (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AZ6", "evidence_id": "EV-PDB-5AZ6-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "5AZ6", "doi": "10.1002/pro.2867", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AZ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-Tom20 fusion protein with a 2-residue spacer in the connector helix"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AQ9", "evidence_id": "EV-PDB-5AQ9-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "5AQ9", "doi": "10.1016/J.JMB.2016.03.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AQ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,TP53-regulated inhibitor of apoptosis 1 (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XZV", "evidence_id": "EV-PDB-4XZV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.58}, "provenance": {"deposit_id": "4XZV", "doi": "10.15252/embr.201540229", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XZV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SLMO1-TRIAP1 Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,TP53-regulated inhibitor of apoptosis 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XZS", "evidence_id": "EV-PDB-4XZS-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.12}, "provenance": {"deposit_id": "4XZS", "doi": "10.15252/embr.201540229", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XZS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of TRIAP1-MBP fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,MBP-PilA: c (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XA2", "evidence_id": "EV-PDB-4XA2-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.98}, "provenance": {"deposit_id": "4XA2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XA2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Major Type IV pilin of Acinetobacter baumannii"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Ataxin-3 chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WTH", "evidence_id": "EV-PDB-4WTH-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "4WTH", "doi": "10.1002/2211-5463.12029", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WTH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ataxin-3 Carboxy Terminal Region - Crystal C2 (triclinic)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3R7", "FMT", "MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP-MCL1 chimera protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WMX", "evidence_id": "EV-PDB-4WMX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4WMX", "doi": "10.1371/journal.pone.0125010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WMX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of MBP-MCL1 bound to ligand 6 at 2.0A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3R6", "EDO", "FMT", "MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP-MCL1 chimera protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WMW", "evidence_id": "EV-PDB-4WMW-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "4WMW", "doi": "10.1371/journal.pone.0125010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WMW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of MBP-MCL1 bound to ligand 5 at 1.9A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3R4", "CL", "MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBL-MCL1 chimera protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WMV", "evidence_id": "EV-PDB-4WMV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "4WMV", "doi": "10.1371/journal.pone.0125010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WMV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF MBP-MCL1 BOUND TO ligand 4 AT 2.4A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["19H", "EDO", "FMT", "MG", "NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP-MCL1 chimera protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WMU", "evidence_id": "EV-PDB-4WMU-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "4WMU", "doi": "10.1371/journal.pone.0125010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WMU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF MBP-MCL1 BOUND TO ligand 2 AT 1.55A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4WJV", "evidence_id": "EV-PDB-4WJV-2", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "4WJV", "doi": "10.1083/jcb.201408111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4WJV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Rsa4 in complex with the Nsa2 binding peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TMO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -174.05}, "construct": {"description": "maltose-binding protein, pilin chimera (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4TSM", "evidence_id": "EV-PDB-4TSM-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.899}, "provenance": {"deposit_id": "4TSM", "doi": "10.1016/j.str.2014.11.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4TSM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-fusion protein of PilA1 from C. difficile R20291 residues 26-166"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "Maltose-binding periplasmic protein, Receptor activity-modifying protein 1, Calcitonin gene-related peptide type 1 receptor fusion protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4RWG", "evidence_id": "EV-PDB-4RWG-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.44}, "provenance": {"deposit_id": "4RWG", "doi": "10.1016/j.molcel.2015.04.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4RWG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the CLR:RAMP1 extracellular domain heterodimer with bound high affinity CGRP analog"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.3, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "Maltose transporter subunit, Receptor activity-modifying protein 2, Calcitonin gene-related peptide type 1 receptor fusion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4RWF", "evidence_id": "EV-PDB-4RWF-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.76}, "provenance": {"deposit_id": "4RWF", "doi": "10.1016/j.molcel.2015.04.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4RWF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MLI", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Maltose-binding periplasmic protein, Survival Motor Neuron protein chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4RG5", "evidence_id": "EV-PDB-4RG5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4RG5", "doi": "10.1074/jbc.M115.667279", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4RG5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of S. Pombe SMN YG-Dimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Disks large-associated protein 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4R0Y", "evidence_id": "EV-PDB-4R0Y-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4R0Y", "doi": "10.1016/j.bbrc.2014.08.073", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4R0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Maltose-binding Protein Fusion with the C-terminal GH1 domain of Guanylate Kinase-associated Protein from Rattus norvegicus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["COA", "FLC", "GOL", "MG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Maltose-binding periplasmic protein, 4'-phosphopantetheinyl transferase chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4QVH", "evidence_id": "EV-PDB-4QVH-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "4QVH", "doi": "10.1016/j.jsb.2014.10.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4QVH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FLC", "GLC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, JmjC domain-containing protein 7 chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4QSZ", "evidence_id": "EV-PDB-4QSZ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "4QSZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4QSZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of mouse JMJd7 fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose ABC transporter periplasmic protein, Truncated replication protein RepA (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PQK", "evidence_id": "EV-PDB-4PQK-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.401}, "provenance": {"deposit_id": "4PQK", "doi": "10.1073/pnas.1406065111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PQK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "C-Terminal domain of DNA binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MLI", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose ABC transporter periplasmic protein,Prepilin-type N-terminal cleavage/methylation domain protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4PE2", "evidence_id": "EV-PDB-4PE2-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.724}, "provenance": {"deposit_id": "4PE2", "doi": "10.1016/j.str.2014.11.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4PE2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP PilA1 CD160"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Chimera of Maltose-binding periplasmic protein and Kinesin family member 14 protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OZQ", "evidence_id": "EV-PDB-4OZQ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "4OZQ", "doi": "10.1016/j.jmb.2014.05.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OZQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the mouse Kif14 motor domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Maltose ABC transporter periplasmic protein, pilin protein chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4OGM", "evidence_id": "EV-PDB-4OGM-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.234}, "provenance": {"deposit_id": "4OGM", "doi": "10.1016/j.str.2014.11.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4OGM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-fusion protein of PilA1 residues 26-159"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Extracellular solute-binding protein family 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4O4B", "evidence_id": "EV-PDB-4O4B-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "4O4B", "doi": "10.1038/ncomms5178", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4O4B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of an Inositol hexakisphosphate kinase EhIP6KA as a fusion protein with maltose binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Maltose-binding periplasmic protein, ATP-dependent Clp protease adaptor protein ClpS containing protein chimeric construct (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4O2X", "evidence_id": "EV-PDB-4O2X-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "4O2X", "doi": "10.1002/pro.2868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4O2X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a malarial protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NUF", "evidence_id": "EV-PDB-4NUF-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "4NUF", "doi": "10.1073/pnas.1322827111", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NUF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SHP/EID1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A3P", "NPO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose", "branched: beta-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Heparan sulfate 2-O-sulfotransferase 1 fusion (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NDZ", "evidence_id": "EV-PDB-4NDZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "4NDZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NDZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Maltose Binding Protein fusion to 2-O-Sulfotransferase with bound heptasaccharide and PAP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4N4X", "evidence_id": "EV-PDB-4N4X-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.501}, "provenance": {"deposit_id": "4N4X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4N4X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the MBP fused human SPLUNC1 (native form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "MALTODEXTRIN BINDING PROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MBP", "evidence_id": "EV-PDB-4MBP-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4MBP", "doi": "10.1016/S0969-2126(97)00253-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MBP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MALTODEXTRIN BINDING PROTEIN WITH BOUND MALTETROSE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose ABC transporter periplasmic protein and NR2E3 protein chimeric construct (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LOG", "evidence_id": "EV-PDB-4LOG-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "4LOG", "doi": "10.1371/journal.pone.0074359", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LOG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of the orphan nuclear receptor PNR ligand binding domain fused with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Phosphoprotein, chimeric construct (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KYE", "evidence_id": "EV-PDB-4KYE-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "4KYE", "doi": "10.1002/pro.2336", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KYE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Partial Structure of the C-terminal domain of the HPIV4B phosphoprotein, fused to MBP."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.3, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Maltose-binding periplasmic protein, Phosphoprotein, chimeric construct (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KYD", "evidence_id": "EV-PDB-4KYD-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.21}, "provenance": {"deposit_id": "4KYD", "doi": "10.1002/pro.2336", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KYD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Partial Structure of the C-terminal domain of the HPIV4B phosphoprotein, fused to MBP."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BO3", "EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Phosphoprotein,  chimeric construct (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KYC", "evidence_id": "EV-PDB-4KYC-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "4KYC", "doi": "10.1002/pro.2336", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KYC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the C-terminal domain of the Menangle virus phosphoprotein, fused to MBP."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Chimera fusion protein of ESX-1 secretion system protein eccD1 and Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KV3", "evidence_id": "EV-PDB-4KV3-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "4KV3", "doi": "10.1186/s12900-016-0056-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KV3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ubiquitin-like domain of the Mycobacterium tuberculosis type VII secretion system protein EccD1 as maltose-binding protein fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "MG", "PGV", "UMQ", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KI0", "evidence_id": "EV-PDB-4KI0-2", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.38}, "provenance": {"deposit_id": "4KI0", "doi": "10.1073/pnas.1311407110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KI0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to maltohexaose"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PGV", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KHZ", "evidence_id": "EV-PDB-4KHZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "4KHZ", "doi": "10.1073/pnas.1311407110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the maltose-binding protein/maltose transporter complex in an pre-translocation conformation bound to maltoheptaose"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4JKM", "evidence_id": "EV-PDB-4JKM-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.263}, "provenance": {"deposit_id": "4JKM", "doi": "10.1016/j.chembiol.2015.08.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4JKM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Clostridium perfringens beta-glucuronidase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "PO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5BK2", "evidence_id": "EV-PDB-5BK2-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5BK2", "doi": "10.1074/jbc.RA117.000656", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5BK2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of maltose binding protein in complex with a peristeric synthetic antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MG", "MPD", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Maltose-binding periplasmic protein,PilA fusion protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5CFV", "evidence_id": "EV-PDB-5CFV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "5CFV", "doi": "10.1074/jbc.M116.751099", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5CFV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fusion of Maltose-binding Protein and PilA from Acinetobacter nosocomialis M2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Telomerase-associated protein 19 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DFM", "evidence_id": "EV-PDB-5DFM-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.301}, "provenance": {"deposit_id": "5DFM", "doi": "10.1126/science.aab4070", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DFM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Tetrahymena telomerase p19 fused to MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GTP", "MG", "PRO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Nuclear pore complex protein Nup214 (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DIS", "evidence_id": "EV-PDB-5DIS-4", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "5DIS", "doi": "10.1016/j.celrep.2015.09.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DIS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "TSN", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein, Histone deacetylase 6 chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5EDU", "evidence_id": "EV-PDB-5EDU-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "5EDU", "doi": "10.1038/nchembio.2134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5EDU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5FIO", "evidence_id": "EV-PDB-5FIO-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "5FIO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5FIO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DARPins as a new tool for experimental phasing in protein crystallography"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GRU", "evidence_id": "EV-PDB-5GRU-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.955}, "provenance": {"deposit_id": "5GRU", "doi": "10.1038/srep34515", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GRU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of mono-specific diabody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.2, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GS2", "evidence_id": "EV-PDB-5GS2-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.592}, "provenance": {"deposit_id": "5GS2", "doi": "10.1038/srep34515", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GS2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of diabody complex with repebody and MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,PigG (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GXV", "evidence_id": "EV-PDB-5GXV-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "5GXV", "doi": "10.1016/j.ijbiomac.2017.02.088", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GXV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of PigG"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MNDA PYD domain with MBP tag (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5H7Q", "evidence_id": "EV-PDB-5H7Q-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.451}, "provenance": {"deposit_id": "5H7Q", "doi": "10.1038/srep40991", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5H7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human MNDA PYD domain with MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BGC", "EDO", "NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ComP (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HZ7", "evidence_id": "EV-PDB-5HZ7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.43}, "provenance": {"deposit_id": "5HZ7", "doi": "10.1016/j.str.2016.04.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HZ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High-resolution crystal structure of the minor DNA-binding pilin ComP from Neisseria meningitidis in fusion with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Endoglin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HZW", "evidence_id": "EV-PDB-5HZW-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.451}, "provenance": {"deposit_id": "5HZW", "doi": "10.1016/j.celrep.2017.05.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HZW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the orphan region of human endoglin/CD105 in complex with BMP9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Tightly bound bacterial magnetic particle protein,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5I69", "evidence_id": "EV-PDB-5I69-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "5I69", "doi": "10.1016/j.jsb.2016.03.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5I69"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-MamC magnetite-interaction component mutant-D70A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GOL", "MPD", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -166.05}, "construct": {"description": "Maltose-binding periplasmic protein,Fimbrial protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IHJ", "evidence_id": "EV-PDB-5IHJ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "5IHJ", "doi": "10.1074/jbc.M116.751099", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IHJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii BIDMC57"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PGE", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Vitelline envelope sperm lysin receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5II5", "evidence_id": "EV-PDB-5II5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "5II5", "doi": "10.1016/j.cell.2017.05.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5II5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of red abalone VERL repeat 1 at 1.8 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Vitelline envelope sperm lysin receptor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IIC", "evidence_id": "EV-PDB-5IIC-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "5IIC", "doi": "10.1016/j.cell.2017.05.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IIC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of red abalone VERL repeat 3 at 2.9 A resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SIRT7 protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IQZ", "evidence_id": "EV-PDB-5IQZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.334}, "provenance": {"deposit_id": "5IQZ", "doi": "10.1002/prot.25085", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IQZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of N-terminal domain of Human SIRT7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Mitochondrial division protein 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JST", "evidence_id": "EV-PDB-5JST-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.199}, "provenance": {"deposit_id": "5JST", "doi": "10.1038/srep43318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JST"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP fused MDV1 coiled coil"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains B,E,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LEL", "evidence_id": "EV-PDB-5LEL-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "5LEL", "doi": "10.1038/s41598-017-11472-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LEL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_10_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5LEM", "evidence_id": "EV-PDB-5LEM-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "5LEM", "doi": "10.1038/s41598-017-11472-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5LEM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_11_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5M13", "evidence_id": "EV-PDB-5M13-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.372}, "provenance": {"deposit_id": "5M13", "doi": "10.7554/eLife.34317", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5M13"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Synthetic nanobody in complex with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5M15", "evidence_id": "EV-PDB-5M15-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "5M15", "doi": "10.7554/eLife.34317", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5M15"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Synthetic nanobody in complex with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Sugar ABC transporter substrate-binding protein,Magnetosome protein MamC,Sugar ABC transporter substrate-binding protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MM3", "evidence_id": "EV-PDB-5MM3-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "5MM3", "doi": "10.1107/S2059798317017491", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MM3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Unstructured MamC magnetite-binding protein located between two helices."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PGE", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Zona pellucida sperm-binding protein 3 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OSQ", "evidence_id": "EV-PDB-5OSQ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "5OSQ", "doi": "10.1038/NATURE07599", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OSQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ZP-N domain of mammalian sperm receptor ZP3 (crystal form II, processed in P21221)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A3P", "CL", "EDO", "NA", "NPO", "TLA", "branched: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltose binding protein - heparan sulfate 6-O-sulfotransferase isoform 3 fusion protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5T03", "evidence_id": "EV-PDB-5T03-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "5T03", "doi": "10.1021/acschembio.6b00841", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5T03"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A3P", "CL", "EDO", "NA", "NPO", "TLA", "branched: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltose binding protein - heparan sulfate 6-O-sulfotransferase isoform 3 fusion protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5T05", "evidence_id": "EV-PDB-5T05-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.952}, "provenance": {"deposit_id": "5T05", "doi": "10.1021/acschembio.6b00841", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5T05"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5V6Y", "evidence_id": "EV-PDB-5V6Y-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "5V6Y", "doi": "10.1124/mol.117.110916", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5V6Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CAC", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP fused activation-induced cytidine deaminase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W0R", "evidence_id": "EV-PDB-5W0R-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "5W0R", "doi": "10.1016/j.molcel.2017.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W0R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with cacodylic acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "DCM", "GOL", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Single-stranded DNA cytosine deaminase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W0U", "evidence_id": "EV-PDB-5W0U-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "5W0U", "doi": "10.1016/j.molcel.2017.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W0U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with dCMP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP fused activation-induced cytidine deaminase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W0Z", "evidence_id": "EV-PDB-5W0Z-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.61}, "provenance": {"deposit_id": "5W0Z", "doi": "10.1016/j.molcel.2017.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W0Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused activation-induced cytidine deaminase (AID)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP-hMNDA-PYD (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WPZ", "evidence_id": "EV-PDB-5WPZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "5WPZ", "doi": "10.1038/srep40991", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WPZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MNDA PYD with MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Two-component system sensor kinase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WVN", "evidence_id": "EV-PDB-5WVN-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "5WVN", "doi": "10.1002/prot.25326", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WVN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBS-BaeS fusion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Two-component system sensor kinase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WVM", "evidence_id": "EV-PDB-5WVM-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "5WVM", "doi": "10.1002/prot.25326", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WVM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of baeS cocrystallized with 2 mM indole"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP tagged hMNDA-PYD (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WQ6", "evidence_id": "EV-PDB-5WQ6-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.648}, "provenance": {"deposit_id": "5WQ6", "doi": "10.1038/srep40991", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WQ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of hMNDA-PYD with MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CTN", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP fused activation-induced cytidine deaminase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W1C", "evidence_id": "EV-PDB-5W1C-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "5W1C", "doi": "10.1016/j.molcel.2017.06.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W1C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with cytidine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GLU", "LYS", "MPD", "NA", "SER"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Type IV pilin PilA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VAW", "evidence_id": "EV-PDB-5VAW-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "5VAW", "doi": "10.1074/jbc.RA118.005814", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VAW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii AB5075"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Pilin isopeptide linkage domain protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5TTD", "evidence_id": "EV-PDB-5TTD-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "5TTD", "doi": "10.1038/srep42753", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5TTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Minor pilin FctB from S. pyogenes with engineered intramolecular isopeptide bond"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A3P", "CL", "EDO", "NA", "NPO", "TLA", "branched: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose", "branched: beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "maltose binding protein - heparan sulfate 6-O-sulfotransferase isoform 3 fusion protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5T0A", "evidence_id": "EV-PDB-5T0A-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "5T0A", "doi": "10.1021/acschembio.6b00841", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5T0A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5M14", "evidence_id": "EV-PDB-5M14-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "5M14", "doi": "10.7554/eLife.34317", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5M14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Synthetic nanobody in complex with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["B3P"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Protein translocase subunit SecA,Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5K94", "evidence_id": "EV-PDB-5K94-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "5K94", "doi": "10.1002/1873-3468.12832", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5K94"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Deletion-Insertion Chimera of MBP with the Preprotein Cross-Linking Domain of the SecA ATPase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Sugar ABC transporter substrate-binding protein,Caspase-8 chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5JQE", "evidence_id": "EV-PDB-5JQE-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.157}, "provenance": {"deposit_id": "5JQE", "doi": "10.1016/j.molcel.2016.09.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5JQE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of caspase8 tDED"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "PGE", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Endoglin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5I04", "evidence_id": "EV-PDB-5I04-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.42}, "provenance": {"deposit_id": "5I04", "doi": "10.1016/j.celrep.2017.05.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5I04"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the orphan region of human endoglin/CD105"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Endoglin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HZV", "evidence_id": "EV-PDB-5HZV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "5HZV", "doi": "10.1016/j.celrep.2017.05.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HZV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the zona pellucida module of human endoglin/CD105"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "PEG", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "NLRP12-PYD with MBP tag (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5H7N", "evidence_id": "EV-PDB-5H7N-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.849}, "provenance": {"deposit_id": "5H7N", "doi": "10.1038/srep40991", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5H7N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human NLRP12-PYD with a MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -83.15}, "construct": {"description": "Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GPQ", "evidence_id": "EV-PDB-5GPQ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "5GPQ", "doi": "10.1111/febs.14514", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of zebrafish ASC CARD Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -83.15}, "construct": {"description": "Maltose-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GPP", "evidence_id": "EV-PDB-5GPP-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "5GPP", "doi": "10.1111/febs.14514", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GPP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of zebrafish ASC PYD domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MALTOSE-BINDING PERIPLASMIC PROTEIN, HANTAVIRUS NUCLEOPROTEIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5FSG", "evidence_id": "EV-PDB-5FSG-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.209}, "provenance": {"deposit_id": "5FSG", "doi": "10.1016/J.CELREP.2016.02.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5FSG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation and a template for drug design"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5E24", "evidence_id": "EV-PDB-5E24-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.14}, "provenance": {"deposit_id": "5E24", "doi": "10.1371/journal.pbio.1002509", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5E24"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Su(H)-Hairless-DNA Repressor Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EYC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Maltose-binding periplasmic protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5CBN", "evidence_id": "EV-PDB-5CBN-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5CBN", "doi": "10.1038/ncomms11031", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5CBN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5BMY", "evidence_id": "EV-PDB-5BMY-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.001}, "provenance": {"deposit_id": "5BMY", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5BMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-21) fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "TNFRSF25 death domain (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5YEV", "evidence_id": "EV-PDB-5YEV-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "5YEV", "doi": "10.1111/febs.14834", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5YEV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Murine DR3 death domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Repressor protein cI,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ZCA", "evidence_id": "EV-PDB-5ZCA-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.801}, "provenance": {"deposit_id": "5ZCA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ZCA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of lambda repressor (1-20) fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FJV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6CXS", "evidence_id": "EV-PDB-6CXS-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "6CXS", "doi": "10.1073/pnas.1918095117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6CXS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EOH", "GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6D65", "evidence_id": "EV-PDB-6D65-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.348}, "provenance": {"deposit_id": "6D65", "doi": "10.1107/S2053230X18009901", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6D65"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein off7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DAL", "EDO", "GLY", "PEG", "PG4", "PGE", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6D66", "evidence_id": "EV-PDB-6D66-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.226}, "provenance": {"deposit_id": "6D66", "doi": "10.1107/S2053230X18009901", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6D66"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBL", "evidence_id": "EV-PDB-6DBL-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.0}, "provenance": {"deposit_id": "6DBL", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBQ", "evidence_id": "EV-PDB-6DBQ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.22}, "provenance": {"deposit_id": "6DBQ", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "LMT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Nanobody,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6HD8", "evidence_id": "EV-PDB-6HD8-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "6HD8", "doi": "10.7554/eLife.53683", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6HD8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the potassium channel MtTMEM175 in complex with a Nanobody-MBP fusion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LMT", "RB", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Nanobody,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6HD9", "evidence_id": "EV-PDB-6HD9-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "6HD9", "doi": "10.7554/eLife.53683", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6HD9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the potassium channel MtTMEM175 with rubidium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CS", "LMT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Nanobody,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6HDA", "evidence_id": "EV-PDB-6HDA-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "6HDA", "doi": "10.7554/eLife.53683", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6HDA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the potassium channel MtTMEM175 with cesium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "LMT", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Nanobody,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6HDB", "evidence_id": "EV-PDB-6HDB-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6HDB", "doi": "10.7554/eLife.53683", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6HDB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the potassium channel MtTMEM175 with zinc"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "LMT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Nanobody,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6HDC", "evidence_id": "EV-PDB-6HDC-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6HDC", "doi": "10.7554/eLife.53683", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6HDC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the potassium channel MtTMEM175 T38A variant in complex with a Nanobody-MBP fusion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Mitochondrial import inner membrane translocase subunit TIM21 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6K7D", "evidence_id": "EV-PDB-6K7D-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6K7D", "doi": "10.1016/j.bbagen.2019.129418", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6K7D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBPapo-Tim21 fusion protein with a 16-residue helical linker"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Mitochondrial import inner membrane translocase subunit TIM21 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6K7E", "evidence_id": "EV-PDB-6K7E-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.534}, "provenance": {"deposit_id": "6K7E", "doi": "10.1016/j.bbagen.2019.129418", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6K7E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBPapo-Tim21 fusion protein with a 17-residue helical linker"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "RAP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "chimera of Maltose/maltodextrin-binding periplasmic protein and Peptidyl-prolyl cis-trans isomerase FKBP1A (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6M4V", "evidence_id": "EV-PDB-6M4V-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "6M4V", "doi": "10.1038/s41592-020-0913-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6M4V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused split FKBP in complex with rapamycin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 10.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein-tyrosine kinase 2-beta (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6LF3", "evidence_id": "EV-PDB-6LF3-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "6LF3", "doi": "10.1038/s41598-019-56718-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6LF3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "3D domain-swapped dimer of the maltose-binding protein fused to a fragment of the protein-tyrosine kinase 2-beta"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 10.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Focal adhesion kinase 1 (chains A,B,X,Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6LES", "evidence_id": "EV-PDB-6LES-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.004}, "provenance": {"deposit_id": "6LES", "doi": "10.1038/s41598-019-56718-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6LES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "3D domain-swapped dimer of the maltose-binding protein fused to a fragment of the focal adhesion kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "caspase-11-CARD (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6KXG", "evidence_id": "EV-PDB-6KXG-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.805}, "provenance": {"deposit_id": "6KXG", "doi": "10.1038/s41421-020-00201-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6KXG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of caspase-11-CARD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -83.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6KI0", "evidence_id": "EV-PDB-6KI0-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6KI0", "doi": "10.1038/s41419-020-03342-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6KI0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human ASC-CARD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6KEA", "evidence_id": "EV-PDB-6KEA-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "6KEA", "doi": "10.1074/jbc.RA119.010123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6KEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "crystal structure of MBP-tagged REV7-IpaB complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Mitochondrial import inner membrane translocase subunit TIM21 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6K7F", "evidence_id": "EV-PDB-6K7F-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "6K7F", "doi": "10.1016/j.bbagen.2019.129418", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6K7F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBPholo-Tim21 fusion protein with a 17-residue helical linker"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose transport system, substrate-binding protein,TP53-regulated inhibitor of apoptosis 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6I4Y", "evidence_id": "EV-PDB-6I4Y-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "6I4Y", "doi": "10.1038/s41467-019-09089-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6I4Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the human mitochondrial PRELID3b-TRIAP1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Tightly bound bacterial magnetic particle protein,Maltose-binding periplasmic protein (chains A,B,D,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6EQZ", "evidence_id": "EV-PDB-6EQZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.293}, "provenance": {"deposit_id": "6EQZ", "doi": "10.1107/S2059798317017491", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6EQZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A MamC-MIC insertion in MBP scaffold at position K170"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EOH", "J7G"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6EG3", "evidence_id": "EV-PDB-6EG3-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "6EG3", "doi": "10.1021/acs.jmedchem.8b01318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6EG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human BRM in complex with compound 15"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IPA", "J7J"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6EG2", "evidence_id": "EV-PDB-6EG2-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "6EG2", "doi": "10.1021/acs.jmedchem.8b01318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6EG2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human BRM in complex with compound 16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6AK", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Induced myeloid leukemia cell differentiation protein Mcl-1 homolog - MBP chimera (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DM8", "evidence_id": "EV-PDB-6DM8-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "6DM8", "doi": "10.1021/acs.biochem.8b00626", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DM8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Understanding the Species Selectivity of Myeloid cell leukemia-1 (Mcl-1) inhibitors"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains D,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DKS", "evidence_id": "EV-PDB-6DKS-4", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "6DKS", "doi": "10.1016/j.celrep.2018.12.097", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DKS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Rbpj-SHARP-DNA Repressor Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MMB-1 Cas6 Fused to Maltose Binding Protein,CRISPR-associated endonuclease Cas1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DD5", "evidence_id": "EV-PDB-6DD5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "6DD5", "doi": "10.1016/j.molcel.2018.09.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DD5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBX", "evidence_id": "EV-PDB-6DBX-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "6DBX", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS substrate DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBW", "evidence_id": "EV-PDB-6DBW-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.7}, "provenance": {"deposit_id": "6DBW", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS substrate DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBV", "evidence_id": "EV-PDB-6DBV-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.29}, "provenance": {"deposit_id": "6DBV", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBV", "evidence_id": "EV-PDB-6DBV-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.29}, "provenance": {"deposit_id": "6DBV", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBU", "evidence_id": "EV-PDB-6DBU-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "6DBU", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBT", "evidence_id": "EV-PDB-6DBT-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "6DBT", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBR", "evidence_id": "EV-PDB-6DBR-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "6DBR", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBO", "evidence_id": "EV-PDB-6DBO-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "6DBO", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBJ", "evidence_id": "EV-PDB-6DBJ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "6DBJ", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Recombination activating gene 1 - MBP chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DBI", "evidence_id": "EV-PDB-6DBI-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6DBI", "doi": "10.1038/s41594-018-0098-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DBI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "PEG", "PO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6D67", "evidence_id": "EV-PDB-6D67-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "6D67", "doi": "10.1107/S2053230X18009901", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6D67"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion (maltose bound form) in complex with the designed AR protein mbp3_16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6D1U", "evidence_id": "EV-PDB-6D1U-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "6D1U", "doi": "10.1074/jbc.RA118.005062", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6D1U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer in complex with adrenomedullin 2/intermedin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein, Centromere protein N chimera (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6BUZ", "evidence_id": "EV-PDB-6BUZ-7", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.92}, "provenance": {"deposit_id": "6BUZ", "doi": "10.1126/science.aar2781", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6BUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6APX", "evidence_id": "EV-PDB-6APX-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.491}, "provenance": {"deposit_id": "6APX", "doi": "10.1002/pro.3328", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6APX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the monobody YSX1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "MES", "PEG", "PGE", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "anti-CRISPR protein AcrF1 fused with C-terminal MBP tag (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ANV", "evidence_id": "EV-PDB-6ANV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.265}, "provenance": {"deposit_id": "6ANV", "doi": "10.1016/j.cell.2017.09.006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ANV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of anti-CRISPR protein AcrF1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "Maltose-binding periplasmic protein,Trigger factor (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ZR0", "evidence_id": "EV-PDB-5ZR0-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "5ZR0", "doi": "10.1074/jbc.RA118.003579", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ZR0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of peptidyl-prolyl cis/trans isomerase domain of Trigger Factor in complex with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ZNZ", "evidence_id": "EV-PDB-5ZNZ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "5ZNZ", "doi": "10.1111/febs.14834", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ZNZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of mDR3 DD with MBP tag mutant-I387V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ZNY", "evidence_id": "EV-PDB-5ZNY-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74}, "provenance": {"deposit_id": "5ZNY", "doi": "10.1111/febs.14834", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ZNY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of mDR3_DD-C363G with MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Extracellular solute-binding protein family 1,viral genome protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5Z0V", "evidence_id": "EV-PDB-5Z0V-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.913}, "provenance": {"deposit_id": "5Z0V", "doi": "10.1038/s41422-018-0007-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5Z0V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural insight into the Zika virus capsid encapsulating the viral genome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Extracellular solute-binding protein family 1,viral genome protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5Z0R", "evidence_id": "EV-PDB-5Z0R-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "5Z0R", "doi": "10.1038/s41422-018-0007-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5Z0R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural insight into the Zika virus capsid encapsulating the viral genome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Human TNRSF25 death domain (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5YGS", "evidence_id": "EV-PDB-5YGS-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.691}, "provenance": {"deposit_id": "5YGS", "doi": "10.1111/febs.14834", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5YGS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human TNFRSF25 death domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "TNFRSF25 death domain (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5YGP", "evidence_id": "EV-PDB-5YGP-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.09}, "provenance": {"deposit_id": "5YGP", "doi": "10.1111/febs.14834", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5YGP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human TNFRSF25 death domain mutant-D412E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -83.15}, "construct": {"description": "Maltose-binding periplasmic protein,Protein B (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5Y2G", "evidence_id": "EV-PDB-5Y2G-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "5Y2G", "doi": "10.1107/S205979831901057X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5Y2G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP tagged GBS CAMP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JLE", "NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QZ7", "evidence_id": "EV-PDB-6QZ7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6QZ7", "doi": "10.1021/acs.jmedchem.9b00134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QZ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 8b"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,De novo design protein D53 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FBD", "evidence_id": "EV-PDB-7FBD-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7FBD", "doi": "10.1038/s41586-021-04383-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FBD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "De novo design protein D53 with MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.24, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,De novo design protein D22 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FBC", "evidence_id": "EV-PDB-7FBC-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "7FBC", "doi": "10.1038/s41586-021-04383-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FBC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "De novo design protein D22 with MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,de novo designed protein D12 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7FBB", "evidence_id": "EV-PDB-7FBB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.307}, "provenance": {"deposit_id": "7FBB", "doi": "10.1038/s41586-021-04383-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7FBB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "De novo design protein D12 with MBP tag"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7E29", "evidence_id": "EV-PDB-7E29-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.303}, "provenance": {"deposit_id": "7E29", "doi": "10.1093/nar/gkac077", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7E29"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein (chains A,C,E,G,I,K,M,O,Q,S,V,X)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DDE", "evidence_id": "EV-PDB-7DDE-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26}, "provenance": {"deposit_id": "7DDE", "doi": "10.15252/embj.2020107497", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DDE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Ape4 and Nbr1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DD9", "evidence_id": "EV-PDB-7DD9-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7DD9", "doi": "10.15252/embj.2020107497", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DD9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Ams1 and Nbr1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ASC", "EDO", "FE2", "IPA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -100.15}, "construct": {"description": "Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CY8", "evidence_id": "EV-PDB-7CY8-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7CY8", "doi": "10.1038/s41467-021-21061-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CY8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CMD1 in complex with 5mC-DNA and vitamin C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "FE2", "IPA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CY7", "evidence_id": "EV-PDB-7CY7-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "7CY7", "doi": "10.1038/s41467-021-21061-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CY7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CMD1 in complex with DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "FE2", "PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CY6", "evidence_id": "EV-PDB-7CY6-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "7CY6", "doi": "10.1038/s41467-021-21061-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CY6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CMD1 in complex with 5mC-DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ASC", "CIT", "FE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CY5", "evidence_id": "EV-PDB-7CY5-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "7CY5", "doi": "10.1038/s41467-021-21061-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CY5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CMD1 in complex with vitamin C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "FE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CY4", "evidence_id": "EV-PDB-7CY4-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "7CY4", "doi": "10.1038/s41467-021-21061-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CY4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of CMD1 in apo form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose Binding Protein tag, linker,CENP-C (chains K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BY0", "evidence_id": "EV-PDB-7BY0-7", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "7BY0", "doi": "10.15252/embj.2020105671", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BY0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of CENP-A nucleosome in complex with the phosphorylated CENP-C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,Centromere protein N (chains M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BXT", "evidence_id": "EV-PDB-7BXT-8", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7BXT", "doi": "10.15252/embj.2020105671", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BXT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of CENP-A nucleosome in complex with CENP-C peptide and CENP-N N-terminal domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Islet amyloid polypeptide (chains A,B,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BG0", "evidence_id": "EV-PDB-7BG0-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "7BG0", "doi": "10.1021/acs.jmedchem.1c00565", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BG0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fusion of MBP and the backbone of the long-acting amylin analog AM833."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Maltodextrin-binding protein,Maltodextrin-binding protein,ADAMTS13 CUB12,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B01", "evidence_id": "EV-PDB-7B01-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7B01", "doi": "10.1126/sciadv.abg4403", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B01"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ADAMTS13-CUB12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PG4", "QLQ", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZHO", "evidence_id": "EV-PDB-6ZHO-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "6ZHO", "doi": "10.1021/acs.jmedchem.0c01003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZHO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a CGRP receptor ectodomain heterodimer with bound high affinity inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PJQ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YSN", "evidence_id": "EV-PDB-6YSN-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "6YSN", "doi": "10.1038/s42003-020-01437-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YSN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human TRPC5 in complex with Pico145 (HC-608)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["OK5", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YBL", "evidence_id": "EV-PDB-6YBL-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "6YBL", "doi": "10.1021/acs.jmedchem.0c01234", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YBL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 9m"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "OK2", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YBK", "evidence_id": "EV-PDB-6YBK-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6YBK", "doi": "10.1021/acs.jmedchem.0c01234", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YBK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 4d"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "OJW", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YBJ", "evidence_id": "EV-PDB-6YBJ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6YBJ", "doi": "10.1021/acs.jmedchem.0c01234", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YBJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 3e"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein, Mosquito protein AZ1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XRX", "evidence_id": "EV-PDB-6XRX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "6XRX", "doi": "10.1073/pnas.2019251118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XRX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the mosquito protein AZ1 as an MBP fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "V5S", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Sugar ABC transporter substrate-binding protein,Triggering receptor expressed on myeloid cells 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XDS", "evidence_id": "EV-PDB-6XDS-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.466}, "provenance": {"deposit_id": "6XDS", "doi": "10.1016/j.pep.2020.105796", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XDS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-TREM2 Ig domain fusion with fragment, 2-((4-bromophenyl)amino)ethan-1-ol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAC", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein, C->U-editing enzyme APOBEC-1 chimera (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6X91", "evidence_id": "EV-PDB-6X91-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "6X91", "doi": "10.1093/narcan/zcaa027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6X91"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused human APOBEC1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6WGZ", "evidence_id": "EV-PDB-6WGZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6WGZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6WGZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HyBcl-2-4 with HyBak1 BH3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Reversion-inducing cysteine-rich protein with Kazal motifs fusion (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6WBJ", "evidence_id": "EV-PDB-6WBJ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.651}, "provenance": {"deposit_id": "6WBJ", "doi": "10.1073/pnas.2006332117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6WBJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "High resolution crystal structure of mRECK(CC4) in fusion with engineered MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Reversion-inducing cysteine-rich protein with Kazal motifs fusion (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6WBH", "evidence_id": "EV-PDB-6WBH-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.455}, "provenance": {"deposit_id": "6WBH", "doi": "10.1073/pnas.2006332117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6WBH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of mRECK(CC4) in fusion with engineered MBP at medium resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Vip3Aa (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VLS", "evidence_id": "EV-PDB-6VLS-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "6VLS", "doi": "10.3390/toxins12070438", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VLS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of C-terminal fragment of Vip3A toxin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT", "NH2", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.3, "salt_mM": null, "temperature_c": -168.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 2,Calcitonin gene-related peptide type 1 receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6V2E", "evidence_id": "EV-PDB-6V2E-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "6V2E", "doi": "10.1021/acsptsci.0c00031", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6V2E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6USM", "evidence_id": "EV-PDB-6USM-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.37}, "provenance": {"deposit_id": "6USM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6USM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of nuclease domain of human parvovirus B19 non-structural protein 1 in complex with zinc"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6TZC", "evidence_id": "EV-PDB-6TZC-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.41}, "provenance": {"deposit_id": "6TZC", "doi": "10.3390/v11090789", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6TZC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "LMT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Nanobody, Maltose/maltodextrin-binding periplasmic protein,Maltodextrin-binding protein,Maltose/maltodextrin-binding periplasmic protein (chains A,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SWR", "evidence_id": "EV-PDB-6SWR-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "6SWR", "doi": "10.7554/eLife.53683", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SWR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the lysosomal potassium channel MtTMEM175 T38A mutant soaked with zinc"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,CREB-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SQC", "evidence_id": "EV-PDB-6SQC-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.28}, "provenance": {"deposit_id": "6SQC", "doi": "10.1039/d0sc04482b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SQC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR containing alpha-methylated Leu1055 and Leu1076"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PEG", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein E6,Mastermind-like protein 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SMV", "evidence_id": "EV-PDB-6SMV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.14}, "provenance": {"deposit_id": "6SMV", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SMV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of HPV49 E6 protein in complex with MAML1 LxxLL motif"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein E6,Ubiquitin-protein ligase E3A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SLM", "evidence_id": "EV-PDB-6SLM-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "6SLM", "doi": "10.1128/JVI.00730-20", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SLM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of full-length HPV31 E6 oncoprotein in complex with LXXLL peptide of ubiquitin ligase E6AP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SJA", "evidence_id": "EV-PDB-6SJA-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "6SJA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SJA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of HPV16 E6 oncoprotein in complex with IRF3 LxxLL motif"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SIV", "evidence_id": "EV-PDB-6SIV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.752}, "provenance": {"deposit_id": "6SIV", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SIV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of HPV16 E6 oncoprotein in complex with mutant IRF3 LxxLL motif"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JLH", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QYO", "evidence_id": "EV-PDB-6QYO-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "6QYO", "doi": "10.1021/acs.jmedchem.9b00134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 18a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JL8", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QYN", "evidence_id": "EV-PDB-6QYN-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6QYN", "doi": "10.1021/acs.jmedchem.9b00134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QYN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 10d"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JLE", "NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QYL", "evidence_id": "EV-PDB-6QYL-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6QYL", "doi": "10.1021/acs.jmedchem.9b00134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QYL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 8a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JLB", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QYK", "evidence_id": "EV-PDB-6QYK-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "6QYK", "doi": "10.1021/acs.jmedchem.9b00134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QYK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 7a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JKQ", "NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QXJ", "evidence_id": "EV-PDB-6QXJ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "6QXJ", "doi": "10.1021/acs.jmedchem.9b00134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QXJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with compound 6a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CU", "PO4", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Nucleoporin, putative (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QUG", "evidence_id": "EV-PDB-6QUG-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "6QUG", "doi": "10.1107/S2059798320013741", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QUG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GHK tagged MBP-Nup98(1-29)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["J1N", "NA", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QGD", "evidence_id": "EV-PDB-6QGD-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "6QGD", "doi": "10.1021/acsomega.9b00611", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QGD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of human Mcl-1 in complex with thienopyrimidine inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6P6W", "evidence_id": "EV-PDB-6P6W-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "6P6W", "doi": "10.1016/j.cell.2019.06.031", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6P6W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FPP", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6OB5", "evidence_id": "EV-PDB-6OB5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.208}, "provenance": {"deposit_id": "6OB5", "doi": "10.1126/science.aax8780", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6OB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Computationally-designed, modular sense/response system (S3-2D)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6NDJ", "evidence_id": "EV-PDB-6NDJ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.27}, "provenance": {"deposit_id": "6NDJ", "doi": "10.1073/pnas.1817221116", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6NDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human NLRP6 PYD domain with MBP fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2 (chains M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N85", "evidence_id": "EV-PDB-6N85-2", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6N85", "doi": "10.1038/s41467-019-11088-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N85"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Resistance to inhibitors of cholinesterase 8A (Ric8A) protein in complex with MBP-tagged transducin-alpha residues 327-350"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N84", "evidence_id": "EV-PDB-6N84-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "6N84", "doi": "10.1038/s41467-019-11088-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N84"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-fusion protein of transducin-alpha residues 327-350"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "RAP", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "chimera of Maltose/maltodextrin-binding periplasmic protein and Peptidyl-prolyl cis-trans isomerase FKBP1A (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6M4W", "evidence_id": "EV-PDB-6M4W-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "6M4W", "doi": "10.1038/s41592-020-0913-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6M4W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused split FKBP-FRB T2098L mutant in complex with rapamycin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Protein phosphatase 1 regulatory subunit 15A,Maltose/maltodextrin-binding periplasmic protein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NZM", "evidence_id": "EV-PDB-7NZM-5", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.96}, "provenance": {"deposit_id": "7NZM", "doi": "10.1038/s41594-021-00666-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NZM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT0", "evidence_id": "EV-PDB-7TT0-5", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7TT0", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP class 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT6", "evidence_id": "EV-PDB-7TT6-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7TT6", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP in the intermediate-open EspP state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT7", "evidence_id": "EV-PDB-7TT7-5", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8}, "provenance": {"deposit_id": "7TT7", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP in the barrelized EspP/continuous open BamA state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein E6 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UAJ", "evidence_id": "EV-PDB-7UAJ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "7UAJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UAJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of apo HPV16 E6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NCA", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "MBP-fused OspC3 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WR3", "evidence_id": "EV-PDB-7WR3-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.87}, "provenance": {"deposit_id": "7WR3", "doi": "10.1038/s41594-022-00888-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WR3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused OspC3 in complex with calmodulin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,Gastrin-releasing peptide receptor (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7W40", "evidence_id": "EV-PDB-7W40-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7W40", "doi": "10.1073/pnas.2216230120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7W40"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Bombesin (6-14) [D-Phe6, beta-Ala11, Phe13, Nle14] and Gq heterotrimers"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,Gastrin-releasing peptide receptor (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7W3Z", "evidence_id": "EV-PDB-7W3Z-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7W3Z", "doi": "10.1073/pnas.2216230120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7W3Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Gastrin Releasing Peptide and Gq heterotrimers"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ams1, Nbr1 and malE fusion protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VQO", "evidence_id": "EV-PDB-7VQO-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.19}, "provenance": {"deposit_id": "7VQO", "doi": "10.1038/s41467-022-31439-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VQO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Ams1 bound to the FW domain of Nbr1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VN8", "evidence_id": "EV-PDB-7VN8-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.04}, "provenance": {"deposit_id": "7VN8", "doi": "10.1038/s41477-022-01289-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VN8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning GTCACGTGAC"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VN7", "evidence_id": "EV-PDB-7VN7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.11}, "provenance": {"deposit_id": "7VN7", "doi": "10.1038/s41477-022-01289-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VN7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning GACACGTGTC"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VN6", "evidence_id": "EV-PDB-7VN6-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "7VN6", "doi": "10.1038/s41477-022-01289-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning CGCACGTGCG"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VN5", "evidence_id": "EV-PDB-7VN5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "7VN5", "doi": "10.1038/s41477-022-01289-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning TTCACGTGAA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VN4", "evidence_id": "EV-PDB-7VN4-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "7VN4", "doi": "10.1038/s41477-022-01289-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VN4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning TCCACGTGGA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VN3", "evidence_id": "EV-PDB-7VN3-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "7VN3", "doi": "10.1038/s41477-022-01289-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VN3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning CACACGTGTG"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -178.15}, "construct": {"description": "Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VN2", "evidence_id": "EV-PDB-7VN2-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.42}, "provenance": {"deposit_id": "7VN2", "doi": "10.1038/s41477-022-01289-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning ATCACGTGAT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VH1", "evidence_id": "EV-PDB-7VH1-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7VH1", "doi": "10.1038/s41467-021-26432-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VH1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Machupo virus dimeric L-Z complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VGQ", "evidence_id": "EV-PDB-7VGQ-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7VGQ", "doi": "10.1038/s41467-021-26432-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VGQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Machupo virus polymerase L in complex with matrix protein Z"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,POU domain, class 5, transcription factor 1 (chains L,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U0I", "evidence_id": "EV-PDB-7U0I-7", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7U0I", "doi": "10.1016/j.molcel.2023.05.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U0I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of LIN28b nucleosome bound 2 OCT4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,POU domain, class 5, transcription factor 1 (chains K,L,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U0G", "evidence_id": "EV-PDB-7U0G-7", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7U0G", "doi": "10.1016/j.molcel.2023.05.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U0G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "structure of LIN28b nucleosome bound 3 OCT4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT5", "evidence_id": "EV-PDB-7TT5-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7TT5", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP in the open-sheet EspP state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT4", "evidence_id": "EV-PDB-7TT4-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7TT4", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP class 6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT3", "evidence_id": "EV-PDB-7TT3-6", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7TT3", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP class 5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT2", "evidence_id": "EV-PDB-7TT2-6", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7TT2", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP class 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TT1", "evidence_id": "EV-PDB-7TT1-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7TT1", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TT1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP class 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TSZ", "evidence_id": "EV-PDB-7TSZ-6", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "7TSZ", "doi": "10.1016/j.cell.2022.02.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TSZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BamABCDE bound to substrate EspP class 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Putative pilin protein chimera (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T31", "evidence_id": "EV-PDB-7T31-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7T31", "doi": "10.1016/j.jbc.2022.102449", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T31"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray Structure of Clostridiodies difficile PilW"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Ribonucleoside-diphosphate reductase large subunit (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RW6", "evidence_id": "EV-PDB-7RW6-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "7RW6", "doi": "10.1126/sciadv.abm2827", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RW6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BORF2-APOBEC3Bctd Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,Autotransporter outer membrane beta-barrel domain-containing protein chimera (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RJ5", "evidence_id": "EV-PDB-7RJ5-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.0}, "provenance": {"deposit_id": "7RJ5", "doi": "10.1038/s41467-021-27449-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RJ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of BAM in complex with EspP at 7 Angstrom resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,RTX-toxin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P1H", "evidence_id": "EV-PDB-7P1H-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7P1H", "doi": "10.1038/s41467-021-26889-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P1H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the V. vulnificus ExoY-G-actin-profilin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "GH3", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Adenylate cyclase ExoY (chains K,L,M,N,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P1G", "evidence_id": "EV-PDB-7P1G-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7P1G", "doi": "10.1038/s41467-021-26889-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P1G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the P. aeruginosa ExoY-F-actin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["7IU", "PG4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P0I", "evidence_id": "EV-PDB-7P0I-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7P0I", "doi": "10.1021/acschemneuro.1c00696", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P0I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor Compound 13"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["7IR", "PG4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P0F", "evidence_id": "EV-PDB-7P0F-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "7P0F", "doi": "10.1021/acschemneuro.1c00696", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0028125"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "P6G", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "ProMacrobody 21 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OMT", "evidence_id": "EV-PDB-7OMT-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "7OMT", "doi": "10.1038/s41467-022-29459-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OMT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of ProMacrobody 21 with bound maltose"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ProMacrobody 51,Maltodextrin-binding protein (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OMM", "evidence_id": "EV-PDB-7OMM-4", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7OMM", "doi": "10.1038/s41467-022-29459-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OMM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of N. gonorhoeae LptDE in complex with ProMacrobodies (MBPs have not been built de novo)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ProMacrobody 21,Maltodextrin-binding protein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OMM", "evidence_id": "EV-PDB-7OMM-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7OMM", "doi": "10.1038/s41467-022-29459-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OMM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of N. gonorhoeae LptDE in complex with ProMacrobodies (MBPs have not been built de novo)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Guanine nucleotide exchange protein SMCR8,Guanine nucleotide exchange protein SMCR8,Maltose/maltodextrin-binding periplasmic protein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7O2W", "evidence_id": "EV-PDB-7O2W-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7O2W", "doi": "10.1371/journal.pbio.3001344", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7O2W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the C9orf72-SMCR8 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MQ7", "evidence_id": "EV-PDB-7MQ7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "7MQ7", "doi": "10.1002/bit.27927", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MQ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Tetragonal Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AU", "CL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MQ6", "evidence_id": "EV-PDB-7MQ6-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.372}, "provenance": {"deposit_id": "7MQ6", "doi": "10.1002/bit.27927", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MQ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Tetragonal Maltose Binding Protein in the presence of gold"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Receptor tyrosine-protein kinase erbB-2,Maltose/maltodextrin-binding periplasmic protein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MN8", "evidence_id": "EV-PDB-7MN8-3", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "7MN8", "doi": "10.1038/s41586-021-04084-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MN8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain bound to Trastuzumab Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Receptor tyrosine-protein kinase erbB-2,Maltose/maltodextrin-binding periplasmic protein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MN6", "evidence_id": "EV-PDB-7MN6-2", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09}, "provenance": {"deposit_id": "7MN6", "doi": "10.1038/s41586-021-04084-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the HER2 S310F/HER3/NRG1b Heterodimer Extracellular Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Receptor tyrosine-protein kinase erbB-2,Maltose/maltodextrin-binding periplasmic protein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MN5", "evidence_id": "EV-PDB-7MN5-3", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.93}, "provenance": {"deposit_id": "7MN5", "doi": "10.1038/s41586-021-04084-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ALK and LTK ligand 1,Maltodextrin-binding protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MK7", "evidence_id": "EV-PDB-7MK7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.42815184462}, "provenance": {"deposit_id": "7MK7", "doi": "10.1038/s41586-021-04141-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MK7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Augmentor domain of augmentor-beta"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Outer membrane lipoprotein omp19 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MHW", "evidence_id": "EV-PDB-7MHW-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "7MHW", "doi": "10.1016/j.csbj.2022.08.054", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MHW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the protease inhibitor U-Omp19 from Brucella abortus fused to Maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "AMP", "ATP", "TAK", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin ABC transporter substrate-binding protein MalE (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M74", "evidence_id": "EV-PDB-7M74-4", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.93}, "provenance": {"deposit_id": "7M74", "doi": "10.1126/science.abe7565", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M74"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ATP-bound AMP-activated protein kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Maltodextrin-binding protein and Phosphoprotein fusion protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KD4", "evidence_id": "EV-PDB-7KD4-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.312}, "provenance": {"deposit_id": "7KD4", "doi": "10.3390/v13091737", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KD4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the C-terminal domain of the Menangle virus phosphoprotein (residues 329 -388), fused to MBP. Space group P21."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K48", "evidence_id": "EV-PDB-7K48-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7K48", "doi": "10.1016/j.molcel.2020.10.039", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K48"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JTR", "evidence_id": "EV-PDB-7JTR-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7JTR", "doi": "10.1002/pro.4088", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JTR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex of maltose-binding protein (MBP) with single-chain Fv (scFv)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "AMP", "ATP", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin ABC transporter substrate-binding protein MalE (chains M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JIJ", "evidence_id": "EV-PDB-7JIJ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.5}, "provenance": {"deposit_id": "7JIJ", "doi": "10.1126/science.abe7565", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JIJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ATP-bound AMP-activated protein kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "AMP", "ATP", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JHH", "evidence_id": "EV-PDB-7JHH-4", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.92}, "provenance": {"deposit_id": "7JHH", "doi": "10.1126/science.abe7565", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JHH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Fab and nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "AMP", "ATP", "TAK", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JHG", "evidence_id": "EV-PDB-7JHG-4", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "7JHG", "doi": "10.1126/science.abe7565", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JHG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Dorsomorphin (Compound C) and Fab-nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["OK5", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EKX", "evidence_id": "EV-PDB-8EKX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "8EKX", "doi": "10.1038/s43856-023-00380-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EKX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with MIK665"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["WLW", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EL0", "evidence_id": "EV-PDB-8EL0-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.917}, "provenance": {"deposit_id": "8EL0", "doi": "10.1038/s43856-023-00380-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EL0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with a macrocyclic compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["WME", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EL1", "evidence_id": "EV-PDB-8EL1-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.406}, "provenance": {"deposit_id": "8EL1", "doi": "10.1038/s43856-023-00380-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EL1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MBP-Mcl-1 in complex with ABBV-467"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CDL", "GTP", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pro-Macrobody 65, Maltose/maltodextrin-binding periplasmic protein chimera (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G8W", "evidence_id": "EV-PDB-8G8W-3", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8G8W", "doi": "10.1126/sciadv.adh4251", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G8W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Molecular mechanism of nucleotide inhibition of human uncoupling protein 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CDL", "GTP", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pro-macrobody 71, Maltose/maltodextrin-binding periplasmic protein chimera (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G8W", "evidence_id": "EV-PDB-8G8W-2", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8G8W", "doi": "10.1126/sciadv.adh4251", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G8W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Molecular mechanism of nucleotide inhibition of human uncoupling protein 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein E6 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GCR", "evidence_id": "EV-PDB-8GCR-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "8GCR", "doi": "10.1038/s41467-024-45920-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GCR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "HPV16 E6-E6AP-p53 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SBU", "evidence_id": "EV-PDB-8SBU-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8SBU", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fusion with HPPK from Methanocaldococcus jannaschii"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,EspP(b7-12) (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SQB", "evidence_id": "EV-PDB-8SQB-6", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8SQB", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SQB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the EcBAM/EspP(beta7-12) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP and AF9 AHD fusion protein 3AQA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TLW", "evidence_id": "EV-PDB-8TLW-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.106}, "provenance": {"deposit_id": "8TLW", "doi": "10.1002/pro.5019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TLW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 28"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GSH", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP and AF9 AHD fusion protein 4AQK (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TLV", "evidence_id": "EV-PDB-8TLV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.659}, "provenance": {"deposit_id": "8TLV", "doi": "10.1002/pro.5019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TLV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP and AF9 AHD fusion protein 4AQK in complex with peptidomimetic inhibitor 28"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "MG", "PGE", "YI7", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein/Induced myeloid leukemia cell differentiation protein Mcl-1 Chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T6F", "evidence_id": "EV-PDB-8T6F-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.56}, "provenance": {"deposit_id": "8T6F", "doi": "10.1038/s43018-024-00814-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T6F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human MBP-Myeloid cell leukemia 1 (Mcl-1) in complex with BRD810 inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T2I", "evidence_id": "EV-PDB-8T2I-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 10.4}, "provenance": {"deposit_id": "8T2I", "doi": "10.1016/j.xplc.2023.100639", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T2I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Negative stain EM assembly of MYC, JAZ, and NINJA complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "GOL", "WUC", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein, Induced myeloid leukemia cell differentiation protein Mcl-1 chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SVY", "evidence_id": "EV-PDB-8SVY-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.47}, "provenance": {"deposit_id": "8SVY", "doi": "10.1021/acsmedchemlett.3c00141", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SVY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MBP-Mcl1 in complex with ligand 10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Autotransporter protein EspP translocator (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SQA", "evidence_id": "EV-PDB-8SQA-6", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "8SQA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SQA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the EcBAM/EspP(beta8-12) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CST complex subunit CTC1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SOK", "evidence_id": "EV-PDB-8SOK-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "8SOK", "doi": "10.1016/j.cell.2024.05.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SOK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CST complex subunit CTC1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SOJ", "evidence_id": "EV-PDB-8SOJ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8SOJ", "doi": "10.1016/j.cell.2024.05.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SOJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the absence of telomeric ssDNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["WXW", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QSO", "evidence_id": "EV-PDB-8QSO-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.106}, "provenance": {"deposit_id": "8QSO", "doi": "10.1021/acs.jmedchem.3c02206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QSO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human Mcl-1 in complex with compound 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Gasdermin-like protein rcd-1-1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYX", "evidence_id": "EV-PDB-8JYX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "8JYX", "doi": "10.1126/science.adm9190", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the gasdermin-like protein RCD-1-1 from Neurospora crassa"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["V6X"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JXS", "evidence_id": "EV-PDB-8JXS-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8JXS", "doi": "10.1016/j.neuron.2024.07.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JXS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of nanobody-bound DRD1_PF-6142 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["7LD", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JXR", "evidence_id": "EV-PDB-8JXR-3", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.57}, "provenance": {"deposit_id": "8JXR", "doi": "10.1016/j.neuron.2024.07.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JXR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of nanobody-bound DRD1_LSD complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Hemorrhagic toxin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JI0", "evidence_id": "EV-PDB-8JI0-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8JI0", "doi": "10.1038/s41467-024-46394-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JI0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the TcsH-CROP in complex with TMPRSS2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein PML (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J2P", "evidence_id": "EV-PDB-8J2P-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.09}, "provenance": {"deposit_id": "8J2P", "doi": "10.1158/2159-8290.CD-23-0453", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J2P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of PML B-box2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein PML (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J25", "evidence_id": "EV-PDB-8J25-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8J25", "doi": "10.1158/2159-8290.CD-23-0453", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of PML B-box2 mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,YEATS domain-containing protein 4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IIZ", "evidence_id": "EV-PDB-8IIZ-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8IIZ", "doi": "10.1073/pnas.2304103120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IIZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,YEATS domain-containing protein 4 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IIY", "evidence_id": "EV-PDB-8IIY-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "8IIY", "doi": "10.1073/pnas.2304103120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IIY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Tumor necrosis factor receptor superfamily member 1B,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HLB", "evidence_id": "EV-PDB-8HLB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "8HLB", "doi": "10.1038/s42003-023-05326-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HLB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HGH", "evidence_id": "EV-PDB-8HGH-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.16}, "provenance": {"deposit_id": "8HGH", "doi": "10.1038/s41421-022-00502-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HGH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of 2:2 PAPP-A.STC2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EPE", "GLY", "MG", "OGA", "PEG", "TRS", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,DNA N6-methyl adenine demethylase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H68", "evidence_id": "EV-PDB-8H68-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8H68", "doi": "10.1093/jmcb/mjad008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H68"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein (Fragment),OrfB_Zn_ribbon domain-containing protein (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GKH", "evidence_id": "EV-PDB-8GKH-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8GKH", "doi": "10.1038/s41586-023-06356-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GKH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein, phiPA3 PhuN (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,a,b,c,d,e,f)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FV5", "evidence_id": "EV-PDB-8FV5-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.21}, "provenance": {"deposit_id": "8FV5", "doi": "10.1038/s41467-023-36526-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FV5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Representation of 16-mer phiPA3 PhuN Lattice, p2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein, PhuN (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FNE", "evidence_id": "EV-PDB-8FNE-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8FNE", "doi": "10.1038/s41467-023-36526-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FNE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "phiPA3 PhuN Tetramer, p2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Zinc Sensor protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F23", "evidence_id": "EV-PDB-8F23-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.93}, "provenance": {"deposit_id": "8F23", "doi": "10.1039/d3sc00437f", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F23"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of a rationally designed zinc sensor based on maltose binding protein - Apo conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Zinc Sensor protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ETB", "evidence_id": "EV-PDB-8ETB-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.63}, "provenance": {"deposit_id": "8ETB", "doi": "10.1039/d3sc00437f", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ETB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "the crystal structure of a rationally designed zinc sensor based on maltose binding protein - Zn binding conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "EPE", "PEG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltodextrin-binding protein,Putative pilin protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DX4", "evidence_id": "EV-PDB-8DX4-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.487}, "provenance": {"deposit_id": "8DX4", "doi": "10.1016/j.jbc.2022.102449", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DX4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Clostridioides difficile R20291 minor pilin - PilW fused with Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PEG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Chromatin assembly factor 1 subunit p90 fusion (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DEI", "evidence_id": "EV-PDB-8DEI-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "8DEI", "doi": "10.7554/eLife.83538", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DEI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Cac1 KER domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Type III secretion protein PcrV (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CRB", "evidence_id": "EV-PDB-8CRB-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "8CRB", "doi": "10.1016/j.cell.2023.10.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CRB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of PcrV/Fab(11-E5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Type III secretion protein PcrV (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CR9", "evidence_id": "EV-PDB-8CR9-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "8CR9", "doi": "10.1016/j.cell.2023.10.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CR9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of PcrV/Fab(30-B8)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Apolipoprotein E (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CE0", "evidence_id": "EV-PDB-8CE0-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "8CE0", "doi": "10.1186/s13024-023-00620-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CE0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "N-terminal domain of human apolipoprotein E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein,Apolipoprotein E (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CDY", "evidence_id": "EV-PDB-8CDY-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8CDY", "doi": "10.1186/s13024-023-00620-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CDY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "N-terminal domain of human apolipoprotein E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C8F", "evidence_id": "EV-PDB-8C8F-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.15}, "provenance": {"deposit_id": "8C8F", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C8F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the E. coli maltodextrin-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Nuclear receptor subfamily 2 group F member 6 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C5L", "evidence_id": "EV-PDB-8C5L-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8C5L", "doi": "10.1021/acschembio.5c00475", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C5L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "NR2F6 ligand binding domain in complex with NSD1 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Apolipoprotein E (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AX9", "evidence_id": "EV-PDB-8AX9-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.549}, "provenance": {"deposit_id": "8AX9", "doi": "10.1186/s13024-023-00620-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Apolipoprotein E4 (ApoE4) N-terminal domain (space group P212121)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Apolipoprotein E (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AX8", "evidence_id": "EV-PDB-8AX8-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.551}, "provenance": {"deposit_id": "8AX8", "doi": "10.1186/s13024-023-00620-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AX8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Apolipoprotein E4 (ApoE4) N-terminal domain (space group P3121)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "OL0", "PG4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AX7", "evidence_id": "EV-PDB-8AX7-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "8AX7", "doi": "10.1021/acsmedchemlett.2c00400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0031448"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["OP9", "PG4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AX6", "evidence_id": "EV-PDB-8AX6-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8AX6", "doi": "10.1021/acsmedchemlett.2c00400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AX6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029882"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["OKU", "PG4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AX5", "evidence_id": "EV-PDB-8AX5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "8AX5", "doi": "10.1021/acsmedchemlett.2c00400", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0029881"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,TP53-regulated inhibitor of apoptosis 1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AG0", "evidence_id": "EV-PDB-8AG0-2", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8AG0", "doi": "10.1016/j.bbapap.2022.140867", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AG0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of mutant PRELID3a-TRIAP1 complex - R53E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "APR", "MG", "NCA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,TccC3 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z7H", "evidence_id": "EV-PDB-7Z7H-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7Z7H", "doi": "10.1038/s41467-022-31836-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z7H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of P. luminescens TccC3-F-actin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y5Q", "evidence_id": "EV-PDB-7Y5Q-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7Y5Q", "doi": "10.1038/s41421-022-00502-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y5Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of 1:1 PAPP-A.STC2 complex(half map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fusion protein of Maltose-binding periplasmic protein and RNA-binding protein KhpA (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XQC", "evidence_id": "EV-PDB-7XQC-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7XQC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XQC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of N-terminal domain of Rv2908c fused with Maltose Binding Protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MES", "NAG", "NNH", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltodextrin-binding protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XMN", "evidence_id": "EV-PDB-7XMN-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7XMN", "doi": "10.1128/spectrum.01234-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XMN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 ORF8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MBP and AF9 AHD fusion protein 3AQA (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TLX", "evidence_id": "EV-PDB-8TLX-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.097}, "provenance": {"deposit_id": "8TLX", "doi": "10.1002/pro.5019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TLX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 21a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["Y70", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,SD40 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TNP", "evidence_id": "EV-PDB-8TNP-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8TNP", "doi": "10.1126/science.adk4422", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TNP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of DDB1dB:CRBN:Pomalidomide:SD40"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MIQ", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,SD40 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TNQ", "evidence_id": "EV-PDB-8TNQ-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.41}, "provenance": {"deposit_id": "8TNQ", "doi": "10.1126/science.adk4422", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TNQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of DDB1dB:CRBN:PT-179:SD40, conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MIQ", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,SD40 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TNR", "evidence_id": "EV-PDB-8TNR-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8TNR", "doi": "10.1126/science.adk4422", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of DDB1dB:CRBN:PT-179:SD40, conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Transcription factor GATA-4 (chains T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VG0", "evidence_id": "EV-PDB-8VG0-7", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "8VG0", "doi": "10.1016/j.molcel.2024.07.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VG0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of GATA4 in complex with ALBN1 nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein fused to apoptosis regulator Bcl-2/Bcl-xL chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VWX", "evidence_id": "EV-PDB-8VWX-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.77}, "provenance": {"deposit_id": "8VWX", "doi": "10.1021/acs.analchem.4c04516", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VWX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Bcl-2 (G101V Mutant)/Bcl-xL Chimera Fused to Maltose-Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F3Q", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein fused to apoptosis regulator Bcl-2/Bcl-xL chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VXM", "evidence_id": "EV-PDB-8VXM-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8VXM", "doi": "10.1021/acs.analchem.4c04516", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VXM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Bcl-2/Bcl-xL Chimera Fused to MBP in Complex with Inhibitor S55746"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6 (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X2X", "evidence_id": "EV-PDB-8X2X-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8X2X", "doi": "10.1073/pnas.2414490122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X2X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The piccolo NuA4 bound to the H2A.Z nucleosome complex at pre-H4-acetylation state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6 (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X2Y", "evidence_id": "EV-PDB-8X2Y-6", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "8X2Y", "doi": "10.1073/pnas.2414490122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X2Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The class1 of piccolo NuA4 bound to the H2A.Z nucleosome complex at harboring state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 5 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7V", "evidence_id": "EV-PDB-8X7V-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "8X7V", "doi": "10.1038/s41594-024-01396-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SCMC ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 5 (chains A,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7W", "evidence_id": "EV-PDB-8X7W-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "8X7W", "doi": "10.1038/s41594-024-01396-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of dimeric human SCMC complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YBE", "evidence_id": "EV-PDB-8YBE-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8YBE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YBE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,N-terminal Bte1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHS", "evidence_id": "EV-PDB-8ZHS-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "8ZHS", "doi": "10.1016/j.chom.2025.01.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Mbp-Bte1 fusion protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACH"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZMS", "evidence_id": "EV-PDB-8ZMS-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8ZMS", "doi": "10.1038/s41422-024-00986-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZMS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Acetylcholine-bound VAChT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GPR15 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZQE", "evidence_id": "EV-PDB-8ZQE-5", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8ZQE", "doi": "10.1038/s41421-024-00698-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZQE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the GPR15L(C11)-bound GPR15 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ALT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BCG", "evidence_id": "EV-PDB-9BCG-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.898}, "provenance": {"deposit_id": "9BCG", "doi": "10.1021/acs.jmedchem.4c01188", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BCG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Myeloid cell leukemia-1 (Mcl-1) complexed with compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BDE", "evidence_id": "EV-PDB-9BDE-4", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.18}, "provenance": {"deposit_id": "9BDE", "doi": "10.1038/s41586-024-08223-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BDE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Middle Region of Apolipoprotein B 100 bound to Low Density Lipoprotein Receptor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["42H"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "mVenus,Maltose/maltodextrin-binding periplasmic protein,Protein spinster homolog 1,Designed ankyrin repeat protein (DARPin) (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BOI", "evidence_id": "EV-PDB-9BOI-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "9BOI", "doi": "10.1073/pnas.2409596121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BOI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human Spns1 in complex with LPC (18:1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Guillardia theta Fanzor1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CES", "evidence_id": "EV-PDB-9CES-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.28}, "provenance": {"deposit_id": "9CES", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Guillardia theta Fanzor (GtFz) State 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Guillardia theta Fanzor1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CET", "evidence_id": "EV-PDB-9CET-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9CET", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CET"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Guillardia theta Fanzor (GtFz) State 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Spizellomyces punctatus Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CEU", "evidence_id": "EV-PDB-9CEU-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "9CEU", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CEU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spizellomyces punctatus Fanzor (SpuFz) State 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Spizellomyces punctatus Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CEV", "evidence_id": "EV-PDB-9CEV-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "9CEV", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CEV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spizellomyces punctatus Fanzor (SpuFz) State 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Spizellomyces punctatus Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CEW", "evidence_id": "EV-PDB-9CEW-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88}, "provenance": {"deposit_id": "9CEW", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CEW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spizellomyces punctatus Fanzor (SpuFz) State 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Spizellomyces punctatus Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CEY", "evidence_id": "EV-PDB-9CEY-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "9CEY", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CEY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spizellomyces punctatus Fanzor (SpuFz) State 5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Spizellomyces punctatus Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CEZ", "evidence_id": "EV-PDB-9CEZ-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "9CEZ", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CEZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spizellomyces punctatus Fanzor (SpuFz) State 6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Parasitella parasitica Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CF0", "evidence_id": "EV-PDB-9CF0-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "9CF0", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CF0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Parasitella parasitica Fanzor (PpFz) State 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Parasitella parasitica Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CF1", "evidence_id": "EV-PDB-9CF1-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "9CF1", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CF1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Parasitella parasitica Fanzor (PpFz) State 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Parasitella parasitica Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CF2", "evidence_id": "EV-PDB-9CF2-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15}, "provenance": {"deposit_id": "9CF2", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CF2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Parasitella parasitica Fanzor (PpFz) State 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Parasitella parasitica Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CF3", "evidence_id": "EV-PDB-9CF3-4", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9CF3", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CF3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Parasitella parasitica Fanzor (PpFz) State 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD", "EDO", "NA", "PEG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CLC", "evidence_id": "EV-PDB-9CLC-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "9CLC", "doi": "10.1002/anie.202421000", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CLC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of maltose binding protein (Apo), mutant Trp10 to 4-Cyanotryptophan"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD", "EDO", "NA", "PEG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CLD", "evidence_id": "EV-PDB-9CLD-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "9CLD", "doi": "10.1002/anie.202421000", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CLD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of maltose binding protein (Apo)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9COO", "evidence_id": "EV-PDB-9COO-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "9COO", "doi": "10.1038/s41586-024-08223-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9COO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Nanobody 4 bound to Apolipoprotein B 100"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1A4L", "ADP", "CPS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 3 chimera (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DH3", "evidence_id": "EV-PDB-9DH3-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76}, "provenance": {"deposit_id": "9DH3", "doi": "10.1038/s44321-024-00181-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DH3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NLRP3 complex with Compound C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FGV", "evidence_id": "EV-PDB-9FGV-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "9FGV", "doi": "10.1038/s41589-025-01972-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FGV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of MBP homo-dimer assembled by homo Di-Gluebody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FKQ", "evidence_id": "EV-PDB-9FKQ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "9FKQ", "doi": "10.1038/s41589-025-01972-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FKQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of MBP homo-dimer assembled by homo Di-Gluebody - MBP local refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6UZ", "A1IHM", "A1IHN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pro-Macrobody 5,Maltose/maltodextrin-binding periplasmic protein (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FYQ", "evidence_id": "EV-PDB-9FYQ-3", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "9FYQ", "doi": "10.1038/s41467-025-59545-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FYQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of native SV2A in complex with TeNT-Hc, gangliosides and Pro-Macrobody 5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Bacterial antiviral defense protein Ec1ApeA from Escherichia coli strain NCTC8008 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HXN", "evidence_id": "EV-PDB-9HXN-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.23}, "provenance": {"deposit_id": "9HXN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HXN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Bacterial antiviral defense protein Ec1ApeA from Escherichia coli strain NCTC8008"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Bacterial antiviral defense protein Ec3ApeA from Escherichia coli strain KK-NP016 (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HXJ", "evidence_id": "EV-PDB-9HXJ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9HXJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HXJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Bacterial antiviral defense protein Ec3ApeA from Escherichia coli strain KK-NP016"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6UZ", "NAG", "UKX", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Pro-Macrobody 5,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FYR", "evidence_id": "EV-PDB-9FYR-3", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9FYR", "doi": "10.1038/s41467-025-59545-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FYR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of native SV2A in complex with TeNT-Hc, Pro-Macrobody 5 and Levetiracetam"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Spizellomyces punctatus Fanzor 1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CEX", "evidence_id": "EV-PDB-9CEX-4", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "9CEX", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CEX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spizellomyces punctatus Fanzor (SpuFz) State 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Guillardia theta Fanzor1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CER", "evidence_id": "EV-PDB-9CER-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.7}, "provenance": {"deposit_id": "9CER", "doi": "10.1016/j.cell.2024.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CER"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Guillardia theta Fanzor (GtFz) State 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltodextrin-binding protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BDT", "evidence_id": "EV-PDB-9BDT-4", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.4}, "provenance": {"deposit_id": "9BDT", "doi": "10.1038/s41586-024-08223-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BDT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Apolipoprotein B 100 bound to LDL receptor and legobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1LWL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZMR", "evidence_id": "EV-PDB-8ZMR-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8ZMR", "doi": "10.1038/s41422-024-00986-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZMR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Vesamicol-bound VAChT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GFP-MBP-solute carrier family 6 member 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XB4", "evidence_id": "EV-PDB-8XB4-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "8XB4", "doi": "10.1038/s41586-024-07810-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of apo state of the human Norepinephrine Transporter"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "YMN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GFP-MBP-solute carrier family 6 member 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XB3", "evidence_id": "EV-PDB-8XB3-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8XB3", "doi": "10.1038/s41586-024-07810-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XB3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "YNT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GFP-MBP-solute carrier family 6 member 2,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XB2", "evidence_id": "EV-PDB-8XB2-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8XB2", "doi": "10.1038/s41586-024-07810-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XB2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of radafaxine-bound state of the human Norepinephrine Transporter"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein fused to apoptosis regulator Bcl-2/Bcl-xL chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VXN", "evidence_id": "EV-PDB-8VXN-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.09}, "provenance": {"deposit_id": "8VXN", "doi": "10.1021/acs.analchem.4c04516", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VXN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Bcl-2/Bcl-xL Chimera Fused to Maltose-Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["F3Q", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein fused to apoptosis regulator Bcl-2/Bcl-xL chimera (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VWZ", "evidence_id": "EV-PDB-8VWZ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33}, "provenance": {"deposit_id": "8VWZ", "doi": "10.1021/acs.analchem.4c04516", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VWZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Bcl-2 (G101V Mutant)/Bcl-xL Chimera Fused to MBP in Complex with Inhibitor S55746"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -90.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Mucin-16 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VRS", "evidence_id": "EV-PDB-8VRS-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.47}, "provenance": {"deposit_id": "8VRS", "doi": "10.1186/s13048-024-01373-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VRS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mucin 16 peptide fused to MBP in complex with 4H11-scFv antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Transcription factor GATA-4 (chains T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VG1", "evidence_id": "EV-PDB-8VG1-8", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.48}, "provenance": {"deposit_id": "8VG1", "doi": "10.1016/j.molcel.2024.07.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VG1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of FoxA1 and GATA4 in complex with ALBN1 nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKU", "evidence_id": "EV-PDB-9SKU-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.06}, "provenance": {"deposit_id": "9SKU", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA in reducing conditions, hexamer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EF9", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Phosphoprotein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUM", "evidence_id": "EV-PDB-9VUM-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "9VUM", "doi": "10.1073/pnas.2522978123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Nipah virus RNA-dependent RNA polymerase complex bound to allosteric inhibitor ERDRP-0519"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EF9", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,RNA-directed RNA polymerase L (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUM", "evidence_id": "EV-PDB-9VUM-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "9VUM", "doi": "10.1073/pnas.2522978123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Nipah virus RNA-dependent RNA polymerase complex bound to allosteric inhibitor ERDRP-0519"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Probable G-protein coupled receptor 75,Maltose/maltodextrin-binding periplasmic protein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XQC", "evidence_id": "EV-PDB-9XQC-5", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9XQC", "doi": "10.1038/s41401-025-01720-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XQC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "A composite Cryo-EM structure of GPR75"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XKO", "evidence_id": "EV-PDB-9XKO-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "9XKO", "doi": "10.1038/s41467-026-71934-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XKO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "High-resolution cryo-EM structure of Maltose Binding Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Reverse transcriptase domain-containing protein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WY8", "evidence_id": "EV-PDB-9WY8-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "9WY8", "doi": "10.1016/j.bbrc.2025.152955", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WY8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the hexameric DRT6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Midnolin (chains f)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WBG", "evidence_id": "EV-PDB-9WBG-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.23}, "provenance": {"deposit_id": "9WBG", "doi": "10.1038/s41467-026-71002-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WBG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl and Catch domain resolved"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EMK", "CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GFP,Maltose/maltodextrin-binding periplasmic protein,Sodium- and chloride-dependent betaine transporter (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W98", "evidence_id": "EV-PDB-9W98-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "9W98", "doi": "10.1038/s41467-026-72924-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W98"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of ATPCA-bound state of the human betaine/GABA transporter 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EVN", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GFP,Maltose/maltodextrin-binding periplasmic protein,Sodium- and chloride-dependent betaine transporter (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W97", "evidence_id": "EV-PDB-9W97-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "9W97", "doi": "10.1038/s41467-026-72924-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W97"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BPDBA-bound state of the human betaine/GABA transporter 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W3K", "evidence_id": "EV-PDB-9W3K-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "9W3K", "doi": "10.1073/pnas.2534234123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W3K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "GPR151-Legobody complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Midnolin (chains f)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W39", "evidence_id": "EV-PDB-9W39-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65}, "provenance": {"deposit_id": "9W39", "doi": "10.1038/s41467-026-71002-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W39"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ITN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Soluble cytochrome b562,2-oxoglutarate receptor 1,Soluble cytochrome b562,2-oxoglutarate receptor 1,Soluble cytochrome b562,2-oxoglutarate receptor 1,Fusion protein,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VV6", "evidence_id": "EV-PDB-9VV6-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.62}, "provenance": {"deposit_id": "9VV6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VV6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of ITN bound OXGR1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AKG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Soluble cytochrome b562,2-oxoglutarate receptor 1,Soluble cytochrome b562,2-oxoglutarate receptor 1,Soluble cytochrome b562,2-oxoglutarate receptor 1,Fusion protein,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUS", "evidence_id": "EV-PDB-9VUS-5", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.37}, "provenance": {"deposit_id": "9VUS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of akg bound OXGR1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EF9", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,RNA-directed RNA polymerase L,Strep II and FLAG tag (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUL", "evidence_id": "EV-PDB-9VUL-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "9VUL", "doi": "10.1073/pnas.2522978123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase bound to allosteric inhibitor ERDRP-0519"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EF9", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Phosphoprotein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUL", "evidence_id": "EV-PDB-9VUL-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "9VUL", "doi": "10.1073/pnas.2522978123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase bound to allosteric inhibitor ERDRP-0519"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Leucine-rich repeat receptor protein kinase HPCA1,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VBV", "evidence_id": "EV-PDB-9VBV-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.61}, "provenance": {"deposit_id": "9VBV", "doi": "10.1038/s41467-026-72573-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a CARD1 ectodomain H197A/H199A/H222A mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CU", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Leucine-rich repeat receptor protein kinase HPCA1,Maltose/maltodextrin-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VBD", "evidence_id": "EV-PDB-9VBD-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "9VBD", "doi": "10.1038/s41467-026-72573-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VBD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CARD1 ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Bacteroides fragilis T6SS effector (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UU0", "evidence_id": "EV-PDB-9UU0-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "9UU0", "doi": "10.1073/pnas.2513207122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UU0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of Bacteroides fragilis T6SS effector BteO"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Egalitarian, isoform B (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UJY", "evidence_id": "EV-PDB-9UJY-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26}, "provenance": {"deposit_id": "9UJY", "doi": "10.1101/2025.08.03.668247", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UJY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of Egalitarian in complex with the K10 mRNA localization signal reveals a modular binding surface required for function"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Protein E6 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9U4D", "evidence_id": "EV-PDB-9U4D-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "9U4D", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9U4D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of UBE3A-E6-p53 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Nuclear autoantigen Sp-100 (chains A,AA,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,V,W,X,Y,Z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TNZ", "evidence_id": "EV-PDB-9TNZ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "9TNZ", "doi": "10.1038/s41556-026-01916-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TNZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SP100 CARD filament"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Zinc finger CCCH domain-containing protein 18 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9T3X", "evidence_id": "EV-PDB-9T3X-3", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "9T3X", "doi": "10.1093/nar/gkag088", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9T3X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of CPSF160-WDR33-ZC3H18"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKZ", "evidence_id": "EV-PDB-9SKZ-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.22}, "provenance": {"deposit_id": "9SKZ", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA C283A/C284A inactive mutant, dimer, state 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKY", "evidence_id": "EV-PDB-9SKY-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.18}, "provenance": {"deposit_id": "9SKY", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA C283A/C284A inactive mutant, dimer, state 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKX", "evidence_id": "EV-PDB-9SKX-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.08}, "provenance": {"deposit_id": "9SKX", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA C283A/C284A inactive mutant, hexamer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKW", "evidence_id": "EV-PDB-9SKW-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.27}, "provenance": {"deposit_id": "9SKW", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA in reducing conditions, dimer, minor state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKV", "evidence_id": "EV-PDB-9SKV-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.12}, "provenance": {"deposit_id": "9SKV", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA in reducing conditions, dimer, major state, inactive conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKT", "evidence_id": "EV-PDB-9SKT-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "9SKT", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA in oxidizing conditions, dimer, minor state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKS", "evidence_id": "EV-PDB-9SKS-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "9SKS", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA in oxidizing conditions, dimer, major state, active conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Carboxysome shell carbonic anhydrase (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SKR", "evidence_id": "EV-PDB-9SKR-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.13}, "provenance": {"deposit_id": "9SKR", "doi": "10.64898/2026.04.02.716132", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SKR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of H. neapolitanus CsoSCA in oxidizing conditions, hexamer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Triggering receptor expressed on myeloid cells 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PX5", "evidence_id": "EV-PDB-9PX5-1", "mappings": [{"confidence": "medium", "justification": "Linear alpha-1,4 maltodextrin bound (branched entity); maltose and maltodextrins close MBP.", "rule": "mbp-maltodextrin-closed", "state_id": "MBP-closed-maltose", "who": "rule:mbp-maltodextrin-closed"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9PX5", "doi": "10.1080/19420862.2025.2546554", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Fab 7268 in complex with MBP-TREM2 Ig domain fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Maltose/maltodextrin ABC transporter substrate-binding protein MalE (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PGN", "evidence_id": "EV-PDB-9PGN-1", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9PGN", "doi": "10.1002/pro.70425", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PGN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Two-conformer equilibrium of maltose-binding protein in the absence of ligand from residual dipolar coupling analysis"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BGC", "CA", "FUC", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Tissue factor,Maltose/maltodextrin-binding periplasmic protein (chains T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9P0X", "evidence_id": "EV-PDB-9P0X-4", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9P0X", "doi": "10.1182/blood.2025029430", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9P0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Nanodisc-embedded human TF/FVIIa/XK1 in complex with 10H10 Fab (nanodisc-subtracted)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,E3 ubiquitin-protein ligase UHRF1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LN6", "evidence_id": "EV-PDB-9LN6-2", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "9LN6", "doi": "10.1038/s41467-026-71519-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human NLRP14-UHRF1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 14 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LN6", "evidence_id": "EV-PDB-9LN6-1", "mappings": [{"confidence": "low", "justification": "Structure with no maltodextrin bound; MBP is open without sugar. Many entries are MBP fusions, so low.", "rule": "mbp-sugar-free-open", "state_id": "MBP-open-apo", "who": "rule:mbp-sugar-free-open"}], "molecule_id": "P0AEX9", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "9LN6", "doi": "10.1038/s41467-026-71519-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human NLRP14-UHRF1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 1H chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25237", "evidence_id": "EV-BMRB-25237", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25237", "doi": "10.13018/BMR25237", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25237"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=36181", "evidence_id": "EV-BMRB-36181", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr36181", "doi": "10.13018/BMR36181", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=36181"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of peptidyl-prolyl cis/trans isomerase domain of Trigger Factor in complex with MBP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=4354", "evidence_id": "EV-BMRB-4354", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr4354", "doi": "10.13018/BMR4354", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=4354"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution NMR Studies of a 42kDa Escherichia coli Maltose Binding Protein/ Beta-Cyclodextrin Complex: Chemical Shift Assignments and Analysis"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=4986", "evidence_id": "EV-BMRB-4986", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr4986", "doi": "10.13018/BMR4986", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=4986"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H,13C and 15N chemical shift assignment for the ligand-free state of maltodextrin-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=4987", "evidence_id": "EV-BMRB-4987", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr4987", "doi": "10.13018/BMR4987", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=4987"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H,13C and 15N chemical shift assignment for the maltotriose-bound state of 2H,13C,15N-labeled maltodextrin-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.5, "salt_mM": null, "temperature_c": 16.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=50089", "evidence_id": "EV-BMRB-50089", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr50089", "doi": "10.13018/BMR50089", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=50089"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "MBP in the solid state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=6807", "evidence_id": "EV-BMRB-6807", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr6807", "doi": "10.13018/BMR6807", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=6807"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H, 13C, and 15N chemical shift assignments for stereo-array isotope labelled (SAIL) maltodextrin-binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": null, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=7114", "evidence_id": "EV-BMRB-7114", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr7114", "doi": "10.13018/BMR7114", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=7114"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H, 13C, and 15N chemical shift assignment of Escherichia coli Maltose Binding Protein complexed with Beta-Cyclodextrin"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Na/KPO4 pH 7.0, 300 mM NaCl, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Survival motor neuron protein"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 11.3 nm.", "ph": 7.0, "salt_mM": null, "temperature_c": 4.0}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein with Survival motor neuron protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDL75/", "evidence_id": "EV-SASBDB-SASDL75", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "radius_of_gyration", "uncertainty": 0.373, "unit": "nm", "value": 3.909}, "provenance": {"deposit_id": "SASDL75", "doi": "10.1093/nar/gkab508", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDL75/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Na/KPO4 pH 7.0, 300 mM NaCl, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Survival motor neuron protein"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 17.9 nm.", "ph": 7.0, "salt_mM": null, "temperature_c": 4.0}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein with Survival motor neuron protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDL85/", "evidence_id": "EV-SASBDB-SASDL85", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "radius_of_gyration", "uncertainty": 0.599, "unit": "nm", "value": 5.577}, "provenance": {"deposit_id": "SASDL85", "doi": "10.1093/nar/gkab508", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDL85/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer."}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM Tris pH 7.5, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Uncharacterized protein Rv2242"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.45 nm.", "ph": null, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (D108A, K109A, E198A, N199A, K265A) with Uncharacterized protein Rv2242", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDU88/", "evidence_id": "EV-SASBDB-SASDU88", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "radius_of_gyration", "uncertainty": 0.835, "unit": "nm", "value": 2.8}, "provenance": {"deposit_id": "SASDU88", "doi": "10.1016/j.heliyon.2024.e40494", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDU88/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Domain architecture of the Mycobacterium tuberculosis MabR (Rv2242), a member of the PucR transcription factor family"}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM Tris pH 7.5, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Uncharacterized protein Rv2242"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 10.77 nm.", "ph": null, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein (D108A, K109A, E198A, N199A, K265A) with Uncharacterized protein Rv2242", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDU98/", "evidence_id": "EV-SASBDB-SASDU98", "mappings": [], "molecule_id": "P0AEX9", "observable": {"type": "radius_of_gyration", "uncertainty": 0.796, "unit": "nm", "value": 3.7}, "provenance": {"deposit_id": "SASDU98", "doi": "10.1016/j.heliyon.2024.e40494", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDU98/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Domain architecture of the Mycobacterium tuberculosis MabR (Rv2242), a member of the PucR transcription factor family"}
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{"components": [], "domains": [{"end": 111, "name": "SSB", "start": 6}], "gene": "ssb", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P0AGE0"}, "ligands": [], "modifications": [], "molecule_id": "P0AGE0", "molecule_type": "protein", "name": "Single-stranded DNA-binding protein", "organism": {"name": "Escherichia coli (strain K12)", "taxon_id": 83333}, "provenance": {"deposit_id": "P0AGE0", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0AGE0/entry"}, "record_type": "molecule", "sequence": "MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEVVVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSAPAAPSNEPPMDFDDDIPF", "sequence_length": 178}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -170.15}, "construct": {"description": "SINGLE-STRAND DNA-BINDING PROTEIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EYG", "evidence_id": "EV-PDB-1EYG-2", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1EYG", "doi": "10.1038/77943", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EYG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chymotryptic fragment of E. coli ssb bound to two 35-mer single strand DNAS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SINGLE-STRANDED DNA BINDING PROTEIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1KAW", "evidence_id": "EV-PDB-1KAW-1", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "1KAW", "doi": "10.1073/pnas.94.13.6652", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1KAW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "SINGLE STRANDED DNA BINDING PROTEIN MONOMER (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1QVC", "evidence_id": "EV-PDB-1QVC-1", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1QVC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1QVC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE ANALYSIS OF SINGLE STRANDED DNA BINDING PROTEIN (SSB) FROM E.COLI"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SSB-Ct Peptide (chains D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Z0U", "evidence_id": "EV-PDB-4Z0U-2", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "4Z0U", "doi": "10.1074/jbc.M115.655134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Z0U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNase HI/SSB-Ct complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Plasmid-derived single-stranded DNA-binding protein (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TG7", "evidence_id": "EV-PDB-8TG7-2", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.775}, "provenance": {"deposit_id": "8TG7", "doi": "10.1016/j.jmb.2024.168590", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TG7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Red beta C-terminal domain in complex with SSB C-terminal peptide, Form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TRP-MET-ASP-PHE-ASP-ASP-ASP-ILE-PRO-PHE (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TG8", "evidence_id": "EV-PDB-8TG8-2", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.576}, "provenance": {"deposit_id": "8TG8", "doi": "10.1016/j.jmb.2024.168590", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TG8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Red beta C-terminal domain in complex with SSB C-terminal peptide, Form 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Plasmid-derived single-stranded DNA-binding protein (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TGC", "evidence_id": "EV-PDB-8TGC-2", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.484}, "provenance": {"deposit_id": "8TGC", "doi": "10.1016/j.jmb.2024.168590", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TGC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Red beta C-terminal domain in complex with SSB C-terminal peptide, Form 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Single-stranded DNA-binding protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MZ9", "evidence_id": "EV-PDB-4MZ9-1", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "4MZ9", "doi": "10.1093/nar/gkt1238", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MZ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Revised structure of E. coli SSB"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SSB peptide (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3SXU", "evidence_id": "EV-PDB-3SXU-3", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "3SXU", "doi": "10.1038/emboj.2011.305", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3SXU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the E. coli SSB-DNA polymerase III interface"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SINGLE STRANDED DNA BINDING PROTEIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1EQQ", "evidence_id": "EV-PDB-1EQQ-2", "mappings": [], "molecule_id": "P0AGE0", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "1EQQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1EQQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SINGLE STRANDED DNA BINDING PROTEIN AND SSDNA COMPLEX"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Ubiquitin (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2K8B", "evidence_id": "EV-PDB-2K8B-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2K8B", "doi": "10.1074/jbc.M109.009126", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2K8B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of PLAA family ubiquitin binding domain (PFUC) cis isomer in complex with ubiquitin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Polyubiquitin-B (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PTF", "evidence_id": "EV-PDB-3PTF-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "3PTF", "doi": "10.1016/j.jmb.2011.03.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PTF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DDI", "evidence_id": "EV-PDB-4DDI-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.802}, "provenance": {"deposit_id": "4DDI", "doi": "10.1016/j.molcel.2012.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DDI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human OTUB1/UbcH5b~Ub/Ub"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains D,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DHJ", "evidence_id": "EV-PDB-4DHJ-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "4DHJ", "doi": "10.1038/nature10911", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DHJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin aldehyde (chains B,F,J,M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DHJ", "evidence_id": "EV-PDB-4DHJ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "4DHJ", "doi": "10.1038/nature10911", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DHJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.33, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4XOL", "evidence_id": "EV-PDB-4XOL-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "4XOL", "doi": "10.1038/ncomms9361", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4XOL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Observing the overall rocking motion of a protein in a crystal - Cubic Ubiquitin crystals."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "UBIQUITIN (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AF4", "evidence_id": "EV-PDB-5AF4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "5AF4", "doi": "10.1016/J.MOLCEL.2015.01.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AF4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Lys33-linked diUb"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "POLYUBIQUITIN-C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5AF5", "evidence_id": "EV-PDB-5AF5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.68}, "provenance": {"deposit_id": "5AF5", "doi": "10.1016/J.MOLCEL.2015.01.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5AF5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Lys33-linked triUb S.G. P 212121"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "tetra ubiquitin (chains A,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B83", "evidence_id": "EV-PDB-5B83-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.694}, "provenance": {"deposit_id": "5B83", "doi": "10.1038/ncomms12547", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B83"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Optineurin UBAN in complex with linear ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C7J", "evidence_id": "EV-PDB-5C7J-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "5C7J", "doi": "10.1016/j.molcel.2016.02.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C7J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5C7M", "evidence_id": "EV-PDB-5C7M-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "5C7M", "doi": "10.1016/j.molcel.2016.02.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5C7M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -160.15}, "construct": {"description": "Polyubiquitin-C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5H07", "evidence_id": "EV-PDB-5H07-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.586}, "provenance": {"deposit_id": "5H07", "doi": "10.1016/j.str.2016.11.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5H07"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "TNIP2-Ub complex, C2 form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "EDO", "PEG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NL4", "evidence_id": "EV-PDB-5NL4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.32}, "provenance": {"deposit_id": "5NL4", "doi": "10.1002/chem.201705543", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NL4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Zn1.3-E16V human ubiquitin (hUb) mutant adduct, from a solution 35 mM zinc acetate/1.3 mM E16V hUb"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NLF", "evidence_id": "EV-PDB-5NLF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "5NLF", "doi": "10.1002/chem.201705543", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NLF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Zn2.7-E16V human ubiquitin (hUb) mutant adduct, from a solution 100 mM zinc acetate/1.3 mM E16V hUb"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "EDO", "ETF", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NLI", "evidence_id": "EV-PDB-5NLI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "5NLI", "doi": "10.1002/chem.201705543", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NLI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Zn2-E16V human ubiquitin (hUb) mutant adduct, from a solution 35 mM zinc acetate/10% v/v TFE/1.3 mM E16V hUb"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 13.85}, "construct": {"description": "Polyubiquitin-C (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OE7", "evidence_id": "EV-PDB-5OE7-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "5OE7", "doi": "10.1016/j.chembiol.2017.08.006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of OTULIN bound to the Met1-linked diubiquitin activity probe"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.2, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Ubiquitin (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OHV", "evidence_id": "EV-PDB-5OHV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.801}, "provenance": {"deposit_id": "5OHV", "doi": "10.1016/j.molcel.2017.08.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OHV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "K33-specific affimer bound to K33 diUb"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin T66V/L67N mutant (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OXH", "evidence_id": "EV-PDB-5OXH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.601}, "provenance": {"deposit_id": "5OXH", "doi": "10.15252/embj.201797876", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OXH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "C-terminally retracted ubiquitin T66V/L67N mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin L67S mutant (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5OXI", "evidence_id": "EV-PDB-5OXI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.63}, "provenance": {"deposit_id": "5OXI", "doi": "10.15252/embj.201797876", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5OXI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "C-terminally retracted ubiquitin L67S mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin C variant (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5UDH", "evidence_id": "EV-PDB-5UDH-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "5UDH", "doi": "10.1016/j.str.2017.04.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5UDH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HHARI/ARIH1-UBCH7~Ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "ubiquitin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WQ4", "evidence_id": "EV-PDB-5WQ4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "5WQ4", "doi": "10.1080/15548627.2017.1391970", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WQ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of OPTN and linear diubiquitin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -80.15}, "construct": {"description": "Ubiquitin (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5ZQ3", "evidence_id": "EV-PDB-5ZQ3-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.182}, "provenance": {"deposit_id": "5ZQ3", "doi": "10.1016/j.cell.2018.04.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5ZQ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PDE-Ubiquitin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACY"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.3, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6A44", "evidence_id": "EV-PDB-6A44-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "6A44", "doi": "10.1021/jacs.8b07512", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6A44"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "R1EN(5-227)-ubiquitin fusion"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6NXK", "evidence_id": "EV-PDB-6NXK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "6NXK", "doi": "10.1073/pnas.1902889116", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6NXK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ubiquitin binding variants"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ubiquitin (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6OI4", "evidence_id": "EV-PDB-6OI4-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.76}, "provenance": {"deposit_id": "6OI4", "doi": "10.1074/jbc.AC119.008881", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6OI4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RPN13 (19-132)-RPN2 (940-952) pY950-Ub complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "NI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ubiquitin (chains B,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5E6J", "evidence_id": "EV-PDB-5E6J-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "5E6J", "doi": "10.1016/j.molcel.2016.04.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5E6J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ubiquitin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4ZQS", "evidence_id": "EV-PDB-4ZQS-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.804}, "provenance": {"deposit_id": "4ZQS", "doi": "10.1107/S2059798316001510", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4ZQS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "New compact conformation of linear Ub2 structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "PO4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MSQ", "evidence_id": "EV-PDB-4MSQ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.952}, "provenance": {"deposit_id": "4MSQ", "doi": "10.1021/bi5003162", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MSQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 catalytic domain bound to ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["U94"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4MDK", "evidence_id": "EV-PDB-4MDK-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6095}, "provenance": {"deposit_id": "4MDK", "doi": "10.1038/nchembio.1412", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4MDK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cdc34-ubiquitin-CC0651 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BR", "CL", "EDO", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Polyubiquitin-C (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6QML", "evidence_id": "EV-PDB-6QML-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "6QML", "doi": "10.1016/j.chembiol.2020.11.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6QML"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "UCHL3 in complex with synthetic, K27-linked diubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains B,D,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6RYA", "evidence_id": "EV-PDB-6RYA-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.21}, "provenance": {"deposit_id": "6RYA", "doi": "10.1016/j.molcel.2019.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6RYA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Dup1 mutant H67A:Ubiquitin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPD", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains D,F,J,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6S53", "evidence_id": "EV-PDB-6S53-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "6S53", "doi": "10.1038/s41467-019-12388-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6S53"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6TTU", "evidence_id": "EV-PDB-6TTU-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "6TTU", "doi": "10.1038/s41586-020-2000-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6TTU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SAH", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains F,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6WKR", "evidence_id": "EV-PDB-6WKR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "6WKR", "doi": "10.1126/science.abc3393", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6WKR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6WTG", "evidence_id": "EV-PDB-6WTG-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.63}, "provenance": {"deposit_id": "6WTG", "doi": "10.1021/acs.biochem.0c00760", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6WTG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SdeA DUB Domain in complex with Ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GVE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YPT", "evidence_id": "EV-PDB-6YPT-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.663}, "provenance": {"deposit_id": "6YPT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YPT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray structure of Turnip Yellow Mosaic Virus PRO/DUB in complex with Ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z7V", "evidence_id": "EV-PDB-6Z7V-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "6Z7V", "doi": "10.1016/j.molcel.2021.08.024", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Mindy2 (C266A) in complex with Lys48 linked di-ubiquitin (K48-Ub2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B5M", "evidence_id": "EV-PDB-7B5M-6", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.91}, "provenance": {"deposit_id": "7B5M", "doi": "10.1038/s41586-021-03197-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B5M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BBD", "evidence_id": "EV-PDB-7BBD-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "7BBD", "doi": "10.1038/s41467-021-21443-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BBD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains C,F,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BBF", "evidence_id": "EV-PDB-7BBF-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.54}, "provenance": {"deposit_id": "7BBF", "doi": "10.1038/s41467-021-21443-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BBF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R71", "evidence_id": "EV-PDB-7R71-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7R71", "doi": "10.1038/s41467-022-28782-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R71"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the UbArk2C-UbcH5b~Ub complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains C,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TV4", "evidence_id": "EV-PDB-7TV4-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7TV4", "doi": "10.1038/s41598-022-16193-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TV4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UV5", "evidence_id": "EV-PDB-7UV5-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "7UV5", "doi": "10.1038/s41467-023-38031-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UV5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of Papain-Like Protease of SARS CoV-2, C111S/D286N mutant, in complex with a Lys48-linked di-ubiquitin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8E7O", "evidence_id": "EV-PDB-8E7O-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8E7O", "doi": "10.1038/s41467-023-43025-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8E7O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF LYS48-LINKED TETRAUBIQUITIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8E7O", "evidence_id": "EV-PDB-8E7O-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8E7O", "doi": "10.1038/s41467-023-43025-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8E7O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF LYS48-LINKED TETRAUBIQUITIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EAZ", "evidence_id": "EV-PDB-8EAZ-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "8EAZ", "doi": "10.1038/s41467-023-35871-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EAZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HOIL-1/E2-Ub/Ub transthiolation complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EB0", "evidence_id": "EV-PDB-8EB0-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "8EB0", "doi": "10.1038/s41467-023-35871-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RNF216/E2-Ub/Ub transthiolation complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZTO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FTQ", "evidence_id": "EV-PDB-8FTQ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8FTQ", "doi": "10.1038/s41467-024-46644-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FTQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-B (chains u,v,w)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JRT", "evidence_id": "EV-PDB-8JRT-26", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8JRT", "doi": "10.1038/s41467-025-64719-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JRT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human 26S proteasomal RP subcomplex (Ea state) bound to K11/K48-branched ubiquitin (Ub) chain composed of three Ub."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-B (chains u,v,w,x)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JTI", "evidence_id": "EV-PDB-8JTI-26", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8JTI", "doi": "10.1038/s41467-025-64719-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human 26S RP (Eb state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "AR6"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-B (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K6E", "evidence_id": "EV-PDB-8K6E-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74}, "provenance": {"deposit_id": "8K6E", "doi": "10.1038/s41589-025-01945-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K6E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LnaB-Actin-PRUb ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AR6", "ATP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K6F", "evidence_id": "EV-PDB-8K6F-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "8K6F", "doi": "10.1038/s41589-025-01945-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K6F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LnaB-Actin-PRUb ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AR6", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ubiquitin (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K6I", "evidence_id": "EV-PDB-8K6I-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "8K6I", "doi": "10.1038/s41589-025-01945-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K6I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LnaB-Actin-PRUb ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "AR6"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K6R", "evidence_id": "EV-PDB-8K6R-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "8K6R", "doi": "10.1038/s41589-025-01945-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K6R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LnaB-Actin-PRUb ternary complex in the presence of AMPPNP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "AR6"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K6V", "evidence_id": "EV-PDB-8K6V-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8K6V", "doi": "10.1038/s41589-025-01945-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K6V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LnaB-Actin-PRUb ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains Fa)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OFF", "evidence_id": "EV-PDB-8OFF-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8OFF", "doi": "10.1093/nar/gkad793", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OFF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes (Map1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains u)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PJN", "evidence_id": "EV-PDB-8PJN-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8PJN", "doi": "10.1016/j.molcel.2023.11.027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PJN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PMQ", "evidence_id": "EV-PDB-8PMQ-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "8PMQ", "doi": "10.1016/j.molcel.2023.11.027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PMQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SY8", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PQL", "evidence_id": "EV-PDB-8PQL-5", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76}, "provenance": {"deposit_id": "8PQL", "doi": "10.1038/s41594-023-01206-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PQL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SY8", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C,Nucleotide exchange factor SIL1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PQL", "evidence_id": "EV-PDB-8PQL-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76}, "provenance": {"deposit_id": "8PQL", "doi": "10.1038/s41594-023-01206-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PQL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin carboxyl-terminal hydrolase MINDY (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q06", "evidence_id": "EV-PDB-8Q06-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8Q06", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q06"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "EF-hand of MINDY3 Deubiquitylase in Complex with UBL of RAD23A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["U9O", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q7R", "evidence_id": "EV-PDB-8Q7R-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.71}, "provenance": {"deposit_id": "8Q7R", "doi": "10.1016/j.molcel.2024.01.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q7R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["759", "SY8", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8R5H", "evidence_id": "EV-PDB-8R5H-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "8R5H", "doi": "10.1016/j.molcel.2024.01.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8R5H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["759", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-B (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RX0", "evidence_id": "EV-PDB-8RX0-9", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8RX0", "doi": "10.1126/sciadv.ado6492", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RX0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "(NEDD8)-CRL2VHL-MZ1-Brd4BD2-Ub(G76S, K48C)-UBE2R1(C93K, S138C, C191S, C223S)-Ub"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AYE", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SSI", "evidence_id": "EV-PDB-8SSI-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8SSI", "doi": "10.1016/j.chom.2024.04.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SSI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Burkholderia pseudomallei deubiquitinase TssM in complex with ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AYE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ST8", "evidence_id": "EV-PDB-8ST8-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "8ST8", "doi": "10.1016/j.molcel.2023.11.017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ST8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of E3 ligase SopA bound to ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AYE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ST9", "evidence_id": "EV-PDB-8ST9-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8ST9", "doi": "10.1016/j.molcel.2023.11.017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ST9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of E3 ligase NleL bound to ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SVF", "evidence_id": "EV-PDB-8SVF-9", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8SVF", "doi": "10.1126/sciadv.adg9832", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SVF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BAP1/ASXL1 bound to the H2AK119Ub Nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "LI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Di-Ubiquitin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T48", "evidence_id": "EV-PDB-8T48-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "8T48", "doi": "10.1016/j.immuni.2024.04.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T48"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The N4BP1 CUE-like domain in complex with linear di-Ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8U5H", "evidence_id": "EV-PDB-8U5H-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.23}, "provenance": {"deposit_id": "8U5H", "doi": "10.1038/s41467-024-50526-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8U5H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human DNMT3A UDR bound to H2AK119ub1-modified nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains i,j)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZDC", "evidence_id": "EV-PDB-8ZDC-37", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8ZDC", "doi": "10.1016/j.molcel.2025.01.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZDC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains i,j)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZDD", "evidence_id": "EV-PDB-8ZDD-36", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8ZDD", "doi": "10.1016/j.molcel.2025.01.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZDD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3 (without NOB1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains A,B)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZZ4", "evidence_id": "EV-PDB-8ZZ4-1", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8ZZ4", "doi": "10.1021/acs.biochem.7b00817", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZZ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Structure of K63-linked Diubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains B)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A1L", "evidence_id": "EV-PDB-9A1L-2", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A1L", "doi": "10.1038/s41420-024-01913-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A1L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "N4BP1 CUE domain in complex with ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D1I", "evidence_id": "EV-PDB-9D1I-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9D1I", "doi": "10.1038/s41467-024-54126-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D1I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Ubiquitin bound to KLHDC3-EloB/C"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin-C (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D8P", "evidence_id": "EV-PDB-9D8P-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9D8P", "doi": "10.1038/s41467-024-54126-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D8P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Focused map of Cryo-EM structure of Ubiquitin C-degron bound to KLHDC10-EloB/C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DBY", "evidence_id": "EV-PDB-9DBY-11", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9DBY", "doi": "10.1038/s41586-024-08183-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ncPRC1RYBP bound to singly modified H2AK119Ub nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DDE", "evidence_id": "EV-PDB-9DDE-10", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9DDE", "doi": "10.1038/s41586-024-08183-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DDE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ncPRC1RYBP bound to H2AK119Ub/H1.4 chromatosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DG3", "evidence_id": "EV-PDB-9DG3-9", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "9DG3", "doi": "10.1038/s41586-024-08183-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ncPRC1RYBP Delta-linker mutant bound to singly modified H2AK119Ub nucleosome"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1A4Y", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DI2", "evidence_id": "EV-PDB-9DI2-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9DI2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DI2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the USP1-UAF1-Ubiquitin-VS complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains U,V,W,X)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DNS", "evidence_id": "EV-PDB-9DNS-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9DNS", "doi": "10.1016/j.celrep.2025.115688", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DNS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Tom1-UBE2D2-ubiquitin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "SO4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EGV", "evidence_id": "EV-PDB-9EGV-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9EGV", "doi": "10.26508/lsa.202503243", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EGV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HOIL-1 RING2 domain bound to ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "SO4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EGW", "evidence_id": "EV-PDB-9EGW-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.78}, "provenance": {"deposit_id": "9EGW", "doi": "10.26508/lsa.202503243", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HOIL-1 RING2 domain bound to ubiquitin-maltose (maltose not modelled)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1A4Y", "A1BHF", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EBS", "evidence_id": "EV-PDB-9EBS-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9EBS", "doi": "10.1158/1535-7163.MCT-24-0515", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EBS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of USP1-UAF1-Ubiquitin in complex with TNG348"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8B3I", "evidence_id": "EV-PDB-8B3I-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8B3I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8B3I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CRL4CSA-E2-Ub (state 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PE8", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AMS", "evidence_id": "EV-PDB-8AMS-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "8AMS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AMS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C,Ub-fused CBLock peptide (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ERZ", "evidence_id": "EV-PDB-9ERZ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "9ERZ", "doi": "10.1016/j.ymthe.2025.04.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ERZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of CBL-TKBD bound to Ubiquitin-fused CBLock peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IB8", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FCI", "evidence_id": "EV-PDB-9FCI-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9FCI", "doi": "10.1021/acs.jmedchem.4c01184", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FCI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "USP1 bound to KSQ-4279 and ubiquitin conjugated to FANCD2 (focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["JDA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FCJ", "evidence_id": "EV-PDB-9FCJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9FCJ", "doi": "10.1021/acs.jmedchem.4c01184", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FCJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (ordered subset, focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IDH"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains A,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FJ3", "evidence_id": "EV-PDB-9FJ3-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "9FJ3", "doi": "10.1039/d4sc04204b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FJ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of ubiquitin bound of coiled-coil UIM form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IDH"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FJ4", "evidence_id": "EV-PDB-9FJ4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.54}, "provenance": {"deposit_id": "9FJ4", "doi": "10.1039/d4sc04204b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FJ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of ubiquitin bound to coiled coil-UIM form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SY8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9GKN", "evidence_id": "EV-PDB-9GKN-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9GKN", "doi": "10.1038/s41594-025-01561-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9GKN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HECT E3 TRIP12 forming K29-linked Ubiquitin chains"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SY8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9GKN", "evidence_id": "EV-PDB-9GKN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9GKN", "doi": "10.1038/s41594-025-01561-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9GKN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HECT E3 TRIP12 forming K29-linked Ubiquitin chains"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-B (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HNW", "evidence_id": "EV-PDB-9HNW-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "9HNW", "doi": "10.1038/s41467-025-61768-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HNW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "USP1-UAF1 bound to Lys63-linked diubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-B (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HNW", "evidence_id": "EV-PDB-9HNW-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "9HNW", "doi": "10.1038/s41467-025-61768-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HNW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "USP1-UAF1 bound to Lys63-linked diubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SRE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Ubiquitin (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IJU", "evidence_id": "EV-PDB-9IJU-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.46}, "provenance": {"deposit_id": "9IJU", "doi": "10.1021/acs.jmedchem.5c00032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IJU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Sertraline enhances the deubiquitinase activity of USP7 by binding to its switching loop region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SAM", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ISZ", "evidence_id": "EV-PDB-9ISZ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9ISZ", "doi": "10.1126/sciadv.adu1864", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ISZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Clr4 catalyzing K14-ubiquitinated histone H3 K9 methylation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin K29C (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KEN", "evidence_id": "EV-PDB-9KEN-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "9KEN", "doi": "10.1038/s41467-025-59569-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KEN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of TRIP12 in complex with K29/48 branched-triUb"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KEN", "evidence_id": "EV-PDB-9KEN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "9KEN", "doi": "10.1038/s41467-025-59569-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KEN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of TRIP12 in complex with K29/48 branched-triUb"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KHS", "evidence_id": "EV-PDB-9KHS-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.31}, "provenance": {"deposit_id": "9KHS", "doi": "10.1038/s41589-025-01985-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked diUb (monomeric conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KHS", "evidence_id": "EV-PDB-9KHS-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.31}, "provenance": {"deposit_id": "9KHS", "doi": "10.1038/s41589-025-01985-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked diUb (monomeric conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KHS", "evidence_id": "EV-PDB-9KHS-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.31}, "provenance": {"deposit_id": "9KHS", "doi": "10.1038/s41589-025-01985-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked diUb (monomeric conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9M7O", "evidence_id": "EV-PDB-9M7O-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.14}, "provenance": {"deposit_id": "9M7O", "doi": "10.1038/s41589-025-01985-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9M7O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Ufd2/Ubc4-ub complex with K29triUb(monomeric conformation)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PLQ", "evidence_id": "EV-PDB-9PLQ-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "9PLQ", "doi": "10.1016/j.molcel.2026.08.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PLQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "HUWE1(CS)-Ubiquitin bound to the HECT domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin-40S ribosomal protein S27a (chains F,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q8Y", "evidence_id": "EV-PDB-9Q8Y-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.63}, "provenance": {"deposit_id": "9Q8Y", "doi": "10.26508/lsa.202503394", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q8Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of RNF38 RING with linchpin mutant R454Y in complex with Ubch5B-Ub"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QGG", "evidence_id": "EV-PDB-9QGG-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.58}, "provenance": {"deposit_id": "9QGG", "doi": "10.1038/s41594-025-01717-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QGG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Consensus structure of dUBA1-UbDha-dBIRC6 trapped ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP", "IHP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QIA", "evidence_id": "EV-PDB-9QIA-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.38}, "provenance": {"deposit_id": "9QIA", "doi": "10.1038/s41594-025-01717-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QIA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of UBA6-UbDha-BIRC6 trapped ternary complex (cluster 2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains K,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMN", "evidence_id": "EV-PDB-9SMN-6", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9SMN", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-polyUbATA - open form StateC StateP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains L,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMN", "evidence_id": "EV-PDB-9SMN-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9SMN", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-polyUbATA - open form StateC StateP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains S,T,U,V)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMN", "evidence_id": "EV-PDB-9SMN-8", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9SMN", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-polyUbATA - open form StateC StateP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains K,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMP", "evidence_id": "EV-PDB-9SMP-6", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9SMP", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-polyUbATA - open form double State P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMP", "evidence_id": "EV-PDB-9SMP-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9SMP", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-polyUbATA - open form double State P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMP", "evidence_id": "EV-PDB-9SMP-8", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9SMP", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-polyUbATA - open form double State P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains S,T,U,V)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMP", "evidence_id": "EV-PDB-9SMP-9", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9SMP", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-polyUbATA - open form double State P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains S)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SMS", "evidence_id": "EV-PDB-9SMS-5", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9SMS", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SMS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex: Ubiquitin bound to BRE at the wrist site (focused 3D class)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1JPL", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains L,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SNA", "evidence_id": "EV-PDB-9SNA-6", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9SNA", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SNA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-diUbATA - open form StateC StateP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1JPL", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains K,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SNA", "evidence_id": "EV-PDB-9SNA-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9SNA", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SNA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-diUbATA - open form StateC StateP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1JPL", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SNA", "evidence_id": "EV-PDB-9SNA-8", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9SNA", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SNA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-diUbATA - open form StateC StateP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SO9", "evidence_id": "EV-PDB-9SO9-6", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9SO9", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-oligoUbATA - closed form StateC*"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SO9", "evidence_id": "EV-PDB-9SO9-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9SO9", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-oligoUbATA - closed form StateC*"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SO9", "evidence_id": "EV-PDB-9SO9-8", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9SO9", "doi": "10.1038/s41467-026-75797-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BRCA1-A complex bound to K63-oligoUbATA - closed form StateC*"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SQV", "evidence_id": "EV-PDB-9SQV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.21}, "provenance": {"deposit_id": "9SQV", "doi": "10.1038/s41467-026-75795-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the ARISCdC(E33A):K63-Ub4 complex (Composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SQW", "evidence_id": "EV-PDB-9SQW-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9SQW", "doi": "10.1038/s41467-026-75795-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SQW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the ARISCdC(E33A):K63-Ub7 complex (Composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SQY", "evidence_id": "EV-PDB-9SQY-5", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "9SQY", "doi": "10.1038/s41467-026-75795-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SQY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the ARISC(E33A)-RAP80:K63-Ub7 complex (Composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["COA", "GTP", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin-60S ribosomal protein L40 (chains LD)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SYR", "evidence_id": "EV-PDB-9SYR-72", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "9SYR", "doi": "10.1126/sciadv.aeb1017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SYR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FE", "SY8", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9T7V", "evidence_id": "EV-PDB-9T7V-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9T7V", "doi": "10.1038/s41467-026-72524-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9T7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of LRRC58-EloB/C-CDO1 in complex with NEDD8-CUL5-RBX2-ARIH2-Ub"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EQF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Ubiquitin (chains B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UV6", "evidence_id": "EV-PDB-9UV6-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9UV6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UV6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Encounter complex structure of E2N and Ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EY9", "GOL", "NI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains F,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WYW", "evidence_id": "EV-PDB-9WYW-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "9WYW", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WYW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of K27-linked di-ubiquitin in complex with synthetic antigen binding fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YEA", "evidence_id": "EV-PDB-9YEA-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "9YEA", "doi": "10.1016/j.bbrc.2025.152873", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the isopeptide bond-linked UbcH5b~Ubiquitin conjugate complex for an M1K/C85K UbcH5b mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP", "IHP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YLF", "evidence_id": "EV-PDB-9YLF-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "9YLF", "doi": "10.1038/s41467-026-69882-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YLF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of single-loaded human UBA6-UBE2Z/Ub(a) adenylate complex."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AYE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ubiquitin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R85", "evidence_id": "EV-PDB-9R85-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "9R85", "doi": "10.1038/s41467-026-69520-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R85"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the E3 ligase HECTD3 conjugated to ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP", "IHP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QH5", "evidence_id": "EV-PDB-9QH5-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09}, "provenance": {"deposit_id": "9QH5", "doi": "10.1038/s41594-025-01717-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QH5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Consensus structure of UBA6-UbDha-BIRC6 trapped ternary complex (doubly loaded)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "IHP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QGW", "evidence_id": "EV-PDB-9QGW-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.62}, "provenance": {"deposit_id": "9QGW", "doi": "10.1038/s41594-025-01717-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Consensus structure of UBA6-UbDha-BIRC6 trapped ternary complex (singly loaded)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QGR", "evidence_id": "EV-PDB-9QGR-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9QGR", "doi": "10.1038/s41594-025-01717-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QGR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of dUBA1-UbDha-dBIRC6 trapped ternary complex (Cluster 4)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QGI", "evidence_id": "EV-PDB-9QGI-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "9QGI", "doi": "10.1038/s41594-025-01717-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QGI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of dUBA1-UbDha-dBIRC6 trapped ternary complex (Cluster 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OVX", "evidence_id": "EV-PDB-9OVX-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "9OVX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF UBIQUITIN K27M MUTANT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Polyubiquitin-C (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9O4M", "evidence_id": "EV-PDB-9O4M-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9O4M", "doi": "10.1002/cbic.202500318", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9O4M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Ubiquitin Carboxy Terminal Hydrolase L1 Q209C mutant covalently crosslinked to ubiquitin genetically encoded with N6-(6-bromohexanoyl)-L-lysine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AMP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MC4", "evidence_id": "EV-PDB-9MC4-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "9MC4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C (chains D,d)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KHT", "evidence_id": "EV-PDB-9KHT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.85}, "provenance": {"deposit_id": "9KHT", "doi": "10.1038/s41589-025-01985-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KHT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked triUb (dimeric conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["XB7"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ubiquitin (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IML", "evidence_id": "EV-PDB-9IML-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "9IML", "doi": "10.1021/acs.jmedchem.5c00032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IML"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Sertraline enhances the deubiquitinase activity of USP7 by binding to its switching loop region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SY8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-B (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9GKM", "evidence_id": "EV-PDB-9GKM-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure containing ubiquitin; free and bound ubiquitin keep the native fold unless the title says otherwise.", "rule": "ub-structures-folded", "state_id": "Ub-folded", "who": "rule:ub-structures-folded"}], "molecule_id": "P0CG48", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.69}, "provenance": {"deposit_id": "9GKM", "doi": "10.1038/s41594-025-01561-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9GKM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HECT E3 TRIP12 forming K29/K48-branched Ubiquitin chains"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 5.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5387", "evidence_id": "EV-BMRB-5387", "mappings": [{"confidence": "low", "justification": "NMR shift or relaxation entry for ubiquitin under native conditions.", "rule": "ub-nmr-folded", "state_id": "Ub-folded", "who": "rule:ub-nmr-folded"}], "molecule_id": "P0CG48", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5387", "doi": "10.13018/BMR5387", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5387"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Complete 1H, 13C, and 15N chemical shifts for human recombinant ubiquitin in reverse micelles"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.6, "salt_mM": null, "temperature_c": 18.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=6457", "evidence_id": "EV-BMRB-6457", "mappings": [{"confidence": "low", "justification": "NMR shift or relaxation entry for ubiquitin under native conditions.", "rule": "ub-nmr-folded", "state_id": "Ub-folded", "who": "rule:ub-nmr-folded"}], "molecule_id": "P0CG48", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr6457", "doi": "10.13018/BMR6457", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=6457"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Validation of Protein Structure from Anisotropic Carbonyl Chemical Shifts in a Dilute Liquid Crystalline Phase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": null, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts, order parameters, T1 relaxation values", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=6466", "evidence_id": "EV-BMRB-6466", "mappings": [{"confidence": "low", "justification": "NMR shift or relaxation entry for ubiquitin under native conditions.", "rule": "ub-nmr-folded", "state_id": "Ub-folded", "who": "rule:ub-nmr-folded"}], "molecule_id": "P0CG48", "observable": {"type": "relaxation_rate", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr6466", "doi": "10.13018/BMR6466", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=6466"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_dynamics", "title": "Internal Dynamics of Human Ubiquitin Revealed by 13C-Relaxation Studies of Randomly Fractionally Labeled Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.7, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: heteronuclear NOE values, T1 relaxation values, T2 relaxation values, order parameters", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=6470", "evidence_id": "EV-BMRB-6470", "mappings": [{"confidence": "low", "justification": "NMR shift or relaxation entry for ubiquitin under native conditions.", "rule": "ub-nmr-folded", "state_id": "Ub-folded", "who": "rule:ub-nmr-folded"}], "molecule_id": "P0CG48", "observable": {"type": "relaxation_rate", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr6470", "doi": "10.13018/BMR6470", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=6470"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_dynamics", "title": "Rotational Diffusion Anisotropy of Human Ubiquitin from 15N NMR Relaxation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.7, "salt_mM": null, "temperature_c": 49.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=68", "evidence_id": "EV-BMRB-68", "mappings": [{"confidence": "low", "justification": "NMR shift or relaxation entry for ubiquitin under native conditions.", "rule": "ub-nmr-folded", "state_id": "Ub-folded", "who": "rule:ub-nmr-folded"}], "molecule_id": "P0CG48", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr68", "doi": "10.13018/BMR68", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=68"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Sequential 1H NMR Assignments and Secondary Structure Identification of Human Ubiquitin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 4.0, "salt_mM": null, "temperature_c": -5.15}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=7111", "evidence_id": "EV-BMRB-7111", "mappings": [{"confidence": "low", "justification": "NMR shift or relaxation entry for ubiquitin under native conditions.", "rule": "ub-nmr-folded", "state_id": "Ub-folded", "who": "rule:ub-nmr-folded"}], "molecule_id": "P0CG48", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr7111", "doi": "10.13018/BMR7111", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=7111"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Chemical shift assignment of multicrystalline ubiquitin using solid state MAS NMR spectroscopy"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES 200 mM NaCl 0.01 mM ZnSO4 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: E3 ubiquitin-protein ligase RNF8", "partner: Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 18.85 nm.", "ph": 6.8, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C with E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDBR3/", "evidence_id": "EV-SASBDB-SASDBR3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 4.45}, "provenance": {"deposit_id": "SASDBR3", "doi": "10.1074/jbc.M116.715698", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDBR3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES 200 mM NaCl 0.01 mM ZnSO4 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: E3 ubiquitin-protein ligase RNF8", "partner: Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A)", "partner: Ubiquitin-conjugating enzyme E2 variant 2"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 23.8 nm.", "ph": 6.8, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C with E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A), Ubiquitin-conjugating enzyme E2 variant 2", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDBS3/", "evidence_id": "EV-SASBDB-SASDBS3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.21, "unit": "nm", "value": 5.38}, "provenance": {"deposit_id": "SASDBS3", "doi": "10.1074/jbc.M116.715698", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDBS3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES 200 mM NaCl 0.01 mM ZnSO4 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: E3 ubiquitin-protein ligase RNF8 mutant (L451D)", "partner: Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 18.94 nm.", "ph": 6.8, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C with Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A), E3 ubiquitin-protein ligase RNF8 mutant (L451D)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDBT3/", "evidence_id": "EV-SASBDB-SASDBT3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 4.28}, "provenance": {"deposit_id": "SASDBT3", "doi": "10.1074/jbc.M116.715698", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDBT3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES 200 mM NaCl 0.01 mM ZnSO4 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: E3 ubiquitin-protein ligase RNF8 mutant (L451D)", "partner: Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A)", "partner: Ubiquitin-conjugating enzyme E2 variant 2"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 23.8 nm.", "ph": 6.8, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Polyubiquitin-C with Ubiquitin-conjugating enzyme E2 N double mutant (C87K, K92A), Ubiquitin-conjugating enzyme E2 variant 2, E3 ubiquitin-protein ligase RNF8 mutant (L451D)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDBU3/", "evidence_id": "EV-SASBDB-SASDBU3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 5.19}, "provenance": {"deposit_id": "SASDBU3", "doi": "10.1074/jbc.M116.715698", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDBU3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment."}
{"conditions": {"applied_force_pn": null, "buffer": "20mM HEPES, 150mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 7 nm.", "ph": 7.4, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "Polyubiquitin-C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDCG7/", "evidence_id": "EV-SASBDB-SASDCG7", "mappings": [{"confidence": "low", "justification": "SAXS of ubiquitin alone under native conditions; samples with partners are excluded.", "rule": "ub-saxs-folded", "state_id": "Ub-folded", "who": "rule:ub-saxs-folded"}], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.15, "unit": "nm", "value": 2.0}, "provenance": {"deposit_id": "SASDCG7", "doi": "10.1021/acs.biochem.7b00817", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDCG7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Characterizing Protein Dynamics with Integrative Use of Bulk and Single-Molecule Techniques."}
{"conditions": {"applied_force_pn": null, "buffer": "100mM NaCl, 10mM sodium acetate", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.5 nm.", "ph": 6.0, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "Polyubiquitin-C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDCL6/", "evidence_id": "EV-SASBDB-SASDCL6", "mappings": [{"confidence": "low", "justification": "SAXS of ubiquitin alone under native conditions; samples with partners are excluded.", "rule": "ub-saxs-folded", "state_id": "Ub-folded", "who": "rule:ub-saxs-folded"}], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.01, "unit": "nm", "value": 2.084}, "provenance": {"deposit_id": "SASDCL6", "doi": "10.7554/eLife.05767", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDCL6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM NaCl, 5 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Ubiquitin carboxyl-terminal hydrolase MINDY-2"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.8 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Polyubiquitin-C with Ubiquitin carboxyl-terminal hydrolase MINDY-2", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDJA3/", "evidence_id": "EV-SASBDB-SASDJA3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.05, "unit": "nm", "value": 2.31}, "provenance": {"deposit_id": "SASDJA3", "doi": "10.1016/j.molcel.2021.08.024", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDJA3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM NaCl, 5 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Ubiquitin carboxyl-terminal hydrolase C266A mutant"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Polyubiquitin-C with Ubiquitin carboxyl-terminal hydrolase C266A mutant", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDJB3/", "evidence_id": "EV-SASBDB-SASDJB3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.01, "unit": "nm", "value": 2.51}, "provenance": {"deposit_id": "SASDJB3", "doi": "10.1016/j.molcel.2021.08.024", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDJB3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM NaCl, 5 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Ubiquitin carboxyl-terminal hydrolase C266A mutant"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.77 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Polyubiquitin-C with Ubiquitin carboxyl-terminal hydrolase C266A mutant", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDJC3/", "evidence_id": "EV-SASBDB-SASDJC3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.01, "unit": "nm", "value": 2.83}, "provenance": {"deposit_id": "SASDJC3", "doi": "10.1016/j.molcel.2021.08.024", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDJC3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM NaCl, 5 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Ubiquitin carboxyl-terminal hydrolase C266A mutant"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.2 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Polyubiquitin-C with Ubiquitin carboxyl-terminal hydrolase C266A mutant", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDJD3/", "evidence_id": "EV-SASBDB-SASDJD3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 2.88}, "provenance": {"deposit_id": "SASDJD3", "doi": "10.1016/j.molcel.2021.08.024", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDJD3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM NaCl, 5 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Ubiquitin carboxyl-terminal hydrolase C266A mutant"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Polyubiquitin-C with Ubiquitin carboxyl-terminal hydrolase C266A mutant", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDJE3/", "evidence_id": "EV-SASBDB-SASDJE3", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.02, "unit": "nm", "value": 2.8}, "provenance": {"deposit_id": "SASDJE3", "doi": "10.1016/j.molcel.2021.08.024", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDJE3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2."}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM Tris, 150 mM NaCl, 1 mM TCEP", "environment": "in_vitro", "ions": [], "ligands": ["partner: Ubiquitin-conjugating enzyme E2 D1 (S22R, C85K, D87S)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 7.4 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Ubiquitin with Ubiquitin-conjugating enzyme E2 D1 (S22R, C85K, D87S)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDP34/", "evidence_id": "EV-SASBDB-SASDP34", "mappings": [], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.371, "unit": "nm", "value": 2.094}, "provenance": {"deposit_id": "SASDP34", "doi": "10.1007/s00249-022-01620-1", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDP34/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Production and characterisation of modularly deuterated UBE2D1–Ub conjugate by small angle neutron and X-ray scattering"}
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{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 7.49 nm.", "ph": 7.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Polyubiquitin-C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDSG2/", "evidence_id": "EV-SASBDB-SASDSG2", "mappings": [{"confidence": "low", "justification": "SAXS of ubiquitin alone under native conditions; samples with partners are excluded.", "rule": "ub-saxs-folded", "state_id": "Ub-folded", "who": "rule:ub-saxs-folded"}], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.226, "unit": "nm", "value": 1.995}, "provenance": {"deposit_id": "SASDSG2", "doi": "10.1039/d3dt01815f", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDSG2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Stretching the chains: the destabilizing impact of Cu(2+) and Zn(2+) ions on K48-linked diubiquitin."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.29 nm.", "ph": 7.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Polyubiquitin-C", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDSH2/", "evidence_id": "EV-SASBDB-SASDSH2", "mappings": [{"confidence": "low", "justification": "SAXS of ubiquitin alone under native conditions; samples with partners are excluded.", "rule": "ub-saxs-folded", "state_id": "Ub-folded", "who": "rule:ub-saxs-folded"}], "molecule_id": "P0CG48", "observable": {"type": "radius_of_gyration", "uncertainty": 0.209, "unit": "nm", "value": 1.923}, "provenance": {"deposit_id": "SASDSH2", "doi": "10.1039/d3dt01815f", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDSH2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Stretching the chains: the destabilizing impact of Cu(2+) and Zn(2+) ions on K48-linked diubiquitin."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-685", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P0CG48", "evidence_id": "EV-AFDB-AF-P0CG48-F1", "mappings": [{"confidence": "low", "justification": "AlphaFold prediction of the native fold (prediction).", "rule": "ub-af-folded", "state_id": "Ub-folded", "who": "rule:ub-af-folded"}], "molecule_id": "P0CG48", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 88.62}, "provenance": {"deposit_id": "AF-P0CG48-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P0CG48"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P0CG48-F1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1UBI; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A013P/overview", "evidence_id": "EV-MDDB-A013P", "mappings": [{"confidence": "low", "justification": "Simulation started from a native ubiquitin structure (prediction).", "rule": "ub-md-folded", "state_id": "Ub-folded", "who": "rule:ub-md-folded"}], "molecule_id": "P0CG48", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A013P", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A013P/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1UBI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1UBQ; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A0142/overview", "evidence_id": "EV-MDDB-A0142", "mappings": [{"confidence": "low", "justification": "Simulation started from a native ubiquitin structure (prediction).", "rule": "ub-md-folded", "state_id": "Ub-folded", "who": "rule:ub-md-folded"}], "molecule_id": "P0CG48", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A0142", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A0142/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1UBQ"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1UBQ-1"], "file": "models/P0CG48/Ub-folded.cif", "format": "mmCIF", "model_id": "Ub-folded-cif", "molecule_id": "P0CG48", "provenance": {"deposit_id": "1UBQ", "doi": "10.1016/0022-2836(87)90679-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1UBQ.cif"}, "record_type": "model", "state_id": "Ub-folded"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1UBQ-1"], "file": "models/P0CG48/Ub-folded.pdb", "format": "PDB", "model_id": "Ub-folded-pdb", "molecule_id": "P0CG48", "provenance": {"deposit_id": "1UBQ", "doi": "10.1016/0022-2836(87)90679-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1UBQ.pdb"}, "record_type": "model", "state_id": "Ub-folded"}
{"components": [], "domains": [{"end": 43, "name": "EF-hand 1", "start": 8}, {"end": 79, "name": "EF-hand 2", "start": 44}, {"end": 116, "name": "EF-hand 3", "start": 81}, {"end": 149, "name": "EF-hand 4", "start": 117}], "gene": "CALM1", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P0DP23"}, "ligands": ["Ca(2+)"], "modifications": [{"kind": "ptm", "name": "N-acetylalanine", "position": 2, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine; alternate", "position": 22, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine; by CaMK4", "position": 45, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 82, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine", "position": 95, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine", "position": 100, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 102, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine", "position": 111, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6,N6,N6-trimethyllysine; alternate", "position": 116, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-methyllysine; alternate", "position": 116, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine", "position": 139, "source": "UniProtKB"}], "molecule_id": "P0DP23", "molecule_type": "protein", "name": "Calmodulin-1", "organism": {"name": "Homo sapiens", "taxon_id": 9606}, "provenance": {"deposit_id": "P0DP23", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DP23/entry"}, "record_type": "molecule", "sequence": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "sequence_length": 149}
{"assumptions": [], "basis": "observed", "description": "Four Ca2+ bound, two lobes separated by the central helix, as in 1CLL.", "family_label": null, "molecule_id": "P0DP23", "name": "Ca2+-saturated, extended", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P0DP23.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P0DP23.yaml"}, "record_type": "state", "representative_model": "CaM-Ca4-extended-cif", "secondary_structure": null, "state_id": "CaM-Ca4-extended", "status": "draft"}
{"assumptions": [], "basis": "observed", "description": "Four Ca2+ bound with trifluoperazine; lobes collapse around the drug, as in 1CTR.", "family_label": null, "molecule_id": "P0DP23", "name": "Ca2+-saturated, collapsed (trifluoperazine-bound)", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P0DP23.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P0DP23.yaml"}, "record_type": "state", "representative_model": "CaM-Ca4-collapsed-cif", "secondary_structure": null, "state_id": "CaM-Ca4-collapsed", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1C6W"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains A,B,H,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/10NL", "evidence_id": "EV-PDB-10NL-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.81}, "provenance": {"deposit_id": "10NL", "doi": "10.1126/sciadv.aef8456", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/10NL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Xenopus KCNQ1 in complex with UCL2077"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CALMODULIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CDL", "evidence_id": "EV-PDB-1CDL-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1CDL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CDL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "EOH"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CALMODULIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CLL", "evidence_id": "EV-PDB-1CLL-1", "mappings": [{"confidence": "high", "justification": "Four Ca2+ bound, extended dumbbell; representative for CaM-Ca4-extended.", "rule": "curator_assignment", "state_id": "CaM-Ca4-extended", "who": "curator:draft (unreviewed)"}], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "1CLL", "doi": "10.1016/0022-2836(92)90324-D", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CLL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CALMODULIN STRUCTURE REFINED AT 1.7 ANGSTROMS RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MYR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -183.15}, "construct": {"description": "CALMODULIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1L7Z", "evidence_id": "EV-PDB-1L7Z-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "1L7Z", "doi": "10.1038/sj.emboj.7600093", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1L7Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Ca2+/Calmodulin complexed with myristoylated CAP-23/NAP-22 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CMP", "POP", "YB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin (chains D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1SK6", "evidence_id": "EV-PDB-1SK6-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "1SK6", "doi": "10.1074/jbc.M402689200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1SK6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F3Z", "evidence_id": "EV-PDB-2F3Z-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "2F3Z", "doi": "10.1016/j.str.2005.09.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F3Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Calmodulin/IQ-AA domain complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACE", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin-1 (chains AAA)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BF1", "evidence_id": "EV-PDB-7BF1-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.24}, "provenance": {"deposit_id": "7BF1", "doi": "10.1016/j.crstbi.2021.05.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BF1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ca2+-Calmodulin in complex with peptide from brain-type creatine kinase in extended 1:2 binding mode"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Calmodulin-1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZBI", "evidence_id": "EV-PDB-6ZBI-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6ZBI", "doi": "10.7554/eLife.60889", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZBI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Ternary complex of Calmodulin bound to 2 molecules of NHE1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin-1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YNU", "evidence_id": "EV-PDB-6YNU-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "6YNU", "doi": "10.1002/advs.202003630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YNU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CaM-P458 complex (crystal form 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin-1 (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YNS", "evidence_id": "EV-PDB-6YNS-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.94}, "provenance": {"deposit_id": "6YNS", "doi": "10.1002/advs.202003630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YNS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CaM-P458 complex (crystal form 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "rsCGaMP (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YA9", "evidence_id": "EV-PDB-6YA9-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "6YA9", "doi": "10.1038/s41587-021-01100-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YA9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of rsGCaMP in the ON state (non-illuminated)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": 24.95}, "construct": {"description": "Calmodulin (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Y95", "evidence_id": "EV-PDB-6Y95-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6Y95", "doi": "10.1074/jbc.RA120.013430", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Y95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Ca2+-free Calmodulin mutant N53I"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Y4P", "evidence_id": "EV-PDB-6Y4P-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.13325578805}, "provenance": {"deposit_id": "6Y4P", "doi": "10.1074/jbc.RA120.013430", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Y4P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin-2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Y4O", "evidence_id": "EV-PDB-6Y4O-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83549081766}, "provenance": {"deposit_id": "6Y4O", "doi": "10.1074/jbc.RA120.013430", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Y4O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains C,F,I,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6X36", "evidence_id": "EV-PDB-6X36-3", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.7}, "provenance": {"deposit_id": "6X36", "doi": "10.1038/s41467-021-21141-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6X36"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Pig R615C RyR1 in complex with CaM, EGTA (class 3, closed)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains C,F,I,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6X35", "evidence_id": "EV-PDB-6X35-3", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "6X35", "doi": "10.1038/s41467-021-21141-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6X35"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Pig R615C RyR1 in complex with CaM, EGTA (class 1, open)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains C,F,I,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6X33", "evidence_id": "EV-PDB-6X33-3", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "6X33", "doi": "10.1038/s41467-021-21141-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6X33"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Wt pig RyR1 in complex with apoCaM, EGTA condition (class 3, open)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PBY", "evidence_id": "EV-PDB-6PBY-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.67}, "provenance": {"deposit_id": "6PBY", "doi": "10.7554/eLife.49188", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PBX", "evidence_id": "EV-PDB-6PBX-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "6PBX", "doi": "10.7554/eLife.49188", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PBX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Calmodulin-1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N5W", "evidence_id": "EV-PDB-6N5W-3", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "6N5W", "doi": "10.1074/jbc.RA118.006857", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N5W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["P0T", "PIO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains C,E,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J02", "evidence_id": "EV-PDB-8J02-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8J02", "doi": "10.1038/s41467-023-42416-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J02"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state II"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -80.0}, "construct": {"description": "Calmodulin-1 (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VVD", "evidence_id": "EV-PDB-7VVD-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.134}, "provenance": {"deposit_id": "7VVD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VVD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation Q135P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "AlleyCat10 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VUT", "evidence_id": "EV-PDB-7VUT-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "7VUT", "doi": "10.1038/s41586-022-05278-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VUT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of AlleyCat10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MPD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -153.15}, "construct": {"description": "AlleyCat (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VUR", "evidence_id": "EV-PDB-7VUR-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "7VUR", "doi": "10.1038/s41586-022-05278-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VUR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of AlleyCat9 with calcium but no inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -80.15}, "construct": {"description": "Calmodulin-1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VUO", "evidence_id": "EV-PDB-7VUO-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.679}, "provenance": {"deposit_id": "7VUO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VUO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TCP", "evidence_id": "EV-PDB-7TCP-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "7TCP", "doi": "10.1038/s41467-022-31526-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TCP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Xenopus KCNQ1-CaM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "I0S"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TCI", "evidence_id": "EV-PDB-7TCI-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7TCI", "doi": "10.1038/s41467-022-31526-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TCI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Xenopus KCNQ1-CaM in complex with ML277"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D9Z", "evidence_id": "EV-PDB-9D9Z-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9D9Z", "doi": "10.1038/s41586-025-09074-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D9Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human UBR4-KCMF1-CaM E3 ligase complex (Silencing Factor of the Integrated stress response, SiFI)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1LWZ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XO1", "evidence_id": "EV-PDB-8XO1-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8XO1", "doi": "10.1016/j.celrep.2025.116771", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XO1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human KCNQ2-CaM in complex with QO-83"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UXM", "evidence_id": "EV-PDB-8UXM-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "8UXM", "doi": "10.1038/s41467-024-51791-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UXM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SIN", "evidence_id": "EV-PDB-8SIN-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.8}, "provenance": {"deposit_id": "8SIN", "doi": "10.1073/pnas.2301985120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SIN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "KCNQ1 with voltage sensor in the down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 34.85}, "construct": {"description": "Calmodulin-1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PQI", "evidence_id": "EV-PDB-9PQI-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9PQI", "doi": "10.1016/j.jbc.2026.111131", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PQI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR Structure of Ca2+/Calmodulin bound to the GluN2A C0 domain of the NMDA receptor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QWS", "evidence_id": "EV-PDB-9QWS-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9QWS", "doi": "10.1126/science.adv9309", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QWS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human UBR4/KCMF1/CALM1 complex (C-term dimer interface focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QWU", "evidence_id": "EV-PDB-9QWU-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9QWU", "doi": "10.1126/science.adv9309", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QWU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human UBR4/KCMF1/CALM1 complex (CALM1 focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QX0", "evidence_id": "EV-PDB-9QX0-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9QX0", "doi": "10.1126/science.adv9309", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QX0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human UBR4/KCMF1/CALM1 complex (C-term focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "K", "PT5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,E,H,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9U7F", "evidence_id": "EV-PDB-9U7F-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9U7F", "doi": "10.1038/s41422-025-01182-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9U7F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "structure of human KCNQ1-KCNE1-CaM complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "K", "PC1"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UJ4", "evidence_id": "EV-PDB-9UJ4-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "9UJ4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UJ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human KCNQ1-CaM complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UPG", "evidence_id": "EV-PDB-9UPG-4", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.87}, "provenance": {"deposit_id": "9UPG", "doi": "10.1038/s41467-025-64436-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UPG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human olfactory CNGA2/A4/B1 in CaM-bound closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,E,H,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VEC", "evidence_id": "EV-PDB-9VEC-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9VEC", "doi": "10.1038/s41422-025-01152-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "structure of human KCNQ1-KCNE1-CaM complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PT5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,E,H,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VEI", "evidence_id": "EV-PDB-9VEI-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "9VEI", "doi": "10.1038/s41422-025-01152-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VEI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "structure of human KCNQ1-KCNE1-CaM complex with PIP2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PT5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VEN", "evidence_id": "EV-PDB-9VEN-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9VEN", "doi": "10.1038/s41422-025-01152-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VEN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "structure of human KCNQ1-CaM-PIP2 complex with bent conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ETX", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VU9", "evidence_id": "EV-PDB-9VU9-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34}, "provenance": {"deposit_id": "9VU9", "doi": "10.1038/s41467-026-68475-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VU9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "channel D complex with 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "POV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUA", "evidence_id": "EV-PDB-9VUA-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.23}, "provenance": {"deposit_id": "9VUA", "doi": "10.1038/s41467-026-68475-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "channel A complex with 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1B92", "CA", "CLR", "K", "POV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUB", "evidence_id": "EV-PDB-9VUB-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "9VUB", "doi": "10.1038/s41467-026-68475-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "channel C complex with 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "Y7Z"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VUC", "evidence_id": "EV-PDB-9VUC-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "9VUC", "doi": "10.1038/s41467-026-68475-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VUC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "channel B complex with 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1BBG", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains B,E,H,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WD8", "evidence_id": "EV-PDB-9WD8-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "9WD8", "doi": "10.1038/s41422-025-01152-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WD8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "structure of human KCNQ1-KCNE3-CaM complex with two PIP2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9X5J", "evidence_id": "EV-PDB-9X5J-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "9X5J", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9X5J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human KCNQ2/3 heteromer channel"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EY8", "K", "PIO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9X65", "evidence_id": "EV-PDB-9X65-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "9X65", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9X65"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human KCNQ2/3 heteromer channel in the XEN1101-bound open state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1LVR", "PIO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XB9", "evidence_id": "EV-PDB-9XB9-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9XB9", "doi": "10.1016/j.celrep.2025.116771", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XB9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human KCNQ2-CaM in complex with QO-58 and PIP2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1LWZ", "PIO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XED", "evidence_id": "EV-PDB-9XED-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9XED", "doi": "10.1016/j.celrep.2025.116771", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XED"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human KCNQ2-CaM in complex with QO-83 and PIP2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains D,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XTI", "evidence_id": "EV-PDB-9XTI-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "9XTI", "doi": "10.1093/procel/pwag036", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The focused structure of the C-terminal lobe of the human UBR4-KCMF1-Calmodulin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains D,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XTJ", "evidence_id": "EV-PDB-9XTJ-3", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.89}, "provenance": {"deposit_id": "9XTJ", "doi": "10.1093/procel/pwag036", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Overall structure of the human UBR4-KCMF1-Calmodulin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1B92", "CA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Y5Q", "evidence_id": "EV-PDB-9Y5Q-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.73}, "provenance": {"deposit_id": "9Y5Q", "doi": "10.1038/s41467-025-67232-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Y5Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of KCa3.1_R355K_I/calmodulin channel in complex with rimtuzalcap"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YDZ", "evidence_id": "EV-PDB-9YDZ-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9YDZ", "doi": "10.1038/s41467-025-67232-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YDZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of KCa3.1_R355K_II/calmodulin channel in complex with rimtuzalcap"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YG4", "evidence_id": "EV-PDB-9YG4-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "9YG4", "doi": "10.1016/j.cell.2026.05.027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YG4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VPS13A/Nt-CaM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YQP", "evidence_id": "EV-PDB-9YQP-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "9YQP", "doi": "10.1016/j.molcel.2026.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YQP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the VPS13C N-terminal region in complex with Calmodulin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YRM", "evidence_id": "EV-PDB-9YRM-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "9YRM", "doi": "10.1016/j.molcel.2026.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YRM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM Structure of VPS13 protein, 1-1390 from C. thermophilum, in complex with calmodulin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YRP", "evidence_id": "EV-PDB-9YRP-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.13}, "provenance": {"deposit_id": "9YRP", "doi": "10.1016/j.molcel.2026.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YRP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Full-length human VPS13C in complex with calmodulin from the CryoEM composite map"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["43M", "ADP", "CA", "CFF", "U1C", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZN6", "evidence_id": "EV-PDB-9ZN6-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.58}, "provenance": {"deposit_id": "9ZN6", "doi": "10.1038/s41467-026-76519-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of rabbit RyR1 complexed with FKBP12.6 and calmodulin in the presence of dantrolene, ADP, 4-chloro-m-cresol, caffeine, and Mg2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZN7", "evidence_id": "EV-PDB-9ZN7-2", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.23}, "provenance": {"deposit_id": "9ZN7", "doi": "10.1038/s41467-026-76519-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZN7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of rabbit RyR1 complexed with FKBP12.6 and calmodulin in the presence of ATP, ADP, and Mg2+ (mimicking muscle fatigue)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Calmodulin-1 (chains I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZN8", "evidence_id": "EV-PDB-9ZN8-1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "9ZN8", "doi": "10.1038/s41467-026-76519-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZN8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of rabbit RyR1 complexed with FKBP12.6 and calmodulin in the presence of ATP, ADP, and Mg2+ (mimicking physiological conditions)"}
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{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES pH 7.5, 150 mM NaCl, 5 mM CaCl2", "environment": "in_vitro", "ions": [], "ligands": ["partner: P2X purinoceptor 7"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 13.53 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Calmodulin-1 with P2X purinoceptor 7", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPF4/", "evidence_id": "EV-SASBDB-SASDPF4", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "radius_of_gyration", "uncertainty": 0.014, "unit": "nm", "value": 3.24}, "provenance": {"deposit_id": "SASDPF4", "doi": "10.1016/j.jbc.2022.102495", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPF4/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "New insights into P2X7 receptor regulation: Ca<sup>2+</sup>-calmodulin and GDP bind to the soluble P2X7 ballast domain."}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM HEPES, 100 mM NaCl, 2 mM CaCl2, 1 mM TCEP", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 7 nm.", "ph": 7.4, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "Calmodulin-1", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPV6/", "evidence_id": "EV-SASBDB-SASDPV6", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "radius_of_gyration", "uncertainty": 0.069, "unit": "nm", "value": 2.178}, "provenance": {"deposit_id": "SASDPV6", "doi": "10.1002/pro.4606", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPV6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Binding by calmodulin is coupled to transient unfolding of the third FF domain of Prp40A."}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM HEPES, 100 mM NaCl, 2 mM CaCl2, 1 mM TCEP", "environment": "in_vitro", "ions": [], "ligands": ["partner: Pre-mRNA-processing factor 40 homolog A"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.7 nm.", "ph": 7.4, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "Calmodulin-1 with Pre-mRNA-processing factor 40 homolog A", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPX6/", "evidence_id": "EV-SASBDB-SASDPX6", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "radius_of_gyration", "uncertainty": 0.078, "unit": "nm", "value": 2.4}, "provenance": {"deposit_id": "SASDPX6", "doi": "10.1002/pro.4606", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPX6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Binding by calmodulin is coupled to transient unfolding of the third FF domain of Prp40A."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 76-85; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/34480001", "evidence_id": "EV-DISPROT-DP02013r002", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 10}, "provenance": {"deposit_id": "DP02013r002", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02013"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP02013: disorder, residues 76-85"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 76-85; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/34480001", "evidence_id": "EV-DISPROT-DP02013r003", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 10}, "provenance": {"deposit_id": "DP02013r003", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02013"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP02013: order to disorder, residues 76-85"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-149", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P0DP23", "evidence_id": "EV-AFDB-AF-P0DP23-F1", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 85.25}, "provenance": {"deposit_id": "AF-P0DP23-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P0DP23"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P0DP23-F1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1CDL; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A007P/overview", "evidence_id": "EV-MDDB-A007P", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A007P", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A007P/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1CDL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 2F3Y; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A00EU/overview", "evidence_id": "EV-MDDB-A00EU", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A00EU", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A00EU/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 2F3Y"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 2F3Z; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A0173/overview", "evidence_id": "EV-MDDB-A0173", "mappings": [], "molecule_id": "P0DP23", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A0173", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A0173/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 2F3Z"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1CLL-1"], "file": "models/P0DP23/CaM-Ca4-extended.cif", "format": "mmCIF", "model_id": "CaM-Ca4-extended-cif", "molecule_id": "P0DP23", "provenance": {"deposit_id": "1CLL", "doi": "10.1016/0022-2836(92)90324-D", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1CLL.cif"}, "record_type": "model", "state_id": "CaM-Ca4-extended"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1CLL-1"], "file": "models/P0DP23/CaM-Ca4-extended.pdb", "format": "PDB", "model_id": "CaM-Ca4-extended-pdb", "molecule_id": "P0DP23", "provenance": {"deposit_id": "1CLL", "doi": "10.1016/0022-2836(92)90324-D", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1CLL.pdb"}, "record_type": "model", "state_id": "CaM-Ca4-extended"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1CTR-1"], "file": "models/P0DP23/CaM-Ca4-collapsed.cif", "format": "mmCIF", "model_id": "CaM-Ca4-collapsed-cif", "molecule_id": "P0DP23", "provenance": {"deposit_id": "1CTR", "doi": "10.1021/bi00255a006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1CTR.cif"}, "record_type": "model", "state_id": "CaM-Ca4-collapsed"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1CTR-1"], "file": "models/P0DP23/CaM-Ca4-collapsed.pdb", "format": "PDB", "model_id": "CaM-Ca4-collapsed-pdb", "molecule_id": "P0DP23", "provenance": {"deposit_id": "1CTR", "doi": "10.1021/bi00255a006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1CTR.pdb"}, "record_type": "model", "state_id": "CaM-Ca4-collapsed"}
{"components": [], "domains": [{"end": 303, "name": "BetaCoV S1-NTD", "start": 14}, {"end": 527, "name": "BetaCoV S1-CTD", "start": 334}], "gene": "S", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P0DTC2"}, "ligands": [], "modifications": [], "molecule_id": "P0DTC2", "molecule_type": "protein", "name": "Spike glycoprotein", "organism": {"name": "Severe acute respiratory syndrome coronavirus 2", "taxon_id": 2697049}, "provenance": {"deposit_id": "P0DTC2", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0DTC2/entry"}, "record_type": "molecule", "sequence": "MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT", "sequence_length": 1273}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "E-FICs-v3 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/11HL", "evidence_id": "EV-PDB-11HL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "11HL", "doi": "10.1038/s41594-026-01801-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/11HL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/22HG", "evidence_id": "EV-PDB-22HG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "22HG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/22HG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.3.2.2(RE.2.2) RBD in complex with human ACE2 and monoclonal antibody S2H97"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6LZG", "evidence_id": "EV-PDB-6LZG-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6LZG", "doi": "10.1016/j.cell.2020.03.045", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6LZG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of novel coronavirus spike receptor-binding domain complexed with its receptor ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6M0J", "evidence_id": "EV-PDB-6M0J-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "6M0J", "doi": "10.1038/s41586-020-2180-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6M0J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain bound with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LEU", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6M17", "evidence_id": "EV-PDB-6M17-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6M17", "doi": "10.1126/science.abb2762", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6M17"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The 2019-nCoV RBD/ACE2-B0AT1 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XM0", "evidence_id": "EV-PDB-6XM0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "6XM0", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Consensus structure of SARS-CoV-2 spike at pH 5.5"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XF5", "evidence_id": "EV-PDB-6XF5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "6XF5", "doi": "10.2139/ssrn.3639618", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XF5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a biotinylated SARS-CoV-2 spike probe in the prefusion state (RBDs down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XEY", "evidence_id": "EV-PDB-6XEY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "6XEY", "doi": "10.1038/s41586-020-2571-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XEY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XE1", "evidence_id": "EV-PDB-6XE1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "6XE1", "doi": "10.1038/s41467-020-19231-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XE1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a potent neutralizing antibody, CV30 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XDG", "evidence_id": "EV-PDB-6XDG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "6XDG", "doi": "10.1126/science.abd0827", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XDG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of two neutralizing antibodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XCN", "evidence_id": "EV-PDB-6XCN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.66}, "provenance": {"deposit_id": "6XCN", "doi": "10.1016/j.cell.2020.06.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XCN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XC7", "evidence_id": "EV-PDB-6XC7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.883}, "provenance": {"deposit_id": "6XC7", "doi": "10.1126/science.abd2321", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XC7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.3 and CR3022"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6X2C", "evidence_id": "EV-PDB-6X2C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "6X2C", "doi": "10.1038/s41594-020-0479-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6X2C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VXX", "evidence_id": "EV-PDB-6VXX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "6VXX", "doi": "10.1016/j.cell.2020.02.058", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VXX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein (closed state)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2,Spike protein S2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6M1V", "evidence_id": "EV-PDB-6M1V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "6M1V", "doi": "10.1080/22221751.2020.1770631", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6M1V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of post fusion core of 2019-nCoV S2 subunit"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/22HP", "evidence_id": "EV-PDB-22HP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "22HP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/22HP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.3.2.2(RE.2.2) RBD in complex with monoclonal antibodies S2K146 and L4.65"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "E-FICs-v3 (chains A,B,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/11HW", "evidence_id": "EV-PDB-11HW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "11HW", "doi": "10.1038/s41594-026-01801-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/11HW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (Fab local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/11HN", "evidence_id": "EV-PDB-11HN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "11HN", "doi": "10.1038/s41594-026-01801-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/11HN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "E-FICS-v3 (chains A,D,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/11HK", "evidence_id": "EV-PDB-11HK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "11HK", "doi": "10.1038/s41594-026-01801-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/11HK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (Fab local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/10MU", "evidence_id": "EV-PDB-10MU-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "10MU", "doi": "10.64898/2026.02.18.706653", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/10MU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 in complex with polyclonal Fab_Donor2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XM5", "evidence_id": "EV-PDB-6XM5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "6XM5", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XM5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike at pH 5.5, all RBDs down"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z43", "evidence_id": "EV-PDB-6Z43-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6Z43", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z43"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZB5", "evidence_id": "EV-PDB-6ZB5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "6ZB5", "doi": "10.1126/science.abd3255", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 Spike protein, Closed conformation, C3 symmetry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZDH", "evidence_id": "EV-PDB-6ZDH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "6ZDH", "doi": "10.1038/s41594-020-0480-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZDH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike glycoprotein in complex with a neutralizing antibody EY6A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZGI", "evidence_id": "EV-PDB-6ZGI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6ZGI", "doi": "10.1038/s41594-020-0468-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZGI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Furin Cleaved Spike Protein of SARS-CoV-2 in Closed Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZHD", "evidence_id": "EV-PDB-6ZHD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "6ZHD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZHD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "H11-H4 bound to Spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZOX", "evidence_id": "EV-PDB-6ZOX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "6ZOX", "doi": "10.1038/s41594-020-0478-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZOX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZP1", "evidence_id": "EV-PDB-6ZP1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6ZP1", "doi": "10.1038/s41594-020-0478-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZP1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "MAN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZP7", "evidence_id": "EV-PDB-6ZP7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6ZP7", "doi": "10.1107/S2052252520012725", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZP7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up open conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A29", "evidence_id": "EV-PDB-7A29-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.94}, "provenance": {"deposit_id": "7A29", "doi": "10.1038/s41467-020-19204-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A29"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A95", "evidence_id": "EV-PDB-7A95-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7A95", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound and 1 RBD Erect in Clockwise Direction"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A94", "evidence_id": "EV-PDB-7A94-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7A94", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A94"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A93", "evidence_id": "EV-PDB-7A93-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.9}, "provenance": {"deposit_id": "7A93", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A93"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with 2 RBDs Erect"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A92", "evidence_id": "EV-PDB-7A92-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7A92", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A92"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of SARS-CoV-2 Spike bound to ACE2 (Unmasked Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A91", "evidence_id": "EV-PDB-7A91-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7A91", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A91"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A5S", "evidence_id": "EV-PDB-7A5S-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7A5S", "doi": "10.1038/s41467-020-19146-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A5S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex of SARS-CoV-2 spike and CR3022 Fab (Homogeneous Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A5R", "evidence_id": "EV-PDB-7A5R-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7A5R", "doi": "10.1038/s41467-020-19146-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A5R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex of SARS-CoV-2 spike and CR3022 Fab (Non-Uniform Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A4N", "evidence_id": "EV-PDB-7A4N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "7A4N", "doi": "10.1038/s41467-020-20321-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A4N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(S-closed trimer)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A25", "evidence_id": "EV-PDB-7A25-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "7A25", "doi": "10.1038/s41467-020-19204-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZXN", "evidence_id": "EV-PDB-6ZXN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.93}, "provenance": {"deposit_id": "6ZXN", "doi": "10.1038/s41467-020-18174-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZXN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing nanobodies (Ty1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZWV", "evidence_id": "EV-PDB-6ZWV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "6ZWV", "doi": "10.1038/s41586-020-2665-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZWV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: 3 Closed RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "MAN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZP5", "evidence_id": "EV-PDB-6ZP5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "6ZP5", "doi": "10.1107/S2052252520012725", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZP5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up closed conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZP2", "evidence_id": "EV-PDB-6ZP2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "6ZP2", "doi": "10.1038/s41594-020-0478-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZP2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZP0", "evidence_id": "EV-PDB-6ZP0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "6ZP0", "doi": "10.1038/s41594-020-0478-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZP0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZOZ", "evidence_id": "EV-PDB-6ZOZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "6ZOZ", "doi": "10.1038/s41594-020-0478-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZOZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Locked State"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZOY", "evidence_id": "EV-PDB-6ZOY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "6ZOY", "doi": "10.1038/s41594-020-0478-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZOY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMS", "MAN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,a)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZOW", "evidence_id": "EV-PDB-6ZOW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "6ZOW", "doi": "10.1107/S2052252520012725", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in prefusion state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.7, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains AAA,DDD,EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZLR", "evidence_id": "EV-PDB-6ZLR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "6ZLR", "doi": "10.3389/fphar.2020.615211", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZLR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Soaking competent crystal form of the SARS-CoV-2 Receptor Binding Domain (RBD):CR3022 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZH9", "evidence_id": "EV-PDB-6ZH9-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31}, "provenance": {"deposit_id": "6ZH9", "doi": "10.1038/s41594-020-0469-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZH9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ternary complex CR3022 H11-H4 and RBD (SARS-CoV-2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZGH", "evidence_id": "EV-PDB-6ZGH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.8}, "provenance": {"deposit_id": "6ZGH", "doi": "10.1038/s41594-020-0468-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZGH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Furin Cleaved Spike Protein of SARS-CoV-2 in Intermediate Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZGG", "evidence_id": "EV-PDB-6ZGG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "6ZGG", "doi": "10.1038/s41594-020-0468-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZGG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Furin Cleaved Spike Protein of SARS-CoV-2 with One RBD Erect"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZGE", "evidence_id": "EV-PDB-6ZGE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "6ZGE", "doi": "10.1038/s41594-020-0468-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZGE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Uncleavable Spike Protein of SARS-CoV-2 in Closed Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZFO", "evidence_id": "EV-PDB-6ZFO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "6ZFO", "doi": "10.1038/s41594-020-0480-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZFO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Association of two complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZER", "evidence_id": "EV-PDB-6ZER-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "6ZER", "doi": "10.1038/s41594-020-0480-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZER"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with EY6A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZDG", "evidence_id": "EV-PDB-6ZDG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.7}, "provenance": {"deposit_id": "6ZDG", "doi": "10.1038/s41594-020-0480-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZDG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MG", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZCZ", "evidence_id": "EV-PDB-6ZCZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "6ZCZ", "doi": "10.1038/s41594-020-0480-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZCZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZBP", "evidence_id": "EV-PDB-6ZBP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "6ZBP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZBP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H11-H4 complex with SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZB4", "evidence_id": "EV-PDB-6ZB4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "6ZB4", "doi": "10.1126/science.abd3255", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 Spike protein, Closed conformation, C1 symmetry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z97", "evidence_id": "EV-PDB-6Z97-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6Z97", "doi": "10.1016/j.chom.2020.06.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z97"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the prefusion SARS-CoV-2 spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Z2M", "evidence_id": "EV-PDB-6Z2M-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "6Z2M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Z2M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H11-D4, SARS-CoV-2 RBD, CR3022 ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains AAA,EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YZ7", "evidence_id": "EV-PDB-6YZ7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6YZ7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YZ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H11-D4, SARS-CoV-2 RBD, CR3022 ternary complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YOR", "evidence_id": "EV-PDB-6YOR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6YOR", "doi": "10.1016/j.chom.2020.06.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YOR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike S1 protein in complex with CR3022 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YM0", "evidence_id": "EV-PDB-6YM0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.36}, "provenance": {"deposit_id": "6YM0", "doi": "10.1016/j.chom.2020.06.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab (crystal form 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "DMS", "MLI", "NAG", "PG0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YLA", "evidence_id": "EV-PDB-6YLA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.42}, "provenance": {"deposit_id": "6YLA", "doi": "10.1016/j.chom.2020.06.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YLA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XS6", "evidence_id": "EV-PDB-6XS6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "6XS6", "doi": "10.1016/j.cell.2020.09.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XS6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike D614G variant, minus RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MAN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XRA", "evidence_id": "EV-PDB-6XRA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "6XRA", "doi": "10.1126/science.abd4251", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XRA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Distinct conformational states of SARS-CoV-2 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XR8", "evidence_id": "EV-PDB-6XR8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6XR8", "doi": "10.1126/science.abd4251", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XR8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Distinct conformational states of SARS-CoV-2 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XM4", "evidence_id": "EV-PDB-6XM4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6XM4", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XM4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike at pH 5.5, single RBD up, conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XM3", "evidence_id": "EV-PDB-6XM3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6XM3", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XM3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike at pH 5.5, single RBD up, conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A96", "evidence_id": "EV-PDB-7A96-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8}, "provenance": {"deposit_id": "7A96", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A96"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound and 1 RBD Erect in Anticlockwise Direction"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A97", "evidence_id": "EV-PDB-7A97-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7A97", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A97"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with 2 ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7A98", "evidence_id": "EV-PDB-7A98-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.4}, "provenance": {"deposit_id": "7A98", "doi": "10.1038/s41586-020-2772-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7A98"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with 3 ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BH9", "evidence_id": "EV-PDB-7BH9-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7BH9", "doi": "10.1038/s41564-021-00954-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BH9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD-62 in complex with ACE2 peptidase domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BNN", "evidence_id": "EV-PDB-7BNN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7BNN", "doi": "10.1073/pnas.2022586118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BNN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Open conformation of D614G SARS-CoV-2 spike with 1 Erect RBD"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BWJ", "evidence_id": "EV-PDB-7BWJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7BWJ", "doi": "10.1038/s41586-020-2380-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "crystal structure of SARS-CoV-2 antibody with RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Surface glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BNV", "evidence_id": "EV-PDB-7BNV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "7BNV", "doi": "10.3389/fimmu.2021.678570", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BNV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the SARS-CoV-2 Receptor Binding Domain in Complex with Antibody ION-300"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BNM", "evidence_id": "EV-PDB-7BNM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7BNM", "doi": "10.1073/pnas.2022586118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BNM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Closed conformation of D614G SARS-CoV-2 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GLU", "GLY", "GOL", "IMD", "PEG", "PG4", "PGE", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEP", "evidence_id": "EV-PDB-7BEP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "7BEP", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-384 and S309 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "GOL", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains R,X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEO", "evidence_id": "EV-PDB-7BEO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "7BEO", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-253H55L and COVOX-75 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BR", "GOL", "IMD", "IOD", "PEG", "PG6", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEN", "evidence_id": "EV-PDB-7BEN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7BEN", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-253 and COVOX-75 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "PO4", "PRO", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEM", "evidence_id": "EV-PDB-7BEM-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.52}, "provenance": {"deposit_id": "7BEM", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-269 scFv"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "GOL", "NAG", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains R,X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEL", "evidence_id": "EV-PDB-7BEL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.53}, "provenance": {"deposit_id": "7BEL", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-88 and COVOX-45 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "PEG", "SO4", "TRS", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEK", "evidence_id": "EV-PDB-7BEK-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.04}, "provenance": {"deposit_id": "7BEK", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-158 Fab (crystal form 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FMT", "GOL", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEJ", "evidence_id": "EV-PDB-7BEJ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.42}, "provenance": {"deposit_id": "7BEJ", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-158 Fab (crystal form 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NO3", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEI", "evidence_id": "EV-PDB-7BEI-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7BEI", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-150 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "TRS", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7BEH", "evidence_id": "EV-PDB-7BEH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7BEH", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7BEH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-316 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "BLA", "NAG", "PEG", "PG4", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B62", "evidence_id": "EV-PDB-7B62-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82}, "provenance": {"deposit_id": "7B62", "doi": "10.1126/sciadv.abg7607", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B62"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein N-terminal domain in complex with biliverdin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B3O", "evidence_id": "EV-PDB-7B3O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "7B3O", "doi": "10.1016/j.celrep.2021.109433", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B3O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD in complex with STE90-C11 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B18", "evidence_id": "EV-PDB-7B18-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.62}, "provenance": {"deposit_id": "7B18", "doi": "10.1126/science.abe6230", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B18"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-spike bound to two neutralising nanobodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B17", "evidence_id": "EV-PDB-7B17-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.01}, "provenance": {"deposit_id": "7B17", "doi": "10.1126/science.abe6230", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B17"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-spike RBD bound to two neutralising nanobodies."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B14", "evidence_id": "EV-PDB-7B14-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.79}, "provenance": {"deposit_id": "7B14", "doi": "10.1126/science.abe6230", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Nanobody E bound to Spike-RBD in a localized reconstruction"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Surface glycoprotein (chains F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7B0B", "evidence_id": "EV-PDB-7B0B-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "7B0B", "doi": "10.1016/j.immuni.2023.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7B0B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FUC", "MAN", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(3-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7AKD", "evidence_id": "EV-PDB-7AKD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7AKD", "doi": "10.1126/sciadv.abf5632", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7AKD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Envelope glycoprotein,Spike glycoprotein,Envelope glycoprotein,SARS-CoV-2 S protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7AD1", "evidence_id": "EV-PDB-7AD1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "7AD1", "doi": "10.1038/s41467-020-20321-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7AD1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(One up trimer)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,D,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DCX", "evidence_id": "EV-PDB-7DCX-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.9}, "provenance": {"deposit_id": "7DCX", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DCX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-3C1-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 3C1 fab."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DDN", "evidence_id": "EV-PDB-7DDN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.3}, "provenance": {"deposit_id": "7DDN", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DDN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 S protein at open state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DF3", "evidence_id": "EV-PDB-7DF3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7DF3", "doi": "10.1126/sciadv.abe5575", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DF3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S trimer, S-closed"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DEU", "evidence_id": "EV-PDB-7DEU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "7DEU", "doi": "10.1371/journal.pbio.3001209", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DEU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DET", "evidence_id": "EV-PDB-7DET-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "7DET", "doi": "10.1371/journal.pbio.3001209", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DET"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DEO", "evidence_id": "EV-PDB-7DEO-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7DEO", "doi": "10.1371/journal.pbio.3001209", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DEO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DDO", "evidence_id": "EV-PDB-7DDO-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7DDO", "doi": "10.15252/embj.2021107786", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DDO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human ACE2 and GD/1/2019 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DDD", "evidence_id": "EV-PDB-7DDD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7DDD", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DDD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 S protein at close state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DD8", "evidence_id": "EV-PDB-7DD8-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.5}, "provenance": {"deposit_id": "7DD8", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DD8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-3C1-F1 structure, one RBD is up and two RBDs are down, the up RBD binds with a 3C1 fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,D,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DD2", "evidence_id": "EV-PDB-7DD2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.6}, "provenance": {"deposit_id": "7DD2", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DD2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-3C1-F2 structure, two RBDs are up and one RBD is down, the two up RBD bind with a 3C1 fab."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E,I,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DCC", "evidence_id": "EV-PDB-7DCC-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7DCC", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DCC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-3C1-F3b structure, all the three RBDs are in the up conformation and each of them associates with a 3C1 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D6I", "evidence_id": "EV-PDB-7D6I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "7D6I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D6I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A neutralizing MAb targeting receptor-binding-domain of SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D4G", "evidence_id": "EV-PDB-7D4G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7D4G", "doi": "10.1093/nsr/nwab053", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D4G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "ACT", "BU2", "CD", "GOL", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D30", "evidence_id": "EV-PDB-7D30-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "7D30", "doi": "10.1371/journal.ppat.1009328", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D30"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of sybody MR17-SR31 fusion in complex with the SARS-CoV-2 S Receptor Binding domain (RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "FMT", "GOL", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D2Z", "evidence_id": "EV-PDB-7D2Z-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.97}, "provenance": {"deposit_id": "7D2Z", "doi": "10.1371/journal.ppat.1009328", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D2Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of sybody SR31 in complex with the SARS-CoV-2 S Receptor Binding domain (RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D0D", "evidence_id": "EV-PDB-7D0D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7D0D", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D0D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P5A-3C12_2B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D0C", "evidence_id": "EV-PDB-7D0C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7D0C", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D0C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P5A-3A1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D0B", "evidence_id": "EV-PDB-7D0B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7D0B", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D0B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P5A-3C12_1B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D03", "evidence_id": "EV-PDB-7D03-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7D03", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D03"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with FabP5A-2G7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7D00", "evidence_id": "EV-PDB-7D00-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7D00", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7D00"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with FabP5A-1B8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CZZ", "evidence_id": "EV-PDB-7CZZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7CZZ", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CZZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P5A-2F11_3B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CZY", "evidence_id": "EV-PDB-7CZY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7CZY", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CZY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P5A-2F11_2B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CZX", "evidence_id": "EV-PDB-7CZX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7CZX", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CZX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P5A-1B9"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CZV", "evidence_id": "EV-PDB-7CZV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7CZV", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CZV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P5A-1B6_3B"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CZQ", "evidence_id": "EV-PDB-7CZQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7CZQ", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CZQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P2B-1A10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CZP", "evidence_id": "EV-PDB-7CZP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7CZP", "doi": "10.1038/s41422-021-00487-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CZP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in complex bound with P2B-1A1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CYV", "evidence_id": "EV-PDB-7CYV-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "7CYV", "doi": "10.15252/emmm.202114544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CYV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "SARS-CoV-2 Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CYP", "evidence_id": "EV-PDB-7CYP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7CYP", "doi": "10.1093/nsr/nwaa297", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CYP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CYH", "evidence_id": "EV-PDB-7CYH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7CYH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Binding interface of SARS-CoV-2 RBD and its neutralizing antibody HB27"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CWU", "evidence_id": "EV-PDB-7CWU-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7CWU", "doi": "10.1038/s41422-020-00446-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CWU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike proteins trimer in complex with P17 and FC05 Fabs cocktail"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CWT", "evidence_id": "EV-PDB-7CWT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7CWT", "doi": "10.1038/s41422-020-00446-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CWT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with hb27 and fc05 Fab cocktail"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains O,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CWS", "evidence_id": "EV-PDB-7CWS-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7CWS", "doi": "10.1038/s41422-020-00446-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CWS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Proteins Trimer in Complex with FC05 and H014 Fabs Cocktail"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CWO", "evidence_id": "EV-PDB-7CWO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7CWO", "doi": "10.1038/s41422-020-00444-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CWO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein RBD and P17 fab complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CWN", "evidence_id": "EV-PDB-7CWN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7CWN", "doi": "10.1038/s41422-020-00444-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CWN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CWM", "evidence_id": "EV-PDB-7CWM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7CWM", "doi": "10.1038/s41422-020-00444-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CWM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex of SARS-CoV-2 spike protein and Fab P17 with one RBD in open state and two RBD in closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CWL", "evidence_id": "EV-PDB-7CWL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7CWL", "doi": "10.1038/s41422-020-00444-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CWL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein and P17 fab complex with one RBD in close state"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7CHS", "evidence_id": "EV-PDB-7CHS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.401}, "provenance": {"deposit_id": "7CHS", "doi": "10.1038/s41467-021-24514-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7CHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 antibody P22A-1D1 with RBD"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DK0", "evidence_id": "EV-PDB-7DK0-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.199}, "provenance": {"deposit_id": "7DK0", "doi": "10.1038/s42003-022-03207-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DK0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,F,I,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DK2", "evidence_id": "EV-PDB-7DK2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7DK2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DK2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Spike RBD in complex with MW07 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DK3", "evidence_id": "EV-PDB-7DK3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.0}, "provenance": {"deposit_id": "7DK3", "doi": "10.1126/sciadv.abe5575", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DK3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S trimer, S-open"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DK4", "evidence_id": "EV-PDB-7DK4-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7DK4", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DK4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-2H2-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 2H2 Fab."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DK5", "evidence_id": "EV-PDB-7DK5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 13.5}, "provenance": {"deposit_id": "7DK5", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DK5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-2H2-F1 structure, one RBD is up and two RBDs are down, only up RBD binds with a 2H2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DK6", "evidence_id": "EV-PDB-7DK6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7DK6", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DK6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-2H2-F2 structure, two RBDs are up and one RBD is down, each up RBD binds with a 2H2 Fab."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DK7", "evidence_id": "EV-PDB-7DK7-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 9.7}, "provenance": {"deposit_id": "7DK7", "doi": "10.1038/s41467-020-20465-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DK7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-2H2-F3b structure, three RBDs are up and each RBD binds with a 2H2 Fab."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DMU", "evidence_id": "EV-PDB-7DMU-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7DMU", "doi": "10.1038/s41467-021-24013-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DMU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 spike receptor-binding domain complexed with high affinity ACE2 mutant 3N39"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,F,I,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DPM", "evidence_id": "EV-PDB-7DPM-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.304}, "provenance": {"deposit_id": "7DPM", "doi": "10.1080/19420862.2021.1953683", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DPM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DQA", "evidence_id": "EV-PDB-7DQA-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7DQA", "doi": "10.52601/bpr.2021.210007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DQA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LEU", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DWX", "evidence_id": "EV-PDB-7DWX-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 8.3}, "provenance": {"deposit_id": "7DWX", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DWX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Conformation 1 of S-ACE2-B0AT1 ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DWY", "evidence_id": "EV-PDB-7DWY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7DWY", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DWY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in the locked conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DWZ", "evidence_id": "EV-PDB-7DWZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7DWZ", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DWZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 in the active conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX0", "evidence_id": "EV-PDB-7DX0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7DX0", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trypsin-digested S protein of SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX1", "evidence_id": "EV-PDB-7DX1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7DX1", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 D614G mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX2", "evidence_id": "EV-PDB-7DX2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7DX2", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trypsin-digested S protein of SARS-CoV-2 D614G mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX4", "evidence_id": "EV-PDB-7DX4-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7DX4", "doi": "10.1093/nsr/nwab053", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of FC08 Fab-hA.CE2-RBD complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX5", "evidence_id": "EV-PDB-7DX5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7DX5", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 2 (1 up RBD and 1 PD bound)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX6", "evidence_id": "EV-PDB-7DX6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7DX6", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 3 (2 up RBD and 1 PD bound)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX7", "evidence_id": "EV-PDB-7DX7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7DX7", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 1 (1 up RBD and 1 PD bound)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX8", "evidence_id": "EV-PDB-7DX8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7DX8", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 2 (2 up RBD and 2 PD bound)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DZW", "evidence_id": "EV-PDB-7DZW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "7DZW", "doi": "10.1016/j.cell.2021.05.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DZW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Apo spike protein from SARS-CoV2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DZX", "evidence_id": "EV-PDB-7DZX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "7DZX", "doi": "10.1016/j.cell.2021.05.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DZX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike protein from SARS-CoV2 with Fab fragment of enhancing antibody 8D2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DZY", "evidence_id": "EV-PDB-7DZY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7DZY", "doi": "10.1016/j.cell.2021.05.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DZY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike protein from SARS-CoV2 with Fab fragment of enhancing antibody 2490"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EB4", "evidence_id": "EV-PDB-7EB4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7EB4", "doi": "10.1016/j.jbc.2021.101238", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike D614G variant, two RBD-up conformation 1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EDJ", "evidence_id": "EV-PDB-7EDJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7EDJ", "doi": "10.1038/s41594-021-00652-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EDH", "evidence_id": "EV-PDB-7EDH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7EDH", "doi": "10.1038/s41594-021-00652-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EDH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), one RBD-up conformation 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EDG", "evidence_id": "EV-PDB-7EDG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7EDG", "doi": "10.1038/s41594-021-00652-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EDG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), one RBD-up conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EDF", "evidence_id": "EV-PDB-7EDF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7EDF", "doi": "10.1038/s41594-021-00652-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EDF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), one RBD-up conformation 1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7F62", "evidence_id": "EV-PDB-7F62-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7F62", "doi": "10.1371/journal.ppat.1009704", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7F62"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody chAb-25 (Focused refinement of S-RBD and chAb-25 region)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JX3", "evidence_id": "EV-PDB-7JX3-7", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "7JX3", "doi": "10.1016/j.cell.2020.09.037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JX3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JZN", "evidence_id": "EV-PDB-7JZN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7JZN", "doi": "10.1126/science.abd9909", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JZN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with LCB3 (2RBDs open)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K43", "evidence_id": "EV-PDB-7K43-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7K43", "doi": "10.1126/science.abe3354", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K43"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the S2M11 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K45", "evidence_id": "EV-PDB-7K45-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7K45", "doi": "10.1126/science.abe3354", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K45"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K4N", "evidence_id": "EV-PDB-7K4N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7K4N", "doi": "10.1126/science.abe3354", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K4N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8M", "evidence_id": "EV-PDB-7K8M-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7K8M", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C102"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8T", "evidence_id": "EV-PDB-7K8T-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7K8T", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8U", "evidence_id": "EV-PDB-7K8U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7K8U", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8V", "evidence_id": "EV-PDB-7K8V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7K8V", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8X", "evidence_id": "EV-PDB-7K8X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7K8X", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8Y", "evidence_id": "EV-PDB-7K8Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7K8Y", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8Z", "evidence_id": "EV-PDB-7K8Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7K8Z", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C135"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K90", "evidence_id": "EV-PDB-7K90-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7K90", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K90"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K9H", "evidence_id": "EV-PDB-7K9H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7K9H", "doi": "10.1016/j.celrep.2021.109881", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K9I", "evidence_id": "EV-PDB-7K9I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7K9I", "doi": "10.1016/j.celrep.2021.109881", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K9I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2B04 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K9J", "evidence_id": "EV-PDB-7K9J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7K9J", "doi": "10.1016/j.celrep.2021.109881", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K9Z", "evidence_id": "EV-PDB-7K9Z-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "7K9Z", "doi": "10.1038/s41467-021-23825-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K9Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KDH", "evidence_id": "EV-PDB-7KDH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "7KDH", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KDH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KDI", "evidence_id": "EV-PDB-7KDI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "7KDI", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KDI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KDJ", "evidence_id": "EV-PDB-7KDJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "7KDJ", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KDK", "evidence_id": "EV-PDB-7KDK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7KDK", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KDK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KDL", "evidence_id": "EV-PDB-7KDL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "7KDL", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KDL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KE4", "evidence_id": "EV-PDB-7KE4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.21}, "provenance": {"deposit_id": "7KE4", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KE4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-class)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KE6", "evidence_id": "EV-PDB-7KE6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7KE6", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KE6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KE7", "evidence_id": "EV-PDB-7KE7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "7KE7", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 3-RBD-down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-Classification)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KE8", "evidence_id": "EV-PDB-7KE8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "7KE8", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KE9", "evidence_id": "EV-PDB-7KE9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "7KE9", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KE9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KEA", "evidence_id": "EV-PDB-7KEA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "7KEA", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub classification)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KEB", "evidence_id": "EV-PDB-7KEB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "7KEB", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 1RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KEC", "evidence_id": "EV-PDB-7KEC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "7KEC", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-Classification)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KFW", "evidence_id": "EV-PDB-7KFW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.792}, "provenance": {"deposit_id": "7KFW", "doi": "10.1101/2020.11.13.381533", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KFW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KFY", "evidence_id": "EV-PDB-7KFY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.157}, "provenance": {"deposit_id": "7KFY", "doi": "10.1101/2020.11.13.381533", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KFY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KGJ", "evidence_id": "EV-PDB-7KGJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7KGJ", "doi": "10.1016/j.jbc.2021.101202", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KGJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of synthetic nanobody (Sb45) complexes with SARS-CoV-2 receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KGK", "evidence_id": "EV-PDB-7KGK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7KGK", "doi": "10.1016/j.jbc.2021.101202", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KGK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of synthetic nanobody (Sb16) complexes with SARS-CoV-2 receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KJ2", "evidence_id": "EV-PDB-7KJ2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7KJ2", "doi": "10.1038/s41594-020-00549-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KJ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with one ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KJ3", "evidence_id": "EV-PDB-7KJ3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7KJ3", "doi": "10.1038/s41594-020-00549-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KJ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with two ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KJ4", "evidence_id": "EV-PDB-7KJ4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7KJ4", "doi": "10.1038/s41594-020-00549-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KJ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein with three ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KJ5", "evidence_id": "EV-PDB-7KJ5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7KJ5", "doi": "10.1038/s41594-020-00549-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KJ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Glycoprotein, prefusion with one RBD up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KKK", "evidence_id": "EV-PDB-7KKK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "7KKK", "doi": "10.1126/science.abe3255", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KKK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KL9", "evidence_id": "EV-PDB-7KL9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7KL9", "doi": "10.1126/science.abe0075", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KL9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the ACE2 protein decoy, CTC-445.2 (State 4)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KKL", "evidence_id": "EV-PDB-7KKL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7KKL", "doi": "10.1126/science.abe3255", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KKL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with neutralizing nanobody mNb6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KFX", "evidence_id": "EV-PDB-7KFX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.226}, "provenance": {"deposit_id": "7KFX", "doi": "10.1101/2020.11.13.381533", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KFX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-C2 Fab)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KFV", "evidence_id": "EV-PDB-7KFV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.102}, "provenance": {"deposit_id": "7KFV", "doi": "10.1101/2020.11.13.381533", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KFV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KDG", "evidence_id": "EV-PDB-7KDG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "7KDG", "doi": "10.1016/j.celrep.2020.108630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KDG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K9K", "evidence_id": "EV-PDB-7K9K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7K9K", "doi": "10.1016/j.celrep.2021.109881", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K9K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2H04 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8W", "evidence_id": "EV-PDB-7K8W-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7K8W", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7K8S", "evidence_id": "EV-PDB-7K8S-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7K8S", "doi": "10.1038/s41586-020-2852-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7K8S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JZU", "evidence_id": "EV-PDB-7JZU-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7JZU", "doi": "10.1126/science.abd9909", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JZU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with LCB1 (local refinement of the RBD and LCB1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7JZL", "evidence_id": "EV-PDB-7JZL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7JZL", "doi": "10.1126/science.abd9909", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7JZL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with LCB1 (2RBDs open)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KML", "evidence_id": "EV-PDB-7KML-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7KML", "doi": "10.1016/j.jmb.2021.167177", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KML"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, three RBDs bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KNE", "evidence_id": "EV-PDB-7KNE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "7KNE", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KNE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "NAG", "PG4", "PG5", "PGE", "SO4", "ZN", "branched: alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R,S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L0N", "evidence_id": "EV-PDB-7L0N-6", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "7L0N", "doi": "10.1016/j.cell.2021.01.037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L0N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "CAC", "NAG", "PGE", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L2C", "evidence_id": "EV-PDB-7L2C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65}, "provenance": {"deposit_id": "7L2C", "doi": "10.1016/j.chom.2021.03.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L2C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L2F", "evidence_id": "EV-PDB-7L2F-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7L2F", "doi": "10.1016/j.chom.2021.03.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L2F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NTD-directed neutralizing antibody 5-24 in complex with prefusion SARS-CoV-2 spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LAA", "evidence_id": "EV-PDB-7LAA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "7LAA", "doi": "10.1016/j.cell.2021.06.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1041"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L7K", "evidence_id": "EV-PDB-7L7K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7L7K", "doi": "10.1038/s41586-021-03275-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L7K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of protein encoded by vaccine candidate BNT162b2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein, Envelope glycoprotein fusion (chains E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L7F", "evidence_id": "EV-PDB-7L7F-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7L7F", "doi": "10.1038/s41586-021-03275-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L7F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human ACE2 receptor bound to protein encoded by vaccine candidate BNT162b1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains G,K,S,b)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L7E", "evidence_id": "EV-PDB-7L7E-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7L7E", "doi": "10.1038/s41564-021-00972-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L7E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibodies AZD8895 and AZD1061"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L7D", "evidence_id": "EV-PDB-7L7D-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7L7D", "doi": "10.1038/s41564-021-00972-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L7D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibody AZD8895"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L5B", "evidence_id": "EV-PDB-7L5B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "7L5B", "doi": "10.1016/j.celrep.2021.108950", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L5B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystallographic structure of neutralizing antibody 2-15 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L58", "evidence_id": "EV-PDB-7L58-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.07}, "provenance": {"deposit_id": "7L58", "doi": "10.1016/j.celrep.2021.108950", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L58"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab H4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L57", "evidence_id": "EV-PDB-7L57-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.87}, "provenance": {"deposit_id": "7L57", "doi": "10.1016/j.celrep.2021.108950", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L57"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-15"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L56", "evidence_id": "EV-PDB-7L56-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7L56", "doi": "10.1016/j.celrep.2021.108950", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L56"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-43"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L4Z", "evidence_id": "EV-PDB-7L4Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.96}, "provenance": {"deposit_id": "7L4Z", "doi": "10.1021/acscentsci.0c01708", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L4Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 spike RBD in complex with cyclic peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L3N", "evidence_id": "EV-PDB-7L3N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "7L3N", "doi": "10.1101/2020.09.30.318972", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L3N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV 2 Spike Protein bound to LY-CoV555"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L2E", "evidence_id": "EV-PDB-7L2E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "7L2E", "doi": "10.1016/j.chom.2021.03.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L2E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L2D", "evidence_id": "EV-PDB-7L2D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "7L2D", "doi": "10.1016/j.chom.2021.03.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L2D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NTD-directed neutralizing antibody 1-87 in complex with prefusion SARS-CoV-2 spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L09", "evidence_id": "EV-PDB-7L09-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7L09", "doi": "10.1016/j.cell.2021.04.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L09"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound domain-swapped antibody 2G12 from masked 3D refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L06", "evidence_id": "EV-PDB-7L06-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7L06", "doi": "10.1016/j.cell.2021.04.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L06"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L02", "evidence_id": "EV-PDB-7L02-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7L02", "doi": "10.1016/j.cell.2021.04.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L02"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KZB", "evidence_id": "EV-PDB-7KZB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "7KZB", "doi": "10.1080/19420862.2021.1922134", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KZB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KXK", "evidence_id": "EV-PDB-7KXK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.0}, "provenance": {"deposit_id": "7KXK", "doi": "10.1016/j.jmb.2021.167177", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KXK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with Fab 15033-7, 2-\"up\"-1-\"down\" conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KXJ", "evidence_id": "EV-PDB-7KXJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.4}, "provenance": {"deposit_id": "7KXJ", "doi": "10.1016/j.jmb.2021.167177", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KXJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with Fab 15033-7, 3-\"up\", asymmetric"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KSG", "evidence_id": "EV-PDB-7KSG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "7KSG", "doi": "10.1126/science.abe6230", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KSG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with nanobodies E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KS9", "evidence_id": "EV-PDB-7KS9-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.75}, "provenance": {"deposit_id": "7KS9", "doi": "10.1016/j.celrep.2021.109771", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KS9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of prefusion SARS-CoV-2 spike glycoprotein in complex with 910-30 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KRS", "evidence_id": "EV-PDB-7KRS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7KRS", "doi": "10.1126/science.abf2303", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KRS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural impact on SARS-CoV-2 spike protein by D614G substitution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KN6", "evidence_id": "EV-PDB-7KN6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "7KN6", "doi": "10.1126/science.abe6230", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KN5", "evidence_id": "EV-PDB-7KN5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.87}, "provenance": {"deposit_id": "7KN5", "doi": "10.1126/science.abe6230", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KN4", "evidence_id": "EV-PDB-7KN4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7KN4", "doi": "10.1002/advs.202102181", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KN4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-E6 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "PGE", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KN3", "evidence_id": "EV-PDB-7KN3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.251}, "provenance": {"deposit_id": "7KN3", "doi": "10.1002/advs.202102181", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KN3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KMZ", "evidence_id": "EV-PDB-7KMZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.62}, "provenance": {"deposit_id": "7KMZ", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KMZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of double ACE2-bound SARS-CoV-2 trimer Spike at pH 7.4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KMS", "evidence_id": "EV-PDB-7KMS-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.64}, "provenance": {"deposit_id": "7KMS", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KMS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of triple ACE2-bound SARS-CoV-2 trimer spike at pH 7.4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KMK", "evidence_id": "EV-PDB-7KMK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7KMK", "doi": "10.1016/j.jmb.2021.167177", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KMK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, two RBDs bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LJR", "evidence_id": "EV-PDB-7LJR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.66}, "provenance": {"deposit_id": "7LJR", "doi": "10.1101/2020.12.31.424729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LJR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike Protein Trimer bound to DH1043 fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LQV", "evidence_id": "EV-PDB-7LQV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "7LQV", "doi": "10.1016/j.chom.2021.03.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LQW", "evidence_id": "EV-PDB-7LQW-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.47}, "provenance": {"deposit_id": "7LQW", "doi": "10.1016/j.chom.2021.03.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LQW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "SARS-CoV-2 spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LRT", "evidence_id": "EV-PDB-7LRT-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54}, "provenance": {"deposit_id": "7LRT", "doi": "10.1126/science.abh1766", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LRT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWK", "evidence_id": "EV-PDB-7LWK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "7LWK", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWM", "evidence_id": "EV-PDB-7LWM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "7LWM", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWN", "evidence_id": "EV-PDB-7LWN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.94}, "provenance": {"deposit_id": "7LWN", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWO", "evidence_id": "EV-PDB-7LWO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7LWO", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWP", "evidence_id": "EV-PDB-7LWP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "7LWP", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 2-RBD up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWQ", "evidence_id": "EV-PDB-7LWQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "7LWQ", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein(S-GSAS-D614G-delFV) missing the S1 subunit and SD2 subdomain of one protomer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWT", "evidence_id": "EV-PDB-7LWT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "7LWT", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWV", "evidence_id": "EV-PDB-7LWV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "7LWV", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWW", "evidence_id": "EV-PDB-7LWW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7LWW", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 1-RBD-up conformation (S-GSAS-D614G-K417N-E484K-N501Y)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LX5", "evidence_id": "EV-PDB-7LX5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "7LX5", "doi": "10.1073/pnas.2101918118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LXW", "evidence_id": "EV-PDB-7LXW-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7LXW", "doi": "10.1016/j.cell.2021.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LXW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S/S2M11/S2X333 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LXX", "evidence_id": "EV-PDB-7LXX-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7LXX", "doi": "10.1016/j.cell.2021.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LXX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S/S2M11/S2L28 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LXY", "evidence_id": "EV-PDB-7LXY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "7LXY", "doi": "10.1016/j.cell.2021.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S/S2M11/S2X333 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LXZ", "evidence_id": "EV-PDB-7LXZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7LXZ", "doi": "10.1016/j.cell.2021.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LXZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S/S2M11/S2L28 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LY0", "evidence_id": "EV-PDB-7LY0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7LY0", "doi": "10.1016/j.cell.2021.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LY0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S/S2M11/S2M28 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4", "UNX", "XYL", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.75, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LY3", "evidence_id": "EV-PDB-7LY3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7LY3", "doi": "10.1016/j.cell.2021.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LY3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 S NTD bound to S2M28 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M0J", "evidence_id": "EV-PDB-7M0J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "7M0J", "doi": "10.1101/2021.03.11.435037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M0J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer - asymmetric refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M3I", "evidence_id": "EV-PDB-7M3I-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7M3I", "doi": "10.1016/j.celrep.2021.109353", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M3I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a neutralizing antibody, CV2-75 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M42", "evidence_id": "EV-PDB-7M42-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7M42", "doi": "10.1016/j.cell.2021.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M42"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M6D", "evidence_id": "EV-PDB-7M6D-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7M6D", "doi": "10.1016/j.cell.2021.04.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M6D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike glycoprotein stem helix peptide (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M53", "evidence_id": "EV-PDB-7M53-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "7M53", "doi": "10.1038/s41594-021-00596-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M53"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "B6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LYQ", "evidence_id": "EV-PDB-7LYQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34}, "provenance": {"deposit_id": "7LYQ", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LYQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LYP", "evidence_id": "EV-PDB-7LYP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.05}, "provenance": {"deposit_id": "7LYP", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LYP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LYO", "evidence_id": "EV-PDB-7LYO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "7LYO", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LYN", "evidence_id": "EV-PDB-7LYN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "7LYN", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LYN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LYM", "evidence_id": "EV-PDB-7LYM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.57}, "provenance": {"deposit_id": "7LYM", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LYL", "evidence_id": "EV-PDB-7LYL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "7LYL", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LYL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LYK", "evidence_id": "EV-PDB-7LYK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65}, "provenance": {"deposit_id": "7LYK", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LYK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 2-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LY2", "evidence_id": "EV-PDB-7LY2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7LY2", "doi": "10.1016/j.cell.2021.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LY2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S/S2M11/S2M28 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWU", "evidence_id": "EV-PDB-7LWU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "7LWU", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWS", "evidence_id": "EV-PDB-7LWS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "7LWS", "doi": "10.1101/2021.03.11.435037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "UK (B.1.1.7) SARS-CoV-2 S-GSAS-D614G variant spike protein in the 3-RBD-down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWL", "evidence_id": "EV-PDB-7LWL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "7LWL", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWJ", "evidence_id": "EV-PDB-7LWJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7LWJ", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LWI", "evidence_id": "EV-PDB-7LWI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "7LWI", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LWI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LSS", "evidence_id": "EV-PDB-7LSS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "7LSS", "doi": "10.1016/j.str.2021.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LSS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LS9", "evidence_id": "EV-PDB-7LS9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "7LS9", "doi": "10.1016/j.str.2021.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LS9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LRS", "evidence_id": "EV-PDB-7LRS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.89}, "provenance": {"deposit_id": "7LRS", "doi": "10.1126/science.abh1766", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LRS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LQ7", "evidence_id": "EV-PDB-7LQ7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7LQ7", "doi": "10.1126/scitranslmed.abj5413", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LQ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M6F", "evidence_id": "EV-PDB-7M6F-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7M6F", "doi": "10.1016/j.cell.2021.04.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M6F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG1-22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M6H", "evidence_id": "EV-PDB-7M6H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7M6H", "doi": "10.1016/j.cell.2021.04.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M6H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG7-20"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M6I", "evidence_id": "EV-PDB-7M6I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7M6I", "doi": "10.1016/j.cell.2021.04.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M6I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG1-24"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M71", "evidence_id": "EV-PDB-7M71-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "7M71", "doi": "10.1016/j.cell.2021.04.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M71"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike:5A6 Fab complex I focused refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M7B", "evidence_id": "EV-PDB-7M7B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "7M7B", "doi": "10.1016/j.cell.2021.04.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M7B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike:Fab 3D11 complex focused refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R,S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M7W", "evidence_id": "EV-PDB-7M7W-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "7M7W", "doi": "10.1038/s41586-021-03807-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M7W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M8J", "evidence_id": "EV-PDB-7M8J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "7M8J", "doi": "10.1126/science.abg5268", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M8J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S-NTD + Fab CM25"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 peptide (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M8S", "evidence_id": "EV-PDB-7M8S-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "7M8S", "doi": "10.3390/biophysica1020015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M8S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HLA-A*02:01 in complex with KLNDLCFTNV, an 10-mer epitope from SARS-CoV-2 Spike (S386-395)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "GOL", "NA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 peptide (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M8T", "evidence_id": "EV-PDB-7M8T-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "7M8T", "doi": "10.3390/biophysica1020015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M8T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HLA-A*11:01 in complex with NSASFSTFK, an 9-mer epitope from SARS-CoV-2 spike (S370-378)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 peptide (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M8U", "evidence_id": "EV-PDB-7M8U-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "7M8U", "doi": "10.3390/biophysica1020015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M8U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HLA-B*35:01 in complex with IPFAMQMAY, an 9-mer epitope from SARS-CoV-2 spike (S896-904)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MDW", "evidence_id": "EV-PDB-7MDW-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.58}, "provenance": {"deposit_id": "7MDW", "doi": "10.1038/s41467-021-24963-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MDW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb105"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MJK", "evidence_id": "EV-PDB-7MJK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.73}, "provenance": {"deposit_id": "7MJK", "doi": "10.1371/journal.pbio.3001237", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MJK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MJM", "evidence_id": "EV-PDB-7MJM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "7MJM", "doi": "10.1371/journal.pbio.3001237", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MJM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MJN", "evidence_id": "EV-PDB-7MJN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7MJN", "doi": "10.1371/journal.pbio.3001237", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MJN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MLZ", "evidence_id": "EV-PDB-7MLZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.71}, "provenance": {"deposit_id": "7MLZ", "doi": "10.1126/science.abh1766", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MMO", "evidence_id": "EV-PDB-7MMO-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.427}, "provenance": {"deposit_id": "7MMO", "doi": "10.1101/2021.04.30.442182", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MMO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LY-CoV1404 neutralizing antibody against SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "SCN", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MSQ", "evidence_id": "EV-PDB-7MSQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.29}, "provenance": {"deposit_id": "7MSQ", "doi": "10.1016/j.immuni.2021.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MSQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MTC", "evidence_id": "EV-PDB-7MTC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7MTC", "doi": "10.1016/j.jbc.2021.101127", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MTC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MTD", "evidence_id": "EV-PDB-7MTD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7MTD", "doi": "10.1016/j.jbc.2021.101127", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of aged SARS-CoV-2 S2P spike at pH 7.4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MTE", "evidence_id": "EV-PDB-7MTE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7MTE", "doi": "10.1016/j.jbc.2021.101127", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MTE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 S2P spike at pH 7.4 refolded by low-pH treatment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MW2", "evidence_id": "EV-PDB-7MW2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "7MW2", "doi": "10.1038/s41467-022-29288-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MW2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike trimer with all RBDs down in complex with the Fab fragment of human neutralizing antibody clone 6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MW3", "evidence_id": "EV-PDB-7MW3-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15}, "provenance": {"deposit_id": "7MW3", "doi": "10.1038/s41467-022-29288-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MW3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody clone 6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MW4", "evidence_id": "EV-PDB-7MW4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "7MW4", "doi": "10.1038/s41467-022-29288-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MW4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody clone 6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MW5", "evidence_id": "EV-PDB-7MW5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "7MW5", "doi": "10.1038/s41467-022-29288-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MW5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody clone 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)][beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MXP", "evidence_id": "EV-PDB-7MXP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.46}, "provenance": {"deposit_id": "7MXP", "doi": "10.1002/aic.17440", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MXP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MY2", "evidence_id": "EV-PDB-7MY2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "7MY2", "doi": "10.1038/s41586-021-03676-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MY2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of neutralizing nanobody Nb30 in complex with SARS-CoV2 spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MY3", "evidence_id": "EV-PDB-7MY3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7MY3", "doi": "10.1038/s41586-021-03676-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MY3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of neutralizing nanobody Nb12 in complex with SARS-CoV2 spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 31.85}, "construct": {"description": "Spike protein S2 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MY8", "evidence_id": "EV-PDB-7MY8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7MY8", "doi": "10.1021/jacs.1c05435", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MY8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Fusion Peptide of SARS-CoV-2 Spike Rearranges into a Wedge Inserted in Bilayered Micelles"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZF", "evidence_id": "EV-PDB-7MZF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.493}, "provenance": {"deposit_id": "7MZF", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab PDI 37"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZG", "evidence_id": "EV-PDB-7MZG-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "7MZG", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab PDI 42"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZH", "evidence_id": "EV-PDB-7MZH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "7MZH", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab WCSL 119"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PG4", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZI", "evidence_id": "EV-PDB-7MZI-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "7MZI", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab WCSL 129"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZJ", "evidence_id": "EV-PDB-7MZJ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7MZJ", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 93"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MW6", "evidence_id": "EV-PDB-7MW6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "7MW6", "doi": "10.1038/s41467-022-29288-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MW6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike trimer with three RBDs up in complex with the Fab fragment of human neutralizing antibody clone 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MKL", "evidence_id": "EV-PDB-7MKL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7MKL", "doi": "10.1016/j.immuni.2021.08.016", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MKL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-38 (three down conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MJJ", "evidence_id": "EV-PDB-7MJJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "7MJJ", "doi": "10.1371/journal.pbio.3001237", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MJJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MEJ", "evidence_id": "EV-PDB-7MEJ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "7MEJ", "doi": "10.1038/s41467-021-24963-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MEJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb36"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M8K", "evidence_id": "EV-PDB-7M8K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7M8K", "doi": "10.1016/j.chom.2021.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M8K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Brazil (P.1) SARS-CoV-2 spike glycoprotein variant in the prefusion state (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M6G", "evidence_id": "EV-PDB-7M6G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7M6G", "doi": "10.1016/j.cell.2021.04.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M6G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG7-15"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7M6E", "evidence_id": "EV-PDB-7M6E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7M6E", "doi": "10.1016/j.cell.2021.04.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7M6E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG10-19"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "GOL", "MPD", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZK", "evidence_id": "EV-PDB-7MZK-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "7MZK", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 96"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZL", "evidence_id": "EV-PDB-7MZL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7MZL", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab PDI 210"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IPA", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZM", "evidence_id": "EV-PDB-7MZM-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7MZM", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab PDI 215"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MZN", "evidence_id": "EV-PDB-7MZN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7MZN", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MZN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 receptor binding domain bound to Fab PDI 231"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N0G", "evidence_id": "EV-PDB-7N0G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "7N0G", "doi": "10.1016/j.jbc.2021.101202", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N0G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEm structure of SARS-CoV-2 spike protein (S-6P, 1-up) in complex with sybodies (Sb45)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N0H", "evidence_id": "EV-PDB-7N0H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34}, "provenance": {"deposit_id": "7N0H", "doi": "10.1016/j.jbc.2021.101202", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N0H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS-CoV-2 spike protein (S-6P, 2-up) in complex with sybodies (Sb45)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1A", "evidence_id": "EV-PDB-7N1A-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.065}, "provenance": {"deposit_id": "7N1A", "doi": "10.1038/s41467-021-27669-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 YLQ peptide binds to HLA-A2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1B", "evidence_id": "EV-PDB-7N1B-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "7N1B", "doi": "10.1038/s41467-021-27669-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 RLQ peptide binds to HLA-A2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1E", "evidence_id": "EV-PDB-7N1E-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7N1E", "doi": "10.1038/s41467-021-27669-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 RLQ peptide-specific TCR pRLQ3 binds to RLQ-HLA-A2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N3I", "evidence_id": "EV-PDB-7N3I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.03}, "provenance": {"deposit_id": "7N3I", "doi": "10.1016/j.immuni.2021.07.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N3I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment C098"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N5H", "evidence_id": "EV-PDB-7N5H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7N5H", "doi": "10.1080/22221751.2021.2011623", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N5H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of broadly neutralizing antibody 2-36 in complex with prefusion SARS-CoV-2 spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N62", "evidence_id": "EV-PDB-7N62-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7N62", "doi": "10.1101/2021.03.10.434840", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N62"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (2P) in complex with C12C9 Fab (NTD local reconstruction)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N64", "evidence_id": "EV-PDB-7N64-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7N64", "doi": "10.1101/2021.03.10.434840", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N64"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (2P) in complex with G32R7 Fab (RBD and NTD local reconstruction)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N8I", "evidence_id": "EV-PDB-7N8I-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7N8I", "doi": "10.1126/science.abi7994", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N8I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 (Local Refinement of the NTD/S2L20)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N9A", "evidence_id": "EV-PDB-7N9A-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7N9A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N9A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS RBD with NB21"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N9B", "evidence_id": "EV-PDB-7N9B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7N9B", "doi": "10.1038/s41467-021-24963-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N9B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB21"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N9E", "evidence_id": "EV-PDB-7N9E-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "7N9E", "doi": "10.1038/s41467-021-24963-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N9E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N9T", "evidence_id": "EV-PDB-7N9T-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "7N9T", "doi": "10.1038/s41467-021-24963-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N9T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS-CoV-2 Spike in complex with Nb17"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ND3", "evidence_id": "EV-PDB-7ND3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7ND3", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ND3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-40 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ND5", "evidence_id": "EV-PDB-7ND5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7ND5", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ND5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-150 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ND6", "evidence_id": "EV-PDB-7ND6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.3}, "provenance": {"deposit_id": "7ND6", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ND6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-40 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ND7", "evidence_id": "EV-PDB-7ND7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7ND7", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ND7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-316 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ND8", "evidence_id": "EV-PDB-7ND8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7ND8", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ND8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-384 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ND9", "evidence_id": "EV-PDB-7ND9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7ND9", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ND9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein (one RBD up) in complex with COVOX-253H55L Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NDA", "evidence_id": "EV-PDB-7NDA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7NDA", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NDA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein (all RBD down) in complex with COVOX-253H55L Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NDB", "evidence_id": "EV-PDB-7NDB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "7NDB", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NDB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-253H165L Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NDC", "evidence_id": "EV-PDB-7NDC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7NDC", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NDC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein (all RBD down) in complex with COVOX-159"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NDD", "evidence_id": "EV-PDB-7NDD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7NDD", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NDD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein (one RBD up) in complex with COVOX-159"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Surface glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NEG", "evidence_id": "EV-PDB-7NEG-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.19}, "provenance": {"deposit_id": "7NEG", "doi": "10.1016/j.cell.2021.02.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NEG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N501Y mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-269 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NO3", "PEG", "SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NEH", "evidence_id": "EV-PDB-7NEH-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.77}, "provenance": {"deposit_id": "7NEH", "doi": "10.1016/j.cell.2021.02.033", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NEH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-269 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "PEG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains AAA)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NKT", "evidence_id": "EV-PDB-7NKT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7NKT", "doi": "10.15252/embr.202052325", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NKT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RBD domain of SARS-CoV2 in complex with neutralizing nanobody NM1226"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NLL", "evidence_id": "EV-PDB-7NLL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "7NLL", "doi": "10.1038/s41467-021-27610-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NLL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike RBD (dimer) in complex with two Fu2 nanobodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ND4", "evidence_id": "EV-PDB-7ND4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7ND4", "doi": "10.1016/j.cell.2021.02.032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ND4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-88 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NAB", "evidence_id": "EV-PDB-7NAB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "7NAB", "doi": "10.1016/j.celrep.2021.110210", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NAB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human neutralizing mAb CV3-25 binding to SARS-CoV-2 S MPER peptide 1140-1165"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N9C", "evidence_id": "EV-PDB-7N9C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.71}, "provenance": {"deposit_id": "7N9C", "doi": "10.1038/s41467-021-24963-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N9C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,F,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N8H", "evidence_id": "EV-PDB-7N8H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7N8H", "doi": "10.1126/science.abi7994", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N8H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N4M", "evidence_id": "EV-PDB-7N4M-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.79}, "provenance": {"deposit_id": "7N4M", "doi": "10.1038/s41590-021-01068-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N4M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2151."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1X", "evidence_id": "EV-PDB-7N1X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7N1X", "doi": "10.1126/science.abi9745", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1W", "evidence_id": "EV-PDB-7N1W-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "7N1W", "doi": "10.1126/science.abi9745", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1U", "evidence_id": "EV-PDB-7N1U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7N1U", "doi": "10.1126/science.abi9745", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1T", "evidence_id": "EV-PDB-7N1T-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "7N1T", "doi": "10.1126/science.abi9745", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N1F", "evidence_id": "EV-PDB-7N1F-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.393}, "provenance": {"deposit_id": "7N1F", "doi": "10.1038/s41467-021-27669-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N1F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 binds to YLQ-HLA-A2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NP1", "evidence_id": "EV-PDB-7NP1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7NP1", "doi": "10.3389/fimmu.2021.678570", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NP1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the SARS-CoV-2 Receptor Binding Domain in Complex with Antibody ION-360"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NS6", "evidence_id": "EV-PDB-7NS6-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "7NS6", "doi": "10.1038/s41467-021-27610-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NS6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (dimers) in complex with six Fu2 nanobodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NT9", "evidence_id": "EV-PDB-7NT9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "7NT9", "doi": "10.1126/sciadv.abg7607", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NT9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (closed conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NX6", "evidence_id": "EV-PDB-7NX6-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "7NX6", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NX6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "CL", "GOL", "NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NX7", "evidence_id": "EV-PDB-7NX7-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7NX7", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the K417N mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "CL", "GOL", "NAG", "PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NX8", "evidence_id": "EV-PDB-7NX8-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "7NX8", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NX8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the K417T mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NX9", "evidence_id": "EV-PDB-7NX9-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7NX9", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N501Y mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG", "PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NXA", "evidence_id": "EV-PDB-7NXA-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7NXA", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NXA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 B.1.351 variant Spike glycoprotein in complex with COVOX-222 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG", "PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NXB", "evidence_id": "EV-PDB-7NXB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67}, "provenance": {"deposit_id": "7NXB", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NXB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 P.1 variant Spike glycoprotein in complex with COVOX-222 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAN", "evidence_id": "EV-PDB-7OAN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7OAN", "doi": "10.1038/s41467-021-25480-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Nanobody C5 bound to Spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAO", "evidence_id": "EV-PDB-7OAO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "7OAO", "doi": "10.1038/s41467-021-25480-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody C5 bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "CL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAP", "evidence_id": "EV-PDB-7OAP-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.901}, "provenance": {"deposit_id": "7OAP", "doi": "10.1038/s41467-021-25480-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody H3 AND C1 bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "CL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAQ", "evidence_id": "EV-PDB-7OAQ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "7OAQ", "doi": "10.1038/s41467-021-25480-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody H3 AND C1 bound to RBD with Kent mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains AAA,EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAU", "evidence_id": "EV-PDB-7OAU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "7OAU", "doi": "10.1038/s41467-021-25480-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody C5 bound to Kent variant RBD (N501Y)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains AAA,CCC,EEE,GGG,III,KKK)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OAY", "evidence_id": "EV-PDB-7OAY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.34}, "provenance": {"deposit_id": "7OAY", "doi": "10.1038/s41467-021-25480-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OAY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody F2 bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DMX", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OLZ", "evidence_id": "EV-PDB-7OLZ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "7OLZ", "doi": "10.15252/embj.2021107985", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD with neutralizing-VHHs Re5D06 and Re9F06"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "PG4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OR9", "evidence_id": "EV-PDB-7OR9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.34}, "provenance": {"deposit_id": "7OR9", "doi": "10.1016/j.cell.2021.06.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OR9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and COVOX-278 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ORA", "evidence_id": "EV-PDB-7ORA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7ORA", "doi": "10.1016/j.cell.2021.06.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ORA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the T478K mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-45 and COVOX-253 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P19", "evidence_id": "EV-PDB-7P19-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7P19", "doi": "10.1107/S2059798322007677", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P19"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD Q498Y complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IOD", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TYR-LEU-GLN-LEU-ARG-THR-PHE-LEU-LEU (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P3E", "evidence_id": "EV-PDB-7P3E-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "7P3E", "doi": "10.1016/j.cell.2022.07.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P3E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MHC I A02 Allele presenting YLQLRTFLL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 2.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P5G", "evidence_id": "EV-PDB-7P5G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7P5G", "doi": "10.1016/j.heliyon.2022.e11568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P5G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of a peptide deriving from SARS-CoV-2 S RBD 482-506 fragment in HFIP/H2O"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P77", "evidence_id": "EV-PDB-7P77-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "7P77", "doi": "10.15252/embr.202154199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P77"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 3up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P78", "evidence_id": "EV-PDB-7P78-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "7P78", "doi": "10.15252/embr.202154199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P78"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 1up/1up-out/1down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P79", "evidence_id": "EV-PDB-7P79-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7P79", "doi": "10.15252/embr.202154199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P79"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with sybodyb#15 in a 1up/1up-out/1down conformation."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P7A", "evidence_id": "EV-PDB-7P7A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.76}, "provenance": {"deposit_id": "7P7A", "doi": "10.15252/embr.202154199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P7A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with sybody#68 in a 2up/1flexible conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P7B", "evidence_id": "EV-PDB-7P7B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "7P7B", "doi": "10.15252/embr.202154199", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P7B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with sybody no68 in a 1up/2down conformation"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Surface glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PHG", "evidence_id": "EV-PDB-7PHG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7PHG", "doi": "10.1016/j.celrep.2021.109814", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PHG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "MaP OF P5C3RBD Interface"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PQY", "evidence_id": "EV-PDB-7PQY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7PQY", "doi": "10.7150/thno.65563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PQY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "NO3", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PR0", "evidence_id": "EV-PDB-7PR0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "7PR0", "doi": "10.7150/thno.65563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PR0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FD-5D Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PRY", "evidence_id": "EV-PDB-7PRY-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7PRY", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PRY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with COVOX-45 and beta-6 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PRZ", "evidence_id": "EV-PDB-7PRZ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7PRZ", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PRZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with beta-22 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PS0", "evidence_id": "EV-PDB-7PS0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "7PS0", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PS0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with beta-24 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "IOD", "NAG", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PS1", "evidence_id": "EV-PDB-7PS1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7PS1", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PS1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-27 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PEG", "SO4", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PS2", "evidence_id": "EV-PDB-7PS2-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "7PS2", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PS2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-29 and Beta-53 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PS4", "evidence_id": "EV-PDB-7PS4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "7PS4", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PS4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-38"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PS5", "evidence_id": "EV-PDB-7PS5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7PS5", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PS5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-47 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PQZ", "evidence_id": "EV-PDB-7PQZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7PQZ", "doi": "10.7150/thno.65563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PQZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A and FD-11A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 2.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P5S", "evidence_id": "EV-PDB-7P5S-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7P5S", "doi": "10.1016/j.heliyon.2022.e11568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P5S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of a peptide deriving from SARS-CoV-2 Lineages P.1 and B.1.351 S RBD 482-506 fragment in HFIP/H2O"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 2.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P5Q", "evidence_id": "EV-PDB-7P5Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7P5Q", "doi": "10.1016/j.heliyon.2022.e11568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P5Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of a peptide deriving from SARS-CoV-2 Lineage B.1.1.7 S RBD 482-506 fragment in HFIP/H2O"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P40", "evidence_id": "EV-PDB-7P40-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7P40", "doi": "10.1016/j.celrep.2021.109814", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P40"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "P5C3 is a potent fab neutralizer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CA", "EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P3D", "evidence_id": "EV-PDB-7P3D-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.67}, "provenance": {"deposit_id": "7P3D", "doi": "10.1016/j.cell.2022.07.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P3D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "MHC I A02 Allele presenting YLQPRTFLL"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OWX", "evidence_id": "EV-PDB-7OWX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.929}, "provenance": {"deposit_id": "7OWX", "doi": "10.1096/fj.202101670R", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OWX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of coiled-coil tetramer from SARS-CoV-2 spike stalk region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BTB", "CL", "GOL", "PEG", "PO4", "TRS", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R,X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ORB", "evidence_id": "EV-PDB-7ORB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7ORB", "doi": "10.1016/j.cell.2021.06.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ORB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the L452R mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-75 and COVOX-253 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EIC", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ODL", "evidence_id": "EV-PDB-7ODL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "7ODL", "doi": "10.1038/s41467-021-27881-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ODL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C1 symmetry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EIC", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OD3", "evidence_id": "EV-PDB-7OD3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7OD3", "doi": "10.1038/s41467-021-27881-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OD3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C3 symmetry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NXC", "evidence_id": "EV-PDB-7NXC-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7NXC", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 P.1 variant Spike glycoprotein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NTC", "evidence_id": "EV-PDB-7NTC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7NTC", "doi": "10.1126/sciadv.abg7607", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NTC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trimeric SARS-CoV-2 spike ectodomain bound to P008_056 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NTA", "evidence_id": "EV-PDB-7NTA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7NTA", "doi": "10.1126/sciadv.abg7607", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NTA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (one RBD erect)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R4Q", "evidence_id": "EV-PDB-7R4Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7R4Q", "doi": "10.3389/fimmu.2022.863831", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R4Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The SARS-CoV-2 spike in complex with the 1.29 neutralizing nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R8L", "evidence_id": "EV-PDB-7R8L-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7R8L", "doi": "10.1016/j.immuni.2021.07.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R8L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R7N", "evidence_id": "EV-PDB-7R7N-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "7R7N", "doi": "10.1038/s41586-021-03807-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R7N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the S2D106 neutralizing antibody Fab fragment (local refinement of the RBD and S2D106)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R6X", "evidence_id": "EV-PDB-7R6X-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "7R6X", "doi": "10.1038/s41586-021-03807-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R6X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2E12 Fab, S309 Fab, and S304 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "POL", "SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R6W", "evidence_id": "EV-PDB-7R6W-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.83}, "provenance": {"deposit_id": "7R6W", "doi": "10.1038/s41586-021-03807-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R6W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2X35 Fab and S309 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R4R", "evidence_id": "EV-PDB-7R4R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7R4R", "doi": "10.3389/fimmu.2022.863831", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R4R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The SARS-CoV-2 spike in complex with the 1.10 neutralizing nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R4I", "evidence_id": "EV-PDB-7R4I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7R4I", "doi": "10.3389/fimmu.2022.863831", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R4I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The SARS-CoV-2 spike in complex with the 2.15 neutralizing nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R40", "evidence_id": "EV-PDB-7R40-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7R40", "doi": "10.1126/sciimmunol.abp9312", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R40"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R1B", "evidence_id": "EV-PDB-7R1B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7R1B", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R1B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Variant SARS-CoV-2 Spike with 1 Erect RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R1A", "evidence_id": "EV-PDB-7R1A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7R1A", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R1A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Furin Cleaved Alpha Variant SARS-CoV-2 Spike in complex with 3 ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R19", "evidence_id": "EV-PDB-7R19-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7R19", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R19"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Variant SARS-CoV-2 Spike with 2 Erect RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R18", "evidence_id": "EV-PDB-7R18-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7R18", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R18"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Mink Variant SARS-CoV-2 Spike in Closed conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R17", "evidence_id": "EV-PDB-7R17-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7R17", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R17"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta Variant SARS-CoV-2 Spike with 2 Erect RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R16", "evidence_id": "EV-PDB-7R16-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7R16", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R16"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta Variant SARS-CoV-2 Spike with 1 Erect RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R15", "evidence_id": "EV-PDB-7R15-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7R15", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R15"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha Variant SARS-CoV-2 Spike with 2 Erect RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R14", "evidence_id": "EV-PDB-7R14-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7R14", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha Variant SARS-CoV-2 Spike with 1 Erect RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R13", "evidence_id": "EV-PDB-7R13-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7R13", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R13"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha Variant SARS-CoV-2 Spike in Closed conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R12", "evidence_id": "EV-PDB-7R12-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7R12", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R12"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of Mink Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R11", "evidence_id": "EV-PDB-7R11-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7R11", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R11"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of Beta Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R10", "evidence_id": "EV-PDB-7R10-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7R10", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R10"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R0Z", "evidence_id": "EV-PDB-7R0Z-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7R0Z", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R0Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QUS", "evidence_id": "EV-PDB-7QUS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "7QUS", "doi": "10.1126/science.abm3125", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QUS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike, C3 symmetry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Envelope glycoprotein (chains A,D,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QTI", "evidence_id": "EV-PDB-7QTI-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "7QTI", "doi": "10.1038/s41564-022-01198-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S Omicron Spike B.1.1.529 - 3-P2G3 and 1-P5C3 Fabs (Global)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,SARS-CoV-2 S Omicron Spike B.1.1.529 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QO9", "evidence_id": "EV-PDB-7QO9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88}, "provenance": {"deposit_id": "7QO9", "doi": "10.1101/2021.12.27.474250", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S Omicron Spike B.1.1.529 - RBD and NTD (Local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Surface glycoprotein,Fibritin,SARS-CoV-2 S Omicron Spike B.1.1.529 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QO7", "evidence_id": "EV-PDB-7QO7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "7QO7", "doi": "10.1101/2021.12.27.474250", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QO7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S Omicron Spike B.1.1.529"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NA", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Surface glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QNY", "evidence_id": "EV-PDB-7QNY-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "7QNY", "doi": "10.1016/j.cell.2021.12.046", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QNY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with COVOX-58 and COVOX-158 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Surface glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QNX", "evidence_id": "EV-PDB-7QNX-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "7QNX", "doi": "10.1016/j.cell.2021.12.046", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QNX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with Beta-55 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CL", "GOL", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Surface glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QNW", "evidence_id": "EV-PDB-7QNW-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7QNW", "doi": "10.1016/j.cell.2021.12.046", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QNW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The receptor binding domain of SARS-CoV-2 Omicron variant spike glycoprotein in complex with Beta-55 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike protein S1 (chains A,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QF1", "evidence_id": "EV-PDB-7QF1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7QF1", "doi": "10.1084/jem.20220638", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QF1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.6264"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QF0", "evidence_id": "EV-PDB-7QF0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7QF0", "doi": "10.1084/jem.20220638", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QF0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QEZ", "evidence_id": "EV-PDB-7QEZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "7QEZ", "doi": "10.1084/jem.20220638", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QEZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QDH", "evidence_id": "EV-PDB-7QDH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7QDH", "doi": "10.1371/journal.ppat.1010631", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QDH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein S:D614G mutant 1-up"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QDG", "evidence_id": "EV-PDB-7QDG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7QDG", "doi": "10.1371/journal.ppat.1010631", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QDG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein S:A222V + S:D614G mutant 1-up"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q9P", "evidence_id": "EV-PDB-7Q9P-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "7Q9P", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta-06 fab in complex with SARS-CoV-2 beta-Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q9M", "evidence_id": "EV-PDB-7Q9M-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7Q9M", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q9M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta-53 fab in complex with SARS-CoV-2 beta-Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q9K", "evidence_id": "EV-PDB-7Q9K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "7Q9K", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q9K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta-32 fab in complex with SARS-CoV-2 beta-Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q9J", "evidence_id": "EV-PDB-7Q9J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7Q9J", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta-26 fab in complex with SARS-CoV-2 beta-Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q9I", "evidence_id": "EV-PDB-7Q9I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.9}, "provenance": {"deposit_id": "7Q9I", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q9I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta-43 fab in complex with SARS-CoV-2 beta-Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q9G", "evidence_id": "EV-PDB-7Q9G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7Q9G", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q9G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "COVOX-222 fab in complex with SARS-CoV-2 beta-Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q9F", "evidence_id": "EV-PDB-7Q9F-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7Q9F", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q9F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta-50 fab in complex with SARS-CoV-2 beta-Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q6E", "evidence_id": "EV-PDB-7Q6E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7Q6E", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q6E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta049 fab in complex with SARS-CoV2 beta-Spike glycoprotein, The Beta mAb response underscores the antigenic distance to other SARS-CoV-2 variants"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q3R", "evidence_id": "EV-PDB-7Q3R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.92}, "provenance": {"deposit_id": "7Q3R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q3R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing nanobodies VHH-F04 and VHH-G09"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q3Q", "evidence_id": "EV-PDB-7Q3Q-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7Q3Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q3Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing nanobody VHH-12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q1Z", "evidence_id": "EV-PDB-7Q1Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7Q1Z", "doi": "10.1016/j.xcrm.2022.100528", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q1Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of formaldehyde cross-linked SARS-CoV-2 S glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "PEG", "PG4", "PO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q0I", "evidence_id": "EV-PDB-7Q0I-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "7Q0I", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q0I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N-terminal domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-43"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q0H", "evidence_id": "EV-PDB-7Q0H-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65}, "provenance": {"deposit_id": "7Q0H", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q0H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-50 and Beta-54"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "K", "TAR", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q0G", "evidence_id": "EV-PDB-7Q0G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82}, "provenance": {"deposit_id": "7Q0G", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q0G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-49 and FI-3A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Spike ectodomain,Spike protein S2' (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q0A", "evidence_id": "EV-PDB-7Q0A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8}, "provenance": {"deposit_id": "7Q0A", "doi": "10.7150/thno.65563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q0A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike ectodomain with Fab FI3A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PS7", "evidence_id": "EV-PDB-7PS7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7PS7", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PS7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-40 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "PEG", "PG0", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7PS6", "evidence_id": "EV-PDB-7PS6-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26}, "provenance": {"deposit_id": "7PS6", "doi": "10.1016/j.chom.2021.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7PS6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-44 and Beta-54 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RQ6", "evidence_id": "EV-PDB-7RQ6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.18}, "provenance": {"deposit_id": "7RQ6", "doi": "10.1016/j.celrep.2022.110368", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RQ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with non-neutralizing NTD-directed CV3-13 Fab isolated from convalescent individual"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S0B", "evidence_id": "EV-PDB-7S0B-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7S0B", "doi": "10.1016/j.celrep.2022.110348", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S0B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody N-612-056"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S4S", "evidence_id": "EV-PDB-7S4S-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "7S4S", "doi": "10.3389/fimmu.2023.1178355", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S4S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SARS-CoV-2 S receptor-binding domain (RBD) in complex CoV11 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SBO", "evidence_id": "EV-PDB-7SBO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7SBO", "doi": "10.1126/science.abl9463", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SBO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "One RBD-up 2 of pre-fusion SARS-CoV-2 Delta variant spike protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S6L", "evidence_id": "EV-PDB-7S6L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7S6L", "doi": "10.1073/pnas.2120976119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S6L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S6K", "evidence_id": "EV-PDB-7S6K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7S6K", "doi": "10.1073/pnas.2120976119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S6I", "evidence_id": "EV-PDB-7S6I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7S6I", "doi": "10.1073/pnas.2120976119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S6I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2-6P-Mut2 S protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S5R", "evidence_id": "EV-PDB-7S5R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "7S5R", "doi": "10.1126/science.abm5835", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S5R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibodies CV07-287 and COVA1-16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S5Q", "evidence_id": "EV-PDB-7S5Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88}, "provenance": {"deposit_id": "7S5Q", "doi": "10.1126/science.abm5835", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S5Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibodies CS44 and COVA1-16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S5P", "evidence_id": "EV-PDB-7S5P-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "7S5P", "doi": "10.1126/science.abm5835", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S5P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 B.1.351 variant receptor binding domain in complex with neutralizing antibody CS23"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S3N", "evidence_id": "EV-PDB-7S3N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "7S3N", "doi": "10.1016/j.celrep.2021.109929", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S3N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 S stem helix peptide bound to Fab22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S0E", "evidence_id": "EV-PDB-7S0E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.9}, "provenance": {"deposit_id": "7S0E", "doi": "10.1016/j.celrep.2022.110348", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S0E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S1 subunit in complex with antibody N-612-004"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S0D", "evidence_id": "EV-PDB-7S0D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7S0D", "doi": "10.1016/j.celrep.2022.110348", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S0D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-014"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S0C", "evidence_id": "EV-PDB-7S0C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "7S0C", "doi": "10.1016/j.celrep.2022.110348", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S0C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-017"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RZV", "evidence_id": "EV-PDB-7RZV-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.11}, "provenance": {"deposit_id": "7RZV", "doi": "10.1073/pnas.2119467119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RZV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with V1176F mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2' (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RZV", "evidence_id": "EV-PDB-7RZV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.11}, "provenance": {"deposit_id": "7RZV", "doi": "10.1073/pnas.2119467119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RZV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with V1176F mutation"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RU2", "evidence_id": "EV-PDB-7RU2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7RU2", "doi": "10.1016/j.isci.2022.104914", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RU2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2-6P-Mut7 S protein (asymmetric)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RU1", "evidence_id": "EV-PDB-7RU1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7RU1", "doi": "10.1016/j.isci.2022.104914", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RU1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2-6P-Mut7 S protein (C3 symmetry)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RTR", "evidence_id": "EV-PDB-7RTR-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7RTR", "doi": "10.3390/cells10102646", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RTR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "YLQ-SG3 TCR in complex with SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RTD", "evidence_id": "EV-PDB-7RTD-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "7RTD", "doi": "10.3390/cells10102646", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RR0", "evidence_id": "EV-PDB-7RR0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "7RR0", "doi": "10.1016/j.celrep.2021.109822", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RR0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 receptor binding domain bound to Fab PDI 222"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RPV", "evidence_id": "EV-PDB-7RPV-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54}, "provenance": {"deposit_id": "7RPV", "doi": "10.1101/2021.11.24.469776", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RPV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of affinity-enhancing and catalytically inactive ACE2 in complex with SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein stem helix peptide (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RNJ", "evidence_id": "EV-PDB-7RNJ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67}, "provenance": {"deposit_id": "7RNJ", "doi": "10.1126/science.abj3321", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RNJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "S2P6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RKV", "evidence_id": "EV-PDB-7RKV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "7RKV", "doi": "10.1016/j.celrep.2021.109760", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RKV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RKU", "evidence_id": "EV-PDB-7RKU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7RKU", "doi": "10.1016/j.celrep.2021.109760", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RKU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C022"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RBY", "evidence_id": "EV-PDB-7RBY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "7RBY", "doi": "10.1080/19420862.2022.2047144", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Nanobody nb112 and SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RBV", "evidence_id": "EV-PDB-7RBV-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7RBV", "doi": "10.1128/mbio.03580-21", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with PVI.V6-14 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RBU", "evidence_id": "EV-PDB-7RBU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7RBU", "doi": "10.1128/mbio.03580-21", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with PVI.V6-14 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "spike stem helix peptide (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RAQ", "evidence_id": "EV-PDB-7RAQ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.74}, "provenance": {"deposit_id": "7RAQ", "doi": "10.1038/s42003-022-03262-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RAQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of CV3-25 Fab bound to SARS-CoV-2 spike stem helix peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RAL", "evidence_id": "EV-PDB-7RAL-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7RAL", "doi": "10.1038/s41586-021-03817-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RAL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S bound to S2X259 Fab (local refinement of the RBD/S2X259 variable domains)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RA8", "evidence_id": "EV-PDB-7RA8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7RA8", "doi": "10.1038/s41586-021-03817-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RA8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S glycoprotein in complex with S2X259 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 34.85}, "construct": {"description": "Spike protein S2 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R95", "evidence_id": "EV-PDB-7R95-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7R95", "doi": "10.1126/sciadv.abk2226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Membrane bound structure of HR1 domain of SARS-CoV-2 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R8O", "evidence_id": "EV-PDB-7R8O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7R8O", "doi": "10.1016/j.immuni.2021.07.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R8O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C548"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R8N", "evidence_id": "EV-PDB-7R8N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "7R8N", "doi": "10.1016/j.immuni.2021.07.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R8N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R8M", "evidence_id": "EV-PDB-7R8M-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7R8M", "doi": "10.1016/j.immuni.2021.07.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R8M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C032"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SWO", "evidence_id": "EV-PDB-7SWO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7SWO", "doi": "10.1126/sciimmunol.abo3425", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SWO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "C98C7 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY6", "evidence_id": "EV-PDB-7SY6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "7SY6", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T01", "evidence_id": "EV-PDB-7T01-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "7T01", "doi": "10.1016/j.celrep.2021.109784", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T01"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S-RBD + Fab 54042-4"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY7", "evidence_id": "EV-PDB-7SY7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "7SY7", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY5", "evidence_id": "EV-PDB-7SY5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "7SY5", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY4", "evidence_id": "EV-PDB-7SY4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "7SY4", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY3", "evidence_id": "EV-PDB-7SY3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "7SY3", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY2", "evidence_id": "EV-PDB-7SY2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "7SY2", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY1", "evidence_id": "EV-PDB-7SY1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "7SY1", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXZ", "evidence_id": "EV-PDB-7SXZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "7SXZ", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,L452R mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXY", "evidence_id": "EV-PDB-7SXY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "7SXY", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXX", "evidence_id": "EV-PDB-7SXX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "7SXX", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXW", "evidence_id": "EV-PDB-7SXW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7SXW", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXV", "evidence_id": "EV-PDB-7SXV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "7SXV", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXT", "evidence_id": "EV-PDB-7SXT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.31}, "provenance": {"deposit_id": "7SXT", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y mutant spike protein ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXS", "evidence_id": "EV-PDB-7SXS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.64}, "provenance": {"deposit_id": "7SXS", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,L452R mutant spike protein ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXR", "evidence_id": "EV-PDB-7SXR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7SXR", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SWX", "evidence_id": "EV-PDB-7SWX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "7SWX", "doi": "10.1016/j.xcrm.2023.101305", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SWX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-57 (three down conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SWW", "evidence_id": "EV-PDB-7SWW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "7SWW", "doi": "10.1016/j.xcrm.2023.101305", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SWW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SWP", "evidence_id": "EV-PDB-7SWP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7SWP", "doi": "10.1126/sciimmunol.abo3425", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SWP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "G32Q4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SPP", "evidence_id": "EV-PDB-7SPP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "7SPP", "doi": "10.1038/s41467-021-27611-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SPP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 receptor binding domain in complex with VNAR 2C02"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SPO", "evidence_id": "EV-PDB-7SPO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.92}, "provenance": {"deposit_id": "7SPO", "doi": "10.1038/s41467-021-27611-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SPO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 receptor binding domain in complex with VNAR 3B4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SOF", "evidence_id": "EV-PDB-7SOF-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7SOF", "doi": "10.1126/science.abl8506", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SOF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S NTD B.1.617.1 kappa variant S2X303 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SOE", "evidence_id": "EV-PDB-7SOE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7SOE", "doi": "10.1126/science.abl8506", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SOE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S B.1.617.1 kappa variant + S2X303 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SOD", "evidence_id": "EV-PDB-7SOD-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7SOD", "doi": "10.1126/science.abl8506", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SOD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S NTD B.1.617.1 kappa variant S2L20 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SOC", "evidence_id": "EV-PDB-7SOC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7SOC", "doi": "10.1126/science.abl8506", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SOC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S RBD B.1.617.1 kappa variant S309 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,D,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SOB", "evidence_id": "EV-PDB-7SOB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7SOB", "doi": "10.1126/science.abl8506", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SOB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S B.1.617.1 kappa variant + S309 + S2L20 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SOA", "evidence_id": "EV-PDB-7SOA-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7SOA", "doi": "10.1126/science.abl8506", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SOA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S NTD B.1.617.2 delta variant + S2L20 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,F,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SO9", "evidence_id": "EV-PDB-7SO9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7SO9", "doi": "10.1126/science.abl8506", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S B.1.617.2 delta variant + S2M11 + S2L20 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SN2", "evidence_id": "EV-PDB-7SN2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7SN2", "doi": "10.1126/science.abl6251", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SARS-CoV-2 neutralizing antibody C1C-A3 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Surface glycoprotein (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SN0", "evidence_id": "EV-PDB-7SN0-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "7SN0", "doi": "10.1126/science.abl6251", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SN0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of spike protein receptor binding domain of escape mutant SARS-CoV-2 from immunocompromised patient (d146*) in complex with human receptor ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN (chains C,F,I,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SL5", "evidence_id": "EV-PDB-7SL5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7SL5", "doi": "10.1126/science.abq2679", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SL5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of VP12E7 Fab in complex with SARS-CoV-2 S fusion peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SKZ", "evidence_id": "EV-PDB-7SKZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "7SKZ", "doi": "10.1126/science.abq2679", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SKZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of VN01H1 Fab in complex with SARS-CoV-2 S fusion peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.26, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "stem helix peptide of Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SJS", "evidence_id": "EV-PDB-7SJS-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.612}, "provenance": {"deposit_id": "7SJS", "doi": "10.1126/scitranslmed.abi9215", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SJS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SJ0", "evidence_id": "EV-PDB-7SJ0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "7SJ0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SJ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Antibody A7V3 bound to N-terminal domain of the spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CD", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' peptide VLNDILSRL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SIS", "evidence_id": "EV-PDB-7SIS-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "7SIS", "doi": "10.1016/j.crstbi.2024.100148", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SIS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Spike-derived peptide S976-984 (VLNDILSRL) presented by HLA-A*02:01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SI2", "evidence_id": "EV-PDB-7SI2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7SI2", "doi": "10.1126/scitranslmed.abn6859", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SI2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of neutralizing antibody 10-28 in complex with SARS-CoV-2 spike receptor binding domain (RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SD5", "evidence_id": "EV-PDB-7SD5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "7SD5", "doi": "10.1126/scitranslmed.abn6859", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SD5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SC1", "evidence_id": "EV-PDB-7SC1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7SC1", "doi": "10.1016/j.chom.2021.12.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SC1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, R40-1G8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SBT", "evidence_id": "EV-PDB-7SBT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7SBT", "doi": "10.1126/science.abl9463", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SBT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "One RBD-up 2 of pre-fusion SARS-CoV-2 Gamma variant spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SBS", "evidence_id": "EV-PDB-7SBS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7SBS", "doi": "10.1126/science.abl9463", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SBS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "One RBD-up 1 of pre-fusion SARS-CoV-2 Gamma variant spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SBR", "evidence_id": "EV-PDB-7SBR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7SBR", "doi": "10.1126/science.abl9463", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SBR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "One RBD-up 2 of pre-fusion SARS-CoV-2 Kappa variant spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SBQ", "evidence_id": "EV-PDB-7SBQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7SBQ", "doi": "10.1126/science.abl9463", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SBQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "One RBD-up 1 of pre-fusion SARS-CoV-2 Kappa variant spike protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T3M", "evidence_id": "EV-PDB-7T3M-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7T3M", "doi": "10.1038/s41467-022-33030-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T3M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S (Spike Glycoprotein) D614G with Three (3) RBDs Up, Bound to Antibody 2-7 scFv, composite map"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T5O", "evidence_id": "EV-PDB-7T5O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "7T5O", "doi": "10.1038/s41467-023-36295-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T5O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VFLIP Spike Trimer with GAR03"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T67", "evidence_id": "EV-PDB-7T67-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7T67", "doi": "10.1038/s41467-022-33030-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T67"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T72", "evidence_id": "EV-PDB-7T72-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.177}, "provenance": {"deposit_id": "7T72", "doi": "10.1038/s41467-023-36295-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T72"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Epitope-based selection of SARS-CoV-2 neutralizing antibodies from convalescent patients"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T7B", "evidence_id": "EV-PDB-7T7B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "7T7B", "doi": "10.1038/s42003-022-03700-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T7B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T9J", "evidence_id": "EV-PDB-7T9J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "7T9J", "doi": "10.1126/science.abn7760", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 Omicron spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T9K", "evidence_id": "EV-PDB-7T9K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "7T9K", "doi": "10.1126/science.abn7760", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T9K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T9L", "evidence_id": "EV-PDB-7T9L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "7T9L", "doi": "10.1126/science.abn7760", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T9L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TAS", "evidence_id": "EV-PDB-7TAS-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7TAS", "doi": "10.1126/science.abm8143", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TAS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (local refinement of the RBD and S2K146)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TAT", "evidence_id": "EV-PDB-7TAT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7TAT", "doi": "10.1126/science.abm8143", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TAT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Surface glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TB4", "evidence_id": "EV-PDB-7TB4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7TB4", "doi": "10.1101/2021.02.25.432969", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TB4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the spike of SARS-CoV-2 Omicron variant of concern"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TB8", "evidence_id": "EV-PDB-7TB8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "7TB8", "doi": "10.1126/science.abn8897", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TB8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TBF", "evidence_id": "EV-PDB-7TBF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7TBF", "doi": "10.1126/science.abn8897", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TBF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Locally refined region of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TC9", "evidence_id": "EV-PDB-7TC9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.08}, "provenance": {"deposit_id": "7TC9", "doi": "10.1126/science.abn8897", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TC9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Locally refined region of SARS-CoV-2 spike in complex with antibody A19-46.1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TF1", "evidence_id": "EV-PDB-7TF1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.57}, "provenance": {"deposit_id": "7TF1", "doi": "10.1038/s41467-022-28324-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TF1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) Q484I spike protein (focused refinement of RBD)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TGW", "evidence_id": "EV-PDB-7TGW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7TGW", "doi": "10.1038/s41467-022-28882-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron spike at 3.0 A (open form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MAN", "NAG", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TGX", "evidence_id": "EV-PDB-7TGX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7TGX", "doi": "10.1038/s41467-022-28882-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TGX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prototypic SARS-CoV-2 G614 spike (open form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TGY", "evidence_id": "EV-PDB-7TGY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7TGY", "doi": "10.1038/s41467-022-28882-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TGY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prototypic SARS-CoV-2 G614 spike (closed form)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7THE", "evidence_id": "EV-PDB-7THE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.87}, "provenance": {"deposit_id": "7THE", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7THE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of RBD directed antibody DH1042 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interface"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7THK", "evidence_id": "EV-PDB-7THK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "7THK", "doi": "10.1016/j.celrep.2022.110428", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7THK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of prefusion SARS-CoV-2 spike omicron B.1.1.529 variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,S,V)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7THT", "evidence_id": "EV-PDB-7THT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "7THT", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7THT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TIK", "evidence_id": "EV-PDB-7TIK-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7TIK", "doi": "10.1073/pnas.2300360120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TIK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Omicron spike post-fusion bundle"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ferritin, Dps family protein and Spike protein S2' chimera (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TIK", "evidence_id": "EV-PDB-7TIK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7TIK", "doi": "10.1073/pnas.2300360120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TIK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Omicron spike post-fusion bundle"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TL1", "evidence_id": "EV-PDB-7TL1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7TL1", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TL1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TLD", "evidence_id": "EV-PDB-7TLD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "7TLD", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TLD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Down-state locked, S2 stabilized rS2d-HexaPro SARS-CoV-2 spike ectodomain in the RBD-down conformation, State 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "NA", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 peptide (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TLT", "evidence_id": "EV-PDB-7TLT-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7TLT", "doi": "10.1038/s41467-022-34180-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TLT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Spike-derived peptide S489-497 (YFPLQSYGF) presented by HLA-A*29:02"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TLY", "evidence_id": "EV-PDB-7TLY-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7TLY", "doi": "10.1126/science.abn8652", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TLY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S B.1.1.529 Omicron variant (RBD + S309 Local Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TLZ", "evidence_id": "EV-PDB-7TLZ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7TLZ", "doi": "10.1126/science.abn8652", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S NTD B.1.1.529 Omicron variant + S309 Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TM0", "evidence_id": "EV-PDB-7TM0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7TM0", "doi": "10.1126/science.abn8652", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S B.1.1.529 Omicron variant + S309 + S2L20 Global Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains I,S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TN0", "evidence_id": "EV-PDB-7TN0-6", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7TN0", "doi": "10.1126/science.abn8652", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TN0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TNW", "evidence_id": "EV-PDB-7TNW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7TNW", "doi": "10.1016/j.celrep.2022.110729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TNW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural and functional impact by SARS-CoV-2 Omicron spike mutations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TLC", "evidence_id": "EV-PDB-7TLC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "7TLC", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TLC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Down-state locked, S2 stabilized rS2d-HexaPro SARS-CoV-2 spike ectodomain in the RBD-down conformation, State 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TLB", "evidence_id": "EV-PDB-7TLB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "7TLB", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TLB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Down-state locked rS2d SARS-CoV-2 spike ectodomain in the RBD-down conformation, State 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TLA", "evidence_id": "EV-PDB-7TLA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "7TLA", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TLA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Down-state locked rS2d SARS-CoV-2 spike ectodomain in the RBD-down conformation, State 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TL9", "evidence_id": "EV-PDB-7TL9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7TL9", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TL9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TGE", "evidence_id": "EV-PDB-7TGE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.68}, "provenance": {"deposit_id": "7TGE", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TGE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 1-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TF8", "evidence_id": "EV-PDB-7TF8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "7TF8", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TF8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TF3", "evidence_id": "EV-PDB-7TF3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "7TF3", "doi": "10.1038/s41467-022-28324-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TF3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) Q484A spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TF0", "evidence_id": "EV-PDB-7TF0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "7TF0", "doi": "10.1038/s41467-022-28324-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TF0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TEY", "evidence_id": "EV-PDB-7TEY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "7TEY", "doi": "10.1038/s41467-022-28324-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TEY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Delta (B.1.617.2) spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TEW", "evidence_id": "EV-PDB-7TEW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "7TEW", "doi": "10.1038/s41467-022-28324-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TEW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Delta (B.1.617.2) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TEI", "evidence_id": "EV-PDB-7TEI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7TEI", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TEI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Pegylated spike S2 peptide (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TCQ", "evidence_id": "EV-PDB-7TCQ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "7TCQ", "doi": "10.1016/j.str.2022.06.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TCQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TO4", "evidence_id": "EV-PDB-7TO4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7TO4", "doi": "10.1016/j.celrep.2022.110729", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TO4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural and functional impact by SARS-CoV-2 Omicron spike mutations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TOU", "evidence_id": "EV-PDB-7TOU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7TOU", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; consensus state D1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TOV", "evidence_id": "EV-PDB-7TOV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "7TOV", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; consensus state D2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TOW", "evidence_id": "EV-PDB-7TOW-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "7TOW", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Antibody DH1058 Fab fragment bound to SARS-CoV-2 fusion peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TOX", "evidence_id": "EV-PDB-7TOX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.62}, "provenance": {"deposit_id": "7TOX", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TOX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D5 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TOY", "evidence_id": "EV-PDB-7TOY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "7TOY", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TOY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D6 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TOZ", "evidence_id": "EV-PDB-7TOZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.07}, "provenance": {"deposit_id": "7TOZ", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TOZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D7 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP0", "evidence_id": "EV-PDB-7TP0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.57}, "provenance": {"deposit_id": "7TP0", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D8 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP1", "evidence_id": "EV-PDB-7TP1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.81}, "provenance": {"deposit_id": "7TP1", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D9 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP2", "evidence_id": "EV-PDB-7TP2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "7TP2", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 3-RBD-down conformation; Subclassification D10 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CAC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP3", "evidence_id": "EV-PDB-7TP3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33}, "provenance": {"deposit_id": "7TP3", "doi": "10.1126/scitranslmed.abl9605", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP4", "evidence_id": "EV-PDB-7TP4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "7TP4", "doi": "10.1126/scitranslmed.abl9605", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP7", "evidence_id": "EV-PDB-7TP7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "7TP7", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D11 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP8", "evidence_id": "EV-PDB-7TP8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7TP8", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D12 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TP9", "evidence_id": "EV-PDB-7TP9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "7TP9", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TP9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D13 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPA", "evidence_id": "EV-PDB-7TPA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7TPA", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D14 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPC", "evidence_id": "EV-PDB-7TPC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.91}, "provenance": {"deposit_id": "7TPC", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D15 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPE", "evidence_id": "EV-PDB-7TPE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7TPE", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D16 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPF", "evidence_id": "EV-PDB-7TPF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7TPF", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D17 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPH", "evidence_id": "EV-PDB-7TPH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.58}, "provenance": {"deposit_id": "7TPH", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 2-RBD-up conformation - D3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPI", "evidence_id": "EV-PDB-7TPI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7TPI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 E406W mutant Spike ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPK", "evidence_id": "EV-PDB-7TPK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7TPK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 E406W mutant RBD - Local Refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPL", "evidence_id": "EV-PDB-7TPL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.87}, "provenance": {"deposit_id": "7TPL", "doi": "10.1016/j.molcel.2022.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the M1 conformation, D4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TPR", "evidence_id": "EV-PDB-7TPR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "7TPR", "doi": "10.1101/2021.10.27.465996", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TZ0", "evidence_id": "EV-PDB-7TZ0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.17}, "provenance": {"deposit_id": "7TZ0", "doi": "10.1038/s41589-022-01193-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TZ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin (Local refinement of FSR22 and RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Surface glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U0D", "evidence_id": "EV-PDB-7U0D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8}, "provenance": {"deposit_id": "7U0D", "doi": "10.1126/science.abn8897", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U0D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U0P", "evidence_id": "EV-PDB-7U0P-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76}, "provenance": {"deposit_id": "7U0P", "doi": "10.1126/sciadv.add2032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U0P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21F2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U0Q", "evidence_id": "EV-PDB-7U0Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.86}, "provenance": {"deposit_id": "7U0Q", "doi": "10.1016/j.str.2023.04.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U0Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-02"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U0X", "evidence_id": "EV-PDB-7U0X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.82}, "provenance": {"deposit_id": "7U0X", "doi": "10.1016/j.str.2023.04.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-13"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CD", "CL", "NA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' peptide (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U1R", "evidence_id": "EV-PDB-7U1R-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "7U1R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U1R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Spike-derived peptide S1185-1193 K1191N mutant (RLNEVANNL) presented by HLA-A*02:01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.16, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U2D", "evidence_id": "EV-PDB-7U2D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "7U2D", "doi": "10.1073/pnas.2205784119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U2D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADG20"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U2E", "evidence_id": "EV-PDB-7U2E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7U2E", "doi": "10.1073/pnas.2205784119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U2E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADI-55688"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U8E", "evidence_id": "EV-PDB-7U8E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.29}, "provenance": {"deposit_id": "7U8E", "doi": "10.1016/j.str.2023.11.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U8E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of antibody Ab246 in complex with SARS-CoV-2 receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U9O", "evidence_id": "EV-PDB-7U9O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7U9O", "doi": "10.1016/j.celrep.2022.111528", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U9O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer RBD in complex with Fab NE12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U9P", "evidence_id": "EV-PDB-7U9P-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7U9P", "doi": "10.1016/j.celrep.2022.111528", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer RBD in complex with Fab NA8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UAP", "evidence_id": "EV-PDB-7UAP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7UAP", "doi": "10.1016/j.immuni.2022.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UAP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1520"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UAQ", "evidence_id": "EV-PDB-7UAQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7UAQ", "doi": "10.1016/j.immuni.2022.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UAQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 NTD in complex with C1520, local refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UAR", "evidence_id": "EV-PDB-7UAR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7UAR", "doi": "10.1016/j.immuni.2022.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UAR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1717"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UB0", "evidence_id": "EV-PDB-7UB0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31}, "provenance": {"deposit_id": "7UB0", "doi": "10.1016/j.celrep.2022.111009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-BA.2 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron-BA.2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UB5", "evidence_id": "EV-PDB-7UB5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "7UB5", "doi": "10.1016/j.celrep.2022.111009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-BA.2 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron-BA.2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UB6", "evidence_id": "EV-PDB-7UB6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "7UB6", "doi": "10.1016/j.celrep.2022.111009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UB6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-BA.2 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron-BA.2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UFK", "evidence_id": "EV-PDB-7UFK-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.38}, "provenance": {"deposit_id": "7UFK", "doi": "10.1073/pnas.2206509119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UFK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric omicron RBD (strain BA.2) complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UFL", "evidence_id": "EV-PDB-7UFL-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "7UFL", "doi": "10.1073/pnas.2206509119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UFL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric omicron RBD (strain BA.2) complexed with chimeric mouse ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UHB", "evidence_id": "EV-PDB-7UHB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7UHB", "doi": "10.1126/scitranslmed.abn1252", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UHB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UHC", "evidence_id": "EV-PDB-7UHC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7UHC", "doi": "10.1126/scitranslmed.abn1252", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UHC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with AHB2-2GS-SB175"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UKL", "evidence_id": "EV-PDB-7UKL-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09}, "provenance": {"deposit_id": "7UKL", "doi": "10.1016/j.immuni.2023.09.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UKL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Antibody 12-16 in complex with prefusion SARS-CoV-2 Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UKM", "evidence_id": "EV-PDB-7UKM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "7UKM", "doi": "10.1016/j.immuni.2023.09.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UKM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Antibody 12-19 in complex with prefusion SARS-CoV-2 Spike glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UL0", "evidence_id": "EV-PDB-7UL0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.49}, "provenance": {"deposit_id": "7UL0", "doi": "10.1016/j.isci.2022.105783", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UL0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with the ridge-binding nAb EH8 isolated from a nonvaccinated pediatric patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UL1", "evidence_id": "EV-PDB-7UL1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "7UL1", "doi": "10.1016/j.isci.2022.105783", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UL1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing IGHV3-53-encoded antibody EH3 isolated from a nonvaccinated pediatric patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TYZ", "evidence_id": "EV-PDB-7TYZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "7TYZ", "doi": "10.1038/s41589-022-01193-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TYZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD", "NA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UM2", "evidence_id": "EV-PDB-7UM2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.63}, "provenance": {"deposit_id": "7UM2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UM2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UOW", "evidence_id": "EV-PDB-7UOW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7UOW", "doi": "10.1016/j.str.2023.04.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 034_32"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UPL", "evidence_id": "EV-PDB-7UPL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7UPL", "doi": "10.1126/sciadv.add2032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UPL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 Omicron varient S protein structure in complex with neutralizing monoclonal antibody 002-S21F2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UPW", "evidence_id": "EV-PDB-7UPW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7UPW", "doi": "10.1126/sciimmunol.add5446", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UPW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UPX", "evidence_id": "EV-PDB-7UPX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7UPX", "doi": "10.1126/sciimmunol.add5446", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UPX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UPY", "evidence_id": "EV-PDB-7UPY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7UPY", "doi": "10.1126/sciimmunol.add5446", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UPY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UR1", "evidence_id": "EV-PDB-7UR1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.17}, "provenance": {"deposit_id": "7UR1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UR1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) presented by HLA-A*02:01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7URQ", "evidence_id": "EV-PDB-7URQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "7URQ", "doi": "10.3389/fimmu.2023.1178355", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7URQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SARS-CoV-2 S delta variant receptor-binding domain (RBD) in complex CoV11 Fab crystal form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPD", "NAG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7URS", "evidence_id": "EV-PDB-7URS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7URS", "doi": "10.3389/fimmu.2023.1178355", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7URS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SARS-CoV-2 S delta variant receptor-binding domain (RBD) in complex CoV11 Fab crystal form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZ4", "evidence_id": "EV-PDB-7UZ4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7UZ4", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZ5", "evidence_id": "EV-PDB-7UZ5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7UZ5", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZ6", "evidence_id": "EV-PDB-7UZ6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7UZ6", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-28"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZ7", "evidence_id": "EV-PDB-7UZ7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7UZ7", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZ8", "evidence_id": "EV-PDB-7UZ8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7UZ8", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Omicron BA.1 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZ9", "evidence_id": "EV-PDB-7UZ9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7UZ9", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZA", "evidence_id": "EV-PDB-7UZA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7UZA", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, HSW-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZB", "evidence_id": "EV-PDB-7UZB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7UZB", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S S1 doamin in complex with the mouse antibody Fab fragment, HSW-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZC", "evidence_id": "EV-PDB-7UZC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "7UZC", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, M8a-34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZD", "evidence_id": "EV-PDB-7UZD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7UZD", "doi": "10.1016/j.immuni.2022.10.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, HSW-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V20", "evidence_id": "EV-PDB-7V20-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "7V20", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V20"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of del68-76/del679-688 prefusion-stabilized spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V22", "evidence_id": "EV-PDB-7V22-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "7V22", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V22"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local CryoEM structure del68-76/del679-688 prefusion-stabilized spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V23", "evidence_id": "EV-PDB-7V23-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "7V23", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V23"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V24", "evidence_id": "EV-PDB-7V24-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7V24", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V24"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V26", "evidence_id": "EV-PDB-7V26-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "7V26", "doi": "10.1007/s13238-021-00871-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V26"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XG005-bound SARS-CoV-2 S"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V27", "evidence_id": "EV-PDB-7V27-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.18}, "provenance": {"deposit_id": "7V27", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V27"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RBD/XG005 local refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V2A", "evidence_id": "EV-PDB-7V2A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7V2A", "doi": "10.1007/s13238-021-00871-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V2A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike trimer in complex with XG014 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V76", "evidence_id": "EV-PDB-7V76-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7V76", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V76"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, one RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V77", "evidence_id": "EV-PDB-7V77-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7V77", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V77"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), uncleavable form, two RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V78", "evidence_id": "EV-PDB-7V78-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7V78", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V78"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), one RBD-up conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7A", "evidence_id": "EV-PDB-7V7A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7V7A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), two RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7D", "evidence_id": "EV-PDB-7V7D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7V7D", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), all RBD-down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7E", "evidence_id": "EV-PDB-7V7E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7V7E", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), one RBD-up conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7F", "evidence_id": "EV-PDB-7V7F-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7V7F", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), one RBD-up conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7G", "evidence_id": "EV-PDB-7V7G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7V7G", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), two RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7H", "evidence_id": "EV-PDB-7V7H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7V7H", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7I", "evidence_id": "EV-PDB-7V7I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7V7I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7J", "evidence_id": "EV-PDB-7V7J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7V7J", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1), dimer of S trimer conformation 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7N", "evidence_id": "EV-PDB-7V7N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7V7N", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), all RBD-down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7O", "evidence_id": "EV-PDB-7V7O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7V7O", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7P", "evidence_id": "EV-PDB-7V7P-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7V7P", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7Q", "evidence_id": "EV-PDB-7V7Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7V7Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7R", "evidence_id": "EV-PDB-7V7R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7V7R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7S", "evidence_id": "EV-PDB-7V7S-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7V7S", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), one RBD-up conformation 5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7T", "evidence_id": "EV-PDB-7V7T-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7V7T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7U", "evidence_id": "EV-PDB-7V7U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7V7U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7V", "evidence_id": "EV-PDB-7V7V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7V7V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2), two RBD-up conformation 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7Z", "evidence_id": "EV-PDB-7V7Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7V7Z", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V80", "evidence_id": "EV-PDB-7V80-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7V80", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V80"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 S-Beta variant (B.1.351) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V81", "evidence_id": "EV-PDB-7V81-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7V81", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V81"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V79", "evidence_id": "EV-PDB-7V79-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7V79", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V79"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1), one RBD-up conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V82", "evidence_id": "EV-PDB-7V82-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7V82", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V82"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V83", "evidence_id": "EV-PDB-7V83-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7V83", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V83"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V84", "evidence_id": "EV-PDB-7V84-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7V84", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V84"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 S-Gamma variant (P.1) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V85", "evidence_id": "EV-PDB-7V85-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7V85", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V85"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V86", "evidence_id": "EV-PDB-7V86-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7V86", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V86"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Kappa variant (B.1.617.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V87", "evidence_id": "EV-PDB-7V87-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7V87", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V87"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 S-Kappa variant (B.1.617.1) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V89", "evidence_id": "EV-PDB-7V89-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7V89", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V89"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V8A", "evidence_id": "EV-PDB-7V8A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7V8A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V8A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Delta variant (B.1.617.2) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V8B", "evidence_id": "EV-PDB-7V8B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7V8B", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V8B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 S-Delta variant (B.1.617.2) RBD and Angiotensin-converting enzyme 2 (ACE2) ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V8C", "evidence_id": "EV-PDB-7V8C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7V8C", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V8C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351), Cleavable form, one RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VHH", "evidence_id": "EV-PDB-7VHH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7VHH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VHH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta variant of SARS-CoV-2 Spike protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VHM", "evidence_id": "EV-PDB-7VHM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7VHM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VHM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Double deletion S-2P trimer(3 down)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VMU", "evidence_id": "EV-PDB-7VMU-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "7VMU", "doi": "10.1186/s13578-022-00794-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VMU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SARS-CoV Spike Receptor-Binding Domain Complexed with Neutralizing Antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VNB", "evidence_id": "EV-PDB-7VNB-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.27}, "provenance": {"deposit_id": "7VNB", "doi": "10.1038/s41392-021-00810-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VNB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD in complex with a human single domain antibody n3113"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VNC", "evidence_id": "EV-PDB-7VNC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7VNC", "doi": "10.1038/s41392-021-00810-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VNC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein in complex with a human single domain antibody n3113 (UDD-state, state 1)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VQ0", "evidence_id": "EV-PDB-7VQ0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "7VQ0", "doi": "10.1038/s42003-022-03630-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VQ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike protein (2-up RBD) bound to neutralizing nanobodies P86"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VX5", "evidence_id": "EV-PDB-7VX5-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7VX5", "doi": "10.1038/s41467-021-27350-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ACE2-RBD in SARS-CoV-2 Kappa variant S-ACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VX9", "evidence_id": "EV-PDB-7VX9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7VX9", "doi": "10.1038/s41467-021-27350-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Kappa variant spike protein in complex wth ACE2, state C1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VXE", "evidence_id": "EV-PDB-7VXE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7VXE", "doi": "10.1038/s41467-021-27350-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VXE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Kappa variant spike protein in open state"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7W9E", "evidence_id": "EV-PDB-7W9E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7W9E", "doi": "10.1038/s41467-022-28528-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7W9E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta S-8D3"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WBL", "evidence_id": "EV-PDB-7WBL-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WBL", "doi": "10.1016/j.cell.2022.01.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WBL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human ACE2 complexed with SARS-CoV-2 Omicron RBD"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,H,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WCD", "evidence_id": "EV-PDB-7WCD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7WCD", "doi": "10.1038/s42003-022-03739-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WCD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of SARS-CoV-2 spike in complex with TAU-2212 mAbs in conformation 4"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Surface glycoprotein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WCK", "evidence_id": "EV-PDB-7WCK-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "7WCK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WCK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWA9 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Surface glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WCP", "evidence_id": "EV-PDB-7WCP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "7WCP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WCP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWC11 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WCR", "evidence_id": "EV-PDB-7WCR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WCR", "doi": "10.1080/22221751.2021.2024455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WCR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RBD-1 of SARS-CoV-2 Beta spike in complex with S5D2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Surface glycoprotein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WCU", "evidence_id": "EV-PDB-7WCU-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09}, "provenance": {"deposit_id": "7WCU", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WCU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWC11 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WCZ", "evidence_id": "EV-PDB-7WCZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WCZ", "doi": "10.1080/22221751.2021.2024455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WCZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Beta spike in complex with one S5D2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WD0", "evidence_id": "EV-PDB-7WD0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7WD0", "doi": "10.1080/22221751.2021.2024455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WD0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Beta spike in complex with two S5D2 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WD1", "evidence_id": "EV-PDB-7WD1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7WD1", "doi": "10.1016/j.xcrm.2023.100918", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WD1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of R14 bound to SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WD2", "evidence_id": "EV-PDB-7WD2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "7WD2", "doi": "10.1016/j.xcrm.2023.100918", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WD2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of S43 bound to SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WD7", "evidence_id": "EV-PDB-7WD7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WD7", "doi": "10.1080/22221751.2021.2024455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WD7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Beta spike in complex with three S5D2 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WD8", "evidence_id": "EV-PDB-7WD8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7WD8", "doi": "10.1080/22221751.2021.2024455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WD8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Beta spike SD1 in complex with S3H3 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WD9", "evidence_id": "EV-PDB-7WD9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7WD9", "doi": "10.1080/22221751.2021.2024455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WD9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Beta spike in complex with three S3H3 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WDF", "evidence_id": "EV-PDB-7WDF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7WDF", "doi": "10.1080/22221751.2021.2024455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WDF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Beta spike in complex with two S3H3 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains D,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WE7", "evidence_id": "EV-PDB-7WE7-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7WE7", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WE8", "evidence_id": "EV-PDB-7WE8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WE8", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WE9", "evidence_id": "EV-PDB-7WE9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7WE9", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WE9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv289"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WEA", "evidence_id": "EV-PDB-7WEA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7WEA", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike protein in complex with two XGv347 binding to one close state RBD and one open state RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WEC", "evidence_id": "EV-PDB-7WEC-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7WEC", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WED", "evidence_id": "EV-PDB-7WED-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WED", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WED"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv347"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WEE", "evidence_id": "EV-PDB-7WEE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7WEE", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WEE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv265"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WEF", "evidence_id": "EV-PDB-7WEF-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7WEF", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WEF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv289"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WEV", "evidence_id": "EV-PDB-7WEV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7WEV", "doi": "10.1038/s42003-021-02399-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WEV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-COV-2 BETA VARIANT SPIKE PROTEIN IN TRANSITION STATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WG6", "evidence_id": "EV-PDB-7WG6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WG6", "doi": "10.1016/j.cell.2022.01.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WG6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Neutral Omicron Spike Trimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WG7", "evidence_id": "EV-PDB-7WG7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7WG7", "doi": "10.1016/j.cell.2022.01.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WG7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Acidic Omicron Spike Trimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WG8", "evidence_id": "EV-PDB-7WG8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7WG8", "doi": "10.1016/j.cell.2022.01.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WG8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta Spike Trimer(3 RBD Down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WG9", "evidence_id": "EV-PDB-7WG9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WG9", "doi": "10.1016/j.cell.2022.01.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WG9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta Spike Trimer(1 RBD Up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WGB", "evidence_id": "EV-PDB-7WGB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WGB", "doi": "10.1016/j.cell.2022.01.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WGB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Neutral Omicron Spike Trimer in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLR", "EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WGV", "evidence_id": "EV-PDB-7WGV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7WGV", "doi": "10.1038/s41421-022-00419-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WGV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike glycoprotein trimer in closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLR", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WGX", "evidence_id": "EV-PDB-7WGX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WGX", "doi": "10.1038/s41421-022-00419-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WGX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike glycoprotein trimer in closed state after treatment with Cathepsin L"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WGY", "evidence_id": "EV-PDB-7WGY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7WGY", "doi": "10.1038/s41421-022-00419-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WGY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike glycoprotein trimer in Intermediate state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WGZ", "evidence_id": "EV-PDB-7WGZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "7WGZ", "doi": "10.1038/s41421-022-00419-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WGZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike glycoprotein trimer in open state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WHB", "evidence_id": "EV-PDB-7WHB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67}, "provenance": {"deposit_id": "7WHB", "doi": "10.1080/22221751.2023.2245921", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WHB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (3U)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WHD", "evidence_id": "EV-PDB-7WHD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "7WHD", "doi": "10.1080/22221751.2023.2245921", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WHD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (2u1d)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WHH", "evidence_id": "EV-PDB-7WHH-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7WHH", "doi": "10.1038/s41422-022-00644-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WHH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 omicron RBD and human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WHI", "evidence_id": "EV-PDB-7WHI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.93}, "provenance": {"deposit_id": "7WHI", "doi": "10.1016/j.cell.2022.03.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WHI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WHJ", "evidence_id": "EV-PDB-7WHJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "7WHJ", "doi": "10.1016/j.cell.2022.03.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WHJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WH8", "evidence_id": "EV-PDB-7WH8-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "7WH8", "doi": "10.1080/22221751.2023.2245921", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WH8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (focused refinement on Fab-RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WGC", "evidence_id": "EV-PDB-7WGC-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7WGC", "doi": "10.1016/j.cell.2022.01.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WGC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Neutral Omicron Spike Trimer in complex with ACE2."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WEB", "evidence_id": "EV-PDB-7WEB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7WEB", "doi": "10.1038/s41586-022-04466-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike protein with two XGv347 binding to two open state RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPF", "evidence_id": "EV-PDB-7WPF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "7WPF", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron Variant S Trimer complexed with three JMB2002 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPH", "evidence_id": "EV-PDB-7WPH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "7WPH", "doi": "10.1038/s41467-022-33284-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV2 RBD bound to Fab06"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPE", "evidence_id": "EV-PDB-7WPE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "7WPE", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron Variant S Trimer complexed with two JMB2002 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPD", "evidence_id": "EV-PDB-7WPD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "7WPD", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron Variant S Trimer complexed with one JMB2002 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPC", "evidence_id": "EV-PDB-7WPC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "7WPC", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The second RBD of SARS-CoV-2 Omicron Variant in complexed with RBD-ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPB", "evidence_id": "EV-PDB-7WPB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "7WPB", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron Variant RBD complexed with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPA", "evidence_id": "EV-PDB-7WPA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "7WPA", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron Variant SPIKE trimer complexed with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WP9", "evidence_id": "EV-PDB-7WP9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "7WP9", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WP9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron Variant SPIKE trimer, all RBDs down"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WP8", "evidence_id": "EV-PDB-7WP8-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88}, "provenance": {"deposit_id": "7WP8", "doi": "10.1016/j.chom.2022.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WP6", "evidence_id": "EV-PDB-7WP6-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.81}, "provenance": {"deposit_id": "7WP6", "doi": "10.1016/j.chom.2022.10.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WP6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spikeprotein S1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WP5", "evidence_id": "EV-PDB-7WP5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7WP5", "doi": "10.1038/s41422-022-00638-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WP5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WP2", "evidence_id": "EV-PDB-7WP2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "7WP2", "doi": "10.1038/s41422-022-00638-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WP2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 C.1.2 S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WP1", "evidence_id": "EV-PDB-7WP1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.77}, "provenance": {"deposit_id": "7WP1", "doi": "10.1038/s41422-022-00638-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WP1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Mu S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WP0", "evidence_id": "EV-PDB-7WP0-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.71}, "provenance": {"deposit_id": "7WP0", "doi": "10.1038/s41422-022-00638-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WP0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Delta S6P trimer in complex with neutralizing antibody VacW-209 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WOW", "evidence_id": "EV-PDB-7WOW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.11}, "provenance": {"deposit_id": "7WOW", "doi": "10.1038/s41421-022-00463-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The state 6 of Omicron Spike with bispecific antibody FD01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WOV", "evidence_id": "EV-PDB-7WOV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.87}, "provenance": {"deposit_id": "7WOV", "doi": "10.1038/s41421-022-00463-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The state 5 of Omicron Spike with bispecific antibody FD01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WOU", "evidence_id": "EV-PDB-7WOU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "7WOU", "doi": "10.1038/s41421-022-00463-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The state 4 of Omicron Spike with bispecific antibody FD01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WOS", "evidence_id": "EV-PDB-7WOS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.91}, "provenance": {"deposit_id": "7WOS", "doi": "10.1038/s41421-022-00463-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WOS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The state 3 of Omicron Spike with bispecific antibody FD01"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WO7", "evidence_id": "EV-PDB-7WO7-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7WO7", "doi": "10.1128/jvi.00480-22", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WO7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Locally refined region of SARS-CoV-2 Spike in complex with IgG 553-15"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WO5", "evidence_id": "EV-PDB-7WO5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "7WO5", "doi": "10.1128/jvi.00480-22", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WO5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with IgG 553-15 (S-553-15 trimer)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WO4", "evidence_id": "EV-PDB-7WO4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.47}, "provenance": {"deposit_id": "7WO4", "doi": "10.1128/jvi.00480-22", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WO4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with IgG 553-15 (S-553-15 dimer trimer )"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WNM", "evidence_id": "EV-PDB-7WNM-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7WNM", "doi": "10.1038/s41392-021-00821-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WNM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 Gamma variant receptor-binding domain complexed with high affinity human ACE2 mutant (T27F,R273Q)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WN2", "evidence_id": "EV-PDB-7WN2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "7WN2", "doi": "10.1038/s42003-023-04782-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain (RBD) in complex with NCV2SG53 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WM0", "evidence_id": "EV-PDB-7WM0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "7WM0", "doi": "10.1016/j.chom.2022.03.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Omicron RBD in complex with 35B5 Fab( local refinement of the RBD and 35B5 Fab)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WLZ", "evidence_id": "EV-PDB-7WLZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "7WLZ", "doi": "10.1016/j.chom.2022.03.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Omicron S in complex with 35B5 Fab(1 down-, 1 up- and 1 invisible RBDs)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WT7", "evidence_id": "EV-PDB-7WT7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WT7", "doi": "10.1038/s41421-022-00443-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WT7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WT8", "evidence_id": "EV-PDB-7WT8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7WT8", "doi": "10.1038/s41421-022-00443-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WT8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WT9", "evidence_id": "EV-PDB-7WT9-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7WT9", "doi": "10.1038/s41421-022-00443-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WT9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike RBD in complex with Fab 9A8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WTG", "evidence_id": "EV-PDB-7WTG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7WTG", "doi": "10.1038/s41422-022-00677-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WTG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv051"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WTH", "evidence_id": "EV-PDB-7WTH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "7WTH", "doi": "10.1038/s41422-022-00677-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WTH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv264"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WTI", "evidence_id": "EV-PDB-7WTI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7WTI", "doi": "10.1038/s41422-022-00677-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike in complex with Fab XGv264"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WTJ", "evidence_id": "EV-PDB-7WTJ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7WTJ", "doi": "10.1038/s41422-022-00677-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv286"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WTK", "evidence_id": "EV-PDB-7WTK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7WTK", "doi": "10.1038/s41422-022-00677-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WTK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron variant spike in complex with Fab XGv286"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WUE", "evidence_id": "EV-PDB-7WUE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7WUE", "doi": "10.1126/scitranslmed.abm0899", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WUE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Receptor Binding Domain in complex with the monoclonal antibody m31A7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WUH", "evidence_id": "EV-PDB-7WUH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.7}, "provenance": {"deposit_id": "7WUH", "doi": "10.1126/scitranslmed.abm0899", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WUH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike in complex with Fab of m31A7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WVL", "evidence_id": "EV-PDB-7WVL-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7WVL", "doi": "10.1371/journal.ppat.1010994", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WVL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of P4A2 Fab in complex with Spike-RBD from SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WVN", "evidence_id": "EV-PDB-7WVN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WVN", "doi": "10.1038/s41586-022-04581-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WVN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron S-open"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WVO", "evidence_id": "EV-PDB-7WVO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "7WVO", "doi": "10.1038/s41586-022-04581-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WVO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron S-open-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WVP", "evidence_id": "EV-PDB-7WVP-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7WVP", "doi": "10.1038/s41586-022-04581-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WVP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C2 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WVQ", "evidence_id": "EV-PDB-7WVQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.04}, "provenance": {"deposit_id": "7WVQ", "doi": "10.1038/s41586-022-04581-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C3 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WWI", "evidence_id": "EV-PDB-7WWI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WWI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WWI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab in the class 1 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WWJ", "evidence_id": "EV-PDB-7WWJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7WWJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab in the class 2 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WWK", "evidence_id": "EV-PDB-7WWK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WWK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WWK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of the SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7X2K", "evidence_id": "EV-PDB-7X2K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7X2K", "doi": "10.1038/s41467-022-35642-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7X2K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of nanobody Nb70 with antibody 1F11 fab and SARS-CoV-2 RBD"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7X6A", "evidence_id": "EV-PDB-7X6A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7X6A", "doi": "10.1038/s41586-022-04980-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7X6A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2 variant spike protein in complex with Fab BD55-5840"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,D,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7X7D", "evidence_id": "EV-PDB-7X7D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "7X7D", "doi": "10.3389/fimmu.2022.865401", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7X7D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Delta RBD and Nb22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,D,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7X7E", "evidence_id": "EV-PDB-7X7E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67}, "provenance": {"deposit_id": "7X7E", "doi": "10.3389/fimmu.2022.865401", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7X7E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 RBD and Nb22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7X7O", "evidence_id": "EV-PDB-7X7O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "7X7O", "doi": "10.1080/19420862.2022.2072455", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7X7O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XCK", "evidence_id": "EV-PDB-7XCK-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7XCK", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XCK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with S309 fab (local refinement)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XDA", "evidence_id": "EV-PDB-7XDA-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "7XDA", "doi": "10.1038/s41421-022-00509-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XDA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with BA7208 and BA7125 fab (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XDK", "evidence_id": "EV-PDB-7XDK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7XDK", "doi": "10.1038/s41421-022-00509-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XDK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7054 and BA7125 fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7X1M", "evidence_id": "EV-PDB-7X1M-7", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74}, "provenance": {"deposit_id": "7X1M", "doi": "10.1016/j.immuni.2022.06.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7X1M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The complex structure of Omicron BA.1 RBD with BD604, S309,and S304"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XIY", "evidence_id": "EV-PDB-7XIY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "7XIY", "doi": "10.1038/s41586-022-04980-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XIY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.3 variant spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XIZ", "evidence_id": "EV-PDB-7XIZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.74}, "provenance": {"deposit_id": "7XIZ", "doi": "10.1038/s41586-022-04980-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XIZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.3 variant spike (local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XJ6", "evidence_id": "EV-PDB-7XJ6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7XJ6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XJ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 1 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XJ8", "evidence_id": "EV-PDB-7XJ8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7XJ8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XJ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 2 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XJ9", "evidence_id": "EV-PDB-7XJ9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "7XJ9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XJ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of the SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XMZ", "evidence_id": "EV-PDB-7XMZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "7XMZ", "doi": "10.1038/s41421-022-00449-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XMZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three D2 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XNR", "evidence_id": "EV-PDB-7XNR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "7XNR", "doi": "10.1038/s41586-022-04980-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2.13 variant spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XNS", "evidence_id": "EV-PDB-7XNS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "7XNS", "doi": "10.1038/s41586-022-04980-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XNS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2.12.1 variant spike"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XOB", "evidence_id": "EV-PDB-7XOB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7XOB", "doi": "10.1038/s41422-022-00672-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XOB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two mouse ACE2 Bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XOD", "evidence_id": "EV-PDB-7XOD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "7XOD", "doi": "10.1038/s41422-022-00672-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XOD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three JMB2002 Fab Bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "peptide from Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XQS", "evidence_id": "EV-PDB-7XQS-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "7XQS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XQS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of FLA-K*00701/KP-CoV-9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XRP", "evidence_id": "EV-PDB-7XRP-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88}, "provenance": {"deposit_id": "7XRP", "doi": "10.1186/s12951-022-01619-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XRP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (localized refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XRP", "evidence_id": "EV-PDB-7XRP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88}, "provenance": {"deposit_id": "7XRP", "doi": "10.1186/s12951-022-01619-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XRP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (localized refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XST", "evidence_id": "EV-PDB-7XST-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "7XST", "doi": "10.1038/s41421-022-00449-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XST"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron spike glycoprotein in complex with three F61 Fab and three D2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XTZ", "evidence_id": "EV-PDB-7XTZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7XTZ", "doi": "10.1371/journal.ppat.1010583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XTZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XU1", "evidence_id": "EV-PDB-7XU1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7XU1", "doi": "10.1371/journal.ppat.1010583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XU1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-122 Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XU2", "evidence_id": "EV-PDB-7XU2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7XU2", "doi": "10.1371/journal.ppat.1010583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XU2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XU3", "evidence_id": "EV-PDB-7XU3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7XU3", "doi": "10.1371/journal.ppat.1010583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XU3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XU5", "evidence_id": "EV-PDB-7XU5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7XU5", "doi": "10.1371/journal.ppat.1010583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XU5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XU6", "evidence_id": "EV-PDB-7XU6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7XU6", "doi": "10.1371/journal.ppat.1010583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XU6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), incubated in Low pH after 40-Day Storage in PBS, Locked-2 Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XWA", "evidence_id": "EV-PDB-7XWA-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "7XWA", "doi": "10.1016/j.cell.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XWA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BA.4/5 variant spike protein in complex with its receptor ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XXL", "evidence_id": "EV-PDB-7XXL-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.3}, "provenance": {"deposit_id": "7XXL", "doi": "10.1038/s41467-022-33284-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XXL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RBD in complex with Fab14"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XY3", "evidence_id": "EV-PDB-7XY3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "7XY3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XY3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with VHH14"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XY4", "evidence_id": "EV-PDB-7XY4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7XY4", "doi": "10.1007/s11684-025-1128-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XY4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with VHH21"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Spike protein S1 (chains E,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y0C", "evidence_id": "EV-PDB-7Y0C-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.94}, "provenance": {"deposit_id": "7Y0C", "doi": "10.1016/j.celrep.2022.111845", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y0C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of BD55-1403 and SARS-CoV-2 Omicron RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y0N", "evidence_id": "EV-PDB-7Y0N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7Y0N", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y0N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 WT Spike in complex with R15 Fab and P14 Nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y0O", "evidence_id": "EV-PDB-7Y0O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7Y0O", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y0O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Interface of SARS-CoV-2 WT Spike in complex with R15 Fab and P14 Nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y0W", "evidence_id": "EV-PDB-7Y0W-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "7Y0W", "doi": "10.1016/j.celrep.2022.111845", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y0W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local structure of BD55-5514 and BD55-5840 Fab and Omicron BA.1 RBD complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y1Z", "evidence_id": "EV-PDB-7Y1Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7Y1Z", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y1Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.3) in complex with three PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y20", "evidence_id": "EV-PDB-7Y20-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7Y20", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y20"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.3) in complex with two PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y21", "evidence_id": "EV-PDB-7Y21-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7Y21", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.5) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y1Y", "evidence_id": "EV-PDB-7Y1Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7Y1Y", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y1Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.2) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.25, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y0V", "evidence_id": "EV-PDB-7Y0V-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.48}, "provenance": {"deposit_id": "7Y0V", "doi": "10.1016/j.celrep.2022.111845", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y0V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The co-crystal structure of BA.1-RBD with Fab-5549"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XU4", "evidence_id": "EV-PDB-7XU4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7XU4", "doi": "10.1371/journal.ppat.1010583", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XU4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y7K", "evidence_id": "EV-PDB-7Y7K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7Y7K", "doi": "10.1093/procel/pwac042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y7K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD in complex with 1F Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SARS-coV-2 S2 subunit (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y9N", "evidence_id": "EV-PDB-7Y9N-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.885}, "provenance": {"deposit_id": "7Y9N", "doi": "10.1080/22221751.2022.2095308", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y9N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "an engineered 5-helix bundle derived from SARS-CoV-2 S2 in complex with HR2P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2',5HB-H2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y9N", "evidence_id": "EV-PDB-7Y9N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.885}, "provenance": {"deposit_id": "7Y9N", "doi": "10.1080/22221751.2022.2095308", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y9N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "an engineered 5-helix bundle derived from SARS-CoV-2 S2 in complex with HR2P"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y9Z", "evidence_id": "EV-PDB-7Y9Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7Y9Z", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y9Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (one-RBD-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YA0", "evidence_id": "EV-PDB-7YA0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7YA0", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YA0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (S-6P-RRAR)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YA1", "evidence_id": "EV-PDB-7YA1-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "7YA1", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YA1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YBH", "evidence_id": "EV-PDB-7YBH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7YBH", "doi": "10.1016/j.virs.2022.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YBH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 lambda variant spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YBI", "evidence_id": "EV-PDB-7YBI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7YBI", "doi": "10.1016/j.virs.2022.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YBI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Mu variant spike (open state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YBJ", "evidence_id": "EV-PDB-7YBJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "7YBJ", "doi": "10.1016/j.virs.2022.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YBJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Mu variant spike(close state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YBK", "evidence_id": "EV-PDB-7YBK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7YBK", "doi": "10.1016/j.virs.2022.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YBK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 B.1.620 variant spike (open state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YBM", "evidence_id": "EV-PDB-7YBM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "7YBM", "doi": "10.1016/j.virs.2022.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YBM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 C.1.2 variant spike (Close state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YC5", "evidence_id": "EV-PDB-7YC5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7YC5", "doi": "10.1016/j.antiviral.2023.105576", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YC5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,G,J)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YCN", "evidence_id": "EV-PDB-7YCN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7YCN", "doi": "10.1038/s41467-023-35949-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YCN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Spike RBD in complex with IY-2A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YCO", "evidence_id": "EV-PDB-7YCO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "7YCO", "doi": "10.1016/j.antiviral.2023.105738", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YCO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Receptor Binding Domain bound to A6 repebody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YD0", "evidence_id": "EV-PDB-7YD0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.58}, "provenance": {"deposit_id": "7YD0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YD0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 1-RBD up spike trimer complexed with two XG005 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YD1", "evidence_id": "EV-PDB-7YD1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "7YD1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YD1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 Omicron S trimer complexed with XG005"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YDY", "evidence_id": "EV-PDB-7YDY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.75}, "provenance": {"deposit_id": "7YDY", "doi": "10.1038/s41564-022-01235-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YDY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (6P) in complex with 1 R1-32 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YE5", "evidence_id": "EV-PDB-7YE5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.75}, "provenance": {"deposit_id": "7YE5", "doi": "10.1038/s41564-022-01235-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YE5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (6P) in complex with 2 R1-32 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YEG", "evidence_id": "EV-PDB-7YEG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "7YEG", "doi": "10.1038/s41564-022-01235-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YEG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YH6", "evidence_id": "EV-PDB-7YH6-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7YH6", "doi": "10.1038/s41467-023-39890-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YH6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike RBD in complex with neutralizing antibody NIV-8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YHW", "evidence_id": "EV-PDB-7YHW-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09}, "provenance": {"deposit_id": "7YHW", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YHW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YJ3", "evidence_id": "EV-PDB-7YJ3-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7YJ3", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YJ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YOW", "evidence_id": "EV-PDB-7YOW-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7YOW", "doi": "10.1038/s42003-023-04782-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 omicron variant spike receptor-binding domain (RBD) in complex with NCV2SG48 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YQT", "evidence_id": "EV-PDB-7YQT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "7YQT", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YQT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer (1 RBD Up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YQU", "evidence_id": "EV-PDB-7YQU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "7YQU", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YQU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer (3 RBD Down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YQV", "evidence_id": "EV-PDB-7YQV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.58}, "provenance": {"deposit_id": "7YQV", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "pH 5.5 SARS-CoV-2 BA.2.75 S Trimer (1 RBD Up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YQW", "evidence_id": "EV-PDB-7YQW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "7YQW", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YQW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer (3 RBD Down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YKJ", "evidence_id": "EV-PDB-7YKJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7YKJ", "doi": "10.1080/22221751.2022.2146538", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YKJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron RBDs bound with P3E6 Fab (one up and one down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YH7", "evidence_id": "EV-PDB-7YH7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7YH7", "doi": "10.1038/s41467-023-39890-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YH7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with neutralizing antibody NIV-8 (state 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YE9", "evidence_id": "EV-PDB-7YE9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.17}, "provenance": {"deposit_id": "7YE9", "doi": "10.1038/s41564-022-01235-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YE9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YDI", "evidence_id": "EV-PDB-7YDI-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.98}, "provenance": {"deposit_id": "7YDI", "doi": "10.1038/s41564-022-01235-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YDI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YCZ", "evidence_id": "EV-PDB-7YCZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7YCZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YCZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 2-RBD up Spike trimer complexed with three XG005 molecules"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YCY", "evidence_id": "EV-PDB-7YCY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.74}, "provenance": {"deposit_id": "7YCY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YCY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron 1-RBD up Spike trimer complexed with three XG005 molecules"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains D,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YCL", "evidence_id": "EV-PDB-7YCL-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.13}, "provenance": {"deposit_id": "7YCL", "doi": "10.1038/s41467-023-35949-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YCL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Spike RBD in complex with IS-9A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YCK", "evidence_id": "EV-PDB-7YCK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7YCK", "doi": "10.1038/s41467-023-35949-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YCK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Spike RBD in complex with FP-12A Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YBN", "evidence_id": "EV-PDB-7YBN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.82}, "provenance": {"deposit_id": "7YBN", "doi": "10.1016/j.virs.2022.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YBN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 C.1.2 variant spike (Open state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YBL", "evidence_id": "EV-PDB-7YBL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7YBL", "doi": "10.1016/j.virs.2022.11.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YBL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 B.1.620 variant spike (close state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YAD", "evidence_id": "EV-PDB-7YAD-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "7YAD", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YAD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of S309-RBD-RBD-S309 in the S309-bound Omicron spike protein (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y9S", "evidence_id": "EV-PDB-7Y9S-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7Y9S", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y9S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of apo SARS-CoV-2 Omicron spike protein (S-2P-GSAS)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y7J", "evidence_id": "EV-PDB-7Y7J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7Y7J", "doi": "10.1093/procel/pwac042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y7J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S trimer in complex with 1F Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y72", "evidence_id": "EV-PDB-7Y72-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.03}, "provenance": {"deposit_id": "7Y72", "doi": "10.1126/sciadv.ade3470", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y72"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y6N", "evidence_id": "EV-PDB-7Y6N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7Y6N", "doi": "10.1016/j.isci.2023.106955", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y6N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab803"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y6L", "evidence_id": "EV-PDB-7Y6L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7Y6L", "doi": "10.1016/j.isci.2023.106955", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y6L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab816"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z1A", "evidence_id": "EV-PDB-7Z1A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "7Z1A", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z1A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody H11 and F2 bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "IPA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZF3", "evidence_id": "EV-PDB-7ZF3-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15}, "provenance": {"deposit_id": "7ZF3", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZF3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with Omi-3 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZF8", "evidence_id": "EV-PDB-7ZF8-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "7ZF8", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZF8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron BA.2 RBD in complex with COVOX-150 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZF9", "evidence_id": "EV-PDB-7ZF9-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "7ZF9", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZF9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron BA.2 RBD in complex with COVOX-150 Fab (P21)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZFA", "evidence_id": "EV-PDB-7ZFA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.24}, "provenance": {"deposit_id": "7ZFA", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZFA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with Omi-6 and COVOX-150 Fabs"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZF5", "evidence_id": "EV-PDB-7ZF5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.32}, "provenance": {"deposit_id": "7ZF5", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZF5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with Omi-12 and Beta-54 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZF4", "evidence_id": "EV-PDB-7ZF4-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.18}, "provenance": {"deposit_id": "7ZF4", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZF4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with Omi-9 Fab and nanobody F2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZDQ", "evidence_id": "EV-PDB-7ZDQ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7ZDQ", "doi": "10.1371/journal.ppat.1010733", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZDQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZCF", "evidence_id": "EV-PDB-7ZCF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7ZCF", "doi": "10.1016/j.ymthe.2022.09.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZCF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike RBD in complex with the single chain fragment scFv76 (Focused Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZCE", "evidence_id": "EV-PDB-7ZCE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7ZCE", "doi": "10.1016/j.ymthe.2022.09.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZCE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with the single chain fragment scFv76"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3Q9", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZBU", "evidence_id": "EV-PDB-7ZBU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.31}, "provenance": {"deposit_id": "7ZBU", "doi": "10.1016/j.celrep.2022.111276", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS-CoV-2 spike monomer in complex with neutralising antibody P008_60"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z9R", "evidence_id": "EV-PDB-7Z9R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "7Z9R", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z9R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H4 Q98R H100E nanobody complex in 2Up1Down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z9Q", "evidence_id": "EV-PDB-7Z9Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7Z9Q", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z9Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-A10 nanobody complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "KZ0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z8O", "evidence_id": "EV-PDB-7Z8O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.96}, "provenance": {"deposit_id": "7Z8O", "doi": "10.1038/s41467-023-39158-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z8O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 S RBD in complex with a stapled peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z86", "evidence_id": "EV-PDB-7Z86-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7Z86", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z86"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H4 Q98R H100E nanobody complex in 1Up2Down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z85", "evidence_id": "EV-PDB-7Z85-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7Z85", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z85"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-B5 nanobody complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z7X", "evidence_id": "EV-PDB-7Z7X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7Z7X", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z7X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H6 nanobody complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z6V", "evidence_id": "EV-PDB-7Z6V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7Z6V", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z6V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11 nanobody complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "STE", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z3Z", "evidence_id": "EV-PDB-7Z3Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7Z3Z", "doi": "10.1101/2020.08.13.249177", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z3Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Locked Wuhan SARS-CoV2 Prefusion Spike ectodomain with lipid bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG", "NO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z1E", "evidence_id": "EV-PDB-7Z1E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.59}, "provenance": {"deposit_id": "7Z1E", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z1E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody H11-H4 Q98R H100E bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z1D", "evidence_id": "EV-PDB-7Z1D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "7Z1D", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z1D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody H11-H6 bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z1C", "evidence_id": "EV-PDB-7Z1C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "7Z1C", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z1C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody H11-B5 and H11-F2 bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z1B", "evidence_id": "EV-PDB-7Z1B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7Z1B", "doi": "10.1073/pnas.2205412119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z1B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody H11-A10 and F2 bound to RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z0Y", "evidence_id": "EV-PDB-7Z0Y-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "7Z0Y", "doi": "10.1371/journal.ppat.1010465", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THSC20.HVTR04 Fab bound to SARS-CoV-2 Receptor Binding Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EPE", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z0X", "evidence_id": "EV-PDB-7Z0X-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "7Z0X", "doi": "10.1371/journal.ppat.1010465", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THSC20.HVTR26 Fab bound to SARS-CoV-2 Receptor Binding Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YVU", "evidence_id": "EV-PDB-7YVU-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7YVU", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YVU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with mouse ACE2 (local refinement)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YVF", "evidence_id": "EV-PDB-7YVF-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7YVF", "doi": "10.1038/s41467-023-39267-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YVF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron BA.4/5 SARS-CoV-2 S RBD in complex with TH027 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YVE", "evidence_id": "EV-PDB-7YVE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7YVE", "doi": "10.1038/s41467-023-39267-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YVE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron BA.4/5 SARS-CoV-2 S in complex with TH027 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YUE", "evidence_id": "EV-PDB-7YUE-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "7YUE", "doi": "10.1002/pro.4575", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YUE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Epitope-directed anti-SARS CoV 2 scFv engineered against the key spike protein region."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YTN", "evidence_id": "EV-PDB-7YTN-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "7YTN", "doi": "10.3389/fimmu.2022.1049867", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YTN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Alpha RBD in complex with the D27LEY neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YR4", "evidence_id": "EV-PDB-7YR4-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.12}, "provenance": {"deposit_id": "7YR4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YR4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(interface)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YR1", "evidence_id": "EV-PDB-7YR1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.62}, "provenance": {"deposit_id": "7YR1", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YR1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with XG2v024"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YR0", "evidence_id": "EV-PDB-7YR0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.98}, "provenance": {"deposit_id": "7YR0", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YR0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (interface)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YQZ", "evidence_id": "EV-PDB-7YQZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "7YQZ", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YQZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YQY", "evidence_id": "EV-PDB-7YQY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.74}, "provenance": {"deposit_id": "7YQY", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YQY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YQX", "evidence_id": "EV-PDB-7YQX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "7YQX", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YQX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "SARS-CoV2 Spike in 2-up conformation in complex with Fab47 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8A94", "evidence_id": "EV-PDB-8A94-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "8A94", "doi": "10.1016/j.immuni.2022.12.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8A94"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV2 Spike in the 2-up state in complex with Fab47."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R,X,Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BBN", "evidence_id": "EV-PDB-8BBN-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.58}, "provenance": {"deposit_id": "8BBN", "doi": "10.1016/j.celrep.2023.112271", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BBN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Delta-RBD complexed with BA.2-10 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,SARS-CoV-2 spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C8P", "evidence_id": "EV-PDB-8C8P-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "8C8P", "doi": "10.3389/fimmu.2023.1111385", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C8P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein in complex with the 10D12 heavy-chain-only antibody (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C89", "evidence_id": "EV-PDB-8C89-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.41}, "provenance": {"deposit_id": "8C89", "doi": "10.1038/s41467-024-45171-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C89"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike in complex with the 17T2 neutralizing antibody Fab fragment (local refinement of RBD and Fab)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C5R", "evidence_id": "EV-PDB-8C5R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8C5R", "doi": "10.1038/s42003-024-06951-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C5R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron B.1.1.529 2 RBD up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PG0", "PG4", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R,X,Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C3V", "evidence_id": "EV-PDB-8C3V-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74}, "provenance": {"deposit_id": "8C3V", "doi": "10.1016/j.celrep.2023.112271", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C3V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Delta-RBD complexed with BA.2-13 Fab and C1 nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C2R", "evidence_id": "EV-PDB-8C2R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "8C2R", "doi": "10.1016/j.xcrm.2024.101577", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C2R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV2 Omicron BA.1 spike in complex with CAB-A17 antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C1V", "evidence_id": "EV-PDB-8C1V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8C1V", "doi": "10.1038/s41467-023-37290-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C1V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S-trimer (3 RBDs up) bound to TriSb92, fitted into cryo-EM map"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C0Y", "evidence_id": "EV-PDB-8C0Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "8C0Y", "doi": "10.1016/j.xcrm.2024.101577", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV2 Omicron BA.1 RBD in complex with CAB-A17 antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BSF", "evidence_id": "EV-PDB-8BSF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8BSF", "doi": "10.1371/journal.pone.0284173", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BSF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD-beta variant) in complex with 3D2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BSE", "evidence_id": "EV-PDB-8BSE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8BSE", "doi": "10.1371/journal.pone.0284173", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BSE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD) in complex with 1D1 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BON", "evidence_id": "EV-PDB-8BON-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8BON", "doi": "10.1073/pnas.2303292120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BON"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein in complex with the macrocyclic peptide S1B3inL1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PO4", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BH5", "evidence_id": "EV-PDB-8BH5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.38}, "provenance": {"deposit_id": "8BH5", "doi": "10.1038/s41421-022-00482-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BH5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 BA.2.12.1 RBD in complex with Beta-27 Fab and C1 nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BGG", "evidence_id": "EV-PDB-8BGG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.04}, "provenance": {"deposit_id": "8BGG", "doi": "10.1016/j.isci.2023.107085", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BGG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike (Omicron BA.1 variant) in complex with nanobody W25 (map 5, focus refinement on RBD, W25 and adjacent NTD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BG8", "evidence_id": "EV-PDB-8BG8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.64}, "provenance": {"deposit_id": "8BG8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BG8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein in complex with pT1696 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BG6", "evidence_id": "EV-PDB-8BG6-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.11}, "provenance": {"deposit_id": "8BG6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BG6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein in complex with pT1644 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BG5", "evidence_id": "EV-PDB-8BG5-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "8BG5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BG5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 S RBD in complex with pT1631 scFV"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BG4", "evidence_id": "EV-PDB-8BG4-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "8BG4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BG4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 S RBD in complex with pT1611 scFV"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BG3", "evidence_id": "EV-PDB-8BG3-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8BG3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 S RBD in complex with pT1610 scFV"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BG2", "evidence_id": "EV-PDB-8BG2-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8BG2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BG2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 S RBD in complex with pT1580 scFV"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,F,I,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BG1", "evidence_id": "EV-PDB-8BG1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88}, "provenance": {"deposit_id": "8BG1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BG1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 S RBD in complex with pT1511 scFV"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BEV", "evidence_id": "EV-PDB-8BEV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.92}, "provenance": {"deposit_id": "8BEV", "doi": "10.1016/j.isci.2023.107085", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BEV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike (HexaPro variant) in complex with nanobody W25 (map 3, focus refinement on RBD, W25 and adjacent NTD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BEC", "evidence_id": "EV-PDB-8BEC-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8BEC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 S RBD in complex with pT1375 scFV"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BE1", "evidence_id": "EV-PDB-8BE1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.98}, "provenance": {"deposit_id": "8BE1", "doi": "10.1038/s41587-024-02346-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BE1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 RBD in complex with a Fab fragment of a neutralising antibody mRBD2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BCZ", "evidence_id": "EV-PDB-8BCZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8BCZ", "doi": "10.1016/j.celrep.2023.112271", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BCZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta-RBD complexed with Fabs BA.2-36, BA.2-23, EY6A and COVOX-45"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ASY", "evidence_id": "EV-PDB-8ASY-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "8ASY", "doi": "10.1016/j.celrep.2022.111903", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ASY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron BA.2.75 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AQW", "evidence_id": "EV-PDB-8AQW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8AQW", "doi": "10.1371/journal.ppat.1011206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AQW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.4/5 SARS-CoV-2 Spike bound to mouse ACE2 (local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AQV", "evidence_id": "EV-PDB-8AQV-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "8AQV", "doi": "10.1371/journal.ppat.1011206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.12.1 SARS-CoV-2 Spike bound to mouse ACE2 (local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AQU", "evidence_id": "EV-PDB-8AQU-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "8AQU", "doi": "10.1371/journal.ppat.1011206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AQU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.1 SARS-CoV-2 Spike bound to mouse ACE2 (local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AQT", "evidence_id": "EV-PDB-8AQT-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "8AQT", "doi": "10.1371/journal.ppat.1011206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AQT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Beta SARS-CoV-2 Spike bound to mouse ACE2 (local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AJL", "evidence_id": "EV-PDB-8AJL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8AJL", "doi": "10.1038/s41467-023-42200-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AJL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the Ancestral Scaffold Antigen-6 of Coronavirus Spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AJA", "evidence_id": "EV-PDB-8AJA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "8AJA", "doi": "10.1038/s41467-023-42200-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AJA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the Ancestral Scaffold Antigen-5 of Coronavirus Spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["29N"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AAA", "evidence_id": "EV-PDB-8AAA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8AAA", "doi": "10.1038/s41467-023-39158-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 S RBD in complex with a stapled peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "SARS-CoV2 spike 1-up conformation in complex with Fab47 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8A99", "evidence_id": "EV-PDB-8A99-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8A99", "doi": "10.1016/j.immuni.2022.12.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8A99"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS Cov2 Spike in 1-up conformation complex with Fab47"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8A96", "evidence_id": "EV-PDB-8A96-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8A96", "doi": "10.1016/j.immuni.2022.12.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8A96"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS Cov2 Spike RBD in complex with Fab47"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "SARS-CoV2 Trimeric Spike in 1-up conformation in complex with three Fab47 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8A95", "evidence_id": "EV-PDB-8A95-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.64}, "provenance": {"deposit_id": "8A95", "doi": "10.1016/j.immuni.2022.12.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8A95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS Cov2 Spike RBD in complex with Fab47"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "IPA", "NAG", "PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZXU", "evidence_id": "EV-PDB-7ZXU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.89}, "provenance": {"deposit_id": "7ZXU", "doi": "10.1016/j.cell.2022.06.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZXU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron BA.4/5 RBD in complex with Beta-27 Fab and C1 nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZSS", "evidence_id": "EV-PDB-7ZSS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.63}, "provenance": {"deposit_id": "7ZSS", "doi": "10.1038/s41586-023-05993-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZSS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of D614 spike in complex with de novo designed binder"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZSD", "evidence_id": "EV-PDB-7ZSD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7ZSD", "doi": "10.1038/s41586-023-05993-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZSD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of omicron spike in complex with de novo designed binder, local"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Envelope glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZRV", "evidence_id": "EV-PDB-7ZRV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7ZRV", "doi": "10.1038/s41586-023-05993-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZRV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of omicron spike in complex with de novo designed binder, full map"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZRC", "evidence_id": "EV-PDB-7ZRC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7ZRC", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZRC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZR9", "evidence_id": "EV-PDB-7ZR9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7ZR9", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZR9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "OMI-2 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZR8", "evidence_id": "EV-PDB-7ZR8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7ZR8", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZR8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE RBD (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZR7", "evidence_id": "EV-PDB-7ZR7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7ZR7", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZR7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "OMI-42 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZR2", "evidence_id": "EV-PDB-7ZR2-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "7ZR2", "doi": "10.1016/j.ijbiomac.2022.10.031", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZR2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a chimeric protein mimic of SARS-CoV-2 Spike HR1 in complex with HR2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2',Chimeric protein mimic of SARS-CoV-2 Spike HR1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZR2", "evidence_id": "EV-PDB-7ZR2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "7ZR2", "doi": "10.1016/j.ijbiomac.2022.10.031", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZR2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a chimeric protein mimic of SARS-CoV-2 Spike HR1 in complex with HR2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZJL", "evidence_id": "EV-PDB-7ZJL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7ZJL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZJL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta SARS-CoV-2 spike protein in complex with REGN10987 Fab homologue."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZFE", "evidence_id": "EV-PDB-7ZFE-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "7ZFE", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZFE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with Omi-32 Fab and nanobody C1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZFD", "evidence_id": "EV-PDB-7ZFD-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "7ZFD", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZFD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with Omi-25 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZFC", "evidence_id": "EV-PDB-7ZFC-6", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7ZFC", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZFC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Beta RBD in complex with nanobody C1, Omi-18 and Omi-31 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZFB", "evidence_id": "EV-PDB-7ZFB-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "7ZFB", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZFB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron RBD in complex with nanobody C1, Omi-18 and Omi-31 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R,X,Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CBD", "evidence_id": "EV-PDB-8CBD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "8CBD", "doi": "10.1038/s41467-024-47393-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CBD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Delta-RBD complexed with BA.4/5-1 and EY6A Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CBE", "evidence_id": "EV-PDB-8CBE-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "8CBE", "doi": "10.1038/s41467-024-47393-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CBE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Delta-RBD complexed with BA.4/5-2 and Beta-49 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "SO4", "branched: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CBF", "evidence_id": "EV-PDB-8CBF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33}, "provenance": {"deposit_id": "8CBF", "doi": "10.1038/s41467-024-47393-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CBF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Delta-RBD complexed with Omi-42 and Beta-49 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CII", "evidence_id": "EV-PDB-8CII-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8CII", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CII"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Delta-RBD complex with BA.2-07 fab, SARS1-34 fab and C1 nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CIM", "evidence_id": "EV-PDB-8CIM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8CIM", "doi": "10.21203/rs.3.rs-2684849/v1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CIM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2-07 FAB IN COMPLEX WITH SARS-COV-2 BA.2.12.1 SPIKE GLYCOPROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CIN", "evidence_id": "EV-PDB-8CIN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8CIN", "doi": "10.1038/s41467-024-46982-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CIN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.4/5-5 FAB IN COMPLEX WITH SARS-COV-2 BA.4 SPIKE GLYCOPROTEIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DHL", "EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CMB", "evidence_id": "EV-PDB-8CMB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "8CMB", "doi": "10.1016/j.celrep.2023.112827", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CMB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S486-505"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C,F,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CMD", "evidence_id": "EV-PDB-8CMD-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.54}, "provenance": {"deposit_id": "8CMD", "doi": "10.1016/j.celrep.2023.112827", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CMD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S761-775"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DHL", "EDO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CMH", "evidence_id": "EV-PDB-8CMH-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.64}, "provenance": {"deposit_id": "8CMH", "doi": "10.1016/j.celrep.2023.112827", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CMH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S486-505"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C,F,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CMI", "evidence_id": "EV-PDB-8CMI-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8CMI", "doi": "10.1016/j.celrep.2023.112827", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CMI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S761-775"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CSA", "evidence_id": "EV-PDB-8CSA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "8CSA", "doi": "10.1126/science.abi6226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CSA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 3-RBD-Down conformation (S-GSAS-D614G-K417N-E484K-N501Y)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CWI", "evidence_id": "EV-PDB-8CWI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.873}, "provenance": {"deposit_id": "8CWI", "doi": "10.1073/pnas.2417544121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CWI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fab arm of antibody 10G4 bound to CoV-2 receptor binding domain (RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains G,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CWJ", "evidence_id": "EV-PDB-8CWJ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.449}, "provenance": {"deposit_id": "8CWJ", "doi": "10.1073/pnas.2417544121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fab arms of antibodies 4C12-B12 and CR3022 bound to pangolin receptor binding domain (pRBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CWK", "evidence_id": "EV-PDB-8CWK-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.368}, "provenance": {"deposit_id": "8CWK", "doi": "10.1073/pnas.2417544121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CWK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fab arm of antibodies 4G1-C2 and 10G4 bound to CoV-2 receptor binding domain (RBD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 10.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CWU", "evidence_id": "EV-PDB-8CWU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.71}, "provenance": {"deposit_id": "8CWU", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CWU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing nanobody 1-21"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CXN", "evidence_id": "EV-PDB-8CXN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8CXN", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CXN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-57"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CXQ", "evidence_id": "EV-PDB-8CXQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8CXQ", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CXQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CY9", "evidence_id": "EV-PDB-8CY9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8CY9", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CY9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-23"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYA", "evidence_id": "EV-PDB-8CYA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8CYA", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-67"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AH2", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-alpha-L-fucopyranose-(1-6)-[beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYB", "evidence_id": "EV-PDB-8CYB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8CYB", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYC", "evidence_id": "EV-PDB-8CYC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8CYC", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYD", "evidence_id": "EV-PDB-8CYD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8CYD", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-45"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' HR2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CZI", "evidence_id": "EV-PDB-8CZI-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.22}, "provenance": {"deposit_id": "8CZI", "doi": "10.1073/pnas.2210990119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Scaffolded Spike protein S2' HR1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CZI", "evidence_id": "EV-PDB-8CZI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.22}, "provenance": {"deposit_id": "8CZI", "doi": "10.1073/pnas.2210990119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D0Z", "evidence_id": "EV-PDB-8D0Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8D0Z", "doi": "10.1172/JCI166844", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D0Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 fusion peptide (chains F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D36", "evidence_id": "EV-PDB-8D36-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "8D36", "doi": "10.1126/science.abq3773", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D36"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 fusion peptide in complex with neutralizing antibody COV44-62"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D48", "evidence_id": "EV-PDB-8D48-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8D48", "doi": "10.1126/sciimmunol.ade0958", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D48"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "sd1.040 Fab in complex with SARS-CoV-2 Spike 2P glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D55", "evidence_id": "EV-PDB-8D55-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8D55", "doi": "10.1038/s41594-023-01023-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D55"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Closed state of SARS-CoV-2 BA.2 variant spike protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D5A", "evidence_id": "EV-PDB-8D5A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8D5A", "doi": "10.1038/s41594-023-01023-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D5A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Middle state of SARS-CoV-2 BA.2 variant spike protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 fusion peptide (chains H,J,K,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8D6Z", "evidence_id": "EV-PDB-8D6Z-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8D6Z", "doi": "10.1126/science.abq3773", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8D6Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike stem fusion peptide in complex with neutralizing antibody COV91-27"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYJ", "evidence_id": "EV-PDB-8CYJ-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8CYJ", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RBD of SARS-CoV-2 Spike protein in complex with pan-sarbecovirus nanobodies 2-10, 2-67, 2-62 and 1-25"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CY7", "evidence_id": "EV-PDB-8CY7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8CY7", "doi": "10.1016/j.celrep.2022.111004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CY7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DZI", "evidence_id": "EV-PDB-8DZI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8DZI", "doi": "10.1038/s41392-023-01509-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody MB.02"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DMA", "evidence_id": "EV-PDB-8DMA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "8DMA", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DMA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM9", "evidence_id": "EV-PDB-8DM9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "8DM9", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM7", "evidence_id": "EV-PDB-8DM7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.49}, "provenance": {"deposit_id": "8DM7", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with mouse ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM4", "evidence_id": "EV-PDB-8DM4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "8DM4", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM3", "evidence_id": "EV-PDB-8DM3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.37}, "provenance": {"deposit_id": "8DM3", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM2", "evidence_id": "EV-PDB-8DM2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "8DM2", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein (focused refinement of NTD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM1", "evidence_id": "EV-PDB-8DM1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8DM1", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM0", "evidence_id": "EV-PDB-8DM0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.21}, "provenance": {"deposit_id": "8DM0", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G spike protein in complex with VH ab6 (focused refinement of NTD and VH ab6)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLZ", "evidence_id": "EV-PDB-8DLZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "8DLZ", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G spike protein in complex with VH ab6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLY", "evidence_id": "EV-PDB-8DLY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8DLY", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with VH ab6 (focused refinement of NTD and VH ab6)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLX", "evidence_id": "EV-PDB-8DLX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "8DLX", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with VH ab6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLW", "evidence_id": "EV-PDB-8DLW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.16}, "provenance": {"deposit_id": "8DLW", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with Fab S2M11"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLV", "evidence_id": "EV-PDB-8DLV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "8DLV", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLU", "evidence_id": "EV-PDB-8DLU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "8DLU", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLT", "evidence_id": "EV-PDB-8DLT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "8DLT", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLS", "evidence_id": "EV-PDB-8DLS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "8DLS", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLR", "evidence_id": "EV-PDB-8DLR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "8DLR", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with Fab 4-8 (focused refinement of NTD and 4-8)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLQ", "evidence_id": "EV-PDB-8DLQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8DLQ", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLP", "evidence_id": "EV-PDB-8DLP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.64}, "provenance": {"deposit_id": "8DLP", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLO", "evidence_id": "EV-PDB-8DLO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "8DLO", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLN", "evidence_id": "EV-PDB-8DLN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8DLN", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLM", "evidence_id": "EV-PDB-8DLM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "8DLM", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLL", "evidence_id": "EV-PDB-8DLL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "8DLL", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EPN", "evidence_id": "EV-PDB-8EPN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8EPN", "doi": "10.1126/sciadv.adg0330", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EPN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike trimer S2D14 in the 3-RBD Down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,E,G,K)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F2J", "evidence_id": "EV-PDB-8F2J-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "8F2J", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F2J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of antibody WRAIR-2134 in complex with SARS-CoV-2 receptor binding domain"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FXC", "evidence_id": "EV-PDB-8FXC-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8FXC", "doi": "10.1038/s41586-023-06487-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BCN", "GOL", "SO4", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,D,G,J)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GB5", "evidence_id": "EV-PDB-8GB5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "8GB5", "doi": "10.1126/scitranslmed.adg7404", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GB5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 25F9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GB0", "evidence_id": "EV-PDB-8GB0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "8GB0", "doi": "10.1101/2023.03.30.535005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike H655Y variant, One RBD Open"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G7C", "evidence_id": "EV-PDB-8G7C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "8G7C", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G7C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "local refinement of SARS-CoV-2 spike/Nb4 complex with 2 RBDs up and 3 Nb4 bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G7B", "evidence_id": "EV-PDB-8G7B-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8G7B", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G7B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb3 complex with 1 RBD up and 2 Nb3 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G7A", "evidence_id": "EV-PDB-8G7A-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8G7A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G7A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb3 complex with 2 RBDs up and 3 Nb3 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G79", "evidence_id": "EV-PDB-8G79-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.1}, "provenance": {"deposit_id": "8G79", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G79"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 spike/nanobody mixture complex around RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G78", "evidence_id": "EV-PDB-8G78-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8G78", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G78"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 spike/nanobody mixture complex around NTD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G77", "evidence_id": "EV-PDB-8G77-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8G77", "doi": "10.1371/journal.ppat.1012493", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G77"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb6 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G76", "evidence_id": "EV-PDB-8G76-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8G76", "doi": "10.1371/journal.ppat.1012493", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G76"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb5 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G75", "evidence_id": "EV-PDB-8G75-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8G75", "doi": "10.1128/jvi.01448-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G75"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb4 complex with 2 RBDs up and 3 Nb4 bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G74", "evidence_id": "EV-PDB-8G74-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8G74", "doi": "10.1128/jvi.01448-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G74"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb3 complex with 1 RBD up and 2 Nb3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G73", "evidence_id": "EV-PDB-8G73-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8G73", "doi": "10.1128/jvi.01448-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G73"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb3 complex with 2 RBDs up and 3 Nb3 bound at 2.5 A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G72", "evidence_id": "EV-PDB-8G72-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.6}, "provenance": {"deposit_id": "8G72", "doi": "10.1128/jvi.01448-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G72"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/Nb2 complex with 1 RBD up (local refinement at 5.6 A)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G71", "evidence_id": "EV-PDB-8G71-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8G71", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G71"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike/Nb2 complex with 1 RBD up"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G70", "evidence_id": "EV-PDB-8G70-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8G70", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G70"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike/nanobody mixture complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FU9", "evidence_id": "EV-PDB-8FU9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "8FU9", "doi": "10.1371/journal.ppat.1011308", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FU9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Covid Spike variant deltaN25 with one erect RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FU8", "evidence_id": "EV-PDB-8FU8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "8FU8", "doi": "10.1371/journal.ppat.1011308", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FU8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Covid Spike variant deltaN135 with one erect RBD"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MLI", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,D,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FHY", "evidence_id": "EV-PDB-8FHY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.53}, "provenance": {"deposit_id": "8FHY", "doi": "10.1038/s41467-023-44265-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5021"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FEZ", "evidence_id": "EV-PDB-8FEZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "8FEZ", "doi": "10.1038/s41467-024-45480-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FEZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prefusion-stabilized SARS-CoV-2 spike protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FAH", "evidence_id": "EV-PDB-8FAH-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.22}, "provenance": {"deposit_id": "8FAH", "doi": "10.1016/j.str.2023.11.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FAH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with SARS-CoV-2 reactive human antibody CR3022"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' 42G (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FA2", "evidence_id": "EV-PDB-8FA2-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "8FA2", "doi": "10.1073/pnas.2300360120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FA2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Scaffolded Spike protein S2' HR1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FA2", "evidence_id": "EV-PDB-8FA2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "8FA2", "doi": "10.1073/pnas.2300360120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FA2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' HR2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FA1", "evidence_id": "EV-PDB-8FA1-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "8FA1", "doi": "10.1073/pnas.2300360120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FA1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F4P", "evidence_id": "EV-PDB-8F4P-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8F4P", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F4P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein trimer (down conformation) bound with a nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F2X", "evidence_id": "EV-PDB-8F2X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.501}, "provenance": {"deposit_id": "8F2X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F2X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of antibody WRAIR-2123 in complex with SARS-CoV-2 receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F0I", "evidence_id": "EV-PDB-8F0I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8F0I", "doi": "10.1016/j.isci.2023.108009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F0I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody COVA309-22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F0H", "evidence_id": "EV-PDB-8F0H-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "8F0H", "doi": "10.1016/j.celrep.2023.112421", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F0H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike with antibody Fabs 2A10 and 1H2 (Local refinement of the RBD and Fabs 1H2 and 2A10)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F0G", "evidence_id": "EV-PDB-8F0G-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "8F0G", "doi": "10.1016/j.celrep.2023.112421", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F0G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 Omicron BA.1 spike in complex with antibody Fab 1C3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EYH", "evidence_id": "EV-PDB-8EYH-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "8EYH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein bound with a nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EYG", "evidence_id": "EV-PDB-8EYG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "8EYG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EYG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein complexed with two nanobodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ERR", "evidence_id": "EV-PDB-8ERR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8ERR", "doi": "10.1126/science.adc9127", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ERR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ERQ", "evidence_id": "EV-PDB-8ERQ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8ERQ", "doi": "10.1126/science.adc9127", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ERQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EQF", "evidence_id": "EV-PDB-8EQF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "8EQF", "doi": "10.1128/mbio.02477-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EQF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryoEM structure of a broadly neutralizing anti-SARS-CoV-2 antibody STI-9167"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EOO", "evidence_id": "EV-PDB-8EOO-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8EOO", "doi": "10.1128/jvi.01596-22", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EOO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibodies WRAIR-2063 and WRAIR-2151"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Clientized spike tail heptapeptide (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ENX", "evidence_id": "EV-PDB-8ENX-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "8ENX", "doi": "10.1038/s41467-023-44076-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ENX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of beta'-COPI-WD40 domain Y33A mutant in complex with SARS-CoV-2 clientized spike tail heptapeptide."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Clientized spike tail peptide (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ENW", "evidence_id": "EV-PDB-8ENW-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "8ENW", "doi": "10.1038/s41467-023-44076-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ENW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of beta'-COPI-WD40 domain in complex with SARS-CoV-2 clientized spike tail heptapeptide."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "spike tail hepta-peptide (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ENS", "evidence_id": "EV-PDB-8ENS-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.45}, "provenance": {"deposit_id": "8ENS", "doi": "10.1038/s41467-023-44076-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ENS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of beta'-COPI-WD40 domain in complex with SARS-CoV-2 spike tail hepta-peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELQ", "evidence_id": "EV-PDB-8ELQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.21}, "provenance": {"deposit_id": "8ELQ", "doi": "10.1073/pnas.2216612120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-255"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELP", "evidence_id": "EV-PDB-8ELP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "8ELP", "doi": "10.1073/pnas.2216612120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-240"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELO", "evidence_id": "EV-PDB-8ELO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "8ELO", "doi": "10.1073/pnas.2216612120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-225"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELJ", "evidence_id": "EV-PDB-8ELJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8ELJ", "doi": "10.1371/journal.ppat.1011532", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike glycoprotein in complex with the ICO-hu23 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ELH", "evidence_id": "EV-PDB-8ELH-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "8ELH", "doi": "10.1038/s41586-023-06331-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ELH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANQF from SARS-CoV-2 virus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GJM", "evidence_id": "EV-PDB-8GJM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8GJM", "doi": "10.1002/jmv.28673", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GJM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "17b10 fab in complex with full-length SARS-CoV-2 Spike G614 trimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GJN", "evidence_id": "EV-PDB-8GJN-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8GJN", "doi": "10.1002/jmv.28673", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GJN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "17B10 fab in complex with up-RBD of SARS-CoV-2 Spike G614 trimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GOU", "evidence_id": "EV-PDB-8GOU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8GOU", "doi": "10.1038/s41467-023-39267-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron BA.4/5 SARS-CoV-2 S in complex with TH003 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GS9", "evidence_id": "EV-PDB-8GS9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "8GS9", "doi": "10.1016/j.celrep.2023.112532", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GS9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2 spike RBD in complex bound with VacBB-551"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GX9", "evidence_id": "EV-PDB-8GX9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.01}, "provenance": {"deposit_id": "8GX9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD with P2C-1F11 and P2B-1G5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H91", "evidence_id": "EV-PDB-8H91-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "8H91", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H91"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with nanobody N19"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HEC", "evidence_id": "EV-PDB-8HEC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8HEC", "doi": "10.1016/j.bbrc.2023.04.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HEB", "evidence_id": "EV-PDB-8HEB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "8HEB", "doi": "10.1016/j.bbrc.2023.04.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HCB", "evidence_id": "EV-PDB-8HCB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.18}, "provenance": {"deposit_id": "8HCB", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HCB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (2 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HCA", "evidence_id": "EV-PDB-8HCA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.35}, "provenance": {"deposit_id": "8HCA", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HCA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC9", "evidence_id": "EV-PDB-8HC9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.03}, "provenance": {"deposit_id": "8HC9", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (3 RBD down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC8", "evidence_id": "EV-PDB-8HC8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "8HC8", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with YB13-292 Fab, focused refinement of Fab region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC7", "evidence_id": "EV-PDB-8HC7-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.54}, "provenance": {"deposit_id": "8HC7", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) complex with YB9-258 Fab, focused refinement of RBD-dimer region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC7", "evidence_id": "EV-PDB-8HC7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.54}, "provenance": {"deposit_id": "8HC7", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) complex with YB9-258 Fab, focused refinement of RBD-dimer region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC6", "evidence_id": "EV-PDB-8HC6-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.69}, "provenance": {"deposit_id": "8HC6", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with YB9-258 Fab, focused refinement of Fab region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC6", "evidence_id": "EV-PDB-8HC6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.69}, "provenance": {"deposit_id": "8HC6", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with YB9-258 Fab, focused refinement of Fab region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC5", "evidence_id": "EV-PDB-8HC5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "8HC5", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 wildtype S1 in complex with YB9-258 Fab and R1-32 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC4", "evidence_id": "EV-PDB-8HC4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54}, "provenance": {"deposit_id": "8HC4", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 wildtype spike trimer (6P) in complex with 3 YB9-258 Fabs and 3 R1-32 Fabs (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC3", "evidence_id": "EV-PDB-8HC3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.35}, "provenance": {"deposit_id": "8HC3", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 2 YB9-258 Fabs (2 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HC2", "evidence_id": "EV-PDB-8HC2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.21}, "provenance": {"deposit_id": "8HC2", "doi": "10.1038/s41467-023-36761-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HC2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 1 YB9-258 Fab (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H7Z", "evidence_id": "EV-PDB-8H7Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "8H7Z", "doi": "10.1038/s41467-024-45050-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H7Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 BA.2 RBD in complex with BA7535 fab (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H7L", "evidence_id": "EV-PDB-8H7L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.44}, "provenance": {"deposit_id": "8H7L", "doi": "10.1038/s41467-024-45050-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H7L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of SARS-CoV-2 BA.2 Spike protein in complex with BA7535"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H6F", "evidence_id": "EV-PDB-8H6F-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8H6F", "doi": "10.1016/j.antiviral.2023.105738", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H6F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike protein in complex with A6 repebody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H5U", "evidence_id": "EV-PDB-8H5U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.401}, "provenance": {"deposit_id": "8H5U", "doi": "10.1371/journal.ppat.1011804", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H5U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-021"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H5T", "evidence_id": "EV-PDB-8H5T-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "8H5T", "doi": "10.1371/journal.ppat.1011804", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H5T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-015"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H5C", "evidence_id": "EV-PDB-8H5C-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8H5C", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H5C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 Omicron BA.2.75 RBD in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H3N", "evidence_id": "EV-PDB-8H3N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.73}, "provenance": {"deposit_id": "8H3N", "doi": "10.1128/jvi.00286-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H3N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Conformation 2 of SARS-CoV-2 Omicron BA.1 Variant Spike protein complexed with MO1 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H3M", "evidence_id": "EV-PDB-8H3M-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.48}, "provenance": {"deposit_id": "8H3M", "doi": "10.1128/jvi.00286-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H3M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Conformation 1 of SARS-CoV-2 Omicron BA.1 Variant Spike protein complexed with MO1 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "Q83"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H3E", "evidence_id": "EV-PDB-8H3E-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "8H3E", "doi": "10.1021/acscentsci.2c01190", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H3E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex structure of a small molecule (SPC-14) bound SARS-CoV-2 spike protein, closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H3D", "evidence_id": "EV-PDB-8H3D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "8H3D", "doi": "10.1021/acscentsci.2c01190", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H3D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of apo SARS-CoV-2 spike protein with one RBD up"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H08", "evidence_id": "EV-PDB-8H08-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8H08", "doi": "10.1038/s41467-023-37926-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H08"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H07", "evidence_id": "EV-PDB-8H07-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8H07", "doi": "10.1038/s41467-023-37926-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H07"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.4 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H06", "evidence_id": "EV-PDB-8H06-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "8H06", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H06"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with human ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H01", "evidence_id": "EV-PDB-8H01-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8H01", "doi": "10.1038/s42003-023-04759-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H01"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in class 2 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H00", "evidence_id": "EV-PDB-8H00-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "8H00", "doi": "10.1038/s42003-023-04759-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H00"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in the class 1 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GZZ", "evidence_id": "EV-PDB-8GZZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "8GZZ", "doi": "10.1038/s42003-023-04759-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GZZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GTQ", "evidence_id": "EV-PDB-8GTQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8GTQ", "doi": "10.1038/s41421-023-00535-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GTQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of Omicron BA.5 S protein in complex with S2L20"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GTP", "evidence_id": "EV-PDB-8GTP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8GTP", "doi": "10.1038/s41421-023-00535-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GTP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of Omicron BA.5 S protein in complex with XGv289"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GTO", "evidence_id": "EV-PDB-8GTO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8GTO", "doi": "10.1038/s41421-023-00535-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GTO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-EM structure of Omicron BA.5 S protein in complex with XGv282"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GS6", "evidence_id": "EV-PDB-8GS6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "8GS6", "doi": "10.1016/j.chom.2022.10.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GS6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 BA.2.75 spike glycoprotein (closed state 1)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GPY", "evidence_id": "EV-PDB-8GPY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "8GPY", "doi": "10.1038/s41467-023-39267-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GPY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Omicron BA.4/5 RBD in complex with a neutralizing antibody scFv"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GON", "evidence_id": "EV-PDB-8GON-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.601}, "provenance": {"deposit_id": "8GON", "doi": "10.1016/j.jbc.2023.103035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GON"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-T1006I-HLA-A2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PG4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GOM", "evidence_id": "EV-PDB-8GOM-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.783}, "provenance": {"deposit_id": "8GOM", "doi": "10.1016/j.jbc.2023.103035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GOM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-HLA-A2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GNH", "evidence_id": "EV-PDB-8GNH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.74}, "provenance": {"deposit_id": "8GNH", "doi": "10.1016/j.ijbiomac.2022.12.120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GNH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex structure of BD-218 and Spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GF2", "evidence_id": "EV-PDB-8GF2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.851}, "provenance": {"deposit_id": "8GF2", "doi": "10.1126/scisignal.abk3516", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GF2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies eCR3022.20 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GDR", "evidence_id": "EV-PDB-8GDR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8GDR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21B10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "GLY", "GOL", "NAG", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GB8", "evidence_id": "EV-PDB-8GB8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8GB8", "doi": "10.1126/scitranslmed.adg7404", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GB8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 BA.2 receptor binding domain in complex with neutralizing antibody 20A7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GB7", "evidence_id": "EV-PDB-8GB7-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "8GB7", "doi": "10.1126/scitranslmed.adg7404", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GB7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 20A7"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HED", "evidence_id": "EV-PDB-8HED-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.59}, "provenance": {"deposit_id": "8HED", "doi": "10.1016/j.bbrc.2023.04.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HED"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HES", "evidence_id": "EV-PDB-8HES-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8HES", "doi": "10.1038/s41467-023-39890-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD and NIV-10 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HPV", "evidence_id": "EV-PDB-8HPV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "8HPV", "doi": "10.1038/s41421-023-00585-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HPV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron Prototype S-trimer in complex with fab L4.65 and L5.34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HR2", "evidence_id": "EV-PDB-8HR2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "8HR2", "doi": "10.1016/j.jsb.2023.107996", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HR2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ternary Crystal Complex Structure of RBD with NB1B5 and NB1C6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,K,T)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HRD", "evidence_id": "EV-PDB-8HRD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "8HRD", "doi": "10.1073/pnas.2314193120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HRD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant in complex with IMCAS74 Fab and W14 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "THR-PRO-GLN-SER-ALA-PRO-HIS-GLY-VAL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HSW", "evidence_id": "EV-PDB-8HSW-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.03}, "provenance": {"deposit_id": "8HSW", "doi": "10.1038/s42003-024-06292-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HSW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF BAT MHC CLASS I MYLU-B-67 FOR 2.1 ANGSTROM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "THR-PRO-GLN-SER-ALA-PRO-HIS-GLY-VAL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HT1", "evidence_id": "EV-PDB-8HT1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "8HT1", "doi": "10.1038/s42003-024-06292-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HT1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF A MUTANT MYLU-B-67 FOR 2.4 ANGSTROM, 52M 53Q 54Q 55P 56W DELETED"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GLU-PRO-GLN-SER-ALA-PRO-HIS-GLY-VAL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HT9", "evidence_id": "EV-PDB-8HT9-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8HT9", "doi": "10.1038/s42003-024-06292-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HT9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF BAT MHC CLASS I MYLU-B-67 FOR 2.2 ANGSTROM"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I5I", "evidence_id": "EV-PDB-8I5I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "8I5I", "doi": "10.1038/s42003-023-04782-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I5I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 delta variant spike receptor-binding domain (RBD) in complex with NCV2SG53 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9G", "evidence_id": "EV-PDB-8I9G-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8I9G", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-RBD (Omicron BF.7) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9F", "evidence_id": "EV-PDB-8I9F-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8I9F", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-RBD (Omicron BA.2.75) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9D", "evidence_id": "EV-PDB-8I9D-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "8I9D", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron XBB.1) in complex with PD of ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9B", "evidence_id": "EV-PDB-8I9B-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8I9B", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.2.75) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I4H", "evidence_id": "EV-PDB-8I4H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.81}, "provenance": {"deposit_id": "8I4H", "doi": "10.1038/s41392-023-01534-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I4H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron spike variant BA.1 with Bn03"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I4G", "evidence_id": "EV-PDB-8I4G-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.68}, "provenance": {"deposit_id": "8I4G", "doi": "10.1038/s41392-023-01534-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I4G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron spike variant BQ.1.1 with n3130v-Fc"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PHE-PRO-GLN-SER-ALA-PRO-HIS-GLY-VAL (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HSO", "evidence_id": "EV-PDB-8HSO-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8HSO", "doi": "10.1038/s42003-024-06292-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HSO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF A MUTANT MYLU-B-67 FOR 2.2 ANGSTROM, 52M 53Q 54Q 55P 56W DELETED"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SARS-CoV-2 Spike KxHxx motif (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HQT", "evidence_id": "EV-PDB-8HQT-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "8HQT", "doi": "10.1016/j.apsb.2023.04.007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HQT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The complex structure of COPI cargo sorting module with SARS-CoV-2 Spike KxHxx sorting motif"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HQ7", "evidence_id": "EV-PDB-8HQ7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8HQ7", "doi": "10.1038/s41421-023-00585-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HQ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron Prototype RBD in complex with fab L4.65 and L5.34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HPQ", "evidence_id": "EV-PDB-8HPQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "8HPQ", "doi": "10.1038/s41421-023-00585-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.4 S-trimer in complex with fab L4.65 and L5.34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HP9", "evidence_id": "EV-PDB-8HP9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "8HP9", "doi": "10.1038/s41421-023-00585-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HP9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 S-trimer in complex with fab L4.65 and L5.34"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HHZ", "evidence_id": "EV-PDB-8HHZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.28}, "provenance": {"deposit_id": "8HHZ", "doi": "10.1038/s41467-023-35949-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 Spike in complex with IY-2A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HHY", "evidence_id": "EV-PDB-8HHY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8HHY", "doi": "10.1038/s41467-023-35949-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta Spike in complex with IS-9A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HFZ", "evidence_id": "EV-PDB-8HFZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "8HFZ", "doi": "10.1128/jvi.00505-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HFZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with white-tailed deer ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IF2", "evidence_id": "EV-PDB-8IF2-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "8IF2", "doi": "10.1038/s41467-023-38188-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IF2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BQ.1.1 variant spike protein in complex with its receptor ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IFZ", "evidence_id": "EV-PDB-8IFZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "8IFZ", "doi": "10.1128/jvi.00505-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IFZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein receptor-binding domain in complex with white-tailed deer ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IOS", "evidence_id": "EV-PDB-8IOS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8IOS", "doi": "10.1038/s41467-023-38435-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IOS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 XBB.1 spike glycoprotein (closed-1 state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IOU", "evidence_id": "EV-PDB-8IOU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "8IOU", "doi": "10.1038/s41467-023-38435-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1 spike glycoprotein in complex with ACE2 (1-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IOV", "evidence_id": "EV-PDB-8IOV-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "8IOV", "doi": "10.1038/s41467-023-38435-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1 spike RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IV4", "evidence_id": "EV-PDB-8IV4-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.59}, "provenance": {"deposit_id": "8IV4", "doi": "10.1093/procel/pwad040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IV4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 3E2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IV5", "evidence_id": "EV-PDB-8IV5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.77}, "provenance": {"deposit_id": "8IV5", "doi": "10.1093/procel/pwad040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IV5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "BA.4/5 variant spike protein (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IX3", "evidence_id": "EV-PDB-8IX3-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.98}, "provenance": {"deposit_id": "8IX3", "doi": "10.1128/jvi.01137-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IX3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J1Q", "evidence_id": "EV-PDB-8J1Q-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8J1Q", "doi": "10.3390/molecules28124645", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J1Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS CoV-2 RBD and Aptamer complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J1T", "evidence_id": "EV-PDB-8J1T-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8J1T", "doi": "10.1038/s41467-023-43798-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J1T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refined cryo-EM structure of Omicron BA.5 RBD in complex with 8-9D Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A,B,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J1V", "evidence_id": "EV-PDB-8J1V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "8J1V", "doi": "10.1038/s41467-023-43798-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J1V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV2 Omicron BA.5 spike in complex with 8-9D Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J26", "evidence_id": "EV-PDB-8J26-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8J26", "doi": "10.3390/molecules28124645", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J26"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of SARS CoV-2 RBD and Aptamer complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JAP", "evidence_id": "EV-PDB-8JAP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.81}, "provenance": {"deposit_id": "8JAP", "doi": "10.1038/s41467-024-54746-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JAP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 WT RBD in complex with W328-6H2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JIO", "evidence_id": "EV-PDB-8JIO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8JIO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JIO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB spike protein (S) in complex with monoclonal antibody 6I18"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JJE", "evidence_id": "EV-PDB-8JJE-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8JJE", "doi": "10.1126/scitranslmed.adi2623", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JJE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RBD of SARS-CoV2 spike protein with ACE2 decoy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JMM", "evidence_id": "EV-PDB-8JMM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "8JMM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JMM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of XBB spike protein (S) dimer-trimer in complex with bispecific antibody G7-Fc at 3.75 Angstroms resolution."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JVA", "evidence_id": "EV-PDB-8JVA-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "8JVA", "doi": "10.1038/s41392-024-01847-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JVA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the N-terminal domain of Omicron BA.1 in complex with nanobody N235 and S2L20 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYM", "evidence_id": "EV-PDB-8JYM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "8JYM", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 XBB.1.5 spike glycoprotein (closed state 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYN", "evidence_id": "EV-PDB-8JYN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8JYN", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (1-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYO", "evidence_id": "EV-PDB-8JYO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8JYO", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (2-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYP", "evidence_id": "EV-PDB-8JYP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "8JYP", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1.5 spike RBD in complex with ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K45", "evidence_id": "EV-PDB-8K45-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.66}, "provenance": {"deposit_id": "8K45", "doi": "10.1002/mco2.397", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K45"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses including all major Omicron strains"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYK", "evidence_id": "EV-PDB-8JYK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "8JYK", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 XBB.1.5 spike glycoprotein (closed state 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JIN", "evidence_id": "EV-PDB-8JIN-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "8JIN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JIN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The local refined map of XBB spike protein (S) in complex with bispecific antibody G7-Fc"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IVA", "evidence_id": "EV-PDB-8IVA-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "8IVA", "doi": "10.1093/procel/pwad040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IVA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs XMA01 and 3E2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IV8", "evidence_id": "EV-PDB-8IV8-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.92}, "provenance": {"deposit_id": "8IV8", "doi": "10.1093/procel/pwad040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IV8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 3E2 and 1C4 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ITU", "evidence_id": "EV-PDB-8ITU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.68}, "provenance": {"deposit_id": "8ITU", "doi": "10.1038/s42003-023-04759-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ITU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 IgG."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IOT", "evidence_id": "EV-PDB-8IOT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "8IOT", "doi": "10.1038/s41467-023-38435-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IOT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 XBB.1 spike glycoprotein (closed-2 state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IFY", "evidence_id": "EV-PDB-8IFY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "8IFY", "doi": "10.1128/jvi.00505-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IFY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein in complex with white-tailed deer ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IDN", "evidence_id": "EV-PDB-8IDN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "8IDN", "doi": "10.1107/S2059798323005041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IDN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of RBD/E77-Fab complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9H", "evidence_id": "EV-PDB-8I9H-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8I9H", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-RBD (Omicron XBB.1) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SIQ", "evidence_id": "EV-PDB-8SIQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8SIQ", "doi": "10.1016/j.celrep.2025.115948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SIQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibodies CC25.36 and CV38-142 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FUC", "GOL", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SGU", "evidence_id": "EV-PDB-8SGU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "8SGU", "doi": "10.1016/j.str.2023.11.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SGU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SDH", "evidence_id": "EV-PDB-8SDH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "8SDH", "doi": "10.1016/j.celrep.2025.115948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SDH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.56"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SDG", "evidence_id": "EV-PDB-8SDG-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "8SDG", "doi": "10.1016/j.celrep.2025.115948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SDG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.43"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPD", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SDF", "evidence_id": "EV-PDB-8SDF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.79}, "provenance": {"deposit_id": "8SDF", "doi": "10.1016/j.celrep.2025.115948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SDF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.4"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RRN", "evidence_id": "EV-PDB-8RRN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "8RRN", "doi": "10.1128/jvi.01223-24", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RRN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 S RBD in complex with pT1616 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ASN-TYR-ASN-TYR-LEU-PHE-ARG-LEU-PHE (chains C,F,I,L,O,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RJH", "evidence_id": "EV-PDB-8RJH-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8RJH", "doi": "10.1172/jci.insight.202235", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RJH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HLA A*2402-NF9_6F pMHC complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RJ5", "evidence_id": "EV-PDB-8RJ5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "8RJ5", "doi": "10.1172/jci.insight.202235", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RJ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "P1-15 T-cell Receptor bound to HLA A*2402-NF9 pMHC complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "MG", "NA", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains G,H,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RHQ", "evidence_id": "EV-PDB-8RHQ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "8RHQ", "doi": "10.1016/j.crstbi.2024.100148", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RHQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HLA-A*11:01 in complex with SVLNDIFSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains G,H,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RH6", "evidence_id": "EV-PDB-8RH6-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "8RH6", "doi": "10.1016/j.crstbi.2024.100148", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RH6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HLA-A*11:01 in complex with SVLNDILSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NA", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8REF", "evidence_id": "EV-PDB-8REF-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8REF", "doi": "10.1016/j.crstbi.2024.100148", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8REF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HLA B*13:01 in complex with SVLNDILARL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RCV", "evidence_id": "EV-PDB-8RCV-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "8RCV", "doi": "10.1016/j.crstbi.2024.100148", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RCV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HLA B*13:01 in complex with SVLNDIFSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPO", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RBY", "evidence_id": "EV-PDB-8RBY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "8RBY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of the SARS-CoV-2 receptor binding domain in complex with the neutralizing nanobody 1.26"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "CD", "EDO", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SARS-CoV-2 Spike-derived peptide S976-984 S982A mutant (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RBV", "evidence_id": "EV-PDB-8RBV-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "8RBV", "doi": "10.1016/j.crstbi.2024.100148", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Spike-derived peptide S976-984 S982A mutant (VLNDILARL) presented by HLA-A*02:01"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA", "PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RBU", "evidence_id": "EV-PDB-8RBU-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8RBU", "doi": "10.1016/j.crstbi.2024.100148", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of HLA-A*11:01 in complex with SVLNDILARL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8R8K", "evidence_id": "EV-PDB-8R8K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "8R8K", "doi": "10.1016/j.xcrm.2024.101553", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8R8K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB-4 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8R87", "evidence_id": "EV-PDB-8R87-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8R87", "doi": "10.1038/s41541-025-01113-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8R87"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Sars-Cov2 S trimer without RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8R80", "evidence_id": "EV-PDB-8R80-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.03}, "provenance": {"deposit_id": "8R80", "doi": "10.1016/j.xcrm.2024.101553", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8R80"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Delta RBD in complex with XBB-9 Fab and an anti-Fab nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8R1D", "evidence_id": "EV-PDB-8R1D-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.37}, "provenance": {"deposit_id": "8R1D", "doi": "10.1038/s41467-024-46982-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8R1D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SD1-3 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8R1C", "evidence_id": "EV-PDB-8R1C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8R1C", "doi": "10.1038/s41467-024-46982-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8R1C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SD1-2 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QZR", "evidence_id": "EV-PDB-8QZR-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.77}, "provenance": {"deposit_id": "8QZR", "doi": "10.1038/s41467-024-47393-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QZR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 delta RBD complexed with BA.4/5-9 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QTD", "evidence_id": "EV-PDB-8QTD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8QTD", "doi": "10.1016/j.xcrm.2024.101553", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 BA.2.86 Spike and XBB-7 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QSQ", "evidence_id": "EV-PDB-8QSQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8QSQ", "doi": "10.1016/j.xcrm.2024.101553", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QSQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Locally refined SARS-CoV-2 BA-2.86 Spike receptor binding domain (RBD) complexed with angiotensin converting enzyme 2 (ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QRG", "evidence_id": "EV-PDB-8QRG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8QRG", "doi": "10.1016/j.xcrm.2024.101553", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QRG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 delta RBD complexed with XBB-2 Fab and NbC1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QRF", "evidence_id": "EV-PDB-8QRF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8QRF", "doi": "10.1016/j.xcrm.2024.101553", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QRF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 delta RBD complexed with XBB-6 and beta-49 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QQ0", "evidence_id": "EV-PDB-8QQ0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8QQ0", "doi": "10.1016/j.ebiom.2023.104960", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QQ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein bound to neutralising antibody UZGENT_A3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QPR", "evidence_id": "EV-PDB-8QPR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8QPR", "doi": "10.1016/j.ebiom.2023.104960", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein bound to human neutralising antibody UZGENT_G5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "PRO", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QH0", "evidence_id": "EV-PDB-8QH0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.87}, "provenance": {"deposit_id": "8QH0", "doi": "10.1016/j.isci.2024.110354", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QH0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD with the antibody Cv2.3194"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q95", "evidence_id": "EV-PDB-8Q95-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "8Q95", "doi": "10.1016/j.antiviral.2023.105778", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q95"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 BA.1 RBD with neutralizing-VHHs Ma16B06 and Ma3F05"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q94", "evidence_id": "EV-PDB-8Q94-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8Q94", "doi": "10.1016/j.antiviral.2023.105778", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q94"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of The SARS-COV-2 BA.2.75 RBD with neutralizing-VHHs Re32D03 and Ma3B12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q93", "evidence_id": "EV-PDB-8Q93-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8Q93", "doi": "10.1016/j.antiviral.2023.105778", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q93"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-COV-2 RBD with neutralizing-VHHs Re30H02 and Re21D01"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q5Y", "evidence_id": "EV-PDB-8Q5Y-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8Q5Y", "doi": "10.1038/s41467-024-50286-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q5Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryoEM structure of SARS-CoV2 Spike trimer in complex with Fab23"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PSD", "evidence_id": "EV-PDB-8PSD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8PSD", "doi": "10.1016/j.jinf.2023.10.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PSD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 XBB 1.0 closed conformation."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PQ2", "evidence_id": "EV-PDB-8PQ2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "8PQ2", "doi": "10.1016/j.jinf.2023.10.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PQ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB 1.0 RBD bound to P4J15 (Local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "NAG", "XIO", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1,Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P9Y", "evidence_id": "EV-PDB-8P9Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "8P9Y", "doi": "10.1021/acs.jmedchem.3c00576", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P9Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein S:D614G mutant in 3-down with binding site of an entry inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1,Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P99", "evidence_id": "EV-PDB-8P99-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8P99", "doi": "10.1021/acs.jmedchem.3c00576", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P99"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S-protein:D614G mutant in 1-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P5M", "evidence_id": "EV-PDB-8P5M-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8P5M", "doi": "10.1038/s41467-024-50286-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P5M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike RBD in complex with Mab-23 (Fab)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OYU", "evidence_id": "EV-PDB-8OYU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "8OYU", "doi": "10.1098/rsob.230252", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OYU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OYT", "evidence_id": "EV-PDB-8OYT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8OYT", "doi": "10.1098/rsob.230252", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OYT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains EEE)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8OWV", "evidence_id": "EV-PDB-8OWV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.73}, "provenance": {"deposit_id": "8OWV", "doi": "10.1098/rsob.230252", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8OWV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "H6 and F2 nanobodies bound to SARS-CoV-2 spike RBD"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8KHD", "evidence_id": "EV-PDB-8KHD-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8KHD", "doi": "10.1016/j.celrep.2023.113653", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8KHD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The interface structure of Omicron RBD binding to 5817 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8KER", "evidence_id": "EV-PDB-8KER-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "8KER", "doi": "10.1038/s41421-024-00648-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8KER"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB Variant Spike protein complexed with broadly neutralizing antibody PW5-535"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SIT", "evidence_id": "EV-PDB-8SIT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "8SIT", "doi": "10.1016/j.celrep.2025.115948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SIT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.24 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SMI", "evidence_id": "EV-PDB-8SMI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8SMI", "doi": "10.1016/j.str.2023.11.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SMI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of antibody WRAIR-2123 in complex with SARS-CoV-2 receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,E,G,K)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SMT", "evidence_id": "EV-PDB-8SMT-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "8SMT", "doi": "10.1016/j.str.2023.11.015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SMT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of antibody WRAIR-2134 in complex with SARS-CoV-2 receptor binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SUO", "evidence_id": "EV-PDB-8SUO-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8SUO", "doi": "10.1126/scitranslmed.ado2817", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SUO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BA.2/AZD1061/AZD3152 structure analysis"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SWH", "evidence_id": "EV-PDB-8SWH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88}, "provenance": {"deposit_id": "8SWH", "doi": "10.1016/j.celrep.2024.114307", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 (HP-GSAS-Mut7) spike NTD in complex with TXG-0078 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T20", "evidence_id": "EV-PDB-8T20-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "8T20", "doi": "10.1002/jmv.29163", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T20"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of mink variant Y453F trimeric spike protein bound to two mink ACE2 receptors"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T22", "evidence_id": "EV-PDB-8T22-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.83}, "provenance": {"deposit_id": "8T22", "doi": "10.1002/jmv.29163", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T22"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors at downRBD conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1,Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8THF", "evidence_id": "EV-PDB-8THF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "8THF", "doi": "10.1038/s41541-024-00922-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8THF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 S-6P-no-RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TM1", "evidence_id": "EV-PDB-8TM1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "8TM1", "doi": "10.1038/s42003-023-05649-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TM1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Antibody N3-1 bound to RBDs in the up and down conformations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TYL", "evidence_id": "EV-PDB-8TYL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "8TYL", "doi": "10.1038/s41598-024-52499-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TYL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural and biochemical rationale for Beta variant protein booster vaccine broad cross-neutralization of SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TYO", "evidence_id": "EV-PDB-8TYO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "8TYO", "doi": "10.1038/s41598-024-52499-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structural and biochemical rationale for Beta variant protein booster vaccine broad cross-neutralization of SARS-CoV-2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UG9", "evidence_id": "EV-PDB-8UG9-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "8UG9", "doi": "10.1371/journal.ppat.1012493", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UG9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 spike/Nb5 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKD", "evidence_id": "EV-PDB-8UKD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8UKD", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer consensus (S-GSAS-Omicron-XBB.1.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8USZ", "evidence_id": "EV-PDB-8USZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "8USZ", "doi": "10.1038/s41541-024-01013-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8USZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Full-Length Spike Protein of Omicron XBB.1.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UUL", "evidence_id": "EV-PDB-8UUL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8UUL", "doi": "10.7554/eLife.74060", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UUL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prototypic SARS-CoV-2 spike (containing K417) in the closed conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MAN", "NAG", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UUM", "evidence_id": "EV-PDB-8UUM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8UUM", "doi": "10.7554/eLife.74060", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UUM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prototypic SARS-CoV-2 spike (containing K417) in the open conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UUN", "evidence_id": "EV-PDB-8UUN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8UUN", "doi": "10.7554/eLife.74060", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UUN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prototypic SARS-CoV-2 spike (containing V417) in the closed conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0L", "evidence_id": "EV-PDB-8V0L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8V0L", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD-down Spike Protein Trimer 1 (S-RRAR-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0M", "evidence_id": "EV-PDB-8V0M-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8V0M", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD-down Spike Protein Trimer 2 (S-RRAR-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0N", "evidence_id": "EV-PDB-8V0N-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8V0N", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD-down Spike Protein Trimer 3 (S-RRAR-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0O", "evidence_id": "EV-PDB-8V0O-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8V0O", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0P", "evidence_id": "EV-PDB-8V0P-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8V0P", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0Q", "evidence_id": "EV-PDB-8V0Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8V0Q", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD down Spike Protein Trimer 3 (S-GSAS-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0R", "evidence_id": "EV-PDB-8V0R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8V0R", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-XBB.1.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0S", "evidence_id": "EV-PDB-8V0S-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8V0S", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-XBB.1.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0T", "evidence_id": "EV-PDB-8V0T-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8V0T", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer 3 (S-GSAS-Omicron-XBB.1.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0U", "evidence_id": "EV-PDB-8V0U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8V0U", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer 4 (S-GSAS-Omicron-XBB.1.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0W", "evidence_id": "EV-PDB-8V0W-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8V0W", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-EG.5 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-EG.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0X", "evidence_id": "EV-PDB-8V0X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8V0X", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-EG.5 3-RBD down Spike Protein Trimer 3 (S-GSAS-Omicron-EG.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V4F", "evidence_id": "EV-PDB-8V4F-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "8V4F", "doi": "10.1016/j.xcrm.2024.101577", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V4F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Model and map from local refinement of a CAB-A17 - Omicron Ba.1 spike complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2,Fibritin (chains E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V5V", "evidence_id": "EV-PDB-8V5V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.93}, "provenance": {"deposit_id": "8V5V", "doi": "10.1016/j.celrep.2025.116052", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V5V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VCR", "evidence_id": "EV-PDB-8VCR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8VCR", "doi": "10.1016/j.str.2024.08.022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VCR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike S2 bound to Fab 54043-5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VIA", "evidence_id": "EV-PDB-8VIA-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8VIA", "doi": "10.1016/j.celrep.2024.114922", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VIA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Protective effect of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VIA", "evidence_id": "EV-PDB-8VIA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8VIA", "doi": "10.1016/j.celrep.2024.114922", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VIA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Protective effect of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VIF", "evidence_id": "EV-PDB-8VIF-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8VIF", "doi": "10.1016/j.xcrm.2024.101668", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VIF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike omicron (BA.1) ectodomain trimer in complex with SC27 Fab, local refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VAO", "evidence_id": "EV-PDB-8VAO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8VAO", "doi": "10.1038/s41467-024-50976-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VAO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Simulation-driven design of prefusion stabilized SARS-CoV-2 spike S2 antigen"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V0V", "evidence_id": "EV-PDB-8V0V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8V0V", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V0V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-EG.5 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-EG.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MAN", "NAG", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UUO", "evidence_id": "EV-PDB-8UUO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8UUO", "doi": "10.7554/eLife.74060", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UUO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prototypic SARS-CoV-2 spike (containing V417) in the open conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UKF", "evidence_id": "EV-PDB-8UKF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8UKF", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UKF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-EG.5 3-RBD down Spike Protein Trimer consensus (S-GSAS-Omicron-EG.5)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UK1", "evidence_id": "EV-PDB-8UK1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8UK1", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UK1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD-down Spike Protein Trimer consensus (S-RRAR-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UIR", "evidence_id": "EV-PDB-8UIR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8UIR", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UIR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-XBB.1.16 3-RBD down Spike Protein Trimer consensus (S-GSAS-Omicron-XBB.1.16)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8U1G", "evidence_id": "EV-PDB-8U1G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8U1G", "doi": "10.1038/s41467-024-45404-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8U1G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Prefusion-stabilized SARS-CoV-2 S2 subunit"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FLC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Stem helix peptide of Spike protein S2' (chains M,N,S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TMY", "evidence_id": "EV-PDB-8TMY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "8TMY", "doi": "10.1016/j.celrep.2026.117439", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CHM-16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TMA", "evidence_id": "EV-PDB-8TMA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8TMA", "doi": "10.1038/s42003-023-05649-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TMA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Antibody N3-1 bound to RBD in the up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TAZ", "evidence_id": "EV-PDB-8TAZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "8TAZ", "doi": "10.1002/jmv.29163", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TAZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T25", "evidence_id": "EV-PDB-8T25-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.62}, "provenance": {"deposit_id": "8T25", "doi": "10.1002/jmv.29163", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the RBD-ACE2 interface of the SARS-CoV-2 trimeric spike protein bound to ACE2 receptor after local refinement at downRBD conformation."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T23", "evidence_id": "EV-PDB-8T23-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.87}, "provenance": {"deposit_id": "8T23", "doi": "10.1002/jmv.29163", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T23"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the RBD-ACE2 interface of the SARS-CoV-2 trimeric spike protein bound to ACE2 receptor after local refinement at upRBD conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SIS", "evidence_id": "EV-PDB-8SIS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "8SIS", "doi": "10.1016/j.celrep.2025.115948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SIS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC84.2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SIR", "evidence_id": "EV-PDB-8SIR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8SIR", "doi": "10.1016/j.celrep.2025.115948", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SIR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with broadly neutralizing antibody CC25.54 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKE", "evidence_id": "EV-PDB-8VKE-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8VKE", "doi": "10.1016/j.xcrm.2024.101668", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike omicron (BA.1) RBD ectodomain dimer-of-trimers in complex with SC27 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKM", "evidence_id": "EV-PDB-8VKM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "8VKM", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKN", "evidence_id": "EV-PDB-8VKN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.93}, "provenance": {"deposit_id": "8VKN", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (focused refinement of RBD and mouse ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKO", "evidence_id": "EV-PDB-8VKO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "8VKO", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKP", "evidence_id": "EV-PDB-8VKP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8VKP", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VQ9", "evidence_id": "EV-PDB-8VQ9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8VQ9", "doi": "10.1038/s41467-024-49656-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VQ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prefusion stabilized structure of the SARS-CoV-2 fusion machinery"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VQB", "evidence_id": "EV-PDB-8VQB-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8VQB", "doi": "10.1038/s41467-024-49656-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VQB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prefusion stabilized structure of the SARS-CoV-2 fusion machinery"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VQR", "evidence_id": "EV-PDB-8VQR-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.565}, "provenance": {"deposit_id": "8VQR", "doi": "10.1371/journal.ppat.1012204", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VQR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric SARS-CoV-2 RBD complexed with chimeric raccoon dog ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SARS-CoV-2 Omicron variant spike glycoprotein C-terminal heptad repeat domain (chains D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VYA", "evidence_id": "EV-PDB-8VYA-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.12}, "provenance": {"deposit_id": "8VYA", "doi": "10.1021/acschembio.5c00208", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VYA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron Variant Spike Glycoprotein Fusion Core (Q954H)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SARS-CoV-2 Omicron variant spike glycoprotein N-terminal heptad repeat domain (Q954H) (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VYA", "evidence_id": "EV-PDB-8VYA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.12}, "provenance": {"deposit_id": "8VYA", "doi": "10.1021/acschembio.5c00208", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VYA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron Variant Spike Glycoprotein Fusion Core (Q954H)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E,K,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VYE", "evidence_id": "EV-PDB-8VYE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8VYE", "doi": "10.1038/s41467-024-46536-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VYE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S (C.37 Lambda variant) plus S309, S2L20, and S2X303 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VYG", "evidence_id": "EV-PDB-8VYG-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8VYG", "doi": "10.1038/s41467-024-46536-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VYG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S RBD (C.37 Lambda variant) plus S309 Fab, local refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8W4F", "evidence_id": "EV-PDB-8W4F-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "8W4F", "doi": "10.1016/j.ijbiomac.2023.128191", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8W4F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike protein in complex with a trivalent nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDR", "evidence_id": "EV-PDB-8WDR-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "8WDR", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of BQ.1.1 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDS", "evidence_id": "EV-PDB-8WDS-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8WDS", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of BF.7 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDY", "evidence_id": "EV-PDB-8WDY-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "8WDY", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BQ.1.1 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WE0", "evidence_id": "EV-PDB-8WE0-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8WE0", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WE0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron XBB RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WE1", "evidence_id": "EV-PDB-8WE1-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.47}, "provenance": {"deposit_id": "8WE1", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WE1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BF.7 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WE4", "evidence_id": "EV-PDB-8WE4-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "8WE4", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WE4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WFH", "evidence_id": "EV-PDB-8WFH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "8WFH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WFH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Omicron BA.4/5 in complex with a neutralizing antibody scFv D1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike protein S1 (chains B,D,F,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WFM", "evidence_id": "EV-PDB-8WFM-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "8WFM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WFM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Omicron BA.1 in complex with a neutralizing antibody scFv T11"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WGV", "evidence_id": "EV-PDB-8WGV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "8WGV", "doi": "10.1038/s41590-024-01776-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WGV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2(S375) Spike (S6P)/hACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WGW", "evidence_id": "EV-PDB-8WGW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8WGW", "doi": "10.1038/s41590-024-01776-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of RBD-ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHU", "evidence_id": "EV-PDB-8WHU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8WHU", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike Trimer of BA.2.86 in complex with two hACE2s"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHV", "evidence_id": "EV-PDB-8WHV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "8WHV", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike Trimer of BA.2.86 with three RBDs down"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WOX", "evidence_id": "EV-PDB-8WOX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "8WOX", "doi": "10.1128/mbio.02988-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WOX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 prototype RBD in complex with rabbit ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WOY", "evidence_id": "EV-PDB-8WOY-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "8WOY", "doi": "10.1128/mbio.02988-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WOY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with rabbit ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WPW", "evidence_id": "EV-PDB-8WPW-7", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.49}, "provenance": {"deposit_id": "8WPW", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WPW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WPY", "evidence_id": "EV-PDB-8WPY-7", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "8WPY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WPY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRH", "evidence_id": "EV-PDB-8WRH-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "8WRH", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 XBB.1.5.70 in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRL", "evidence_id": "EV-PDB-8WRL-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "8WRL", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Spike glycoprotein,Spike glycoprotein,Fusion protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRO", "evidence_id": "EV-PDB-8WRO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8WRO", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5.10 spike protein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WTD", "evidence_id": "EV-PDB-8WTD-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "8WTD", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5.10 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WTJ", "evidence_id": "EV-PDB-8WTJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.64}, "provenance": {"deposit_id": "8WTJ", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5.70 spike protein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WXL", "evidence_id": "EV-PDB-8WXL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "8WXL", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WXL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 BA.2.86 spike glycoprotein (closed state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WYH", "evidence_id": "EV-PDB-8WYH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8WYH", "doi": "10.1038/s41467-024-51973-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The global map of Omicron Subvariants Spike with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WYJ", "evidence_id": "EV-PDB-8WYJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8WYJ", "doi": "10.1038/s41467-024-51973-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The global map of Omicron Subvariants Spike with two antibodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRM", "evidence_id": "EV-PDB-8WRM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.34}, "provenance": {"deposit_id": "8WRM", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 spike protein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WP8", "evidence_id": "EV-PDB-8WP8-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "8WP8", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WMF", "evidence_id": "EV-PDB-8WMF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "8WMF", "doi": "10.1111/1348-0421.13165", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WMF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein (closed-1 state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WMD", "evidence_id": "EV-PDB-8WMD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "8WMD", "doi": "10.1111/1348-0421.13165", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WMD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein (closed-2 state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WLR", "evidence_id": "EV-PDB-8WLR-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "8WLR", "doi": "10.1128/jvi.00451-24", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WLR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 prototype spike protein receptor-binding domain in complex with hippopotamus ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WLO", "evidence_id": "EV-PDB-8WLO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.62}, "provenance": {"deposit_id": "8WLO", "doi": "10.1128/jvi.00451-24", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WLO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with hippopotamus ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHZ", "evidence_id": "EV-PDB-8WHZ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.93}, "provenance": {"deposit_id": "8WHZ", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 RBD in complex with hACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHW", "evidence_id": "EV-PDB-8WHW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "8WHW", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike Trimer of BA.2.86 with single RBD up"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHS", "evidence_id": "EV-PDB-8WHS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "8WHS", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike Trimer of BA.2.86 in complex with one hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDZ", "evidence_id": "EV-PDB-8WDZ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "8WDZ", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BQ.1 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VYF", "evidence_id": "EV-PDB-8VYF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8VYF", "doi": "10.1038/s41467-024-46536-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VYF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S NTD (C.37 Lambda variant) plus S2L20 and S2X303 Fabs, local refinement"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VQA", "evidence_id": "EV-PDB-8VQA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8VQA", "doi": "10.1038/s41467-024-49656-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VQA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Prefusion stabilized structure of the SARS-CoV-2 fusion machinery"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKL", "evidence_id": "EV-PDB-8VKL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "8VKL", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKK", "evidence_id": "EV-PDB-8VKK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "8VKK", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WZI", "evidence_id": "EV-PDB-8WZI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8WZI", "doi": "10.1107/S2059798324005229", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "One RBD up state of Spike glycoprotein, SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X55", "evidence_id": "EV-PDB-8X55-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "8X55", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X55"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike Trimer with T356K mutation (3 RBD down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X56", "evidence_id": "EV-PDB-8X56-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.93}, "provenance": {"deposit_id": "8X56", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X56"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike Trimer with T356K mutation (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X5R", "evidence_id": "EV-PDB-8X5R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "8X5R", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X5R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 Spike with K356T mutation (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XAL", "evidence_id": "EV-PDB-8XAL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8XAL", "doi": "10.1172/jci.insight.179726", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XAL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XBF", "evidence_id": "EV-PDB-8XBF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8XBF", "doi": "10.1172/jci.insight.179726", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XBF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with antibody O5C2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XE9", "evidence_id": "EV-PDB-8XE9-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8XE9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XE9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 RBD in complex with BD55-1205"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XG2", "evidence_id": "EV-PDB-8XG2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "8XG2", "doi": "10.4049/immunohorizons.2400026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XG2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of HLA-A/Pep14"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XI6", "evidence_id": "EV-PDB-8XI6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8XI6", "doi": "10.1128/jvi.00416-24", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XI6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BQ.1.1 Variant Spike Protein Complexed with MO11 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XK2", "evidence_id": "EV-PDB-8XK2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8XK2", "doi": "10.1038/s41419-024-06802-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XK2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A neutralizing nanobody VHH60 against wt SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XKC", "evidence_id": "EV-PDB-8XKC-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.18}, "provenance": {"deposit_id": "8XKC", "doi": "10.4049/immunohorizons.2400026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XKC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of HLA-A/Pep16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GLU-VAL-ASP-ASN-ALA-THR-ARG-PHE-ALA-SER-VAL-TYR (chains M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XKE", "evidence_id": "EV-PDB-8XKE-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.92}, "provenance": {"deposit_id": "8XKE", "doi": "10.4049/immunohorizons.2400026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XKE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of HLA-A/14-3-D"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XKI", "evidence_id": "EV-PDB-8XKI-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8XKI", "doi": "10.1038/s41419-024-06802-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XKI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "A neutralizing nanobody VHH60 against wt SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XLM", "evidence_id": "EV-PDB-8XLM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "8XLM", "doi": "10.1111/1348-0421.13165", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XLM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein in complex with ACE2 (1-up state)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XLV", "evidence_id": "EV-PDB-8XLV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "8XLV", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XLV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XMG", "evidence_id": "EV-PDB-8XMG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8XMG", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XMG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P), RBD-closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XMT", "evidence_id": "EV-PDB-8XMT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.31}, "provenance": {"deposit_id": "8XMT", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XMT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P), RBD-closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XN2", "evidence_id": "EV-PDB-8XN2-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "8XN2", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XN5", "evidence_id": "EV-PDB-8XN5-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.87}, "provenance": {"deposit_id": "8XN5", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XRQ", "evidence_id": "EV-PDB-8XRQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.19}, "provenance": {"deposit_id": "8XRQ", "doi": "10.1093/jimmun/vkae056", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XRQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.1 spike RBD in complex bound with VacBB-639"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSD", "evidence_id": "EV-PDB-8XSD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "8XSD", "doi": "10.1038/s41392-024-02114-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.5 Spike complex with CR9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSE", "evidence_id": "EV-PDB-8XSE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8XSE", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSF", "evidence_id": "EV-PDB-8XSF-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.16}, "provenance": {"deposit_id": "8XSF", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD + IMCAS-364 + hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSI", "evidence_id": "EV-PDB-8XSI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "8XSI", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD + IMCAS-364 (Local Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSJ", "evidence_id": "EV-PDB-8XSJ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "8XSJ", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSL", "evidence_id": "EV-PDB-8XSL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8XSL", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike + IMCAS-123"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IDU", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUR", "evidence_id": "EV-PDB-8XUR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "8XUR", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike Trimer in complex with heparan sulfate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IDU", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUS", "evidence_id": "EV-PDB-8XUS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "8XUS", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "JN.1 Spike Trimer in complex with heparan sulfate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IDU", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUT", "evidence_id": "EV-PDB-8XUT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8XUT", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 Spike Trimer in complex with heparan sulfate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUX", "evidence_id": "EV-PDB-8XUX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "8XUX", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 BA.2.86 spike protein (1-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUY", "evidence_id": "EV-PDB-8XUY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "8XUY", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUZ", "evidence_id": "EV-PDB-8XUZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "8XUZ", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up and 1-down state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XV0", "evidence_id": "EV-PDB-8XV0-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8XV0", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XV0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XV1", "evidence_id": "EV-PDB-8XV1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "8XV1", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XV1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (down state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XVM", "evidence_id": "EV-PDB-8XVM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8XVM", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XVM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (3-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XXW", "evidence_id": "EV-PDB-8XXW-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "8XXW", "doi": "10.1016/j.celrep.2024.114235", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XXW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Fab M2-7 complexed with SARS-Cov2 RBD and human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IDU", "NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUU", "evidence_id": "EV-PDB-8XUU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.69}, "provenance": {"deposit_id": "8XUU", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86-T356K Spike Trimer in complex with heparan sulfate (Local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XNK", "evidence_id": "EV-PDB-8XNK-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "8XNK", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XNK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XN3", "evidence_id": "EV-PDB-8XN3-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.64}, "provenance": {"deposit_id": "8XN3", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XN3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XM5", "evidence_id": "EV-PDB-8XM5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "8XM5", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XM5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XEF", "evidence_id": "EV-PDB-8XEF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.41}, "provenance": {"deposit_id": "8XEF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XEF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cocktail GC2050-GC2225"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XEA", "evidence_id": "EV-PDB-8XEA-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "8XEA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 spike protein in complex with BD55-1205"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X5Q", "evidence_id": "EV-PDB-8X5Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "8X5Q", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X5Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 Spike with K356T mutation (3 RBD down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X50", "evidence_id": "EV-PDB-8X50-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.82}, "provenance": {"deposit_id": "8X50", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X50"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike Trimer with ins483V mutation (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X4Z", "evidence_id": "EV-PDB-8X4Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "8X4Z", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X4Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike Trimer with ins483V mutation (3 RBD down)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X4H", "evidence_id": "EV-PDB-8X4H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65}, "provenance": {"deposit_id": "8X4H", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X4H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 JN.1 Spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "PO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X0Y", "evidence_id": "EV-PDB-8X0Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "8X0Y", "doi": "10.1371/journal.ppat.1012246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of JM-1A in complex with SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X0X", "evidence_id": "EV-PDB-8X0X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "8X0X", "doi": "10.1371/journal.ppat.1012246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of JE-5C in complex with SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XZ9", "evidence_id": "EV-PDB-8XZ9-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.37}, "provenance": {"deposit_id": "8XZ9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XZ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike in complex with bovine ACE2 (bound 2 ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YZ6", "evidence_id": "EV-PDB-8YZ6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.55}, "provenance": {"deposit_id": "8YZ6", "doi": "10.1371/journal.ppat.1012246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YZ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (BA.1) in complex with Fab of JH-8B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YZ5", "evidence_id": "EV-PDB-8YZ5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.93}, "provenance": {"deposit_id": "8YZ5", "doi": "10.1371/journal.ppat.1012246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YZ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta Spike in complex with Fab of JE-5C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YWX", "evidence_id": "EV-PDB-8YWX-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8YWX", "doi": "10.1080/22221751.2024.2373307", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YWX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "the complex structure of the H4B6 Fab with the RBD of Omicron BA.5 S protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YWW", "evidence_id": "EV-PDB-8YWW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8YWW", "doi": "10.1080/22221751.2024.2373307", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YWW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of HKU1-B S protein with bsAb1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YWE", "evidence_id": "EV-PDB-8YWE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "8YWE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YWE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 Omicron BA.2.86 S complexed with Abs G7-Fc"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YUC", "evidence_id": "EV-PDB-8YUC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.51}, "provenance": {"deposit_id": "8YUC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YUC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 ConSp RBD in complex with antibodies PDI222 Fab and COVA1-16 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YUB", "evidence_id": "EV-PDB-8YUB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.49}, "provenance": {"deposit_id": "8YUB", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YUB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 ConSp RBD in complex with neutralizing antibody CC25.4 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YRP", "evidence_id": "EV-PDB-8YRP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.64}, "provenance": {"deposit_id": "8YRP", "doi": "10.1371/journal.ppat.1012246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YRP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta Spike in complex with JM-1A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,D,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YRO", "evidence_id": "EV-PDB-8YRO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "8YRO", "doi": "10.1371/journal.ppat.1012246", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YRO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta Spike in complex with JL-8C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YKH", "evidence_id": "EV-PDB-8YKH-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "8YKH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YKH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike RBD in complex with NT-108 scFv"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YKG", "evidence_id": "EV-PDB-8YKG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.28}, "provenance": {"deposit_id": "8YKG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YKG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike glycoprotein in complex with NT-108 scFv (1-up state)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YBZ", "evidence_id": "EV-PDB-8YBZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8}, "provenance": {"deposit_id": "8YBZ", "doi": "10.1039/d5ra00373c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YBZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State - II: Spike 3-up RBD with THSC20.HVTR26 (Fab26)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YBY", "evidence_id": "EV-PDB-8YBY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "8YBY", "doi": "10.1039/d5ra00373c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State - I: Spike 2-up RBD with THSC20.HVTR26 (Fab26) - single Fab masked"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YBS", "evidence_id": "EV-PDB-8YBS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.54}, "provenance": {"deposit_id": "8YBS", "doi": "10.1039/d5ra00373c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YBS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State - I: Spike 2-up RBD with THSC20.HVTR04 (Fab4)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y5J", "evidence_id": "EV-PDB-8Y5J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.94}, "provenance": {"deposit_id": "8Y5J", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y5J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y4C", "evidence_id": "EV-PDB-8Y4C-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "8Y4C", "doi": "10.1038/s41392-024-01940-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y4C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 S-trimer in complex with Nab XGv280"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(8-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y4A", "evidence_id": "EV-PDB-8Y4A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8Y4A", "doi": "10.1038/s41392-024-01940-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y4A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 S-trimer in complex with Nab XG2v046"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 RBD (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y32", "evidence_id": "EV-PDB-8Y32-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.13}, "provenance": {"deposit_id": "8Y32", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y32"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86-V483 RBD in complex with bACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y18", "evidence_id": "EV-PDB-8Y18-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8Y18", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y18"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1 RBD in complex with human ACE2 (local refinement from the spike protein)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y16", "evidence_id": "EV-PDB-8Y16-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "8Y16", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y16"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y0Y", "evidence_id": "EV-PDB-8Y0Y-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "8Y0Y", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the 123-316 scDb/PT-RBD complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XZD", "evidence_id": "EV-PDB-8XZD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "8XZD", "doi": "10.1016/j.virs.2024.06.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XZD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of fox ACE2 and Omicron BF.7 RBD complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XZA", "evidence_id": "EV-PDB-8XZA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.07}, "provenance": {"deposit_id": "8XZA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XZA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike in complex with bovine ACE2 (Local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XZ8", "evidence_id": "EV-PDB-8XZ8-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65}, "provenance": {"deposit_id": "8XZ8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XZ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 Spike in complex with bovine ACE2 (bound 1 ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XZ5", "evidence_id": "EV-PDB-8XZ5-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "8XZ5", "doi": "10.1073/pnas.2504517123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XZ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 S and moesin complex structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XZ4", "evidence_id": "EV-PDB-8XZ4-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.129}, "provenance": {"deposit_id": "8XZ4", "doi": "10.1073/pnas.2504517123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XZ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 S and radixin complex structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XZ0", "evidence_id": "EV-PDB-8XZ0-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.035}, "provenance": {"deposit_id": "8XZ0", "doi": "10.1073/pnas.2504517123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XZ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal complex structure of SARS-CoV-2 S bound to human ezrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Signal peptide, Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XYZ", "evidence_id": "EV-PDB-8XYZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "8XYZ", "doi": "10.1016/j.virs.2024.06.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XYZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of fox ACE2 and PT RBD complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XYO", "evidence_id": "EV-PDB-8XYO-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8XYO", "doi": "10.1128/jvi.00283-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CX1 receptor binding domain in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XYM", "evidence_id": "EV-PDB-8XYM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74}, "provenance": {"deposit_id": "8XYM", "doi": "10.1128/jvi.00283-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XYM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CX1 spike protein (6P)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "ASN-TYR-ASN-TYR-GLN-TYR-ARG-LEU-PHE (chains F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z08", "evidence_id": "EV-PDB-8Z08-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.01}, "provenance": {"deposit_id": "8Z08", "doi": "10.1038/s41590-024-02051-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z08"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structure of HLA-A*2402 complex with peptide from SARS-CoV-2 S448-456 NYNYQYRLF(BA.2.12.1)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z3W", "evidence_id": "EV-PDB-8Z3W-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "8Z3W", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z3W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G S with one ACE2 receptor binding (RB1) in prefusion conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z4X", "evidence_id": "EV-PDB-8Z4X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8Z4X", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z4X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G S with two ACE2 receptors binding (RB2) in prefusion conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z64", "evidence_id": "EV-PDB-8Z64-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "8Z64", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z64"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G S with three ACE2 receptors binding (RB3) in prefusion conformation (focused refinement of NTD-SD1-RBD-ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6A", "evidence_id": "EV-PDB-8Z6A-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "8Z6A", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G S with three ACE2 receptors binding (RB3) in prefusion conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6Q", "evidence_id": "EV-PDB-8Z6Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.41}, "provenance": {"deposit_id": "8Z6Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 XBB.1.16 Spike in complex with CYFN1006-1(S-CYFN1006-1 dimer trimer)."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Spike glycoprotein,Fibritin,Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6R", "evidence_id": "EV-PDB-8Z6R-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.87}, "provenance": {"deposit_id": "8Z6R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of XBB.1.16 S trimer with 3 down-RBDs complex with antibody CYFN1006-1."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6S", "evidence_id": "EV-PDB-8Z6S-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "8Z6S", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of XBB.1.16 S trimer with 2 down-RBDs complex with antibody CYFN1006-1."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6U", "evidence_id": "EV-PDB-8Z6U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.83}, "provenance": {"deposit_id": "8Z6U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 EG.5.1 Spike in complex with CYFN1006-2(S-CYFN1006-2 dimer trimer)."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6W", "evidence_id": "EV-PDB-8Z6W-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8Z6W", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of EG.5.1 S trimer with 3 down-RBDs complex with antibody CYFN1006-2."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6X", "evidence_id": "EV-PDB-8Z6X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "8Z6X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of EG.5.1 RBD in complex with antibody CYFN1006-2."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z7B", "evidence_id": "EV-PDB-8Z7B-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8Z7B", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z7B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of NTD-SD1-RBD-ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z7G", "evidence_id": "EV-PDB-8Z7G-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "8Z7G", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z7G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of intact S2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z7L", "evidence_id": "EV-PDB-8Z7L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "8Z7L", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z7L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of S-bottom)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z7P", "evidence_id": "EV-PDB-8Z7P-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "8Z7P", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z86", "evidence_id": "EV-PDB-8Z86-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.87}, "provenance": {"deposit_id": "8Z86", "doi": "10.1038/s41392-024-02114-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z86"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.5 RBD in complex with CR9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains F,L,R,X)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z9L", "evidence_id": "EV-PDB-8Z9L-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.598}, "provenance": {"deposit_id": "8Z9L", "doi": "10.1002/pro.70117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z9L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD bound to Rhinolophus affinis ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZBQ", "evidence_id": "EV-PDB-8ZBQ-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "8ZBQ", "doi": "10.1038/s41467-024-51973-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZBQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local map of Omicron Subvariant JN.1 RBD with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZBY", "evidence_id": "EV-PDB-8ZBY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.67}, "provenance": {"deposit_id": "8ZBY", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.1 spike trimer (x2-4P) in complex with 3 D1F6 Fabs (0 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZBZ", "evidence_id": "EV-PDB-8ZBZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.71}, "provenance": {"deposit_id": "8ZBZ", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZBZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with 3 D1F6 Fabs (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZC0", "evidence_id": "EV-PDB-8ZC0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.17}, "provenance": {"deposit_id": "8ZC0", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZC0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with 3 D1F6 Fabs (2 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZC1", "evidence_id": "EV-PDB-8ZC1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.17}, "provenance": {"deposit_id": "8ZC1", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZC1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with D1F6 Fab, focused refinement of RBD region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZC2", "evidence_id": "EV-PDB-8ZC2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.82}, "provenance": {"deposit_id": "8ZC2", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZC2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with D1F6 Fab, head-to-head aggregate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZC3", "evidence_id": "EV-PDB-8ZC3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.69}, "provenance": {"deposit_id": "8ZC3", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZC3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with 3 D1F6 Fabs (1 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZC4", "evidence_id": "EV-PDB-8ZC4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "8ZC4", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with 3 D1F6 Fabs (2 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZC5", "evidence_id": "EV-PDB-8ZC5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.91}, "provenance": {"deposit_id": "8ZC5", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZC5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with D1F6 Fab, focused refinement of RBD region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZC6", "evidence_id": "EV-PDB-8ZC6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.85}, "provenance": {"deposit_id": "8ZC6", "doi": "10.1016/j.celrep.2024.114265", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZC6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with D1F6 Fab, head-to-head aggregate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains B,C,E,G,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZER", "evidence_id": "EV-PDB-8ZER-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8ZER", "doi": "10.1134/S0006297924070083", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZER"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the complex of Wuhan SARS-CoV-2 RBD (319-541) with P2C5 nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,C,D,G,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZES", "evidence_id": "EV-PDB-8ZES-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8ZES", "doi": "10.1134/S0006297924070083", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Wuhan SARS-CoV-2 RBD (333-541) complexed with P2C5 nanobody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHD", "evidence_id": "EV-PDB-8ZHD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "8ZHD", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with two R1-26 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHE", "evidence_id": "EV-PDB-8ZHE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "8ZHE", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with three R1-26 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C,D,E,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHF", "evidence_id": "EV-PDB-8ZHF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.26}, "provenance": {"deposit_id": "8ZHF", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, head-to-head aggregate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHG", "evidence_id": "EV-PDB-8ZHG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "8ZHG", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, focused refinement of RBD-Fab region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHH", "evidence_id": "EV-PDB-8ZHH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.55}, "provenance": {"deposit_id": "8ZHH", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with two H18 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHI", "evidence_id": "EV-PDB-8ZHI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.05}, "provenance": {"deposit_id": "8ZHI", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHJ", "evidence_id": "EV-PDB-8ZHJ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 8.45}, "provenance": {"deposit_id": "8ZHJ", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs, head-to-head aggregate (C1 symmetry)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHK", "evidence_id": "EV-PDB-8ZHK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.3}, "provenance": {"deposit_id": "8ZHK", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs, head-to-head aggregate (C3 symmetry)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6T", "evidence_id": "EV-PDB-8Z6T-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "8Z6T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of XBB.1.16 RBD in complex with antibody CYFN1006-1."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHL", "evidence_id": "EV-PDB-8ZHL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.96}, "provenance": {"deposit_id": "8ZHL", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with two H18 and two R1-32 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHM", "evidence_id": "EV-PDB-8ZHM-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "8ZHM", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHO", "evidence_id": "EV-PDB-8ZHO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54}, "provenance": {"deposit_id": "8ZHO", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S1 in complex with H18 and R1-32 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHP", "evidence_id": "EV-PDB-8ZHP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.66}, "provenance": {"deposit_id": "8ZHP", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dimer of SARS-CoV-2 S1 in complex with H18 and R1-32 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZPP", "evidence_id": "EV-PDB-8ZPP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8ZPP", "doi": "10.1128/jvi.01307-24", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZPP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local CryoEM structure of the SARS-CoV-2 BA.5 in complex with ORB10 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZPQ", "evidence_id": "EV-PDB-8ZPQ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "8ZPQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-Cov-2-BQ1.1-RBD and 70fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,F,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZV9", "evidence_id": "EV-PDB-8ZV9-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8ZV9", "doi": "10.1016/j.jbc.2024.107563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZV9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Complex structure of HLA2402 with recognizing SARS-CoV-2 Y453F epitope NYNYLFRLF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZYF", "evidence_id": "EV-PDB-8ZYF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "8ZYF", "doi": "10.1016/j.ymthe.2025.02.041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZYF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of ZW2G10 Fab in complex with omicron RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ARU", "evidence_id": "EV-PDB-9ARU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "9ARU", "doi": "10.1111/pbi.14458", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ARU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "COVA2-15 fragment antigen binding in complex with SARS-CoV-2 6P-mut7 S protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ASD", "evidence_id": "EV-PDB-9ASD-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9ASD", "doi": "10.1016/j.cell.2024.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ASD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VIR-7229 Fab fragment bound the SARS-CoV-2 BA.2.86 spike trimer (local refinement of the BA 2.86 RBD/VIR-7229 VHVL)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ATO", "evidence_id": "EV-PDB-9ATO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9ATO", "doi": "10.1371/journal.ppat.1012600", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ATO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 spike/Nanosota-3C complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ATP", "evidence_id": "EV-PDB-9ATP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9ATP", "doi": "10.1371/journal.ppat.1012600", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ATP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "local refinement of XBB.1.5 spike/Nanosota-3C complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ATQ", "evidence_id": "EV-PDB-9ATQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9ATQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ATQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 spike/Nanosota-8 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9AU2", "evidence_id": "EV-PDB-9AU2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9AU2", "doi": "10.1016/j.cell.2024.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9AU2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9AYW", "evidence_id": "EV-PDB-9AYW-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9AYW", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9AYW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 1 (S-GSAS-Omicron-EG.5.1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9AYX", "evidence_id": "EV-PDB-9AYX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9AYX", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9AYX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 2 (S-GSAS-Omicron-EG.5.1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9AYY", "evidence_id": "EV-PDB-9AYY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9AYY", "doi": "10.1016/j.molcel.2024.06.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9AYY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron-EG.5.1 3-RBD down Spike Protein Trimer 3 (S-GSAS-Omicron-EG.5.1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B0Y", "evidence_id": "EV-PDB-9B0Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.32}, "provenance": {"deposit_id": "9B0Y", "doi": "10.1016/j.yjsbx.2025.100123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 Spike protein Ectodomain with internal tag, all RBD-down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B2V", "evidence_id": "EV-PDB-9B2V-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "9B2V", "doi": "10.1016/j.yjsbx.2025.100123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B2V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 Spike protein Ectodomain with internal tag, 1RBD-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B4X", "evidence_id": "EV-PDB-9B4X-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "9B4X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B4X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 full-length spike protein with Lys1269Ala and His1271Ala substitutions in the coatomer binding motif, 1RBD-up conformation (SPIKE-AXA)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B82", "evidence_id": "EV-PDB-9B82-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "9B82", "doi": "10.1111/pbi.14458", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B82"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-15"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B8F", "evidence_id": "EV-PDB-9B8F-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.15}, "provenance": {"deposit_id": "9B8F", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B8F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 full-length spike protein with Lys1269Ala and His1271Ala substitutions in the coatomer binding motif, 2RBD-up conformation (SPIKE-AXA)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BD9", "evidence_id": "EV-PDB-9BD9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9BD9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BD9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 full-length WT spike protein, 1RBD-up conformation (SPIKE-WT)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BJ2", "evidence_id": "EV-PDB-9BJ2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9BJ2", "doi": "10.1126/scitranslmed.adq5720", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BJ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer complex with the human neutralizing antibody Fab fragment, C1533 (local refinement of NTD and C1533)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,S)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BJ3", "evidence_id": "EV-PDB-9BJ3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "9BJ3", "doi": "10.1126/scitranslmed.adq5720", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BJ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer complex with the human neutralizing antibody Fab fragment, C1596"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BJ4", "evidence_id": "EV-PDB-9BJ4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9BJ4", "doi": "10.1126/scitranslmed.adq5720", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BJ4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer complex with the human neutralizing antibody Fab fragment, C952"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,D,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BND", "evidence_id": "EV-PDB-9BND-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "9BND", "doi": "10.1038/s42003-025-08819-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BND"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike HexaPro protein in complex with T0A trimeric antagonist"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,D,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BNE", "evidence_id": "EV-PDB-9BNE-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "9BNE", "doi": "10.1038/s42003-025-08819-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BNE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike HexaPro protein in complex with T3A trimeric antagonist"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,D,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BNF", "evidence_id": "EV-PDB-9BNF-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "9BNF", "doi": "10.1038/s42003-025-08819-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BNF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike HexaPro protein in complex with T5A trimeric antagonist"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,D,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BNG", "evidence_id": "EV-PDB-9BNG-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "9BNG", "doi": "10.1038/s42003-025-08819-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BNG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike HexaPro protein in complex with T18A trimeric antagonist"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C44", "evidence_id": "EV-PDB-9C44-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9C44", "doi": "10.1038/s41586-024-08121-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C44"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S + S2L20"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C45", "evidence_id": "EV-PDB-9C45-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9C45", "doi": "10.1038/s41586-024-08121-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C45"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S + S2L20 (local refinement of NTD and S2L20 Fab variable region)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A2G", "CL", "NAG", "SO4", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C6Y", "evidence_id": "EV-PDB-9C6Y-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "9C6Y", "doi": "10.1038/s41564-026-02282-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C6Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 XBB.1.5 RBD bound to COV2-3906 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7X", "evidence_id": "EV-PDB-9C7X-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "9C7X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 antibody 1H06 in complex with a HR2 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CCI", "evidence_id": "EV-PDB-9CCI-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "9CCI", "doi": "10.1016/j.lanmic.2025.101103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CCI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissecting human monoclonal antibody responses from mRNA and protein-based booster vaccinations against XBB1.5 SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CCJ", "evidence_id": "EV-PDB-9CCJ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.37}, "provenance": {"deposit_id": "9CCJ", "doi": "10.1016/j.lanmic.2025.101103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CCJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissecting human monoclonal antibody responses from mRNA and protein-based booster vaccinations against XBB1.5 SARS-CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CFE", "evidence_id": "EV-PDB-9CFE-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "9CFE", "doi": "10.1038/s41467-025-61472-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CFE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Local Refinement of Antibody 19-77 in complex with prefusion SARS-CoV-2 Spike glycoprotein RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CFF", "evidence_id": "EV-PDB-9CFF-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9CFF", "doi": "10.1038/s41467-025-61472-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CFF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Refinement of Antibody 19-77 in complex with SARS-CoV-2 HK.3 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CFG", "evidence_id": "EV-PDB-9CFG-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9CFG", "doi": "10.1038/s41467-025-61472-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CFG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Refinement of Antibody 19-77 R71V in complex with SARS-CoV-2 HK.3 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CB0", "evidence_id": "EV-PDB-9CB0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9CB0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S protein - Accum modified"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2' (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7S", "evidence_id": "EV-PDB-9C7S-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9C7S", "doi": "10.1038/s41564-026-02282-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of SARS-COV-2 (BQ 1.1) RBD in complex with Fab COV2-3891 (local refine)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BLL", "evidence_id": "EV-PDB-9BLL-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "9BLL", "doi": "10.1038/s44298-024-00063-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BLL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM of RBD(EG5.1)/1301B7 Fab Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BEA", "evidence_id": "EV-PDB-9BEA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "9BEA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BEA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 full-length WT spike protein with internal tag, 2RBD-up conformation (SPIKE-WT)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BBK", "evidence_id": "EV-PDB-9BBK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9BBK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BBK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 full-length spike protein with His1271Lys substitution in the coatomer binding motif, 2RBD-up conformation (SPIKE-KxK)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B9U", "evidence_id": "EV-PDB-9B9U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "9B9U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B9U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 full-length spike protein with His1271Lys substitution in the coatomer binding motif, 1RBD-up conformation (SPIKE-KXK)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ATR", "evidence_id": "EV-PDB-9ATR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9ATR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ATR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "local refinement of XBB.1.5 spike/Nanosota-8 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZY3", "evidence_id": "EV-PDB-8ZY3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8ZY3", "doi": "10.1126/sciadv.adr8772", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZY3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Sarbecovirus BANAL-20-236 Spike Trimer in a Locked Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BLA", "EIC", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZY2", "evidence_id": "EV-PDB-8ZY2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8ZY2", "doi": "10.1126/sciadv.adr8772", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZY2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Sarbecovirus BANAL-20-52 Spike Trimer in a Locked Conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZRD", "evidence_id": "EV-PDB-8ZRD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.715}, "provenance": {"deposit_id": "8ZRD", "doi": "10.1016/j.ijbiomac.2024.136403", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZRD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The complex structure of SARS-CoV-2 RBD and llama single-domain antibody S4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZHN", "evidence_id": "EV-PDB-8ZHN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.12}, "provenance": {"deposit_id": "8ZHN", "doi": "10.1038/s41467-024-51770-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZHN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs (one RBD rotated)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FGU", "evidence_id": "EV-PDB-9FGU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "9FGU", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FGU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76-77 (focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FGT", "evidence_id": "EV-PDB-9FGT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9FGT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FGT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76 (focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FGS", "evidence_id": "EV-PDB-9FGS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9FGS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FGS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 (wuhan variant) Spike protein in complex with the single chain fragment scFv41N (focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FGR", "evidence_id": "EV-PDB-9FGR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9FGR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FGR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 (wuhan variant) Spike protein in complex with the single chain fragment scFv76-77 (focused refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FCM", "evidence_id": "EV-PDB-9FCM-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "9FCM", "doi": "10.1038/s41467-025-60250-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FCM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Single-domain antibody binding the SARS-COV2 S2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "EDO", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FC2", "evidence_id": "EV-PDB-9FC2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.21}, "provenance": {"deposit_id": "9FC2", "doi": "10.1080/19420862.2025.2499595", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FC2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of the SARS-CoV-2 receptor binding domain in complex with the neutralizing nanobody 4."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9F9Y", "evidence_id": "EV-PDB-9F9Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9F9Y", "doi": "10.1016/j.str.2024.07.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9F9Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA-2.87.1 Spike ectodomain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELQ", "evidence_id": "EV-PDB-9ELQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.64}, "provenance": {"deposit_id": "9ELQ", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1.11.1+S31 deletion spike protein (closed state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELP", "evidence_id": "EV-PDB-9ELP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.94}, "provenance": {"deposit_id": "9ELP", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1.11.1+S31 deletion spike protein (one RBD up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELO", "evidence_id": "EV-PDB-9ELO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74}, "provenance": {"deposit_id": "9ELO", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1.11+S31 deletion spike protein (closed state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELN", "evidence_id": "EV-PDB-9ELN-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.93}, "provenance": {"deposit_id": "9ELN", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1.11+S31 deletion spike protein (one RBD up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELI", "evidence_id": "EV-PDB-9ELI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "9ELI", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 spike protein (closed state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELH", "evidence_id": "EV-PDB-9ELH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9ELH", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 spike protein (one RBD up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELG", "evidence_id": "EV-PDB-9ELG-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.71}, "provenance": {"deposit_id": "9ELG", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 spike RBD and NTD (local refinement of RBD and NTD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELG", "evidence_id": "EV-PDB-9ELG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.71}, "provenance": {"deposit_id": "9ELG", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 spike RBD and NTD (local refinement of RBD and NTD)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELF", "evidence_id": "EV-PDB-9ELF-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88}, "provenance": {"deposit_id": "9ELF", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ELE", "evidence_id": "EV-PDB-9ELE-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "9ELE", "doi": "10.1016/j.celrep.2025.115941", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ELE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron KP.3.1.1 RBD in complex with human ACE2 (local refinement of RBD and hACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ECZ", "evidence_id": "EV-PDB-9ECZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.89}, "provenance": {"deposit_id": "9ECZ", "doi": "10.1128/mbio.01036-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ECZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with human neutralizing antibody WRAIR-2008 (focused refinement of NTD and WRAIR-2008)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DSL", "evidence_id": "EV-PDB-9DSL-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9DSL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DSL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 S 6P trimer in complex with the cow antibody 99 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DSG", "evidence_id": "EV-PDB-9DSG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "9DSG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DSG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD in complex with the cow antibody P2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C,F,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DHY", "evidence_id": "EV-PDB-9DHY-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9DHY", "doi": "10.1016/j.celrep.2025.115499", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike in complex with antibody Fab COVIC-154"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D8L", "evidence_id": "EV-PDB-9D8L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9D8L", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D8L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "KP.2 SARS-COV-2 Spike 2-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D8K", "evidence_id": "EV-PDB-9D8K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9D8K", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D8K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "KP.2 SARS-COV-2 Spike 1-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D8I", "evidence_id": "EV-PDB-9D8I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9D8I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D8I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "JN.1 SARS-COV-2 Spike 1-up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D8H", "evidence_id": "EV-PDB-9D8H-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9D8H", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D8H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "JN.1 SARS-COV-2 Spike 3-down conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CXE", "evidence_id": "EV-PDB-9CXE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.48}, "provenance": {"deposit_id": "9CXE", "doi": "10.1016/j.yjsbx.2025.100123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CXE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS CoV-2 Spike protein Ectodomain with internal tag, all RBD-down conformation -C1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CVH", "evidence_id": "EV-PDB-9CVH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "9CVH", "doi": "10.1016/j.yjsbx.2025.100123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CVH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein Ecto-domain with internal tag, 1RBD UP, State-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CT2", "evidence_id": "EV-PDB-9CT2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9CT2", "doi": "10.1016/j.yjsbx.2025.100123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CT2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein Ecto-domain with internal tag, All RBD down conformation, State-3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CSS", "evidence_id": "EV-PDB-9CSS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "9CSS", "doi": "10.1016/j.yjsbx.2025.100123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CSS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein Ecto-domain with internal tag, 1UP RBD conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CRI", "evidence_id": "EV-PDB-9CRI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9CRI", "doi": "10.1038/s44318-024-00303-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CRI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Mu (B.1.621) variant 3 closed RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CRH", "evidence_id": "EV-PDB-9CRH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9CRH", "doi": "10.1038/s44318-024-00303-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CRH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Delta (B.1.617.2) variant 3 closed RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CRG", "evidence_id": "EV-PDB-9CRG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9CRG", "doi": "10.1038/s44318-024-00303-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CRG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Gamma (P.1) variant 3 closed RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CRF", "evidence_id": "EV-PDB-9CRF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9CRF", "doi": "10.1038/s44318-024-00303-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CRF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Alpha (B.1.1.7) variant 1 open RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CRE", "evidence_id": "EV-PDB-9CRE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9CRE", "doi": "10.1038/s44318-024-00303-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CRE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Alpha (B.1.1.7) variant 3 closed RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CRD", "evidence_id": "EV-PDB-9CRD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9CRD", "doi": "10.1038/s44318-024-00303-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CRD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: B.1 variant 1 open RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CRC", "evidence_id": "EV-PDB-9CRC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9CRC", "doi": "10.1038/s44318-024-00303-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CRC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: B.1 variant 3 closed RBDs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPY", "evidence_id": "EV-PDB-9CPY-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9CPY", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C11-0860 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPX", "evidence_id": "EV-PDB-9CPX-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9CPX", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0138 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPW", "evidence_id": "EV-PDB-9CPW-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9CPW", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C11-1036 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPV", "evidence_id": "EV-PDB-9CPV-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9CPV", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0614 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPU", "evidence_id": "EV-PDB-9CPU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9CPU", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0304 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPT", "evidence_id": "EV-PDB-9CPT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "9CPT", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-92 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPS", "evidence_id": "EV-PDB-9CPS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "9CPS", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-91 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPR", "evidence_id": "EV-PDB-9CPR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9CPR", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-90 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPQ", "evidence_id": "EV-PDB-9CPQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88}, "provenance": {"deposit_id": "9CPQ", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-44 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CPP", "evidence_id": "EV-PDB-9CPP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.19}, "provenance": {"deposit_id": "9CPP", "doi": "10.1084/jem.20241563", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CPP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-17 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CO9", "evidence_id": "EV-PDB-9CO9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "9CO9", "doi": "10.1371/journal.ppat.1012726", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of JN.1 spike/Nanosota-9 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CO8", "evidence_id": "EV-PDB-9CO8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "9CO8", "doi": "10.1371/journal.ppat.1012726", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CO8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "JN.1 spike/Nanosota-9 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CO7", "evidence_id": "EV-PDB-9CO7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "9CO7", "doi": "10.1371/journal.ppat.1012726", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CO7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of BA.5 spike/Nanosota-9 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CO6", "evidence_id": "EV-PDB-9CO6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "9CO6", "doi": "10.1371/journal.ppat.1012726", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CO6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.5 spike/Nanosota-9 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CFH", "evidence_id": "EV-PDB-9CFH-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9CFH", "doi": "10.1038/s41467-025-61472-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CFH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Refinement of Antibody 19-77 R71V in complex with SARS-CoV-2 JD.1.1 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FR4", "evidence_id": "EV-PDB-9FR4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9FR4", "doi": "10.1186/s12951-025-03243-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FR4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 spike glycoprotein in complex with nanobody 7F (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9GDY", "evidence_id": "EV-PDB-9GDY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9GDY", "doi": "10.1038/s41467-025-59135-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9GDY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike protein Beta Variant at 37C structural flexibility / heterogeneity analyses"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9J66", "evidence_id": "EV-PDB-9J66-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "9J66", "doi": "10.1016/j.antiviral.2025.106082", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9J66"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment CAV-C65 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JTD", "evidence_id": "EV-PDB-9JTD-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.59}, "provenance": {"deposit_id": "9JTD", "doi": "10.1016/j.cellin.2026.100314", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of PCoV-GD receptor binding domain complexed with fox ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JTE", "evidence_id": "EV-PDB-9JTE-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.66}, "provenance": {"deposit_id": "9JTE", "doi": "10.1016/j.cellin.2026.100314", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JTE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain complexed with fox ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein,Fibritin,Expression Tag (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KT3", "evidence_id": "EV-PDB-9KT3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "9KT3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KT3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of EG.5.1 S trimer with 2 down-RBDs complex with antibody CYFN1006-2."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KVF", "evidence_id": "EV-PDB-9KVF-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9KVF", "doi": "10.1073/pnas.2503254122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KVF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 EG.1 spike protein in complex with triple-nAb 4A5, 4C1 and 2E10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KZD", "evidence_id": "EV-PDB-9KZD-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.65}, "provenance": {"deposit_id": "9KZD", "doi": "10.1038/s41467-025-65596-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KZD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The local refined map of SARS-CoV-2 EG.5.1 Variant Spike protein complexed with antibody XGi-171"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KZE", "evidence_id": "EV-PDB-9KZE-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9KZE", "doi": "10.1038/s41467-025-65596-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KZE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The local refined map of SARS-CoV-2 EG.5.1 Variant Spike protein complexed with antibody XGi-183"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KZZ", "evidence_id": "EV-PDB-9KZZ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "9KZZ", "doi": "10.1038/s41467-025-65596-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KZZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 EG.5.1 Variant Spike protein complexed with antibody XGi-171"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L05", "evidence_id": "EV-PDB-9L05-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "9L05", "doi": "10.1038/s41467-025-65596-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L05"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The local refined map of SARS-CoV-2 EG.5.1 Variant Spike protein complexed with antibody XGi-198"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L07", "evidence_id": "EV-PDB-9L07-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.28}, "provenance": {"deposit_id": "9L07", "doi": "10.1038/s41467-025-65596-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L07"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The local refined map of SARS-CoV-2 EG.5.1 Variant Spike protein complexed with antibody XGi-203"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L15", "evidence_id": "EV-PDB-9L15-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9L15", "doi": "10.1038/s41467-025-65596-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L15"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 EG.5.1 Variant Spike protein complexed with antibody XGi-203"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L3I", "evidence_id": "EV-PDB-9L3I-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9L3I", "doi": "10.1038/s41467-026-68462-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L3I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 BA.2.75 Spike Protein complex with a potent broad-spectrum macrocyclic peptide inhibitor 6L3-3P11K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L3Q", "evidence_id": "EV-PDB-9L3Q-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9L3Q", "doi": "10.1038/s41467-026-68462-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L3Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 PT Spike Protein complex with a potent broad-spectrum macrocyclic peptide inhibitor 6L3-3P11K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LBS", "evidence_id": "EV-PDB-9LBS-6", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "9LBS", "doi": "10.1016/j.str.2025.04.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LBS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Omicron BA.1 RBD complexed with ConBA-998,S309 and S304Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LAE", "evidence_id": "EV-PDB-9LAE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "9LAE", "doi": "10.1038/s41467-023-39265-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LAE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Locally refined region of SARS-CoV-2 spike in complex with antibodies 9G11 and 3E2."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L6C", "evidence_id": "EV-PDB-9L6C-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "9L6C", "doi": "10.1128/jvi.01844-24", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L6C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Delta RBD complexed with ConD-852, P2C-1F11 and S304 Fabs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L2L", "evidence_id": "EV-PDB-9L2L-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9L2L", "doi": "10.1038/s41467-025-65596-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L2L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 EG.5.1 Variant Spike protein complexed with antibody XGi-198"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KWY", "evidence_id": "EV-PDB-9KWY-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "9KWY", "doi": "10.1371/journal.ppat.1013744", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KWY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 RBD in complex with ACE2 and mAb 1C4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KVT", "evidence_id": "EV-PDB-9KVT-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "9KVT", "doi": "10.1371/journal.ppat.1013744", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KVT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 BA.2 spike protein in complex with triple-nAb 8H12, 3E2 and 1C4 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KVQ", "evidence_id": "EV-PDB-9KVQ-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "9KVQ", "doi": "10.1371/journal.ppat.1013744", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 BA.1 spike protein in complex with three-nAb 8H12, 3E2 and 1C4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KVK", "evidence_id": "EV-PDB-9KVK-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "9KVK", "doi": "10.1371/journal.ppat.1013744", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KVK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with three-nAb 8H12, 3E2 and 1C4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KVJ", "evidence_id": "EV-PDB-9KVJ-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.82}, "provenance": {"deposit_id": "9KVJ", "doi": "10.1371/journal.ppat.1013744", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KVJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 BA.5 spike protein in complex with nAb 1C4 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KVE", "evidence_id": "EV-PDB-9KVE-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9KVE", "doi": "10.1073/pnas.2503254122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KVE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with triple-nAb 4H1, 4A5 and 4C1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KUD", "evidence_id": "EV-PDB-9KUD-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "9KUD", "doi": "10.1016/j.str.2025.07.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KUD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 JN.1 variant RBD complexed with squirrel ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K75", "evidence_id": "EV-PDB-9K75-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "9K75", "doi": "10.1128/jvi.01007-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K75"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 related bat coronavirus BANAL-103 spike in the closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EIC", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K6Z", "evidence_id": "EV-PDB-9K6Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "9K6Z", "doi": "10.1128/jvi.01007-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K6Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 related bat coronavirus BANAL-52 spike in the locked state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K6Y", "evidence_id": "EV-PDB-9K6Y-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67}, "provenance": {"deposit_id": "9K6Y", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K6Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with H4 Fab (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K6J", "evidence_id": "EV-PDB-9K6J-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "9K6J", "doi": "10.1002/advs.202517192", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K6J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 WT RBD bound with P5-1C8 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JS4", "evidence_id": "EV-PDB-9JS4-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9JS4", "doi": "10.1073/pnas.2406659122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JS4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of neutralizing antibody 8G3 in complex with BA.1 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JRC", "evidence_id": "EV-PDB-9JRC-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "9JRC", "doi": "10.1016/j.str.2025.07.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JRC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor-binding domain complexed with squirrel ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JR5", "evidence_id": "EV-PDB-9JR5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.414}, "provenance": {"deposit_id": "9JR5", "doi": "10.1016/j.str.2025.07.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JR5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of PCoV-GD receptor-binding domain complexed with squirrel ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JEB", "evidence_id": "EV-PDB-9JEB-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "9JEB", "doi": "10.1038/s41467-026-70553-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv N1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IB1", "evidence_id": "EV-PDB-9IB1-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9IB1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IB1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM focus map of prefusion SARS-CoV-2 spike (RBDs: 1 up & 2 down) bound to RBD-targeting MO176-117 antibody"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LOZ", "evidence_id": "EV-PDB-9LOZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "9LOZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LOZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 JN.1 RBD in complex with F61R2-780 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LP0", "evidence_id": "EV-PDB-9LP0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "9LP0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LP0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 KP.3.1.1 spike glycoprotein in complex with F61R2-780 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LP1", "evidence_id": "EV-PDB-9LP1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "9LP1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LP1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 KP.3.1.1 RBD in complex with F61R2-780 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EZO", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LVS", "evidence_id": "EV-PDB-9LVS-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9LVS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LVS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 spike protein in complex with S416"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LYO", "evidence_id": "EV-PDB-9LYO-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "9LYO", "doi": "10.1016/j.bbrc.2025.151558", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha SARS-CoV-2 spike protein in complex with REGN10987 Fab homologue."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9M3F", "evidence_id": "EV-PDB-9M3F-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "9M3F", "doi": "10.1016/j.celrep.2025.116220", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9M3F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Rc-o319 RBD/R. cornutus ACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,C,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MI3", "evidence_id": "EV-PDB-9MI3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.23}, "provenance": {"deposit_id": "9MI3", "doi": "10.1128/mbio.01036-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MI3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike protein in complex with neutralizing human antibody WRAIR-2008"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ML4", "evidence_id": "EV-PDB-9ML4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9ML4", "doi": "10.1073/pnas.2501637122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ML4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike 6P in complex with the rabbit M8b-A10 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ML6", "evidence_id": "EV-PDB-9ML6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9ML6", "doi": "10.1073/pnas.2501637122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ML6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike 6P in complex with the rabbit M8b-C9 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ML9", "evidence_id": "EV-PDB-9ML9-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "9ML9", "doi": "10.1073/pnas.2501637122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ML9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 RBD in complex with the rabbit M8b-C9 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MR1", "evidence_id": "EV-PDB-9MR1-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.59}, "provenance": {"deposit_id": "9MR1", "doi": "10.1084/jem.20251146", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MR1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 monomer in complex with R125-61 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MR2", "evidence_id": "EV-PDB-9MR2-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.79}, "provenance": {"deposit_id": "9MR2", "doi": "10.1084/jem.20251146", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MR2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 monomer in complex with NICA01A-1401 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9NFT", "evidence_id": "EV-PDB-9NFT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9NFT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9NFT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PRO-37587 bound to SARS-CoV-2 Spike protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2 (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9NHP", "evidence_id": "EV-PDB-9NHP-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.93}, "provenance": {"deposit_id": "9NHP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9NHP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "GB-0669 Fab: S2 stem helix peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9NVG", "evidence_id": "EV-PDB-9NVG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9NVG", "doi": "10.1038/s41564-026-02282-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9NVG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.1 spike RBD bound to COV2-3835 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9NXY", "evidence_id": "EV-PDB-9NXY-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "9NXY", "doi": "10.1038/s41467-025-66693-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9NXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 spike S2' trimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9O5T", "evidence_id": "EV-PDB-9O5T-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9O5T", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9O5T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric SARS-CoV-2 RBD complexed with chimeric Rhinolophus sinicus ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9O5V", "evidence_id": "EV-PDB-9O5V-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "9O5V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9O5V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric BANAL-52 RBD complexed with chimeric Rhinolophus sinicus ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OG4", "evidence_id": "EV-PDB-9OG4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "9OG4", "doi": "10.1128/jvi.01034-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OG4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-COV-2-6P-MUT7 S PROTEIN-DY-III-281 complex closed conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OG5", "evidence_id": "EV-PDB-9OG5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9OG5", "doi": "10.1128/jvi.01034-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OG5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-COV-2-6P-MUT7 S PROTEIN-DY-III-281 complex 1 RBD up conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OG6", "evidence_id": "EV-PDB-9OG6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "9OG6", "doi": "10.1128/jvi.01034-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OG6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Apo SARS-COV-2-6P-MUT7 S PROTEIN closed conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "GOL", "PEG", "PGE", "SO4", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 receptor binding domain (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PSO", "evidence_id": "EV-PDB-9PSO-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.62}, "provenance": {"deposit_id": "9PSO", "doi": "10.1016/j.celrep.2026.117137", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PSO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies BoWLB-622 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "EDO", "NAG", "PEG", "PGE", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 receptor binding domain (chains T,U)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PSP", "evidence_id": "EV-PDB-9PSP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "9PSP", "doi": "10.1016/j.celrep.2026.117137", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PSP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies BoWLB-1173 and CC12.3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PW4", "evidence_id": "EV-PDB-9PW4-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "9PW4", "doi": "10.1016/j.celrep.2025.116800", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PW4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of V30V4 in complex with SARS-CoV-2 spike"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SAT", "evidence_id": "EV-PDB-9SAT-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "9SAT", "doi": "10.1073/pnas.2523864123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SAT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 Neutralization"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "LI", "NAG", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SBB", "evidence_id": "EV-PDB-9SBB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.12}, "provenance": {"deposit_id": "9SBB", "doi": "10.1073/pnas.2523864123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SBB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 Neutralization"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9T74", "evidence_id": "EV-PDB-9T74-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "9T74", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9T74"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "2'-fluoro-modified pyrimidine (FY) RNA aptamer binding to the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. (focus map: RBD-aptamer)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TVT", "evidence_id": "EV-PDB-9TVT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "9TVT", "doi": "10.1016/j.ijbiomac.2026.153102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TVT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD-beta variant) in complex with 3D2 Fab and 1D1 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UE6", "evidence_id": "EV-PDB-9UE6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9UE6", "doi": "10.1038/s41467-025-66018-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UE6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 KP.2 spike RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2',Chimeric protein mimic of SARS-CoV-2 Spike HR1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RN6", "evidence_id": "EV-PDB-9RN6-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "9RN6", "doi": "10.1016/j.ijbiomac.2025.150022", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a protein mimic of SARS-CoV-2 spike's HR1 domain in complex with two nanobodies bound to different epitopes"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ML5", "evidence_id": "EV-PDB-9ML5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9ML5", "doi": "10.1073/pnas.2501637122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ML5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 Spike 6P in complex with the rabbit M8b-B8 Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LDS", "evidence_id": "EV-PDB-9LDS-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "9LDS", "doi": "10.1371/journal.ppat.1013034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LDS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of nanobody H145 bound to SARS-CoV-2 spike stem-helix"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LD2", "evidence_id": "EV-PDB-9LD2-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "9LD2", "doi": "10.1038/s41586-026-10462-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LD2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 wide-type S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab (focused refinement of the S2-76E1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UG3", "evidence_id": "EV-PDB-9UG3-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "9UG3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 spike-CD147 complex at 3.75 Angstroms resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UHF", "evidence_id": "EV-PDB-9UHF-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.18}, "provenance": {"deposit_id": "9UHF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UHF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "JN.1 RBD in complex with antibody BA5-12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UHG", "evidence_id": "EV-PDB-9UHG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.91}, "provenance": {"deposit_id": "9UHG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UHG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "JN.1 RBD in complex with antibody BA5-12-CDR1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UHH", "evidence_id": "EV-PDB-9UHH-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.05}, "provenance": {"deposit_id": "9UHH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UHH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "WT RBD in complex with antibody BA5-12-GR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UHQ", "evidence_id": "EV-PDB-9UHQ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.62}, "provenance": {"deposit_id": "9UHQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UHQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of JN.1 spike in complex with antibody BA5-39"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UXD", "evidence_id": "EV-PDB-9UXD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "9UXD", "doi": "10.1016/j.celrep.2025.115964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV2 Spike protein with Fab fragment antibody KXD355,state1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UXS", "evidence_id": "EV-PDB-9UXS-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9UXS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UXS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The local refine of 3D reconstruction of the complex formed by SARS-CoV2 BA.1 spike glycoprotein and a single-domain antibody"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UYD", "evidence_id": "EV-PDB-9UYD-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9UYD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UYD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Ancestral strain spike S-cred"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VFX", "evidence_id": "EV-PDB-9VFX-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9VFX", "doi": "10.1016/j.mucimm.2026.100392", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VFX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike di-trimer of RBD and NTD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VFX", "evidence_id": "EV-PDB-9VFX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9VFX", "doi": "10.1016/j.mucimm.2026.100392", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VFX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike di-trimer of RBD and NTD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VG7", "evidence_id": "EV-PDB-9VG7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "9VG7", "doi": "10.1016/j.celrep.2025.116220", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VG7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Rc-o319 Ectodomain trimer"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WIG", "evidence_id": "EV-PDB-9WIG-7", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.93}, "provenance": {"deposit_id": "9WIG", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WIG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the PT NTD-C1536-CoV2-3434-BLN8 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WLB", "evidence_id": "EV-PDB-9WLB-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.74}, "provenance": {"deposit_id": "9WLB", "doi": "10.1016/j.celrep.2026.117582", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WLB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement region of SARS-CoV-2 spike RBD in complex with antibodies S309 and CT1-1."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S2' (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WPP", "evidence_id": "EV-PDB-9WPP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9WPP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WPP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 spike protein HR1 in complex with a designed peptide inhibitor dP-S2FI-0087 at 3.1 angstrom resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WSP", "evidence_id": "EV-PDB-9WSP-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.55}, "provenance": {"deposit_id": "9WSP", "doi": "10.1021/acsinfecdis.5c00479", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WSP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS CoV2 S protein with stabilising mutations"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9X9Z", "evidence_id": "EV-PDB-9X9Z-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "9X9Z", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9X9Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Omicron BA.2.86 variant Spike N-terminal domain(NTD)in complex with the antibody Fab fragment, C1717"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XA4", "evidence_id": "EV-PDB-9XA4-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.52}, "provenance": {"deposit_id": "9XA4", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XA4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Omicron BA.4/5 Spike N-terminal domain(NTD) in complex with the AC2 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XAR", "evidence_id": "EV-PDB-9XAR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "9XAR", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XAR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 Spike N-terminal domain(NTD) in complex with the C1624 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XGO", "evidence_id": "EV-PDB-9XGO-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.77}, "provenance": {"deposit_id": "9XGO", "doi": "10.1080/22221751.2024.2412990", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XGO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XGO", "evidence_id": "EV-PDB-9XGO-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.77}, "provenance": {"deposit_id": "9XGO", "doi": "10.1080/22221751.2024.2412990", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XGO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XGX", "evidence_id": "EV-PDB-9XGX-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9XGX", "doi": "10.1002/jmv.70969", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XGX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 receptor binding domain in complex with SR-23 Fab (local refinement of RBD and Fv)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XHZ", "evidence_id": "EV-PDB-9XHZ-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.28}, "provenance": {"deposit_id": "9XHZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C092 Fab and ACE2 (2 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI0", "evidence_id": "EV-PDB-9XI0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.98}, "provenance": {"deposit_id": "9XI0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C092 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI1", "evidence_id": "EV-PDB-9XI1-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.58}, "provenance": {"deposit_id": "9XI1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with C092 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI2", "evidence_id": "EV-PDB-9XI2-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "9XI2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with C807 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI3", "evidence_id": "EV-PDB-9XI3-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.74}, "provenance": {"deposit_id": "9XI3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C807 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI4", "evidence_id": "EV-PDB-9XI4-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "9XI4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with BD56-104 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI6", "evidence_id": "EV-PDB-9XI6-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9XI6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with BD56-597 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI7", "evidence_id": "EV-PDB-9XI7-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "9XI7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with BD56-597 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI9", "evidence_id": "EV-PDB-9XI9-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.93}, "provenance": {"deposit_id": "9XI9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron LP.8.1 spike trimer (S-6P) in complex with 3 ZL58 Fabs and 3 ZL525 Fabs, focused refinement of RBD and Fab region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XID", "evidence_id": "EV-PDB-9XID-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "9XID", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XID"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron JD.1.1 spike trimer (S-6P) in complex with 3 R102-9 Fabs and 3 C092 Fabs, focused refinement of RBD and Fab region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Stem helix peptide of Spike protein S2' (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YJI", "evidence_id": "EV-PDB-9YJI-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "9YJI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YJI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with monoclonal antibody CC65.1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YOK", "evidence_id": "EV-PDB-9YOK-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "9YOK", "doi": "10.1371/journal.ppat.1014071", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YOK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Fab-14/SARS-CoV-2 D614G spike complex, Mode I conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YNX", "evidence_id": "EV-PDB-9YNX-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "9YNX", "doi": "10.1371/journal.ppat.1014071", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YNX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of Fab-14/SARS-CoV-2 D614G spike complex, Mode IV, Subgroup I conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Y5Y", "evidence_id": "EV-PDB-9Y5Y-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "9Y5Y", "doi": "10.1101/2025.10.21.683815", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Y5Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the Omicron Spike RBD bound by the monobody s19382 (local refinement from dimerized Spike protein ECDs)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XIC", "evidence_id": "EV-PDB-9XIC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "9XIC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XIC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron JD.1.1 spike trimer (S-6P) in complex with 3 R102-9 Fabs and 3 C092 Fabs (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI5", "evidence_id": "EV-PDB-9XI5-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "9XI5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with BD56-104 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XHY", "evidence_id": "EV-PDB-9XHY-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "9XHY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with C092 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XGW", "evidence_id": "EV-PDB-9XGW-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9XGW", "doi": "10.1002/jmv.70969", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 receptor binding domain in complex with CS-42 Fab (local refinement of RBD and Fv)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains I,J,K,L)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XAW", "evidence_id": "EV-PDB-9XAW-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "9XAW", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XAW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the SARS-CoV-2 Spike N-terminal domain(NTD) in complex with the BLN8 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XA5", "evidence_id": "EV-PDB-9XA5-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "9XA5", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XA5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Omicron BA.4/5 Spike N-terminal domain(NTD) in complex with the AC8 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike glycoprotein (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XA0", "evidence_id": "EV-PDB-9XA0-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "9XA0", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XA0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the Omicron KP.3.1.1 variant Spike N-terminal domain(NTD)in complex with the C1717 Fab and S2L20 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9X9T", "evidence_id": "EV-PDB-9X9T-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "9X9T", "doi": "10.1073/pnas.2537053123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9X9T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of SARS-CoV-2 KP.3.1.1 RBD with BD57-2704 and AB2-122 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "dP-S2FI-0089,Spike protein S2' (chains A,C,E,G,I,K)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WP8", "evidence_id": "EV-PDB-9WP8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9WP8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the SARS-CoV-2 spike protein HR1 in complex with a designed peptide inhibitor dP-S2FI-0089 at 3.1 angstrom resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6U", "evidence_id": "EV-PDB-9W6U-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "9W6U", "doi": "10.1073/pnas.2535385123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the PT NTD-C1554-C1540 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W14", "evidence_id": "EV-PDB-9W14-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33}, "provenance": {"deposit_id": "9W14", "doi": "10.1371/journal.ppat.1013744", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 WT spike protein in complex with nAb 1C4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VLT", "evidence_id": "EV-PDB-9VLT-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.65}, "provenance": {"deposit_id": "9VLT", "doi": "10.1038/s41586-026-10462-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VLT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UXE", "evidence_id": "EV-PDB-9UXE-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.17}, "provenance": {"deposit_id": "9UXE", "doi": "10.1016/j.celrep.2025.115964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UXE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV2 Spike protein with Fab fragment antibody KXD355,state2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UTF", "evidence_id": "EV-PDB-9UTF-2", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9UTF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UTF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SARS-CoV-2 S receptor-binding domain (RBD) in complex XG83 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UPR", "evidence_id": "EV-PDB-9UPR-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "9UPR", "doi": "10.1016/j.ymthe.2026.05.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the N-terminal domain of Omicron BA.1 in complex with nanobody N103 and S2L20 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Z18", "evidence_id": "EV-PDB-9Z18-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9Z18", "doi": "10.1371/journal.ppat.1014391", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Z18"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike S2 in complex with antibody N6-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZT8", "evidence_id": "EV-PDB-9ZT8-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "9ZT8", "doi": "10.64898/2026.02.18.706653", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZT8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Stabilized SARS-CoV-2 S2 apo"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZT7", "evidence_id": "EV-PDB-9ZT7-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "9ZT7", "doi": "10.64898/2026.02.18.706653", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZT7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 in complex with COV2-2509"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZT6", "evidence_id": "EV-PDB-9ZT6-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "9ZT6", "doi": "10.64898/2026.02.18.706653", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZT6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 in complex with polyclonal Fab-B_Donor8"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZT5", "evidence_id": "EV-PDB-9ZT5-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.21}, "provenance": {"deposit_id": "9ZT5", "doi": "10.64898/2026.02.18.706653", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZT5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 in complex with polyclonal Fab-B_Donor3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "PEG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZDU", "evidence_id": "EV-PDB-9ZDU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9ZDU", "doi": "10.1073/pnas.2536870123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZDU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD in complex with human Ab401 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZBY", "evidence_id": "EV-PDB-9ZBY-5", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.73}, "provenance": {"deposit_id": "9ZBY", "doi": "10.1002/advs.76522", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 Omicron BA.1 receptor binding domain in complex with antibodies HB148-M4 and LY-CoV1404"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Spike protein S1 (chains C,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZBW", "evidence_id": "EV-PDB-9ZBW-4", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9ZBW", "doi": "10.1002/advs.76522", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZBW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies HB148 and LY-CoV1404"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Z80", "evidence_id": "EV-PDB-9Z80-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.17}, "provenance": {"deposit_id": "9Z80", "doi": "10.64898/2026.02.18.706653", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Z80"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 in complex with polyclonal Fab_Donor1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "SPIKE PROTEIN (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Z3K", "evidence_id": "EV-PDB-9Z3K-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9Z3K", "doi": "10.1038/s41594-026-01801-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Z3K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike protein S2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Z12", "evidence_id": "EV-PDB-9Z12-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9Z12", "doi": "10.1371/journal.ppat.1014391", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Z12"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike S2 in complex with antibody B3-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YYV", "evidence_id": "EV-PDB-9YYV-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9YYV", "doi": "10.1038/s41594-026-01801-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YYV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YYU", "evidence_id": "EV-PDB-9YYU-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9YYU", "doi": "10.1038/s41594-026-01801-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YYU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (Fab local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1CZB", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YVI", "evidence_id": "EV-PDB-9YVI-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "9YVI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YVI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BA.5 spike in complex with S22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YTC", "evidence_id": "EV-PDB-9YTC-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "9YTC", "doi": "10.1073/pnas.2537053123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YTC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron neutralizing antibody S212 with BA.5 RBD and SP1-77 Fab complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YTA", "evidence_id": "EV-PDB-9YTA-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "9YTA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YTA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron neutralizing antibody L52 with BA.5 RBD and SP1-77 Fab complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YSG", "evidence_id": "EV-PDB-9YSG-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9YSG", "doi": "10.1073/pnas.2537053123", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YSG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron neutralizing antibody AB2-122 with BA.5 RBD and SP1-77 Fab complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YPR", "evidence_id": "EV-PDB-9YPR-1", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "9YPR", "doi": "10.1371/journal.ppat.1014071", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Fab-14/SARS-CoV-2 D614G spike complex, Mode IV, subgroup I conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YPB", "evidence_id": "EV-PDB-9YPB-3", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9YPB", "doi": "10.1371/journal.ppat.1014071", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YPB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Fab-14/SARS-CoV-2 D614G spike complex, Mode IV, subgroup II conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30842", "evidence_id": "EV-BMRB-30842", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30842", "doi": "10.13018/BMR30842", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30842"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "SARS-CoV-2 spike Protein TM domain"}
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{"conditions": {"applied_force_pn": null, "buffer": "phosphate buffered saline", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 7.4, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Spike glycoprotein (ACE2 receptor binding domain)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDQ39/", "evidence_id": "EV-SASBDB-SASDQ39", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "radius_of_gyration", "uncertainty": 0.006, "unit": "nm", "value": 3.011}, "provenance": {"deposit_id": "SASDQ39", "doi": "10.1038/s42003-023-05416-7", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDQ39/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Form factor determination of biological molecules with X-ray free electron laser small-angle scattering (XFEL-SAS)."}
{"conditions": {"applied_force_pn": null, "buffer": "50mM Tris, 200mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Angiotensin converting Enzyme 2"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 21.36 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Receptor Binding Domain with Angiotensin converting Enzyme 2", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXX6/", "evidence_id": "EV-SASBDB-SASDXX6", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "radius_of_gyration", "uncertainty": 0.562, "unit": "nm", "value": 6.709}, "provenance": {"deposit_id": "SASDXX6", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXX6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "ACE2 RBD Complex"}
{"conditions": {"applied_force_pn": null, "buffer": "50mM Tris, 200mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.06 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Receptor Binding Domain of SARS CoV-2", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXZ6/", "evidence_id": "EV-SASBDB-SASDXZ6", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "radius_of_gyration", "uncertainty": 0.15, "unit": "nm", "value": 2.942}, "provenance": {"deposit_id": "SASDXZ6", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXZ6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Receptor Binding Domain of SARS CoV-2"}
{"conditions": {"applied_force_pn": null, "buffer": "50mM Tris, 150mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Angiotensin-converting enzyme 2"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 11.42 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Spike glycoprotein with Angiotensin-converting enzyme 2", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDYG7/", "evidence_id": "EV-SASBDB-SASDYG7", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "radius_of_gyration", "uncertainty": 0.896, "unit": "nm", "value": 4.393}, "provenance": {"deposit_id": "SASDYG7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDYG7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "ACE 2 RBD with Umifenovir"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 70-79; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r001", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 10}, "provenance": {"deposit_id": "DP02772r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 70-79"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 144-164; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r002", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 21}, "provenance": {"deposit_id": "DP02772r002", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 144-164"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 173-185; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r003", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 13}, "provenance": {"deposit_id": "DP02772r003", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 173-185"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 246-262; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r004", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 17}, "provenance": {"deposit_id": "DP02772r004", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 246-262"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 469-488; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r005", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 20}, "provenance": {"deposit_id": "DP02772r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 469-488"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 621-640; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r006", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 20}, "provenance": {"deposit_id": "DP02772r006", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 621-640"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 677-687; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r007", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 11}, "provenance": {"deposit_id": "DP02772r007", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 677-687"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 828-853; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r008", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 26}, "provenance": {"deposit_id": "DP02772r008", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 828-853"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1148-1273; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32155444", "evidence_id": "EV-DISPROT-DP02772r009", "mappings": [], "molecule_id": "P0DTC2", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 126}, "provenance": {"deposit_id": "DP02772r009", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02772"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02772: disorder, residues 1148-1273"}
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alternate", "position": 686, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine; alternate", "position": 702, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine", "position": 711, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by CK1 and PDPK1", "position": 713, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; alternate", "position": 717, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine", "position": 720, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by CK1 and PDPK1", "position": 721, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 726, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by CaMK2 and TTBK1", "position": 733, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by PDPK1 and TTBK1", "position": 739, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine; by TTBK1", "position": 744, "source": "UniProtKB"}], "molecule_id": "P10636", "molecule_type": "protein", "name": "Microtubule-associated protein tau", "organism": {"name": "Homo sapiens", "taxon_id": 9606}, "provenance": {"deposit_id": "P10636", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10636/entry"}, "record_type": "molecule", "sequence": "MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKYVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL", "sequence_length": 758}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/10IK", "evidence_id": "EV-PDB-10IK-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "10IK", "doi": "10.64898/2026.02.12.705620", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/10IK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S305I Frontotemporal Lobar Degeneration (FTLD) type II tau filament"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/10NQ", "evidence_id": "EV-PDB-10NQ-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.61}, "provenance": {"deposit_id": "10NQ", "doi": "10.1038/s41594-026-01879-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/10NQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "u-VT Ic tau filament from VT Case 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "MICROTUBULE-ASSOCIATED PROTEIN TAU (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1I8H", "evidence_id": "EV-PDB-1I8H-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1I8H", "doi": "10.1074/jbc.M010327200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1I8H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH HUMAN TAU PHOSPHOTHREONINE PEPTIDE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/28LO", "evidence_id": "EV-PDB-28LO-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "28LO", "doi": "10.1007/s00401-026-03049-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/28LO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau filament with G272V mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "VQIVYK peptide corresponding to residues 306-311 in the tau protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ON9", "evidence_id": "EV-PDB-2ON9-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a filament or fibril.", "rule": "tau-filament-title", "state_id": "tau-filament", "who": "rule:tau-filament-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.51}, "provenance": {"deposit_id": "2ON9", "doi": "10.1038/nature05695", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ON9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of an amyloid forming peptide VQIVYK from the repeat region of Tau"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/37VX", "evidence_id": "EV-PDB-37VX-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "37VX", "doi": "10.1016/j.bbrc.2026.154679", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/37VX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CTE Type I structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/37VY", "evidence_id": "EV-PDB-37VY-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "37VY", "doi": "10.1016/j.bbrc.2026.154679", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/37VY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CTE Type I-like structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "PGE", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Microtubule-associated protein tau (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4TQE", "evidence_id": "EV-PDB-4TQE-3", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "4TQE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4TQE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of tau peptide in complex with Tau5 antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Microtubule-associated protein (chains P,X,Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5DMG", "evidence_id": "EV-PDB-5DMG-3", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "5DMG", "doi": "10.1080/19420862.2015.1117720", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5DMG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY STRUCTURE OF THE FAB FRAGMENT OF THE ANTI TAU ANTIBODY RB86 IN COMPLEX WITH THE PHOSPHORYLATED TAU PEPTIDE (416-430)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,E,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MP1", "evidence_id": "EV-PDB-5MP1-3", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "5MP1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MP1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 7.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5O3L", "evidence_id": "EV-PDB-5O3L-1", "mappings": [{"confidence": "high", "justification": "Paired helical filament, cryo-EM.", "rule": "curator_assignment", "state_id": "tau-filament", "who": "curator:draft (unreviewed)"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "5O3L", "doi": "10.1038/nature23002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5O3L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Paired helical filament in Alzheimer's disease brain"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Microtubule-associated protein tau (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NP8", "evidence_id": "EV-PDB-4NP8-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.51}, "provenance": {"deposit_id": "4NP8", "doi": "10.1038/nsmb.1643", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of an amyloid forming peptide VQIVYK from the second repeat region of tau (alternate polymorph)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q88", "evidence_id": "EV-PDB-8Q88-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "8Q88", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q88"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-LIA2 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q7T", "evidence_id": "EV-PDB-8Q7T-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8Q7T", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q7T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA11"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q7P", "evidence_id": "EV-PDB-8Q7P-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.28}, "provenance": {"deposit_id": "8Q7P", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA8 (intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q7M", "evidence_id": "EV-PDB-8Q7M-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "8Q7M", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q7M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA7 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q7L", "evidence_id": "EV-PDB-8Q7L-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "8Q7L", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q7L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA6 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q7F", "evidence_id": "EV-PDB-8Q7F-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "8Q7F", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q7F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q2L", "evidence_id": "EV-PDB-8Q2L-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8Q2L", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q2L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q2K", "evidence_id": "EV-PDB-8Q2K-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88}, "provenance": {"deposit_id": "8Q2K", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q2K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q2J", "evidence_id": "EV-PDB-8Q2J-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.23}, "provenance": {"deposit_id": "8Q2J", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q2J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-MIA2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q27", "evidence_id": "EV-PDB-8Q27-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "8Q27", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q27"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau: AD-MIA1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PPO", "evidence_id": "EV-PDB-8PPO-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "8PPO", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PPO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "First Intermediate Amyloid (FIA) - Tau"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "tau protein (chains A)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZZX", "evidence_id": "EV-PDB-8ZZX-1", "mappings": [], "molecule_id": "P10636", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8ZZX", "doi": "10.1016/j.str.2019.09.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZZX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Insight into the structure of the unstructured tau protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TTN", "evidence_id": "EV-PDB-8TTN-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "8TTN", "doi": "10.1073/pnas.2316175121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TTN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SEH", "evidence_id": "EV-PDB-8SEH-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8SEH", "doi": "10.1038/s41594-024-01252-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SEH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PHF Tau from Down Syndrome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8R3T", "evidence_id": "EV-PDB-8R3T-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8R3T", "doi": "10.1038/s41467-023-39314-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8R3T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cofactor-free Tau 4R2N isoform"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QJJ", "evidence_id": "EV-PDB-8QJJ-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "8QJJ", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QJJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CTE type II (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Microtubule-associated protein tau (chains C,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QDV", "evidence_id": "EV-PDB-8QDV-2", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8QDV", "doi": "10.1038/s42003-025-08548-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QDV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of 14-3-3 zeta delta C with the bivalent tau-pS214-pS324 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QCR", "evidence_id": "EV-PDB-8QCR-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "8QCR", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QCR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA12 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QCP", "evidence_id": "EV-PDB-8QCP-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.21}, "provenance": {"deposit_id": "8QCP", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QCP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - AD-LIA8 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9O", "evidence_id": "EV-PDB-8Q9O-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8Q9O", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CTE tau intermediate amyloid (LIA-17)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9M", "evidence_id": "EV-PDB-8Q9M-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "8Q9M", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-type I (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9L", "evidence_id": "EV-PDB-8Q9L-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "8Q9L", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-LIA14 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9K", "evidence_id": "EV-PDB-8Q9K-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8Q9K", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-LIA13 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9J", "evidence_id": "EV-PDB-8Q9J-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "8Q9J", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-LIA7 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9I", "evidence_id": "EV-PDB-8Q9I-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.56}, "provenance": {"deposit_id": "8Q9I", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-LIA6 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9H", "evidence_id": "EV-PDB-8Q9H-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.18}, "provenance": {"deposit_id": "8Q9H", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-LIA4 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9G", "evidence_id": "EV-PDB-8Q9G-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "8Q9G", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-LIA5 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,c)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9F", "evidence_id": "EV-PDB-8Q9F-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.91}, "provenance": {"deposit_id": "8Q9F", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-LIA3 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9E", "evidence_id": "EV-PDB-8Q9E-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "8Q9E", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA18 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9D", "evidence_id": "EV-PDB-8Q9D-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "8Q9D", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA15 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9C", "evidence_id": "EV-PDB-8Q9C-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8Q9C", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA14 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q9B", "evidence_id": "EV-PDB-8Q9B-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8Q9B", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q9B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA13 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q99", "evidence_id": "EV-PDB-8Q99-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8Q99", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q99"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA10 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q98", "evidence_id": "EV-PDB-8Q98-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "8Q98", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q98"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA8 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q97", "evidence_id": "EV-PDB-8Q97-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "8Q97", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q97"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA9 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q92", "evidence_id": "EV-PDB-8Q92-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "8Q92", "doi": "10.1186/s40478-023-01658-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q92"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "P301S Tau Filaments from the Brains of PS19 Transgenic Mouse Line"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q8Z", "evidence_id": "EV-PDB-8Q8Z-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.16}, "provenance": {"deposit_id": "8Q8Z", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q8Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA7 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-D of Microtubule-associated protein tau (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q8X", "evidence_id": "EV-PDB-8Q8X-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.54}, "provenance": {"deposit_id": "8Q8X", "doi": "10.1038/s41586-023-06788-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q8X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Tau - CTE-MIA5 (tau intermediate amyloid)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CL", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Microtubule-associated protein tau (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QNK", "evidence_id": "EV-PDB-9QNK-2", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "9QNK", "doi": "10.1039/d5dd00132c", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QNK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Tau pT245 phosphopeptide binding to 14-3-3sigma"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PVA", "evidence_id": "EV-PDB-9PVA-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9PVA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PVA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "295-330 S320F tau"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PGO", "evidence_id": "EV-PDB-9PGO-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.29}, "provenance": {"deposit_id": "9PGO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PGO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of brain-derived Tau fibril from Alzheimers disease patient tissue"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OFW", "evidence_id": "EV-PDB-9OFW-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9OFW", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OFW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "328-363 tau mutant S341L_S352I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform Tau-F of Microtubule-associated protein tau (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9O8H", "evidence_id": "EV-PDB-9O8H-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9O8H", "doi": "10.1016/j.isci.2026.115501", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9O8H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "amyloid fibril of recombinant full-length 2N4R tau complexed with mouse liver 18S ribosomal RNA"}
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{"conditions": {"applied_force_pn": null, "buffer": "100 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 12.2 nm.", "ph": 6.8, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDV46/", "evidence_id": "EV-SASBDB-SASDV46", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "radius_of_gyration", "uncertainty": 0.035, "unit": "nm", "value": 3.53}, "provenance": {"deposit_id": "SASDV46", "doi": "10.1073/pnas.2425831122", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDV46/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Conformational signatures induced by ubiquitin modification in the amyloid-forming tau repeat domain."}
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{"conditions": {"applied_force_pn": null, "buffer": "100 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Polyubiquitin-B"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 12.08 nm.", "ph": 6.8, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) with Polyubiquitin-B", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDV66/", "evidence_id": "EV-SASBDB-SASDV66", "mappings": [{"confidence": "medium", "justification": "Structure titled as bound to microtubules.", "rule": "tau-microtubule-title", "state_id": "tau-microtubule", "who": "rule:tau-microtubule-title"}], "molecule_id": "P10636", "observable": {"type": "radius_of_gyration", "uncertainty": 0.039, "unit": "nm", "value": 3.1}, "provenance": {"deposit_id": "SASDV66", "doi": "10.1073/pnas.2425831122", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDV66/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Conformational signatures induced by ubiquitin modification in the amyloid-forming tau repeat domain."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1-441 of isoform P10636-8; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/10805776", "evidence_id": "EV-DISPROT-DP01100r041", "mappings": [{"confidence": "medium", "justification": "DisProt region annotated as disorder.", "rule": "tau-disprot-disorder", "state_id": "tau-disordered", "who": "rule:tau-disprot-disorder"}], "molecule_id": "P10636", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 441}, "provenance": {"deposit_id": "DP01100r041", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01100"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP01100: disorder, residues 1-441"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1-441 of isoform P10636-8; evidence: small-angle X-ray scattering evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/18771286", "evidence_id": "EV-DISPROT-DP01100r042", "mappings": [{"confidence": "medium", "justification": "DisProt region annotated as disorder.", "rule": "tau-disprot-disorder", "state_id": "tau-disordered", "who": "rule:tau-disprot-disorder"}], "molecule_id": "P10636", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 441}, "provenance": {"deposit_id": "DP01100r042", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01100"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "saxs_sans", "title": "DisProt DP01100: disorder, residues 1-441"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1-352 of isoform P10636-2; evidence: small-angle X-ray scattering evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/18771286", "evidence_id": "EV-DISPROT-DP03552r001", "mappings": [{"confidence": "medium", "justification": "DisProt region annotated as disorder.", "rule": "tau-disprot-disorder", "state_id": "tau-disordered", "who": "rule:tau-disprot-disorder"}], "molecule_id": "P10636", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 352}, "provenance": {"deposit_id": "DP03552r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP03552"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "saxs_sans", "title": "DisProt DP03552: disorder, residues 1-352"}
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{"components": [], "domains": [{"end": 189, "name": "E1", "start": 28}, {"end": 341, "name": "BPTI/Kunitz inhibitor", "start": 291}, {"end": 565, "name": "E2", "start": 374}], "gene": "App", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P12023"}, "ligands": ["Cu(2+)", "Zn(2+)", "heparin"], "modifications": [{"kind": "ptm", "name": "Phosphoserine; by CK2", "position": 198, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by CK1", "position": 206, "source": "UniProtKB"}, {"kind": "ptm", "name": "Sulfotyrosine", "position": 217, "source": "UniProtKB"}, {"kind": "ptm", "name": "Sulfotyrosine", "position": 262, "source": "UniProtKB"}, {"kind": "ptm", "name": "Sulfotyrosine", "position": 336, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 441, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine", "position": 497, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine", "position": 729, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by APP-kinase I", "position": 730, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine; by CDK5 and MAPK10 and LRRK2", "position": 743, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine; by ABL1", "position": 757, "source": "UniProtKB"}], "molecule_id": "P12023", "molecule_type": "protein", "name": "Amyloid-beta precursor protein", "organism": {"name": "Mus musculus", "taxon_id": 10090}, "provenance": {"deposit_id": "P12023", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12023/entry"}, "record_type": "molecule", "sequence": "MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEEEADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQDPDKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN", "sequence_length": 770}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA repair protein XRCC4,Myosin-7 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WJ7", "evidence_id": "EV-PDB-5WJ7-1", "mappings": [], "molecule_id": "P12883", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "5WJ7", "doi": "10.1016/j.jsb.2017.07.006", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WJ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Amino Acids 1733-1797 of Human Beta Cardiac Myosin Fused to Xrcc4"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2YQF", "evidence_id": "EV-PDB-2YQF-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2YQF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2YQF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the death domain of Ankyrin-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2YVI", "evidence_id": "EV-PDB-2YVI-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.92}, "provenance": {"deposit_id": "2YVI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2YVI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a death domain of human ankryn protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ankyrin-1 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KBT", "evidence_id": "EV-PDB-3KBT-2", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "3KBT", "doi": "10.1182/blood-2009-11-255604", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KBT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in complex with the spectrin binding domain of human erythroid ankyrin (ZU5-ANK)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ankyrin-1 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KBU", "evidence_id": "EV-PDB-3KBU-2", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "3KBU", "doi": "10.1182/blood-2009-11-255604", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in complex with the spectrin binding domain of human erythroid ankyrin (ZU5-ANK), EMTS derivative"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EOH"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ankyrin-1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3UD1", "evidence_id": "EV-PDB-3UD1-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3UD1", "doi": "10.1016/j.jmb.2012.01.041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3UD1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of ZU5A-ZU5B domains of human erythrocyte ankyrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TW3", "evidence_id": "EV-PDB-7TW3-3", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "7TW3", "doi": "10.1038/s41594-022-00779-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TW3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZU", "evidence_id": "EV-PDB-7UZU-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7UZU", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ankyrin-1 (N-terminal region of membrane binding domain, local refinement from consensus reconstruction; bound to N-terminal peptide from band 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AJP", "CLR", "NAG", "PIO", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CS9", "evidence_id": "EV-PDB-8CS9-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.74}, "provenance": {"deposit_id": "8CS9", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CS9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Composite reconstruction of Class 1 of the erythrocyte ankyrin-1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CSL", "evidence_id": "EV-PDB-8CSL-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 25.0}, "provenance": {"deposit_id": "8CSL", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CSL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Sub-tomogram averaging of erythrocyte ankyrin-1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AJP", "CLR", "NAG", "PIO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CTE", "evidence_id": "EV-PDB-8CTE-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8CTE", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CTE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Class 2 of erythrocyte ankyrin-1 complex (Composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CSV", "evidence_id": "EV-PDB-8CSV-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8CSV", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CSV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of Anykyrin-1 (N-terminal half of membrane binding domain) in Class 2 of erythrocyte ankyrin-1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V0X", "evidence_id": "EV-PDB-7V0X-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7V0X", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of ankyrin-1 (C-terminal half), class 1 of erythrocyte ankyrin-1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AJP", "CLR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V0S", "evidence_id": "EV-PDB-7V0S-3", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7V0S", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V0S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of RhAG/CE trimer, class 1 of erythrocyte ankyrin-1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V0M", "evidence_id": "EV-PDB-7V0M-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7V0M", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V0M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of ankyrin-1 (N-terminal half), class 1 of erythrocyte ankyrin-1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AJP", "CLR", "NAG", "PIO", "PLC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V0K", "evidence_id": "EV-PDB-7V0K-3", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7V0K", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V0K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Consensus refinement of human erythrocyte ankyrin-1 complex (Composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AJP", "CLR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UZQ", "evidence_id": "EV-PDB-7UZQ-3", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.17}, "provenance": {"deposit_id": "7UZQ", "doi": "10.1038/s41594-022-00792-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UZQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of RhAG-RhCE-ANK1(AR1-5), from consensus refinement of all classes"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TW6", "evidence_id": "EV-PDB-7TW6-3", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.6}, "provenance": {"deposit_id": "7TW6", "doi": "10.1038/s41594-022-00779-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TW6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human ankyrin complex (B4P1A1) from red blood cell"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Ankyrin-1 (chains G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7TW5", "evidence_id": "EV-PDB-7TW5-3", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.7}, "provenance": {"deposit_id": "7TW5", "doi": "10.1038/s41594-022-00779-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7TW5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human ankyrin complex (B2P1A2) from red blood cell"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EOH", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ankyrin-1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3UD2", "evidence_id": "EV-PDB-3UD2-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.21}, "provenance": {"deposit_id": "3UD2", "doi": "10.1016/j.jmb.2012.01.041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3UD2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Selenomethionine ZU5A-ZU5B protein domains of human erythrocyte ankyrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Ankyrin-1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3F59", "evidence_id": "EV-PDB-3F59-1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3F59", "doi": "10.1182/blood-2008-10-184358", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3F59"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of ZU5-ANK, the spectrin binding region of human erythroid ankyrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=11390", "evidence_id": "EV-BMRB-11390", "mappings": [], "molecule_id": "P16157", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr11390", "doi": "10.13018/BMR11390", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=11390"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of the death domain of Ankyrin-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-1881", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P16157", "evidence_id": "EV-AFDB-AF-P16157-F1", "mappings": [], "molecule_id": "P16157", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 69.75}, "provenance": {"deposit_id": "AF-P16157-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P16157"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P16157-F1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Filamin A (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2AAV", "evidence_id": "EV-PDB-2AAV-1", "mappings": [], "molecule_id": "P21333", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2AAV", "doi": "10.1182/blood-2005-10-3964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2AAV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution NMR structure of Filamin A domain 17"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FILAMIN A (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2BP3", "evidence_id": "EV-PDB-2BP3-1", "mappings": [], "molecule_id": "P21333", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.32}, "provenance": {"deposit_id": "2BP3", "doi": "10.1182/BLOOD-2005-10-3964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2BP3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Filamin A domain 17 and GPIb alpha cytoplasmic domain complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Filamin-A (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LWX", "evidence_id": "EV-PDB-9LWX-1", "mappings": [], "molecule_id": "P21333", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.29}, "provenance": {"deposit_id": "9LWX", "doi": "10.1016/j.jmb.2025.169262", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LWX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Filamin A repeat 21"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Filamin-A/Integrin alpha-IIb light chain, form 2 chimera (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SC4", "evidence_id": "EV-PDB-7SC4-1", "mappings": [], "molecule_id": "P21333", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "7SC4", "doi": "10.1182/blood.2022018333", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "filamin complex-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Filamin-A (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ISW", "evidence_id": "EV-PDB-3ISW-1", "mappings": [], "molecule_id": "P21333", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "3ISW", "doi": "10.1074/jbc.M109.080911", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ISW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FILAMIN-A (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WFN", "evidence_id": "EV-PDB-2WFN-1", "mappings": [], "molecule_id": "P21333", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "2WFN", "doi": "10.1107/S0907444909037330", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WFN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Filamin A actin binding domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "Filamin-A (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2K7Q", "evidence_id": "EV-PDB-2K7Q-1", "mappings": [], "molecule_id": "P21333", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2K7Q", "doi": "10.1074/jbc.M109.019661", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2K7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Filamin A Ig-like domains 18-19"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30958", "evidence_id": "EV-BMRB-30958", "mappings": [], "molecule_id": "P21333", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30958", "doi": "10.13018/BMR30958", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30958"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Filamin complex-2"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris 50 mM NaCl 10mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.16 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Human Filamin A Ig-like domains 20-21/migfilin peptide complex", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDAE8/", "evidence_id": "EV-SASBDB-SASDAE8", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 2.41}, "provenance": {"deposit_id": "SASDAE8", "doi": "10.1371/journal.pone.0136969", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDAE8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris 50 mM NaCl 10mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.5 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Human Filamin A Ig-like domains 20-21", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDAF8/", "evidence_id": "EV-SASBDB-SASDAF8", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 2.43}, "provenance": {"deposit_id": "SASDAF8", "doi": "10.1371/journal.pone.0136969", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDAF8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris 50 mM NaCl 10mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.2 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Human Filamin A Ig-like domains 20-21*/migfilin peptide complex", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDAG8/", "evidence_id": "EV-SASBDB-SASDAG8", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 2.35}, "provenance": {"deposit_id": "SASDAG8", "doi": "10.1371/journal.pone.0136969", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDAG8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris 50 mM NaCl 10mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.8 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Human Filamin A Ig-like domains 20-21*", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDAH8/", "evidence_id": "EV-SASBDB-SASDAH8", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 1.9}, "provenance": {"deposit_id": "SASDAH8", "doi": "10.1371/journal.pone.0136969", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDAH8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris 50 mM NaCl 10 mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.2 nm.", "ph": null, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Human Filamin A Ig-like domains 16-17", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDB32/", "evidence_id": "EV-SASBDB-SASDB32", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 1.83}, "provenance": {"deposit_id": "SASDB32", "doi": "10.1038/s41598-017-04441-x", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDB32/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Skeletal Dysplasia Mutations Effect on Human Filamins' Structure and Mechanosensing."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris 50 mM NaCl 10 mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 8.3 nm.", "ph": null, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Human Filamin A Ig-like domains 16-17*", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDB42/", "evidence_id": "EV-SASBDB-SASDB42", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": null, "unit": "nm", "value": 2.4}, "provenance": {"deposit_id": "SASDB42", "doi": "10.1038/s41598-017-04441-x", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDB42/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Skeletal Dysplasia Mutations Effect on Human Filamins' Structure and Mechanosensing."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 100 mM NaCl, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 7.4 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Filamin A Ig.like domains 3-5 P637Q mutant", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDEP7/", "evidence_id": "EV-SASBDB-SASDEP7", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": 0.1, "unit": "nm", "value": 2.21}, "provenance": {"deposit_id": "SASDEP7", "doi": "10.1016/j.str.2018.09.007", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDEP7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 100 mM NaCl, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 7.34 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Filamin A Ig-like domains 3-5", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDEQ7/", "evidence_id": "EV-SASBDB-SASDEQ7", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": 0.1, "unit": "nm", "value": 2.19}, "provenance": {"deposit_id": "SASDEQ7", "doi": "10.1016/j.str.2018.09.007", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDEQ7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 100 mM NaCl, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.5 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Filamin A Ig-like domains 4-6", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDFD3/", "evidence_id": "EV-SASBDB-SASDFD3", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": 0.03, "unit": "nm", "value": 2.73}, "provenance": {"deposit_id": "SASDFD3", "doi": "10.1016/j.bpj.2019.08.032", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDFD3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia."}
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{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 100 mM NaCl, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Filamin A Ig-like domains 4-6, H743P mutation", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDFG3/", "evidence_id": "EV-SASBDB-SASDFG3", "mappings": [], "molecule_id": "P21333", "observable": {"type": "radius_of_gyration", "uncertainty": 0.1, "unit": "nm", "value": 4.29}, "provenance": {"deposit_id": "SASDFG3", "doi": "10.1016/j.bpj.2019.08.032", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDFG3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Synaptotagmin-1 (chains A,F)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KI6", "evidence_id": "EV-PDB-2KI6-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KI6", "doi": "10.1074/jbc.M109.066357", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KI6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Synaptotagmin-1 (chains E)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N1T", "evidence_id": "EV-PDB-2N1T-5", "mappings": [], "molecule_id": "P21579", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N1T", "doi": "10.1038/nsmb.3035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N1T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "SYNAPTOTAGMIN-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4V11", "evidence_id": "EV-PDB-4V11-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "4V11", "doi": "10.1523/JNEUROSCI.4248-14.2015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4V11"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6TZ3", "evidence_id": "EV-PDB-6TZ3-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.17}, "provenance": {"deposit_id": "6TZ3", "doi": "10.1016/j.neuron.2020.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6TZ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6U41", "evidence_id": "EV-PDB-6U41-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "6U41", "doi": "10.1016/j.neuron.2020.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6U41"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6U4W", "evidence_id": "EV-PDB-6U4W-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "6U4W", "doi": "10.1016/j.neuron.2020.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6U4W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.4 A structure of a pathogenic human Syt 1 C2B (D366E)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains I,J,K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8B8I", "evidence_id": "EV-PDB-8B8I-2", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "8B8I", "doi": "10.1186/s12951-026-04489-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8B8I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nanobody (NbLumSyt1) bound to human Syt1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7U4Q", "evidence_id": "EV-PDB-7U4Q-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.56}, "provenance": {"deposit_id": "7U4Q", "doi": "10.1016/j.bpj.2024.11.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7U4Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Synaptotagmin-1 C2A Y181F Ca2+ bound"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains BBB)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ZVN", "evidence_id": "EV-PDB-6ZVN-2", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6ZVN", "doi": "10.3390/toxins12090603", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ZVN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Botulinum neurotoxin B2 binding domain in complex with human synaptotagmin I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6U4U", "evidence_id": "EV-PDB-6U4U-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.3}, "provenance": {"deposit_id": "6U4U", "doi": "10.1016/j.neuron.2020.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6U4U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "1.3 A structure of a pathogenic human Syt 1 C2B (I368T)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains 33,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6G5K", "evidence_id": "EV-PDB-6G5K-2", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "6G5K", "doi": "10.1126/sciadv.aau7196", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6G5K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the binding domain of Botulinum Neurotoxin type B in complex with human synaptotagmin 1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4ISQ", "evidence_id": "EV-PDB-4ISQ-2", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "4ISQ", "doi": "10.1016/j.str.2013.06.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4ISQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Binding domain of Botulinum neurotoxin DC in complex with human synaptotagmin I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3F04", "evidence_id": "EV-PDB-3F04-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "3F04", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3F04"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Synaptotagmin I C2A domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CU", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3F00", "evidence_id": "EV-PDB-3F00-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.36}, "provenance": {"deposit_id": "3F00", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3F00"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Synaptotagmin I C2A domain with Cu(II)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Synaptotagmin-1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2R83", "evidence_id": "EV-PDB-2R83-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "2R83", "doi": "10.1021/bi701651k", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2R83"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure analysis of human synaptotagmin 1 C2A-C2B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Putative uncharacterized protein (chains A,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2K8M", "evidence_id": "EV-PDB-2K8M-1", "mappings": [], "molecule_id": "P21579", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2K8M", "doi": "10.1016/j.bbrc.2009.01.143", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2K8M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "S100A13-C2A binary complex structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=15785", "evidence_id": "EV-BMRB-15785", "mappings": [], "molecule_id": "P21579", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr15785", "doi": "10.13018/BMR15785", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=15785"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "C2A domain of synaptototagmin I solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 81-142; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/27191789", "evidence_id": "EV-DISPROT-DP04145r004", "mappings": [], "molecule_id": "P21579", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 62}, "provenance": {"deposit_id": "DP04145r004", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP04145"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP04145: disorder, residues 81-142"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Talin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZW4", "evidence_id": "EV-PDB-7ZW4-1", "mappings": [], "molecule_id": "P26039", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "7ZW4", "doi": "10.1242/jcs.262116", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZW4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Talin R7R8 domains with Caskin-2 LD-peptide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Integrin beta-3,Talin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VGU", "evidence_id": "EV-PDB-6VGU-1", "mappings": [], "molecule_id": "P26039", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "6VGU", "doi": "10.1073/pnas.2014583117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VGU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Talin-1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5IC1", "evidence_id": "EV-PDB-5IC1-1", "mappings": [], "molecule_id": "P26039", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "5IC1", "doi": "10.1016/j.str.2016.02.020", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5IC1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural analysis of a talin triple domain module, E1794Y, E1797Y, Q1801Y mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1XS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LW1", "evidence_id": "EV-PDB-4LW1-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.631}, "provenance": {"deposit_id": "4LW1", "doi": "10.1021/jm401333u", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LW1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit (chains N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PD4", "evidence_id": "EV-PDB-9PD4-11", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9PD4", "doi": "10.1038/s41586-026-10122-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PD4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "NER dual incision complex - DuIM"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "SF4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit, N-terminally processed (chains L)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A89", "evidence_id": "EV-PDB-9A89-12", "mappings": [], "molecule_id": "P27694", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A89", "doi": "10.1038/s41467-024-52860-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A89"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Structure of the pre-incision complex in nucleotide excision repair with tilted XPG core"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Subunit A (chains A)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A04", "evidence_id": "EV-PDB-9A04-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A04", "doi": "10.1093/nar/gkz1231", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A04"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Integrative model of 5' Nucleotide excision repair complex of XPA-DBD and RPA70AB"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8K00", "evidence_id": "EV-PDB-8K00-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "8K00", "doi": "10.7554/eLife.81639", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8K00"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RPA70N-MRE11 fusion"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3HZ"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4R4Q", "evidence_id": "EV-PDB-4R4Q-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "4R4Q", "doi": "10.1021/ml5003629", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4R4Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of RPA70N in complex with 5-(3-((N-(4-(5-carboxyfuran-2-yl)benzyl)acetamido)methyl)phenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NB3", "evidence_id": "EV-PDB-4NB3-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "4NB3", "doi": "10.1021/jm401730y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NB3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of RPA70N in complex with a 3,4 dichlorophenylalanine ATRIP derived peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1XT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4LUZ", "evidence_id": "EV-PDB-4LUZ-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "4LUZ", "doi": "10.1021/jm401333u", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4LUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2B29", "evidence_id": "EV-PDB-2B29-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "2B29", "doi": "10.1073/pnas.0504614102", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2B29"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "N-terminal domain of the RPA70 subunit of human replication protein A."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FGU", "evidence_id": "EV-PDB-1FGU-1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1FGU", "doi": "10.1093/emboj/20.3.612", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FGU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SSDNA-BINDING DOMAIN OF THE LARGE SUBUNIT OF REPLICATION PROTEIN A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5822", "evidence_id": "EV-BMRB-5822", "mappings": [], "molecule_id": "P27694", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5822", "doi": "10.13018/BMR5822", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5822"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H, 15N and 13C assignments of single-stranded DNA binding domains from the 70 kDa subunit of Human Replication Protein A"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 150 mM NaCl, 2% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: 3-prime  Nucleotide Excision Repair Junction Model Substrate", "partner: DNA repair protein complementing XP-A cells"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.7 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit with DNA repair protein complementing XP-A cells, 3-prime  Nucleotide Excision Repair Junction Model Substrate", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDH44/", "evidence_id": "EV-SASBDB-SASDH44", "mappings": [], "molecule_id": "P27694", "observable": {"type": "radius_of_gyration", "uncertainty": 0.05, "unit": "nm", "value": 3.138}, "provenance": {"deposit_id": "SASDH44", "doi": "10.1093/nar/gkz1231", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDH44/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "A key interaction with RPA orients XPA in NER complexes."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 150 mM NaCl, 2% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: 5-prime Nucleotide Excision Repair Junction Model Substrate", "partner: DNA repair protein complementing XP-A cells"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 97 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit with DNA repair protein complementing XP-A cells, 5-prime Nucleotide Excision Repair Junction Model Substrate", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDH54/", "evidence_id": "EV-SASBDB-SASDH54", "mappings": [], "molecule_id": "P27694", "observable": {"type": "radius_of_gyration", "uncertainty": 0.01, "unit": "nm", "value": 2.947}, "provenance": {"deposit_id": "SASDH54", "doi": "10.1093/nar/gkz1231", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDH54/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "A key interaction with RPA orients XPA in NER complexes."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris pH 8.0, 150 mM NaCl, 2% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: 5-prime ss-ds DNA junction NER model substrate", "partner: DNA repair protein complementing XP-A cells", "partner: Replication protein A 14 kDa subunit", "partner: Replication protein A 32 kDa subunit"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16.45 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit with Replication protein A 14 kDa subunit, DNA repair protein complementing XP-A cells, Replication protein A 32 kDa subunit, 5-prime ss-ds DNA junction NER model substrate", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDP24/", "evidence_id": "EV-SASBDB-SASDP24", "mappings": [], "molecule_id": "P27694", "observable": {"type": "radius_of_gyration", "uncertainty": 0.932, "unit": "nm", "value": 4.626}, "provenance": {"deposit_id": "SASDP24", "doi": "10.1073/pnas.2207408119", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDP24/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris pH 8.0, 150 mM NaCl, 2% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: 3-prime ss-ds DNA junction NER model substrate", "partner: DNA repair protein complementing XP-A cells", "partner: Replication protein A 14 kDa subunit", "partner: Replication protein A 32 kDa subunit"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 14.65 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Replication protein A 70 kDa DNA-binding subunit with DNA repair protein complementing XP-A cells, Replication protein A 32 kDa subunit, Replication protein A 14 kDa subunit, 3-prime ss-ds DNA junction NER model substrate", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDPZ3/", "evidence_id": "EV-SASBDB-SASDPZ3", "mappings": [], "molecule_id": "P27694", "observable": {"type": "radius_of_gyration", "uncertainty": 0.512, "unit": "nm", "value": 4.286}, "provenance": {"deposit_id": "SASDPZ3", "doi": "10.1073/pnas.2207408119", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDPZ3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 109-168; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/10526407", "evidence_id": "EV-DISPROT-DP00061r005", "mappings": [], "molecule_id": "P27694", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 60}, "provenance": {"deposit_id": "DP00061r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP00061"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP00061: disorder, residues 109-168"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 105-180; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/17721672", "evidence_id": "EV-DISPROT-DP00061r007", "mappings": [], "molecule_id": "P27694", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 76}, "provenance": {"deposit_id": "DP00061r007", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP00061"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP00061: disorder, residues 105-180"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-616", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P27694", "evidence_id": "EV-AFDB-AF-P27694-F1", "mappings": [], "molecule_id": "P27694", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 83.81}, "provenance": {"deposit_id": "AF-P27694-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P27694"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P27694-F1"}
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"doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35579/entry"}, "record_type": "molecule", "sequence": "MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE", "sequence_length": 1960}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 1 of Myosin-9 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SZR", "evidence_id": "EV-PDB-9SZR-1", "mappings": [], "molecule_id": "P35579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.3}, "provenance": {"deposit_id": "9SZR", "doi": "10.1126/sciadv.aed1858", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SZR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "shutdown state non-muscle myosin 2A heads region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "MG", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 1 of Myosin-9 (chains A,B,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SYU", "evidence_id": "EV-PDB-9SYU-1", "mappings": [], "molecule_id": "P35579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9SYU", "doi": "10.1126/sciadv.aed1858", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SYU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "shutdown state non-muscle myosin 2A heads region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myosin-9,Alpha-actinin A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IHL", "evidence_id": "EV-PDB-9IHL-1", "mappings": [], "molecule_id": "P35579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.02}, "provenance": {"deposit_id": "9IHL", "doi": "10.1016/j.jbc.2025.110691", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IHL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the Human Nonmuscle Myosin 2A Motor Domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Myosin-9 (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4ETO", "evidence_id": "EV-PDB-4ETO-2", "mappings": [], "molecule_id": "P35579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.54}, "provenance": {"deposit_id": "4ETO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4ETO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of S100A4 in complex with non-muscle myosin-IIA peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOSIN-9 (chains Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4CFR", "evidence_id": "EV-PDB-4CFR-2", "mappings": [], "molecule_id": "P35579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "4CFR", "doi": "10.1371/JOURNAL.PONE.0097654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4CFR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ca-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with non- muscle myosin IIA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOSIN-9 (chains Q,R)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4CFQ", "evidence_id": "EV-PDB-4CFQ-2", "mappings": [], "molecule_id": "P35579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.37}, "provenance": {"deposit_id": "4CFQ", "doi": "10.1371/JOURNAL.PONE.0097654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4CFQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ca-bound truncated (delta13C) and C3S, C81S and C86S mutated S100A4 complexed with non-muscle myosin IIA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "AZI", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MYOSIN-9 (chains Q)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ZWH", "evidence_id": "EV-PDB-3ZWH-2", "mappings": [], "molecule_id": "P35579", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.94}, "provenance": {"deposit_id": "3ZWH", "doi": "10.1073/PNAS.1114732109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ZWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ca2+-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with myosin IIA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.1, "salt_mM": null, "temperature_c": 39.85}, "construct": {"description": "Myosin heavy chain, non-muscle IIa (chains C)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LNK", "evidence_id": "EV-PDB-2LNK-1", "mappings": [], "molecule_id": "P35579", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LNK", "doi": "10.1016/j.str.2012.02.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LNK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.1, "salt_mM": null, "temperature_c": 39.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=18169", "evidence_id": "EV-BMRB-18169", "mappings": [], "molecule_id": "P35579", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr18169", "doi": "10.13018/BMR18169", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=18169"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.0, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25208", "evidence_id": "EV-BMRB-25208", "mappings": [], "molecule_id": "P35579", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25208", "doi": "10.13018/BMR25208", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25208"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone and Side Chain Chemical Shift Assignments for S100A4dC in complex with MPT"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.2, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25992", "evidence_id": "EV-BMRB-25992", "mappings": [], "molecule_id": "P35579", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25992", "doi": "10.13018/BMR25992", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25992"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone and Side Chain Chemical Shift Assignments for the myosin IIA fragment 1893-1937 (MPT)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-1960", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P35579", "evidence_id": "EV-AFDB-AF-P35579-F1", "mappings": [], "molecule_id": "P35579", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 76.19}, "provenance": {"deposit_id": "AF-P35579-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P35579"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P35579-F1"}
{"components": [], "domains": [], "gene": "SNCA", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P37840"}, "ligands": ["Cu cation"], "modifications": [{"kind": "ptm", "name": "N-acetylmethionine", "position": 1, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 87, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine; by FYN", "position": 125, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by GRK2, PLK2, CK2, CK1 and GRK5", "position": 129, "source": "UniProtKB"}], "molecule_id": "P37840", "molecule_type": "protein", "name": "Alpha-synuclein", "organism": {"name": "Homo sapiens", "taxon_id": 9606}, "provenance": {"deposit_id": "P37840", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37840/entry"}, "record_type": "molecule", "sequence": "MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA", "sequence_length": 140}
{"assumptions": ["No observed structure of the free monomer exists; the state is defined by the absence of a folded model.", "Ensemble descriptions from PED, NMR, SAXS and smFRET are not yet ingested. No model is exported.", "Assumes unbound, monomeric protein under the conditions of the source experiments."], "basis": "inferred", "description": "Intrinsically disordered monomer. No observed structure; ensemble descriptions are not yet ingested.", "family_label": null, "molecule_id": "P37840", "name": "disordered monomer", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P37840.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P37840.yaml"}, "record_type": "state", "representative_model": null, "secondary_structure": null, "state_id": "aS-disordered", "status": "draft"}
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{"assumptions": [], "basis": "observed", "description": "Cross-beta fibril, as in 6A6B. Polymorph differences are not separated in the pilot.", "family_label": null, "molecule_id": "P37840", "name": "fibril", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P37840.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P37840.yaml"}, "record_type": "state", "representative_model": "aS-fibril-cif", "secondary_structure": null, "state_id": "aS-fibril", "status": "draft"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6OSM", "evidence_id": "EV-PDB-6OSM-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6OSM", "doi": "10.1016/j.jmb.2019.07.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6OSM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the N-terminally acetylated C-terminal Alpha-synuclein truncation Ac1-103"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XYO", "evidence_id": "EV-PDB-6XYO-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "6XYO", "doi": "10.1038/s41586-020-2317-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Multiple system atrophy Type I alpha-synuclein filament"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6UFR", "evidence_id": "EV-PDB-6UFR-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6UFR", "doi": "10.1073/pnas.1917914117", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6UFR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of recombinantly assembled E46K alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SSX", "evidence_id": "EV-PDB-6SSX-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "6SSX", "doi": "10.7554/eLife.48907", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SSX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-em structure of alpha-synuclein fibril polymorph 2A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SST", "evidence_id": "EV-PDB-6SST-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6SST", "doi": "10.7554/eLife.48907", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SST"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-em structure of alpha-synuclein fibril polymorph 2B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6RTB", "evidence_id": "EV-PDB-6RTB-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "6RTB", "doi": "10.7554/eLife.48907", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6RTB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-em structure of alpha-synuclein fibril polymorph 2B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6RT0", "evidence_id": "EV-PDB-6RT0-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "6RT0", "doi": "10.7554/eLife.48907", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6RT0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "cryo-em structure of alpha-synuclein fibril polymorph 2A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,V,W,X,Y,Z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PES", "evidence_id": "EV-PDB-6PES-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "6PES", "doi": "10.1038/s41594-019-0322-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein H50Q Wide Fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PEO", "evidence_id": "EV-PDB-6PEO-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6PEO", "doi": "10.1038/s41594-019-0322-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PEO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein H50Q Narrow Fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6OSL", "evidence_id": "EV-PDB-6OSL-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "6OSL", "doi": "10.1016/j.jmb.2019.07.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6OSL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the N-terminally acetylated C-terminal Alpha-synuclein truncation Ac1-122"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6OSJ", "evidence_id": "EV-PDB-6OSJ-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "6OSJ", "doi": "10.1016/j.jmb.2019.07.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6OSJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the N-terminally acetylated full length alpha-synuclein fibrils (Ac1-140)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptide from Alpha-synuclein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5CRW", "evidence_id": "EV-PDB-5CRW-2", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "5CRW", "doi": "10.1038/srep13909", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5CRW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the b'-a' domain of oxidized protein disulfide isomerase complexed with alpha-synuclein peptide (31-41)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4RIL", "evidence_id": "EV-PDB-4RIL-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.43}, "provenance": {"deposit_id": "4RIL", "doi": "10.1038/nature15368", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4RIL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4RIK", "evidence_id": "EV-PDB-4RIK-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.854}, "provenance": {"deposit_id": "4RIK", "doi": "10.1038/nature15368", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4RIK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q28", "evidence_id": "EV-PDB-3Q28-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3Q28", "doi": "10.1002/pro.630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q28"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyrstal structure of human alpha-synuclein (58-79) fused to maltose binding protein (MBP)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein/alpha-synuclein chimeric protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3Q25", "evidence_id": "EV-PDB-3Q25-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "3Q25", "doi": "10.1002/pro.630", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3Q25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/36QD", "evidence_id": "EV-PDB-36QD-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "36QD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/36QD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM of rPFFs (recombinant preformed fibrils)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 7.85}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/34AH", "evidence_id": "EV-PDB-34AH-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "34AH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/34AH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Cu(II) - alpha-synuclein monomer complex - local structure of binding site His50 with Glu46 as ligand"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -100.15}, "construct": {"description": "ALPHA-SYNUCLEIN PEPTIDE (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2X6M", "evidence_id": "EV-PDB-2X6M-2", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.62}, "provenance": {"deposit_id": "2X6M", "doi": "10.1016/J.JMB.2010.07.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2X6M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N0A", "evidence_id": "EV-PDB-2N0A-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N0A", "doi": "10.1038/nsmb.3194", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N0A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Atomic-resolution structure of alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.36, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "Alpha-synuclein (chains B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M55", "evidence_id": "EV-PDB-2M55-2", "mappings": [], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M55", "doi": "10.1021/bi400199p", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M55"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of the complex of an N-terminally acetylated alpha-synuclein peptide with calmodulin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2JN5", "evidence_id": "EV-PDB-2JN5-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2JN5", "doi": "10.1096/fj.09-133082", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2JN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution Structure of a Dodecapeptide from Alpha-Synuclein Bound with Synphilin-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": 25.05}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1XQ8", "evidence_id": "EV-PDB-1XQ8-1", "mappings": [{"confidence": "medium", "justification": "NMR structure of the micelle-bound helical form; membrane-mimetic conditions, so confidence is medium.", "rule": "curator_assignment", "state_id": "aS-micelle-helix", "who": "curator:draft (unreviewed)"}], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1XQ8", "doi": "10.1074/jbc.M411805200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1XQ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Human micelle-bound alpha-synuclein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/12AT", "evidence_id": "EV-PDB-12AT-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "12AT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/12AT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments (doublet) from M83(+/+) mouse brains with A53T mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/12AR", "evidence_id": "EV-PDB-12AR-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "12AR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/12AR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments (singlet) from M83(+/+) mouse brains with A53T mutation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/12AQ", "evidence_id": "EV-PDB-12AQ-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "12AQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/12AQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments (doublet) from Parkinson's disease with A53T mutation in SNCA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/12AP", "evidence_id": "EV-PDB-12AP-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "12AP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/12AP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments (singlet) from Parkinson's disease with A53T mutation in SNCA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,U,W,X,Y,Z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/10XU", "evidence_id": "EV-PDB-10XU-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "10XU", "doi": "10.1038/s41467-025-66146-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/10XU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of amplified aSyn filament by using seed amplification assay (SAA) from MSA patient CSF."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7C1D", "evidence_id": "EV-PDB-7C1D-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7C1D", "doi": "10.1073/pnas.2012435118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7C1D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the hE46K cross-seeded hWT alpha-synuclein fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L7H", "evidence_id": "EV-PDB-7L7H-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7L7H", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L7H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NCG", "evidence_id": "EV-PDB-7NCG-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "7NCG", "doi": "10.1002/2211-5463.13110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NCG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 2A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NCH", "evidence_id": "EV-PDB-7NCH-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "7NCH", "doi": "10.1002/2211-5463.13110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NCH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 1B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NCJ", "evidence_id": "EV-PDB-7NCJ-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.23}, "provenance": {"deposit_id": "7NCJ", "doi": "10.1002/2211-5463.13110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NCJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 2AB alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NCK", "evidence_id": "EV-PDB-7NCK-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "7NCK", "doi": "10.1002/2211-5463.13110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NCK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 3 alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OZG", "evidence_id": "EV-PDB-7OZG-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7OZG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OZG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PMCA-amplified alpha-synuclein fibril polymorph, Parkinson's Disease patient-derived seeds"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OZH", "evidence_id": "EV-PDB-7OZH-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "7OZH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OZH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PMCA-amplified alpha-synuclein fibril polymorph, Multiple System Atrophy patient-derived seeds"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UAK", "evidence_id": "EV-PDB-7UAK-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "7UAK", "doi": "10.1016/j.jbc.2023.104566", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UAK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of recombinantly assembled A53E alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V49", "evidence_id": "EV-PDB-7V49-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7V49", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V49"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V4A", "evidence_id": "EV-PDB-7V4A-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7V4A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V4A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Heparin-induced alpha-synuclein fibrils polymorph 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V4B", "evidence_id": "EV-PDB-7V4B-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7V4B", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V4B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Heparin-induced alpha-synuclein fibrils polymorph 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V4C", "evidence_id": "EV-PDB-7V4C-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7V4C", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V4C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Heparin-induced alpha-synuclein fibrils polymorph 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V4D", "evidence_id": "EV-PDB-7V4D-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7V4D", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V4D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Heparin-remodelled alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WNZ", "evidence_id": "EV-PDB-7WNZ-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7WNZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WNZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of human alpha-synuclein A53T fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,O,P,Q,R,S,T,U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WO0", "evidence_id": "EV-PDB-7WO0-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7WO0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WO0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XJX", "evidence_id": "EV-PDB-7XJX-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7XJX", "doi": "10.1016/j.jmb.2022.167680", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XJX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Fe3+ induced alpha-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XO0", "evidence_id": "EV-PDB-7XO0-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7XO0", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XO0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XO1", "evidence_id": "EV-PDB-7XO1-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7XO1", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XO1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XO2", "evidence_id": "EV-PDB-7XO2-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7XO2", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XO2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XO3", "evidence_id": "EV-PDB-7XO3-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7XO3", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XO3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YK8", "evidence_id": "EV-PDB-7YK8-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7YK8", "doi": "10.1021/jacs.2c10854", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YK8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of dLAG3-alpha-syn fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["V79"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNF", "evidence_id": "EV-PDB-7YNF-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7YNF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CCA-bound alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNG", "evidence_id": "EV-PDB-7YNG-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7YNG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CR-bound alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IZ8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNL", "evidence_id": "EV-PDB-7YNL-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7YNL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EB-bound alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TFX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNM", "evidence_id": "EV-PDB-7YNM-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7YNM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ThT-bound alpha-synuclein fibrils conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TFX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNN", "evidence_id": "EV-PDB-7YNN-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7YNN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ThT-bound alpha-synuclein fibrils conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IZV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNO", "evidence_id": "EV-PDB-7YNO-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7YNO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PiB-bound alpha-synuclein fibrils conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IZM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNP", "evidence_id": "EV-PDB-7YNP-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7YNP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BF227-bound alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNR", "evidence_id": "EV-PDB-7YNR-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7YNR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "C05-03-bound alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNS", "evidence_id": "EV-PDB-7YNS-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7YNS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SIL5-bound alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNT", "evidence_id": "EV-PDB-7YNT-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7YNT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "pFTAA-bound alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8A4L", "evidence_id": "EV-PDB-8A4L-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "8A4L", "doi": "10.1038/s41467-022-34552-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8A4L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Lipidic alpha-synuclein fibril - polymorph L2A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8A9L", "evidence_id": "EV-PDB-8A9L-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8A9L", "doi": "10.1038/s41586-022-05319-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8A9L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ADS", "evidence_id": "EV-PDB-8ADS-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "8ADS", "doi": "10.1038/s41467-022-34552-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ADS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Lipidic alpha-synuclein fibril - polymorph L2B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ADU", "evidence_id": "EV-PDB-8ADU-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "8ADU", "doi": "10.1038/s41467-022-34552-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ADU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Lipidic alpha-synuclein fibril - polymorph L1A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ADV", "evidence_id": "EV-PDB-8ADV-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "8ADV", "doi": "10.1038/s41467-022-34552-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ADV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Lipidic alpha-synuclein fibril - polymorph L1B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Alpha-synuclein 110-120 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8B9V", "evidence_id": "EV-PDB-8B9V-3", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.16}, "provenance": {"deposit_id": "8B9V", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8B9V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Lu AF82422 in complex with alpha-synuclein 110-120"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AEX", "evidence_id": "EV-PDB-8AEX-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "8AEX", "doi": "10.1038/s41467-022-34552-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AEX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Lipidic alpha-synuclein fibril - polymorph L3A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ADW", "evidence_id": "EV-PDB-8ADW-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "8ADW", "doi": "10.1038/s41467-022-34552-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ADW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Lipidic alpha-synuclein fibril - polymorph L1C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IZV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YNQ", "evidence_id": "EV-PDB-7YNQ-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7YNQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YNQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PiB-bound alpha-synuclein fibrils conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YK2", "evidence_id": "EV-PDB-7YK2-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7YK2", "doi": "10.1021/jacs.2c10854", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YK2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Apo-alpha-syn fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1KI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WMM", "evidence_id": "EV-PDB-7WMM-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7WMM", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WMM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "alpha-synuclein fibril-F0502B complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V48", "evidence_id": "EV-PDB-7V48-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7V48", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V48"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V47", "evidence_id": "EV-PDB-7V47-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7V47", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V47"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["COA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7STX", "evidence_id": "EV-PDB-7STX-3", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7STX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7STX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human NatB in complex with CoA-Alpha-Synuclein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NCI", "evidence_id": "EV-PDB-7NCI-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "7NCI", "doi": "10.1002/2211-5463.13110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NCI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 2B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NCA", "evidence_id": "EV-PDB-7NCA-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "7NCA", "doi": "10.1002/2211-5463.13110", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NCA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type 1A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LC9", "evidence_id": "EV-PDB-7LC9-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7LC9", "doi": "10.1073/pnas.2023487118", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LC9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the N-terminal alpha-synuclein truncation 41-140"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7E0F", "evidence_id": "EV-PDB-7E0F-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "7E0F", "doi": "10.1038/s41467-021-26433-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7E0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of G51D alpha-synuclein amyloid fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CE7", "evidence_id": "EV-PDB-8CE7-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8CE7", "doi": "10.1007/s00401-023-02550-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y2P", "evidence_id": "EV-PDB-8Y2P-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8Y2P", "doi": "10.1016/j.jbc.2024.107862", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y2P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of a-synuclein fibril in Tris buffer."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["KDH"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XWD", "evidence_id": "EV-PDB-8XWD-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8XWD", "doi": "10.1002/advs.202416721", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XWD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Croy-EM structure of alpha synuclein fibril with EGCG"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["Y9W"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7R", "evidence_id": "EV-PDB-8X7R-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8X7R", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "C05-03-bound E46K alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3LS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7Q", "evidence_id": "EV-PDB-8X7Q-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8X7Q", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "pFTAA-bound E46K alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["V79"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7P", "evidence_id": "EV-PDB-8X7P-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8X7P", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CCA-bound E46K alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IZV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7O", "evidence_id": "EV-PDB-8X7O-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8X7O", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "PiB-bound E46K mutanted alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["59P"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7M", "evidence_id": "EV-PDB-8X7M-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8X7M", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CR-bound E46K alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["IZ8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7L", "evidence_id": "EV-PDB-8X7L-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8X7L", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "EB-bound E46K alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TFX"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8X7B", "evidence_id": "EV-PDB-8X7B-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8X7B", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8X7B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ThT-bound E46K alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RRR", "evidence_id": "EV-PDB-8RRR-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8RRR", "doi": "10.1038/s42003-025-07906-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RRR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein amyloid fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RQM", "evidence_id": "EV-PDB-8RQM-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8RQM", "doi": "10.1038/s42003-025-07906-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RQM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein amyloid fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RI9", "evidence_id": "EV-PDB-8RI9-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8RI9", "doi": "10.1021/jacs.3c14703", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RI9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Late alpha-Synuclein fibril structure from liquid-liquid phase separations."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QPZ", "evidence_id": "EV-PDB-8QPZ-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8QPZ", "doi": "10.1073/pnas.2315006121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QPZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of recombinant DeltaN7 alpha-synuclein in PBS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PK4", "evidence_id": "EV-PDB-8PK4-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8PK4", "doi": "10.7554/eLife.93562", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PK4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of the type 5A polymorph of alpha-synuclein."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PK2", "evidence_id": "EV-PDB-8PK2-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "8PK2", "doi": "10.7554/eLife.93562", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PK2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of the type 1m polymorph of alpha-synuclein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PJO", "evidence_id": "EV-PDB-8PJO-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.31}, "provenance": {"deposit_id": "8PJO", "doi": "10.7554/eLife.93562", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PJO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of the type 3D polymorph of alpha-synuclein E46K mutant at low pH."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PIX", "evidence_id": "EV-PDB-8PIX-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.41}, "provenance": {"deposit_id": "8PIX", "doi": "10.7554/eLife.93562", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PIX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo EM structure of the type 3C polymorph of alpha-synuclein at low pH."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HZB", "evidence_id": "EV-PDB-8HZB-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8HZB", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HZB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Formed alpha-synuclein fibrils after incubation with heparin for 1 hour (Hep-remod-1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H05", "evidence_id": "EV-PDB-8H05-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8H05", "doi": "10.1016/j.str.2022.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H05"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CMC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G0L", "evidence_id": "EV-PDB-8G0L-3", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "8G0L", "doi": "10.1021/jacs.3c03887", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G0L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.6, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FPT", "evidence_id": "EV-PDB-8FPT-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8FPT", "doi": "10.1038/s41467-024-46832-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FPT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,I,J,K,L,M,N,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CZ6", "evidence_id": "EV-PDB-8CZ6-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8CZ6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CZ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CZ3", "evidence_id": "EV-PDB-8CZ3-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8CZ3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CZ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case X"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CZ2", "evidence_id": "EV-PDB-8CZ2-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8CZ2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CZ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CZ1", "evidence_id": "EV-PDB-8CZ1-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8CZ1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CZ1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CZ0", "evidence_id": "EV-PDB-8CZ0-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8CZ0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CZ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYY", "evidence_id": "EV-PDB-8CYY-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8CYY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,I,J,K,L,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYX", "evidence_id": "EV-PDB-8CYX-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8CYX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYW", "evidence_id": "EV-PDB-8CYW-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8CYW", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYV", "evidence_id": "EV-PDB-8CYV-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8CYV", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,I,J,K,L,M,N,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYT", "evidence_id": "EV-PDB-8CYT-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8CYT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,I,J,K,L,M,N,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYS", "evidence_id": "EV-PDB-8CYS-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8CYS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CYR", "evidence_id": "EV-PDB-8CYR-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "8CYR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CYR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein fibril from spontaneous control"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CEB", "evidence_id": "EV-PDB-8CEB-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8CEB", "doi": "10.1007/s00401-023-02550-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Type2 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BQW", "evidence_id": "EV-PDB-8BQW-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8BQW", "doi": "10.1007/s00401-023-02550-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BQW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BQV", "evidence_id": "EV-PDB-8BQV-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "8BQV", "doi": "10.1007/s00401-023-02550-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y2Q", "evidence_id": "EV-PDB-8Y2Q-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8Y2Q", "doi": "10.1016/j.jbc.2024.107862", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y2Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of spermine induced a-synuclein fibril in Tris buffer."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1KI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,O,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZLO", "evidence_id": "EV-PDB-8ZLO-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8ZLO", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZLO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "F0502B-bound E46K alpha-synuclein fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZLP", "evidence_id": "EV-PDB-8ZLP-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8ZLP", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZLP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "apo WT polymorph 5a alpha-synuclein fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Isoform 1 of Alpha-synuclein (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZVY", "evidence_id": "EV-PDB-8ZVY-2", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.72}, "provenance": {"deposit_id": "8ZVY", "doi": "10.1038/s42003-025-08138-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZVY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Alpha-Synuclein with H2a-H2b dimer complex structure."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZWH", "evidence_id": "EV-PDB-8ZWH-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8ZWH", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Heparin bound E46K alpha-synuclein fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A1A", "evidence_id": "EV-PDB-9A1A-1", "mappings": [{"confidence": "medium", "justification": "Integrative ensemble of the monomer.", "rule": "as-integrative-monomer", "state_id": "aS-disordered", "who": "rule:as-integrative-monomer"}], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A1A", "doi": "10.1016/j.str.2021.05.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A1A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "The ensemble structure of alpha-synuclein monomer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C5R", "evidence_id": "EV-PDB-9C5R-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "9C5R", "doi": "10.1016/j.jbc.2025.108351", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C5R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of recombinantly assembled alpha-synuclein variant fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CD9", "evidence_id": "EV-PDB-9CD9-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9CD9", "doi": "10.1002/1873-3468.15048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CD9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of type II-2 alpha-synuclein filament from multiple system atrophy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,a,b)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CDA", "evidence_id": "EV-PDB-9CDA-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9CDA", "doi": "10.1002/1873-3468.15048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CDA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of type I-2 alpha-synuclein filament from multiple system atrophy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CK3", "evidence_id": "EV-PDB-9CK3-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.04}, "provenance": {"deposit_id": "9CK3", "doi": "10.21769/BioProtoc.5171", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CK3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of in-vitro alpha-synuclein fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CX6", "evidence_id": "EV-PDB-9CX6-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9CX6", "doi": "10.1111/nan.70013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CX6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM filament structure in FTLD-synuclein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D5C", "evidence_id": "EV-PDB-9D5C-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.8}, "provenance": {"deposit_id": "9D5C", "doi": "10.1038/s41589-024-01551-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D5C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9E8U", "evidence_id": "EV-PDB-9E8U-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9E8U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9E8U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "(Apo)Alpha-synuclein fibril structures from MSA patient brain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1BGB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9E8W", "evidence_id": "EV-PDB-9E8W-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9E8W", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9E8W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Complex fibril structure of MSA alpha-synuclein with CNS-11g at 6 hours"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9E9X", "evidence_id": "EV-PDB-9E9X-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9E9X", "doi": "10.1038/s42003-025-08355-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9E9X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments derived from the temporal cortex of the case of atypical multiple system atrophy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EUU", "evidence_id": "EV-PDB-9EUU-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.93}, "provenance": {"deposit_id": "9EUU", "doi": "10.1038/s41586-025-09698-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EUU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HC8", "evidence_id": "EV-PDB-9HC8-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "9HC8", "doi": "10.1101/2025.04.21.649837", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HC8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The L2C alpha-synuclein fibril in the presence of MODAG-005 (short incubation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HCA", "evidence_id": "EV-PDB-9HCA-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9HCA", "doi": "10.1101/2025.04.21.649837", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HCA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The L2A-II alpha-synuclein fibril in the presence of MODAG-005 (long incubation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HCB", "evidence_id": "EV-PDB-9HCB-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9HCB", "doi": "10.1101/2025.04.21.649837", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HCB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The L2C alpha-synuclein fibril in the presence of MODAG-005 (long incubation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HGR", "evidence_id": "EV-PDB-9HGR-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9HGR", "doi": "10.1186/s13024-025-00889-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HGR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "In vitro grown WT Alpha-Synuclein Fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HGS", "evidence_id": "EV-PDB-9HGS-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9HGS", "doi": "10.1002/mds.70030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HGS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "In vitro grown G14R Alpha-Synuclein Fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HXA", "evidence_id": "EV-PDB-9HXA-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9HXA", "doi": "10.1002/mds.70030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HXA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "In vitro grown K58N Alpha-Synuclein Fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["7TT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains B,C,E,G,I,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IJP", "evidence_id": "EV-PDB-9IJP-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9IJP", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IJP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Polyphosphate bound alpha-synuclein fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JC3", "evidence_id": "EV-PDB-9JC3-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "9JC3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JC3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-G51DA53T P1 a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JC5", "evidence_id": "EV-PDB-9JC5-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.23}, "provenance": {"deposit_id": "9JC5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JC5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-G51DA53T P3 a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JD7", "evidence_id": "EV-PDB-9JD7-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.57}, "provenance": {"deposit_id": "9JD7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JD7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-G51DA53T a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JDK", "evidence_id": "EV-PDB-9JDK-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "9JDK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JDK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-G51DA53T P6 a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JE2", "evidence_id": "EV-PDB-9JE2-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "9JE2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JE2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-K58N_G51DA53T a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JE4", "evidence_id": "EV-PDB-9JE4-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.37}, "provenance": {"deposit_id": "9JE4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JE4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-E57A_G51DA53T a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JE6", "evidence_id": "EV-PDB-9JE6-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "9JE6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JE6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-G51DA53T low salt a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JD8", "evidence_id": "EV-PDB-9JD8-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.86}, "provenance": {"deposit_id": "9JD8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JD8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-G51DA53T P5 a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains B,C,D,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JC4", "evidence_id": "EV-PDB-9JC4-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9JC4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JC4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-G51DA53T P2 a-syn fibril."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HC9", "evidence_id": "EV-PDB-9HC9-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "9HC9", "doi": "10.1101/2025.04.21.649837", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HC9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The L2A-I alpha-synuclein fibril in the presence of MODAG-005 (long incubation)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "alpha-synuclein (chains A,B)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A1Q", "evidence_id": "EV-PDB-9A1Q-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A1Q", "doi": "10.1016/j.str.2023.01.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A1Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "The structural models of alpha-synuclein dimer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "alpha-synuclein (chains A,B)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A1H", "evidence_id": "EV-PDB-9A1H-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A1H", "doi": "10.1073/pnas.2201910120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A1H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Integrative structural model of alpha-synuclein compact states bound to membrane mimics"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZWJ", "evidence_id": "EV-PDB-8ZWJ-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8ZWJ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Polyadenylic acid bound alpha-synuclein fibril Polymorph 1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1KI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZMY", "evidence_id": "EV-PDB-8ZMY-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8ZMY", "doi": "10.1073/pnas.2321633121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "F0502B-bound WT polymorph 5a alpha-synuclein fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains F,G,K,L,M,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JI8", "evidence_id": "EV-PDB-9JI8-2", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "9JI8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JI8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein-H21 fibril"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Alpha-synuclein (chains M)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K7Q", "evidence_id": "EV-PDB-9K7Q-2", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.58}, "provenance": {"deposit_id": "9K7Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Parkinson disease protein 7 (DJ-1) and Alpha-synuclein (Alpha-syn) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KA4", "evidence_id": "EV-PDB-9KA4-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "9KA4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KA4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of MSA-like fold (P1) formed under the palette stratagy."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EFL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains L,M,N,P,Q,R,d,e,f,h,i,j)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KCN", "evidence_id": "EV-PDB-9KCN-2", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9KCN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KCN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of FD4-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1B9H"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9O4B", "evidence_id": "EV-PDB-9O4B-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "9O4B", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9O4B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of in-vitro alpha-synuclein fibril bound with Exemplar-6 PET-radioligand"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OBP", "evidence_id": "EV-PDB-9OBP-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "9OBP", "doi": "10.1038/s42003-025-08355-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OBP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of alpha-synuclein filaments derived from the frontal cortex of the case of atypical multiple system atrophy"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains G,H,I,J,K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QYN", "evidence_id": "EV-PDB-9QYN-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.13}, "provenance": {"deposit_id": "9QYN", "doi": "10.1002/advs.202508441", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QYN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein K21A fibril type 1A polymorph in the presence of ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RBB", "evidence_id": "EV-PDB-9RBB-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15}, "provenance": {"deposit_id": "9RBB", "doi": "10.1016/j.neuron.2026.01.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RBB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Wild-type alpha-synuclein fibril - Type 5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,H,I,J,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TPT", "evidence_id": "EV-PDB-9TPT-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "9TPT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TPT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of recombinantly assembled E83Q alpha-synuclein fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EO6"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UFF", "evidence_id": "EV-PDB-9UFF-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9UFF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UFF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BA21-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains O,P,Q,U,V,W)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W09", "evidence_id": "EV-PDB-9W09-2", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9W09", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W09"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of 30-140 P2 a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W08", "evidence_id": "EV-PDB-9W08-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.87}, "provenance": {"deposit_id": "9W08", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W08"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of 30-140 P1 a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W07", "evidence_id": "EV-PDB-9W07-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "9W07", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W07"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Ac-Y39EK45GK58G 30-140 a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W06", "evidence_id": "EV-PDB-9W06-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9W06", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W06"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of Y39EE83G a-syn fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EFL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains c,d,e,f,g,h,i,j,k,o,p,q,r,s,t)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V7C", "evidence_id": "EV-PDB-9V7C-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9V7C", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V7C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of FD4_orientation2 bound Lewy fold fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EFL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains c,d,e,f,g,h,i,j,k,o,p,q,r,s,t)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V6U", "evidence_id": "EV-PDB-9V6U-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9V6U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V6U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of FD4 bound Lewy fold fibril."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UJQ", "evidence_id": "EV-PDB-9UJQ-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9UJQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UJQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of HQY1027-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EPB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UG1", "evidence_id": "EV-PDB-9UG1-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9UG1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UG1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of HA32-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EPK"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UG0", "evidence_id": "EV-PDB-9UG0-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9UG0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UG0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of HA31-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GO3"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UFY", "evidence_id": "EV-PDB-9UFY-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9UFY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UFY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of HA21-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EPA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UFX", "evidence_id": "EV-PDB-9UFX-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9UFX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UFX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of HA11-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UFS", "evidence_id": "EV-PDB-9UFS-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9UFS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UFS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BA23-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UFL", "evidence_id": "EV-PDB-9UFL-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9UFL", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UFL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BA22-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EO8"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains E,F,G,H,I,J,K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UFD", "evidence_id": "EV-PDB-9UFD-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9UFD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UFD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BA12-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EO7"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains E,F,G,H,I,J,K,L,M,N,O,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UF6", "evidence_id": "EV-PDB-9UF6-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9UF6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UF6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BA1-1-bound alpha-synuclein fibril polymorph 6A6B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RBA", "evidence_id": "EV-PDB-9RBA-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54}, "provenance": {"deposit_id": "9RBA", "doi": "10.1016/j.neuron.2026.01.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RBA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Wild-type alpha-synuclein fibril - Type 4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RB9", "evidence_id": "EV-PDB-9RB9-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "9RB9", "doi": "10.1016/j.neuron.2026.01.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RB9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Wild-type alpha-synuclein fibril - Type 3-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RB8", "evidence_id": "EV-PDB-9RB8-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.64}, "provenance": {"deposit_id": "9RB8", "doi": "10.1016/j.neuron.2026.01.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RB8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Wild-type alpha-synuclein fibril - Type 3-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RB7", "evidence_id": "EV-PDB-9RB7-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "9RB7", "doi": "10.1016/j.neuron.2026.01.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RB7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Wild-type alpha-synuclein fibril - Type 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RB6", "evidence_id": "EV-PDB-9RB6-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "9RB6", "doi": "10.1016/j.neuron.2026.01.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RB6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "A53T alpha-synuclein fibril - Type 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RB3", "evidence_id": "EV-PDB-9RB3-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9RB3", "doi": "10.1016/j.neuron.2026.01.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RB3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "A53T alpha-synuclein fibril - Type 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains E,F,G,H,J,K,L,M,N,O,P,Q,e,f,g,h,j,k,l,m,n,o,p,q)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QYL", "evidence_id": "EV-PDB-9QYL-1", "mappings": [{"confidence": "high", "justification": "Structure titled as a fibril, filament or amyloid polymorph.", "rule": "as-fibril-title", "state_id": "aS-fibril", "who": "rule:as-fibril-title"}], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "9QYL", "doi": "10.1002/advs.202508441", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QYL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein fibril type 1A polymorph in the presence of ATP"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PTA", "evidence_id": "EV-PDB-9PTA-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9PTA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PTA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Alpha-synuclein (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PT9", "evidence_id": "EV-PDB-9PT9-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "9PT9", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PT9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Alpha-synuclein B"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Alpha-synuclein (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JO6", "evidence_id": "EV-PDB-9JO6-1", "mappings": [], "molecule_id": "P37840", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9JO6", "doi": "10.31635/ccschem.025.202505587", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JO6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "The complex of alpha-synuclein in the presence of PD6"}
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{"conditions": {"applied_force_pn": null, "buffer": "20mM HEPES", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 7.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Alpha-synuclein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASD2R3/", "evidence_id": "EV-SASBDB-SASD2R3", "mappings": [{"confidence": "low", "justification": "SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex.", "rule": "as-saxs-monomer", "state_id": "aS-disordered", "who": "rule:as-saxs-monomer"}], "molecule_id": "P37840", "observable": {"type": "radius_of_gyration", "uncertainty": 0.014, "unit": "nm", "value": 3.418}, "provenance": {"deposit_id": "SASD2R3", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASD2R3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "α-Synuclein with K to R mutations and different NaCl concentration"}
{"conditions": {"applied_force_pn": null, "buffer": "20mM HEPES", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 7.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Alpha-synuclein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASD2S3/", "evidence_id": "EV-SASBDB-SASD2S3", "mappings": [{"confidence": "low", "justification": "SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex.", "rule": "as-saxs-monomer", "state_id": "aS-disordered", "who": "rule:as-saxs-monomer"}], "molecule_id": "P37840", "observable": {"type": "radius_of_gyration", "uncertainty": 0.025, "unit": "nm", "value": 3.438}, "provenance": {"deposit_id": "SASD2S3", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASD2S3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "α-Synuclein with K to R mutations and different NaCl concentration"}
{"conditions": {"applied_force_pn": null, "buffer": "20mM HEPES", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 7.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Alpha-synuclein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASD2T3/", "evidence_id": "EV-SASBDB-SASD2T3", "mappings": [{"confidence": "low", "justification": "SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex.", "rule": "as-saxs-monomer", "state_id": "aS-disordered", "who": "rule:as-saxs-monomer"}], "molecule_id": "P37840", "observable": {"type": "radius_of_gyration", "uncertainty": 0.017, "unit": "nm", "value": 3.407}, "provenance": {"deposit_id": "SASD2T3", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASD2T3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "α-Synuclein with K to R mutations and different NaCl concentration"}
{"conditions": {"applied_force_pn": null, "buffer": "20mM HEPES", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 7.2, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Alpha-synuclein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASD2U3/", "evidence_id": "EV-SASBDB-SASD2U3", "mappings": [{"confidence": "low", "justification": "SAXS of alpha-synuclein alone, not titled as fibril, oligomer or complex.", "rule": "as-saxs-monomer", "state_id": "aS-disordered", "who": "rule:as-saxs-monomer"}], "molecule_id": "P37840", "observable": {"type": "radius_of_gyration", "uncertainty": 0.013, "unit": "nm", "value": 3.434}, "provenance": {"deposit_id": "SASD2U3", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASD2U3/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "α-Synuclein with K to R mutations and different NaCl concentration"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["78S"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MoeN5,DNA-binding protein 7d (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GWV", "evidence_id": "EV-PDB-5GWV-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "5GWV", "doi": "10.1016/j.bbrc.2019.02.131", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GWV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MoeN5-Sso7d fusion protein in complex with a substrate analogue"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HIV-1 Integrase, Sso7d chimera (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5U1C", "evidence_id": "EV-PDB-5U1C-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "5U1C", "doi": "10.1126/science.aah5163", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5U1C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of tetrameric HIV-1 Strand Transfer Complex Intasome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chimeric Sso7d and HIV-1 integrase (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PUT", "evidence_id": "EV-PDB-6PUT-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6PUT", "doi": "10.1126/science.aay8015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PUT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HIV cleaved synaptic complex (CSC) intasome bound with calcium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["KLQ", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chimeric Sso7d and HIV-1 integrase (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PUW", "evidence_id": "EV-PDB-6PUW-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "6PUW", "doi": "10.1126/science.aay8015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PUW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and Bictegravir (BIC)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "XXJ", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chimeric Sso7d and HIV-1 integrase (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PUZ", "evidence_id": "EV-PDB-6PUZ-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "6PUZ", "doi": "10.1126/science.aay8015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ446 (compound 4f)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "QUW", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chimeric Sso7d and HIV-1 integrase (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6V3K", "evidence_id": "EV-PDB-6V3K-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "6V3K", "doi": "10.1126/science.aay8015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6V3K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ419 (compound 4c)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA-binding protein 7d (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VOY", "evidence_id": "EV-PDB-6VOY-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "6VOY", "doi": "10.1038/s41467-020-16963-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VOY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of HTLV-1 instasome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "OZ1", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Chimeric Sso7d and HIV-1 integrase (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PUY", "evidence_id": "EV-PDB-6PUY-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "6PUY", "doi": "10.1126/science.aay8015", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PUY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ426 (compound 4d)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["C0X"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MoeN5,DNA-binding protein 7d (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6J8W", "evidence_id": "EV-PDB-6J8W-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "6J8W", "doi": "10.1016/j.bbrc.2019.02.131", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6J8W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MOEN5-SSO7D fusion protein in complex with lig 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FAR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MoeN5,DNA-binding protein 7d (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6J8V", "evidence_id": "EV-PDB-6J8V-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.23}, "provenance": {"deposit_id": "6J8V", "doi": "10.1016/j.bbrc.2019.02.131", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6J8V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MOEN5-SSO7D fusion protein in complex with ligand 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BOG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MoeN5,DNA-binding protein 7d (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B0I", "evidence_id": "EV-PDB-5B0I-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.26}, "provenance": {"deposit_id": "5B0I", "doi": "10.1002/anie.201511388", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B0I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MoeN5-Sso7d fusion protein in complex with beta-octyl glucoside"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GPP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MoeN5,DNA-binding protein 7d (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B03", "evidence_id": "EV-PDB-5B03-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5B03", "doi": "10.1002/anie.201511388", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B03"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of MoeN5-Sso7d fusion protein in complex with geranyl pyrophosphate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "MoeN5,DNA-binding protein 7d (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B02", "evidence_id": "EV-PDB-5B02-1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.21}, "provenance": {"deposit_id": "5B02", "doi": "10.1002/anie.201511388", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B02"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the prenyltransferase MoeN5 with a fusion protein tag of Sso7d"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 5.15, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5909", "evidence_id": "EV-BMRB-5909", "mappings": [], "molecule_id": "P39476", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5909", "doi": "10.13018/BMR5909", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5909"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1HN and 15N Chemical Shift Assignments for Sso7d"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-64", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P39476", "evidence_id": "EV-AFDB-AF-P39476-F1", "mappings": [], "molecule_id": "P39476", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 91.38}, "provenance": {"deposit_id": "AF-P39476-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P39476"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P39476-F1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Kinetochore protein NDC80 (chains A,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q84", "evidence_id": "EV-PDB-8Q84-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.15}, "provenance": {"deposit_id": "8Q84", "doi": "10.1126/science.adj8736", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q84"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Outer kinetochore Dam1 protomer dimer Ndc80-Nuf2 coiled-coil complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Kinetochore protein NDC80 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V11", "evidence_id": "EV-PDB-8V11-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "8V11", "doi": "10.1016/j.cub.2024.04.067", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V11"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a Saccharomyces cerevisiae Ipl1 peptide Bound to dwarf Ndc80 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.1, "salt_mM": null, "temperature_c": -195.79}, "construct": {"description": "Kinetochore protein NDC80 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8V10", "evidence_id": "EV-PDB-8V10-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "8V10", "doi": "10.1016/j.cub.2024.04.067", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8V10"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of a Saccharomyces cerevisiae Mps1 peptide bound to dwarf Ndc80 Complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Kinetochore protein NDC80 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q85", "evidence_id": "EV-PDB-8Q85-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.97}, "provenance": {"deposit_id": "8Q85", "doi": "10.1126/science.adj8736", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q85"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Outer kinetochore Dam1 protomer monomer Ndc80-Nuf2 coiled-coil complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Kinetochore protein NDC80 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G0Q", "evidence_id": "EV-PDB-8G0Q-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "8G0Q", "doi": "10.1098/rsob.220378", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G0Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the yeast Ndc80:Nuf2 head region with a bound Dam1 segment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.3, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "NDC80 isoform 1,NDC80 isoform 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KDF", "evidence_id": "EV-PDB-7KDF-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "7KDF", "doi": "10.7554/eLife.65389", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KDF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Stu2 Bound to dwarf Ndc80c"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Kinetochore protein NDC80 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5TD8", "evidence_id": "EV-PDB-5TD8-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.531}, "provenance": {"deposit_id": "5TD8", "doi": "10.1016/j.celrep.2016.10.065", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5TD8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of an Extended Dwarf Ndc80 Complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Kinetochore protein NDC80 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5TCS", "evidence_id": "EV-PDB-5TCS-1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8313}, "provenance": {"deposit_id": "5TCS", "doi": "10.1016/j.celrep.2016.10.065", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5TCS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a Dwarf Ndc80 Tetramer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51814", "evidence_id": "EV-BMRB-51814", "mappings": [], "molecule_id": "P40460", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51814", "doi": "10.13018/BMR51814", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51814"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone Chemical Shift Assignments (1H, 13C, and 15N) for the CH Domain of Yeast Kinetochore Protein Ndc80"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-691", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P40460", "evidence_id": "EV-AFDB-AF-P40460-F1", "mappings": [], "molecule_id": "P40460", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 77.0}, "provenance": {"deposit_id": "AF-P40460-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P40460"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P40460-F1"}
{"components": [], "domains": [], "gene": "GFP", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P42212"}, "ligands": [], "modifications": [{"kind": "ptm", "name": "(Z)-2,3-didehydrotyrosine", "position": 66, "source": "UniProtKB"}], "molecule_id": "P42212", "molecule_type": "protein", "name": "Green fluorescent protein", "organism": {"name": "Aequorea victoria", "taxon_id": 6100}, "provenance": {"deposit_id": "P42212", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42212/entry"}, "record_type": "molecule", "sequence": "MSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFSYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGITHGMDELYK", "sequence_length": 238}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "POV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 2 of Transient receptor potential cation channel subfamily V member 3,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/13LL", "evidence_id": "EV-PDB-13LL-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.96}, "provenance": {"deposit_id": "13LL", "doi": "10.1038/s41467-026-74687-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/13LL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human TRPV3-Q580P Olmsted syndrome mutant in the closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "POV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 2 of Transient receptor potential cation channel subfamily V member 3,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/13LM", "evidence_id": "EV-PDB-13LM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "13LM", "doi": "10.1038/s41467-026-74687-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/13LM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human TRPV3-Q580P Olmsted syndrome mutant in the open state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "POV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 2 of Transient receptor potential cation channel subfamily V member 3,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/13LN", "evidence_id": "EV-PDB-13LN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "13LN", "doi": "10.1038/s41467-026-74687-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/13LN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human TRPV3-Q580P Olmsted syndrome mutant in the inactivated state"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "POV"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 2 of Transient receptor potential cation channel subfamily V member 3,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/13LP", "evidence_id": "EV-PDB-13LP-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "13LP", "doi": "10.1038/s41467-026-74687-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/13LP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human TRPV3-W692G Olmsted syndrome mutant in the inactivated state"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GREEN FLUORESCENT PROTEIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1W7T", "evidence_id": "EV-PDB-1W7T-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1W7T", "doi": "10.1074/JBC.M505473200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1W7T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photoproduct of the Wild-Type Aequorea victoria Green Fluorescent Protein at 100 K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.8, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "GREEN FLUORESCENT PROTEIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1W7U", "evidence_id": "EV-PDB-1W7U-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1W7U", "doi": "10.1074/JBC.M505473200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1W7U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Photoproduct of the Wild-Type Aequorea victoria Green Fluorescent Protein after structural annealing at 170K"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 21.85}, "construct": {"description": "YELLOW FLUORESCENT PROTEIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YFP", "evidence_id": "EV-PDB-1YFP-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1YFP", "doi": "10.1016/S0969-2126(98)00127-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YFP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF YELLOW-EMISSION VARIANT OF GFP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "green fluorescent protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YHG", "evidence_id": "EV-PDB-1YHG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "1YHG", "doi": "10.1021/bi0479205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YHG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Uncyclized precursor structure of S65G Y66S V68G GFP variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YHH", "evidence_id": "EV-PDB-1YHH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1YHH", "doi": "10.1021/bi0479205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YHH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Uncyclized precursor structure of S65A Y66S G67A GFP variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green Fluorescent Protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YHI", "evidence_id": "EV-PDB-1YHI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1YHI", "doi": "10.1021/bi0479205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YHI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Uncyclized precursor structure of S65A Y66S R96A GFP variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green Fluorescent Protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YJ2", "evidence_id": "EV-PDB-1YJ2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1YJ2", "doi": "10.1021/bi0479205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YJ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyclized, non-dehydrated post-translational product for S65A Y66S H148G GFP variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green Fluorescent Protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YJF", "evidence_id": "EV-PDB-1YJF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "1YJF", "doi": "10.1021/bi0479205", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YJF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyclized post-translational product for S65A Y66S (GFPhal) green fluorescent protein variant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Z1P", "evidence_id": "EV-PDB-1Z1P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1Z1P", "doi": "10.1021/bi0503798", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Z1P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Y66L variant of Enhanced Green Fluorescent Protein with 412-nm Absorbing Chromophore"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green Fluorescent Protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1Z1Q", "evidence_id": "EV-PDB-1Z1Q-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "1Z1Q", "doi": "10.1021/bi0503798", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1Z1Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Y66L Variant of Enhanced Green Fluorescent Protein with 374-nm Absorbing Chromophore"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["9PE", "YJ0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 2 (chains C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/24VM", "evidence_id": "EV-PDB-24VM-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54}, "provenance": {"deposit_id": "24VM", "doi": "10.15302/vita.2026.05.0032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/24VM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human wild-type KCNQ2/KCNQ3 heterotetramer (2:2 stoichiometry) in apo state (M2233 WT, without symmetry expansion)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["9PE", "YJ0"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 2 (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/24VR", "evidence_id": "EV-PDB-24VR-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "24VR", "doi": "10.15302/vita.2026.05.0032", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/24VR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human KCNQ2/KCNQ3 heterotetramer (2:2 stoichiometry) in apo state (M2323 apo, with symmetry expansion)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Potassium transporter 5 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/25EX", "evidence_id": "EV-PDB-25EX-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "25EX", "doi": "10.1016/j.molp.2026.08.017", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/25EX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Arabidopsis thaliana potassium transporter 5 in apo state"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein, Bcl-2 homologous antagonist/killer (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5KTG", "evidence_id": "EV-PDB-5KTG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.802}, "provenance": {"deposit_id": "5KTG", "doi": "10.1038/srep30763", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5KTG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of mouse Bak BH3-in-groove homodimer (GFP)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "GFP-17 (chains b,d,f,h,j,l,n,p)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MDR", "evidence_id": "EV-PDB-6MDR-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "6MDR", "doi": "10.1038/s41557-018-0196-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Ceru+32/GFP-17 protomer"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7AMF", "evidence_id": "EV-PDB-7AMF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.63}, "provenance": {"deposit_id": "7AMF", "doi": "10.1002/cphc.202200192", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7AMF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of rsFolder2 in its non-fluorescent off-state"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "CAC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "Green fluorescent protein,Syntaxin-4 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BBJ", "evidence_id": "EV-PDB-8BBJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "8BBJ", "doi": "10.1073/pnas.2309211121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BBJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Secretagogin (mouse) in complex with its target peptide from Syntaxin-4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "BrUSSLEE (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BVG", "evidence_id": "EV-PDB-8BVG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.38}, "provenance": {"deposit_id": "8BVG", "doi": "10.3390/ijms24076403", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BVG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Bright fluorescent protein BrUSLEE with subnanosecond fluorescence lifetime"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein,Tll0404 protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C7I", "evidence_id": "EV-PDB-8C7I-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.12}, "provenance": {"deposit_id": "8C7I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C7I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PS2 assembly factor Psb32 from the cyanobactium Thermosyncechococcus vestitus (formerly elongatus)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DHR", "evidence_id": "EV-PDB-8DHR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "8DHR", "doi": "10.1016/j.jbc.2023.105517", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DHR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "An ester mutant of SfGFP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["D10", "DD9", "GLY", "HEX", "HP6", "NAG", "NBU", "OCT", "UND"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DN2", "evidence_id": "EV-PDB-8DN2-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8DN2", "doi": "10.1038/s41467-023-42051-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, glycine-bound state 2(expanded open)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "D10", "DD9", "HEX", "HP6", "NAG", "NBU", "UND"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DN3", "evidence_id": "EV-PDB-8DN3-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.55}, "provenance": {"deposit_id": "8DN3", "doi": "10.1038/s41467-023-42051-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DN3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, apo state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DD9", "HEX", "LNK", "NAG", "NBU", "OCT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DN4", "evidence_id": "EV-PDB-8DN4-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "8DN4", "doi": "10.1038/s41467-023-42051-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DN4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human Glycine Receptor alpha-1 beta heteromer, glycine-bound state3(desensitized state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["D10", "DD9", "GLY", "HEX", "HP6", "NAG", "NBU", "OCT", "UND"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DN5", "evidence_id": "EV-PDB-8DN5-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "8DN5", "doi": "10.1038/s41467-023-42051-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human Glycine Receptor alpha1-beta heteromer, glycine-bound state1(open state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CO2", "EDO", "MG", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Superfolder green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DPD", "evidence_id": "EV-PDB-8DPD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.51}, "provenance": {"deposit_id": "8DPD", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DPD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "superfolder GFP Tyr74pCNPhe mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PA0", "PEG", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DTA", "evidence_id": "EV-PDB-8DTA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.81}, "provenance": {"deposit_id": "8DTA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DTA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Metal sensitive GFP (mseGFP) complexed with phenylarsine oxide."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["6OU", "BMA", "NAG", "XHO", "Y01", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Sodium channel protein type 5 subunit alpha,Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8F6P", "evidence_id": "EV-PDB-8F6P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8F6P", "doi": "10.1038/s44161-023-00271-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8F6P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Rat Cardiac Sodium Channel with Ranolazine Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "HAUS augmin like complex subunit 2 L homeolog, Green fluorescent protein chimera (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FCK", "evidence_id": "EV-PDB-8FCK-5", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.88}, "provenance": {"deposit_id": "8FCK", "doi": "10.1038/s41467-023-37519-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FCK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the vertebrate augmin complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["UNL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ABC transporter, ATP-binding protein,Green fluorescent protein chimera (chains G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FED", "evidence_id": "EV-PDB-8FED-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "8FED", "doi": "10.1038/s41586-023-06366-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FED"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Talin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VDQ", "evidence_id": "EV-PDB-8VDQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.5}, "provenance": {"deposit_id": "8VDQ", "doi": "10.1038/s41467-024-52581-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VDQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryogenic electron microscopy model of full-length talin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Talin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VDR", "evidence_id": "EV-PDB-8VDR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8VDR", "doi": "10.1038/s41467-024-52581-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryogenic electron microscopy model of full-length talin without R12 and FABD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LBN", "Y01"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CSC1-like protein 2,Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WG3", "evidence_id": "EV-PDB-8WG3-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8WG3", "doi": "10.1038/s41594-024-01411-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "mouse TMEM63b in LMNG-CHS micelle"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Vesicular acetylcholine transporter,Green fluorescent protein,antibody (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XTX", "evidence_id": "EV-PDB-8XTX-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8XTX", "doi": "10.1038/s41594-024-01462-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XTX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human VAChT in an apo conformation"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YA0", "evidence_id": "EV-PDB-8YA0-7", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "8YA0", "doi": "10.1016/j.cell.2025.01.037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YA0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YA2", "evidence_id": "EV-PDB-8YA2-6", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "8YA2", "doi": "10.1016/j.cell.2025.01.037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YA2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+20C)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -258.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZUP", "evidence_id": "EV-PDB-8ZUP-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.2}, "provenance": {"deposit_id": "8ZUP", "doi": "10.1038/s41598-024-73696-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZUP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the F99S/M153T/V163A/T203V/E222Q variant of GFP at pH 8.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -258.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZUQ", "evidence_id": "EV-PDB-8ZUQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "8ZUQ", "doi": "10.1038/s41598-024-73696-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZUQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the F99S/M153T/V163A/T203I/E222Q variant of GFP at pH 8.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -258.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZUR", "evidence_id": "EV-PDB-8ZUR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.2}, "provenance": {"deposit_id": "8ZUR", "doi": "10.1038/s41598-024-73696-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZUR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the F99S/M153T/V163A/T203V/E222Q variant of GFP at pH 5.0"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -258.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZUS", "evidence_id": "EV-PDB-8ZUS-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.2}, "provenance": {"deposit_id": "8ZUS", "doi": "10.1038/s41598-024-73696-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZUS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the F99S/M153T/V163A/T203V variant of GFP at pH 7.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -257.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ZUT", "evidence_id": "EV-PDB-8ZUT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "8ZUT", "doi": "10.1038/s41598-024-73696-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ZUT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the F99S/M153T/V163A variant of GFP at pH 8.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Parvalbumin, Green fluorescent protein chimera (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BCF", "evidence_id": "EV-PDB-9BCF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9BCF", "doi": "10.1002/pro.5226", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BCF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Chimeric protein of crocodile allergen Cro p 1.0101 and GFP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["42H"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "mVenus,Maltose/maltodextrin-binding periplasmic protein,Protein spinster homolog 1,Designed ankyrin repeat protein (DARPin) (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BOI", "evidence_id": "EV-PDB-9BOI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "9BOI", "doi": "10.1073/pnas.2409596121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BOI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of human Spns1 in complex with LPC (18:1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C74", "evidence_id": "EV-PDB-9C74-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.51}, "provenance": {"deposit_id": "9C74", "doi": "10.1039/d4ra05058d", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C74"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "superfolder Green Fluorescent Protein with meta-nitro-tyrosine incorporated at position 66"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AUV", "D10", "D12", "GLU", "GLY", "HEX", "HP6", "NAG", "Y01", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 1,Green fluorescent protein (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7C", "evidence_id": "EV-PDB-9C7C-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9C7C", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AUV", "D10", "D12", "GLU", "GLY", "HEX", "HP6", "NAG", "Y01", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 2A,Green fluorescent protein chimera (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7C", "evidence_id": "EV-PDB-9C7C-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9C7C", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AUV", "D12", "Y01"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 1,Green fluorescent protein chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7E", "evidence_id": "EV-PDB-9C7E-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "9C7E", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (delM653) in nanodisc complex with glycine, glutamate, and GNE-4123, open conformation, C2 symmetry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AUV", "D12", "Y01"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 2A,Green fluorescent protein chimera (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7E", "evidence_id": "EV-PDB-9C7E-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "9C7E", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (delM653) in nanodisc complex with glycine, glutamate, and GNE-4123, open conformation, C2 symmetry"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 1, Green fluorescent protein chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7P", "evidence_id": "EV-PDB-9C7P-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.61}, "provenance": {"deposit_id": "9C7P", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (delM653) in digitonin complexed with glycine, glutamate, and GNE-4123"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 2A, Green fluorescent protein chimera (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7P", "evidence_id": "EV-PDB-9C7P-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.61}, "provenance": {"deposit_id": "9C7P", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (delM653) in digitonin complexed with glycine, glutamate, and GNE-4123"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 1, Green fluorescent protein chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7Q", "evidence_id": "EV-PDB-9C7Q-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.05}, "provenance": {"deposit_id": "9C7Q", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric NMDA receptor GluN1/GluN2A, in complex with glycine and glutamate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 2A, Green fluorescent protein chimera (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7Q", "evidence_id": "EV-PDB-9C7Q-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.05}, "provenance": {"deposit_id": "9C7Q", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric NMDA receptor GluN1/GluN2A, in complex with glycine and glutamate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 1, Green fluorescent protein chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7R", "evidence_id": "EV-PDB-9C7R-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.99}, "provenance": {"deposit_id": "9C7R", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (M817V) in digitonin complexed with glycine, glutamate, and GNE-4123"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, NMDA 2A, Green fluorescent protein chimera (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C7R", "evidence_id": "EV-PDB-9C7R-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.99}, "provenance": {"deposit_id": "9C7R", "doi": "10.1126/sciadv.adx4647", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C7R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Diheteromeric GluN1/GluN2A (M817V) in digitonin complexed with glycine, glutamate, and GNE-4123"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CLA", "evidence_id": "EV-PDB-9CLA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "9CLA", "doi": "10.1038/s41467-026-74630-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CLA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human Kv1.3 mutant-H451V"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Potassium voltage-gated channel subfamily A member 3/mVenus fusion protein,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CLV", "evidence_id": "EV-PDB-9CLV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "9CLV", "doi": "10.1038/s41467-026-74630-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CLV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human Kv1.3 mutant-P424G"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Potassium voltage-gated channel subfamily A member 3/mVenus fusion protein,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CON", "evidence_id": "EV-PDB-9CON-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "9CON", "doi": "10.1038/s41467-026-74630-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CON"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human Kv1.3-H451V with A0194009G09 nanobodies conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Potassium voltage-gated channel subfamily A member 3/mVenus fusion protein,Green fluorescent protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CTY", "evidence_id": "EV-PDB-9CTY-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "9CTY", "doi": "10.1038/s41467-026-74630-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CTY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human Kv1.3-H451V with A0194009G09 nanobodies conformation 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Hemagglutinin HA2 chain, Green fluorescent protein fusion (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9D0Y", "evidence_id": "EV-PDB-9D0Y-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9D0Y", "doi": "10.1038/s41467-025-66375-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9D0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Map of endoH-treated hemagglutinin A/Sing/INFIMH/16"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BR", "EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9F22", "evidence_id": "EV-PDB-9F22-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "9F22", "doi": "10.1038/s42003-025-08352-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9F22"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DARPin eGFP complex DP1 (3G190.24)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1H87", "EDO", "NA", "PXN", "TRS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9F23", "evidence_id": "EV-PDB-9F23-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.59}, "provenance": {"deposit_id": "9F23", "doi": "10.1038/s42003-025-08352-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9F23"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DARPin eGFP complex DP2 (2G156)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9F24", "evidence_id": "EV-PDB-9F24-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.06}, "provenance": {"deposit_id": "9F24", "doi": "10.1038/s42003-025-08352-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9F24"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DARPin eGFP complex DP4 (2G71)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1H9N"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,D(3) dopamine receptor (chains R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9F33", "evidence_id": "EV-PDB-9F33-5", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "9F33", "doi": "10.1038/s41467-024-51993-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9F33"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Dopamine 3 Receptor:Go complex bound to bitopic FOB02-04A - Conformation A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "nowGFP crystallized in Space Group C2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FEN", "evidence_id": "EV-PDB-9FEN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "9FEN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FEN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LSSmOrange (P1) - Directionality of Optical Properties of Fluorescent Proteins"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "NA", "PEG", "PGE", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "wasCFP crystallized in SG P212121 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FEQ", "evidence_id": "EV-PDB-9FEQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "9FEQ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FEQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LSSmOrange (P1) - Directionality of Optical Properties of Fluorescent Proteins"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "nowGFP (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FGI", "evidence_id": "EV-PDB-9FGI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.77}, "provenance": {"deposit_id": "9FGI", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FGI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "LSSmOrange (P1) - Directionality of Optical Properties of Fluorescent Proteins"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BUA", "EPE", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Gamma-aminobutyric acid receptor subunit alpha-5 (chains A,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HAA", "evidence_id": "EV-PDB-9HAA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "9HAA", "doi": "10.1038/s41467-026-74279-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "a5b3 GABAA Receptor resting state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["BUA", "EPE", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Gamma-aminobutyric acid receptor subunit beta-3,Green fluorescent protein (chains B,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HAA", "evidence_id": "EV-PDB-9HAA-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "9HAA", "doi": "10.1038/s41467-026-74279-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "a5b3 GABAA Receptor resting state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ABU", "EPE", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Gamma-aminobutyric acid receptor subunit alpha-5 (chains A,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HUM", "evidence_id": "EV-PDB-9HUM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "9HUM", "doi": "10.1038/s41467-026-74279-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HUM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "a5b3 GABAAR bound to GABA and Mb25 in a desensitized state in saposin nanodiscs after short GABA treatment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ABU", "EPE", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Gamma-aminobutyric acid receptor subunit beta-3,Green fluorescent protein (chains B,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9HUM", "evidence_id": "EV-PDB-9HUM-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "9HUM", "doi": "10.1038/s41467-026-74279-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9HUM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "a5b3 GABAAR bound to GABA and Mb25 in a desensitized state in saposin nanodiscs after short GABA treatment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IRV", "evidence_id": "EV-PDB-9IRV-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "9IRV", "doi": "10.1107/S2052252525003021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IRV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "MultiBody Refinement of dimeric DARPin and its bound GFP on a symmetric scaffold"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Non-structural protein 1,Green fluorescent protein (chains A,B,a,b)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W25", "evidence_id": "EV-PDB-9W25-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.3}, "provenance": {"deposit_id": "9W25", "doi": "10.1038/s41467-026-71970-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DENV2 non-structural protein 1 (NS1) with C-terminal mVenus Conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Piezo-type mechanosensitive ion channel component 2,Green fluorescent protein (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VEF", "evidence_id": "EV-PDB-9VEF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.75}, "provenance": {"deposit_id": "9VEF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VEF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of human Piezo2-MDFIC complex (composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Piezo-type mechanosensitive ion channel component 2,Green fluorescent protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VEE", "evidence_id": "EV-PDB-9VEE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "9VEE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VEE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of human Piezo2-MDFIC2 complex (composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Piezo-type mechanosensitive ion channel component 1,Green fluorescent protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VED", "evidence_id": "EV-PDB-9VED-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "9VED", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VED"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of mouse Piezo1-MDFI complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9U9D", "evidence_id": "EV-PDB-9U9D-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "9U9D", "doi": "10.1021/acs.analchem.5c03831", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9U9D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Bipartite Genetically Encoded Biosensor sG-GECO1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "MAN", "NAG", "THJ", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,alpha-1,2-Mannosidase (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TPA", "evidence_id": "EV-PDB-9TPA-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9TPA", "doi": "10.1101/2025.01.29.635535", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TPA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer)."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZMA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Adenosine receptor A2a,Small exopenicillinase,Green fluorescent protein (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9T9P", "evidence_id": "EV-PDB-9T9P-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9T9P", "doi": "10.1107/S2059798326003785", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9T9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Adenosine receptor A2a (A2AR)-beta-lactamase fusion bound to beta-lactamase inhibitory protein II (BLIPII) and ZM241385"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FDA", "MG", "NAD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ATP-dependent RNA helicase DDX1,Green fluorescent protein (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SPE", "evidence_id": "EV-PDB-9SPE-4", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "9SPE", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SPE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human tRNA ligase complex bound by PYROXD1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1IVP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Hexose transporter 1,Green fluorescent protein (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SDL", "evidence_id": "EV-PDB-9SDL-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.42}, "provenance": {"deposit_id": "9SDL", "doi": "10.1038/s41594-026-01784-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SDL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of PfHT1 bound to 2,5-anhydro-D-mannitol"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: Cyclohexakis-(1-4)-(alpha-D-glucopyranose)"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Green fluorescent protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9S0T", "evidence_id": "EV-PDB-9S0T-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.05}, "provenance": {"deposit_id": "9S0T", "doi": "10.1002/open.202500471", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9S0T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Superfolder green fluorescent protein (sfGFP) exhibiting p-(phenylazo)-L-phenylalanine (Pap) at position 39 in complex with alpha-cyclodextrin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Augmin complex subunit msd5,Green fluorescent protein,Glutathione S-transferase class-mu 26 kDa isozyme (chains K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RPD", "evidence_id": "EV-PDB-9RPD-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.9}, "provenance": {"deposit_id": "9RPD", "doi": "10.1038/s41467-025-63165-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RPD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "D. melanogaster Augmin TII N-clamp (GST-fusion) bound to a microtubule, well-defined subset of particles"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ABU", "EPE", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Gamma-aminobutyric acid receptor subunit beta-3,Green fluorescent protein (chains B,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RPB", "evidence_id": "EV-PDB-9RPB-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9RPB", "doi": "10.1038/s41467-026-74279-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RPB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "a5b3 GABAAR bound to GABA, and Mb25 in a desensitized state in saposin nanodiscs, topiramate-free"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ABU", "EPE", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Gamma-aminobutyric acid receptor subunit alpha-5 (chains A,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RPB", "evidence_id": "EV-PDB-9RPB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9RPB", "doi": "10.1038/s41467-026-74279-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RPB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "a5b3 GABAAR bound to GABA, and Mb25 in a desensitized state in saposin nanodiscs, topiramate-free"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,POU domain, class 5, transcription factor 1 (chains V)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RN2", "evidence_id": "EV-PDB-9RN2-13", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "9RN2", "doi": "10.1016/j.molcel.2026.01.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ABU", "EPE", "NAG", "TOR", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Gamma-aminobutyric acid receptor subunit beta-3,Green fluorescent protein (chains B,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RL5", "evidence_id": "EV-PDB-9RL5-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9RL5", "doi": "10.1038/s41467-026-74279-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RL5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "a5b3 GABAAR bound to Topiramate, GABA, and Mb25 in a desensitized state in saposin nanodiscs"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PTD", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,POU domain, class 5, transcription factor 1 (chains V)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RL4", "evidence_id": "EV-PDB-9RL4-14", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9RL4", "doi": "10.1016/j.molcel.2026.01.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RL4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Green fluorescent protein,Adhesion G protein-coupled receptor L4 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QXL", "evidence_id": "EV-PDB-9QXL-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "9QXL", "doi": "10.1038/s41467-025-67629-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QXL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of ADGRL4 in the active-state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ESX secretion system protein YukB,Green fluorescent protein (chains G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QKS", "evidence_id": "EV-PDB-9QKS-3", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9QKS", "doi": "10.1126/sciadv.ady9587", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QKS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "B subtilis Type VIIb Core Unit (T7bCU) + DUF"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "PEG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9PQC", "evidence_id": "EV-PDB-9PQC-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "9PQC", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9PQC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature crystal structure of enhanced Green Fluorescent Protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, kainate 5,Green fluorescent protein chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OSI", "evidence_id": "EV-PDB-9OSI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "9OSI", "doi": "10.1038/s41467-026-72226-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OSI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The intact LBD state of GluK2/K5 with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Glutamate receptor ionotropic, kainate 5,Green fluorescent protein chimera (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OSF", "evidence_id": "EV-PDB-9OSF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.83}, "provenance": {"deposit_id": "9OSF", "doi": "10.1038/s41467-026-72226-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OSF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The intact LBD state of GluK2/K5 with 5-iodowillardiine and kynurenic acid sodium salt"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 3 of Protein-serine O-palmitoleoyltransferase porcupine,Green fluorescent protein (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OO8", "evidence_id": "EV-PDB-9OO8-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "9OO8", "doi": "10.1038/s42004-025-01726-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OO8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Apo Human PORCN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACY", "GOL", "PEG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fluorescent thiol-disulfide redox biosensor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MUV", "evidence_id": "EV-PDB-9MUV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "9MUV", "doi": "10.1073/pnas.2503978122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MUV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Oxidized state of a turn-on thiol-disulfide redox biosensor with a fluorescence-lifetime readout"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ACT", "EDO", "FMT", "GOL", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Fluorescent thiol-disulfide redox biosensor (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MUT", "evidence_id": "EV-PDB-9MUT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "gfp-structures-native", "state_id": "GFP-native", "who": "rule:gfp-structures-native"}], "molecule_id": "P42212", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "9MUT", "doi": "10.1073/pnas.2503978122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MUT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Reduced state of a turn-on thiol-disulfide redox biosensor with a fluorescence-lifetime readout"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LD0", "evidence_id": "EV-PDB-2LD0-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LD0", "doi": "10.1016/j.bpj.2013.06.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LD0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the N-terminal domain of huntingtin (htt17) in 50 % TFE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LD2", "evidence_id": "EV-PDB-2LD2-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LD2", "doi": "10.1016/j.bpj.2013.06.030", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LD2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the N-terminal domain of huntingtin (htt17) in presence of DPC micelles"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin fusion protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IO4", "evidence_id": "EV-PDB-3IO4-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "3IO4", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IO4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - Crystal C90"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOT", "evidence_id": "EV-PDB-3IOT-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "3IOT", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C92-b"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOV", "evidence_id": "EV-PDB-3IOV-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "3IOV", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C99"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4FEB", "evidence_id": "EV-PDB-4FEB-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "4FEB", "doi": "10.4161/pri.23807", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4FEB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Htt36Q3H-EX1-X1-C2(Beta)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4FEC", "evidence_id": "EV-PDB-4FEC-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "4FEC", "doi": "10.4161/pri.23807", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4FEC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Htt36Q3H"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8W15", "evidence_id": "EV-PDB-8W15-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.72}, "provenance": {"deposit_id": "8W15", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8W15"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "HTT in complex with HAP40 in the apo state."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SAH", "evidence_id": "EV-PDB-8SAH-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8SAH", "doi": "10.1016/j.str.2023.06.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SAH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Huntingtin C-HEAT domain in complex with HAP40"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DXK", "evidence_id": "EV-PDB-7DXK-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "7DXK", "doi": "10.1016/j.str.2021.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DXK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human 128QHuntingtin-HAP40 complex structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DXJ", "evidence_id": "EV-PDB-7DXJ-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7DXJ", "doi": "10.1016/j.str.2021.04.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DXJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human 46QHuntingtin-HAP40 complex structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YEJ", "evidence_id": "EV-PDB-6YEJ-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 18.2}, "provenance": {"deposit_id": "6YEJ", "doi": "10.1016/j.str.2020.06.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YEJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the Full-length disease type human Huntingtin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6X9O", "evidence_id": "EV-PDB-6X9O-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "6X9O", "doi": "10.1038/s42003-021-02895-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6X9O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "High resolution cryoEM structure of huntingtin in complex with HAP40"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6RMH", "evidence_id": "EV-PDB-6RMH-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 9.6}, "provenance": {"deposit_id": "6RMH", "doi": "10.1016/j.str.2020.06.008", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6RMH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The Rigid-body refined model of the normal Huntingtin."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Huntingtin (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N8C", "evidence_id": "EV-PDB-6N8C-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6N8C", "doi": "10.1073/pnas.1821216116", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N8C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Huntingtin (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6EZ8", "evidence_id": "EV-PDB-6EZ8-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "6EZ8", "doi": "10.1038/nature25502", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6EZ8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human Huntingtin-HAP40 complex structure"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4FE8", "evidence_id": "EV-PDB-4FE8-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "4FE8", "doi": "10.4161/pri.23807", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4FE8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Htt36Q3H-EX1-X1-C1(Alpha)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Huntingtin (chains B,D,F,H,J,L,N,P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LRH", "evidence_id": "EV-PDB-3LRH-2", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "3LRH", "doi": "10.1016/j.jmb.2011.09.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LRH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of anti-huntingtin VL domain in complex with huntingtin peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOW", "evidence_id": "EV-PDB-3IOW-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "3IOW", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C99-Hg"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding periplasmic protein,Huntingtin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOU", "evidence_id": "EV-PDB-3IOU-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "3IOU", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C94"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose-binding protein, huntingtin fusion protein (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IOR", "evidence_id": "EV-PDB-3IOR-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "3IOR", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IOR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C95"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Maltose-binding periplasmic protein, HUNTINGTIN FUSION PROTEIN (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3IO6", "evidence_id": "EV-PDB-3IO6-1", "mappings": [], "molecule_id": "P42858", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "3IO6", "doi": "10.1016/j.str.2009.08.002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3IO6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Huntingtin amino-terminal region with 17 Gln residues - crystal C92-a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.2, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17642", "evidence_id": "EV-BMRB-17642", "mappings": [], "molecule_id": "P42858", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17642", "doi": "10.13018/BMR17642", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17642"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of the N-terminal domain of huntingtin (htt17) in 50 % TFE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.0, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=17644", "evidence_id": "EV-BMRB-17644", "mappings": [], "molecule_id": "P42858", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr17644", "doi": "10.13018/BMR17644", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=17644"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of the N-terminal domain of huntingtin (htt17) in presence of DPC micelles"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30545", "evidence_id": "EV-BMRB-30545", "mappings": [], "molecule_id": "P42858", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30545", "doi": "10.13018/BMR30545", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30545"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Structure of the Huttingtin tetramer/dimer mixture determined by paramagnetic NMR"}
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{"conditions": {"applied_force_pn": null, "buffer": "20mM BisTris-HCl, 150mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample.", "ph": 6.5, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Huntingtin", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDQS8/", "evidence_id": "EV-SASBDB-SASDQS8", "mappings": [], "molecule_id": "P42858", "observable": {"type": "radius_of_gyration", "uncertainty": 0.042, "unit": "nm", "value": 4.15}, "provenance": {"deposit_id": "SASDQS8", "doi": "10.1038/s41594-023-00920-0", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDQS8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 19-29; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/19748341", "evidence_id": "EV-DISPROT-DP04129r003", "mappings": [], "molecule_id": "P42858", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 11}, "provenance": {"deposit_id": "DP04129r003", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP04129"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP04129: disorder, residues 19-29"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1-34; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/28085263", "evidence_id": "EV-DISPROT-DP04129r004", "mappings": [], "molecule_id": "P42858", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 34}, "provenance": {"deposit_id": "DP04129r004", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP04129"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP04129: disorder, residues 1-34"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 39-88; evidence: fluorescence resonance energy transfer evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/28937758", "evidence_id": "EV-DISPROT-DP04129r006", "mappings": [], "molecule_id": "P42858", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 50}, "provenance": {"deposit_id": "DP04129r006", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP04129"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "ensemble_fret", "title": "DisProt DP04129: disorder, residues 39-88"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1-38; evidence: fluorescence resonance energy transfer evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/28937758", "evidence_id": "EV-DISPROT-DP04129r007", "mappings": [], "molecule_id": "P42858", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 38}, "provenance": {"deposit_id": "DP04129r007", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP04129"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "ensemble_fret", "title": "DisProt DP04129: disorder, residues 1-38"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Bloom Sydrome recQ helicase like protein (BLM) (chains L,M,N,O)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5U6K", "evidence_id": "EV-PDB-5U6K-2", "mappings": [], "molecule_id": "P54132", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5U6K", "doi": "10.1016/j.str.2017.08.005", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5U6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of TopBP1 BRCT4/5 in complex with a BLM phosphopeptide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BCK", "evidence_id": "EV-PDB-1BCK-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1BCK", "doi": "10.1006/JMBI.1998.2108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BCK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWA", "evidence_id": "EV-PDB-1CWA-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1CWA", "doi": "10.1006/JMBI.1993.1664", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-RAY STRUCTURE OF A MONOMERIC CYCLOPHILIN A-CYCLOSPORIN A CRYSTAL COMPLEX AT 2.1 ANGSTROMS RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWB", "evidence_id": "EV-PDB-1CWB-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "1CWB", "doi": "10.1093/PROTEIN/7.5.597", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWC", "evidence_id": "EV-PDB-1CWC-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "1CWC", "doi": "10.1021/JM00048A002", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWF", "evidence_id": "EV-PDB-1CWF-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "1CWF", "doi": "10.1006/JMBI.1998.2108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWH", "evidence_id": "EV-PDB-1CWH-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "1CWH", "doi": "10.1006/JMBI.1998.2108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH 3-D-SER CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWJ", "evidence_id": "EV-PDB-1CWJ-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1CWJ", "doi": "10.1006/JMBI.1998.2108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWK", "evidence_id": "EV-PDB-1CWK-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1CWK", "doi": "10.1006/JMBI.1998.2108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH 1-(6,7-DIHYDRO)MEBMT 2-VAL 3-D-(2-S-METHYL)SARCOSINE CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWL", "evidence_id": "EV-PDB-1CWL-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1CWL", "doi": "10.1006/JMBI.1998.2108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWM", "evidence_id": "EV-PDB-1CWM-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1CWM", "doi": "10.1006/JMBI.1998.2108", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH 4 MEILE CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.2, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1CWO", "evidence_id": "EV-PDB-1CWO-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "1CWO", "doi": "10.1006/JMBI.1998.2109", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1CWO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HUMAN CYCLOPHILIN A COMPLEXED WITH THR2, LEU5, D-HIV8, LEU10 CYCLOSPORIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CYCLOPHILIN A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1FGL", "evidence_id": "EV-PDB-1FGL-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1FGL", "doi": "10.1016/S0969-2126(97)00172-X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1FGL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cyclophilin A complexed with a fragment of HIV-1 GAG protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CA", "FE", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains C,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1M63", "evidence_id": "EV-PDB-1M63-3", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "1M63", "doi": "10.1073/PNAS.192206699", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1M63"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cyclophilin A (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1M9C", "evidence_id": "EV-PDB-1M9C-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1M9C", "doi": "10.1038/nsb927", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1M9C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type Complex."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3CYS", "evidence_id": "EV-PDB-3CYS-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "3CYS", "doi": "10.1007/BF00156614", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3CYS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "DETERMINATION OF THE NMR SOLUTION STRUCTURE OF THE CYCLOPHILIN A-CYCLOSPORIN A COMPLEX"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cyclophilin A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K0M", "evidence_id": "EV-PDB-3K0M-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.25}, "provenance": {"deposit_id": "3K0M", "doi": "10.1038/nature08615", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K0M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic structure of CypA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "Cyclophilin A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K0N", "evidence_id": "EV-PDB-3K0N-1", "mappings": [{"confidence": "high", "justification": "Room-temperature structure of CypA.", "rule": "curator_assignment", "state_id": "CypA-major", "who": "curator:draft (unreviewed)"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.391}, "provenance": {"deposit_id": "3K0N", "doi": "10.1038/nature08615", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K0N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature structure of CypA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "Cyclophilin A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K0O", "evidence_id": "EV-PDB-3K0O-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "3K0O", "doi": "10.1038/nature08615", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K0O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Room temperature structure of CypA mutant Ser99Thr"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cyclophilin A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K0P", "evidence_id": "EV-PDB-3K0P-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.649}, "provenance": {"deposit_id": "3K0P", "doi": "10.1038/nature08615", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K0P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic structure of CypA mutant Ser99Thr"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cyclophilin A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K0Q", "evidence_id": "EV-PDB-3K0Q-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.317}, "provenance": {"deposit_id": "3K0Q", "doi": "10.1038/nature08615", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K0Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic structure of CypA mutant Ser99Thr (2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cyclophilin A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3K0R", "evidence_id": "EV-PDB-3K0R-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.424}, "provenance": {"deposit_id": "3K0R", "doi": "10.1038/nature08615", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3K0R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Cryogenic structure of CypA mutant Arg55Lys"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cyclophilin A (chains A,C,E,G,I,K,M,O,Q,S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ODI", "evidence_id": "EV-PDB-3ODI-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "3ODI", "doi": "10.1107/S0907444910051905", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ODI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of cyclophilin A in complex with Voclosporin E-ISA247"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cyclophilin A (chains A,C,E,G,I,K,M,O,Q,S)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ODL", "evidence_id": "EV-PDB-3ODL-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.31}, "provenance": {"deposit_id": "3ODL", "doi": "10.1107/S0907444910051905", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ODL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of cyclophilin A in complex with Voclosporin Z-ISA247"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EA4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3RDD", "evidence_id": "EV-PDB-3RDD-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.14}, "provenance": {"deposit_id": "3RDD", "doi": "10.1038/ncomms12777", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3RDD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Cyclophilin A Complexed with an Inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HIS", "PRO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CYCLOPHILIN A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4CYH", "evidence_id": "EV-PDB-4CYH-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "4CYH", "doi": "10.1021/bi960278x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4CYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE HIS-PRO"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IPZ", "evidence_id": "EV-PDB-4IPZ-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.67}, "provenance": {"deposit_id": "4IPZ", "doi": "10.1038/nature12769", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IPZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SmBz bound to Cyclophilin A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["UNU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4N1N", "evidence_id": "EV-PDB-4N1N-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "4N1N", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4N1N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Cyclophilin A in complex with Benzamide."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LSA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4N1O", "evidence_id": "EV-PDB-4N1O-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "4N1O", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4N1O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Cyclophilin A in complex with Saccharin."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6Y9V", "evidence_id": "EV-PDB-6Y9V-2", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.9}, "provenance": {"deposit_id": "6Y9V", "doi": "10.1038/s41594-020-0467-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6Y9V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-8,13)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains A)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6U5G", "evidence_id": "EV-PDB-6U5G-1", "mappings": [], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "6U5G", "doi": "10.1107/S205225252000072X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6U5G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "MicroED structure of a FIB-milled CypA Crystal"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6U5E", "evidence_id": "EV-PDB-6U5E-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.56}, "provenance": {"deposit_id": "6U5E", "doi": "10.1107/S205225252000072X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6U5E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "RT XFEL structure of CypA solved using celloluse carrier media"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5WC7", "evidence_id": "EV-PDB-5WC7-1", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.43}, "provenance": {"deposit_id": "5WC7", "doi": "10.1038/s41467-018-03562-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5WC7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CypA Mutant - I97V S99T C115S"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AOG", "CL", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BG4", "evidence_id": "EV-PDB-9BG4-2", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.14}, "provenance": {"deposit_id": "9BG4", "doi": "10.1021/acs.jmedchem.4c02314", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BG4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Tri-complex of Compound-2, KRAS G12V, and CypA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AHB", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BG5", "evidence_id": "EV-PDB-9BG5-2", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.67}, "provenance": {"deposit_id": "9BG5", "doi": "10.1021/acs.jmedchem.4c02314", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BG5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Tri-complex of Daraxonrasib (RMC-6236), KRAS G13D, and CypA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AHB", "GNP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BG6", "evidence_id": "EV-PDB-9BG6-2", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.66}, "provenance": {"deposit_id": "9BG6", "doi": "10.1021/acs.jmedchem.4c02314", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BG6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Tri-complex of Daraxonrasib (RMC-6236), KRAS G12V, and CypA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GNP", "MG", "ZNI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase A (chains B,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BI1", "evidence_id": "EV-PDB-9BI1-2", "mappings": [{"confidence": "low", "justification": "Experimental structure of CypA; the ground state dominates crystal and NMR structures.", "rule": "cypa-structures-major", "state_id": "CypA-major", "who": "rule:cypa-structures-major"}], "molecule_id": "P62937", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "9BI1", "doi": "10.1038/s41586-024-08283-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BI1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of GMPPNP bound KRAS G12D in complex with CYPA and RMC-7977"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "H3K9me3 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4U68", "evidence_id": "EV-PDB-4U68-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "4U68", "doi": "10.1038/cr.2015.10", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4U68"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Rhino chromodomain in complex with H3K9me3"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GT0", "evidence_id": "EV-PDB-5GT0-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "5GT0", "doi": "10.1016/j.bpc.2016.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GT0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GT3", "evidence_id": "EV-PDB-5GT3-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "5GT3", "doi": "10.1016/j.bpc.2016.11.013", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GT3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of nucleosome particle in the presence of human testis-specific histone variant, hTh2b"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "MN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5GTC", "evidence_id": "EV-PDB-5GTC-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "5GTC", "doi": "10.1021/jacs.7b02138", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5GTC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of complex between DMAP-SH conjugated with a Kaposi's sarcoma herpesvirus LANA peptide (5-15) and nucleosome core particle"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "peptide of Histone H3.1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HJB", "evidence_id": "EV-PDB-5HJB-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "5HJB", "doi": "10.1016/j.molcel.2016.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HJB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "AF9 YEATS in complex with histone H3 Crotonylation at K9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "peptide of Histone H3.1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5HJC", "evidence_id": "EV-PDB-5HJC-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "5HJC", "doi": "10.1016/j.molcel.2016.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5HJC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "BRD3 second bromodomain in complex with histone H3 acetylation at K18"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3K9bu (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6MIQ", "evidence_id": "EV-PDB-6MIQ-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "6MIQ", "doi": "10.1038/s41467-018-07072-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6MIQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Taf14 YEATS domain in complex with histone H3K9bu"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains D,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y5V", "evidence_id": "EV-PDB-7Y5V-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.1}, "provenance": {"deposit_id": "7Y5V", "doi": "10.1126/science.add8673", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y5V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DS8", "evidence_id": "EV-PDB-8DS8-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.84}, "provenance": {"deposit_id": "8DS8", "doi": "10.1038/s41586-023-06688-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DS8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JCD", "evidence_id": "EV-PDB-8JCD-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "8JCD", "doi": "10.1093/nar/gkae825", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JCD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human H2BFWTH100R nucleosome with 601 DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JCC", "evidence_id": "EV-PDB-8JCC-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.42}, "provenance": {"deposit_id": "8JCC", "doi": "10.1093/nar/gkae825", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JCC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human histone H2B variant H2BFWT Cryo-EM structure with 601 DNA sequence"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JBX", "evidence_id": "EV-PDB-8JBX-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "8JBX", "doi": "10.1093/nar/gkae825", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JBX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human canonical 601 DNA nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J6T", "evidence_id": "EV-PDB-8J6T-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.6}, "provenance": {"deposit_id": "8J6T", "doi": "10.1126/science.add8673", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J6T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the double CAF-1 bound right-handed Di-tetrasome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8J6S", "evidence_id": "EV-PDB-8J6S-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8J6S", "doi": "10.1126/science.add8673", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8J6S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the single CAF-1 bound right-handed Di-tetrasome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IQG", "evidence_id": "EV-PDB-8IQG-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8IQG", "doi": "10.1126/science.add8673", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IQG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the monomeric human CAF1-H3-H4 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains D,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IQF", "evidence_id": "EV-PDB-8IQF-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "8IQF", "doi": "10.1126/science.add8673", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IQF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the dimeric human CAF1-H3-H4 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IJ0", "evidence_id": "EV-PDB-8IJ0-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.52}, "provenance": {"deposit_id": "8IJ0", "doi": "10.1073/pnas.2304103120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IJ0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of GAS41 YEATS domain in complex with H3K9ac peptide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IIY", "evidence_id": "EV-PDB-8IIY-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "8IIY", "doi": "10.1073/pnas.2304103120", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IIY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,M,Q,U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IHL", "evidence_id": "EV-PDB-8IHL-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.64}, "provenance": {"deposit_id": "8IHL", "doi": "10.1038/s42003-023-05694-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IHL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Overlapping tri-nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains E,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IEJ", "evidence_id": "EV-PDB-8IEJ-3", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "8IEJ", "doi": "10.1016/j.molcel.2023.08.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IEJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RNF20-RNF40/hRad6A-Ub/nucleosome complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains E,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IEG", "evidence_id": "EV-PDB-8IEG-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "8IEG", "doi": "10.1016/j.molcel.2023.08.001", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IEG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "histone H3Q5his peptide (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HMX", "evidence_id": "EV-PDB-8HMX-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8HMX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HMX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "WDR5 in complex with histone H3Q5his peptide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HAN", "evidence_id": "EV-PDB-8HAN-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "8HAN", "doi": "10.1038/s41467-023-39735-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HAN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8EVH", "evidence_id": "EV-PDB-8EVH-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "8EVH", "doi": "10.1038/s41594-023-01189-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8EVH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CX3CR1 nucleosome and wild type PU.1 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8KCY", "evidence_id": "EV-PDB-8KCY-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8KCY", "doi": "10.1038/s41594-025-01493-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8KCY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of nucleosome complexed with two DEK molecules"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JLA", "evidence_id": "EV-PDB-8JLA-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.44}, "provenance": {"deposit_id": "8JLA", "doi": "10.1093/nar/gkad754", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JLA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains Q)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9GFM", "evidence_id": "EV-PDB-9GFM-8", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9GFM", "doi": "10.1093/nar/gkag138", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9GFM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of the human INO80 core-nucleosome complex state N-7"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IGW", "evidence_id": "EV-PDB-9IGW-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "9IGW", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ku70/80 bound to 147 bp nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IGX", "evidence_id": "EV-PDB-9IGX-5", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "9IGX", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IGX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ku70/80 bound to 153 bp nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9J8M", "evidence_id": "EV-PDB-9J8M-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.82}, "provenance": {"deposit_id": "9J8M", "doi": "10.1038/s41467-025-56823-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9J8M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (High mobility complex)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9J8W", "evidence_id": "EV-PDB-9J8W-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "9J8W", "doi": "10.1038/s41467-025-65486-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9J8W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of NCP-UV-DDB complex containing CPD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JC6", "evidence_id": "EV-PDB-9JC6-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34}, "provenance": {"deposit_id": "9JC6", "doi": "10.1093/nar/gkaf825", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JC6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human H2BW2 nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,L,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MLL", "evidence_id": "EV-PDB-9MLL-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9MLL", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MLL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "GammaH2AX containing nucleosomes, Parallel stack"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MLN", "evidence_id": "EV-PDB-9MLN-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9MLN", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MLN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "GammaH2AX containing nucleosome, Canonical (Class 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MLR", "evidence_id": "EV-PDB-9MLR-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9MLR", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MLR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "GammaH2AX containing nucleosome, Half-wrapped (Class 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MLS", "evidence_id": "EV-PDB-9MLS-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9MLS", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MLS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "GammaH2AX containing nucleosome, Extended (Class 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MMK", "evidence_id": "EV-PDB-9MMK-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9MMK", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MMK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "H2AX containing nucleosome, Canonical (Class 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,L,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MMM", "evidence_id": "EV-PDB-9MMM-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9MMM", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MMM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "H2AX containing nucleosomes, Parallel stack"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,L,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MMO", "evidence_id": "EV-PDB-9MMO-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "9MMO", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MMO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "H2AX containing nucleosomes, Right offset stack"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MMT", "evidence_id": "EV-PDB-9MMT-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9MMT", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MMT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "H2AX containing nucleosome, Unwrapped (Class 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q8X", "evidence_id": "EV-PDB-9Q8X-5", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.94}, "provenance": {"deposit_id": "9Q8X", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q8X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ku70/80 bound to a 153 bp H2AX nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q9F", "evidence_id": "EV-PDB-9Q9F-8", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.54}, "provenance": {"deposit_id": "9Q9F", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q9F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DNA-PK bound to a 153 bp H2AX nucleosome model 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QCR", "evidence_id": "EV-PDB-9QCR-6", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.37}, "provenance": {"deposit_id": "9QCR", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QCR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DNA-PK bound to 153 bp H2AX nucleosome model 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,a,e)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QCS", "evidence_id": "EV-PDB-9QCS-4", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.38}, "provenance": {"deposit_id": "9QCS", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QCS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ku80 mediated DNA-PK dimer bound to 153 bp H2AX nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,a,e)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QMS", "evidence_id": "EV-PDB-9QMS-5", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.0}, "provenance": {"deposit_id": "9QMS", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QMS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DNA-PK bound to 153 bp H2AX nucleosome with ATPyS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R04", "evidence_id": "EV-PDB-9R04-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "9R04", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R04"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "p53 bound to the nucleosome at position SHL-5.7 (crosslinked sample)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R2M", "evidence_id": "EV-PDB-9R2M-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9R2M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R2M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "p53 bound to nucleosome at position SHL+5.9 (non-crosslinked sample, composite map)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R2P", "evidence_id": "EV-PDB-9R2P-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.18}, "provenance": {"deposit_id": "9R2P", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R2P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "p53 bound to nucleosome at position SHL+5.9 (crosslinked sample)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R2Q", "evidence_id": "EV-PDB-9R2Q-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9R2Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R2Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "p53 bound to nucleosome at position SHL-5.7 (non-crosslinked sample)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["COA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R2U", "evidence_id": "EV-PDB-9R2U-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9R2U", "doi": "10.1016/j.molcel.2026.09.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R2U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Drosophila MSL HAT nucleosome complex H4K16ac post-catalytic state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R2W", "evidence_id": "EV-PDB-9R2W-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9R2W", "doi": "10.1016/j.molcel.2026.09.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R2W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Drosophila MSL HAT nucleosome complex H3K36me3 reader state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["COA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R2Y", "evidence_id": "EV-PDB-9R2Y-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9R2Y", "doi": "10.1016/j.molcel.2026.09.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R2Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Drosophila MSL HAT nucleosome complex H4K16ac postcatalytic H3K36me3 reader state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PTD", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RL4", "evidence_id": "EV-PDB-9RL4-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9RL4", "doi": "10.1016/j.molcel.2026.01.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RL4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RMC", "evidence_id": "EV-PDB-9RMC-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "9RMC", "doi": "10.1016/j.molcel.2026.01.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RMC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RN1", "evidence_id": "EV-PDB-9RN1-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.9}, "provenance": {"deposit_id": "9RN1", "doi": "10.1016/j.molcel.2026.01.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RN1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RN2", "evidence_id": "EV-PDB-9RN2-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.1}, "provenance": {"deposit_id": "9RN2", "doi": "10.1016/j.molcel.2026.01.021", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains a,c,e,g)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UJS", "evidence_id": "EV-PDB-9UJS-16", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.62}, "provenance": {"deposit_id": "9UJS", "doi": "10.1016/j.jbc.2026.111340", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UJS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II elongation complex stalled at SHL(-4) of the H3-H4 octasome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UZ7", "evidence_id": "EV-PDB-9UZ7-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "9UZ7", "doi": "10.1093/procel/pwaf094", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UZ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the nucleosome core particle with site-specific DNA-histone crosslinking"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UZ7", "evidence_id": "EV-PDB-9UZ7-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "9UZ7", "doi": "10.1093/procel/pwaf094", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UZ7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the nucleosome core particle with site-specific DNA-histone crosslinking"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V6Q", "evidence_id": "EV-PDB-9V6Q-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.6}, "provenance": {"deposit_id": "9V6Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V6Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of two cPRC1 complexes bound to opposite faces of an endogenous 147-bp mono-nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V6S", "evidence_id": "EV-PDB-9V6S-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9V6S", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V6S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a single cPRC1 complex engaged on one face of an endogenous 147-bp mononucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V6X", "evidence_id": "EV-PDB-9V6X-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9V6X", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V6X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the cPRC1 complex bound to an endogenous 184-bp mono-nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V8L", "evidence_id": "EV-PDB-9V8L-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.6}, "provenance": {"deposit_id": "9V8L", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V8L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the cPRC1-di-nucleosome (loose) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V9H", "evidence_id": "EV-PDB-9V9H-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "9V9H", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the cPRC1-di-nucleosome (tight) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V9P", "evidence_id": "EV-PDB-9V9P-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9V9P", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the cPRC1-di-nucleosome (CBX7) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "GOL", "MYR", "NAD", "PEG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VEM", "evidence_id": "EV-PDB-9VEM-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "9VEM", "doi": "10.1039/d5cb00169b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VEM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIRT2 structure in complex with H3K18myr peptide and native NAD: pre-catalysis state 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "GOL", "MYR", "NAD", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VEW", "evidence_id": "EV-PDB-9VEW-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "9VEW", "doi": "10.1039/d5cb00169b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VEW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIRT2 structure in complex with H3K18myr peptide and native NAD: pre-catalysis state 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains e,g)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UJT", "evidence_id": "EV-PDB-9UJT-16", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.54}, "provenance": {"deposit_id": "9UJT", "doi": "10.1016/j.jbc.2026.111340", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UJT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RNA polymerase II elongation complex stalled at SHL(-0.5) of the H3-H4 octasome (tetrasome)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q80", "evidence_id": "EV-PDB-9Q80-5", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.39}, "provenance": {"deposit_id": "9Q80", "doi": "10.1038/s41467-025-67376-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q80"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Ku70/80 with Ku70 linker and SAP domain bound to a 153 bp H2AX nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,L,P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9MMN", "evidence_id": "EV-PDB-9MMN-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9MMN", "doi": "10.1093/nar/gkaf1028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9MMN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "H2AX containing nucleosomes, Left offset stack"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "MYR", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VG0", "evidence_id": "EV-PDB-9VG0-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.61}, "provenance": {"deposit_id": "9VG0", "doi": "10.1039/d5cb00169b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VG0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIRT2 structure in complex with H3K18myr peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "MYR", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VG3", "evidence_id": "EV-PDB-9VG3-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "9VG3", "doi": "10.1039/d5cb00169b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIRT2 structure in complex with H3K18myr peptide: pre NAD binding state"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "MYR", "NAD", "PEG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Histone H3.1 (chains C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VGZ", "evidence_id": "EV-PDB-9VGZ-2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.34}, "provenance": {"deposit_id": "9VGZ", "doi": "10.1039/d5cb00169b", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VGZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SIRT2-F96A structure in complex with H3K18myr peptide and native NAD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6E", "evidence_id": "EV-PDB-9W6E-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9W6E", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer assembled with DNA truncated at SHL-4.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,O,U,Y)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6F", "evidence_id": "EV-PDB-9W6F-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "9W6F", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle trimer assembled with DNA truncated at SHL-4.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,O,U,Y,e,i)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6G", "evidence_id": "EV-PDB-9W6G-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.02}, "provenance": {"deposit_id": "9W6G", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle tetramer assembled with DNA truncated at SHL-4.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6H", "evidence_id": "EV-PDB-9W6H-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.61}, "provenance": {"deposit_id": "9W6H", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 3) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6I", "evidence_id": "EV-PDB-9W6I-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.61}, "provenance": {"deposit_id": "9W6I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 4) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6J", "evidence_id": "EV-PDB-9W6J-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.62}, "provenance": {"deposit_id": "9W6J", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 1, top NCP) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6K", "evidence_id": "EV-PDB-9W6K-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.71}, "provenance": {"deposit_id": "9W6K", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 1&2, bottom NCP) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6L", "evidence_id": "EV-PDB-9W6L-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.26}, "provenance": {"deposit_id": "9W6L", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 2, top NCP) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6M", "evidence_id": "EV-PDB-9W6M-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.86}, "provenance": {"deposit_id": "9W6M", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 5, top NCP) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6N", "evidence_id": "EV-PDB-9W6N-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.61}, "provenance": {"deposit_id": "9W6N", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 5, bottom NCP) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6O", "evidence_id": "EV-PDB-9W6O-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.08}, "provenance": {"deposit_id": "9W6O", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle dimer (type 6, top NCP) assembled with DNA truncated at SHL-5.5"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Histone H3.1 (chains A,E,K,O,U,Y)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W6Q", "evidence_id": "EV-PDB-9W6Q-1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "9W6Q", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W6Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a stacked human nucleosome core particle trimer assembled with DNA truncated at SHL-5.5"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.4, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=26060", "evidence_id": "EV-BMRB-26060", "mappings": [], "molecule_id": "P68431", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr26060", "doi": "10.13018/BMR26060", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=26060"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution NMR structures of AF9 yeats domain in complex with histone H3 crotonylation at K18"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30177", "evidence_id": "EV-BMRB-30177", "mappings": [], "molecule_id": "P68431", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30177", "doi": "10.13018/BMR30177", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30177"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution NMR structure of PHF20 PHD domain in complex with a histone H3K4me2 peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30501", "evidence_id": "EV-BMRB-30501", "mappings": [], "molecule_id": "P68431", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30501", "doi": "10.13018/BMR30501", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30501"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of ZZZ3 ZZ domain in complex with histone H3 tail"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30502", "evidence_id": "EV-BMRB-30502", "mappings": [], "molecule_id": "P68431", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30502", "doi": "10.13018/BMR30502", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30502"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of ZZZ3 ZZ domain in complex with histone H3K4ac peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=30809", "evidence_id": "EV-BMRB-30809", "mappings": [], "molecule_id": "P68431", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr30809", "doi": "10.13018/BMR30809", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=30809"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of the PHD1 domain of histone demethylase KDM5A in complex with a histone H3(1-10) peptide"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 300 mM NaCl, 1 mM β-mercaptoethanol", "environment": "in_vitro", "ions": [], "ligands": ["partner: Histone H4", "partner: Peptidyl-prolyl cis-trans isomerase FKBP43"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 14.1 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Histone H3.1 with Peptidyl-prolyl cis-trans isomerase FKBP43, Histone H4", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDNS7/", "evidence_id": "EV-SASBDB-SASDNS7", "mappings": [], "molecule_id": "P68431", "observable": {"type": "radius_of_gyration", "uncertainty": 0.047, "unit": "nm", "value": 4.41}, "provenance": {"deposit_id": "SASDNS7", "doi": "10.1016/j.bbagrm.2022.194872", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDNS7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction."}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Tris, 150 mM NaCl, 2 mM β-mercaptoethanol", "environment": "in_vitro", "ions": [], "ligands": ["partner: Histone H4", "partner: PfNPM A3 (1-170)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 13.82 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "Histone H3.1 with PfNPM A3 (1-170), Histone H4", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDVU2/", "evidence_id": "EV-SASBDB-SASDVU2", "mappings": [], "molecule_id": "P68431", "observable": {"type": "radius_of_gyration", "uncertainty": 0.181, "unit": "nm", "value": 4.89}, "provenance": {"deposit_id": "SASDVU2", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDVU2/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Plasmodium falciparum nucleoplasmin (PfNPM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-136", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P68431", "evidence_id": "EV-AFDB-AF-P68431-F1", "mappings": [], "molecule_id": "P68431", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 86.06}, "provenance": {"deposit_id": "AF-P68431-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P68431"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P68431-F1"}
{"components": [], "domains": [], "gene": "adk", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "P69441"}, "ligands": ["AMP", "ATP"], "modifications": [{"kind": "ptm", "name": "N6-acetyllysine", "position": 192, "source": "UniProtKB"}], "molecule_id": "P69441", "molecule_type": "protein", "name": "Adenylate kinase", "organism": {"name": "Escherichia coli (strain K12)", "taxon_id": 83333}, "provenance": {"deposit_id": "P69441", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P69441/entry"}, "record_type": "molecule", "sequence": "MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG", "sequence_length": 214}
{"assumptions": [], "basis": "observed", "description": "Apo enzyme with the LID and NMP domains in the open arrangement, as in 4AKE. Domain definitions to be confirmed by the curator.", "family_label": null, "molecule_id": "P69441", "name": "open (apo)", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P69441.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P69441.yaml"}, "record_type": "state", "representative_model": "ADK-open-cif", "secondary_structure": null, "state_id": "ADK-open", "status": "draft"}
{"assumptions": [], "basis": "observed", "description": "LID and NMP domains closed around the bisubstrate inhibitor Ap5A, as in 1AKE.", "family_label": null, "molecule_id": "P69441", "name": "closed (Ap5A-bound)", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (P69441.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/P69441.yaml"}, "record_type": "state", "representative_model": "ADK-closed-cif", "secondary_structure": null, "state_id": "ADK-closed", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ADENYLATE KINASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1AKE", "evidence_id": "EV-PDB-1AKE-1", "mappings": [{"confidence": "high", "justification": "Ap5A-bound structure with closed LID and NMP domains; representative for ADK-closed.", "rule": "curator_assignment", "state_id": "ADK-closed", "who": "curator:draft (unreviewed)"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "1AKE", "doi": "10.1016/0022-2836(92)90582-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1AKE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF THE COMPLEX BETWEEN ADENYLATE KINASE FROM ESCHERICHIA COLI AND THE INHIBITOR AP5A REFINED AT 1.9 ANGSTROMS RESOLUTION: A MODEL FOR A CATALYTIC TRANSITION STATE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 5.85}, "construct": {"description": "Adenylate kinase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1E4V", "evidence_id": "EV-PDB-1E4V-1", "mappings": [{"confidence": "medium", "justification": "Bisubstrate inhibitor Ap5A (AP5) bound; it closes the LID and NMP domains.", "rule": "adk-ap5a-closed", "state_id": "ADK-closed", "who": "rule:adk-ap5a-closed"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1E4V", "doi": "10.1002/prot.340150106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1E4V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mutant G10V of adenylate kinase from E. coli, modified in the Gly-loop"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": 5.85}, "construct": {"description": "Adenylate kinase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1E4Y", "evidence_id": "EV-PDB-1E4Y-1", "mappings": [{"confidence": "medium", "justification": "Bisubstrate inhibitor Ap5A (AP5) bound; it closes the LID and NMP domains.", "rule": "adk-ap5a-closed", "state_id": "ADK-closed", "who": "rule:adk-ap5a-closed"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "1E4Y", "doi": "10.1002/prot.340150106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1E4Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Mutant P9L of adenylate kinase from E. coli, modified in the Gly-loop"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "AMP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.7, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "ADENYLATE KINASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ECK", "evidence_id": "EV-PDB-2ECK-1", "mappings": [], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "2ECK", "doi": "10.1002/prot.20699", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ECK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "STRUCTURE OF PHOSPHOTRANSFERASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Adenylate kinase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HPQ", "evidence_id": "EV-PDB-3HPQ-1", "mappings": [{"confidence": "medium", "justification": "Bisubstrate inhibitor Ap5A (AP5) bound; it closes the LID and NMP domains.", "rule": "adk-ap5a-closed", "state_id": "ADK-closed", "who": "rule:adk-ap5a-closed"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3HPQ", "doi": "10.1073/pnas.0906510106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HPQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of wild-type adenylate kinase from E. coli, in complex with Ap5A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Adenylate kinase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3HPR", "evidence_id": "EV-PDB-3HPR-1", "mappings": [{"confidence": "medium", "justification": "Bisubstrate inhibitor Ap5A (AP5) bound; it closes the LID and NMP domains.", "rule": "adk-ap5a-closed", "state_id": "ADK-closed", "who": "rule:adk-ap5a-closed"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "3HPR", "doi": "10.1073/pnas.0906510106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3HPR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of V148G adenylate kinase from E. coli, in complex with Ap5A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "ADENYLATE KINASE (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4AKE", "evidence_id": "EV-PDB-4AKE-1", "mappings": [{"confidence": "high", "justification": "Apo structure with open LID and NMP domains; representative for ADK-open. Domain assignment to be confirmed by the curator.", "rule": "curator_assignment", "state_id": "ADK-open", "who": "curator:draft (unreviewed)"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "4AKE", "doi": "10.1016/S0969-2126(96)00018-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4AKE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ADENYLATE KINASE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5", "MG", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Adenylate kinase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X8L", "evidence_id": "EV-PDB-4X8L-1", "mappings": [{"confidence": "medium", "justification": "Bisubstrate inhibitor Ap5A (AP5) bound; it closes the LID and NMP domains.", "rule": "adk-ap5a-closed", "state_id": "ADK-closed", "who": "rule:adk-ap5a-closed"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4X8L", "doi": "10.1038/ncomms8644", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X8L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of E. coli Adenylate kinase P177A mutant in complex with inhibitor Ap5a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Adenylate kinase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4X8M", "evidence_id": "EV-PDB-4X8M-1", "mappings": [{"confidence": "low", "justification": "Crystal structure with no ligand; apo E. coli ADK crystallises open, but this is not checked per entry.", "rule": "adk-apo-open", "state_id": "ADK-open", "who": "rule:adk-apo-open"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "4X8M", "doi": "10.1038/ncomms8644", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4X8M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of E. coli Adenylate kinase Y171W mutant"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5", "MPO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Adenylate kinase (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Q2B", "evidence_id": "EV-PDB-8Q2B-1", "mappings": [{"confidence": "medium", "justification": "Bisubstrate inhibitor Ap5A (AP5) bound; it closes the LID and NMP domains.", "rule": "adk-ap5a-closed", "state_id": "ADK-closed", "who": "rule:adk-ap5a-closed"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.76}, "provenance": {"deposit_id": "8Q2B", "doi": "10.1021/acs.jcim.3c01618", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Q2B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "E. coli Adenylate Kinase variant D158A (AK D158A) showing significant changes to the stacking of catalytic arginine side chains"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["AP5", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Adenylate kinase (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9L14", "evidence_id": "EV-PDB-9L14-1", "mappings": [{"confidence": "medium", "justification": "Bisubstrate inhibitor Ap5A (AP5) bound; it closes the LID and NMP domains.", "rule": "adk-ap5a-closed", "state_id": "ADK-closed", "who": "rule:adk-ap5a-closed"}], "molecule_id": "P69441", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.86}, "provenance": {"deposit_id": "9L14", "doi": "10.1002/1873-3468.70076", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9L14"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the monobody CL-1 in complex with the Escherichia coli adenylate kinase"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cytochrome c (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DUJ", "evidence_id": "EV-PDB-6DUJ-1", "mappings": [], "molecule_id": "P99999", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.82202726164}, "provenance": {"deposit_id": "6DUJ", "doi": "10.1021/acs.jpcb.9b05869", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DUJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of A51V variant of Human Cytochrome c"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -180.15}, "construct": {"description": "Cytochrome c (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6ECJ", "evidence_id": "EV-PDB-6ECJ-1", "mappings": [], "molecule_id": "P99999", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "6ECJ", "doi": "10.1042/BCJ20200793", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6ECJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human cytochrome c G41T"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["HEC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Cytochrome c (chains A,C,E,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6XNK", "evidence_id": "EV-PDB-6XNK-1", "mappings": [], "molecule_id": "P99999", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.08}, "provenance": {"deposit_id": "6XNK", "doi": "10.1021/jacs.2c08325", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6XNK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of dimeric K72A human cytochrome c alkaline conformer"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25418", "evidence_id": "EV-BMRB-25418", "mappings": [], "molecule_id": "P99999", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25418", "doi": "10.13018/BMR25418", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25418"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Human Cytochrome c WT ferric form (oxidized)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25420", "evidence_id": "EV-BMRB-25420", "mappings": [], "molecule_id": "P99999", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25420", "doi": "10.13018/BMR25420", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25420"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments for the ferrous form of the G41S mutant of Human Cytochrome c"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25422", "evidence_id": "EV-BMRB-25422", "mappings": [], "molecule_id": "P99999", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25422", "doi": "10.13018/BMR25422", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25422"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments for the ferric form of the G41S mutant of Human Cytochrome c"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.3, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25660", "evidence_id": "EV-BMRB-25660", "mappings": [], "molecule_id": "P99999", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25660", "doi": "10.13018/BMR25660", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25660"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR structure of the Y48pCMF variant of human cytochrome c in its reduced state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25907", "evidence_id": "EV-BMRB-25907", "mappings": [], "molecule_id": "P99999", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25907", "doi": "10.13018/BMR25907", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25907"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "solution structure of reduced human cytochrome c"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25908", "evidence_id": "EV-BMRB-25908", "mappings": [], "molecule_id": "P99999", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25908", "doi": "10.13018/BMR25908", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25908"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution structure of oxidized human cytochrome c"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.3, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=26578", "evidence_id": "EV-BMRB-26578", "mappings": [], "molecule_id": "P99999", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr26578", "doi": "10.13018/BMR26578", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=26578"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR Assignment of Homo sapiens cytochrome c in its oxidized state"}
{"conditions": {"applied_force_pn": null, "buffer": "Sodium phosphate buffer", "environment": "in_vitro", "ions": [], "ligands": ["partner: SET nuclear proto-oncogene"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16 nm.", "ph": 6.3, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Cytochrome c with SET nuclear proto-oncogene", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDN87/", "evidence_id": "EV-SASBDB-SASDN87", "mappings": [], "molecule_id": "P99999", "observable": {"type": "radius_of_gyration", "uncertainty": 0.063, "unit": "nm", "value": 4.2}, "provenance": {"deposit_id": "SASDN87", "doi": "10.1016/j.csbj.2022.07.009", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDN87/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-105", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/P99999", "evidence_id": "EV-AFDB-AF-P99999-F1", "mappings": [], "molecule_id": "P99999", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 97.94}, "provenance": {"deposit_id": "AF-P99999-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/P99999"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-P99999-F1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["H82"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6I8Z", "evidence_id": "EV-PDB-6I8Z-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "6I8Z", "doi": "10.1021/acs.jmedchem.8b01826", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6I8Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of PTK2 in complex with BI-4464."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 10.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Maltose/maltodextrin-binding periplasmic protein,Focal adhesion kinase 1 (chains A,B,X,Y)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6LES", "evidence_id": "EV-PDB-6LES-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.004}, "provenance": {"deposit_id": "6LES", "doi": "10.1038/s41598-019-56718-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6LES"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "3D domain-swapped dimer of the maltose-binding protein fused to a fragment of the focal adhesion kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["P9K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YR9", "evidence_id": "EV-PDB-6YR9-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.925}, "provenance": {"deposit_id": "6YR9", "doi": "10.1016/j.chembiol.2021.01.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YR9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(2-{[2-(2-oxo-2,3-dihydro-1H-indol-5-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-methyl}-phenyl)-methanesulfonamide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PVT", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YVS", "evidence_id": "EV-PDB-6YVS-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.81}, "provenance": {"deposit_id": "6YVS", "doi": "10.1016/j.chembiol.2021.01.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YVS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 5-{4-[(Pyridin-3-ylmethyl)-amino]-5-trifluoromethyl-pyrimidin-2-ylamino}-1,3-dihydro-indol-2-one"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["Q2H", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YXV", "evidence_id": "EV-PDB-6YXV-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.298}, "provenance": {"deposit_id": "6YXV", "doi": "10.1016/j.chembiol.2021.01.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YXV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-{3-[(2-phenylamino-5-trifluoromethyl-pyrimidin-4-ylamino)-methyl]-pyridin-2-yl}-methanesulfonamide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1JNJ", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SDI", "evidence_id": "EV-PDB-9SDI-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.53}, "provenance": {"deposit_id": "9SDI", "doi": "10.1038/s42004-025-01787-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SDI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 6-(1H-Pyrazol-4-yl)-nicotinic acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF/IHM", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9A8R", "evidence_id": "EV-PDB-9A8R-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9A8R", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9A8R"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "integrative", "title": "Integrative structure of focal adhesion kinase 1 from NMR data"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Isoform 5 of Focal adhesion kinase 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7W9U", "evidence_id": "EV-PDB-7W9U-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.163}, "provenance": {"deposit_id": "7W9U", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7W9U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Isoform 5 of Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7W8I", "evidence_id": "EV-PDB-7W8I-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.943}, "provenance": {"deposit_id": "7W8I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7W8I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Isoform 5 of Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7W8B", "evidence_id": "EV-PDB-7W8B-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.093}, "provenance": {"deposit_id": "7W8B", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7W8B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Isoform 5 of Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7W7Z", "evidence_id": "EV-PDB-7W7Z-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "7W7Z", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7W7Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PKE", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YT6", "evidence_id": "EV-PDB-6YT6-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.537}, "provenance": {"deposit_id": "6YT6", "doi": "10.1016/j.chembiol.2021.01.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YT6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(3-{[2-(2-oxo-2,3-dihydro-1H-indol-5-ylamino)-pyrimidin-4-ylamino]-methyl}-pyridin-2-yl)-methanesulfonamide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "P7N", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YQ1", "evidence_id": "EV-PDB-6YQ1-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.784}, "provenance": {"deposit_id": "6YQ1", "doi": "10.1016/j.chembiol.2021.01.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YQ1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(3-{[2-(2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-methyl}-pyridin-2-yl)-methanesulfonamide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["P4N"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6YOJ", "evidence_id": "EV-PDB-6YOJ-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.361}, "provenance": {"deposit_id": "6YOJ", "doi": "10.1016/j.chembiol.2021.01.003", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6YOJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 19.85}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6PW8", "evidence_id": "EV-PDB-6PW8-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "6PW8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6PW8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["30G"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Q9S", "evidence_id": "EV-PDB-4Q9S-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.07}, "provenance": {"deposit_id": "4Q9S", "doi": "10.1021/jm500669m", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Q9S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of human Focal Adhesion Kinase (Fak) bound to Compound1 (3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)-ONE)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4NY0", "evidence_id": "EV-PDB-4NY0-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "4NY0", "doi": "10.1002/embj.201386399", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4NY0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of FERM domain of human focal adhesion kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["KAO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4KAO", "evidence_id": "EV-PDB-4KAO-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "4KAO", "doi": "10.1016/j.bmcl.2013.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4KAO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-(4-pyridin-3- yl-phenyl)-urea"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K8A"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4K8A", "evidence_id": "EV-PDB-4K8A-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "4K8A", "doi": "10.1016/j.bmcl.2013.07.050", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4K8A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Fragment-based discovery of Focal Adhesion Kinase Inhibitors"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1BR", "IPA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4I4F", "evidence_id": "EV-PDB-4I4F-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "4I4F", "doi": "10.1016/j.bmcl.2013.01.047", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4I4F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Focal Adhesion Kinase catalytic domain in complex with an allosteric binding pyrazolobenzothiazine compound."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["4GU"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GU9", "evidence_id": "EV-PDB-4GU9-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "4GU9", "doi": "10.1021/jm3016014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GU9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Focal adhesion kinase catalytic domain in complex with (2-Fluoro-phenyl)-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["10N"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GU6", "evidence_id": "EV-PDB-4GU6-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "4GU6", "doi": "10.1021/jm3016014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GU6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-{3-[(5-Cyano-2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-ylamino)- methyl]-pyridin-2-yl}-N-methyl-methanesulfonamide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["0PF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EBW", "evidence_id": "EV-PDB-4EBW-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "4EBW", "doi": "10.1016/j.ejmech.2012.06.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EBW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["0O7", "IPA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4EBV", "evidence_id": "EV-PDB-4EBV-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.67}, "provenance": {"deposit_id": "4EBV", "doi": "10.1016/j.ejmech.2012.06.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4EBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3S9O", "evidence_id": "EV-PDB-3S9O-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "3S9O", "doi": "10.1074/jbc.M114.593632", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3S9O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase showing N-terminal interactions in cis"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PXK", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PTK2 protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3PXK", "evidence_id": "EV-PDB-3PXK-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.79}, "provenance": {"deposit_id": "3PXK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3PXK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH Pyrrolo[2,3-d]thiazole"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["YAM"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3BZ3", "evidence_id": "EV-PDB-3BZ3-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "3BZ3", "doi": "10.1158/0008-5472.CAN-07-5155", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3BZ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure Analysis of Focal Adhesion Kinase with a Methanesulfonamide Diaminopyrimidine Inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3B71", "evidence_id": "EV-PDB-3B71-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "3B71", "doi": "10.1016/j.jmb.2007.11.040", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3B71"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CD4 endocytosis motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OW8", "evidence_id": "EV-PDB-1OW8-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "1OW8", "doi": "10.1016/j.str.2003.08.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OW8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Paxillin LD2 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OW7", "evidence_id": "EV-PDB-1OW7-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "1OW7", "doi": "10.1016/j.str.2003.08.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OW7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.3, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Focal adhesion kinase 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1OW6", "evidence_id": "EV-PDB-1OW6-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "1OW6", "doi": "10.1016/j.str.2003.08.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1OW6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FOCAL ADHESION KINASE 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1K05", "evidence_id": "EV-PDB-1K05-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "1K05", "doi": "10.1016/S0969-2126(02)00717-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1K05"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "FOCAL ADHESION KINASE 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1K04", "evidence_id": "EV-PDB-1K04-1", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "1K04", "doi": "10.1016/S0969-2126(02)00717-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1K04"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 565-583; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/12467573", "evidence_id": "EV-DISPROT-DP03144r001", "mappings": [], "molecule_id": "Q05397", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 19}, "provenance": {"deposit_id": "DP03144r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP03144"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP03144: disorder, residues 565-583"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5H1B", "evidence_id": "EV-PDB-5H1B-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "5H1B", "doi": "10.1038/nsmb.3336", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5H1B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human RAD51 presynaptic complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5H1C", "evidence_id": "EV-PDB-5H1C-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "5H1C", "doi": "10.1038/nsmb.3336", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5H1C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human RAD51 post-synaptic complexes"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NP7", "evidence_id": "EV-PDB-5NP7-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.2}, "provenance": {"deposit_id": "5NP7", "doi": "10.1093/nar/gkw783", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NP7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of Human Rad51 on single-stranded DNA to 4.2A resolution."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5NWL", "evidence_id": "EV-PDB-5NWL-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.93}, "provenance": {"deposit_id": "5NWL", "doi": "10.15252/embj.201798162", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5NWL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of a human RAD51-ATP filament."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7C9A", "evidence_id": "EV-PDB-7C9A-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "7C9A", "doi": "10.1038/s41467-020-20258-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7C9A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Human RAD51 post-synaptic complexes mutant (V273P, D274G)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "J46", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EJC", "evidence_id": "EV-PDB-7EJC-2", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "7EJC", "doi": "10.1093/nar/gkab1141", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EJC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "human RAD51 presynaptic complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EJE", "evidence_id": "EV-PDB-7EJE-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.98}, "provenance": {"deposit_id": "7EJE", "doi": "10.1093/nar/gkab1141", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EJE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "human RAD51 post-synaptic complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BQ2", "evidence_id": "EV-PDB-8BQ2-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8BQ2", "doi": "10.1016/j.isci.2023.106689", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BQ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of the pre-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BR2", "evidence_id": "EV-PDB-8BR2-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8BR2", "doi": "10.1016/j.isci.2023.106689", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BR2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of the post-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BSC", "evidence_id": "EV-PDB-8BSC-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8BSC", "doi": "10.1016/j.isci.2023.106689", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BSC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of the RAD51 nucleoprotein filament in the presence of ADP and Ca2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TKI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA repair and recombination protein RadA (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C3J", "evidence_id": "EV-PDB-8C3J-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "8C3J", "doi": "10.1039/d3sc03331g", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C3J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Stapled peptide SP2 in complex with humanised RadA mutant HumRadA22"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8GYK", "evidence_id": "EV-PDB-8GYK-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "8GYK", "doi": "10.1038/s41467-023-40672-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8GYK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of the RAD51_ADP filament"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P,Q,R,S)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JND", "evidence_id": "EV-PDB-8JND-7", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.66}, "provenance": {"deposit_id": "8JND", "doi": "10.1038/s41586-024-07196-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JND"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8RCF", "evidence_id": "EV-PDB-8RCF-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8RCF", "doi": "10.1016/j.molcel.2024.07.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8RCF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51 nucleoprotein filament on double-stranded abasic DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Breast cancer type 2 susceptibility protein, DNA repair protein RAD51 homolog 1 fusion (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UVW", "evidence_id": "EV-PDB-8UVW-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.73}, "provenance": {"deposit_id": "8UVW", "doi": "10.1016/j.molcel.2025.05.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UVW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of RAD51-BRCA2 Cter complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "BEF", "EDO"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "DNA repair protein RAD51 homolog 1,Breast cancer type 2 susceptibility protein (chains D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UVW", "evidence_id": "EV-PDB-8UVW-2", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.73}, "provenance": {"deposit_id": "8UVW", "doi": "10.1016/j.molcel.2025.05.010", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UVW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of RAD51-BRCA2 Cter complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XBT", "evidence_id": "EV-PDB-8XBT-7", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.12}, "provenance": {"deposit_id": "8XBT", "doi": "10.1038/s41586-024-07196-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XBT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the octameric RAD51 ring bound to the nucleosome with the linker DNA binding"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains K,L,M,N,O,P,Q,R,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XBU", "evidence_id": "EV-PDB-8XBU-7", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.24}, "provenance": {"deposit_id": "8XBU", "doi": "10.1038/s41586-024-07196-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XBV", "evidence_id": "EV-PDB-8XBV-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 7.61}, "provenance": {"deposit_id": "8XBV", "doi": "10.1038/s41586-024-07196-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XBV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the sticky end of the nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XBW", "evidence_id": "EV-PDB-8XBW-5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "8XBW", "doi": "10.1038/s41586-024-07196-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XBW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains K,L,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XBX", "evidence_id": "EV-PDB-8XBX-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.36}, "provenance": {"deposit_id": "8XBX", "doi": "10.1038/s41586-024-07196-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XBX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The cryo-EM structure of the RAD51 L2 loop bound to the linker DNA with the blunt end of the nucleosome"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9I62", "evidence_id": "EV-PDB-9I62-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.64}, "provenance": {"deposit_id": "9I62", "doi": "10.7554/eLife.107114", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9I62"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of a RAD51 D-loop"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OMY", "evidence_id": "EV-PDB-9OMY-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.25}, "provenance": {"deposit_id": "9OMY", "doi": "10.1038/s41594-026-01796-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of an octameric RAD51-XRCC3-RAD51C (RAD51-X3C) complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9OMZ", "evidence_id": "EV-PDB-9OMZ-4", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "9OMZ", "doi": "10.1038/s41594-026-01796-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9OMZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of a pentameric RAD51-XRCC3-RAD51C-RAD51D-XRCC2 (51-X3CDX2) complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains G,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q23", "evidence_id": "EV-PDB-9Q23-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "9Q23", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q23"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DX2-CX3-RAD51 structure in the intermediate state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q25", "evidence_id": "EV-PDB-9Q25-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "9Q25", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q25"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DX2-CX3-RAD51 in the closed state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains G,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q28", "evidence_id": "EV-PDB-9Q28-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "9Q28", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q28"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DX2-CX3-RAD51 in the active state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains G,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q29", "evidence_id": "EV-PDB-9Q29-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "9Q29", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q29"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DX2-CX3 structure capping RAD51 filament"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains G,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q2A", "evidence_id": "EV-PDB-9Q2A-4", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.67}, "provenance": {"deposit_id": "9Q2A", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q2A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BCDX2-CX3-RAD51-RAD51-ssDNA supercomplex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains G,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9Q2B", "evidence_id": "EV-PDB-9Q2B-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9Q2B", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9Q2B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "DX2-CX3-RAD51 bound to DNA bubble"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA", "K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QN8", "evidence_id": "EV-PDB-9QN8-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "9QN8", "doi": "10.1073/pnas.2514728122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QN8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51 filament in complex with calcium and ATP bound by the RAD51AP1 C-terminus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QNA", "evidence_id": "EV-PDB-9QNA-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "9QNA", "doi": "10.1073/pnas.2514728122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QNA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51 filament in complex with magnesium and ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QNB", "evidence_id": "EV-PDB-9QNB-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "9QNB", "doi": "10.1073/pnas.2514728122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QNB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51 filament in complex with magnesium and ADP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,C,E,G,I,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9QNC", "evidence_id": "EV-PDB-9QNC-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9QNC", "doi": "10.1073/pnas.2514728122", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9QNC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51 filament in complex with magnesium and ATP bound by the RAD51AP1 C-terminus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SRZ", "evidence_id": "EV-PDB-9SRZ-2", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "9SRZ", "doi": "10.64898/2026.03.22.713441", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SRZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51-ssDNA filament in complex with calcium and ATP bound by the RAD54B N-terminus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SSL", "evidence_id": "EV-PDB-9SSL-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9SSL", "doi": "10.64898/2026.03.22.713441", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SSL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51-ssDNA filament in complex with magnesium and ATP bound by the RAD54B N-terminus (peptide)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "CA", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains E,F,G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SVX", "evidence_id": "EV-PDB-9SVX-6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "9SVX", "doi": "10.1126/science.aea1546", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SVX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XRCC3-RAD51C-RAD51D-XRCC2 (XRCC3 complex) capping a RAD51 filament on single stranded DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "CA", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains E,F,G,H,I,J,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SVY", "evidence_id": "EV-PDB-9SVY-7", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9SVY", "doi": "10.1126/science.aea1546", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SVY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XRCC3-RAD51C-RAD51D-XRCC2 (XRCC3 complex) capping a RAD51 filament on partially duplex DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "CA", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains E,F,G,H,I,J,K)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9SW0", "evidence_id": "EV-PDB-9SW0-2", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9SW0", "doi": "10.1126/science.aea1546", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9SW0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XRCC3-RAD51C-RAD51D-XRCC2 (XRCC3 complex) capping a RAD51 filament on a D-loop intermediate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains A,B,C,D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TRL", "evidence_id": "EV-PDB-9TRL-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9TRL", "doi": "10.64898/2026.03.22.713441", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TRL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51-ssDNA filament in complex with magnesium and ATP bound by the RAD54B N-terminus (beta-barrel)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TRM", "evidence_id": "EV-PDB-9TRM-5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "9TRM", "doi": "10.64898/2026.03.22.713441", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TRM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51-dsDNA filament in complex with calcium and ATP bound by the RAD54B N-terminus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZZR", "evidence_id": "EV-PDB-9ZZR-8", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9ZZR", "doi": "10.1038/s41594-026-01796-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZZR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains E,K,O,W)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZZR", "evidence_id": "EV-PDB-9ZZR-2", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9ZZR", "doi": "10.1038/s41594-026-01796-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZZR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ANP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains R,V)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZZR", "evidence_id": "EV-PDB-9ZZR-1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9ZZR", "doi": "10.1038/s41594-026-01796-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZZR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ATP", "CA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (chains I,J,K,L,M,N)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9TYY", "evidence_id": "EV-PDB-9TYY-3", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "9TYY", "doi": "10.64898/2026.03.22.713441", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9TYY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "RAD51-ssDNA filament in complex with calcium and ATP bound by the RAD54 N-terminus"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.1, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=11046", "evidence_id": "EV-BMRB-11046", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr11046", "doi": "10.13018/BMR11046", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=11046"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "hsRad51-bound ssDNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 29.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=4328", "evidence_id": "EV-BMRB-4328", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr4328", "doi": "10.13018/BMR4328", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=4328"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H, 13C, and 15N Chemical Shift Assignments for Human Rad51(1-114)"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 200 mM Na2SO4, 5% glycerol, 0.1 mM EDTA", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 14.2 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDQ97/", "evidence_id": "EV-SASBDB-SASDQ97", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.007, "unit": "nm", "value": 2.992}, "provenance": {"deposit_id": "SASDQ97", "doi": "10.1002/anie.202312517", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDQ97/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 50 mM Na2SO4, 2% v/v sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 15.6 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDQT9/", "evidence_id": "EV-SASBDB-SASDQT9", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.048, "unit": "nm", "value": 2.857}, "provenance": {"deposit_id": "SASDQT9", "doi": "10.1002/anie.202312517", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDQT9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 200 mM Na2SO4, 5% glycerol, 0.1 mM EDTA", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16.5 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E, A89E, His-Tagged) with Breast cancer type 2 susceptibility protein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDQU9/", "evidence_id": "EV-SASBDB-SASDQU9", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.044, "unit": "nm", "value": 3.026}, "provenance": {"deposit_id": "SASDQU9", "doi": "10.1002/anie.202312517", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDQU9/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 10 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW26/", "evidence_id": "EV-SASBDB-SASDW26", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.793, "unit": "nm", "value": 2.738}, "provenance": {"deposit_id": "SASDW26", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW26/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 10.3 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW36/", "evidence_id": "EV-SASBDB-SASDW36", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.395, "unit": "nm", "value": 2.748}, "provenance": {"deposit_id": "SASDW36", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW36/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 10 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW46/", "evidence_id": "EV-SASBDB-SASDW46", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.219, "unit": "nm", "value": 2.764}, "provenance": {"deposit_id": "SASDW46", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW46/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.6 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW56/", "evidence_id": "EV-SASBDB-SASDW56", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.067, "unit": "nm", "value": 2.731}, "provenance": {"deposit_id": "SASDW56", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW56/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.5 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW66/", "evidence_id": "EV-SASBDB-SASDW66", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 1.488, "unit": "nm", "value": 2.611}, "provenance": {"deposit_id": "SASDW66", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW66/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.6 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW76/", "evidence_id": "EV-SASBDB-SASDW76", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.727, "unit": "nm", "value": 2.663}, "provenance": {"deposit_id": "SASDW76", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW76/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 9.8 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeat 2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW86/", "evidence_id": "EV-SASBDB-SASDW86", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.366, "unit": "nm", "value": 2.705}, "provenance": {"deposit_id": "SASDW86", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW86/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 23 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDW96/", "evidence_id": "EV-SASBDB-SASDW96", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.19, "unit": "nm", "value": 5.455}, "provenance": {"deposit_id": "SASDW96", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDW96/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 21 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWA6/", "evidence_id": "EV-SASBDB-SASDWA6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 5.57, "unit": "nm", "value": 6.045}, "provenance": {"deposit_id": "SASDWA6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWA6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 23 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWB6/", "evidence_id": "EV-SASBDB-SASDWB6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 2.717, "unit": "nm", "value": 5.743}, "provenance": {"deposit_id": "SASDWB6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWB6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-3)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 22 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-3)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWC6/", "evidence_id": "EV-SASBDB-SASDWC6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 1.355, "unit": "nm", "value": 5.686}, "provenance": {"deposit_id": "SASDWC6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWC6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 28 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWD6/", "evidence_id": "EV-SASBDB-SASDWD6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.309, "unit": "nm", "value": 6.658}, "provenance": {"deposit_id": "SASDWD6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWD6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 18 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWE6/", "evidence_id": "EV-SASBDB-SASDWE6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.101, "unit": "nm", "value": 4.563}, "provenance": {"deposit_id": "SASDWE6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWE6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 18.5 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWF6/", "evidence_id": "EV-SASBDB-SASDWF6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 2.689, "unit": "nm", "value": 4.626}, "provenance": {"deposit_id": "SASDWF6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWF6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 18 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWG6/", "evidence_id": "EV-SASBDB-SASDWG6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 1.744, "unit": "nm", "value": 4.544}, "provenance": {"deposit_id": "SASDWG6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWG6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 3-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 18.3 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 3-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWH6/", "evidence_id": "EV-SASBDB-SASDWH6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.904, "unit": "nm", "value": 4.628}, "provenance": {"deposit_id": "SASDWH6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWH6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 21 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWJ6/", "evidence_id": "EV-SASBDB-SASDWJ6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.198, "unit": "nm", "value": 5.259}, "provenance": {"deposit_id": "SASDWJ6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWJ6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 24 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWK6/", "evidence_id": "EV-SASBDB-SASDWK6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 5.647, "unit": "nm", "value": 5.744}, "provenance": {"deposit_id": "SASDWK6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWK6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 21 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWL6/", "evidence_id": "EV-SASBDB-SASDWL6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 2.425, "unit": "nm", "value": 5.513}, "provenance": {"deposit_id": "SASDWL6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWL6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-2)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 23 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-2)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWM6/", "evidence_id": "EV-SASBDB-SASDWM6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 1.188, "unit": "nm", "value": 5.482}, "provenance": {"deposit_id": "SASDWM6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWM6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 34 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWN6/", "evidence_id": "EV-SASBDB-SASDWN6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.475, "unit": "nm", "value": 7.706}, "provenance": {"deposit_id": "SASDWN6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWN6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 33 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWP6/", "evidence_id": "EV-SASBDB-SASDWP6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 5.29, "unit": "nm", "value": 8.132}, "provenance": {"deposit_id": "SASDWP6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWP6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 33.3 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWQ6/", "evidence_id": "EV-SASBDB-SASDWQ6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 2.151, "unit": "nm", "value": 7.622}, "provenance": {"deposit_id": "SASDWQ6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWQ6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 1-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 33 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 1-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWR6/", "evidence_id": "EV-SASBDB-SASDWR6", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 1.158, "unit": "nm", "value": 7.72}, "provenance": {"deposit_id": "SASDWR6", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWR6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.6 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWT5/", "evidence_id": "EV-SASBDB-SASDWT5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.026, "unit": "nm", "value": 2.03}, "provenance": {"deposit_id": "SASDWT5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWT5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.29 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWU5/", "evidence_id": "EV-SASBDB-SASDWU5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.564, "unit": "nm", "value": 2.011}, "provenance": {"deposit_id": "SASDWU5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWU5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.59 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWV5/", "evidence_id": "EV-SASBDB-SASDWV5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.299, "unit": "nm", "value": 2.062}, "provenance": {"deposit_id": "SASDWV5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWV5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.3 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWW5/", "evidence_id": "EV-SASBDB-SASDWW5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.164, "unit": "nm", "value": 2.079}, "provenance": {"deposit_id": "SASDWW5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWW5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeat 4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 6.6 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (Δ97) with Breast cancer type 2 susceptibility protein (BRC repeat 4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDWX5/", "evidence_id": "EV-SASBDB-SASDWX5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.117, "unit": "nm", "value": 2.124}, "provenance": {"deposit_id": "SASDWX5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDWX5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
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{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 28.5 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDX95/", "evidence_id": "EV-SASBDB-SASDX95", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 2.654, "unit": "nm", "value": 6.495}, "provenance": {"deposit_id": "SASDX95", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDX95/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 28.5 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXA5/", "evidence_id": "EV-SASBDB-SASDXA5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 1.424, "unit": "nm", "value": 6.529}, "provenance": {"deposit_id": "SASDXA5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXA5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Hepes, 350 mM KCl, 1 mM DTT, 5% Glycerol", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 28.5 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXB5/", "evidence_id": "EV-SASBDB-SASDXB5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 1.789, "unit": "nm", "value": 6.854}, "provenance": {"deposit_id": "SASDXB5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXB5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM Hepes, 350 mM KCl, 1 mM DTT, 5% Glycerol", "environment": "in_vitro", "ions": [], "ligands": ["partner: Breast cancer type 2 susceptibility protein (BRC repeats 2-4)"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 28.3 nm.", "ph": 7.5, "salt_mM": null, "temperature_c": 15.0}, "construct": {"description": "DNA repair protein RAD51 homolog 1 (F86E A89E) with Breast cancer type 2 susceptibility protein (BRC repeats 2-4)", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXC5/", "evidence_id": "EV-SASBDB-SASDXC5", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "radius_of_gyration", "uncertainty": 0.742, "unit": "nm", "value": 6.771}, "provenance": {"deposit_id": "SASDXC5", "doi": "10.1101/2025.11.13.688182", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXC5/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1-15; evidence: proton-based nuclear magnetic resonance evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/10390347", "evidence_id": "EV-DISPROT-DP01622r001", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 15}, "provenance": {"deposit_id": "DP01622r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01622"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP01622: disorder, residues 1-15"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 86-114; evidence: proton-based nuclear magnetic resonance evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/10390347", "evidence_id": "EV-DISPROT-DP01622r002", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 29}, "provenance": {"deposit_id": "DP01622r002", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01622"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP01622: disorder, residues 86-114"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 1-21; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/27941862", "evidence_id": "EV-DISPROT-DP01622r005", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 21}, "provenance": {"deposit_id": "DP01622r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01622"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP01622: disorder, residues 1-21"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 273-282; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/41337480", "evidence_id": "EV-DISPROT-DP01622r006", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 10}, "provenance": {"deposit_id": "DP01622r006", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01622"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP01622: disorder, residues 273-282"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 273-282; evidence: cryogenic electron microscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/41337480", "evidence_id": "EV-DISPROT-DP01622r007", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 10}, "provenance": {"deposit_id": "DP01622r007", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01622"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP01622: disorder to order, residues 273-282"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 273-282; evidence: cryogenic electron microscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/41337480", "evidence_id": "EV-DISPROT-DP01622r008", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 10}, "provenance": {"deposit_id": "DP01622r008", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01622"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP01622: order, residues 273-282"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-339", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/Q06609", "evidence_id": "EV-AFDB-AF-Q06609-F1", "mappings": [], "molecule_id": "Q06609", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 91.44}, "provenance": {"deposit_id": "AF-Q06609-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/Q06609"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-Q06609-F1"}
{"components": [], "domains": [{"end": 200, "name": "RRM 1", "start": 104}, {"end": 262, "name": "RRM 2", "start": 191}], "gene": "TARDBP", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "Q13148"}, "ligands": [], "modifications": [{"kind": "ptm", "name": "Phosphoserine", "position": 183, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 292, "source": "UniProtKB"}, {"kind": "ptm", "name": "Omega-N-methylarginine", "position": 293, "source": "UniProtKB"}], "molecule_id": "Q13148", "molecule_type": "protein", "name": "TAR DNA-binding protein 43", "organism": {"name": "Homo sapiens", "taxon_id": 9606}, "provenance": {"deposit_id": "Q13148", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q13148/entry"}, "record_type": "molecule", "sequence": "MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM", "sequence_length": 414}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "TAR DNA-binding protein-43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WF0", "evidence_id": "EV-PDB-1WF0-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1WF0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WF0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of RRM domain in TAR DNA-binding protein-43"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "TAR DNA-binding protein-43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2CQG", "evidence_id": "EV-PDB-2CQG-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2CQG", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2CQG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the RNA binding domain of TAR DNA-binding protein-43"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": 39.85}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N2C", "evidence_id": "EV-PDB-2N2C-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N2C", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N2C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR Structure of TDP-43 prion-like hydrophobic helix in DPC"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N3X", "evidence_id": "EV-PDB-2N3X-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N3X", "doi": "10.1038/srep23928", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N3X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution Structure of TDP-43 Amyloidogenic Core Region"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N4P", "evidence_id": "EV-PDB-2N4P-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N4P", "doi": "10.1111/febs.13651", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N4P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the n-terminal domain of tdp-43"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "TAR DNA-BINDING PROTEIN 43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4BS2", "evidence_id": "EV-PDB-4BS2-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "4BS2", "doi": "10.1038/NSMB.2698", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4BS2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4IUF", "evidence_id": "EV-PDB-4IUF-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.752}, "provenance": {"deposit_id": "4IUF", "doi": "10.1093/nar/gkt1407", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4IUF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Y00", "evidence_id": "EV-PDB-4Y00-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "4Y00", "doi": "10.1038/srep21581", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Y00"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -163.15}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4Y0F", "evidence_id": "EV-PDB-4Y0F-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.648}, "provenance": {"deposit_id": "4Y0F", "doi": "10.1038/srep21581", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4Y0F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.9, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5MRG", "evidence_id": "EV-PDB-5MRG-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "5MRG", "doi": "10.1074/jbc.M117.775965", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5MRG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of TDP-43 (residues 1-102)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W50", "evidence_id": "EV-PDB-5W50-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "5W50", "doi": "10.1038/s41594-018-0045-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W50"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the segment, LIIKGI, from the RRM2 of TDP-43, residues 248-253"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W52", "evidence_id": "EV-PDB-5W52-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "5W52", "doi": "10.1038/s41594-018-0045-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W52"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "MicroED structure of the segment, DLIIKGISVHI, from the RRM2 of TDP-43, residues 247-257"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains 0,1,2,3,4,5,6,7,8)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5W7V", "evidence_id": "EV-PDB-5W7V-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "5W7V", "doi": "10.1038/s41594-018-0045-5", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5W7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "NFGTFS (chains A)", "labels": []}, "data_format": "mmCIF", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6CF4", "evidence_id": "EV-PDB-6CF4-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 0.75}, "provenance": {"deposit_id": "6CF4", "doi": "10.1038/s41594-018-0064-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6CF4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "microed", "title": "Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N37", "evidence_id": "EV-PDB-6N37-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "6N37", "doi": "10.1038/s41594-019-0248-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N37"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SegA-sym, conformation of TDP-43 low complexity domain segment A sym"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N3A", "evidence_id": "EV-PDB-6N3A-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6N3A", "doi": "10.1038/s41594-019-0248-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N3A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SegA-long, conformation of TDP-43 low complexity domain segment A long"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "segA long small (chains K,L,M,N,O,P,Q,R,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N3A", "evidence_id": "EV-PDB-6N3A-2", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6N3A", "doi": "10.1038/s41594-019-0248-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N3A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SegA-long, conformation of TDP-43 low complexity domain segment A long"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E,F,G,H,I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N3B", "evidence_id": "EV-PDB-6N3B-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "6N3B", "doi": "10.1038/s41594-019-0248-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N3B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SegA-asym, conformation of TDP-43 low complexity domain segment A asym"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6N3C", "evidence_id": "EV-PDB-6N3C-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6N3C", "doi": "10.1038/s41594-019-0248-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6N3C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SegB, conformation of TDP-43 low complexity domain segment A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,C,E,G,I)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6T4B", "evidence_id": "EV-PDB-6T4B-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.55}, "provenance": {"deposit_id": "6T4B", "doi": "10.1016/j.isci.2020.101159", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6T4B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "CRYSTAL STRUCTURE OF HUMAN TDP-43 N-TERMINAL DOMAIN AT 2.55 A RESOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Isoform 2 of TAR DNA-binding protein 43 (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KWZ", "evidence_id": "EV-PDB-7KWZ-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7KWZ", "doi": "10.1038/s41467-021-21912-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KWZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "TDP-43 LCD amyloid fibrils"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7N9H", "evidence_id": "EV-PDB-7N9H-2", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "7N9H", "doi": "10.1016/j.celrep.2022.111007", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7N9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the mammalian importin a1 bound to the TDP-43 NLS"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Q3U", "evidence_id": "EV-PDB-7Q3U-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7Q3U", "doi": "10.1038/s41593-023-01341-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Q3U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of TDP43 core peptide amyloid fiber"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.8, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "TAR DNA-binding protein 43 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8A6I", "evidence_id": "EV-PDB-8A6I-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8A6I", "doi": "10.1038/s41467-023-36023-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8A6I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of the low complexity domain of TDP-43 (fragment 309-350) with methionine sulfoxide modifications"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CG3", "evidence_id": "EV-PDB-8CG3-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "8CG3", "doi": "10.1038/s41586-023-06405-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CG3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CGG", "evidence_id": "EV-PDB-8CGG-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "8CGG", "doi": "10.1038/s41586-023-06405-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CGG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,U)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8CGH", "evidence_id": "EV-PDB-8CGH-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "8CGH", "doi": "10.1038/s41586-023-06405-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8CGH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QX9", "evidence_id": "EV-PDB-8QX9-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76}, "provenance": {"deposit_id": "8QX9", "doi": "10.1038/s41467-023-44489-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "TDP-43 amyloid fibrils: Morphology-1a"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E,F,G,H,I,J,K,L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QXA", "evidence_id": "EV-PDB-8QXA-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.05}, "provenance": {"deposit_id": "8QXA", "doi": "10.1038/s41467-023-44489-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QXA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "TDP-43 amyloid fibrils: Morphology-1b"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QXB", "evidence_id": "EV-PDB-8QXB-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.86}, "provenance": {"deposit_id": "8QXB", "doi": "10.1038/s41467-023-44489-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QXB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "TDP-43 amyloid fibrils: Morphology-2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TAR DNA-binding protein 43 (chains A,C,E,G,I,q)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9FOF", "evidence_id": "EV-PDB-9FOF-1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9FOF", "doi": "10.1101/2024.06.25.600403", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9FOF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of heteromeric amyloid filament of TDP-43 and AXNA11 from FTLD-TDP Type C (variant 2)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts, 31P chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=19290", "evidence_id": "EV-BMRB-19290", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr19290", "doi": "10.13018/BMR19290", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=19290"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.7, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 1H chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=19922", "evidence_id": "EV-BMRB-19922", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr19922", "doi": "10.13018/BMR19922", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=19922"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments of human TDP-43 RRM2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25659", "evidence_id": "EV-BMRB-25659", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25659", "doi": "10.13018/BMR25659", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25659"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution Structure of TDP-43 Amyloidogenic Core Region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25667", "evidence_id": "EV-BMRB-25667", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25667", "doi": "10.13018/BMR25667", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25667"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution Structure of the G335D Mutant of TDP-43 Amyloidogenic Core Region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": -0.15}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25668", "evidence_id": "EV-BMRB-25668", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25668", "doi": "10.13018/BMR25668", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25668"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Solution Structure of the Q343R Mutant of TDP-43 Amyloidogenic Core Region"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.8, "salt_mM": null, "temperature_c": 14.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51494", "evidence_id": "EV-BMRB-51494", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51494", "doi": "10.13018/BMR51494", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51494"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 low complexity domain with methionine sulfoxide modifications"}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, 3% glycerol", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 4.29 nm.", "ph": 8.5, "salt_mM": null, "temperature_c": 20.0}, "construct": {"description": "TAR DNA-binding protein 43", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDV74/", "evidence_id": "EV-SASBDB-SASDV74", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "radius_of_gyration", "uncertainty": 0.059, "unit": "nm", "value": 1.418}, "provenance": {"deposit_id": "SASDV74", "doi": "10.1038/s42004-025-01522-1", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDV74/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "Semi-synthesis of TDP-43 reveals the effects of phosphorylation in N-terminal domain on self-association"}
{"conditions": {"applied_force_pn": null, "buffer": "20 mM HEPES, 100 mM KCl, 2 mM TCEP", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 16.5 nm.", "ph": 7.6, "salt_mM": null, "temperature_c": 25.0}, "construct": {"description": "TAR DNA-binding protein 43", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXL8/", "evidence_id": "EV-SASBDB-SASDXL8", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "radius_of_gyration", "uncertainty": 0.261, "unit": "nm", "value": 3.98}, "provenance": {"deposit_id": "SASDXL8", "doi": "10.1038/s41467-026-68346-y", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXL8/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "From TDP-43/RNA complex formation to disease-linked TDP-43 aggregation through a structural and cellular approach."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 266-414; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/29511089", "evidence_id": "EV-DISPROT-DP01108r001", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 149}, "provenance": {"deposit_id": "DP01108r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01108"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP01108: disorder, residues 266-414"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 267-414; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/27545621", "evidence_id": "EV-DISPROT-DP01108r005", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 148}, "provenance": {"deposit_id": "DP01108r005", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01108"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP01108: disorder, residues 267-414"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 263-414; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26735904", "evidence_id": "EV-DISPROT-DP01108r013", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 152}, "provenance": {"deposit_id": "DP01108r013", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01108"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP01108: disorder, residues 263-414"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 263-414; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26735904", "evidence_id": "EV-DISPROT-DP01108r014", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 152}, "provenance": {"deposit_id": "DP01108r014", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01108"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP01108: disorder, residues 263-414"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 263-414; evidence: far-UV circular dichroism evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26735904", "evidence_id": "EV-DISPROT-DP01108r020", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 152}, "provenance": {"deposit_id": "DP01108r020", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01108"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cd", "title": "DisProt DP01108: disorder to order, residues 263-414"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 263-414; evidence: nuclear magnetic resonance spectroscopy evidence used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/26735904", "evidence_id": "EV-DISPROT-DP01108r023", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 152}, "provenance": {"deposit_id": "DP01108r023", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP01108"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "nmr_shifts", "title": "DisProt DP01108: disorder to order, residues 263-414"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-414", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/Q13148", "evidence_id": "EV-AFDB-AF-Q13148-F1", "mappings": [], "molecule_id": "Q13148", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 65.19}, "provenance": {"deposit_id": "AF-Q13148-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/Q13148"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-Q13148-F1"}
{"components": [], "domains": [{"end": 39, "name": "WW", "start": 5}, {"end": 163, "name": "PpiC", "start": 52}], "gene": "PIN1", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "Q13526"}, "ligands": [], "modifications": [{"kind": "ptm", "name": "Phosphoserine", "position": 43, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine", "position": 46, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine; by DAPK1", "position": 71, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 108, "source": "UniProtKB"}], "molecule_id": "Q13526", "molecule_type": "protein", "name": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1", "organism": {"name": "Homo sapiens", "taxon_id": 9606}, "provenance": {"deposit_id": "Q13526", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q13526/entry"}, "record_type": "molecule", "sequence": "MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE", "sequence_length": 163}
{"assumptions": [], "basis": "observed", "description": "WW and PPIase domains of Pin1, as in 1PIN. Inter-domain arrangements are not separated.", "family_label": null, "molecule_id": "Q13526", "name": "native fold", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (Q13526.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/Q13526.yaml"}, "record_type": "state", "representative_model": "Pin1-native-cif", "secondary_structure": null, "state_id": "Pin1-native", "status": "draft"}
{"assumptions": ["Treated as a single ensemble; residual structure and intermediates are not resolved.", "Defined by indirect measurements (denaturation, NMR of denatured samples, force spectroscopy); no model is exported."], "basis": "inferred", "description": "Unfolded ensemble reached by denaturant, temperature or force. No observed structure.", "family_label": null, "molecule_id": "Q13526", "name": "unfolded", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (Q13526.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/Q13526.yaml"}, "record_type": "state", "representative_model": null, "secondary_structure": null, "state_id": "Pin1-unfolded", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1I6C", "evidence_id": "EV-PDB-1I6C-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1I6C", "doi": "10.1074/jbc.M010327200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1I6C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF PIN1 WW DOMAIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.4, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (chains B)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1I8H", "evidence_id": "EV-PDB-1I8H-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1I8H", "doi": "10.1074/jbc.M010327200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1I8H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH HUMAN TAU PHOSPHOTHREONINE PEPTIDE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NMV", "evidence_id": "EV-PDB-1NMV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1NMV", "doi": "10.1074/jbc.M300721200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NMV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of human Pin1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NMW", "evidence_id": "EV-PDB-1NMW-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1NMW", "doi": "10.1074/jbc.M300721200", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NMW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of the PPIase domain of human Pin1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PG", "ALA", "PRO", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1PIN", "evidence_id": "EV-PDB-1PIN-1", "mappings": [{"confidence": "high", "justification": "Representative native structure; title and UniProt mapping checked against RCSB.", "rule": "curator_assignment", "state_id": "Pin1-native", "who": "curator:draft (unreviewed)"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.35}, "provenance": {"deposit_id": "1PIN", "doi": "10.1016/S0092-8674(00)80273-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1PIN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM HOMO SAPIENS"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE", "PO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1ZCN", "evidence_id": "EV-PDB-1ZCN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "1ZCN", "doi": "10.1073/pnas.0600511103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1ZCN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "human Pin1 Ng mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F21", "evidence_id": "EV-PDB-2F21-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "2F21", "doi": "10.1073/pnas.0600511103", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "human Pin1 Fip mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 15.05}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KBU", "evidence_id": "EV-PDB-2KBU-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KBU", "doi": "10.1073/pnas.0813012106", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KBU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR solution structure of Pin1 WW domain mutant with beta turn mimic at position 12"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.2, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2KCF", "evidence_id": "EV-PDB-2KCF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2KCF", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2KCF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "The NMR solution structure of the isolated Apo Pin1 WW domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2LB3", "evidence_id": "EV-PDB-2LB3-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2LB3", "doi": "10.1101/gad.2060811", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2LB3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M8I", "evidence_id": "EV-PDB-2M8I-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M8I", "doi": "10.1021/ja405244v", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M8I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of Pin1 WW domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M8J", "evidence_id": "EV-PDB-2M8J-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M8J", "doi": "10.1021/ja405244v", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M8J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Structure of Pin1 WW domain phospho-mimic S16E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M9E", "evidence_id": "EV-PDB-2M9E-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M9E", "doi": "10.1021/ja4040472", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M9E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR solution structure of Pin1 WW domain mutant 5-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M9F", "evidence_id": "EV-PDB-2M9F-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M9F", "doi": "10.1021/ja4040472", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M9F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR solution structure of Pin1 WW domain mutant 5-1g"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M9I", "evidence_id": "EV-PDB-2M9I-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M9I", "doi": "10.1021/ja4040472", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M9I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR solution structure of Pin1 WW domain variant 6-1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2M9J", "evidence_id": "EV-PDB-2M9J-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2M9J", "doi": "10.1021/ja4040472", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2M9J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR solution structure of Pin1 WW domain mutant 6-1g"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2N1O", "evidence_id": "EV-PDB-2N1O-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2N1O", "doi": "10.1038/srep14990", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2N1O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "PIN1 WW domain in complex with a phosphorylated CPEB1 derived peptide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["16P"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2Q5A", "evidence_id": "EV-PDB-2Q5A-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "2Q5A", "doi": "10.1021/cb7000044", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2Q5A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "human Pin1 bound to L-PEPTIDE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.6, "salt_mM": null, "temperature_c": 25.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2RUR", "evidence_id": "EV-PDB-2RUR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "2RUR", "doi": "10.1021/acs.biochem.5b00606", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2RUR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Solution structure of Human Pin1 PPIase C113S mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["12P", "B21"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2XP3", "evidence_id": "EV-PDB-2XP3-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2XP3", "doi": "10.1016/J.BMCL.2010.09.063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2XP3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["12P", "G14"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2XP4", "evidence_id": "EV-PDB-2XP4-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "2XP4", "doi": "10.1016/J.BMCL.2010.09.063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2XP4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["12P", "4FF"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": 3.85}, "construct": {"description": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2XP5", "evidence_id": "EV-PDB-2XP5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "2XP5", "doi": "10.1016/J.BMCL.2010.09.063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2XP5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ODK", "PE4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3ODK", "evidence_id": "EV-PDB-3ODK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "3ODK", "doi": "10.1016/j.bmcl.2010.09.063", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3ODK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["KDH", "PE4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3OOB", "evidence_id": "EV-PDB-3OOB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.89}, "provenance": {"deposit_id": "3OOB", "doi": "10.1158/1940-6207.CAPR-11-0301", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3OOB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structural and functional insights of directly targeting Pin1 by Epigallocatechin-3-gallate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3T5", "P6G"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -196.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TC5", "evidence_id": "EV-PDB-3TC5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "3TC5", "doi": "10.1021/cb2001796", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TC5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Selective targeting of disease-relevant protein binding domains by O-phosphorylated natural product derivatives"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PE4", "R2Z"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TCZ", "evidence_id": "EV-PDB-3TCZ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "3TCZ", "doi": "10.1021/cb3000887", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TCZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 bound to cis peptidomimetic inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3TB", "PE4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3TDB", "evidence_id": "EV-PDB-3TDB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.267}, "provenance": {"deposit_id": "3TDB", "doi": "10.1021/cb3000887", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3TDB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 bound to trans peptidomimetic inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DTT", "O4B", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -73.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3WH0", "evidence_id": "EV-PDB-3WH0-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "3WH0", "doi": "10.1002/anie.201405664", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3WH0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pin1 Complex with 18-crown-6"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LMR"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GWT", "evidence_id": "EV-PDB-4GWT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "4GWT", "doi": "10.1107/S090744491302444X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GWT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FLC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4GWV", "evidence_id": "EV-PDB-4GWV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "4GWV", "doi": "10.1107/S090744491302444X", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4GWV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["PE4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -158.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4QIB", "evidence_id": "EV-PDB-4QIB-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.865}, "provenance": {"deposit_id": "4QIB", "doi": "10.1016/j.bbadis.2014.12.025", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4QIB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Oxidation-Mediated Inhibition of the Peptidyl-Prolyl Isomerase Pin1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["REA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4TNS", "evidence_id": "EV-PDB-4TNS-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.33}, "provenance": {"deposit_id": "4TNS", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4TNS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pin1 PPIase domain bound with all-trans retinoic acid"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["39X", "GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -80.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4TYO", "evidence_id": "EV-PDB-4TYO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.75}, "provenance": {"deposit_id": "4TYO", "doi": "10.1016/j.bmcl.2014.07.044", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4TYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "PPIase in complex with a non-phosphate small molecule inhibitor."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["15P"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4U84", "evidence_id": "EV-PDB-4U84-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.78}, "provenance": {"deposit_id": "4U84", "doi": "10.1016/j.nbd.2014.12.027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4U84"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 with S-hydroxyl-cysteine 113"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["15P"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4U85", "evidence_id": "EV-PDB-4U85-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "4U85", "doi": "10.1016/j.nbd.2014.12.027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4U85"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 with cysteine sulfinic acid 113"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["1PG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4U86", "evidence_id": "EV-PDB-4U86-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "4U86", "doi": "10.1016/j.nbd.2014.12.027", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4U86"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 with cysteine sulfonic acid 113"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CIT", "branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3W", "evidence_id": "EV-PDB-5B3W-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "5B3W", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in C2221 form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3X", "evidence_id": "EV-PDB-5B3X-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "5B3X", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in P41212 form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3Y", "evidence_id": "EV-PDB-5B3Y-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.901}, "provenance": {"deposit_id": "5B3Y", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-23) fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5B3Z", "evidence_id": "EV-PDB-5B3Z-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5B3Z", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5B3Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-39) fused with maltose-binding protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5BMY", "evidence_id": "EV-PDB-5BMY-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.001}, "provenance": {"deposit_id": "5BMY", "doi": "10.1038/srep34654", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5BMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of hPin1 WW domain (5-21) fused with maltose-binding protein"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VTI", "evidence_id": "EV-PDB-5VTI-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "5VTI", "doi": "10.1002/cbic.201700580", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VTI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pin1 WW Domain Sequence 3 with [R,R]-ACPC Loop Substitution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VTJ", "evidence_id": "EV-PDB-5VTJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.5}, "provenance": {"deposit_id": "5VTJ", "doi": "10.1002/cbic.201700580", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pin1 WW Domain Sequence 1 Substituted with [S,S]ACPC"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/5VTK", "evidence_id": "EV-PDB-5VTK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "5VTK", "doi": "10.1002/cbic.201700580", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/5VTK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of Pin1 WW Domain Variant 1 with beta3-Ser Loop Substitution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["TAS"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6DUN", "evidence_id": "EV-PDB-6DUN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.59}, "provenance": {"deposit_id": "6DUN", "doi": "10.1038/s41467-018-05402-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6DUN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure Analysis of PIN1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O33", "evidence_id": "EV-PDB-6O33-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.74}, "provenance": {"deposit_id": "6O33", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O33"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure Analysis of PIN1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2PE", "GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O34", "evidence_id": "EV-PDB-6O34-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.57}, "provenance": {"deposit_id": "6O34", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O34"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure Analysis of PIN1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 4.0}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SVC", "evidence_id": "EV-PDB-6SVC-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6SVC", "doi": "10.1002/anie.202008734", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SVC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Protein allostery of the WW domain at atomic resolution: apo structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 4.0}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SVE", "evidence_id": "EV-PDB-6SVE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6SVE", "doi": "10.1002/anie.202008734", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SVE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Protein allostery of the WW domain at atomic resolution: pCdc25C bound structure"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": 4.0}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6SVH", "evidence_id": "EV-PDB-6SVH-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "6SVH", "doi": "10.1002/anie.202008734", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6SVH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Protein allostery of the WW domain at atomic resolution: FFpSPR bound structure"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["09W", "CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OQA", "evidence_id": "EV-PDB-7OQA-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "7OQA", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OQA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Ternary complex of 14-3-3 sigma, Pin1pS72 phosphopeptide, and WQ162"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SA5", "evidence_id": "EV-PDB-7SA5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7SA5", "doi": "10.1021/jacs.1c06289", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SA5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Two-state solution NMR structure of Apo Pin1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.66, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SG2", "evidence_id": "EV-PDB-8SG2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "8SG2", "doi": "10.7554/eLife.92884", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SG2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "BIVALENT INTERACTIONS OF PIN1 WITH THE C-TERMINAL TAIL OF PKC"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DTT", "P33", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VJF", "evidence_id": "EV-PDB-8VJF-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8VJF", "doi": "10.1073/pnas.2403330121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VJF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human R14A Pin1 covalently bound to inhibitor 158D9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ACH", "DTT", "P33", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.4, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VJG", "evidence_id": "EV-PDB-8VJG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "8VJG", "doi": "10.1073/pnas.2403330121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VJG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human R14A Pin1 covalently bound to inhibitor 164A10"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ED4", "CL", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JZ3", "evidence_id": "EV-PDB-9JZ3-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.98}, "provenance": {"deposit_id": "9JZ3", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JZ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 8 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ED3", "CL", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JZ2", "evidence_id": "EV-PDB-9JZ2-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.55}, "provenance": {"deposit_id": "9JZ2", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JZ2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 7 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ED2", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JYV", "evidence_id": "EV-PDB-9JYV-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "9JYV", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JYV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 6 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EDX", "CL", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JYT", "evidence_id": "EV-PDB-9JYT-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.85}, "provenance": {"deposit_id": "9JYT", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JYT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 1 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EDY", "CL", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JYO", "evidence_id": "EV-PDB-9JYO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "9JYO", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Pin1 and fragment 2 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1D9X", "CIT"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9INP", "evidence_id": "EV-PDB-9INP-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "9INP", "doi": "10.1021/acsmedchemlett.4c00477", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9INP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 (Peptidyl-prolyl cis-trans isomerase) catalytic domain in complex with a covalent inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1D9T"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9INN", "evidence_id": "EV-PDB-9INN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.08}, "provenance": {"deposit_id": "9INN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9INN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 (Peptidyl-prolyl cis-trans isomerase) catalytic domain complexed with a covalent inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1AEM", "PE4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VZ5", "evidence_id": "EV-PDB-8VZ5-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.95}, "provenance": {"deposit_id": "8VZ5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VZ5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of human PIN1 covalently derivatized with SuFEx compound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["DTT", "P33", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VJE", "evidence_id": "EV-PDB-8VJE-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "8VJE", "doi": "10.1073/pnas.2403330121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VJE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human R14A Pin1 covalently bound to inhibitor 158F10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["P33", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VJD", "evidence_id": "EV-PDB-8VJD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.57}, "provenance": {"deposit_id": "8VJD", "doi": "10.1073/pnas.2403330121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VJD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human R14A Pin1 covalently bound to inhibitor 158F10 in P21 21 21 space group"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["FSC", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C3C", "evidence_id": "EV-PDB-8C3C-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "8C3C", "doi": "10.1039/d3sc01732j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C3C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "14-3-3 sigma with Pin1 binding site pS72 and bound Fusicoccin A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "T85"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8C2G", "evidence_id": "EV-PDB-8C2G-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "8C2G", "doi": "10.1039/d3sc01732j", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8C2G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "14-3-3 sigma with Pin1 binding site pS72 and covalently bound CV1040"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SUR", "evidence_id": "EV-PDB-7SUR-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7SUR", "doi": "10.1038/s41467-022-32340-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SUR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Two-state solution NMR structure of Pin1 bound to peptide pCDC25c"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SUQ", "evidence_id": "EV-PDB-7SUQ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7SUQ", "doi": "10.1038/s41467-022-32340-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SUQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Two-state solution NMR structure of Pin1 bound to peptide FFpSPR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "MG", "PEG", "UPK"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.1, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains P)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NRL", "evidence_id": "EV-PDB-7NRL-2", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "7NRL", "doi": "10.1021/jacs.1c03035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NRL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1032"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EFQ", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXK", "evidence_id": "EV-PDB-9KXK-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.96}, "provenance": {"deposit_id": "9KXK", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 54 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ERA", "A1ERB"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V6I", "evidence_id": "EV-PDB-9V6I-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.46}, "provenance": {"deposit_id": "9V6I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V6I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 (Peptidyl-prolyl cis-trans isomerase) catalytic domain in complex with a covalent inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ERA", "A1ERC"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9V6G", "evidence_id": "EV-PDB-9V6G-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "9V6G", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9V6G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human Pin1 (Peptidyl-prolyl cis-trans isomerase) catalytic domain in complex with a covalent inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RPU", "evidence_id": "EV-PDB-9RPU-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9RPU", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RPU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "PIN1 WW Domain Binding Mode with SPY-tide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RPN", "evidence_id": "EV-PDB-9RPN-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "9RPN", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RPN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "PIN1 WW Domain Binding Mode with LYR-tide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1ERZ", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXM", "evidence_id": "EV-PDB-9KXM-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.64}, "provenance": {"deposit_id": "9KXM", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 57 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EVL", "PE4", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXJ", "evidence_id": "EV-PDB-9KXJ-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.57}, "provenance": {"deposit_id": "9KXJ", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 53 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "M4T", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXG", "evidence_id": "EV-PDB-9KXG-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.58}, "provenance": {"deposit_id": "9KXG", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 41 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["53E", "CL", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXD", "evidence_id": "EV-PDB-9KXD-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.6}, "provenance": {"deposit_id": "9KXD", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 37 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EHE", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXC", "evidence_id": "EV-PDB-9KXC-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "9KXC", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 36 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EHD", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KX9", "evidence_id": "EV-PDB-9KX9-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.62}, "provenance": {"deposit_id": "9KX9", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 35 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EHC", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KX7", "evidence_id": "EV-PDB-9KX7-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.53}, "provenance": {"deposit_id": "9KX7", "doi": "10.1016/j.ejmech.2025.118048", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 34 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EHL", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KX1", "evidence_id": "EV-PDB-9KX1-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "9KX1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KX1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 17 complex."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1EFQ", "PE8", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KGO", "evidence_id": "EV-PDB-9KGO-1", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.62}, "provenance": {"deposit_id": "9KGO", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KGO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the PIN1 and fragment 19 complex."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=19291", "evidence_id": "EV-BMRB-19291", "mappings": [{"confidence": "low", "justification": "Chemical shift assignment of the folded protein; shift-only entries rarely describe non-native states unless titled so.", "rule": "pin1-nmr-shifts-native", "state_id": "Pin1-native", "who": "rule:pin1-nmr-shifts-native"}], "molecule_id": "Q13526", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr19291", "doi": "10.13018/BMR19291", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=19291"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR solution structure of Pin1 WW domain mutant 5-1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 7.0, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=35005", "evidence_id": "EV-BMRB-35005", "mappings": [{"confidence": "low", "justification": "Chemical shift assignment of the folded protein; shift-only entries rarely describe non-native states unless titled so.", "rule": "pin1-nmr-shifts-native", "state_id": "Pin1-native", "who": "rule:pin1-nmr-shifts-native"}], "molecule_id": "Q13526", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr35005", "doi": "10.13018/BMR35005", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=35005"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "PIN1 WW Domain Binding Mode with SPY-tide"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": null, "salt_mM": null, "temperature_c": 11.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=4882", "evidence_id": "EV-BMRB-4882", "mappings": [{"confidence": "low", "justification": "Chemical shift assignment of the folded protein; shift-only entries rarely describe non-native states unless titled so.", "rule": "pin1-nmr-shifts-native", "state_id": "Pin1-native", "who": "rule:pin1-nmr-shifts-native"}], "molecule_id": "Q13526", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr4882", "doi": "10.13018/BMR4882", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=4882"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "1H NMR Study on the Binding of Pin1 Trp-trp domain with Phosphothreonine Peptides"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51034", "evidence_id": "EV-BMRB-51034", "mappings": [{"confidence": "low", "justification": "Chemical shift assignment of the folded protein; shift-only entries rarely describe non-native states unless titled so.", "rule": "pin1-nmr-shifts-native", "state_id": "Pin1-native", "who": "rule:pin1-nmr-shifts-native"}], "molecule_id": "Q13526", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51034", "doi": "10.13018/BMR51034", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51034"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "WT Pin1 with pCDC25c ligand"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=51043", "evidence_id": "EV-BMRB-51043", "mappings": [{"confidence": "low", "justification": "Chemical shift assignment of the folded protein; shift-only entries rarely describe non-native states unless titled so.", "rule": "pin1-nmr-shifts-native", "state_id": "Pin1-native", "who": "rule:pin1-nmr-shifts-native"}], "molecule_id": "Q13526", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr51043", "doi": "10.13018/BMR51043", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=51043"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "WT Pin1 with 5x FFpSPR ligand"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.2, "salt_mM": null, "temperature_c": 4.85}, "construct": {"description": "BMRB data: 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5248", "evidence_id": "EV-BMRB-5248", "mappings": [{"confidence": "low", "justification": "Chemical shift assignment of the folded protein; shift-only entries rarely describe non-native states unless titled so.", "rule": "pin1-nmr-shifts-native", "state_id": "Pin1-native", "who": "rule:pin1-nmr-shifts-native"}], "molecule_id": "Q13526", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5248", "doi": "10.13018/BMR5248", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5248"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR Solution Structure of the Isolated Apo Pin1 WW Domain: Comparison to the X-Ray Crystal Structures of Pin 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.6, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 1H chemical shifts, 13C chemical shifts, 15N chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=5305", "evidence_id": "EV-BMRB-5305", "mappings": [{"confidence": "low", "justification": "Chemical shift assignment of the folded protein; shift-only entries rarely describe non-native states unless titled so.", "rule": "pin1-nmr-shifts-native", "state_id": "Pin1-native", "who": "rule:pin1-nmr-shifts-native"}], "molecule_id": "Q13526", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr5305", "doi": "10.13018/BMR5305", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=5305"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Backbone 1H, 13C, and 15N Chemical Shift Assignments for the peptidyl-prolyl cis-trans isomerase Pin1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 39-50; evidence: X-ray crystallography-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/10932246", "evidence_id": "EV-DISPROT-DP02727r001", "mappings": [{"confidence": "medium", "justification": "Experimental structure of this small single-domain protein; deposited structures show the native fold unless the title says otherwise.", "rule": "pin1-structures-native", "state_id": "Pin1-native", "who": "rule:pin1-structures-native"}], "molecule_id": "Q13526", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 12}, "provenance": {"deposit_id": "DP02727r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02727"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "xray", "title": "DisProt DP02727: disorder, residues 39-50"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-163", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/Q13526", "evidence_id": "EV-AFDB-AF-Q13526-F1", "mappings": [{"confidence": "low", "justification": "AlphaFold prediction of the native fold (prediction, not a measurement).", "rule": "pin1-af-native", "state_id": "Pin1-native", "who": "rule:pin1-af-native"}], "molecule_id": "Q13526", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 91.62}, "provenance": {"deposit_id": "AF-Q13526-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/Q13526"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-Q13526-F1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "start 1I6C; Amber Parm99", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/A00M7/overview", "evidence_id": "EV-MDDB-A00M7", "mappings": [{"confidence": "low", "justification": "Simulation started from a native structure (prediction).", "rule": "pin1-md-native", "state_id": "Pin1-native", "who": "rule:pin1-md-native"}], "molecule_id": "Q13526", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 10.0}, "provenance": {"deposit_id": "A00M7", "doi": "10.1016/j.str.2010.07.013", "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/A00M7/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "MoDEL 1I6C"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1PIN-1"], "file": "models/Q13526/Pin1-native.cif", "format": "mmCIF", "model_id": "Pin1-native-cif", "molecule_id": "Q13526", "provenance": {"deposit_id": "1PIN", "doi": "10.1016/S0092-8674(00)80273-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1PIN.cif"}, "record_type": "model", "state_id": "Pin1-native"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-1PIN-1"], "file": "models/Q13526/Pin1-native.pdb", "format": "PDB", "model_id": "Pin1-native-pdb", "molecule_id": "Q13526", "provenance": {"deposit_id": "1PIN", "doi": "10.1016/S0092-8674(00)80273-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/1PIN.pdb"}, "record_type": "model", "state_id": "Pin1-native"}
{"components": [], "domains": [], "gene": "DYNC1H1", "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": null, "rnacentral": null, "uniprot": "Q14204"}, "ligands": ["ATP"], "modifications": [{"kind": "ptm", "name": "N-acetylserine", "position": 2, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 70, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine", "position": 1125, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 1230, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine", "position": 3480, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 4162, "source": "UniProtKB"}, {"kind": "ptm", "name": "N6-acetyllysine", "position": 4283, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine", "position": 4366, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 4368, "source": "UniProtKB"}], "molecule_id": "Q14204", 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"sequence_length": 4646}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PQY", "evidence_id": "EV-PDB-8PQY-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8PQY", "doi": "10.1126/science.adk8544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PQY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cytoplasmic dynein-1 motor domain bound to LIS1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PQZ", "evidence_id": "EV-PDB-8PQZ-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.5}, "provenance": {"deposit_id": "8PQZ", "doi": "10.1126/science.adk8544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PQZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cytoplasmic dynein-1 A1/A2 motor domains bound to LIS1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PR0", "evidence_id": "EV-PDB-8PR0-5", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 9.4}, "provenance": {"deposit_id": "8PR0", "doi": "10.1126/science.adk8544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PR0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cytoplasmic dynein-A heavy chain bound to dynactin-p150glued and IC-LC tower"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PR1", "evidence_id": "EV-PDB-8PR1-4", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 8.2}, "provenance": {"deposit_id": "8PR1", "doi": "10.1126/science.adk8544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PR1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cytoplasmic dynein-B heavy chain bound to IC-LC tower"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains f,m)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PR2", "evidence_id": "EV-PDB-8PR2-2", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "8PR2", "doi": "10.1126/science.adk8544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PR2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains f,m)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PR3", "evidence_id": "EV-PDB-8PR3-2", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8PR3", "doi": "10.1126/science.adk8544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PR3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ANP", "ATP", "MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains e,f,m,n)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8PTK", "evidence_id": "EV-PDB-8PTK-15", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 10.0}, "provenance": {"deposit_id": "8PTK", "doi": "10.1126/science.adk8544", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8PTK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Composite structure of Dynein-Dynactin-JIP3-LIS1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BLY", "evidence_id": "EV-PDB-9BLY-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9BLY", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BLY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Composite structure of full-length human dynein-1 in phi-particle conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BLZ", "evidence_id": "EV-PDB-9BLZ-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "9BLZ", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-1(phi motor) of full-length human dynein-1 in 5mM ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BM0", "evidence_id": "EV-PDB-9BM0-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9BM0", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BM0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-2 of motor domain from full-length human dynein-1 in 5mM ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BM1", "evidence_id": "EV-PDB-9BM1-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "9BM1", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BM1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-3 of motor domain from full-length human dynein-1 in 5mM ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BM2", "evidence_id": "EV-PDB-9BM2-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "9BM2", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BM2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-4 of motor domain from full-length human dynein-1 in 5 mM ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BM3", "evidence_id": "EV-PDB-9BM3-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "9BM3", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BM3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-5a of motor domain from full-length human dynein-1 in 5 mM ATP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BM4", "evidence_id": "EV-PDB-9BM4-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "9BM4", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BM4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-5b of motor domain from full-length human dynein-1 in 5 mM ATP"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DH6", "evidence_id": "EV-PDB-9DH6-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9DH6", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DH6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-2 of the motor domain from full-length human dynein-1 in 5mM AMPPNP with 5mM Mg2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9DH5", "evidence_id": "EV-PDB-9DH5-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9DH5", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9DH5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-1 of the motor domain from full-length human dynein-1 in 5mM AMPPNP with 5mM Mg2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BN6", "evidence_id": "EV-PDB-9BN6-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "9BN6", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BN6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The alpha registry-locked dynein motor domain mutant in 5mM ATPVi condition, class2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BN1", "evidence_id": "EV-PDB-9BN1-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9BN1", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BN1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-8 of motor domain from full-length human dynein-1 in apo condition"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BN0", "evidence_id": "EV-PDB-9BN0-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "9BN0", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BN0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-7 of motor domain from full-length human dynein-1 in apo condition"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BMZ", "evidence_id": "EV-PDB-9BMZ-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.97}, "provenance": {"deposit_id": "9BMZ", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BMZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-2 of motor domain from full-length human dynein-1 in apo condition"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BMY", "evidence_id": "EV-PDB-9BMY-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.86}, "provenance": {"deposit_id": "9BMY", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BMY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-1 of motor domain from full-length human dynein-1 in apo condition"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BMW", "evidence_id": "EV-PDB-9BMW-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9BMW", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BMW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-7b-post2 of motor domain from full-length human dynein-1 in 5 mM ADP"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ADP", "ATP", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Cytoplasmic dynein 1 heavy chain 1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BMV", "evidence_id": "EV-PDB-9BMV-1", "mappings": [], "molecule_id": "Q14204", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "9BMV", "doi": "10.1038/s41594-025-01543-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BMV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "State-7a-post1 of motor domain from full-length human dynein-1 in 5 mM ADP"}
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"position": 12022, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphothreonine", "position": 30443, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphotyrosine", "position": 32341, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 33245, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 33247, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 33602, "source": "UniProtKB"}, {"kind": "ptm", "name": "Phosphoserine", "position": 33614, "source": "UniProtKB"}], "molecule_id": "Q8WZ42", "molecule_type": "protein", "name": "Titin", "organism": {"name": "Homo sapiens", "taxon_id": 9606}, "provenance": {"deposit_id": "Q8WZ42", "doi": null, "licence": "CC BY 4.0 (UniProt)", "retrieved": "2026-10-19", "source": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8WZ42/entry"}, "record_type": "molecule", "sequence": "MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQDADKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKLETVPGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVATVVAAVDQARVREPREPGHLEESYAQQTTLEYGYKERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQELQSILEQDKLTPESTREFLCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEEPETQAVLSDTEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVAEEVLSPKEKTVSDTNREQRVTLQKQEAQSALILSQSLAEGHVESLQSPDVMISQVNYEPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSDNVVMPPDQIIESKREPVAIKKVQEVQGRDLLSKESLLSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAVNITQEPRHIMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTAEGPRIQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPVTVKDQTCPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETREVSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLRMPYDVPEPRKYKQTTIEEDQRIKQFVPMSDMKWYKKIRDQYEMPGKLDRVVQKRPKRIRLSRWEQFYVMPLPRITDQYRPKWRIPKLSQDDLEIVRPARRRTPSPDYDFYYRPRRRSLGDISDEELLLPIDDYLAMKRTEEERLRLEEELELGFSASPPSRSPPHFELSSLRYSSPQAHVKVEETRKDFRYSTYHIPTKAEASTSYAELRERHAQAAYRQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELDFMSKEEKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI", "sequence_length": 34350}
{"assumptions": [], "basis": "observed", "description": "Folded Ig repeat 27 in solution, as in 1TIT (NMR, minimised average structure).", "family_label": null, "molecule_id": "Q8WZ42", "name": "folded Ig domain", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (Q8WZ42.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/Q8WZ42.yaml"}, "record_type": "state", "representative_model": "I27-folded-cif", "secondary_structure": null, "state_id": "I27-folded", "status": "draft"}
{"assumptions": ["Defined from force-extension unfolding; no observed structure exists.", "The unfolded state is treated as a single ensemble; intermediates are not resolved.", "No evidence is ingested yet; the SMASH-BIO release file is pending."], "basis": "inferred", "description": "Unfolded state reached under mechanical load. No observed structure.", "family_label": null, "molecule_id": "Q8WZ42", "name": "unfolded under force", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (Q8WZ42.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/Q8WZ42.yaml"}, "record_type": "state", "representative_model": null, "secondary_structure": null, "state_id": "I27-unfolded", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.6, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "TITIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1BPV", "evidence_id": "EV-PDB-1BPV-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1BPV", "doi": "10.1016/S0969-2126(98)00129-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1BPV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "TITIN MODULE A71 FROM HUMAN CARDIAC MUSCLE, NMR, 50 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "IMMUNOGLOBULIN-LIKE DOMAIN I1 FROM TITIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1G1C", "evidence_id": "EV-PDB-1G1C-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1G1C", "doi": "10.1016/s0969-2126(01)00591-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1G1C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "I1 DOMAIN FROM TITIN"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "TITIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NCT", "evidence_id": "EV-PDB-1NCT-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1NCT", "doi": "10.1006/jmbi.1996.0725", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NCT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "TITIN MODULE M5, N-TERMINALLY EXTENDED, NMR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.8, "salt_mM": null, "temperature_c": 26.85}, "construct": {"description": "TITIN (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1NCU", "evidence_id": "EV-PDB-1NCU-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1NCU", "doi": "10.1006/jmbi.1996.0725", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1NCU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Titin Module M5, N-terminally Extended, NMR"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TITIN, I27 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TIT", "evidence_id": "EV-PDB-1TIT-1", "mappings": [{"confidence": "high", "justification": "NMR structure of folded Ig repeat 27; representative for the folded state.", "rule": "curator_assignment", "state_id": "I27-folded", "who": "curator:draft (unreviewed)"}], "molecule_id": "Q8WZ42", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1TIT", "doi": "10.1016/S0969-2126(96)00036-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TIT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "TITIN, IG REPEAT 27, NMR, MINIMIZED AVERAGE STRUCTURE"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TITIN, I27 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TIU", "evidence_id": "EV-PDB-1TIU-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as I27 (I91); other titin domains are excluded by title.", "rule": "i27-structures-folded", "state_id": "I27-folded", "who": "rule:i27-structures-folded"}], "molecule_id": "Q8WZ42", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1TIU", "doi": "10.1016/S0969-2126(96)00036-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TIU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "TITIN, IG REPEAT 27, NMR, 24 STRUCTURES"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "TITIN MODULE M5 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1TNN", "evidence_id": "EV-PDB-1TNN-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "1TNN", "doi": "10.1016/S0969-2126(01)00170-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1TNN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WAA", "evidence_id": "EV-PDB-1WAA-3", "mappings": [{"confidence": "medium", "justification": "Structure titled as I27 (I91); other titin domains are excluded by title.", "rule": "i27-structures-folded", "state_id": "I27-folded", "who": "rule:i27-structures-folded"}], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1WAA", "doi": "10.1371/JOURNAL.PCBI.1000306", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "IG27 protein domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WAA", "evidence_id": "EV-PDB-1WAA-2", "mappings": [{"confidence": "medium", "justification": "Structure titled as I27 (I91); other titin domains are excluded by title.", "rule": "i27-structures-folded", "state_id": "I27-folded", "who": "rule:i27-structures-folded"}], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1WAA", "doi": "10.1371/JOURNAL.PCBI.1000306", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "IG27 protein domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1WAA", "evidence_id": "EV-PDB-1WAA-1", "mappings": [{"confidence": "medium", "justification": "Structure titled as I27 (I91); other titin domains are excluded by title.", "rule": "i27-structures-folded", "state_id": "I27-folded", "who": "rule:i27-structures-folded"}], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.8}, "provenance": {"deposit_id": "1WAA", "doi": "10.1371/JOURNAL.PCBI.1000306", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1WAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "IG27 protein domain"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.45, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "N2B-TITIN ISOFORM (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/1YA5", "evidence_id": "EV-PDB-1YA5-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.445}, "provenance": {"deposit_id": "1YA5", "doi": "10.1038/nature04343", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/1YA5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the titin domains z1z2 in complex with telethonin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Titin (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2A38", "evidence_id": "EV-PDB-2A38-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.0}, "provenance": {"deposit_id": "2A38", "doi": "10.1016/j.str.2006.07.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2A38"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the N-Terminus of titin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN HEART ISOFORM N2-B (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2BK8", "evidence_id": "EV-PDB-2BK8-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.69}, "provenance": {"deposit_id": "2BK8", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2BK8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "M1 domain from titin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.45, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "N2B-Titin Isoform (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2F8V", "evidence_id": "EV-PDB-2F8V-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "2F8V", "doi": "10.1016/j.jsb.2006.03.028", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2F8V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of full length telethonin in complex with the N-terminus of titin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Titin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2ILL", "evidence_id": "EV-PDB-2ILL-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "2ILL", "doi": "10.1107/S0907444906055624", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2ILL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Anomalous substructure of Titin-A168169"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2J8H", "evidence_id": "EV-PDB-2J8H-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.99}, "provenance": {"deposit_id": "2J8H", "doi": "10.1016/J.JMB.2007.05.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2J8H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the immunoglobulin tandem repeat A168-A169 of titin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 9.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2J8O", "evidence_id": "EV-PDB-2J8O-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.49}, "provenance": {"deposit_id": "2J8O", "doi": "10.1016/J.JMB.2007.05.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2J8O"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the immunoglobulin tandem repeat of titin A168-A169"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Titin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2NZI", "evidence_id": "EV-PDB-2NZI-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "2NZI", "doi": "10.1096/fj.06-7644com", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2NZI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of domains A168-A170 from titin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains T)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WP3", "evidence_id": "EV-PDB-2WP3-2", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.48}, "provenance": {"deposit_id": "2WP3", "doi": "10.1073/PNAS.0913736107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WP3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Titin M10-Obscurin like 1 Ig complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GOL", "SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains T)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WWK", "evidence_id": "EV-PDB-2WWK-2", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.7}, "provenance": {"deposit_id": "2WWK", "doi": "10.1073/PNAS.0913736107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WWK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Titin M10-Obscurin like 1 Ig F17R mutant complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "TITIN (chains D,T)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/2WWM", "evidence_id": "EV-PDB-2WWM-2", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "2WWM", "doi": "10.1073/PNAS.0913736107", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/2WWM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the Titin M10-Obscurin like 1 Ig complex in space group P1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Titin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3B43", "evidence_id": "EV-PDB-3B43-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "3B43", "doi": "10.1073/pnas.0707163105", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3B43"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "I-band fragment I65-I70 from titin"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["SO4"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Titin (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3KNB", "evidence_id": "EV-PDB-3KNB-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.4}, "provenance": {"deposit_id": "3KNB", "doi": "10.1038/embor.2010.65", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3KNB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the titin C-terminus in complex with obscurin-like 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MPD", "MRD"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "A77-A78 domain from Titin (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/3LPW", "evidence_id": "EV-PDB-3LPW-1", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.65}, "provenance": {"deposit_id": "3LPW", "doi": "10.1016/j.jmb.2010.06.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/3LPW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the FnIII-tandem A77-A78 from the A-band of titin"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 3.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Obscurin (chains 1,3,5,7,9,B,D,F,H,J,L,N,P,R,T,V,X,Z)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4UOW", "evidence_id": "EV-PDB-4UOW-2", "mappings": [], "molecule_id": "Q8WZ42", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "4UOW", "doi": "10.1016/J.JMB.2014.11.019", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4UOW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the titin M10-Obscurin Ig domain 1 complex"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4ZT9", "evidence_id": "EV-PDB-4ZT9-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "4ZT9", "doi": "10.1126/science.aab1452", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4ZT9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Nuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolution"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6IFO", "evidence_id": "EV-PDB-6IFO-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.313}, "provenance": {"deposit_id": "6IFO", "doi": "10.1016/j.molcel.2018.11.011", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6IFO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of AcrIIA2-SpyCas9-sgRNA ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -188.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6K4S", "evidence_id": "EV-PDB-6K4S-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "6K4S", "doi": "10.1371/journal.pbio.3000496", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6K4S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of xCas9 in complex with sgRNA and DNA (TGC PAM)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQX", "evidence_id": "EV-PDB-7QQX-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7QQX", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to FANCF off-target5 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQW", "evidence_id": "EV-PDB-7QQW-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7QQW", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to FANCF off-target4 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQV", "evidence_id": "EV-PDB-7QQV-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "7QQV", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to FANCF off-target3 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQU", "evidence_id": "EV-PDB-7QQU-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "7QQU", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to FANCF off-target2 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQT", "evidence_id": "EV-PDB-7QQT-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "7QQT", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to FANCF off-target1 DNA substrate"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQQ", "evidence_id": "EV-PDB-7QQQ-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.65}, "provenance": {"deposit_id": "7QQQ", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to AAVS1 off-target4 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQP", "evidence_id": "EV-PDB-7QQP-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7QQP", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to AAVS1 off-target3 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QQO", "evidence_id": "EV-PDB-7QQO-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7QQO", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QQO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to AAVS1 off-target1 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OXA", "evidence_id": "EV-PDB-7OXA-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "7OXA", "doi": "10.1016/j.molcel.2021.07.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OXA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Target-bound SpCas9 complex with AAVS1 chimeric RNA-DNA guide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OX9", "evidence_id": "EV-PDB-7OX9-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "7OX9", "doi": "10.1016/j.molcel.2021.07.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Target-bound SpCas9 complex with AAVS1 all-RNA guide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OX8", "evidence_id": "EV-PDB-7OX8-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "7OX8", "doi": "10.1016/j.molcel.2021.07.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OX8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Target-bound SpCas9 complex with TRAC full RNA guide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7OX7", "evidence_id": "EV-PDB-7OX7-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "7OX7", "doi": "10.1016/j.molcel.2021.07.035", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7OX7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Target-bound SpCas9 complex with TRAC chimeric RNA-DNA guide"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6VPC", "evidence_id": "EV-PDB-6VPC-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "6VPC", "doi": "10.1126/science.abb1390", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6VPC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SpCas9 DNA adenine base editor - ABE8e"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O56", "evidence_id": "EV-PDB-6O56-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 1.9}, "provenance": {"deposit_id": "6O56", "doi": "10.1021/jacs.9b10521", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O56"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "HNH Nuclease from S. pyogenes Cas9"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O0Z", "evidence_id": "EV-PDB-6O0Z-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "6O0Z", "doi": "10.1038/s41594-019-0258-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O0Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O0Y", "evidence_id": "EV-PDB-6O0Y-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.37}, "provenance": {"deposit_id": "6O0Y", "doi": "10.1038/s41594-019-0258-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O0Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6O0X", "evidence_id": "EV-PDB-6O0X-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.28}, "provenance": {"deposit_id": "6O0X", "doi": "10.1038/s41594-019-0258-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6O0X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZO1", "evidence_id": "EV-PDB-7ZO1-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.4}, "provenance": {"deposit_id": "7ZO1", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZO1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to CD34 off-target9 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8KAG", "evidence_id": "EV-PDB-8KAG-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.88}, "provenance": {"deposit_id": "8KAG", "doi": "10.1038/s41587-024-02255-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8KAG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SpyCas9 in complex with sgRNA and target RNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8KAM", "evidence_id": "EV-PDB-8KAM-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.91}, "provenance": {"deposit_id": "8KAM", "doi": "10.1038/s41587-024-02255-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8KAM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SRS", "evidence_id": "EV-PDB-8SRS-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "8SRS", "doi": "10.1038/s41467-024-47830-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SRS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpRY-Cas9:gRNA complex targeting TAC PAM DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T6X", "evidence_id": "EV-PDB-8T6X-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "8T6X", "doi": "10.1038/s41467-024-47830-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T6X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loop"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TZZ", "evidence_id": "EV-PDB-8TZZ-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "8TZZ", "doi": "10.1038/s41467-024-47830-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TZZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpG Cas9 with NGC PAM DNA target"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8T7S", "evidence_id": "EV-PDB-8T7S-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.01}, "provenance": {"deposit_id": "8T7S", "doi": "10.1038/s41467-024-47830-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8T7S"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpRYmer bound to NAC PAM DNA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8G1I", "evidence_id": "EV-PDB-8G1I-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "8G1I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8G1I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with sgRNA and target DNA"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FZT", "evidence_id": "EV-PDB-8FZT-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "8FZT", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FZT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with dual-guide RNA and target DNA"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z4J", "evidence_id": "EV-PDB-7Z4J-5", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "7Z4J", "doi": "10.1038/s41586-022-05114-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z4J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z4I", "evidence_id": "EV-PDB-7Z4I-4", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.12}, "provenance": {"deposit_id": "7Z4I", "doi": "10.1038/s41586-022-05114-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z4I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 bound to 16-nucleotide complementary DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z4H", "evidence_id": "EV-PDB-7Z4H-4", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.49}, "provenance": {"deposit_id": "7Z4H", "doi": "10.1038/s41586-022-05114-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z4H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 bound to 14-nucleotide complementary DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z4G", "evidence_id": "EV-PDB-7Z4G-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.64}, "provenance": {"deposit_id": "7Z4G", "doi": "10.1038/s41586-022-05114-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z4G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 bound to 12-nucleotide complementary DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z4E", "evidence_id": "EV-PDB-7Z4E-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.14}, "provenance": {"deposit_id": "7Z4E", "doi": "10.1038/s41586-022-05114-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z4E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 bound to 8-nucleotide complementary DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B,E)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z4D", "evidence_id": "EV-PDB-7Z4D-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7Z4D", "doi": "10.1038/s41586-022-05114-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z4D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Z4C", "evidence_id": "EV-PDB-7Z4C-4", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.87}, "provenance": {"deposit_id": "7Z4C", "doi": "10.1038/s41586-022-05114-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Z4C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 bound to 6 nucleotide complementary DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VK9", "evidence_id": "EV-PDB-7VK9-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7VK9", "doi": "10.1021/acscatal.2c01804", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VK9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of xCas9 P411T"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S4X", "evidence_id": "EV-PDB-7S4X-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "7S4X", "doi": "10.1038/s41586-022-04470-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S4X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S4V", "evidence_id": "EV-PDB-7S4V-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.28}, "provenance": {"deposit_id": "7S4V", "doi": "10.1038/s41586-022-04470-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S4V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S4U", "evidence_id": "EV-PDB-7S4U-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.56}, "provenance": {"deposit_id": "7S4U", "doi": "10.1038/s41586-022-04470-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S4U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-point"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S38", "evidence_id": "EV-PDB-7S38-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7S38", "doi": "10.1038/s41594-022-00756-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S38"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cas9:sgRNA:DNA (S. pyogenes) forming a 3-base-pair R-loop"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S37", "evidence_id": "EV-PDB-7S37-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7S37", "doi": "10.1038/s41594-022-00756-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S37"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cas9:sgRNA (S. pyogenes) in the open-protein conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7S36", "evidence_id": "EV-PDB-7S36-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7S36", "doi": "10.1038/s41594-022-00756-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7S36"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, closed-protein/bent-DNA conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QR8", "evidence_id": "EV-PDB-7QR8-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.75}, "provenance": {"deposit_id": "7QR8", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QR8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to PTPRC off-target1 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["K", "MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7QR0", "evidence_id": "EV-PDB-7QR0-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "7QR0", "doi": "10.1016/j.cell.2022.09.026", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7QR0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SpCas9 bound to TRAC off-target1 DNA substrate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8U3Y", "evidence_id": "EV-PDB-8U3Y-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8U3Y", "doi": "10.1038/s41467-024-47830-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8U3Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpG Cas9 with NGG PAM DNA target"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WUS", "evidence_id": "EV-PDB-8WUS-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8WUS", "doi": "10.1038/s41586-024-07497-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WUS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9-MMLV RT-pegRNA-target DNA complex (termination)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WUV", "evidence_id": "EV-PDB-8WUV-3", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8WUV", "doi": "10.1038/s41586-024-07497-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WUV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9CGU", "evidence_id": "EV-PDB-9CGU-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9CGU", "doi": "10.1093/nar/gkae1164", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9CGU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cas9 ternary complex, 14-nt sgRNA, State II (kinked)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EAK", "evidence_id": "EV-PDB-9EAK-4", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "9EAK", "doi": "10.1038/s41467-025-60668-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EAK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State I - pre-activation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EAL", "evidence_id": "EV-PDB-9EAL-4", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "9EAL", "doi": "10.1038/s41467-025-60668-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EAL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State II - precleavage)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ED9", "evidence_id": "EV-PDB-9ED9-5", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "9ED9", "doi": "10.1038/s41467-025-60668-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ED9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State III - checkpoint)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EDA", "evidence_id": "EV-PDB-9EDA-5", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.88}, "provenance": {"deposit_id": "9EDA", "doi": "10.1038/s41467-025-60668-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EDA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State IV - product)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9H4L", "evidence_id": "EV-PDB-9H4L-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "9H4L", "doi": "10.1038/s41586-026-10255-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9H4L"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "dCas9 bound to off-target 2 EMX1-1 (-)SC DNA minicircle"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9H4M", "evidence_id": "EV-PDB-9H4M-4", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "9H4M", "doi": "10.1038/s41586-026-10255-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9H4M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "wtCas9 bound to off-target 1 EMX1-1 (-)SC DNA minicircle"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JL4", "evidence_id": "EV-PDB-9JL4-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "9JL4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JL4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Apo-spCas9 conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K4C", "evidence_id": "EV-PDB-9K4C-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "9K4C", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K4C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 22nt sgRNA - DNA ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K4E", "evidence_id": "EV-PDB-9K4E-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9K4E", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K4E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - mismatch 22nt sgRNA - DNA ternary complex class1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LKJ", "evidence_id": "EV-PDB-9LKJ-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "9LKJ", "doi": "10.1038/s41594-025-01741-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LKJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Cas9-sgRNA-A27"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W7T", "evidence_id": "EV-PDB-9W7T-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.91}, "provenance": {"deposit_id": "9W7T", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W7T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W7U", "evidence_id": "EV-PDB-9W7U-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.83}, "provenance": {"deposit_id": "9W7U", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W7U"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W7V", "evidence_id": "EV-PDB-9W7V-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.81}, "provenance": {"deposit_id": "9W7V", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W7V"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class D"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WDX", "evidence_id": "EV-PDB-9WDX-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.72}, "provenance": {"deposit_id": "9WDX", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WDX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SpCas9 with engineered disulfide bonds (R1210C/V1280C and L1119C/P1128C)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9ZQ6", "evidence_id": "EV-PDB-9ZQ6-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "9ZQ6", "doi": "10.1042/BCJ20250364", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9ZQ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SpyCas9 in complex with the anti-CRISPR protein AcrIIA26"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WAW", "evidence_id": "EV-PDB-9WAW-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "9WAW", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WAW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class E"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WAA", "evidence_id": "EV-PDB-9WAA-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.17}, "provenance": {"deposit_id": "9WAA", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WAA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 22nt sgRNA - DNA ternary complex Class C"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9WA9", "evidence_id": "EV-PDB-9WA9-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.12}, "provenance": {"deposit_id": "9WA9", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9WA9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 22nt sgRNA - DNA ternary complex Class B"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W9D", "evidence_id": "EV-PDB-9W9D-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.4}, "provenance": {"deposit_id": "9W9D", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W9D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 22nt sgRNA - DNA ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9W7Q", "evidence_id": "EV-PDB-9W7Q-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.79}, "provenance": {"deposit_id": "9W7Q", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9W7Q"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class A"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KJ6", "evidence_id": "EV-PDB-9KJ6-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.59}, "provenance": {"deposit_id": "9KJ6", "doi": "10.1038/s41598-025-25367-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KJ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal Structure of SpCas9 ternary complex, amino acids (1242-1263) replaced with Gly-Ser linker"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K4F", "evidence_id": "EV-PDB-9K4F-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.27}, "provenance": {"deposit_id": "9K4F", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K4F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - mismatch 22nt sgRNA - DNA ternary complex class2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9K4D", "evidence_id": "EV-PDB-9K4D-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "9K4D", "doi": "10.1038/s41594-026-01753-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9K4D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SuperFi Cas9 - 20nt sgRNA - DNA ternary complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JL2", "evidence_id": "EV-PDB-9JL2-3", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "9JL2", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JL2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Classical conformation for the spCas9 with gRNA and target DNA complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JL1", "evidence_id": "EV-PDB-9JL1-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "9JL1", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JL1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with mini-gRNA conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9H4K", "evidence_id": "EV-PDB-9H4K-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9H4K", "doi": "10.1038/s41586-026-10255-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9H4K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "dCas9 bound to off-target 1 EMX1-1 (-)SC DNA minicircle"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9H4J", "evidence_id": "EV-PDB-9H4J-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9H4J", "doi": "10.1038/s41586-026-10255-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9H4J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "dCas9 bound to on-target EMX1-1 (-)SC DNA minicircle"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9EDB", "evidence_id": "EV-PDB-9EDB-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9EDB", "doi": "10.1038/s41467-025-60668-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9EDB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State V - dissociated)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9C9P", "evidence_id": "EV-PDB-9C9P-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "9C9P", "doi": "10.1093/nar/gkae1164", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9C9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cas9 ternary complex, 14-nt sgRNA, State I (linear)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains P)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9B2K", "evidence_id": "EV-PDB-9B2K-3", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.67}, "provenance": {"deposit_id": "9B2K", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9B2K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9 with dual-guide RNA in open conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains X)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YNY", "evidence_id": "EV-PDB-8YNY-9", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.52}, "provenance": {"deposit_id": "8YNY", "doi": "10.1038/s41467-024-54768-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YNY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of Cas9-sgRNA ribonucleoprotein bound to nucleosome"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YGJ", "evidence_id": "EV-PDB-8YGJ-6", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8YGJ", "doi": "10.1038/s41586-024-07497-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YGJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 28-nt)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YE9", "evidence_id": "EV-PDB-8YE9-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.43}, "provenance": {"deposit_id": "8YE9", "doi": "10.1007/s11427-024-2607-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YE9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Cas9-sgRNA-A25 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YE6", "evidence_id": "EV-PDB-8YE6-2", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "8YE6", "doi": "10.1007/s11427-024-2607-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YE6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Cas9-sgRNA-A32 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "CRISPR-associated endonuclease Cas9/Csn1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WUU", "evidence_id": "EV-PDB-8WUU-1", "mappings": [], "molecule_id": "Q99ZW2", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8WUU", "doi": "10.1038/s41586-024-07497-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WUU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SpCas9-pegRNA-target DNA complex (pre-initiation)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7DX9", "evidence_id": "EV-PDB-7DX9-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "7DX9", "doi": "10.1038/s41422-021-00490-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7DX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 3 (3 up RBD and 2 PD bound)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7EFP", "evidence_id": "EV-PDB-7EFP-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.698}, "provenance": {"deposit_id": "7EFP", "doi": "10.1038/s41392-021-00756-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7EFP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (S19W,N330Y)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7KNH", "evidence_id": "EV-PDB-7KNH-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.74}, "provenance": {"deposit_id": "7KNH", "doi": "10.1016/j.chom.2020.11.004", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7KNH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM Structure of Double ACE2-Bound SARS-CoV-2 Trimer Spike at pH 5.5"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NA", "NAG", "PG4", "PG5", "PGE", "SO4", "ZN", "branched: alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains E,F)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7L0N", "evidence_id": "EV-PDB-7L0N-5", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "7L0N", "doi": "10.1016/j.cell.2021.01.037", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7L0N"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7LO4", "evidence_id": "EV-PDB-7LO4-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.465}, "provenance": {"deposit_id": "7LO4", "doi": "10.1101/2021.03.16.434488", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7LO4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 spike receptor-binding domain with a G485R mutation in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7MJN", "evidence_id": "EV-PDB-7MJN-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "7MJN", "doi": "10.1371/journal.pbio.3001237", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7MJN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7NXC", "evidence_id": "EV-PDB-7NXC-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7NXC", "doi": "10.1016/j.cell.2021.03.055", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7NXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 P.1 variant Spike glycoprotein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P19", "evidence_id": "EV-PDB-7P19-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "7P19", "doi": "10.1107/S2059798322007677", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P19"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 RBD Q498Y complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 2.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + NMR restraints", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P55", "evidence_id": "EV-PDB-7P55-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "structure", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "7P55", "doi": "10.1016/j.heliyon.2022.e11568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P55"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_structure", "title": "NMR structure of human ACE2 21-42 fragment in HFIP/water 50/50 v/v"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P8I", "evidence_id": "EV-PDB-7P8I-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.5}, "provenance": {"deposit_id": "7P8I", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P8I"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.9, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7P8J", "evidence_id": "EV-PDB-7P8J-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.585}, "provenance": {"deposit_id": "7P8J", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7P8J"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R10", "evidence_id": "EV-PDB-7R10-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7R10", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R10"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R11", "evidence_id": "EV-PDB-7R11-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "7R11", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R11"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of Beta Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R12", "evidence_id": "EV-PDB-7R12-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7R12", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R12"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Dissociated S1 domain of Mink Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7R1A", "evidence_id": "EV-PDB-7R1A-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "7R1A", "doi": "10.1038/s41467-022-28768-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7R1A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Furin Cleaved Alpha Variant SARS-CoV-2 Spike in complex with 3 ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 6.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B,C,D)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7RPV", "evidence_id": "EV-PDB-7RPV-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.54}, "provenance": {"deposit_id": "7RPV", "doi": "10.1101/2021.11.24.469776", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7RPV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of affinity-enhancing and catalytically inactive ACE2 in complex with SARS-CoV-2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.5, "salt_mM": null, "temperature_c": -193.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SN0", "evidence_id": "EV-PDB-7SN0-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "7SN0", "doi": "10.1126/science.abl6251", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SN0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of spike protein receptor binding domain of escape mutant SARS-CoV-2 from immunocompromised patient (d146*) in complex with human receptor ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXX", "evidence_id": "EV-PDB-7SXX-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "7SXX", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXY", "evidence_id": "EV-PDB-7SXY-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "7SXY", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SXZ", "evidence_id": "EV-PDB-7SXZ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "7SXZ", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SXZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,L452R mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY0", "evidence_id": "EV-PDB-7SY0-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7SY0", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,L452R mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY1", "evidence_id": "EV-PDB-7SY1-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "7SY1", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY2", "evidence_id": "EV-PDB-7SY2-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "7SY2", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY3", "evidence_id": "EV-PDB-7SY3-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.95}, "provenance": {"deposit_id": "7SY3", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY4", "evidence_id": "EV-PDB-7SY4-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.35}, "provenance": {"deposit_id": "7SY4", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY5", "evidence_id": "EV-PDB-7SY5-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.59}, "provenance": {"deposit_id": "7SY5", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY6", "evidence_id": "EV-PDB-7SY6-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "7SY6", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY7", "evidence_id": "EV-PDB-7SY7-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.81}, "provenance": {"deposit_id": "7SY7", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7SY8", "evidence_id": "EV-PDB-7SY8-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7SY8", "doi": "10.1016/j.celrep.2021.110156", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7SY8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7T9K", "evidence_id": "EV-PDB-7T9K-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.45}, "provenance": {"deposit_id": "7T9K", "doi": "10.1126/science.abn7760", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7T9K"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron spike protein in complex with human ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VX5", "evidence_id": "EV-PDB-7VX5-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7VX5", "doi": "10.1038/s41467-021-27350-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ACE2-RBD in SARS-CoV-2 Kappa variant S-ACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7VX9", "evidence_id": "EV-PDB-7VX9-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.0}, "provenance": {"deposit_id": "7VX9", "doi": "10.1038/s41467-021-27350-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7VX9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Kappa variant spike protein in complex wth ACE2, state C1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2,Green fluorescent protein (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V81", "evidence_id": "EV-PDB-7V81-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7V81", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V81"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2,Green fluorescent protein (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7V7Z", "evidence_id": "EV-PDB-7V7Z-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7V7Z", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7V7Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-Beta variant (B.1.351) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7UFL", "evidence_id": "EV-PDB-7UFL-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.84}, "provenance": {"deposit_id": "7UFL", "doi": "10.1073/pnas.2206509119", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7UFL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric omicron RBD (strain BA.2) complexed with chimeric mouse ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPB", "evidence_id": "EV-PDB-7WPB-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "7WPB", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPB"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron Variant RBD complexed with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WPC", "evidence_id": "EV-PDB-7WPC-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "7WPC", "doi": "10.1126/science.abn8863", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WPC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The second RBD of SARS-CoV-2 Omicron Variant in complexed with RBD-ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WSA", "evidence_id": "EV-PDB-7WSA-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7WSA", "doi": "10.1016/j.celrep.2022.110770", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WSA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WVP", "evidence_id": "EV-PDB-7WVP-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "7WVP", "doi": "10.1038/s41586-022-04581-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WVP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C2 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7WVQ", "evidence_id": "EV-PDB-7WVQ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.04}, "provenance": {"deposit_id": "7WVQ", "doi": "10.1038/s41586-022-04581-9", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7WVQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron Spike protein with human ACE2 receptor, C3 state"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XAZ", "evidence_id": "EV-PDB-7XAZ-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7XAZ", "doi": "10.1016/j.cell.2022.06.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XAZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Omicron BA.1.1 RBD complexed with hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XB0", "evidence_id": "EV-PDB-7XB0-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "7XB0", "doi": "10.1016/j.cell.2022.06.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XB0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Omicron BA.2 RBD complexed with hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XB1", "evidence_id": "EV-PDB-7XB1-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "7XB1", "doi": "10.1016/j.cell.2022.06.023", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XB1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of Omicron BA.3 RBD complexed with hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XBF", "evidence_id": "EV-PDB-7XBF-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.51}, "provenance": {"deposit_id": "7XBF", "doi": "10.15252/embj.2022111737", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XBF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The complex structure of RshSTT182/200 RBD-insert2 bound to human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XBG", "evidence_id": "EV-PDB-7XBG-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.37}, "provenance": {"deposit_id": "7XBG", "doi": "10.15252/embj.2022111737", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XBG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The crystal structure of RshSTT182/200 RBD-insert2-T346R-Y496G mutant in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XBH", "evidence_id": "EV-PDB-7XBH-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.02}, "provenance": {"deposit_id": "7XBH", "doi": "10.15252/embj.2022111737", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XBH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The complex structure of RshSTT182/200 RBD bound to human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XCH", "evidence_id": "EV-PDB-7XCH-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7XCH", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XCH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (two-RBD-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XCI", "evidence_id": "EV-PDB-7XCI-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7XCI", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XCI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with human ACE2 ectodomain (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XCP", "evidence_id": "EV-PDB-7XCP-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "7XCP", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XCP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XID", "evidence_id": "EV-PDB-7XID-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7XID", "doi": "10.1016/j.isci.2022.104431", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XID"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XO7", "evidence_id": "EV-PDB-7XO7-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "7XO7", "doi": "10.1038/s41422-022-00672-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XO7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two human ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XO8", "evidence_id": "EV-PDB-7XO8-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.48}, "provenance": {"deposit_id": "7XO8", "doi": "10.1038/s41422-022-00672-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XO8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three human ACE2 Bound"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XO9", "evidence_id": "EV-PDB-7XO9-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "7XO9", "doi": "10.1038/s41422-022-00672-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XO9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.2 Variant RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7XWA", "evidence_id": "EV-PDB-7XWA-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "7XWA", "doi": "10.1016/j.cell.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7XWA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BA.4/5 variant spike protein in complex with its receptor ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y1Y", "evidence_id": "EV-PDB-7Y1Y-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7Y1Y", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y1Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.2) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y1Z", "evidence_id": "EV-PDB-7Y1Z-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "7Y1Z", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y1Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.3) in complex with three PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y20", "evidence_id": "EV-PDB-7Y20-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.8}, "provenance": {"deposit_id": "7Y20", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y20"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.3) in complex with two PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,F,H)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y21", "evidence_id": "EV-PDB-7Y21-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "7Y21", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y21"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.5) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3PH", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y75", "evidence_id": "EV-PDB-7Y75-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7Y75", "doi": "10.1038/s41421-022-00488-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y75"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SIT1-ACE2-BA.2 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["3PH", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y76", "evidence_id": "EV-PDB-7Y76-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7Y76", "doi": "10.1038/s41421-022-00488-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y76"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SIT1-ACE2-BA.5 RBD"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7Y9Z", "evidence_id": "EV-PDB-7Y9Z-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "7Y9Z", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7Y9Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (one-RBD-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YA0", "evidence_id": "EV-PDB-7YA0-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "7YA0", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YA0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (S-6P-RRAR)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YA1", "evidence_id": "EV-PDB-7YA1-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "7YA1", "doi": "10.1038/s41467-022-32665-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YA1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YDI", "evidence_id": "EV-PDB-7YDI-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.98}, "provenance": {"deposit_id": "7YDI", "doi": "10.1038/s41564-022-01235-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YDI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains E,J,M)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YEG", "evidence_id": "EV-PDB-7YEG-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "7YEG", "doi": "10.1038/s41564-022-01235-4", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YEG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YHW", "evidence_id": "EV-PDB-7YHW-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.09}, "provenance": {"deposit_id": "7YHW", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YHW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YJ3", "evidence_id": "EV-PDB-7YJ3-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "7YJ3", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YJ3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YR2", "evidence_id": "EV-PDB-7YR2-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "7YR2", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YR2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state1)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YR3", "evidence_id": "EV-PDB-7YR3-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.52}, "provenance": {"deposit_id": "7YR3", "doi": "10.1016/j.chom.2022.09.018", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YR3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7YR4", "evidence_id": "EV-PDB-7YR4-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.12}, "provenance": {"deposit_id": "7YR4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7YR4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(interface)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZDQ", "evidence_id": "EV-PDB-7ZDQ-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "7ZDQ", "doi": "10.1371/journal.ppat.1010733", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZDQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/7ZF7", "evidence_id": "EV-PDB-7ZF7-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "7ZF7", "doi": "10.1016/j.cell.2022.05.014", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/7ZF7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron BA.2 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8AQS", "evidence_id": "EV-PDB-8AQS-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "8AQS", "doi": "10.1371/journal.ppat.1011206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8AQS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.4/5 SARS-CoV-2 Spike bound to human ACE2 (local)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "PGE"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8ASY", "evidence_id": "EV-PDB-8ASY-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.85}, "provenance": {"deposit_id": "8ASY", "doi": "10.1016/j.celrep.2022.111903", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8ASY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "SARS-CoV-2 Omicron BA.2.75 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LFI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8B9P", "evidence_id": "EV-PDB-8B9P-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.11}, "provenance": {"deposit_id": "8B9P", "doi": "10.1021/acs.jmedchem.3c00710", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8B9P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ACE2 in complex with bicyclic peptide inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LFI"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.6, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BFW", "evidence_id": "EV-PDB-8BFW-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.33}, "provenance": {"deposit_id": "8BFW", "doi": "10.1021/acs.jmedchem.3c00710", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BFW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structures of Ace2 in complex with bicyclic peptide inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LFI", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BN1", "evidence_id": "EV-PDB-8BN1-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "8BN1", "doi": "10.1021/acs.jmedchem.3c00710", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BN1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structures of Ace2 in complex with bicyclic peptide inhibitor"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["LFI", "NA", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8BYJ", "evidence_id": "EV-PDB-8BYJ-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.07}, "provenance": {"deposit_id": "8BYJ", "doi": "10.1021/acs.jmedchem.3c00710", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8BYJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "The structures of Ace2 in complex with bicyclic peptide inhibitor"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLJ", "evidence_id": "EV-PDB-8DLJ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "8DLJ", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Alpha (B.1.1.7) spike protein in complex with human ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLM", "evidence_id": "EV-PDB-8DLM-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "8DLM", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with human ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLU", "evidence_id": "EV-PDB-8DLU-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "8DLU", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DLV", "evidence_id": "EV-PDB-8DLV-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.11}, "provenance": {"deposit_id": "8DLV", "doi": "10.1038/s41467-022-32262-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DLV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM6", "evidence_id": "EV-PDB-8DM6-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8DM6", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DV2", "evidence_id": "EV-PDB-8DV2-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8DV2", "doi": "10.1016/j.str.2023.01.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DV2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to computationally engineered ACE2 mimetic CVD293"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8FXC", "evidence_id": "EV-PDB-8FXC-3", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8FXC", "doi": "10.1038/s41586-023-06487-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8FXC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HRK", "evidence_id": "EV-PDB-8HRK-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8HRK", "doi": "10.1038/s41467-024-51696-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HRK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta S-RBD-ACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HRL", "evidence_id": "EV-PDB-8HRL-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8HRL", "doi": "10.1038/s41467-024-51696-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HRL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Delta S-RBD-ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HRN", "evidence_id": "EV-PDB-8HRN-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8HRN", "doi": "10.1038/s41467-024-51696-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HRN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "PRO", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I91", "evidence_id": "EV-PDB-8I91-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8I91", "doi": "10.1038/s41421-023-00596-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I91"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ACE2-SIT1 complex bound with proline"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["GLN", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I92", "evidence_id": "EV-PDB-8I92-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8I92", "doi": "10.1038/s41421-023-00596-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I92"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ACE2-B0AT1 complex bound with glutamine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["MET", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I93", "evidence_id": "EV-PDB-8I93-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8I93", "doi": "10.1038/s41421-023-00596-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I93"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "ACE2-B0AT1 complex bound with methionine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9B", "evidence_id": "EV-PDB-8I9B-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8I9B", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BA.2.75) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9C", "evidence_id": "EV-PDB-8I9C-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.85}, "provenance": {"deposit_id": "8I9C", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9C"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron BF.7) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9D", "evidence_id": "EV-PDB-8I9D-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.95}, "provenance": {"deposit_id": "8I9D", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9D"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-ECD (Omicron XBB.1) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9E", "evidence_id": "EV-PDB-8I9E-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8I9E", "doi": "10.3390/v15061398", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9E"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-RBD(Omicron BA.3) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9F", "evidence_id": "EV-PDB-8I9F-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8I9F", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9F"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-RBD (Omicron BA.2.75) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9G", "evidence_id": "EV-PDB-8I9G-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8I9G", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-RBD (Omicron BF.7) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8I9H", "evidence_id": "EV-PDB-8I9H-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.6}, "provenance": {"deposit_id": "8I9H", "doi": "10.1038/s41421-023-00607-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8I9H"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "S-RBD (Omicron XBB.1) in complex with PD of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IOU", "evidence_id": "EV-PDB-8IOU-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "8IOU", "doi": "10.1038/s41467-023-38435-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1 spike glycoprotein in complex with ACE2 (1-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8IOV", "evidence_id": "EV-PDB-8IOV-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "8IOV", "doi": "10.1038/s41467-023-38435-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8IOV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1 spike RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JWH", "evidence_id": "EV-PDB-8JWH-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34}, "provenance": {"deposit_id": "8JWH", "doi": "10.1038/s41592-024-02247-0", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JWH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of apo-state huamn angiotensin-converting enzyme 2 (ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYO", "evidence_id": "EV-PDB-8JYO-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8JYO", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (2-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYP", "evidence_id": "EV-PDB-8JYP-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.38}, "provenance": {"deposit_id": "8JYP", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1.5 spike RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "NDG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P2Y", "evidence_id": "EV-PDB-8P2Y-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.46}, "provenance": {"deposit_id": "8P2Y", "doi": "10.1038/s41467-024-48921-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P2Y"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SIT1:ACE2 complex (closed PD conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "YCP"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P2Z", "evidence_id": "EV-PDB-8P2Z-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.5}, "provenance": {"deposit_id": "8P2Z", "doi": "10.1038/s41467-024-48921-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P2Z"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SIT1 bound to L-pipecolate (focussed map / refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8QSQ", "evidence_id": "EV-PDB-8QSQ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.7}, "provenance": {"deposit_id": "8QSQ", "doi": "10.1016/j.xcrm.2024.101553", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8QSQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Locally refined SARS-CoV-2 BA-2.86 Spike receptor binding domain (RBD) complexed with angiotensin converting enzyme 2 (ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8S9G", "evidence_id": "EV-PDB-8S9G-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8S9G", "doi": "10.1038/s41586-023-06487-6", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8S9G"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SPH", "evidence_id": "EV-PDB-8SPH-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "8SPH", "doi": "10.1128/jvi.00822-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SPH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric omicron RBD (strain XBB.1) complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 8.2, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8SPI", "evidence_id": "EV-PDB-8SPI-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "8SPI", "doi": "10.1128/jvi.00822-23", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8SPI"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric omicron RBD (strain XBB.1.5) complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TOQ", "evidence_id": "EV-PDB-8TOQ-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "8TOQ", "doi": "10.1021/acschembio.3c00568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TOQ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ACE2-peptide 1 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TOR", "evidence_id": "EV-PDB-8TOR-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "8TOR", "doi": "10.1021/acschembio.3c00568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TOR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ACE2-peptide 2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "GOL", "NAG", "ZN", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 4.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TOS", "evidence_id": "EV-PDB-8TOS-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.35}, "provenance": {"deposit_id": "8TOS", "doi": "10.1021/acschembio.3c00568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TOS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ACE2-peptide 6 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 5.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TOT", "evidence_id": "EV-PDB-8TOT-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8TOT", "doi": "10.1021/acschembio.3c00568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TOT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ACE2-peptide2 complex crystal form 2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8TOU", "evidence_id": "EV-PDB-8TOU-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.1}, "provenance": {"deposit_id": "8TOU", "doi": "10.1021/acschembio.3c00568", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8TOU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ACE2-peptide 2 complex crystal form 3"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "NDG", "YCP", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P31", "evidence_id": "EV-PDB-8P31-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.24}, "provenance": {"deposit_id": "8P31", "doi": "10.1038/s41467-024-48921-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P31"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "NDG", "YCP", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P30", "evidence_id": "EV-PDB-8P30-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "8P30", "doi": "10.1038/s41467-024-48921-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P30"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "NDG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P2X", "evidence_id": "EV-PDB-8P2X-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.59}, "provenance": {"deposit_id": "8P2X", "doi": "10.1038/s41467-024-48921-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P2X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SIT1:ACE2 complex (open PD conformation)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8P2W", "evidence_id": "EV-PDB-8P2W-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.76}, "provenance": {"deposit_id": "8P2W", "doi": "10.1038/s41467-024-48921-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8P2W"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human SIT1 (focussed map / refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8JYN", "evidence_id": "EV-PDB-8JYN-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8JYN", "doi": "10.1038/s41467-024-45274-3", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8JYN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 XBB.1.5 spike glycoprotein in complex with ACE2 (1-up state)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8HRU", "evidence_id": "EV-PDB-8HRU-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8HRU", "doi": "10.1038/s41467-024-51696-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8HRU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8H06", "evidence_id": "EV-PDB-8H06-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "8H06", "doi": "10.1038/s41467-023-39942-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8H06"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with human ACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8E7M", "evidence_id": "EV-PDB-8E7M-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8E7M", "doi": "10.1101/2022.08.24.505169", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8E7M"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the human ACE2 receptor in complex with antibody Fab fragment, 05B04"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion,Immunoglobulin gamma-1 heavy chain (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DV1", "evidence_id": "EV-PDB-8DV1-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8DV1", "doi": "10.1016/j.str.2023.01.009", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DV1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to linker variant of affinity matured ACE2 mimetic CVD432"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8DM5", "evidence_id": "EV-PDB-8DM5-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.51}, "provenance": {"deposit_id": "8DM5", "doi": "10.1016/j.celrep.2022.111964", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8DM5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NA", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UZE", "evidence_id": "EV-PDB-8UZE-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "8UZE", "doi": "10.1073/pnas.2322600121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UZE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric bat coronavirus BANAL-20-236 RBD complexed with chimeric mouse ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,G)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WLZ", "evidence_id": "EV-PDB-8WLZ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.45}, "provenance": {"deposit_id": "8WLZ", "doi": "10.1128/jvi.00342-24", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WLZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of the WIV1 S-hACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRO", "evidence_id": "EV-PDB-8WRO-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.9}, "provenance": {"deposit_id": "8WRO", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5.10 spike protein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WTJ", "evidence_id": "EV-PDB-8WTJ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.64}, "provenance": {"deposit_id": "8WTJ", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WTJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5.70 spike protein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XLM", "evidence_id": "EV-PDB-8XLM-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "8XLM", "doi": "10.1111/1348-0421.13165", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XLM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein in complex with ACE2 (1-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XLN", "evidence_id": "EV-PDB-8XLN-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.78}, "provenance": {"deposit_id": "8XLN", "doi": "10.1111/1348-0421.13165", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XLN"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of the SARS-CoV-2 EG.5.1 spike RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,O)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUY", "evidence_id": "EV-PDB-8XUY-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.14}, "provenance": {"deposit_id": "8XUY", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains L)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XUZ", "evidence_id": "EV-PDB-8XUZ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "8XUZ", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XUZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up and 1-down state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XV0", "evidence_id": "EV-PDB-8XV0-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8XV0", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XV0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XV1", "evidence_id": "EV-PDB-8XV1-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.05}, "provenance": {"deposit_id": "8XV1", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XV1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (down state)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XYO", "evidence_id": "EV-PDB-8XYO-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8XYO", "doi": "10.1128/jvi.00283-25", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XYO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of CX1 receptor binding domain in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XYG", "evidence_id": "EV-PDB-8XYG-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.64}, "provenance": {"deposit_id": "8XYG", "doi": "10.1016/j.virol.2024.110241", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XYG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 BQ.1.1 RBD and human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XYE", "evidence_id": "EV-PDB-8XYE-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.32}, "provenance": {"deposit_id": "8XYE", "doi": "10.1016/j.virol.2024.110241", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XYE"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 BA.4 RBD and human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XY9", "evidence_id": "EV-PDB-8XY9-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.64}, "provenance": {"deposit_id": "8XY9", "doi": "10.1016/j.virol.2024.110241", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XY9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of SARS-CoV-2 BF.7 RBD and human ACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XXW", "evidence_id": "EV-PDB-8XXW-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.03}, "provenance": {"deposit_id": "8XXW", "doi": "10.1016/j.celrep.2024.114235", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XXW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Fab M2-7 complexed with SARS-Cov2 RBD and human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSJ", "evidence_id": "EV-PDB-8XSJ-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.61}, "provenance": {"deposit_id": "8XSJ", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XSF", "evidence_id": "EV-PDB-8XSF-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.16}, "provenance": {"deposit_id": "8XSF", "doi": "10.1016/j.celrep.2024.114338", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XSF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 RBD + IMCAS-364 + hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XNK", "evidence_id": "EV-PDB-8XNK-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.78}, "provenance": {"deposit_id": "8XNK", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XNK"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XNF", "evidence_id": "EV-PDB-8XNF-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.26}, "provenance": {"deposit_id": "8XNF", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XNF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XN5", "evidence_id": "EV-PDB-8XN5-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.87}, "provenance": {"deposit_id": "8XN5", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XN5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XN3", "evidence_id": "EV-PDB-8XN3-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.64}, "provenance": {"deposit_id": "8XN3", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XN3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XN2", "evidence_id": "EV-PDB-8XN2-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.79}, "provenance": {"deposit_id": "8XN2", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XN2"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2,Green fluorescent protein (Fragment) (chains I,J)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8XAL", "evidence_id": "EV-PDB-8XAL-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8XAL", "doi": "10.1172/jci.insight.179726", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8XAL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains T,X,Z)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WYH", "evidence_id": "EV-PDB-8WYH-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.0}, "provenance": {"deposit_id": "8WYH", "doi": "10.1038/s41467-024-51973-8", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WYH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The global map of Omicron Subvariants Spike with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WTD", "evidence_id": "EV-PDB-8WTD-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "8WTD", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WTD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5.10 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WSR", "evidence_id": "EV-PDB-8WSR-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "8WSR", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WSR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "The structure of LS1_RBD/hACE2 protein"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRM", "evidence_id": "EV-PDB-8WRM-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.34}, "provenance": {"deposit_id": "8WRM", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRM"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 spike protein in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRL", "evidence_id": "EV-PDB-8WRL-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.36}, "provenance": {"deposit_id": "8WRL", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRL"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "XBB.1.5 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WRH", "evidence_id": "EV-PDB-8WRH-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.08}, "provenance": {"deposit_id": "8WRH", "doi": "10.1371/journal.ppat.1011868", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WRH"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 XBB.1.5.70 in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WP8", "evidence_id": "EV-PDB-8WP8-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.89}, "provenance": {"deposit_id": "8WP8", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WP8"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "TGI", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WM3", "evidence_id": "EV-PDB-8WM3-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.34}, "provenance": {"deposit_id": "8WM3", "doi": "10.1016/j.jbc.2024.107687", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WM3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of ACE2-SIT1 complex with tiagabine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHZ", "evidence_id": "EV-PDB-8WHZ-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.93}, "provenance": {"deposit_id": "8WHZ", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2.86 RBD in complex with hACE2 (local refinement)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHU", "evidence_id": "EV-PDB-8WHU-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8WHU", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike Trimer of BA.2.86 in complex with two hACE2s"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WHS", "evidence_id": "EV-PDB-8WHS-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.33}, "provenance": {"deposit_id": "8WHS", "doi": "10.1093/nsr/nwae206", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WHS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Spike Trimer of BA.2.86 in complex with one hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WGW", "evidence_id": "EV-PDB-8WGW-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "8WGW", "doi": "10.1038/s41590-024-01776-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WGW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of RBD-ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WGV", "evidence_id": "EV-PDB-8WGV-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.92}, "provenance": {"deposit_id": "8WGV", "doi": "10.1038/s41590-024-01776-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WGV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BA.2(S375) Spike (S6P)/hACE2 complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WE4", "evidence_id": "EV-PDB-8WE4-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.91}, "provenance": {"deposit_id": "8WE4", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WE4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WE1", "evidence_id": "EV-PDB-8WE1-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.47}, "provenance": {"deposit_id": "8WE1", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WE1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BF.7 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WE0", "evidence_id": "EV-PDB-8WE0-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "8WE0", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WE0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron XBB RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDZ", "evidence_id": "EV-PDB-8WDZ-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "8WDZ", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BQ.1 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDY", "evidence_id": "EV-PDB-8WDY-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "8WDY", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BQ.1.1 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": 17.85}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDS", "evidence_id": "EV-PDB-8WDS-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8WDS", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of BF.7 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WDR", "evidence_id": "EV-PDB-8WDR-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.47}, "provenance": {"deposit_id": "8WDR", "doi": "10.1038/s44318-024-00062-z", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WDR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of BQ.1.1 RBD complexed with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "XF0", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WBZ", "evidence_id": "EV-PDB-8WBZ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.2}, "provenance": {"deposit_id": "8WBZ", "doi": "10.1038/s41467-024-51748-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WBZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of ACE2-B0AT1 complex with JX225"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "WM8", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B,C)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8WBY", "evidence_id": "EV-PDB-8WBY-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.18}, "provenance": {"deposit_id": "8WBY", "doi": "10.1038/s41467-024-51748-1", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8WBY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of ACE2-B0AT1 complex with JX98"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme,Processed angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VQR", "evidence_id": "EV-PDB-8VQR-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.565}, "provenance": {"deposit_id": "8VQR", "doi": "10.1371/journal.ppat.1012204", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VQR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric SARS-CoV-2 RBD complexed with chimeric raccoon dog ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKP", "evidence_id": "EV-PDB-8VKP-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.77}, "provenance": {"deposit_id": "8VKP", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8VKO", "evidence_id": "EV-PDB-8VKO-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.68}, "provenance": {"deposit_id": "8VKO", "doi": "10.1038/s41467-024-46104-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8VKO"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "EDO", "NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8UZF", "evidence_id": "EV-PDB-8UZF-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.283}, "provenance": {"deposit_id": "8UZF", "doi": "10.1073/pnas.2322600121", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8UZF"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of chimeric RaTG13 RBD complexed with chimeric mouse ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y16", "evidence_id": "EV-PDB-8Y16-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.98}, "provenance": {"deposit_id": "8Y16", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y16"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Y18", "evidence_id": "EV-PDB-8Y18-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.04}, "provenance": {"deposit_id": "8Y18", "doi": "10.1016/j.str.2024.06.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Y18"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 Omicron JN.1 RBD in complex with human ACE2 (local refinement from the spike protein)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z4X", "evidence_id": "EV-PDB-8Z4X-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.4}, "provenance": {"deposit_id": "8Z4X", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z4X"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G S with two ACE2 receptors binding (RB2) in prefusion conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z64", "evidence_id": "EV-PDB-8Z64-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.53}, "provenance": {"deposit_id": "8Z64", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z64"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G S with three ACE2 receptors binding (RB3) in prefusion conformation (focused refinement of NTD-SD1-RBD-ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z6A", "evidence_id": "EV-PDB-8Z6A-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.99}, "provenance": {"deposit_id": "8Z6A", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z6A"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 D614G S with three ACE2 receptors binding (RB3) in prefusion conformation"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z7B", "evidence_id": "EV-PDB-8Z7B-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "8Z7B", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z7B"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of NTD-SD1-RBD-ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8Z7P", "evidence_id": "EV-PDB-8Z7P-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.45}, "provenance": {"deposit_id": "8Z7P", "doi": "10.1016/j.cell.2025.01.012", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8Z7P"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2 (chains A,C,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9BNG", "evidence_id": "EV-PDB-9BNG-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.73}, "provenance": {"deposit_id": "9BNG", "doi": "10.1038/s42003-025-08819-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9BNG"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 spike HexaPro protein in complex with T18A trimeric antagonist"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose", "branched: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IU1", "evidence_id": "EV-PDB-9IU1-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.3}, "provenance": {"deposit_id": "9IU1", "doi": "10.1038/s41467-024-52808-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IU1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of SARS-CoV-2 JN.1 spike RBD in complex with ACE2 (up state)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IUP", "evidence_id": "EV-PDB-9IUP-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.3}, "provenance": {"deposit_id": "9IUP", "doi": "10.1038/s41421-024-00752-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IUP"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "KP.3 RBD in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9IUU", "evidence_id": "EV-PDB-9IUU-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.29}, "provenance": {"deposit_id": "9IUU", "doi": "10.1038/s41421-024-00752-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9IUU"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "JN.1 RBD with Q493E in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9JJ6", "evidence_id": "EV-PDB-9JJ6-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.94}, "provenance": {"deposit_id": "9JJ6", "doi": "10.1016/j.cell.2025.01.042", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9JJ6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "BtHKU5-CoV-2-441 Spike RBD domain binding to hACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NA", "NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXW", "evidence_id": "EV-PDB-9KXW-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.66}, "provenance": {"deposit_id": "9KXW", "doi": "10.1038/s42003-026-10535-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXW"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human B0AT1-ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1L6U", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXY", "evidence_id": "EV-PDB-9KXY-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.82}, "provenance": {"deposit_id": "9KXY", "doi": "10.1038/s42003-026-10535-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human B0AT1-ACE2 complex with compound1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9LDJ", "evidence_id": "EV-PDB-9LDJ-4", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.21}, "provenance": {"deposit_id": "9LDJ", "doi": "10.1038/s41586-026-10462-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9LDJ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 wide-type S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UE7", "evidence_id": "EV-PDB-9UE7-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.27}, "provenance": {"deposit_id": "9UE7", "doi": "10.1038/s41467-025-66018-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UE7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 KP.2 spike in complex with ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XHZ", "evidence_id": "EV-PDB-9XHZ-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.28}, "provenance": {"deposit_id": "9XHZ", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XHZ"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C092 Fab and ACE2 (2 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI0", "evidence_id": "EV-PDB-9XI0-4", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.98}, "provenance": {"deposit_id": "9XI0", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI0"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C092 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XHY", "evidence_id": "EV-PDB-9XHY-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.84}, "provenance": {"deposit_id": "9XHY", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XHY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with C092 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9VLT", "evidence_id": "EV-PDB-9VLT-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 5.65}, "provenance": {"deposit_id": "9VLT", "doi": "10.1038/s41586-026-10462-2", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9VLT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9UE6", "evidence_id": "EV-PDB-9UE6-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.9}, "provenance": {"deposit_id": "9UE6", "doi": "10.1038/s41467-025-66018-x", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9UE6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of SARS-CoV-2 KP.2 spike RBD in complex with ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.0, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B,D,G)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RVT", "evidence_id": "EV-PDB-9RVT-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.39}, "provenance": {"deposit_id": "9RVT", "doi": "10.1021/acs.jmedchem.5c02876", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RVT"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "ACE2 extracellular domain in complex with the macrocyclic peptide GR1.4"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["2PE", "CL", "EDO", "IPA", "NA", "NAG", "SO4", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9RVA", "evidence_id": "EV-PDB-9RVA-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.2}, "provenance": {"deposit_id": "9RVA", "doi": "10.1016/j.yjsbx.2026.100145", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9RVA"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of the extracellular part of human ACE2 in complex with the macrocyclic peptide WJL-63"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["CL", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A,B,C)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9R19", "evidence_id": "EV-PDB-9R19-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.69}, "provenance": {"deposit_id": "9R19", "doi": "10.1038/s41467-025-65144-w", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9R19"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Crystal structure of human ACE2 in complex with VHH B07 and VHH B10"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B,D)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KY1", "evidence_id": "EV-PDB-9KY1-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.8}, "provenance": {"deposit_id": "9KY1", "doi": "10.1038/s42003-026-10535-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KY1"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human B0AT1-ACE2 complex with compound1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["A1L6W", "NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9KXV", "evidence_id": "EV-PDB-9KXV-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.71}, "provenance": {"deposit_id": "9KXV", "doi": "10.1038/s42003-026-10535-y", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9KXV"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of human B0AT1-ACE2 complex with compound3"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9J62", "evidence_id": "EV-PDB-9J62-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.76}, "provenance": {"deposit_id": "9J62", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9J62"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of Bat SARS-like coronavirus Khosta-2 spike protein in complex with human ACE2 (local refined)"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains B)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YZD", "evidence_id": "EV-PDB-8YZD-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.07}, "provenance": {"deposit_id": "8YZD", "doi": "10.1038/s41467-024-53033-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YZD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of JN.1 RBD protein in complex with ACE2."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains G,H,I)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/8YZC", "evidence_id": "EV-PDB-8YZC-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.7}, "provenance": {"deposit_id": "8YZC", "doi": "10.1038/s41467-024-53033-7", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/8YZC"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Structure of BA.2.86 spike protein in complex with ACE2."}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI3", "evidence_id": "EV-PDB-9XI3-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 4.74}, "provenance": {"deposit_id": "9XI3", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI3"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with C807 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI4", "evidence_id": "EV-PDB-9XI4-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.83}, "provenance": {"deposit_id": "9XI4", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI4"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with BD56-104 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI5", "evidence_id": "EV-PDB-9XI5-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.06}, "provenance": {"deposit_id": "9XI5", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with BD56-104 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI6", "evidence_id": "EV-PDB-9XI6-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.6}, "provenance": {"deposit_id": "9XI6", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike RBD in complex with BD56-597 Fab and ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "ZN", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Processed angiotensin-converting enzyme 2 (chains D,E,F)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9XI7", "evidence_id": "EV-PDB-9XI7-2", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.22}, "provenance": {"deposit_id": "9XI7", "doi": null, "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9XI7"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "SARS-CoV-2 Omicron BA.4/5 spike trimer in complex with BD56-597 Fab and ACE2 (3 RBD up)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YSR", "evidence_id": "EV-PDB-9YSR-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.63}, "provenance": {"deposit_id": "9YSR", "doi": "10.1016/j.celrep.2026.117812", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YSR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of hACE2/SARS-CoV-2 BA.3.2.1 spike, conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": ["NAG", "branched: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose"], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Angiotensin-converting enzyme 2 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/9YSS", "evidence_id": "EV-PDB-9YSS-1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 3.67}, "provenance": {"deposit_id": "9YSS", "doi": "10.1016/j.celrep.2026.117812", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/9YSS"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Local refinement of hACE2/SARS-CoV-2 LP.8.1 spike, conformation 1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 2.5, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=34650", "evidence_id": "EV-BMRB-34650", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr34650", "doi": "10.13018/BMR34650", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=34650"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR structure of human ACE2 21-42 fragment in HFIP/water 50/50 v/v"}
{"conditions": {"applied_force_pn": null, "buffer": "50mM Tris, 200mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 27.48 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Angiotensin Converting Enzyme2", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXW6/", "evidence_id": "EV-SASBDB-SASDXW6", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "radius_of_gyration", "uncertainty": 1.752, "unit": "nm", "value": 5.446}, "provenance": {"deposit_id": "SASDXW6", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXW6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "ACE 2 protein"}
{"conditions": {"applied_force_pn": null, "buffer": "50mM Tris, 200mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Receptor Binding Domain"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 21.36 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Angiotensin converting Enzyme 2 with Receptor Binding Domain", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDXX6/", "evidence_id": "EV-SASBDB-SASDXX6", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "radius_of_gyration", "uncertainty": 0.562, "unit": "nm", "value": 6.709}, "provenance": {"deposit_id": "SASDXX6", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDXX6/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "ACE2 RBD Complex"}
{"conditions": {"applied_force_pn": null, "buffer": "50mM Tris, 150mM NaCl", "environment": "in_vitro", "ions": [], "ligands": ["partner: Spike glycoprotein"], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 11.42 nm.", "ph": 8.0, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Angiotensin-converting enzyme 2 with Spike glycoprotein", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDYG7/", "evidence_id": "EV-SASBDB-SASDYG7", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "radius_of_gyration", "uncertainty": 0.896, "unit": "nm", "value": 4.393}, "provenance": {"deposit_id": "SASDYG7", "doi": null, "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDYG7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "ACE 2 RBD with Umifenovir"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "DisProt annotations do not record sample conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "residues 769-805; evidence: cryogenic electron microscopy-based structural model with missing residue coordinates used in manual assertion", "labels": []}, "data_format": null, "data_level": "reported", "data_link": "https://europepmc.org/article/MED/32132184", "evidence_id": "EV-DISPROT-DP02854r001", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "disorder_region", "uncertainty": null, "unit": "residues", "value": 37}, "provenance": {"deposit_id": "DP02854r001", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "DisProt", "url": "https://disprot.org/DP02854"}, "reader": null, "record_type": "evidence", "source_kind": "literature", "technique": "cryoem", "title": "DisProt DP02854: disorder, residues 769-805"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-805", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/Q9BYF1", "evidence_id": "EV-AFDB-AF-Q9BYF1-F1", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 90.69}, "provenance": {"deposit_id": "AF-Q9BYF1-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/Q9BYF1"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-Q9BYF1-F1"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "start 6VW1; force field not stated", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/MCV1900002/overview", "evidence_id": "EV-MDDB-MCV1900002", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 200.0}, "provenance": {"deposit_id": "MCV1900002", "doi": null, "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/MCV1900002/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "SARS spike receptor binding domain bound with FERR ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "start 6VW1; force field not stated", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/MCV1900004/overview", "evidence_id": "EV-MDDB-MCV1900004", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 200.0}, "provenance": {"deposit_id": "MCV1900004", "doi": null, "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/MCV1900004/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "Human Angiotensin-converting enzyme 2 (ACE2)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "start 6VW1; force field not stated", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/MCV1900013/overview", "evidence_id": "EV-MDDB-MCV1900013", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 200.0}, "provenance": {"deposit_id": "MCV1900013", "doi": null, "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/MCV1900013/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "Bat-SARSr-CoV RATG13 spike receptor binding domain bound with Rhinolophus Affinis ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "start 6VW1; force field not stated", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/MCV1900014/overview", "evidence_id": "EV-MDDB-MCV1900014", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 200.0}, "provenance": {"deposit_id": "MCV1900014", "doi": null, "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/MCV1900014/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "Bat-SARSr-CoV RATG13 spike receptor binding domain bound with FERR ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "start 6VW1; force field not stated", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/MCV1900015/overview", "evidence_id": "EV-MDDB-MCV1900015", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 200.0}, "provenance": {"deposit_id": "MCV1900015", "doi": null, "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/MCV1900015/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "Bat-SARSr-CoV RATG13 spike receptor binding domain bound with MACR ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "start 6VW1; force field not stated", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/MCV1900016/overview", "evidence_id": "EV-MDDB-MCV1900016", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 200.0}, "provenance": {"deposit_id": "MCV1900016", "doi": null, "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/MCV1900016/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "Bat-SARSr-CoV RATG13 spike receptor binding domain bound with Pangolin ACE2"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Simulation; temperature is the thermostat setting.", "ph": null, "salt_mM": null, "temperature_c": 36.85}, "construct": {"description": "start 6VW1; force field not stated", "labels": []}, "data_format": "trajectory", "data_level": "processed", "data_link": "https://mmb.mddbr.eu/#/id/MCV1900017/overview", "evidence_id": "EV-MDDB-MCV1900017", "mappings": [], "molecule_id": "Q9BYF1", "observable": {"type": "trajectory", "uncertainty": null, "unit": "ns", "value": 200.0}, "provenance": {"deposit_id": "MCV1900017", "doi": null, "licence": "This trajectory dataset is released under a Creative Commons Attribution 4.0 International Public License", "retrieved": "2026-10-19", "source": "MDDB", "url": "https://mmb.mddbr.eu/#/id/MCV1900017/overview"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "md", "title": "Bat-SARSr-CoV RATG13 spike receptor binding domain bound with PUS ACE2"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.5, "salt_mM": null, "temperature_c": 9.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=25545", "evidence_id": "EV-BMRB-25545", "mappings": [], "molecule_id": "Q9UM54", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr25545", "doi": "10.13018/BMR25545", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=25545"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "Complex structure of MyUb (1080-1122) of human Myosin VI with K63-diUb"}
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{"assumptions": [], "basis": "observed", "description": "Full-length talin-1 folded into a compact autoinhibited arrangement, as in 6R9T (cryo-EM, 6.2 Å).", "family_label": null, "molecule_id": "Q9Y490", "name": "autoinhibited, compact", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (Q9Y490.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/Q9Y490.yaml"}, "record_type": "state", "representative_model": "talin-autoinhibited-cif", "secondary_structure": null, "state_id": "talin-autoinhibited", "status": "draft"}
{"assumptions": ["Defined from force spectroscopy of rod domains; no structure of the force-unfolded rod exists.", "Vinculin-bound VBS peptide structures show the exposed helix only, not the rod.", "Bundles are treated together; which bundles unfold at which force is not resolved here. No model is exported."], "basis": "inferred", "description": "Rod helical bundles unfolded by mechanical load, exposing vinculin-binding helices.", "family_label": null, "molecule_id": "Q9Y490", "name": "rod unfolded under force (vinculin-binding sites exposed)", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (Q9Y490.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/Q9Y490.yaml"}, "record_type": "state", "representative_model": null, "secondary_structure": null, "state_id": "talin-rod-unfolded", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": 7.5, "salt_mM": null, "temperature_c": -173.15}, "construct": {"description": "Talin-1 (chains B)", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/4DJ9", "evidence_id": "EV-PDB-4DJ9-2", "mappings": [{"confidence": "low", "justification": "Isolated talin vinculin-binding-site peptide bound to vinculin: the exposed helix, the end point of rod unfolding.", "rule": "talin-vbs-vinculin", "state_id": "talin-rod-unfolded", "who": "rule:talin-vbs-vinculin"}], "molecule_id": "Q9Y490", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.25}, "provenance": {"deposit_id": "4DJ9", "doi": "10.1002/pro.2041", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/4DJ9"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Entry-level ligand list; oligosaccharides appear as branched entities. pH and temperature are null when not deposited in machine-readable fields.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Talin-1 (chains A)", "labels": []}, "data_format": "mmCIF + EMDB map", "data_level": "processed", "data_link": "https://www.rcsb.org/structure/6R9T", "evidence_id": "EV-PDB-6R9T-1", "mappings": [{"confidence": "high", "justification": "Title: cryo-EM structure of autoinhibited human talin-1.", "rule": "curator_assignment", "state_id": "talin-autoinhibited", "who": "curator:draft (unreviewed)"}], "molecule_id": "Q9Y490", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 6.2}, "provenance": {"deposit_id": "6R9T", "doi": "10.1016/j.cell.2019.08.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://www.rcsb.org/structure/6R9T"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "cryoem", "title": "Cryo-EM structure of autoinhibited human talin-1"}
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{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [], "ligands": [], "notes": "From the first sample condition list of the entry.", "ph": 6.3, "salt_mM": null, "temperature_c": 24.85}, "construct": {"description": "BMRB data: 13C chemical shifts, 15N chemical shifts, 1H chemical shifts", "labels": []}, "data_format": "NMR-STAR", "data_level": "processed", "data_link": "https://bmrb.io/data_library/summary/index.php?bmrbId=7061", "evidence_id": "EV-BMRB-7061", "mappings": [], "molecule_id": "Q9Y490", "observable": {"type": "chemical_shift", "uncertainty": null, "unit": null, "value": null}, "provenance": {"deposit_id": "bmr7061", "doi": "10.13018/BMR7061", "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "BMRB", "url": "https://bmrb.io/data_library/summary/index.php?bmrbId=7061"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "nmr_shifts", "title": "NMR structure of talin-PTB in complex with PIPKI"}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM sodium phosphate, 150mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 13.25 nm.", "ph": 7.2, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Talin-1 (Δ139-168), human", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDFS7/", "evidence_id": "EV-SASBDB-SASDFS7", "mappings": [], "molecule_id": "Q9Y490", "observable": {"type": "radius_of_gyration", "uncertainty": 0.08, "unit": "nm", "value": 3.28}, "provenance": {"deposit_id": "SASDFS7", "doi": "10.1242/jcs.239202", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDFS7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering."}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM sodium phosphate, 150 mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 11.49 nm.", "ph": 7.2, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Talin-1, human", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDFT7/", "evidence_id": "EV-SASBDB-SASDFT7", "mappings": [], "molecule_id": "Q9Y490", "observable": {"type": "radius_of_gyration", "uncertainty": 0.02, "unit": "nm", "value": 3.35}, "provenance": {"deposit_id": "SASDFT7", "doi": "10.1242/jcs.239202", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDFT7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering."}
{"conditions": {"applied_force_pn": null, "buffer": "50 mM sodium phosphate, 150mM NaCl", "environment": "in_vitro", "ions": [], "ligands": [], "notes": "Other molecules in the sample are listed as partners; Rg is of the whole sample. Dmax 10.19 nm.", "ph": 7.2, "salt_mM": null, "temperature_c": 10.0}, "construct": {"description": "Talin-1 (Δ134-170/GAG insert), human", "labels": []}, "data_format": "scattering curve", "data_level": "processed", "data_link": "https://www.sasbdb.org/data/SASDFU7/", "evidence_id": "EV-SASBDB-SASDFU7", "mappings": [], "molecule_id": "Q9Y490", "observable": {"type": "radius_of_gyration", "uncertainty": 0.08, "unit": "nm", "value": 3.02}, "provenance": {"deposit_id": "SASDFU7", "doi": "10.1242/jcs.239202", "licence": "CC BY 4.0 (verify)", "retrieved": "2026-10-19", "source": "SASBDB", "url": "https://www.sasbdb.org/data/SASDFU7/"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "saxs_sans", "title": "The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering."}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_silico", "ions": [], "ligands": [], "notes": "Computed prediction; no experimental conditions.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "AlphaFold Monomer v2.0 pipeline, residues 1-2541", "labels": []}, "data_format": "mmCIF, PAE JSON", "data_level": "processed", "data_link": "https://alphafold.ebi.ac.uk/entry/Q9Y490", "evidence_id": "EV-AFDB-AF-Q9Y490-F1", "mappings": [], "molecule_id": "Q9Y490", "observable": {"type": "plddt", "uncertainty": null, "unit": "pLDDT", "value": 75.88}, "provenance": {"deposit_id": "AF-Q9Y490-F1", "doi": null, "licence": "CC BY 4.0", "retrieved": "2026-10-19", "source": "AlphaFold DB", "url": "https://alphafold.ebi.ac.uk/entry/Q9Y490"}, "reader": null, "record_type": "evidence", "source_kind": "computed", "technique": "af_prediction", "title": "AlphaFold DB prediction AF-Q9Y490-F1"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-6R9T-1"], "file": "models/Q9Y490/talin-autoinhibited.cif", "format": "mmCIF", "model_id": "talin-autoinhibited-cif", "molecule_id": "Q9Y490", "provenance": {"deposit_id": "6R9T", "doi": "10.1016/j.cell.2019.08.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/6R9T.cif"}, "record_type": "model", "state_id": "talin-autoinhibited"}
{"assumptions": null, "basis": "observed", "constraints_used": ["EV-PDB-6R9T-1"], "file": "models/Q9Y490/talin-autoinhibited.pdb", "format": "PDB", "model_id": "talin-autoinhibited-pdb", "molecule_id": "Q9Y490", "provenance": {"deposit_id": "6R9T", "doi": "10.1016/j.cell.2019.08.034", "licence": "CC0 1.0 (wwPDB archive data)", "retrieved": "2026-10-19", "source": "RCSB PDB", "url": "https://files.rcsb.org/download/6R9T.pdb"}, "record_type": "model", "state_id": "talin-autoinhibited"}
{"components": [], "domains": [{"end": 69, "name": "Purine riboswitch aptamer (Rfam RF00167)", "start": 2}], "gene": null, "identifiers": {"genbank": null, "isoform": null, "nakb": null, "pdb": [], "rfam": "RF00167", "rnacentral": "URS000080DF85_672", "uniprot": null}, "ligands": [], "modifications": [], "molecule_id": "URS000080DF85_672", "molecule_type": "rna", "name": "A-riboswitch from Vibrio vulnificus (PDB 1Y26, chain X)", "organism": {"name": "Vibrio vulnificus", "taxon_id": 672}, "provenance": {"deposit_id": "URS000080DF85_672", "doi": null, "licence": "CC0 1.0 (verify)", "retrieved": "2026-10-19", "source": "RNAcentral", "url": "https://rnacentral.org/rna/URS000080DF85/672"}, "record_type": "molecule", "sequence": "CGCUUCAUAUAAUCCUAAUGAUAUGGUUUGGGAGUUUCUACCAAGAGCCUUAAACUCUUGAUUAUGAAGUG", "sequence_length": 71}
{"assumptions": [], "basis": "observed", "description": "Aptamer without adenine, as in 5E54 (room-temperature XFEL structure; two conformers in the asymmetric unit, apo1 and apo2, which differ in the length of P1). The 5E54 construct has a different P1 sequence from this page's sequence, so no pairing is given here.", "family_label": {"terms": {"aptamer": "aptamer_unbound"}, "vocabulary": "riboswitch"}, "molecule_id": "URS000080DF85_672", "name": "ligand-free aptamer", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (URS000080DF85_672.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/URS000080DF85_672.yaml"}, "record_type": "state", "representative_model": "ADD-apo-cif", "secondary_structure": null, "state_id": "ADD-apo", "status": "draft"}
{"assumptions": [], "basis": "observed", "description": "Adenine bound to an aptamer that has not yet reached the fully bound fold, trapped by mix-and-inject serial crystallography, as in 5SWD. Same construct as 5E54.", "family_label": null, "molecule_id": "URS000080DF85_672", "name": "ligand-bound intermediate", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (URS000080DF85_672.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/URS000080DF85_672.yaml"}, "record_type": "state", "representative_model": "ADD-intermediate-cif", "secondary_structure": null, "state_id": "ADD-intermediate", "status": "draft"}
{"assumptions": [], "basis": "observed", "description": "Aptamer folded around adenine, as in 1Y26 (2.1 Å, Mg2+): P1, P2 and P3 around a three-way junction, the L2-L3 kissing loop (G37-C61, G38-C60; brackets [ ]), the U22-A52 pair of the binding pocket (brackets { }) and adenine paired with U74.", "family_label": {"terms": {"aptamer": "aptamer_bound"}, "vocabulary": "riboswitch"}, "molecule_id": "URS000080DF85_672", "name": "adenine-bound aptamer", "parent_state": null, "population": null, "provenance": {"deposit_id": null, "doi": null, "licence": "Project licence (pending decision)", "retrieved": "2026-10-19", "source": "Conformome curation (URS000080DF85_672.yaml)", "url": "https://github.com/matth55/conformome/blob/HEAD/curation/URS000080DF85_672.yaml"}, "record_type": "state", "representative_model": "ADD-bound-cif", "secondary_structure": {"dot_bracket": "((((((((({..((((((......[[.))))))(.....})((((((]].....))))))..)))))))))", "source": "1Y26, canonical cWW pairs from FR3D (BGSU RNA 3D Hub), author numbering 13-83 = positions 1-71"}, "state_id": "ADD-bound", "status": "draft"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}], "ligands": ["ADE"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Vibrio vulnificus A-riboswitch (chains X); same sequence", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=1Y26", "evidence_id": "EV-NAKB-1Y26-1", "mappings": [{"confidence": "high", "justification": "Adenine (ADE) bound, this exact sequence; anchor structure.", "rule": "curator_assignment", "state_id": "ADD-bound", "who": "curator:draft (unreviewed)"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.1}, "provenance": {"deposit_id": "1Y26", "doi": "10.1016/j.chembiol.2004.11.018", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=1Y26"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "A-riboswitch-adenine complex"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}], "ligands": ["29G"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Mutated adenine riboswitch aptamer (chains A); other construct of the same Rfam family (RF00167) and organism, 71 nt", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=4LX5", "evidence_id": "EV-NAKB-4LX5-1", "mappings": [{"confidence": "low", "justification": "Engineered M6'' aptamer bound to a synthetic ligand (PPDA) instead of adenine; bound fold assumed similar.", "rule": "curator_assignment", "state_id": "ADD-bound", "who": "curator:draft (unreviewed)"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.13}, "provenance": {"deposit_id": "4LX5", "doi": "10.1021/ja502873j", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=4LX5"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystal structure of the M6\" riboswitch aptamer bound to pyrimido[4,5-d]pyrimidine-2,4-diamine (PPDA)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}], "ligands": ["29H"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Mutated adenine riboswitch aptamer (chains A); other construct of the same Rfam family (RF00167) and organism, 71 nt", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=4LX6", "evidence_id": "EV-NAKB-4LX6-1", "mappings": [{"confidence": "low", "justification": "Engineered M6C'' aptamer bound to a synthetic ligand (PPAO) instead of adenine; bound fold assumed similar.", "rule": "curator_assignment", "state_id": "ADD-bound", "who": "curator:draft (unreviewed)"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.15}, "provenance": {"deposit_id": "4LX6", "doi": "10.1021/ja502873j", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=4LX6"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "X-ray crystal structure of the M6C\" riboswitch aptamer bound to 2-aminopyrimido[4,5-d]pyrimidin-4(3H)-one (PPAO)"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}], "ligands": ["ADE"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Vibrio vulnificus Adenine Riboswitch (chains X); other construct of the same Rfam family (RF00167) and organism, 71 nt", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=4TZX", "evidence_id": "EV-NAKB-4TZX-1", "mappings": [{"confidence": "medium", "justification": "Structure with adenine modelled and not titled as an intermediate or transitional state; adenine-bound aptamer structures share the bound fold.", "rule": "add-adenine-bound", "state_id": "ADD-bound", "who": "rule:add-adenine-bound"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.01}, "provenance": {"deposit_id": "4TZX", "doi": "10.1016/j.str.2014.07.011", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=4TZX"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Vibrio Vulnificus Adenine Riboswitch variant, grown in Mg2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}, {"concentration_mM": null, "ion": "Sr2+"}], "ligands": ["ADE"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Vibrio vulnificus Adenine Riboswitch (chains X); other construct of the same Rfam family (RF00167) and organism, 71 nt", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=4TZY", "evidence_id": "EV-NAKB-4TZY-1", "mappings": [{"confidence": "medium", "justification": "Structure with adenine modelled and not titled as an intermediate or transitional state; adenine-bound aptamer structures share the bound fold.", "rule": "add-adenine-bound", "state_id": "ADD-bound", "who": "rule:add-adenine-bound"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.57}, "provenance": {"deposit_id": "4TZY", "doi": "10.1016/j.str.2014.07.011", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=4TZY"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Vibrio vulnificus Adenine Riboswitch Variant, grown in both Sr2+ and Mg2+"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}], "ligands": ["ADE"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Vibrio Vulnificus Adenine Riboswitch (chains X); other construct of the same Rfam family (RF00167) and organism, 71 nt", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=4XNR", "evidence_id": "EV-NAKB-4XNR-1", "mappings": [{"confidence": "high", "justification": "Title: aptamer domain in complex with adenine (PLOR-synthesised).", "rule": "curator_assignment", "state_id": "ADD-bound", "who": "curator:draft (unreviewed)"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.21}, "provenance": {"deposit_id": "4XNR", "doi": "10.1038/nature14352", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=4XNR"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}], "ligands": [], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain (chains A,B); other construct of the same Rfam family (RF00167) and organism, 71 nt", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=5E54", "evidence_id": "EV-NAKB-5E54-1", "mappings": [{"confidence": "high", "justification": "Title: two apo structures of the aptamer domain; no adenine modelled.", "rule": "curator_assignment", "state_id": "ADD-apo", "who": "curator:draft (unreviewed)"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.3}, "provenance": {"deposit_id": "5E54", "doi": "10.1038/nature20599", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=5E54"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Two apo structures of the adenine riboswitch aptamer domain determined using an X-ray free electron laser"}
{"conditions": {"applied_force_pn": null, "buffer": null, "environment": "in_vitro", "ions": [{"concentration_mM": null, "ion": "Mg2+"}], "ligands": ["ADE"], "notes": "Ligands and ions are those modelled in the entry; concentrations, pH and temperature are not in NAKB's index.", "ph": null, "salt_mM": null, "temperature_c": null}, "construct": {"description": "Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain (chains A,B); other construct of the same Rfam family (RF00167) and organism, 71 nt", "labels": []}, "data_format": "mmCIF + structure factors", "data_level": "processed", "data_link": "https://www.nakb.org/atlas=5SWD", "evidence_id": "EV-NAKB-5SWD-1", "mappings": [{"confidence": "high", "justification": "Title: aptamer domain in an intermediate-bound state.", "rule": "curator_assignment", "state_id": "ADD-intermediate", "who": "curator:draft (unreviewed)"}], "molecule_id": "URS000080DF85_672", "observable": {"type": "resolution", "uncertainty": null, "unit": "Å", "value": 2.5}, "provenance": {"deposit_id": "5SWD", "doi": "10.1038/nature20599", "licence": "PDB-derived fields: CC0 1.0 (wwPDB archive); NAKB annotations not used", "retrieved": "2026-10-19", "source": "NAKB", "url": "https://www.nakb.org/atlas=5SWD"}, "reader": null, "record_type": "evidence", "source_kind": "deposit", "technique": "xray", "title": "Structure of the adenine riboswitch aptamer domain in an intermediate-bound state"}
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